Amino acid dipepetide frequency for Apple rubbery wood virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.943AlaAla: 2.943 ± 2.722
0.0AlaCys: 0.0 ± 0.0
2.616AlaAsp: 2.616 ± 0.207
1.308AlaGlu: 1.308 ± 1.098
2.616AlaPhe: 2.616 ± 2.414
0.327AlaGly: 0.327 ± 0.157
0.654AlaHis: 0.654 ± 0.314
3.924AlaIle: 3.924 ± 0.981
4.251AlaLys: 4.251 ± 3.006
2.943AlaLeu: 2.943 ± 0.966
0.327AlaMet: 0.327 ± 0.157
2.289AlaAsn: 2.289 ± 1.088
0.654AlaPro: 0.654 ± 0.314
0.327AlaGln: 0.327 ± 0.157
0.654AlaArg: 0.654 ± 0.549
3.27AlaSer: 3.27 ± 1.05
1.308AlaThr: 1.308 ± 0.797
0.654AlaVal: 0.654 ± 0.314
0.327AlaTrp: 0.327 ± 0.759
2.616AlaTyr: 2.616 ± 3.012
0.0AlaXaa: 0.0 ± 0.0
Cys
0.327CysAla: 0.327 ± 0.157
0.0CysCys: 0.0 ± 0.0
0.981CysAsp: 0.981 ± 0.572
1.308CysGlu: 1.308 ± 0.394
1.308CysPhe: 1.308 ± 0.628
0.0CysGly: 0.0 ± 0.0
0.654CysHis: 0.654 ± 0.314
0.981CysIle: 0.981 ± 0.572
1.635CysLys: 1.635 ± 0.525
3.597CysLeu: 3.597 ± 1.093
0.0CysMet: 0.0 ± 0.0
0.981CysAsn: 0.981 ± 0.451
0.327CysPro: 0.327 ± 0.157
0.327CysGln: 0.327 ± 0.157
0.0CysArg: 0.0 ± 0.0
1.308CysSer: 1.308 ± 0.526
1.308CysThr: 1.308 ± 0.526
0.327CysVal: 0.327 ± 0.157
0.0CysTrp: 0.0 ± 0.0
0.981CysTyr: 0.981 ± 0.572
0.0CysXaa: 0.0 ± 0.0
Asp
2.943AspAla: 2.943 ± 0.966
0.654AspCys: 0.654 ± 0.314
5.559AspAsp: 5.559 ± 0.872
3.924AspGlu: 3.924 ± 1.182
3.597AspPhe: 3.597 ± 0.34
2.943AspGly: 2.943 ± 0.749
0.981AspHis: 0.981 ± 0.451
3.597AspIle: 3.597 ± 0.466
5.559AspLys: 5.559 ± 0.872
5.559AspLeu: 5.559 ± 1.647
1.962AspMet: 1.962 ± 0.454
2.289AspAsn: 2.289 ± 0.552
0.981AspPro: 0.981 ± 0.572
1.962AspGln: 1.962 ± 0.569
0.654AspArg: 0.654 ± 0.314
3.597AspSer: 3.597 ± 0.34
3.27AspThr: 3.27 ± 0.79
4.905AspVal: 4.905 ± 1.695
0.327AspTrp: 0.327 ± 0.157
2.943AspTyr: 2.943 ± 1.44
0.0AspXaa: 0.0 ± 0.0
Glu
3.597GluAla: 3.597 ± 0.34
0.654GluCys: 0.654 ± 0.314
4.251GluAsp: 4.251 ± 0.659
8.175GluGlu: 8.175 ± 1.352
3.597GluPhe: 3.597 ± 1.726
2.616GluGly: 2.616 ± 0.674
1.308GluHis: 1.308 ± 0.394
6.54GluIle: 6.54 ± 2.484
5.559GluLys: 5.559 ± 2.112
9.483GluLeu: 9.483 ± 1.844
1.635GluMet: 1.635 ± 0.897
6.54GluAsn: 6.54 ± 0.714
1.962GluPro: 1.962 ± 0.569
1.308GluGln: 1.308 ± 0.628
2.943GluArg: 2.943 ± 3.151
5.232GluSer: 5.232 ± 1.226
2.943GluThr: 2.943 ± 0.874
3.27GluVal: 3.27 ± 1.406
0.981GluTrp: 0.981 ± 0.471
2.943GluTyr: 2.943 ± 0.807
0.0GluXaa: 0.0 ± 0.0
Phe
2.289PheAla: 2.289 ± 1.749
0.981PheCys: 0.981 ± 0.471
3.924PheAsp: 3.924 ± 1.883
5.232PheGlu: 5.232 ± 1.347
2.289PhePhe: 2.289 ± 1.099
1.962PheGly: 1.962 ± 1.144
1.635PheHis: 1.635 ± 0.395
2.616PheIle: 2.616 ± 1.255
4.578PheLys: 4.578 ± 1.335
6.54PheLeu: 6.54 ± 1.784
2.943PheMet: 2.943 ± 0.726
4.905PheAsn: 4.905 ± 0.95
2.616PhePro: 2.616 ± 0.898
2.289PheGln: 2.289 ± 0.649
2.616PheArg: 2.616 ± 0.898
3.27PheSer: 3.27 ± 1.004
1.635PheThr: 1.635 ± 1.49
3.924PheVal: 3.924 ± 0.488
0.0PheTrp: 0.0 ± 0.0
1.635PheTyr: 1.635 ± 0.395
0.0PheXaa: 0.0 ± 0.0
Gly
0.981GlyAla: 0.981 ± 0.572
1.308GlyCys: 1.308 ± 0.526
2.943GlyAsp: 2.943 ± 1.44
1.308GlyGlu: 1.308 ± 0.394
3.924GlyPhe: 3.924 ± 2.406
0.654GlyGly: 0.654 ± 0.549
0.0GlyHis: 0.0 ± 0.0
2.616GlyIle: 2.616 ± 1.255
3.597GlyLys: 3.597 ± 1.142
4.251GlyLeu: 4.251 ± 1.691
0.981GlyMet: 0.981 ± 0.451
2.289GlyAsn: 2.289 ± 1.088
0.654GlyPro: 0.654 ± 0.314
0.981GlyGln: 0.981 ± 0.572
1.308GlyArg: 1.308 ± 0.797
3.597GlySer: 3.597 ± 2.559
1.962GlyThr: 1.962 ± 0.903
1.308GlyVal: 1.308 ± 0.394
0.327GlyTrp: 0.327 ± 0.157
1.962GlyTyr: 1.962 ± 0.942
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.327HisCys: 0.327 ± 0.157
0.654HisAsp: 0.654 ± 0.549
2.616HisGlu: 2.616 ± 1.255
1.308HisPhe: 1.308 ± 0.394
0.0HisGly: 0.0 ± 0.0
0.654HisHis: 0.654 ± 0.314
0.654HisIle: 0.654 ± 0.314
1.308HisLys: 1.308 ± 0.628
2.943HisLeu: 2.943 ± 0.749
0.981HisMet: 0.981 ± 0.451
0.981HisAsn: 0.981 ± 0.471
0.327HisPro: 0.327 ± 0.157
0.327HisGln: 0.327 ± 0.157
0.327HisArg: 0.327 ± 0.157
1.308HisSer: 1.308 ± 0.797
1.308HisThr: 1.308 ± 0.526
0.981HisVal: 0.981 ± 0.471
0.0HisTrp: 0.0 ± 0.0
1.308HisTyr: 1.308 ± 0.628
0.0HisXaa: 0.0 ± 0.0
Ile
1.962IleAla: 1.962 ± 1.144
0.654IleCys: 0.654 ± 0.314
2.943IleAsp: 2.943 ± 0.807
8.175IleGlu: 8.175 ± 1.601
3.924IlePhe: 3.924 ± 1.283
2.616IleGly: 2.616 ± 1.594
0.981IleHis: 0.981 ± 0.471
7.521IleIle: 7.521 ± 2.2
7.194IleLys: 7.194 ± 1.359
4.905IleLeu: 4.905 ± 0.693
2.289IleMet: 2.289 ± 1.099
5.232IleAsn: 5.232 ± 0.468
1.962IlePro: 1.962 ± 0.491
1.962IleGln: 1.962 ± 0.454
2.289IleArg: 2.289 ± 1.05
6.867IleSer: 6.867 ± 1.617
4.251IleThr: 4.251 ± 0.999
4.578IleVal: 4.578 ± 0.795
1.308IleTrp: 1.308 ± 0.394
1.308IleTyr: 1.308 ± 0.526
0.0IleXaa: 0.0 ± 0.0
Lys
3.597LysAla: 3.597 ± 2.874
2.289LysCys: 2.289 ± 0.552
8.175LysAsp: 8.175 ± 1.274
5.886LysGlu: 5.886 ± 1.748
5.559LysPhe: 5.559 ± 0.606
5.559LysGly: 5.559 ± 1.647
0.981LysHis: 0.981 ± 0.572
9.483LysIle: 9.483 ± 0.597
8.502LysLys: 8.502 ± 1.267
10.464LysLeu: 10.464 ± 2.694
3.597LysMet: 3.597 ± 0.466
3.597LysAsn: 3.597 ± 1.093
1.308LysPro: 1.308 ± 0.628
4.251LysGln: 4.251 ± 0.659
2.616LysArg: 2.616 ± 0.674
5.886LysSer: 5.886 ± 1.173
4.905LysThr: 4.905 ± 1.183
5.232LysVal: 5.232 ± 0.414
0.981LysTrp: 0.981 ± 0.471
2.289LysTyr: 2.289 ± 1.216
0.0LysXaa: 0.0 ± 0.0
Leu
1.635LeuAla: 1.635 ± 1.218
1.962LeuCys: 1.962 ± 1.144
3.597LeuAsp: 3.597 ± 1.268
8.829LeuGlu: 8.829 ± 0.716
4.578LeuPhe: 4.578 ± 1.575
5.559LeuGly: 5.559 ± 1.623
0.981LeuHis: 0.981 ± 0.471
6.213LeuIle: 6.213 ± 1.078
11.118LeuLys: 11.118 ± 1.843
10.791LeuLeu: 10.791 ± 1.82
3.27LeuMet: 3.27 ± 0.79
6.867LeuAsn: 6.867 ± 1.205
4.578LeuPro: 4.578 ± 1.575
4.251LeuGln: 4.251 ± 1.496
4.251LeuArg: 4.251 ± 0.265
10.791LeuSer: 10.791 ± 3.072
6.867LeuThr: 6.867 ± 2.419
4.578LeuVal: 4.578 ± 1.542
0.327LeuTrp: 0.327 ± 0.157
2.289LeuTyr: 2.289 ± 0.552
0.0LeuXaa: 0.0 ± 0.0
Met
1.635MetAla: 1.635 ± 0.525
0.0MetCys: 0.0 ± 0.0
1.635MetAsp: 1.635 ± 0.993
0.981MetGlu: 0.981 ± 0.471
2.289MetPhe: 2.289 ± 1.099
0.327MetGly: 0.327 ± 0.157
0.654MetHis: 0.654 ± 0.314
4.251MetIle: 4.251 ± 0.265
3.27MetLys: 3.27 ± 0.205
0.981MetLeu: 0.981 ± 0.471
0.0MetMet: 0.0 ± 0.0
2.289MetAsn: 2.289 ± 0.832
0.981MetPro: 0.981 ± 0.451
0.327MetGln: 0.327 ± 0.157
0.981MetArg: 0.981 ± 0.451
3.924MetSer: 3.924 ± 1.182
1.308MetThr: 1.308 ± 0.526
0.981MetVal: 0.981 ± 0.471
0.0MetTrp: 0.0 ± 0.0
0.327MetTyr: 0.327 ± 0.67
0.0MetXaa: 0.0 ± 0.0
Asn
2.616AsnAla: 2.616 ± 1.053
1.308AsnCys: 1.308 ± 0.394
3.924AsnAsp: 3.924 ± 0.488
3.924AsnGlu: 3.924 ± 1.182
6.213AsnPhe: 6.213 ± 1.161
2.289AsnGly: 2.289 ± 0.552
1.635AsnHis: 1.635 ± 0.525
2.943AsnIle: 2.943 ± 1.717
4.578AsnLys: 4.578 ± 0.894
10.137AsnLeu: 10.137 ± 3.149
1.308AsnMet: 1.308 ± 0.628
4.251AsnAsn: 4.251 ± 0.64
1.962AsnPro: 1.962 ± 1.203
1.635AsnGln: 1.635 ± 0.395
0.981AsnArg: 0.981 ± 0.471
4.905AsnSer: 4.905 ± 0.95
2.616AsnThr: 2.616 ± 0.754
1.962AsnVal: 1.962 ± 0.903
0.654AsnTrp: 0.654 ± 0.549
4.251AsnTyr: 4.251 ± 0.64
0.0AsnXaa: 0.0 ± 0.0
Pro
1.635ProAla: 1.635 ± 0.643
0.654ProCys: 0.654 ± 0.549
1.308ProAsp: 1.308 ± 0.628
2.289ProGlu: 2.289 ± 1.088
1.635ProPhe: 1.635 ± 0.785
0.0ProGly: 0.0 ± 0.0
0.981ProHis: 0.981 ± 0.451
2.616ProIle: 2.616 ± 0.898
4.905ProLys: 4.905 ± 1.222
1.308ProLeu: 1.308 ± 0.394
0.654ProMet: 0.654 ± 0.314
0.654ProAsn: 0.654 ± 0.549
0.981ProPro: 0.981 ± 0.471
1.635ProGln: 1.635 ± 0.395
0.327ProArg: 0.327 ± 0.157
2.943ProSer: 2.943 ± 1.412
0.654ProThr: 0.654 ± 0.654
0.654ProVal: 0.654 ± 0.314
0.0ProTrp: 0.0 ± 0.0
0.981ProTyr: 0.981 ± 0.572
0.0ProXaa: 0.0 ± 0.0
Gln
0.981GlnAla: 0.981 ± 0.471
0.654GlnCys: 0.654 ± 0.654
1.962GlnAsp: 1.962 ± 0.569
2.943GlnGlu: 2.943 ± 0.773
0.981GlnPhe: 0.981 ± 0.471
2.289GlnGly: 2.289 ± 0.552
0.981GlnHis: 0.981 ± 0.471
3.27GlnIle: 3.27 ± 1.406
3.27GlnLys: 3.27 ± 0.205
4.251GlnLeu: 4.251 ± 1.211
0.327GlnMet: 0.327 ± 0.67
1.962GlnAsn: 1.962 ± 0.491
0.981GlnPro: 0.981 ± 0.471
0.0GlnGln: 0.0 ± 0.0
0.981GlnArg: 0.981 ± 0.572
3.597GlnSer: 3.597 ± 0.466
1.635GlnThr: 1.635 ± 0.785
2.289GlnVal: 2.289 ± 0.552
0.327GlnTrp: 0.327 ± 0.157
0.981GlnTyr: 0.981 ± 0.572
0.0GlnXaa: 0.0 ± 0.0
Arg
0.327ArgAla: 0.327 ± 0.67
0.0ArgCys: 0.0 ± 0.0
2.616ArgAsp: 2.616 ± 0.788
3.924ArgGlu: 3.924 ± 1.135
1.308ArgPhe: 1.308 ± 1.883
0.981ArgGly: 0.981 ± 0.572
0.654ArgHis: 0.654 ± 0.549
1.962ArgIle: 1.962 ± 0.491
4.251ArgLys: 4.251 ± 0.831
2.289ArgLeu: 2.289 ± 1.099
0.327ArgMet: 0.327 ± 0.157
2.616ArgAsn: 2.616 ± 0.207
0.654ArgPro: 0.654 ± 0.549
2.616ArgGln: 2.616 ± 0.898
0.981ArgArg: 0.981 ± 0.572
2.289ArgSer: 2.289 ± 1.216
1.635ArgThr: 1.635 ± 0.993
2.289ArgVal: 2.289 ± 0.832
0.0ArgTrp: 0.0 ± 0.0
1.308ArgTyr: 1.308 ± 0.628
0.0ArgXaa: 0.0 ± 0.0
Ser
1.308SerAla: 1.308 ± 0.526
1.635SerCys: 1.635 ± 0.525
3.597SerAsp: 3.597 ± 3.334
6.213SerGlu: 6.213 ± 1.555
4.905SerPhe: 4.905 ± 0.544
2.943SerGly: 2.943 ± 1.44
2.289SerHis: 2.289 ± 0.649
5.559SerIle: 5.559 ± 0.311
7.521SerLys: 7.521 ± 1.015
9.483SerLeu: 9.483 ± 1.027
2.616SerMet: 2.616 ± 0.87
5.559SerAsn: 5.559 ± 1.624
1.635SerPro: 1.635 ± 0.395
4.251SerGln: 4.251 ± 0.831
4.251SerArg: 4.251 ± 0.999
15.697SerSer: 15.697 ± 2.743
6.54SerThr: 6.54 ± 0.882
3.597SerVal: 3.597 ± 0.765
0.654SerTrp: 0.654 ± 0.314
4.578SerTyr: 4.578 ± 1.575
0.0SerXaa: 0.0 ± 0.0
Thr
1.308ThrAla: 1.308 ± 1.307
0.981ThrCys: 0.981 ± 0.471
2.289ThrAsp: 2.289 ± 0.649
2.616ThrGlu: 2.616 ± 0.674
3.924ThrPhe: 3.924 ± 0.981
1.308ThrGly: 1.308 ± 1.307
0.981ThrHis: 0.981 ± 0.471
4.251ThrIle: 4.251 ± 1.211
4.251ThrLys: 4.251 ± 0.265
5.232ThrLeu: 5.232 ± 1.443
1.308ThrMet: 1.308 ± 0.526
3.27ThrAsn: 3.27 ± 1.966
0.654ThrPro: 0.654 ± 0.314
2.289ThrGln: 2.289 ± 1.099
2.943ThrArg: 2.943 ± 2.122
4.905ThrSer: 4.905 ± 0.544
2.616ThrThr: 2.616 ± 0.674
4.251ThrVal: 4.251 ± 1.496
0.0ThrTrp: 0.0 ± 0.0
1.308ThrTyr: 1.308 ± 0.394
0.0ThrXaa: 0.0 ± 0.0
Val
2.616ValAla: 2.616 ± 1.594
1.635ValCys: 1.635 ± 0.785
1.962ValAsp: 1.962 ± 0.454
3.597ValGlu: 3.597 ± 1.726
1.962ValPhe: 1.962 ± 0.569
2.289ValGly: 2.289 ± 0.832
0.981ValHis: 0.981 ± 0.451
1.308ValIle: 1.308 ± 0.628
6.213ValLys: 6.213 ± 0.9
4.251ValLeu: 4.251 ± 0.265
0.654ValMet: 0.654 ± 0.314
3.924ValAsn: 3.924 ± 0.345
2.289ValPro: 2.289 ± 0.552
2.289ValGln: 2.289 ± 0.552
2.943ValArg: 2.943 ± 0.807
5.559ValSer: 5.559 ± 0.658
2.616ValThr: 2.616 ± 1.053
3.597ValVal: 3.597 ± 1.142
1.308ValTrp: 1.308 ± 0.526
1.635ValTyr: 1.635 ± 0.993
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.327TrpAsp: 0.327 ± 0.157
0.654TrpGlu: 0.654 ± 0.314
0.654TrpPhe: 0.654 ± 0.314
0.981TrpGly: 0.981 ± 0.471
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.981TrpLys: 0.981 ± 0.471
1.308TrpLeu: 1.308 ± 0.628
0.327TrpMet: 0.327 ± 0.157
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.654TrpSer: 0.654 ± 0.654
0.327TrpThr: 0.327 ± 0.67
0.981TrpVal: 0.981 ± 0.451
0.327TrpTrp: 0.327 ± 0.157
0.654TrpTyr: 0.654 ± 0.654
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.308TyrAla: 1.308 ± 1.307
0.654TyrCys: 0.654 ± 0.654
2.943TyrAsp: 2.943 ± 0.749
1.962TyrGlu: 1.962 ± 0.454
1.308TyrPhe: 1.308 ± 0.526
1.308TyrGly: 1.308 ± 0.526
0.327TyrHis: 0.327 ± 0.157
2.616TyrIle: 2.616 ± 1.255
2.616TyrLys: 2.616 ± 0.788
2.616TyrLeu: 2.616 ± 1.788
1.308TyrMet: 1.308 ± 0.797
3.597TyrAsn: 3.597 ± 1.142
1.308TyrPro: 1.308 ± 0.394
1.635TyrGln: 1.635 ± 0.785
0.981TyrArg: 0.981 ± 0.952
5.232TyrSer: 5.232 ± 2.224
0.981TyrThr: 0.981 ± 0.451
3.27TyrVal: 3.27 ± 1.004
0.327TyrTrp: 0.327 ± 0.157
1.962TyrTyr: 1.962 ± 0.454
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3059 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski