Amino acid dipepetide frequency for Amylibacter kogurei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.77AlaAla: 11.77 ± 0.158	0.988AlaCys: 0.988 ± 0.037	6.417AlaAsp: 6.417 ± 0.1	5.722AlaGlu: 5.722 ± 0.1	4.111AlaPhe: 4.111 ± 0.07	8.691AlaGly: 8.691 ± 0.127	2.076AlaHis: 2.076 ± 0.047	6.767AlaIle: 6.767 ± 0.099	5.43AlaLys: 5.43 ± 0.105	10.703AlaLeu: 10.703 ± 0.122	3.631AlaMet: 3.631 ± 0.067	3.777AlaAsn: 3.777 ± 0.062	4.342AlaPro: 4.342 ± 0.071	4.528AlaGln: 4.528 ± 0.08	5.679AlaArg: 5.679 ± 0.097	5.542AlaSer: 5.542 ± 0.08	5.545AlaThr: 5.545 ± 0.099	6.777AlaVal: 6.777 ± 0.095	1.145AlaTrp: 1.145 ± 0.038	2.455AlaTyr: 2.455 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.154CysAla: 1.154 ± 0.035	0.104CysCys: 0.104 ± 0.012	0.692CysAsp: 0.692 ± 0.03	0.612CysGlu: 0.612 ± 0.026	0.434CysPhe: 0.434 ± 0.024	0.919CysGly: 0.919 ± 0.032	0.271CysHis: 0.271 ± 0.016	0.565CysIle: 0.565 ± 0.027	0.317CysLys: 0.317 ± 0.02	0.83CysLeu: 0.83 ± 0.031	0.205CysMet: 0.205 ± 0.015	0.288CysAsn: 0.288 ± 0.017	0.475CysPro: 0.475 ± 0.024	0.254CysGln: 0.254 ± 0.016	0.42CysArg: 0.42 ± 0.024	0.53CysSer: 0.53 ± 0.027	0.509CysThr: 0.509 ± 0.025	0.732CysVal: 0.732 ± 0.029	0.112CysTrp: 0.112 ± 0.011	0.241CysTyr: 0.241 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.331AspAla: 7.331 ± 0.122	0.555AspCys: 0.555 ± 0.023	4.239AspAsp: 4.239 ± 0.143	3.85AspGlu: 3.85 ± 0.073	2.527AspPhe: 2.527 ± 0.054	5.667AspGly: 5.667 ± 0.127	1.562AspHis: 1.562 ± 0.043	4.069AspIle: 4.069 ± 0.076	2.391AspLys: 2.391 ± 0.051	5.848AspLeu: 5.848 ± 0.089	1.957AspMet: 1.957 ± 0.053	1.905AspAsn: 1.905 ± 0.056	2.939AspPro: 2.939 ± 0.059	2.392AspGln: 2.392 ± 0.057	3.381AspArg: 3.381 ± 0.067	2.393AspSer: 2.393 ± 0.078	3.297AspThr: 3.297 ± 0.097	4.736AspVal: 4.736 ± 0.078	1.064AspTrp: 1.064 ± 0.035	1.695AspTyr: 1.695 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	4.792GluAla: 4.792 ± 0.105	0.453GluCys: 0.453 ± 0.022	2.728GluAsp: 2.728 ± 0.061	2.845GluGlu: 2.845 ± 0.071	2.331GluPhe: 2.331 ± 0.046	3.324GluGly: 3.324 ± 0.066	1.285GluHis: 1.285 ± 0.045	4.327GluIle: 4.327 ± 0.072	2.91GluLys: 2.91 ± 0.059	5.381GluLeu: 5.381 ± 0.089	1.899GluMet: 1.899 ± 0.042	2.795GluAsn: 2.795 ± 0.059	2.275GluPro: 2.275 ± 0.059	2.277GluGln: 2.277 ± 0.051	3.427GluArg: 3.427 ± 0.076	2.478GluSer: 2.478 ± 0.05	4.139GluThr: 4.139 ± 0.073	3.309GluVal: 3.309 ± 0.064	0.736GluTrp: 0.736 ± 0.027	1.387GluTyr: 1.387 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	4.696PheAla: 4.696 ± 0.074	0.551PheCys: 0.551 ± 0.026	3.233PheAsp: 3.233 ± 0.067	2.434PheGlu: 2.434 ± 0.053	1.68PhePhe: 1.68 ± 0.058	3.946PheGly: 3.946 ± 0.077	0.816PheHis: 0.816 ± 0.03	2.393PheIle: 2.393 ± 0.053	1.477PheLys: 1.477 ± 0.037	3.593PheLeu: 3.593 ± 0.072	1.062PheMet: 1.062 ± 0.034	1.539PheAsn: 1.539 ± 0.043	1.569PhePro: 1.569 ± 0.039	1.326PheGln: 1.326 ± 0.037	1.844PheArg: 1.844 ± 0.044	2.608PheSer: 2.608 ± 0.055	2.255PheThr: 2.255 ± 0.052	2.949PheVal: 2.949 ± 0.063	0.648PheTrp: 0.648 ± 0.029	1.113PheTyr: 1.113 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	8.551GlyAla: 8.551 ± 0.107	0.837GlyCys: 0.837 ± 0.035	4.942GlyAsp: 4.942 ± 0.134	4.54GlyGlu: 4.54 ± 0.07	3.769GlyPhe: 3.769 ± 0.07	6.749GlyGly: 6.749 ± 0.148	1.712GlyHis: 1.712 ± 0.043	4.851GlyIle: 4.851 ± 0.084	3.868GlyLys: 3.868 ± 0.062	7.751GlyLeu: 7.751 ± 0.117	2.636GlyMet: 2.636 ± 0.061	2.705GlyAsn: 2.705 ± 0.084	2.565GlyPro: 2.565 ± 0.051	2.9GlyGln: 2.9 ± 0.062	4.195GlyArg: 4.195 ± 0.073	3.99GlySer: 3.99 ± 0.074	4.032GlyThr: 4.032 ± 0.076	6.327GlyVal: 6.327 ± 0.091	1.181GlyTrp: 1.181 ± 0.038	2.406GlyTyr: 2.406 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.123HisAla: 2.123 ± 0.046	0.245HisCys: 0.245 ± 0.016	1.384HisAsp: 1.384 ± 0.041	0.989HisGlu: 0.989 ± 0.033	0.956HisPhe: 0.956 ± 0.033	1.862HisGly: 1.862 ± 0.05	0.664HisHis: 0.664 ± 0.029	1.277HisIle: 1.277 ± 0.036	0.753HisLys: 0.753 ± 0.027	2.014HisLeu: 2.014 ± 0.045	0.634HisMet: 0.634 ± 0.026	0.691HisAsn: 0.691 ± 0.029	1.265HisPro: 1.265 ± 0.043	0.705HisGln: 0.705 ± 0.028	1.197HisArg: 1.197 ± 0.041	1.059HisSer: 1.059 ± 0.032	0.905HisThr: 0.905 ± 0.031	1.463HisVal: 1.463 ± 0.038	0.302HisTrp: 0.302 ± 0.018	0.589HisTyr: 0.589 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	7.776IleAla: 7.776 ± 0.099	0.829IleCys: 0.829 ± 0.029	4.315IleAsp: 4.315 ± 0.1	3.771IleGlu: 3.771 ± 0.07	2.461IlePhe: 2.461 ± 0.066	5.506IleGly: 5.506 ± 0.093	1.154IleHis: 1.154 ± 0.036	3.527IleIle: 3.527 ± 0.063	2.648IleLys: 2.648 ± 0.058	5.643IleLeu: 5.643 ± 0.087	1.439IleMet: 1.439 ± 0.045	2.164IleAsn: 2.164 ± 0.048	2.791IlePro: 2.791 ± 0.063	1.685IleGln: 1.685 ± 0.046	2.91IleArg: 2.91 ± 0.057	4.116IleSer: 4.116 ± 0.071	3.886IleThr: 3.886 ± 0.074	4.422IleVal: 4.422 ± 0.072	0.876IleTrp: 0.876 ± 0.034	1.6IleTyr: 1.6 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	3.934LysAla: 3.934 ± 0.08	0.303LysCys: 0.303 ± 0.019	2.528LysAsp: 2.528 ± 0.055	2.086LysGlu: 2.086 ± 0.055	1.716LysPhe: 1.716 ± 0.048	3.164LysGly: 3.164 ± 0.07	1.008LysHis: 1.008 ± 0.036	3.039LysIle: 3.039 ± 0.058	2.138LysLys: 2.138 ± 0.061	4.185LysLeu: 4.185 ± 0.07	1.373LysMet: 1.373 ± 0.042	1.847LysAsn: 1.847 ± 0.043	2.324LysPro: 2.324 ± 0.067	1.539LysGln: 1.539 ± 0.044	2.86LysArg: 2.86 ± 0.066	3.359LysSer: 3.359 ± 0.065	3.075LysThr: 3.075 ± 0.067	2.597LysVal: 2.597 ± 0.057	0.555LysTrp: 0.555 ± 0.023	1.09LysTyr: 1.09 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.297LeuAla: 10.297 ± 0.131	1.001LeuCys: 1.001 ± 0.033	5.884LeuAsp: 5.884 ± 0.09	4.869LeuGlu: 4.869 ± 0.086	3.845LeuPhe: 3.845 ± 0.082	7.72LeuGly: 7.72 ± 0.122	1.809LeuHis: 1.809 ± 0.047	6.008LeuIle: 6.008 ± 0.094	3.885LeuLys: 3.885 ± 0.074	7.901LeuLeu: 7.901 ± 0.136	2.575LeuMet: 2.575 ± 0.06	3.672LeuAsn: 3.672 ± 0.065	4.568LeuPro: 4.568 ± 0.076	3.024LeuGln: 3.024 ± 0.062	5.802LeuArg: 5.802 ± 0.094	6.384LeuSer: 6.384 ± 0.091	5.194LeuThr: 5.194 ± 0.089	5.984LeuVal: 5.984 ± 0.098	1.069LeuTrp: 1.069 ± 0.04	1.969LeuTyr: 1.969 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.361MetAla: 3.361 ± 0.071	0.231MetCys: 0.231 ± 0.015	1.674MetAsp: 1.674 ± 0.043	1.426MetGlu: 1.426 ± 0.04	1.064MetPhe: 1.064 ± 0.038	2.399MetGly: 2.399 ± 0.063	0.529MetHis: 0.529 ± 0.025	1.922MetIle: 1.922 ± 0.051	1.416MetLys: 1.416 ± 0.038	2.749MetLeu: 2.749 ± 0.053	0.855MetMet: 0.855 ± 0.029	1.265MetAsn: 1.265 ± 0.034	1.436MetPro: 1.436 ± 0.047	1.056MetGln: 1.056 ± 0.033	1.812MetArg: 1.812 ± 0.045	1.854MetSer: 1.854 ± 0.045	1.958MetThr: 1.958 ± 0.044	1.971MetVal: 1.971 ± 0.047	0.262MetTrp: 0.262 ± 0.016	0.467MetTyr: 0.467 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.41AsnAla: 4.41 ± 0.069	0.37AsnCys: 0.37 ± 0.019	2.41AsnAsp: 2.41 ± 0.094	1.763AsnGlu: 1.763 ± 0.044	1.449AsnPhe: 1.449 ± 0.037	3.359AsnGly: 3.359 ± 0.068	0.796AsnHis: 0.796 ± 0.031	2.423AsnIle: 2.423 ± 0.061	1.447AsnLys: 1.447 ± 0.038	3.534AsnLeu: 3.534 ± 0.061	1.034AsnMet: 1.034 ± 0.033	1.308AsnAsn: 1.308 ± 0.042	2.22AsnPro: 2.22 ± 0.051	1.21AsnGln: 1.21 ± 0.04	1.938AsnArg: 1.938 ± 0.05	1.902AsnSer: 1.902 ± 0.051	2.049AsnThr: 2.049 ± 0.055	2.564AsnVal: 2.564 ± 0.054	0.621AsnTrp: 0.621 ± 0.028	0.947AsnTyr: 0.947 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.185ProAla: 4.185 ± 0.08	0.318ProCys: 0.318 ± 0.02	3.445ProAsp: 3.445 ± 0.063	3.271ProGlu: 3.271 ± 0.063	1.95ProPhe: 1.95 ± 0.052	2.297ProGly: 2.297 ± 0.049	0.982ProHis: 0.982 ± 0.035	2.869ProIle: 2.869 ± 0.06	2.304ProLys: 2.304 ± 0.055	3.799ProLeu: 3.799 ± 0.064	1.328ProMet: 1.328 ± 0.04	2.06ProAsn: 2.06 ± 0.054	1.564ProPro: 1.564 ± 0.043	1.416ProGln: 1.416 ± 0.043	2.061ProArg: 2.061 ± 0.046	2.668ProSer: 2.668 ± 0.063	2.6ProThr: 2.6 ± 0.059	3.443ProVal: 3.443 ± 0.056	0.531ProTrp: 0.531 ± 0.025	1.153ProTyr: 1.153 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.381GlnAla: 3.381 ± 0.062	0.254GlnCys: 0.254 ± 0.02	1.902GlnAsp: 1.902 ± 0.048	1.761GlnGlu: 1.761 ± 0.048	1.413GlnPhe: 1.413 ± 0.038	2.483GlnGly: 2.483 ± 0.051	0.689GlnHis: 0.689 ± 0.027	2.517GlnIle: 2.517 ± 0.052	1.769GlnLys: 1.769 ± 0.046	3.032GlnLeu: 3.032 ± 0.059	1.219GlnMet: 1.219 ± 0.038	1.653GlnAsn: 1.653 ± 0.051	1.39GlnPro: 1.39 ± 0.039	1.262GlnGln: 1.262 ± 0.048	2.083GlnArg: 2.083 ± 0.055	2.436GlnSer: 2.436 ± 0.058	2.247GlnThr: 2.247 ± 0.048	2.282GlnVal: 2.282 ± 0.05	0.446GlnTrp: 0.446 ± 0.022	0.82GlnTyr: 0.82 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	5.743ArgAla: 5.743 ± 0.085	0.468ArgCys: 0.468 ± 0.022	3.699ArgAsp: 3.699 ± 0.074	3.106ArgGlu: 3.106 ± 0.063	2.365ArgPhe: 2.365 ± 0.057	3.718ArgGly: 3.718 ± 0.066	1.155ArgHis: 1.155 ± 0.037	3.441ArgIle: 3.441 ± 0.068	2.755ArgLys: 2.755 ± 0.06	5.21ArgLeu: 5.21 ± 0.095	1.707ArgMet: 1.707 ± 0.048	2.094ArgAsn: 2.094 ± 0.053	2.266ArgPro: 2.266 ± 0.053	1.885ArgGln: 1.885 ± 0.045	3.137ArgArg: 3.137 ± 0.062	2.747ArgSer: 2.747 ± 0.058	2.411ArgThr: 2.411 ± 0.05	3.936ArgVal: 3.936 ± 0.065	0.705ArgTrp: 0.705 ± 0.033	1.376ArgTyr: 1.376 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.929SerAla: 5.929 ± 0.082	0.463SerCys: 0.463 ± 0.025	3.878SerAsp: 3.878 ± 0.077	3.231SerGlu: 3.231 ± 0.064	2.518SerPhe: 2.518 ± 0.055	5.341SerGly: 5.341 ± 0.083	1.131SerHis: 1.131 ± 0.037	3.284SerIle: 3.284 ± 0.062	2.479SerLys: 2.479 ± 0.056	5.104SerLeu: 5.104 ± 0.086	1.554SerMet: 1.554 ± 0.046	2.16SerAsn: 2.16 ± 0.054	2.482SerPro: 2.482 ± 0.049	1.923SerGln: 1.923 ± 0.052	2.73SerArg: 2.73 ± 0.056	2.846SerSer: 2.846 ± 0.063	2.854SerThr: 2.854 ± 0.059	4.254SerVal: 4.254 ± 0.066	0.701SerTrp: 0.701 ± 0.031	1.387SerTyr: 1.387 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.624ThrAla: 5.624 ± 0.091	0.564ThrCys: 0.564 ± 0.028	3.4ThrAsp: 3.4 ± 0.074	2.631ThrGlu: 2.631 ± 0.055	2.174ThrPhe: 2.174 ± 0.057	4.986ThrGly: 4.986 ± 0.095	1.185ThrHis: 1.185 ± 0.034	3.567ThrIle: 3.567 ± 0.086	2.458ThrLys: 2.458 ± 0.056	5.766ThrLeu: 5.766 ± 0.084	1.428ThrMet: 1.428 ± 0.042	1.962ThrAsn: 1.962 ± 0.046	3.404ThrPro: 3.404 ± 0.066	1.997ThrGln: 1.997 ± 0.054	2.946ThrArg: 2.946 ± 0.062	3.012ThrSer: 3.012 ± 0.055	3.164ThrThr: 3.164 ± 0.081	3.932ThrVal: 3.932 ± 0.075	0.642ThrTrp: 0.642 ± 0.032	1.379ThrTyr: 1.379 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	7.263ValAla: 7.263 ± 0.1	0.712ValCys: 0.712 ± 0.03	4.478ValAsp: 4.478 ± 0.075	4.259ValGlu: 4.259 ± 0.074	3.139ValPhe: 3.139 ± 0.064	5.259ValGly: 5.259 ± 0.079	1.299ValHis: 1.299 ± 0.039	4.696ValIle: 4.696 ± 0.084	2.867ValLys: 2.867 ± 0.06	6.591ValLeu: 6.591 ± 0.105	2.212ValMet: 2.212 ± 0.053	2.513ValAsn: 2.513 ± 0.057	2.758ValPro: 2.758 ± 0.048	2.168ValGln: 2.168 ± 0.044	3.144ValArg: 3.144 ± 0.063	4.257ValSer: 4.257 ± 0.074	4.194ValThr: 4.194 ± 0.088	5.312ValVal: 5.312 ± 0.09	0.798ValTrp: 0.798 ± 0.03	1.596ValTyr: 1.596 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.177TrpAla: 1.177 ± 0.042	0.123TrpCys: 0.123 ± 0.012	0.805TrpAsp: 0.805 ± 0.032	0.609TrpGlu: 0.609 ± 0.026	0.638TrpPhe: 0.638 ± 0.025	0.933TrpGly: 0.933 ± 0.032	0.331TrpHis: 0.331 ± 0.02	0.73TrpIle: 0.73 ± 0.031	0.542TrpLys: 0.542 ± 0.028	1.413TrpLeu: 1.413 ± 0.045	0.412TrpMet: 0.412 ± 0.023	0.501TrpAsn: 0.501 ± 0.022	0.573TrpPro: 0.573 ± 0.027	0.56TrpGln: 0.56 ± 0.026	0.918TrpArg: 0.918 ± 0.037	0.717TrpSer: 0.717 ± 0.029	0.599TrpThr: 0.599 ± 0.03	0.911TrpVal: 0.911 ± 0.034	0.215TrpTrp: 0.215 ± 0.016	0.298TrpTyr: 0.298 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.6TyrAla: 2.6 ± 0.046	0.296TyrCys: 0.296 ± 0.018	1.744TyrAsp: 1.744 ± 0.042	1.324TyrGlu: 1.324 ± 0.042	1.193TyrPhe: 1.193 ± 0.039	2.181TyrGly: 2.181 ± 0.056	0.625TyrHis: 0.625 ± 0.028	1.247TyrIle: 1.247 ± 0.036	0.869TyrLys: 0.869 ± 0.029	2.415TyrLeu: 2.415 ± 0.055	0.543TyrMet: 0.543 ± 0.025	0.854TyrAsn: 0.854 ± 0.029	1.038TyrPro: 1.038 ± 0.035	0.932TyrGln: 0.932 ± 0.032	1.441TyrArg: 1.441 ± 0.041	1.35TyrSer: 1.35 ± 0.035	1.306TyrThr: 1.306 ± 0.045	1.612TyrVal: 1.612 ± 0.041	0.397TyrTrp: 0.397 ± 0.023	0.699TyrTyr: 0.699 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2837 proteins (911759 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---