Hepatitis C virus genotype 1a (isolate H77) (HCV)
Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes; Amarillovirales; Flaviviridae; Hepacivirus; Hepacivirus C; Hepatitis C virus genotype 1; Hepatitis C virus subtype 1a
Average proteome isoelectric point is 8.35
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Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>sp|P27958|POLG_HCV77 Genome polyprotein OS=Hepatitis C virus genotype 1a (isolate H77) OX=63746 PE=1 SV=3
MM1 pKa = 7.02STNPKK6 pKa = 8.89PQRR9 pKa = 11.84KK10 pKa = 6.64TKK12 pKa = 10.42RR13 pKa = 11.84NTNRR17 pKa = 11.84RR18 pKa = 11.84PQDD21 pKa = 3.19VKK23 pKa = 11.12FPGGGQIVGGVYY35 pKa = 10.66LLPRR39 pKa = 11.84RR40 pKa = 11.84GPRR43 pKa = 11.84LGVRR47 pKa = 11.84ATRR50 pKa = 11.84KK51 pKa = 7.58TSEE54 pKa = 3.85RR55 pKa = 11.84SQPRR59 pKa = 11.84GRR61 pKa = 11.84RR62 pKa = 11.84QPIPKK67 pKa = 9.59ARR69 pKa = 11.84RR70 pKa = 11.84PEE72 pKa = 3.84GRR74 pKa = 11.84TWAQPGYY81 pKa = 9.32PWPLYY86 pKa = 10.66GNEE89 pKa = 4.09GCGWAGWLLSPRR101 pKa = 11.84GSRR104 pKa = 11.84PSWGPTDD111 pKa = 3.29PRR113 pKa = 11.84RR114 pKa = 11.84RR115 pKa = 11.84SRR117 pKa = 11.84NLGKK121 pKa = 10.85VIDD124 pKa = 3.97TLTCGFADD132 pKa = 3.75LMGYY136 pKa = 9.34IPLVGAPLGGAARR149 pKa = 11.84ALAHH153 pKa = 5.78GVRR156 pKa = 11.84VLEE159 pKa = 5.04DD160 pKa = 3.44GVNYY164 pKa = 8.67ATGNLPGCSFSIFLLALLSCLTVPASAYY192 pKa = 7.58QVRR195 pKa = 11.84NSSGLYY201 pKa = 10.01HH202 pKa = 5.77VTNDD206 pKa = 3.94CPNSSVVYY214 pKa = 9.19EE215 pKa = 4.02AADD218 pKa = 4.68AILHH222 pKa = 5.76TPGCVPCVRR231 pKa = 11.84EE232 pKa = 4.55GNASRR237 pKa = 11.84CWVAVTPTVATRR249 pKa = 11.84DD250 pKa = 3.51GKK252 pKa = 11.25LPTTQLRR259 pKa = 11.84RR260 pKa = 11.84HH261 pKa = 6.37IDD263 pKa = 3.6LLVGSATLCSALYY276 pKa = 10.88VGDD279 pKa = 3.7LCGSVFLVGQLFTFSPRR296 pKa = 11.84HH297 pKa = 5.22HH298 pKa = 6.95WTTQDD303 pKa = 4.11CNCSIYY309 pKa = 9.95PGHH312 pKa = 6.19ITGHH316 pKa = 5.05RR317 pKa = 11.84MAWNMMMNWSPTAALVVAQLLRR339 pKa = 11.84IPQAIMDD346 pKa = 4.91MIAGAHH352 pKa = 5.67WGVLAGIKK360 pKa = 9.59YY361 pKa = 10.47FSMVGNWAKK370 pKa = 10.94VLVVLLLFAGVDD382 pKa = 3.57AEE384 pKa = 4.48THH386 pKa = 4.24VTGGNAGRR394 pKa = 11.84TTAGLVGLLTPGAKK408 pKa = 9.75QNIQLINTNGSWHH421 pKa = 6.65INSTALNCNEE431 pKa = 4.19SLNTGWLAGLFYY443 pKa = 9.73QHH445 pKa = 6.89KK446 pKa = 9.47FNSSGCPEE454 pKa = 4.06RR455 pKa = 11.84LASCRR460 pKa = 11.84RR461 pKa = 11.84LTDD464 pKa = 4.35FAQGWGPISYY474 pKa = 10.96ANGSGLDD481 pKa = 3.41EE482 pKa = 5.9RR483 pKa = 11.84PYY485 pKa = 10.22CWHH488 pKa = 6.35YY489 pKa = 10.29PPRR492 pKa = 11.84PCGIVPAKK500 pKa = 9.97SVCGPVYY507 pKa = 10.55CFTPSPVVVGTTDD520 pKa = 3.09RR521 pKa = 11.84SGAPTYY527 pKa = 11.0SWGANDD533 pKa = 3.4TDD535 pKa = 4.23VFVLNNTRR543 pKa = 11.84PPLGNWFGCTWMNSTGFTKK562 pKa = 10.5VCGAPPCVIGGVGNNTLLCPTDD584 pKa = 3.81CFRR587 pKa = 11.84KK588 pKa = 10.09YY589 pKa = 10.54PEE591 pKa = 4.06ATYY594 pKa = 10.48SRR596 pKa = 11.84CGSGPRR602 pKa = 11.84ITPRR606 pKa = 11.84CMVDD610 pKa = 2.96YY611 pKa = 9.47PYY613 pKa = 11.11RR614 pKa = 11.84LWHH617 pKa = 5.87YY618 pKa = 9.2PCTINYY624 pKa = 7.46TIFKK628 pKa = 9.44VRR630 pKa = 11.84MYY632 pKa = 10.87VGGVEE637 pKa = 4.23HH638 pKa = 7.17RR639 pKa = 11.84LEE641 pKa = 4.47AACNWTRR648 pKa = 11.84GEE650 pKa = 4.08RR651 pKa = 11.84CDD653 pKa = 5.26LEE655 pKa = 5.56DD656 pKa = 4.43RR657 pKa = 11.84DD658 pKa = 4.2RR659 pKa = 11.84SEE661 pKa = 5.24LSPLLLSTTQWQVLPCSFTTLPALSTGLIHH691 pKa = 6.97LHH693 pKa = 5.11QNIVDD698 pKa = 3.63VQYY701 pKa = 11.06LYY703 pKa = 11.42GVGSSIASWAIKK715 pKa = 9.15WEE717 pKa = 4.14YY718 pKa = 10.9VVLLFLLLADD728 pKa = 4.95ARR730 pKa = 11.84VCSCLWMMLLISQAEE745 pKa = 3.93AALEE749 pKa = 3.82NLVILNAASLAGTHH763 pKa = 6.1GLVSFLVFFCFAWYY777 pKa = 10.26LKK779 pKa = 10.06GRR781 pKa = 11.84WVPGAVYY788 pKa = 10.37ALYY791 pKa = 10.84GMWPLLLLLLALPQRR806 pKa = 11.84AYY808 pKa = 10.83ALDD811 pKa = 3.8TEE813 pKa = 4.98VAASCGGVVLVGLMALTLSPYY834 pKa = 8.32YY835 pKa = 10.31KK836 pKa = 10.1RR837 pKa = 11.84YY838 pKa = 10.03ISWCMWWLQYY848 pKa = 11.18FLTRR852 pKa = 11.84VEE854 pKa = 4.29AQLHH858 pKa = 4.93VWVPPLNVRR867 pKa = 11.84GGRR870 pKa = 11.84DD871 pKa = 3.28AVILLTCVVHH881 pKa = 6.24PALVFDD887 pKa = 3.65ITKK890 pKa = 10.55LLLAIFGPLWILQASLLKK908 pKa = 9.99VPYY911 pKa = 9.43FVRR914 pKa = 11.84VQGLLRR920 pKa = 11.84ICALARR926 pKa = 11.84KK927 pKa = 8.7IAGGHH932 pKa = 4.48YY933 pKa = 9.9VQMAIIKK940 pKa = 10.04LGALTGTCVYY950 pKa = 10.98NHH952 pKa = 7.36LAPLRR957 pKa = 11.84DD958 pKa = 3.39WAHH961 pKa = 5.92NGLRR965 pKa = 11.84DD966 pKa = 3.47LAVAVEE972 pKa = 4.1PVVFSRR978 pKa = 11.84MEE980 pKa = 4.01TKK982 pKa = 10.85LITWGADD989 pKa = 2.86TAACGDD995 pKa = 4.67IINGLPVSARR1005 pKa = 11.84RR1006 pKa = 11.84GQEE1009 pKa = 3.59ILLGPADD1016 pKa = 3.85GMVSKK1021 pKa = 10.42GWRR1024 pKa = 11.84LLAPITAYY1032 pKa = 10.28AQQTRR1037 pKa = 11.84GLLGCIITSLTGRR1050 pKa = 11.84DD1051 pKa = 3.34KK1052 pKa = 11.42NQVEE1056 pKa = 4.54GEE1058 pKa = 4.27VQIVSTATQTFLATCINGVCWTVYY1082 pKa = 10.09HH1083 pKa = 6.4GAGTRR1088 pKa = 11.84TIASPKK1094 pKa = 9.79GPVIQTYY1101 pKa = 9.49TNVDD1105 pKa = 3.03QDD1107 pKa = 4.21LVGWPAPQGSRR1118 pKa = 11.84SLTPCTCGSSDD1129 pKa = 3.64LYY1131 pKa = 11.23LVTRR1135 pKa = 11.84HH1136 pKa = 6.28ADD1138 pKa = 3.45VIPVRR1143 pKa = 11.84RR1144 pKa = 11.84RR1145 pKa = 11.84GDD1147 pKa = 3.24SRR1149 pKa = 11.84GSLLSPRR1156 pKa = 11.84PISYY1160 pKa = 10.76LKK1162 pKa = 10.52GSSGGPLLCPTGHH1175 pKa = 6.91AVGLFRR1181 pKa = 11.84AAVCTRR1187 pKa = 11.84GVAKK1191 pKa = 10.32AVDD1194 pKa = 4.84FIPVEE1199 pKa = 4.0NLEE1202 pKa = 4.23TTMRR1206 pKa = 11.84SPVFTDD1212 pKa = 3.2NSSPPAVPQSFQVAHH1227 pKa = 6.25LHH1229 pKa = 6.36APTGSGKK1236 pKa = 7.57STKK1239 pKa = 10.21VPAAYY1244 pKa = 9.45AAKK1247 pKa = 9.7GYY1249 pKa = 10.15KK1250 pKa = 9.95VLVLNPSVAATLGFGAYY1267 pKa = 8.02MSKK1270 pKa = 10.38AHH1272 pKa = 6.52GVDD1275 pKa = 3.36PNIRR1279 pKa = 11.84TGVRR1283 pKa = 11.84TITTGSPITYY1293 pKa = 8.3STYY1296 pKa = 11.23GKK1298 pKa = 10.11FLADD1302 pKa = 4.15AGCSGGAYY1310 pKa = 10.08DD1311 pKa = 6.15IIICDD1316 pKa = 3.74EE1317 pKa = 4.25CHH1319 pKa = 6.0STDD1322 pKa = 3.09ATSISGIGTVLDD1334 pKa = 3.65QAEE1337 pKa = 4.26TAGARR1342 pKa = 11.84LVVLATATPPGSVTVSHH1359 pKa = 6.82PNIEE1363 pKa = 4.18EE1364 pKa = 4.2VALSTTGEE1372 pKa = 3.72IPFYY1376 pKa = 11.01GKK1378 pKa = 10.47AIPLEE1383 pKa = 4.31VIKK1386 pKa = 10.68GGRR1389 pKa = 11.84HH1390 pKa = 7.03LIFCHH1395 pKa = 6.09SKK1397 pKa = 10.46KK1398 pKa = 10.67KK1399 pKa = 10.24CDD1401 pKa = 3.38EE1402 pKa = 4.26LAAKK1406 pKa = 10.12LVALGINAVAYY1417 pKa = 10.38YY1418 pKa = 10.17RR1419 pKa = 11.84GLDD1422 pKa = 3.32VSVIPTSGDD1431 pKa = 3.46VVVVSTDD1438 pKa = 2.93ALMTGFTGDD1447 pKa = 3.43FDD1449 pKa = 5.59SVIDD1453 pKa = 4.35CNTCVTQTVDD1463 pKa = 4.01FSLDD1467 pKa = 3.24PTFTIEE1473 pKa = 4.28TTTLPQDD1480 pKa = 3.32AVSRR1484 pKa = 11.84TQRR1487 pKa = 11.84RR1488 pKa = 11.84GRR1490 pKa = 11.84TGRR1493 pKa = 11.84GKK1495 pKa = 9.03PGIYY1499 pKa = 9.71RR1500 pKa = 11.84FVAPGEE1506 pKa = 4.31RR1507 pKa = 11.84PSGMFDD1513 pKa = 3.15SSVLCEE1519 pKa = 4.99CYY1521 pKa = 10.23DD1522 pKa = 4.46AGCAWYY1528 pKa = 9.49EE1529 pKa = 3.86LTPAEE1534 pKa = 4.18TTVRR1538 pKa = 11.84LRR1540 pKa = 11.84AYY1542 pKa = 9.06MNTPGLPVCQDD1553 pKa = 3.24HH1554 pKa = 6.85LGFWEE1559 pKa = 5.27GVFTGLTHH1567 pKa = 7.16IDD1569 pKa = 3.13AHH1571 pKa = 6.25FLSQTKK1577 pKa = 9.84QSGEE1581 pKa = 3.84NFPYY1585 pKa = 10.4LVAYY1589 pKa = 8.99QATVCARR1596 pKa = 11.84AQAPPPSWDD1605 pKa = 3.29QMRR1608 pKa = 11.84KK1609 pKa = 9.45CLIRR1613 pKa = 11.84LKK1615 pKa = 9.49PTLHH1619 pKa = 6.57GPTPLLYY1626 pKa = 10.61RR1627 pKa = 11.84LGAVQNEE1634 pKa = 4.33VTLTHH1639 pKa = 7.6PITKK1643 pKa = 10.38YY1644 pKa = 10.98IMTCMSADD1652 pKa = 3.78LEE1654 pKa = 4.94VVTSTWVLVGGVLAALAAYY1673 pKa = 9.06CLSTGCVVIVGRR1685 pKa = 11.84IVLSGKK1691 pKa = 9.21PAIIPDD1697 pKa = 3.83RR1698 pKa = 11.84EE1699 pKa = 3.98VLYY1702 pKa = 10.91QEE1704 pKa = 3.92FDD1706 pKa = 3.34EE1707 pKa = 5.03MEE1709 pKa = 4.51EE1710 pKa = 4.45CSQHH1714 pKa = 6.62LPYY1717 pKa = 10.02IEE1719 pKa = 3.91QGMMLAEE1726 pKa = 4.03QFKK1729 pKa = 10.74QKK1731 pKa = 11.03ALGLLQTASRR1741 pKa = 11.84HH1742 pKa = 5.59AEE1744 pKa = 4.06VITPAVQTNWQKK1756 pKa = 11.64LEE1758 pKa = 4.19VFWAKK1763 pKa = 10.68HH1764 pKa = 3.93MWNFISGIQYY1774 pKa = 10.64LAGLSTLPGNPAIASLMAFTAAVTSPLTTGQTLLFNILGGWVAAQLAAPGAATAFVGAGLAGAALDD1840 pKa = 3.89SVGLGKK1846 pKa = 10.64VLVDD1850 pKa = 3.24ILAGYY1855 pKa = 8.94GAGVAGALVAFKK1867 pKa = 10.47IMSGEE1872 pKa = 4.18VPSTEE1877 pKa = 4.51DD1878 pKa = 4.52LVNLLPAILSPGALAVGVVFASILRR1903 pKa = 11.84RR1904 pKa = 11.84RR1905 pKa = 11.84VGPGEE1910 pKa = 4.82GAVQWMNRR1918 pKa = 11.84LIAFASRR1925 pKa = 11.84GNHH1928 pKa = 5.24VSPTHH1933 pKa = 5.58YY1934 pKa = 10.73VPEE1937 pKa = 4.92SDD1939 pKa = 3.03AAARR1943 pKa = 11.84VTAILSSLTVTQLLRR1958 pKa = 11.84RR1959 pKa = 11.84LHH1961 pKa = 5.2QWISSEE1967 pKa = 4.01CTTPCSGSWLRR1978 pKa = 11.84DD1979 pKa = 2.72IWDD1982 pKa = 4.44WICEE1986 pKa = 4.08VLSDD1990 pKa = 4.42FKK1992 pKa = 10.84TWLKK1996 pKa = 10.72AKK1998 pKa = 10.38LMPQLPGIPFVSCQRR2013 pKa = 11.84GYY2015 pKa = 10.33RR2016 pKa = 11.84GVWRR2020 pKa = 11.84GDD2022 pKa = 3.27GIMHH2026 pKa = 6.34TRR2028 pKa = 11.84CHH2030 pKa = 6.78CGAEE2034 pKa = 4.16ITGHH2038 pKa = 5.15VKK2040 pKa = 10.42NGTMRR2045 pKa = 11.84IVGPRR2050 pKa = 11.84TCKK2053 pKa = 10.73NMWSGTFFINAYY2065 pKa = 5.29TTGPCTPLPAPNYY2078 pKa = 10.05KK2079 pKa = 9.79FALWRR2084 pKa = 11.84VSAEE2088 pKa = 3.84EE2089 pKa = 3.76YY2090 pKa = 10.35VEE2092 pKa = 3.73IRR2094 pKa = 11.84RR2095 pKa = 11.84VGDD2098 pKa = 3.08FHH2100 pKa = 7.55YY2101 pKa = 10.94VSGMTTDD2108 pKa = 4.11NLKK2111 pKa = 10.63CPCQIPSPEE2120 pKa = 4.37FFTEE2124 pKa = 3.82LDD2126 pKa = 3.37GVRR2129 pKa = 11.84LHH2131 pKa = 7.21RR2132 pKa = 11.84FAPPCKK2138 pKa = 8.52PLLRR2142 pKa = 11.84EE2143 pKa = 3.9EE2144 pKa = 4.07VSFRR2148 pKa = 11.84VGLHH2152 pKa = 6.38EE2153 pKa = 4.41YY2154 pKa = 9.9PVGSQLPCEE2163 pKa = 4.63PEE2165 pKa = 3.85PDD2167 pKa = 3.85VAVLTSMLTDD2177 pKa = 4.35PSHH2180 pKa = 6.11ITAEE2184 pKa = 3.99AAGRR2188 pKa = 11.84RR2189 pKa = 11.84LARR2192 pKa = 11.84GSPPSMASSSASQLSAPSLKK2212 pKa = 9.61ATCTANHH2219 pKa = 7.33DD2220 pKa = 4.11SPDD2223 pKa = 3.62AEE2225 pKa = 4.57LIEE2228 pKa = 5.73ANLLWRR2234 pKa = 11.84QEE2236 pKa = 3.79MGGNITRR2243 pKa = 11.84VEE2245 pKa = 4.29SEE2247 pKa = 4.21NKK2249 pKa = 9.79VVILDD2254 pKa = 3.76SFDD2257 pKa = 3.91PLVAEE2262 pKa = 3.98EE2263 pKa = 4.72DD2264 pKa = 3.66EE2265 pKa = 5.33RR2266 pKa = 11.84EE2267 pKa = 4.07VSVPAEE2273 pKa = 3.9ILRR2276 pKa = 11.84KK2277 pKa = 9.2SRR2279 pKa = 11.84RR2280 pKa = 11.84FAPALPVWARR2290 pKa = 11.84PDD2292 pKa = 3.69YY2293 pKa = 11.17NPLLVEE2299 pKa = 4.18TWKK2302 pKa = 11.07KK2303 pKa = 10.12PDD2305 pKa = 3.4YY2306 pKa = 9.87EE2307 pKa = 4.22PPVVHH2312 pKa = 6.88GCPLPPPRR2320 pKa = 11.84SPPVPPPRR2328 pKa = 11.84KK2329 pKa = 9.32KK2330 pKa = 9.26RR2331 pKa = 11.84TVVLTEE2337 pKa = 4.01STLPTALAEE2346 pKa = 4.12LATKK2350 pKa = 10.64SFGSSSTSGITGDD2363 pKa = 3.34NTTTSSEE2370 pKa = 4.21PAPSGCPPDD2379 pKa = 4.46SDD2381 pKa = 4.06VEE2383 pKa = 4.89SYY2385 pKa = 11.76SSMPPLEE2392 pKa = 4.89GEE2394 pKa = 4.49PGDD2397 pKa = 4.71PDD2399 pKa = 4.59LSDD2402 pKa = 4.68GSWSTVSSGADD2413 pKa = 3.22TEE2415 pKa = 5.7DD2416 pKa = 3.75VVCCSMSYY2424 pKa = 9.74SWTGALVTPCAAEE2437 pKa = 4.08EE2438 pKa = 3.95QKK2440 pKa = 11.27LPINALSNSLLRR2452 pKa = 11.84HH2453 pKa = 5.91HH2454 pKa = 6.6NLVYY2458 pKa = 10.19STTSRR2463 pKa = 11.84SACQRR2468 pKa = 11.84KK2469 pKa = 9.69KK2470 pKa = 10.74KK2471 pKa = 9.11VTFDD2475 pKa = 3.28RR2476 pKa = 11.84LQVLDD2481 pKa = 3.64SHH2483 pKa = 6.38YY2484 pKa = 11.03QDD2486 pKa = 3.18VLKK2489 pKa = 10.3EE2490 pKa = 4.1VKK2492 pKa = 10.12AAASKK2497 pKa = 10.94VKK2499 pKa = 10.82ANLLSVEE2506 pKa = 4.58EE2507 pKa = 4.54ACSLAPPHH2515 pKa = 5.95SAKK2518 pKa = 10.84SKK2520 pKa = 9.96FGYY2523 pKa = 8.84GAKK2526 pKa = 10.04DD2527 pKa = 3.57VRR2529 pKa = 11.84CHH2531 pKa = 5.43ARR2533 pKa = 11.84KK2534 pKa = 9.39AVAHH2538 pKa = 6.62INSVWKK2544 pKa = 10.39DD2545 pKa = 3.56LLEE2548 pKa = 5.19DD2549 pKa = 3.65SVTPIDD2555 pKa = 3.68TTIMAKK2561 pKa = 10.35NEE2563 pKa = 4.13VFCVQPEE2570 pKa = 3.99KK2571 pKa = 10.89GGRR2574 pKa = 11.84KK2575 pKa = 7.4PARR2578 pKa = 11.84LIVFPDD2584 pKa = 3.52LGVRR2588 pKa = 11.84VCEE2591 pKa = 4.62KK2592 pKa = 9.4MALYY2596 pKa = 10.52DD2597 pKa = 3.92VVSKK2601 pKa = 11.21LPLAVMGSSYY2611 pKa = 10.91GFQYY2615 pKa = 11.03SPGQRR2620 pKa = 11.84VEE2622 pKa = 4.48FLVQAWKK2629 pKa = 10.61SKK2631 pKa = 7.47KK2632 pKa = 8.39TPMGLSYY2639 pKa = 9.72DD2640 pKa = 3.87TRR2642 pKa = 11.84CFDD2645 pKa = 3.63STVTEE2650 pKa = 3.89SDD2652 pKa = 2.71IRR2654 pKa = 11.84TEE2656 pKa = 3.75EE2657 pKa = 5.27AIYY2660 pKa = 9.91QCCDD2664 pKa = 3.64LDD2666 pKa = 3.69PQARR2670 pKa = 11.84VAIKK2674 pKa = 10.52SLTEE2678 pKa = 3.57RR2679 pKa = 11.84LYY2681 pKa = 11.41VGGPLTNSRR2690 pKa = 11.84GEE2692 pKa = 3.79NCGYY2696 pKa = 9.73RR2697 pKa = 11.84RR2698 pKa = 11.84CRR2700 pKa = 11.84ASRR2703 pKa = 11.84VLTTSCGNTLTRR2715 pKa = 11.84YY2716 pKa = 8.94IKK2718 pKa = 10.68ARR2720 pKa = 11.84AACRR2724 pKa = 11.84AAGLQDD2730 pKa = 3.51CTMLVCGDD2738 pKa = 4.34DD2739 pKa = 3.57LVVICEE2745 pKa = 4.23SAGVQEE2751 pKa = 4.81DD2752 pKa = 3.9AASLRR2757 pKa = 11.84AFTEE2761 pKa = 3.53AMTRR2765 pKa = 11.84YY2766 pKa = 8.86SAPPGDD2772 pKa = 4.37PPQPEE2777 pKa = 4.22YY2778 pKa = 11.02DD2779 pKa = 3.7LEE2781 pKa = 5.89LITSCSSNVSVAHH2794 pKa = 6.84DD2795 pKa = 3.78GAGKK2799 pKa = 9.8RR2800 pKa = 11.84VYY2802 pKa = 10.88YY2803 pKa = 8.66LTRR2806 pKa = 11.84DD2807 pKa = 3.34PTTPLARR2814 pKa = 11.84AAWEE2818 pKa = 4.37TARR2821 pKa = 11.84HH2822 pKa = 5.17TPVNSWLGNIIMFAPTLWARR2842 pKa = 11.84MILMTHH2848 pKa = 6.46FFSVLIARR2856 pKa = 11.84DD2857 pKa = 3.58QLEE2860 pKa = 3.83QALNCEE2866 pKa = 4.7IYY2868 pKa = 10.02GACYY2872 pKa = 10.27SIEE2875 pKa = 4.28PLDD2878 pKa = 4.68LPPIIQRR2885 pKa = 11.84LHH2887 pKa = 5.87GLSAFSLHH2895 pKa = 6.68SYY2897 pKa = 10.7SPGEE2901 pKa = 3.99INRR2904 pKa = 11.84VAACLRR2910 pKa = 11.84KK2911 pKa = 10.11LGVPPLRR2918 pKa = 11.84AWRR2921 pKa = 11.84HH2922 pKa = 4.79RR2923 pKa = 11.84AWSVRR2928 pKa = 11.84ARR2930 pKa = 11.84LLARR2934 pKa = 11.84GGKK2937 pKa = 9.39AAICGKK2943 pKa = 10.11YY2944 pKa = 9.84LFNWAVRR2951 pKa = 11.84TKK2953 pKa = 11.03LKK2955 pKa = 9.21LTPITAAGRR2964 pKa = 11.84LDD2966 pKa = 3.52LSGWFTAGYY2975 pKa = 9.49SGGDD2979 pKa = 3.05IYY2981 pKa = 11.16HH2982 pKa = 6.29SVSHH2986 pKa = 6.73ARR2988 pKa = 11.84PRR2990 pKa = 11.84WFWFCLLLLAAGVGIYY3006 pKa = 10.22LLPNRR3011 pKa = 4.87
MM1 pKa = 7.02STNPKK6 pKa = 8.89PQRR9 pKa = 11.84KK10 pKa = 6.64TKK12 pKa = 10.42RR13 pKa = 11.84NTNRR17 pKa = 11.84RR18 pKa = 11.84PQDD21 pKa = 3.19VKK23 pKa = 11.12FPGGGQIVGGVYY35 pKa = 10.66LLPRR39 pKa = 11.84RR40 pKa = 11.84GPRR43 pKa = 11.84LGVRR47 pKa = 11.84ATRR50 pKa = 11.84KK51 pKa = 7.58TSEE54 pKa = 3.85RR55 pKa = 11.84SQPRR59 pKa = 11.84GRR61 pKa = 11.84RR62 pKa = 11.84QPIPKK67 pKa = 9.59ARR69 pKa = 11.84RR70 pKa = 11.84PEE72 pKa = 3.84GRR74 pKa = 11.84TWAQPGYY81 pKa = 9.32PWPLYY86 pKa = 10.66GNEE89 pKa = 4.09GCGWAGWLLSPRR101 pKa = 11.84GSRR104 pKa = 11.84PSWGPTDD111 pKa = 3.29PRR113 pKa = 11.84RR114 pKa = 11.84RR115 pKa = 11.84SRR117 pKa = 11.84NLGKK121 pKa = 10.85VIDD124 pKa = 3.97TLTCGFADD132 pKa = 3.75LMGYY136 pKa = 9.34IPLVGAPLGGAARR149 pKa = 11.84ALAHH153 pKa = 5.78GVRR156 pKa = 11.84VLEE159 pKa = 5.04DD160 pKa = 3.44GVNYY164 pKa = 8.67ATGNLPGCSFSIFLLALLSCLTVPASAYY192 pKa = 7.58QVRR195 pKa = 11.84NSSGLYY201 pKa = 10.01HH202 pKa = 5.77VTNDD206 pKa = 3.94CPNSSVVYY214 pKa = 9.19EE215 pKa = 4.02AADD218 pKa = 4.68AILHH222 pKa = 5.76TPGCVPCVRR231 pKa = 11.84EE232 pKa = 4.55GNASRR237 pKa = 11.84CWVAVTPTVATRR249 pKa = 11.84DD250 pKa = 3.51GKK252 pKa = 11.25LPTTQLRR259 pKa = 11.84RR260 pKa = 11.84HH261 pKa = 6.37IDD263 pKa = 3.6LLVGSATLCSALYY276 pKa = 10.88VGDD279 pKa = 3.7LCGSVFLVGQLFTFSPRR296 pKa = 11.84HH297 pKa = 5.22HH298 pKa = 6.95WTTQDD303 pKa = 4.11CNCSIYY309 pKa = 9.95PGHH312 pKa = 6.19ITGHH316 pKa = 5.05RR317 pKa = 11.84MAWNMMMNWSPTAALVVAQLLRR339 pKa = 11.84IPQAIMDD346 pKa = 4.91MIAGAHH352 pKa = 5.67WGVLAGIKK360 pKa = 9.59YY361 pKa = 10.47FSMVGNWAKK370 pKa = 10.94VLVVLLLFAGVDD382 pKa = 3.57AEE384 pKa = 4.48THH386 pKa = 4.24VTGGNAGRR394 pKa = 11.84TTAGLVGLLTPGAKK408 pKa = 9.75QNIQLINTNGSWHH421 pKa = 6.65INSTALNCNEE431 pKa = 4.19SLNTGWLAGLFYY443 pKa = 9.73QHH445 pKa = 6.89KK446 pKa = 9.47FNSSGCPEE454 pKa = 4.06RR455 pKa = 11.84LASCRR460 pKa = 11.84RR461 pKa = 11.84LTDD464 pKa = 4.35FAQGWGPISYY474 pKa = 10.96ANGSGLDD481 pKa = 3.41EE482 pKa = 5.9RR483 pKa = 11.84PYY485 pKa = 10.22CWHH488 pKa = 6.35YY489 pKa = 10.29PPRR492 pKa = 11.84PCGIVPAKK500 pKa = 9.97SVCGPVYY507 pKa = 10.55CFTPSPVVVGTTDD520 pKa = 3.09RR521 pKa = 11.84SGAPTYY527 pKa = 11.0SWGANDD533 pKa = 3.4TDD535 pKa = 4.23VFVLNNTRR543 pKa = 11.84PPLGNWFGCTWMNSTGFTKK562 pKa = 10.5VCGAPPCVIGGVGNNTLLCPTDD584 pKa = 3.81CFRR587 pKa = 11.84KK588 pKa = 10.09YY589 pKa = 10.54PEE591 pKa = 4.06ATYY594 pKa = 10.48SRR596 pKa = 11.84CGSGPRR602 pKa = 11.84ITPRR606 pKa = 11.84CMVDD610 pKa = 2.96YY611 pKa = 9.47PYY613 pKa = 11.11RR614 pKa = 11.84LWHH617 pKa = 5.87YY618 pKa = 9.2PCTINYY624 pKa = 7.46TIFKK628 pKa = 9.44VRR630 pKa = 11.84MYY632 pKa = 10.87VGGVEE637 pKa = 4.23HH638 pKa = 7.17RR639 pKa = 11.84LEE641 pKa = 4.47AACNWTRR648 pKa = 11.84GEE650 pKa = 4.08RR651 pKa = 11.84CDD653 pKa = 5.26LEE655 pKa = 5.56DD656 pKa = 4.43RR657 pKa = 11.84DD658 pKa = 4.2RR659 pKa = 11.84SEE661 pKa = 5.24LSPLLLSTTQWQVLPCSFTTLPALSTGLIHH691 pKa = 6.97LHH693 pKa = 5.11QNIVDD698 pKa = 3.63VQYY701 pKa = 11.06LYY703 pKa = 11.42GVGSSIASWAIKK715 pKa = 9.15WEE717 pKa = 4.14YY718 pKa = 10.9VVLLFLLLADD728 pKa = 4.95ARR730 pKa = 11.84VCSCLWMMLLISQAEE745 pKa = 3.93AALEE749 pKa = 3.82NLVILNAASLAGTHH763 pKa = 6.1GLVSFLVFFCFAWYY777 pKa = 10.26LKK779 pKa = 10.06GRR781 pKa = 11.84WVPGAVYY788 pKa = 10.37ALYY791 pKa = 10.84GMWPLLLLLLALPQRR806 pKa = 11.84AYY808 pKa = 10.83ALDD811 pKa = 3.8TEE813 pKa = 4.98VAASCGGVVLVGLMALTLSPYY834 pKa = 8.32YY835 pKa = 10.31KK836 pKa = 10.1RR837 pKa = 11.84YY838 pKa = 10.03ISWCMWWLQYY848 pKa = 11.18FLTRR852 pKa = 11.84VEE854 pKa = 4.29AQLHH858 pKa = 4.93VWVPPLNVRR867 pKa = 11.84GGRR870 pKa = 11.84DD871 pKa = 3.28AVILLTCVVHH881 pKa = 6.24PALVFDD887 pKa = 3.65ITKK890 pKa = 10.55LLLAIFGPLWILQASLLKK908 pKa = 9.99VPYY911 pKa = 9.43FVRR914 pKa = 11.84VQGLLRR920 pKa = 11.84ICALARR926 pKa = 11.84KK927 pKa = 8.7IAGGHH932 pKa = 4.48YY933 pKa = 9.9VQMAIIKK940 pKa = 10.04LGALTGTCVYY950 pKa = 10.98NHH952 pKa = 7.36LAPLRR957 pKa = 11.84DD958 pKa = 3.39WAHH961 pKa = 5.92NGLRR965 pKa = 11.84DD966 pKa = 3.47LAVAVEE972 pKa = 4.1PVVFSRR978 pKa = 11.84MEE980 pKa = 4.01TKK982 pKa = 10.85LITWGADD989 pKa = 2.86TAACGDD995 pKa = 4.67IINGLPVSARR1005 pKa = 11.84RR1006 pKa = 11.84GQEE1009 pKa = 3.59ILLGPADD1016 pKa = 3.85GMVSKK1021 pKa = 10.42GWRR1024 pKa = 11.84LLAPITAYY1032 pKa = 10.28AQQTRR1037 pKa = 11.84GLLGCIITSLTGRR1050 pKa = 11.84DD1051 pKa = 3.34KK1052 pKa = 11.42NQVEE1056 pKa = 4.54GEE1058 pKa = 4.27VQIVSTATQTFLATCINGVCWTVYY1082 pKa = 10.09HH1083 pKa = 6.4GAGTRR1088 pKa = 11.84TIASPKK1094 pKa = 9.79GPVIQTYY1101 pKa = 9.49TNVDD1105 pKa = 3.03QDD1107 pKa = 4.21LVGWPAPQGSRR1118 pKa = 11.84SLTPCTCGSSDD1129 pKa = 3.64LYY1131 pKa = 11.23LVTRR1135 pKa = 11.84HH1136 pKa = 6.28ADD1138 pKa = 3.45VIPVRR1143 pKa = 11.84RR1144 pKa = 11.84RR1145 pKa = 11.84GDD1147 pKa = 3.24SRR1149 pKa = 11.84GSLLSPRR1156 pKa = 11.84PISYY1160 pKa = 10.76LKK1162 pKa = 10.52GSSGGPLLCPTGHH1175 pKa = 6.91AVGLFRR1181 pKa = 11.84AAVCTRR1187 pKa = 11.84GVAKK1191 pKa = 10.32AVDD1194 pKa = 4.84FIPVEE1199 pKa = 4.0NLEE1202 pKa = 4.23TTMRR1206 pKa = 11.84SPVFTDD1212 pKa = 3.2NSSPPAVPQSFQVAHH1227 pKa = 6.25LHH1229 pKa = 6.36APTGSGKK1236 pKa = 7.57STKK1239 pKa = 10.21VPAAYY1244 pKa = 9.45AAKK1247 pKa = 9.7GYY1249 pKa = 10.15KK1250 pKa = 9.95VLVLNPSVAATLGFGAYY1267 pKa = 8.02MSKK1270 pKa = 10.38AHH1272 pKa = 6.52GVDD1275 pKa = 3.36PNIRR1279 pKa = 11.84TGVRR1283 pKa = 11.84TITTGSPITYY1293 pKa = 8.3STYY1296 pKa = 11.23GKK1298 pKa = 10.11FLADD1302 pKa = 4.15AGCSGGAYY1310 pKa = 10.08DD1311 pKa = 6.15IIICDD1316 pKa = 3.74EE1317 pKa = 4.25CHH1319 pKa = 6.0STDD1322 pKa = 3.09ATSISGIGTVLDD1334 pKa = 3.65QAEE1337 pKa = 4.26TAGARR1342 pKa = 11.84LVVLATATPPGSVTVSHH1359 pKa = 6.82PNIEE1363 pKa = 4.18EE1364 pKa = 4.2VALSTTGEE1372 pKa = 3.72IPFYY1376 pKa = 11.01GKK1378 pKa = 10.47AIPLEE1383 pKa = 4.31VIKK1386 pKa = 10.68GGRR1389 pKa = 11.84HH1390 pKa = 7.03LIFCHH1395 pKa = 6.09SKK1397 pKa = 10.46KK1398 pKa = 10.67KK1399 pKa = 10.24CDD1401 pKa = 3.38EE1402 pKa = 4.26LAAKK1406 pKa = 10.12LVALGINAVAYY1417 pKa = 10.38YY1418 pKa = 10.17RR1419 pKa = 11.84GLDD1422 pKa = 3.32VSVIPTSGDD1431 pKa = 3.46VVVVSTDD1438 pKa = 2.93ALMTGFTGDD1447 pKa = 3.43FDD1449 pKa = 5.59SVIDD1453 pKa = 4.35CNTCVTQTVDD1463 pKa = 4.01FSLDD1467 pKa = 3.24PTFTIEE1473 pKa = 4.28TTTLPQDD1480 pKa = 3.32AVSRR1484 pKa = 11.84TQRR1487 pKa = 11.84RR1488 pKa = 11.84GRR1490 pKa = 11.84TGRR1493 pKa = 11.84GKK1495 pKa = 9.03PGIYY1499 pKa = 9.71RR1500 pKa = 11.84FVAPGEE1506 pKa = 4.31RR1507 pKa = 11.84PSGMFDD1513 pKa = 3.15SSVLCEE1519 pKa = 4.99CYY1521 pKa = 10.23DD1522 pKa = 4.46AGCAWYY1528 pKa = 9.49EE1529 pKa = 3.86LTPAEE1534 pKa = 4.18TTVRR1538 pKa = 11.84LRR1540 pKa = 11.84AYY1542 pKa = 9.06MNTPGLPVCQDD1553 pKa = 3.24HH1554 pKa = 6.85LGFWEE1559 pKa = 5.27GVFTGLTHH1567 pKa = 7.16IDD1569 pKa = 3.13AHH1571 pKa = 6.25FLSQTKK1577 pKa = 9.84QSGEE1581 pKa = 3.84NFPYY1585 pKa = 10.4LVAYY1589 pKa = 8.99QATVCARR1596 pKa = 11.84AQAPPPSWDD1605 pKa = 3.29QMRR1608 pKa = 11.84KK1609 pKa = 9.45CLIRR1613 pKa = 11.84LKK1615 pKa = 9.49PTLHH1619 pKa = 6.57GPTPLLYY1626 pKa = 10.61RR1627 pKa = 11.84LGAVQNEE1634 pKa = 4.33VTLTHH1639 pKa = 7.6PITKK1643 pKa = 10.38YY1644 pKa = 10.98IMTCMSADD1652 pKa = 3.78LEE1654 pKa = 4.94VVTSTWVLVGGVLAALAAYY1673 pKa = 9.06CLSTGCVVIVGRR1685 pKa = 11.84IVLSGKK1691 pKa = 9.21PAIIPDD1697 pKa = 3.83RR1698 pKa = 11.84EE1699 pKa = 3.98VLYY1702 pKa = 10.91QEE1704 pKa = 3.92FDD1706 pKa = 3.34EE1707 pKa = 5.03MEE1709 pKa = 4.51EE1710 pKa = 4.45CSQHH1714 pKa = 6.62LPYY1717 pKa = 10.02IEE1719 pKa = 3.91QGMMLAEE1726 pKa = 4.03QFKK1729 pKa = 10.74QKK1731 pKa = 11.03ALGLLQTASRR1741 pKa = 11.84HH1742 pKa = 5.59AEE1744 pKa = 4.06VITPAVQTNWQKK1756 pKa = 11.64LEE1758 pKa = 4.19VFWAKK1763 pKa = 10.68HH1764 pKa = 3.93MWNFISGIQYY1774 pKa = 10.64LAGLSTLPGNPAIASLMAFTAAVTSPLTTGQTLLFNILGGWVAAQLAAPGAATAFVGAGLAGAALDD1840 pKa = 3.89SVGLGKK1846 pKa = 10.64VLVDD1850 pKa = 3.24ILAGYY1855 pKa = 8.94GAGVAGALVAFKK1867 pKa = 10.47IMSGEE1872 pKa = 4.18VPSTEE1877 pKa = 4.51DD1878 pKa = 4.52LVNLLPAILSPGALAVGVVFASILRR1903 pKa = 11.84RR1904 pKa = 11.84RR1905 pKa = 11.84VGPGEE1910 pKa = 4.82GAVQWMNRR1918 pKa = 11.84LIAFASRR1925 pKa = 11.84GNHH1928 pKa = 5.24VSPTHH1933 pKa = 5.58YY1934 pKa = 10.73VPEE1937 pKa = 4.92SDD1939 pKa = 3.03AAARR1943 pKa = 11.84VTAILSSLTVTQLLRR1958 pKa = 11.84RR1959 pKa = 11.84LHH1961 pKa = 5.2QWISSEE1967 pKa = 4.01CTTPCSGSWLRR1978 pKa = 11.84DD1979 pKa = 2.72IWDD1982 pKa = 4.44WICEE1986 pKa = 4.08VLSDD1990 pKa = 4.42FKK1992 pKa = 10.84TWLKK1996 pKa = 10.72AKK1998 pKa = 10.38LMPQLPGIPFVSCQRR2013 pKa = 11.84GYY2015 pKa = 10.33RR2016 pKa = 11.84GVWRR2020 pKa = 11.84GDD2022 pKa = 3.27GIMHH2026 pKa = 6.34TRR2028 pKa = 11.84CHH2030 pKa = 6.78CGAEE2034 pKa = 4.16ITGHH2038 pKa = 5.15VKK2040 pKa = 10.42NGTMRR2045 pKa = 11.84IVGPRR2050 pKa = 11.84TCKK2053 pKa = 10.73NMWSGTFFINAYY2065 pKa = 5.29TTGPCTPLPAPNYY2078 pKa = 10.05KK2079 pKa = 9.79FALWRR2084 pKa = 11.84VSAEE2088 pKa = 3.84EE2089 pKa = 3.76YY2090 pKa = 10.35VEE2092 pKa = 3.73IRR2094 pKa = 11.84RR2095 pKa = 11.84VGDD2098 pKa = 3.08FHH2100 pKa = 7.55YY2101 pKa = 10.94VSGMTTDD2108 pKa = 4.11NLKK2111 pKa = 10.63CPCQIPSPEE2120 pKa = 4.37FFTEE2124 pKa = 3.82LDD2126 pKa = 3.37GVRR2129 pKa = 11.84LHH2131 pKa = 7.21RR2132 pKa = 11.84FAPPCKK2138 pKa = 8.52PLLRR2142 pKa = 11.84EE2143 pKa = 3.9EE2144 pKa = 4.07VSFRR2148 pKa = 11.84VGLHH2152 pKa = 6.38EE2153 pKa = 4.41YY2154 pKa = 9.9PVGSQLPCEE2163 pKa = 4.63PEE2165 pKa = 3.85PDD2167 pKa = 3.85VAVLTSMLTDD2177 pKa = 4.35PSHH2180 pKa = 6.11ITAEE2184 pKa = 3.99AAGRR2188 pKa = 11.84RR2189 pKa = 11.84LARR2192 pKa = 11.84GSPPSMASSSASQLSAPSLKK2212 pKa = 9.61ATCTANHH2219 pKa = 7.33DD2220 pKa = 4.11SPDD2223 pKa = 3.62AEE2225 pKa = 4.57LIEE2228 pKa = 5.73ANLLWRR2234 pKa = 11.84QEE2236 pKa = 3.79MGGNITRR2243 pKa = 11.84VEE2245 pKa = 4.29SEE2247 pKa = 4.21NKK2249 pKa = 9.79VVILDD2254 pKa = 3.76SFDD2257 pKa = 3.91PLVAEE2262 pKa = 3.98EE2263 pKa = 4.72DD2264 pKa = 3.66EE2265 pKa = 5.33RR2266 pKa = 11.84EE2267 pKa = 4.07VSVPAEE2273 pKa = 3.9ILRR2276 pKa = 11.84KK2277 pKa = 9.2SRR2279 pKa = 11.84RR2280 pKa = 11.84FAPALPVWARR2290 pKa = 11.84PDD2292 pKa = 3.69YY2293 pKa = 11.17NPLLVEE2299 pKa = 4.18TWKK2302 pKa = 11.07KK2303 pKa = 10.12PDD2305 pKa = 3.4YY2306 pKa = 9.87EE2307 pKa = 4.22PPVVHH2312 pKa = 6.88GCPLPPPRR2320 pKa = 11.84SPPVPPPRR2328 pKa = 11.84KK2329 pKa = 9.32KK2330 pKa = 9.26RR2331 pKa = 11.84TVVLTEE2337 pKa = 4.01STLPTALAEE2346 pKa = 4.12LATKK2350 pKa = 10.64SFGSSSTSGITGDD2363 pKa = 3.34NTTTSSEE2370 pKa = 4.21PAPSGCPPDD2379 pKa = 4.46SDD2381 pKa = 4.06VEE2383 pKa = 4.89SYY2385 pKa = 11.76SSMPPLEE2392 pKa = 4.89GEE2394 pKa = 4.49PGDD2397 pKa = 4.71PDD2399 pKa = 4.59LSDD2402 pKa = 4.68GSWSTVSSGADD2413 pKa = 3.22TEE2415 pKa = 5.7DD2416 pKa = 3.75VVCCSMSYY2424 pKa = 9.74SWTGALVTPCAAEE2437 pKa = 4.08EE2438 pKa = 3.95QKK2440 pKa = 11.27LPINALSNSLLRR2452 pKa = 11.84HH2453 pKa = 5.91HH2454 pKa = 6.6NLVYY2458 pKa = 10.19STTSRR2463 pKa = 11.84SACQRR2468 pKa = 11.84KK2469 pKa = 9.69KK2470 pKa = 10.74KK2471 pKa = 9.11VTFDD2475 pKa = 3.28RR2476 pKa = 11.84LQVLDD2481 pKa = 3.64SHH2483 pKa = 6.38YY2484 pKa = 11.03QDD2486 pKa = 3.18VLKK2489 pKa = 10.3EE2490 pKa = 4.1VKK2492 pKa = 10.12AAASKK2497 pKa = 10.94VKK2499 pKa = 10.82ANLLSVEE2506 pKa = 4.58EE2507 pKa = 4.54ACSLAPPHH2515 pKa = 5.95SAKK2518 pKa = 10.84SKK2520 pKa = 9.96FGYY2523 pKa = 8.84GAKK2526 pKa = 10.04DD2527 pKa = 3.57VRR2529 pKa = 11.84CHH2531 pKa = 5.43ARR2533 pKa = 11.84KK2534 pKa = 9.39AVAHH2538 pKa = 6.62INSVWKK2544 pKa = 10.39DD2545 pKa = 3.56LLEE2548 pKa = 5.19DD2549 pKa = 3.65SVTPIDD2555 pKa = 3.68TTIMAKK2561 pKa = 10.35NEE2563 pKa = 4.13VFCVQPEE2570 pKa = 3.99KK2571 pKa = 10.89GGRR2574 pKa = 11.84KK2575 pKa = 7.4PARR2578 pKa = 11.84LIVFPDD2584 pKa = 3.52LGVRR2588 pKa = 11.84VCEE2591 pKa = 4.62KK2592 pKa = 9.4MALYY2596 pKa = 10.52DD2597 pKa = 3.92VVSKK2601 pKa = 11.21LPLAVMGSSYY2611 pKa = 10.91GFQYY2615 pKa = 11.03SPGQRR2620 pKa = 11.84VEE2622 pKa = 4.48FLVQAWKK2629 pKa = 10.61SKK2631 pKa = 7.47KK2632 pKa = 8.39TPMGLSYY2639 pKa = 9.72DD2640 pKa = 3.87TRR2642 pKa = 11.84CFDD2645 pKa = 3.63STVTEE2650 pKa = 3.89SDD2652 pKa = 2.71IRR2654 pKa = 11.84TEE2656 pKa = 3.75EE2657 pKa = 5.27AIYY2660 pKa = 9.91QCCDD2664 pKa = 3.64LDD2666 pKa = 3.69PQARR2670 pKa = 11.84VAIKK2674 pKa = 10.52SLTEE2678 pKa = 3.57RR2679 pKa = 11.84LYY2681 pKa = 11.41VGGPLTNSRR2690 pKa = 11.84GEE2692 pKa = 3.79NCGYY2696 pKa = 9.73RR2697 pKa = 11.84RR2698 pKa = 11.84CRR2700 pKa = 11.84ASRR2703 pKa = 11.84VLTTSCGNTLTRR2715 pKa = 11.84YY2716 pKa = 8.94IKK2718 pKa = 10.68ARR2720 pKa = 11.84AACRR2724 pKa = 11.84AAGLQDD2730 pKa = 3.51CTMLVCGDD2738 pKa = 4.34DD2739 pKa = 3.57LVVICEE2745 pKa = 4.23SAGVQEE2751 pKa = 4.81DD2752 pKa = 3.9AASLRR2757 pKa = 11.84AFTEE2761 pKa = 3.53AMTRR2765 pKa = 11.84YY2766 pKa = 8.86SAPPGDD2772 pKa = 4.37PPQPEE2777 pKa = 4.22YY2778 pKa = 11.02DD2779 pKa = 3.7LEE2781 pKa = 5.89LITSCSSNVSVAHH2794 pKa = 6.84DD2795 pKa = 3.78GAGKK2799 pKa = 9.8RR2800 pKa = 11.84VYY2802 pKa = 10.88YY2803 pKa = 8.66LTRR2806 pKa = 11.84DD2807 pKa = 3.34PTTPLARR2814 pKa = 11.84AAWEE2818 pKa = 4.37TARR2821 pKa = 11.84HH2822 pKa = 5.17TPVNSWLGNIIMFAPTLWARR2842 pKa = 11.84MILMTHH2848 pKa = 6.46FFSVLIARR2856 pKa = 11.84DD2857 pKa = 3.58QLEE2860 pKa = 3.83QALNCEE2866 pKa = 4.7IYY2868 pKa = 10.02GACYY2872 pKa = 10.27SIEE2875 pKa = 4.28PLDD2878 pKa = 4.68LPPIIQRR2885 pKa = 11.84LHH2887 pKa = 5.87GLSAFSLHH2895 pKa = 6.68SYY2897 pKa = 10.7SPGEE2901 pKa = 3.99INRR2904 pKa = 11.84VAACLRR2910 pKa = 11.84KK2911 pKa = 10.11LGVPPLRR2918 pKa = 11.84AWRR2921 pKa = 11.84HH2922 pKa = 4.79RR2923 pKa = 11.84AWSVRR2928 pKa = 11.84ARR2930 pKa = 11.84LLARR2934 pKa = 11.84GGKK2937 pKa = 9.39AAICGKK2943 pKa = 10.11YY2944 pKa = 9.84LFNWAVRR2951 pKa = 11.84TKK2953 pKa = 11.03LKK2955 pKa = 9.21LTPITAAGRR2964 pKa = 11.84LDD2966 pKa = 3.52LSGWFTAGYY2975 pKa = 9.49SGGDD2979 pKa = 3.05IYY2981 pKa = 11.16HH2982 pKa = 6.29SVSHH2986 pKa = 6.73ARR2988 pKa = 11.84PRR2990 pKa = 11.84WFWFCLLLLAAGVGIYY3006 pKa = 10.22LLPNRR3011 pKa = 4.87
Molecular weight: 327.15 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>sp|P27958|POLG_HCV77 Genome polyprotein OS=Hepatitis C virus genotype 1a (isolate H77) OX=63746 PE=1 SV=3
MM1 pKa = 7.02STNPKK6 pKa = 8.94PQRR9 pKa = 11.84KK10 pKa = 8.75KK11 pKa = 10.41PNVTPTVAHH20 pKa = 6.1RR21 pKa = 11.84TSSSRR26 pKa = 11.84VAVRR30 pKa = 11.84SLVEE34 pKa = 4.58FTCCRR39 pKa = 11.84AGALDD44 pKa = 3.91WVCARR49 pKa = 11.84RR50 pKa = 11.84GRR52 pKa = 11.84LPSGRR57 pKa = 11.84NLEE60 pKa = 4.14VDD62 pKa = 3.43VSLSPRR68 pKa = 11.84HH69 pKa = 5.32VGPRR73 pKa = 11.84AGPGLSPGTLGPSMAMRR90 pKa = 11.84VAGGRR95 pKa = 11.84DD96 pKa = 4.36GSCLPVALGLAGAPQTPGVGRR117 pKa = 11.84AIWVRR122 pKa = 11.84SSIPLRR128 pKa = 11.84AASPTSWGTYY138 pKa = 8.93RR139 pKa = 11.84SSAPLLEE146 pKa = 4.67ALPGPWRR153 pKa = 11.84MASGFWKK160 pKa = 9.08TAA162 pKa = 3.09
MM1 pKa = 7.02STNPKK6 pKa = 8.94PQRR9 pKa = 11.84KK10 pKa = 8.75KK11 pKa = 10.41PNVTPTVAHH20 pKa = 6.1RR21 pKa = 11.84TSSSRR26 pKa = 11.84VAVRR30 pKa = 11.84SLVEE34 pKa = 4.58FTCCRR39 pKa = 11.84AGALDD44 pKa = 3.91WVCARR49 pKa = 11.84RR50 pKa = 11.84GRR52 pKa = 11.84LPSGRR57 pKa = 11.84NLEE60 pKa = 4.14VDD62 pKa = 3.43VSLSPRR68 pKa = 11.84HH69 pKa = 5.32VGPRR73 pKa = 11.84AGPGLSPGTLGPSMAMRR90 pKa = 11.84VAGGRR95 pKa = 11.84DD96 pKa = 4.36GSCLPVALGLAGAPQTPGVGRR117 pKa = 11.84AIWVRR122 pKa = 11.84SSIPLRR128 pKa = 11.84AASPTSWGTYY138 pKa = 8.93RR139 pKa = 11.84SSAPLLEE146 pKa = 4.67ALPGPWRR153 pKa = 11.84MASGFWKK160 pKa = 9.08TAA162 pKa = 3.09
Molecular weight: 17.01 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
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| ChTry ESI |
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| ArgC ESI |
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| LysN ESI |
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| TryLysC ESI |
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| Try MALDI |
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| ChTry MALDI |
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| ArgC MALDI |
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| LysN MALDI |
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| TryLysC MALDI |
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| Try LTQ |
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| ChTry LTQ |
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| ArgC LTQ |
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| LysN LTQ |
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| TryLysC LTQ |
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| Try MSlow |
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| ChTry MSlow |
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| ArgC MSlow |
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| LysN MSlow |
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| TryLysC MSlow |
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| Try MShigh |
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| ChTry MShigh |
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| ArgC MShigh |
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| LysN MShigh |
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| TryLysC MShigh |
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General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
0 |
3173 |
162 |
3011 |
1586.5 |
172.08 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
9.36 ± 0.772 | 3.341 ± 0.384 |
3.845 ± 0.879 | 3.719 ± 0.823 |
2.805 ± 0.693 | 8.541 ± 1.134 |
2.175 ± 0.415 | 4.129 ± 1.276 |
3.215 ± 0.329 | 10.148 ± 0.664 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
1.828 ± 0.283 | 2.868 ± 0.448 |
7.091 ± 1.773 | 2.742 ± 0.665 |
6.272 ± 2.134 | 7.28 ± 1.689 |
7.154 ± 0.433 | 8.005 ± 0.009 |
2.364 ± 0.319 | 3.12 ± 1.104 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |