Human papillomavirus 121

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 10

Average proteome isoelectric point is 6.3

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D7P175|D7P175_9PAPI Replication protein E1 OS=Human papillomavirus 121 OX=915429 GN=E1 PE=3 SV=1
MM1 pKa = 7.71IGPEE5 pKa = 4.19SKK7 pKa = 10.94VGDD10 pKa = 3.39IEE12 pKa = 4.31LQLEE16 pKa = 4.51EE17 pKa = 4.98LVMPADD23 pKa = 4.05LLSDD27 pKa = 3.77EE28 pKa = 4.7VLSPDD33 pKa = 3.36EE34 pKa = 4.96DD35 pKa = 3.88EE36 pKa = 5.38EE37 pKa = 4.85EE38 pKa = 4.31EE39 pKa = 5.55LDD41 pKa = 3.77EE42 pKa = 4.04QPYY45 pKa = 10.67RR46 pKa = 11.84IDD48 pKa = 3.52SVCRR52 pKa = 11.84VCKK55 pKa = 9.66TSIRR59 pKa = 11.84FYY61 pKa = 11.4VSASDD66 pKa = 3.19QGIRR70 pKa = 11.84GLQQLLLSQLSFICTRR86 pKa = 11.84CTRR89 pKa = 11.84TSFRR93 pKa = 11.84QNGRR97 pKa = 11.84QQ98 pKa = 3.12

Molecular weight: 11.17 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D7P174|D7P174_9PAPI Protein E7 OS=Human papillomavirus 121 OX=915429 GN=E7 PE=3 SV=1
MM1 pKa = 8.21DD2 pKa = 5.3LQQSPTPVTITEE14 pKa = 4.12YY15 pKa = 11.01CNTFGFSLKK24 pKa = 10.38DD25 pKa = 3.04IRR27 pKa = 11.84LPCTFCRR34 pKa = 11.84FYY36 pKa = 11.08LTIQDD41 pKa = 4.04LASFEE46 pKa = 4.57LKK48 pKa = 10.1QFRR51 pKa = 11.84LLWKK55 pKa = 10.69GPFCYY60 pKa = 10.04ACCRR64 pKa = 11.84SCMRR68 pKa = 11.84LTAAFEE74 pKa = 4.27VRR76 pKa = 11.84KK77 pKa = 9.62HH78 pKa = 4.77YY79 pKa = 10.44QCSCSCLFLEE89 pKa = 5.28DD90 pKa = 3.84LLGRR94 pKa = 11.84PLQHH98 pKa = 7.43IPMRR102 pKa = 11.84CLLCLALLDD111 pKa = 4.08YY112 pKa = 11.19AEE114 pKa = 4.84KK115 pKa = 10.5LQHH118 pKa = 5.67FCVRR122 pKa = 11.84EE123 pKa = 3.91DD124 pKa = 3.67FVLVRR129 pKa = 11.84GNWRR133 pKa = 11.84GYY135 pKa = 9.87CRR137 pKa = 11.84NCIRR141 pKa = 11.84KK142 pKa = 8.45EE143 pKa = 3.81

Molecular weight: 16.94 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2406

98

609

343.7

38.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.32 ± 0.537

2.161 ± 0.673

6.318 ± 0.299

6.276 ± 0.429

4.364 ± 0.38

5.86 ± 0.584

2.078 ± 0.162

5.819 ± 0.668

5.736 ± 0.784

9.185 ± 0.626

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.538 ± 0.295

4.655 ± 0.563

6.027 ± 0.775

4.821 ± 0.176

5.32 ± 0.544

7.357 ± 0.49

6.608 ± 0.647

5.819 ± 0.584

1.33 ± 0.3

3.408 ± 0.555
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski