Amino acid dipepetide frequency for Hubei myriapoda virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.665AlaAla: 4.665 ± 0.896
1.473AlaCys: 1.473 ± 0.259
2.946AlaAsp: 2.946 ± 0.403
3.683AlaGlu: 3.683 ± 0.417
4.419AlaPhe: 4.419 ± 0.316
2.455AlaGly: 2.455 ± 0.643
1.719AlaHis: 1.719 ± 0.379
4.174AlaIle: 4.174 ± 0.656
2.455AlaLys: 2.455 ± 0.278
3.928AlaLeu: 3.928 ± 0.076
1.473AlaMet: 1.473 ± 0.259
2.701AlaAsn: 2.701 ± 0.523
5.892AlaPro: 5.892 ± 0.346
3.683AlaGln: 3.683 ± 0.877
3.928AlaArg: 3.928 ± 1.917
5.156AlaSer: 5.156 ± 0.705
6.384AlaThr: 6.384 ± 2.407
4.419AlaVal: 4.419 ± 0.316
0.737AlaTrp: 0.737 ± 0.101
2.946AlaTyr: 2.946 ± 0.403
0.0AlaXaa: 0.0 ± 0.0
Cys
0.737CysAla: 0.737 ± 0.101
0.737CysCys: 0.737 ± 0.561
1.473CysAsp: 1.473 ± 0.201
0.982CysGlu: 0.982 ± 0.441
0.737CysPhe: 0.737 ± 0.101
0.737CysGly: 0.737 ± 0.101
0.0CysHis: 0.0 ± 0.0
0.491CysIle: 0.491 ± 0.221
1.228CysLys: 1.228 ± 0.139
0.982CysLeu: 0.982 ± 0.479
0.982CysMet: 0.982 ± 0.019
0.737CysAsn: 0.737 ± 0.36
0.982CysPro: 0.982 ± 0.479
0.246CysGln: 0.246 ± 0.12
0.246CysArg: 0.246 ± 0.12
1.964CysSer: 1.964 ± 0.038
0.982CysThr: 0.982 ± 0.019
1.473CysVal: 1.473 ± 0.201
0.0CysTrp: 0.0 ± 0.0
0.246CysTyr: 0.246 ± 0.34
0.0CysXaa: 0.0 ± 0.0
Asp
3.192AspAla: 3.192 ± 1.098
0.982AspCys: 0.982 ± 0.019
5.647AspAsp: 5.647 ± 0.466
4.174AspGlu: 4.174 ± 0.724
3.437AspPhe: 3.437 ± 0.624
3.437AspGly: 3.437 ± 0.163
2.946AspHis: 2.946 ± 0.403
3.683AspIle: 3.683 ± 0.417
2.455AspLys: 2.455 ± 1.198
6.138AspLeu: 6.138 ± 0.686
0.982AspMet: 0.982 ± 0.019
2.455AspAsn: 2.455 ± 0.643
3.683AspPro: 3.683 ± 0.504
1.719AspGln: 1.719 ± 0.082
2.701AspArg: 2.701 ± 1.318
3.192AspSer: 3.192 ± 1.204
2.701AspThr: 2.701 ± 0.858
3.683AspVal: 3.683 ± 0.043
0.982AspTrp: 0.982 ± 0.479
2.946AspTyr: 2.946 ± 0.057
0.0AspXaa: 0.0 ± 0.0
Glu
4.174GluAla: 4.174 ± 1.577
0.737GluCys: 0.737 ± 0.101
5.401GluAsp: 5.401 ± 1.256
5.156GluGlu: 5.156 ± 1.136
3.437GluPhe: 3.437 ± 0.624
1.719GluGly: 1.719 ± 0.379
1.228GluHis: 1.228 ± 0.139
3.928GluIle: 3.928 ± 1.457
3.192GluLys: 3.192 ± 0.177
4.174GluLeu: 4.174 ± 0.656
0.737GluMet: 0.737 ± 0.101
1.473GluAsn: 1.473 ± 0.259
3.437GluPro: 3.437 ± 0.757
1.964GluGln: 1.964 ± 0.038
2.455GluArg: 2.455 ± 0.182
1.964GluSer: 1.964 ± 0.959
4.174GluThr: 4.174 ± 0.196
5.401GluVal: 5.401 ± 0.795
0.737GluTrp: 0.737 ± 0.101
2.21GluTyr: 2.21 ± 1.079
0.0GluXaa: 0.0 ± 0.0
Phe
3.192PheAla: 3.192 ± 0.743
1.228PheCys: 1.228 ± 0.782
2.946PheAsp: 2.946 ± 0.863
3.683PheGlu: 3.683 ± 0.043
2.946PhePhe: 2.946 ± 0.057
2.455PheGly: 2.455 ± 0.182
0.982PheHis: 0.982 ± 0.901
2.455PheIle: 2.455 ± 0.643
2.455PheLys: 2.455 ± 0.278
3.683PheLeu: 3.683 ± 0.964
1.228PheMet: 1.228 ± 0.321
2.946PheAsn: 2.946 ± 0.978
2.701PhePro: 2.701 ± 0.858
1.964PheGln: 1.964 ± 0.038
1.473PheArg: 1.473 ± 0.662
3.683PheSer: 3.683 ± 0.877
2.701PheThr: 2.701 ± 1.318
2.701PheVal: 2.701 ± 0.398
1.473PheTrp: 1.473 ± 0.719
1.964PheTyr: 1.964 ± 0.882
0.0PheXaa: 0.0 ± 0.0
Gly
4.419GlyAla: 4.419 ± 1.065
0.246GlyCys: 0.246 ± 0.12
2.946GlyAsp: 2.946 ± 0.403
2.701GlyGlu: 2.701 ± 0.398
1.964GlyPhe: 1.964 ± 0.038
3.437GlyGly: 3.437 ± 3.385
1.473GlyHis: 1.473 ± 1.122
3.683GlyIle: 3.683 ± 0.504
3.192GlyLys: 3.192 ± 0.177
3.683GlyLeu: 3.683 ± 0.504
0.491GlyMet: 0.491 ± 0.24
1.473GlyAsn: 1.473 ± 0.259
1.473GlyPro: 1.473 ± 1.122
2.946GlyGln: 2.946 ± 0.863
2.21GlyArg: 2.21 ± 0.302
4.174GlySer: 4.174 ± 0.724
2.455GlyThr: 2.455 ± 1.103
5.401GlyVal: 5.401 ± 0.335
0.491GlyTrp: 0.491 ± 0.24
2.21GlyTyr: 2.21 ± 0.618
0.0GlyXaa: 0.0 ± 0.0
His
2.21HisAla: 2.21 ± 0.158
0.491HisCys: 0.491 ± 0.24
1.719HisAsp: 1.719 ± 0.379
0.737HisGlu: 0.737 ± 0.101
2.701HisPhe: 2.701 ± 0.523
2.21HisGly: 2.21 ± 0.302
1.719HisHis: 1.719 ± 0.379
0.982HisIle: 0.982 ± 0.479
1.228HisLys: 1.228 ± 0.599
3.928HisLeu: 3.928 ± 0.076
0.491HisMet: 0.491 ± 0.221
0.246HisAsn: 0.246 ± 0.12
1.964HisPro: 1.964 ± 0.498
0.737HisGln: 0.737 ± 0.36
1.228HisArg: 1.228 ± 0.782
1.473HisSer: 1.473 ± 0.201
0.737HisThr: 0.737 ± 0.101
2.455HisVal: 2.455 ± 0.182
0.982HisTrp: 0.982 ± 0.479
0.737HisTyr: 0.737 ± 0.36
0.0HisXaa: 0.0 ± 0.0
Ile
4.174IleAla: 4.174 ± 0.196
0.491IleCys: 0.491 ± 0.24
2.701IleAsp: 2.701 ± 0.398
1.473IleGlu: 1.473 ± 0.259
2.21IlePhe: 2.21 ± 0.158
3.437IleGly: 3.437 ± 0.624
0.737IleHis: 0.737 ± 0.101
2.455IleIle: 2.455 ± 0.182
2.701IleLys: 2.701 ± 0.858
6.384IleLeu: 6.384 ± 2.195
1.473IleMet: 1.473 ± 0.662
2.21IleAsn: 2.21 ± 0.302
2.946IlePro: 2.946 ± 0.403
2.21IleGln: 2.21 ± 0.302
3.928IleArg: 3.928 ± 0.997
4.174IleSer: 4.174 ± 0.264
2.946IleThr: 2.946 ± 0.863
3.928IleVal: 3.928 ± 0.384
0.737IleTrp: 0.737 ± 0.101
1.719IleTyr: 1.719 ± 0.082
0.0IleXaa: 0.0 ± 0.0
Lys
3.683LysAla: 3.683 ± 0.877
0.737LysCys: 0.737 ± 0.36
3.437LysAsp: 3.437 ± 0.757
2.455LysGlu: 2.455 ± 0.278
2.21LysPhe: 2.21 ± 0.158
1.964LysGly: 1.964 ± 0.959
1.719LysHis: 1.719 ± 0.839
3.192LysIle: 3.192 ± 0.177
2.701LysLys: 2.701 ± 0.858
3.683LysLeu: 3.683 ± 0.877
1.473LysMet: 1.473 ± 0.201
2.455LysAsn: 2.455 ± 0.278
3.437LysPro: 3.437 ± 1.678
2.701LysGln: 2.701 ± 0.398
3.928LysArg: 3.928 ± 0.076
1.964LysSer: 1.964 ± 0.498
3.437LysThr: 3.437 ± 1.217
4.174LysVal: 4.174 ± 1.185
0.737LysTrp: 0.737 ± 0.101
1.473LysTyr: 1.473 ± 0.259
0.0LysXaa: 0.0 ± 0.0
Leu
6.629LeuAla: 6.629 ± 0.474
1.719LeuCys: 1.719 ± 0.082
3.683LeuAsp: 3.683 ± 0.043
4.91LeuGlu: 4.91 ± 1.937
2.701LeuPhe: 2.701 ± 0.523
3.683LeuGly: 3.683 ± 0.417
2.701LeuHis: 2.701 ± 0.398
2.701LeuIle: 2.701 ± 0.858
3.192LeuLys: 3.192 ± 1.098
5.647LeuLeu: 5.647 ± 0.455
1.719LeuMet: 1.719 ± 0.165
3.928LeuAsn: 3.928 ± 0.076
4.419LeuPro: 4.419 ± 0.144
3.192LeuGln: 3.192 ± 1.664
3.192LeuArg: 3.192 ± 1.098
6.629LeuSer: 6.629 ± 0.014
4.419LeuThr: 4.419 ± 0.604
5.647LeuVal: 5.647 ± 0.005
0.737LeuTrp: 0.737 ± 0.101
1.964LeuTyr: 1.964 ± 0.422
0.0LeuXaa: 0.0 ± 0.0
Met
2.455MetAla: 2.455 ± 0.182
0.246MetCys: 0.246 ± 0.34
0.982MetAsp: 0.982 ± 0.441
1.964MetGlu: 1.964 ± 0.038
1.228MetPhe: 1.228 ± 0.599
1.228MetGly: 1.228 ± 0.599
0.246MetHis: 0.246 ± 0.12
1.228MetIle: 1.228 ± 0.599
1.473MetLys: 1.473 ± 0.719
1.719MetLeu: 1.719 ± 0.542
0.246MetMet: 0.246 ± 0.12
1.473MetAsn: 1.473 ± 0.201
2.21MetPro: 2.21 ± 0.302
0.491MetGln: 0.491 ± 0.24
1.964MetArg: 1.964 ± 0.038
0.491MetSer: 0.491 ± 0.24
1.964MetThr: 1.964 ± 0.422
0.491MetVal: 0.491 ± 0.24
0.246MetTrp: 0.246 ± 0.12
0.737MetTyr: 0.737 ± 0.561
0.0MetXaa: 0.0 ± 0.0
Asn
3.192AsnAla: 3.192 ± 0.177
0.491AsnCys: 0.491 ± 0.681
2.701AsnAsp: 2.701 ± 0.858
1.719AsnGlu: 1.719 ± 0.839
3.192AsnPhe: 3.192 ± 0.177
2.946AsnGly: 2.946 ± 0.518
0.737AsnHis: 0.737 ± 0.36
3.683AsnIle: 3.683 ± 0.877
1.719AsnLys: 1.719 ± 0.082
2.21AsnLeu: 2.21 ± 1.079
1.228AsnMet: 1.228 ± 0.091
0.737AsnAsn: 0.737 ± 0.36
2.21AsnPro: 2.21 ± 1.223
1.473AsnGln: 1.473 ± 0.201
1.964AsnArg: 1.964 ± 0.038
2.701AsnSer: 2.701 ± 1.443
2.455AsnThr: 2.455 ± 0.182
3.437AsnVal: 3.437 ± 1.084
0.737AsnTrp: 0.737 ± 0.101
1.473AsnTyr: 1.473 ± 0.662
0.0AsnXaa: 0.0 ± 0.0
Pro
4.419ProAla: 4.419 ± 1.065
0.982ProCys: 0.982 ± 0.441
2.946ProAsp: 2.946 ± 0.863
5.892ProGlu: 5.892 ± 1.956
2.455ProPhe: 2.455 ± 0.182
3.683ProGly: 3.683 ± 0.504
1.228ProHis: 1.228 ± 0.139
3.192ProIle: 3.192 ± 1.204
4.419ProLys: 4.419 ± 0.604
3.683ProLeu: 3.683 ± 0.877
0.491ProMet: 0.491 ± 0.24
2.701ProAsn: 2.701 ± 0.398
5.156ProPro: 5.156 ± 1.165
2.21ProGln: 2.21 ± 0.762
4.665ProArg: 4.665 ± 0.896
4.91ProSer: 4.91 ± 0.365
7.611ProThr: 7.611 ± 0.033
4.665ProVal: 4.665 ± 1.356
1.228ProTrp: 1.228 ± 0.139
1.964ProTyr: 1.964 ± 0.882
0.0ProXaa: 0.0 ± 0.0
Gln
1.719GlnAla: 1.719 ± 0.542
0.982GlnCys: 0.982 ± 0.479
1.964GlnAsp: 1.964 ± 0.882
1.228GlnGlu: 1.228 ± 0.599
0.982GlnPhe: 0.982 ± 0.441
1.228GlnGly: 1.228 ± 0.139
1.473GlnHis: 1.473 ± 0.259
2.946GlnIle: 2.946 ± 0.057
1.719GlnLys: 1.719 ± 0.542
3.437GlnLeu: 3.437 ± 1.544
0.982GlnMet: 0.982 ± 0.019
1.719GlnAsn: 1.719 ± 1.002
3.928GlnPro: 3.928 ± 2.225
2.21GlnGln: 2.21 ± 0.302
1.719GlnArg: 1.719 ± 0.379
2.21GlnSer: 2.21 ± 0.302
3.437GlnThr: 3.437 ± 0.624
2.21GlnVal: 2.21 ± 0.302
0.737GlnTrp: 0.737 ± 0.36
1.473GlnTyr: 1.473 ± 0.259
0.0GlnXaa: 0.0 ± 0.0
Arg
3.928ArgAla: 3.928 ± 1.457
0.737ArgCys: 0.737 ± 0.36
2.946ArgAsp: 2.946 ± 0.518
3.437ArgGlu: 3.437 ± 1.217
2.455ArgPhe: 2.455 ± 0.738
2.21ArgGly: 2.21 ± 1.223
2.701ArgHis: 2.701 ± 0.523
1.719ArgIle: 1.719 ± 0.379
4.174ArgLys: 4.174 ± 1.577
5.401ArgLeu: 5.401 ± 0.335
0.491ArgMet: 0.491 ± 0.24
3.437ArgAsn: 3.437 ± 0.624
4.419ArgPro: 4.419 ± 0.776
2.455ArgGln: 2.455 ± 0.278
2.701ArgArg: 2.701 ± 0.398
3.928ArgSer: 3.928 ± 0.076
4.174ArgThr: 4.174 ± 0.264
2.946ArgVal: 2.946 ± 0.057
0.982ArgTrp: 0.982 ± 0.019
1.228ArgTyr: 1.228 ± 0.139
0.0ArgXaa: 0.0 ± 0.0
Ser
4.419SerAla: 4.419 ± 0.144
0.491SerCys: 0.491 ± 0.221
3.683SerAsp: 3.683 ± 0.964
3.192SerGlu: 3.192 ± 0.743
2.455SerPhe: 2.455 ± 0.278
3.683SerGly: 3.683 ± 0.043
2.946SerHis: 2.946 ± 0.978
4.665SerIle: 4.665 ± 0.485
2.455SerLys: 2.455 ± 0.278
4.174SerLeu: 4.174 ± 0.724
2.455SerMet: 2.455 ± 0.738
3.437SerAsn: 3.437 ± 0.624
5.401SerPro: 5.401 ± 1.256
1.719SerGln: 1.719 ± 0.542
4.419SerArg: 4.419 ± 0.144
5.647SerSer: 5.647 ± 4.148
3.928SerThr: 3.928 ± 0.844
5.401SerVal: 5.401 ± 0.585
1.719SerTrp: 1.719 ± 0.082
2.946SerTyr: 2.946 ± 0.057
0.0SerXaa: 0.0 ± 0.0
Thr
4.419ThrAla: 4.419 ± 1.525
1.473ThrCys: 1.473 ± 0.201
5.156ThrAsp: 5.156 ± 0.245
3.683ThrGlu: 3.683 ± 0.877
3.683ThrPhe: 3.683 ± 0.504
3.192ThrGly: 3.192 ± 1.664
1.473ThrHis: 1.473 ± 0.259
2.946ThrIle: 2.946 ± 0.057
3.683ThrLys: 3.683 ± 0.417
4.419ThrLeu: 4.419 ± 0.776
1.964ThrMet: 1.964 ± 0.422
2.455ThrAsn: 2.455 ± 0.182
5.647ThrPro: 5.647 ± 0.005
1.719ThrGln: 1.719 ± 1.462
5.401ThrArg: 5.401 ± 0.795
5.647ThrSer: 5.647 ± 1.386
6.629ThrThr: 6.629 ± 1.827
3.683ThrVal: 3.683 ± 0.504
0.737ThrTrp: 0.737 ± 0.36
1.719ThrTyr: 1.719 ± 0.082
0.0ThrXaa: 0.0 ± 0.0
Val
4.91ValAla: 4.91 ± 0.365
0.737ValCys: 0.737 ± 0.36
4.174ValAsp: 4.174 ± 0.656
4.91ValGlu: 4.91 ± 1.937
3.683ValPhe: 3.683 ± 0.043
3.683ValGly: 3.683 ± 0.964
1.719ValHis: 1.719 ± 0.379
2.455ValIle: 2.455 ± 0.643
4.665ValLys: 4.665 ± 0.896
2.455ValLeu: 2.455 ± 0.182
1.719ValMet: 1.719 ± 0.082
3.928ValAsn: 3.928 ± 0.537
6.629ValPro: 6.629 ± 0.907
2.455ValGln: 2.455 ± 1.563
4.174ValArg: 4.174 ± 0.264
5.892ValSer: 5.892 ± 1.035
4.419ValThr: 4.419 ± 1.525
5.892ValVal: 5.892 ± 0.575
0.246ValTrp: 0.246 ± 0.34
3.437ValTyr: 3.437 ± 0.297
0.0ValXaa: 0.0 ± 0.0
Trp
0.982TrpAla: 0.982 ± 0.019
0.737TrpCys: 0.737 ± 0.36
1.228TrpAsp: 1.228 ± 0.139
0.0TrpGlu: 0.0 ± 0.0
0.982TrpPhe: 0.982 ± 0.479
0.982TrpGly: 0.982 ± 0.901
0.246TrpHis: 0.246 ± 0.12
0.982TrpIle: 0.982 ± 0.019
0.491TrpLys: 0.491 ± 0.24
0.982TrpLeu: 0.982 ± 0.019
0.737TrpMet: 0.737 ± 0.36
0.246TrpAsn: 0.246 ± 0.12
0.246TrpPro: 0.246 ± 0.34
0.737TrpGln: 0.737 ± 0.101
1.473TrpArg: 1.473 ± 0.259
0.982TrpSer: 0.982 ± 0.019
1.473TrpThr: 1.473 ± 0.259
0.737TrpVal: 0.737 ± 0.36
0.246TrpTrp: 0.246 ± 0.12
0.491TrpTyr: 0.491 ± 0.24
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.719TyrAla: 1.719 ± 0.082
0.246TyrCys: 0.246 ± 0.12
2.455TyrAsp: 2.455 ± 0.738
1.719TyrGlu: 1.719 ± 0.082
0.982TyrPhe: 0.982 ± 0.901
2.701TyrGly: 2.701 ± 0.983
0.982TyrHis: 0.982 ± 0.019
1.473TyrIle: 1.473 ± 1.122
1.964TyrLys: 1.964 ± 0.498
2.701TyrLeu: 2.701 ± 0.398
1.473TyrMet: 1.473 ± 0.719
0.491TyrAsn: 0.491 ± 0.221
1.719TyrPro: 1.719 ± 0.379
1.473TyrGln: 1.473 ± 0.662
2.701TyrArg: 2.701 ± 0.063
2.455TyrSer: 2.455 ± 0.278
2.701TyrThr: 2.701 ± 0.398
3.437TyrVal: 3.437 ± 0.163
0.491TyrTrp: 0.491 ± 0.221
1.719TyrTyr: 1.719 ± 0.542
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (4074 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski