Amino acid dipepetide frequency for Pea enation mosaic virus-1 (strain WSG) (PEMV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.205AlaAla: 8.205 ± 1.683
0.684AlaCys: 0.684 ± 0.449
4.103AlaAsp: 4.103 ± 0.641
3.761AlaGlu: 3.761 ± 0.66
2.393AlaPhe: 2.393 ± 0.982
5.128AlaGly: 5.128 ± 1.23
0.342AlaHis: 0.342 ± 0.224
3.419AlaIle: 3.419 ± 0.478
1.709AlaLys: 1.709 ± 1.026
7.521AlaLeu: 7.521 ± 2.213
0.684AlaMet: 0.684 ± 0.26
2.393AlaAsn: 2.393 ± 0.481
4.786AlaPro: 4.786 ± 0.895
3.419AlaGln: 3.419 ± 0.489
3.419AlaArg: 3.419 ± 1.426
5.47AlaSer: 5.47 ± 0.722
2.393AlaThr: 2.393 ± 1.98
5.128AlaVal: 5.128 ± 1.33
1.026AlaTrp: 1.026 ± 0.49
3.761AlaTyr: 3.761 ± 1.619
0.0AlaXaa: 0.0 ± 0.0
Cys
0.342CysAla: 0.342 ± 0.438
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.393CysGlu: 2.393 ± 0.519
0.0CysPhe: 0.0 ± 0.0
0.342CysGly: 0.342 ± 0.438
0.0CysHis: 0.0 ± 0.0
2.393CysIle: 2.393 ± 1.19
0.342CysLys: 0.342 ± 0.364
1.368CysLeu: 1.368 ± 0.591
0.0CysMet: 0.0 ± 0.0
0.684CysAsn: 0.684 ± 0.26
1.368CysPro: 1.368 ± 0.684
3.077CysGln: 3.077 ± 0.566
0.0CysArg: 0.0 ± 0.0
4.103CysSer: 4.103 ± 0.783
2.393CysThr: 2.393 ± 0.883
0.342CysVal: 0.342 ± 0.224
1.026CysTrp: 1.026 ± 0.94
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.709AspAla: 1.709 ± 0.475
2.393AspCys: 2.393 ± 1.376
2.735AspAsp: 2.735 ± 0.4
2.393AspGlu: 2.393 ± 0.796
3.419AspPhe: 3.419 ± 0.804
2.735AspGly: 2.735 ± 0.408
1.709AspHis: 1.709 ± 0.475
0.342AspIle: 0.342 ± 0.364
0.684AspLys: 0.684 ± 0.26
7.179AspLeu: 7.179 ± 1.58
1.026AspMet: 1.026 ± 0.323
1.709AspAsn: 1.709 ± 0.393
3.419AspPro: 3.419 ± 0.565
3.761AspGln: 3.761 ± 1.272
2.393AspArg: 2.393 ± 1.008
3.761AspSer: 3.761 ± 0.66
4.444AspThr: 4.444 ± 0.817
2.393AspVal: 2.393 ± 1.144
0.342AspTrp: 0.342 ± 0.224
1.026AspTyr: 1.026 ± 0.839
0.0AspXaa: 0.0 ± 0.0
Glu
4.103GluAla: 4.103 ± 1.277
0.684GluCys: 0.684 ± 0.328
4.786GluAsp: 4.786 ± 1.084
5.812GluGlu: 5.812 ± 1.965
1.368GluPhe: 1.368 ± 0.591
2.051GluGly: 2.051 ± 0.978
0.342GluHis: 0.342 ± 0.224
1.709GluIle: 1.709 ± 0.365
3.761GluLys: 3.761 ± 0.91
2.735GluLeu: 2.735 ± 0.739
1.709GluMet: 1.709 ± 0.623
1.026GluAsn: 1.026 ± 0.325
1.368GluPro: 1.368 ± 0.37
1.026GluGln: 1.026 ± 0.81
3.419GluArg: 3.419 ± 0.565
5.812GluSer: 5.812 ± 0.735
4.444GluThr: 4.444 ± 1.393
1.368GluVal: 1.368 ± 0.622
1.026GluTrp: 1.026 ± 0.308
0.342GluTyr: 0.342 ± 0.438
0.0GluXaa: 0.0 ± 0.0
Phe
2.393PheAla: 2.393 ± 0.581
1.709PheCys: 1.709 ± 0.518
2.393PheAsp: 2.393 ± 0.914
0.684PheGlu: 0.684 ± 0.449
1.709PhePhe: 1.709 ± 1.392
2.051PheGly: 2.051 ± 1.039
0.342PheHis: 0.342 ± 0.364
2.051PheIle: 2.051 ± 0.497
0.342PheLys: 0.342 ± 0.364
5.812PheLeu: 5.812 ± 0.754
1.026PheMet: 1.026 ± 0.281
2.051PheAsn: 2.051 ± 0.393
1.368PhePro: 1.368 ± 0.353
0.342PheGln: 0.342 ± 0.364
2.735PheArg: 2.735 ± 0.819
3.419PheSer: 3.419 ± 0.802
2.735PheThr: 2.735 ± 1.025
1.709PheVal: 1.709 ± 0.801
1.709PheTrp: 1.709 ± 0.283
0.342PheTyr: 0.342 ± 0.224
0.0PheXaa: 0.0 ± 0.0
Gly
1.026GlyAla: 1.026 ± 0.428
2.735GlyCys: 2.735 ± 0.569
3.761GlyAsp: 3.761 ± 0.93
2.735GlyGlu: 2.735 ± 0.67
2.735GlyPhe: 2.735 ± 0.813
4.444GlyGly: 4.444 ± 2.534
1.709GlyHis: 1.709 ± 0.647
3.761GlyIle: 3.761 ± 1.03
4.103GlyLys: 4.103 ± 0.995
8.889GlyLeu: 8.889 ± 0.968
0.684GlyMet: 0.684 ± 0.26
1.709GlyAsn: 1.709 ± 1.195
4.444GlyPro: 4.444 ± 1.521
4.103GlyGln: 4.103 ± 1.189
4.444GlyArg: 4.444 ± 0.803
5.47GlySer: 5.47 ± 1.25
4.786GlyThr: 4.786 ± 1.546
4.786GlyVal: 4.786 ± 0.653
2.393GlyTrp: 2.393 ± 0.652
1.709GlyTyr: 1.709 ± 0.639
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.684HisCys: 0.684 ± 0.26
1.368HisAsp: 1.368 ± 0.353
0.342HisGlu: 0.342 ± 0.224
1.026HisPhe: 1.026 ± 0.398
1.709HisGly: 1.709 ± 1.091
0.342HisHis: 0.342 ± 0.438
0.0HisIle: 0.0 ± 0.0
1.026HisLys: 1.026 ± 0.398
2.051HisLeu: 2.051 ± 0.606
1.026HisMet: 1.026 ± 0.673
0.342HisAsn: 0.342 ± 0.224
0.342HisPro: 0.342 ± 0.364
0.684HisGln: 0.684 ± 0.428
2.051HisArg: 2.051 ± 1.116
0.0HisSer: 0.0 ± 0.0
1.368HisThr: 1.368 ± 0.461
2.735HisVal: 2.735 ± 0.598
0.0HisTrp: 0.0 ± 0.0
0.684HisTyr: 0.684 ± 0.601
0.0HisXaa: 0.0 ± 0.0
Ile
3.077IleAla: 3.077 ± 1.333
0.342IleCys: 0.342 ± 0.364
2.051IleAsp: 2.051 ± 0.537
2.051IleGlu: 2.051 ± 0.537
0.684IlePhe: 0.684 ± 0.428
4.103IleGly: 4.103 ± 1.348
1.368IleHis: 1.368 ± 0.52
0.342IleIle: 0.342 ± 0.224
2.051IleLys: 2.051 ± 0.393
6.496IleLeu: 6.496 ± 1.005
0.684IleMet: 0.684 ± 0.26
1.026IleAsn: 1.026 ± 0.308
3.077IlePro: 3.077 ± 0.853
2.735IleGln: 2.735 ± 0.429
3.419IleArg: 3.419 ± 0.65
3.761IleSer: 3.761 ± 0.911
2.735IleThr: 2.735 ± 0.514
3.419IleVal: 3.419 ± 0.375
0.342IleTrp: 0.342 ± 0.438
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.077LysAla: 3.077 ± 1.335
1.709LysCys: 1.709 ± 0.801
2.393LysAsp: 2.393 ± 0.546
1.026LysGlu: 1.026 ± 0.398
2.735LysPhe: 2.735 ± 0.815
5.128LysGly: 5.128 ± 0.913
0.684LysHis: 0.684 ± 0.26
2.393LysIle: 2.393 ± 0.883
4.103LysLys: 4.103 ± 1.114
5.47LysLeu: 5.47 ± 1.442
3.077LysMet: 3.077 ± 1.193
1.026LysAsn: 1.026 ± 0.398
2.393LysPro: 2.393 ± 0.911
2.051LysGln: 2.051 ± 0.98
2.735LysArg: 2.735 ± 0.47
4.103LysSer: 4.103 ± 1.141
3.077LysThr: 3.077 ± 1.24
2.051LysVal: 2.051 ± 0.787
1.709LysTrp: 1.709 ± 0.571
1.026LysTyr: 1.026 ± 0.492
0.0LysXaa: 0.0 ± 0.0
Leu
6.838LeuAla: 6.838 ± 1.672
1.368LeuCys: 1.368 ± 0.726
3.761LeuAsp: 3.761 ± 2.186
4.786LeuGlu: 4.786 ± 1.447
4.444LeuPhe: 4.444 ± 1.094
5.812LeuGly: 5.812 ± 1.209
0.342LeuHis: 0.342 ± 0.438
9.231LeuIle: 9.231 ± 1.281
5.812LeuLys: 5.812 ± 1.168
13.675LeuLeu: 13.675 ± 2.2
1.709LeuMet: 1.709 ± 0.879
2.051LeuAsn: 2.051 ± 0.393
7.521LeuPro: 7.521 ± 1.654
3.419LeuGln: 3.419 ± 1.661
3.419LeuArg: 3.419 ± 0.899
6.838LeuSer: 6.838 ± 1.123
7.179LeuThr: 7.179 ± 1.939
4.444LeuVal: 4.444 ± 1.094
2.735LeuTrp: 2.735 ± 0.721
3.419LeuTyr: 3.419 ± 1.111
0.0LeuXaa: 0.0 ± 0.0
Met
5.128MetAla: 5.128 ± 0.675
0.684MetCys: 0.684 ± 0.26
0.684MetAsp: 0.684 ± 0.562
0.342MetGlu: 0.342 ± 0.224
1.368MetPhe: 1.368 ± 0.52
0.342MetGly: 0.342 ± 0.224
0.342MetHis: 0.342 ± 0.438
0.342MetIle: 0.342 ± 0.364
2.051MetLys: 2.051 ± 0.78
1.026MetLeu: 1.026 ± 0.673
0.684MetMet: 0.684 ± 0.26
1.368MetAsn: 1.368 ± 0.461
1.368MetPro: 1.368 ± 0.724
0.0MetGln: 0.0 ± 0.0
1.368MetArg: 1.368 ± 0.898
0.0MetSer: 0.0 ± 0.0
1.709MetThr: 1.709 ± 0.733
1.026MetVal: 1.026 ± 0.492
0.684MetTrp: 0.684 ± 0.449
0.342MetTyr: 0.342 ± 0.364
0.0MetXaa: 0.0 ± 0.0
Asn
1.368AsnAla: 1.368 ± 1.202
0.342AsnCys: 0.342 ± 0.438
2.393AsnAsp: 2.393 ± 0.879
0.684AsnGlu: 0.684 ± 0.449
1.368AsnPhe: 1.368 ± 0.37
4.444AsnGly: 4.444 ± 1.504
1.368AsnHis: 1.368 ± 0.52
1.026AsnIle: 1.026 ± 0.839
3.077AsnLys: 3.077 ± 0.8
2.735AsnLeu: 2.735 ± 0.806
1.368AsnMet: 1.368 ± 0.505
0.342AsnAsn: 0.342 ± 0.438
0.342AsnPro: 0.342 ± 0.279
2.051AsnGln: 2.051 ± 0.513
1.368AsnArg: 1.368 ± 0.353
1.709AsnSer: 1.709 ± 0.801
0.684AsnThr: 0.684 ± 0.428
0.684AsnVal: 0.684 ± 0.26
1.026AsnTrp: 1.026 ± 0.398
1.709AsnTyr: 1.709 ± 0.639
0.0AsnXaa: 0.0 ± 0.0
Pro
1.368ProAla: 1.368 ± 0.52
0.684ProCys: 0.684 ± 0.26
2.735ProAsp: 2.735 ± 0.857
2.393ProGlu: 2.393 ± 0.652
2.051ProPhe: 2.051 ± 0.513
6.154ProGly: 6.154 ± 0.662
1.368ProHis: 1.368 ± 0.684
2.735ProIle: 2.735 ± 0.514
4.786ProLys: 4.786 ± 1.466
4.786ProLeu: 4.786 ± 0.867
0.684ProMet: 0.684 ± 0.449
1.709ProAsn: 1.709 ± 0.393
7.521ProPro: 7.521 ± 3.913
1.709ProGln: 1.709 ± 0.283
7.179ProArg: 7.179 ± 1.717
7.521ProSer: 7.521 ± 1.241
3.419ProThr: 3.419 ± 0.707
4.103ProVal: 4.103 ± 0.842
1.709ProTrp: 1.709 ± 0.647
0.684ProTyr: 0.684 ± 0.328
0.0ProXaa: 0.0 ± 0.0
Gln
4.444GlnAla: 4.444 ± 1.039
1.368GlnCys: 1.368 ± 0.461
3.419GlnAsp: 3.419 ± 1.037
1.709GlnGlu: 1.709 ± 0.475
1.368GlnPhe: 1.368 ± 0.461
2.393GlnGly: 2.393 ± 0.883
0.342GlnHis: 0.342 ± 0.224
1.709GlnIle: 1.709 ± 0.393
3.077GlnLys: 3.077 ± 0.914
2.735GlnLeu: 2.735 ± 0.806
0.0GlnMet: 0.0 ± 0.0
0.684GlnAsn: 0.684 ± 0.328
3.077GlnPro: 3.077 ± 1.583
1.368GlnGln: 1.368 ± 0.52
2.735GlnArg: 2.735 ± 0.569
7.521GlnSer: 7.521 ± 0.868
2.051GlnThr: 2.051 ± 0.606
1.368GlnVal: 1.368 ± 0.487
0.0GlnTrp: 0.0 ± 0.0
0.342GlnTyr: 0.342 ± 0.224
0.0GlnXaa: 0.0 ± 0.0
Arg
4.444ArgAla: 4.444 ± 1.044
1.709ArgCys: 1.709 ± 0.393
1.709ArgAsp: 1.709 ± 0.518
3.761ArgGlu: 3.761 ± 0.324
3.077ArgPhe: 3.077 ± 0.549
4.444ArgGly: 4.444 ± 1.695
1.026ArgHis: 1.026 ± 0.325
3.077ArgIle: 3.077 ± 1.5
3.761ArgLys: 3.761 ± 0.932
2.735ArgLeu: 2.735 ± 1.448
1.026ArgMet: 1.026 ± 0.428
3.761ArgAsn: 3.761 ± 1.111
6.154ArgPro: 6.154 ± 0.891
1.026ArgGln: 1.026 ± 0.524
8.547ArgArg: 8.547 ± 4.182
7.179ArgSer: 7.179 ± 1.971
4.786ArgThr: 4.786 ± 1.109
3.077ArgVal: 3.077 ± 0.701
0.342ArgTrp: 0.342 ± 0.224
1.368ArgTyr: 1.368 ± 0.898
0.0ArgXaa: 0.0 ± 0.0
Ser
6.838SerAla: 6.838 ± 0.328
1.709SerCys: 1.709 ± 0.801
4.444SerAsp: 4.444 ± 0.818
4.103SerGlu: 4.103 ± 0.827
3.419SerPhe: 3.419 ± 0.566
7.521SerGly: 7.521 ± 1.508
2.051SerHis: 2.051 ± 0.393
5.128SerIle: 5.128 ± 0.88
3.077SerLys: 3.077 ± 0.561
7.521SerLeu: 7.521 ± 1.349
2.051SerMet: 2.051 ± 1.677
3.077SerAsn: 3.077 ± 1.187
5.128SerPro: 5.128 ± 1.243
4.786SerGln: 4.786 ± 1.97
6.838SerArg: 6.838 ± 0.556
9.915SerSer: 9.915 ± 1.155
5.128SerThr: 5.128 ± 0.281
5.47SerVal: 5.47 ± 0.885
2.393SerTrp: 2.393 ± 0.872
3.077SerTyr: 3.077 ± 1.39
0.0SerXaa: 0.0 ± 0.0
Thr
4.786ThrAla: 4.786 ± 1.211
0.684ThrCys: 0.684 ± 0.26
3.419ThrAsp: 3.419 ± 0.874
3.761ThrGlu: 3.761 ± 1.027
2.735ThrPhe: 2.735 ± 0.806
5.47ThrGly: 5.47 ± 0.858
1.026ThrHis: 1.026 ± 0.836
1.368ThrIle: 1.368 ± 0.52
2.735ThrLys: 2.735 ± 0.47
4.103ThrLeu: 4.103 ± 0.957
1.368ThrMet: 1.368 ± 0.331
1.368ThrAsn: 1.368 ± 0.591
5.128ThrPro: 5.128 ± 1.764
1.026ThrGln: 1.026 ± 0.492
2.051ThrArg: 2.051 ± 0.445
8.205ThrSer: 8.205 ± 0.666
5.128ThrThr: 5.128 ± 0.771
4.103ThrVal: 4.103 ± 1.169
4.444ThrTrp: 4.444 ± 1.023
1.368ThrTyr: 1.368 ± 0.52
0.0ThrXaa: 0.0 ± 0.0
Val
5.47ValAla: 5.47 ± 0.944
0.684ValCys: 0.684 ± 0.26
2.735ValAsp: 2.735 ± 0.946
2.735ValGlu: 2.735 ± 0.6
0.684ValPhe: 0.684 ± 0.449
2.735ValGly: 2.735 ± 0.4
2.051ValHis: 2.051 ± 0.986
1.709ValIle: 1.709 ± 0.475
4.444ValLys: 4.444 ± 0.866
5.812ValLeu: 5.812 ± 1.6
0.342ValMet: 0.342 ± 0.364
1.709ValAsn: 1.709 ± 0.571
4.103ValPro: 4.103 ± 0.573
2.393ValGln: 2.393 ± 0.985
3.761ValArg: 3.761 ± 0.842
3.761ValSer: 3.761 ± 0.467
2.393ValThr: 2.393 ± 0.883
5.47ValVal: 5.47 ± 2.676
1.368ValTrp: 1.368 ± 0.461
3.077ValTyr: 3.077 ± 0.413
0.0ValXaa: 0.0 ± 0.0
Trp
3.077TrpAla: 3.077 ± 0.549
0.0TrpCys: 0.0 ± 0.0
1.026TrpAsp: 1.026 ± 0.308
1.026TrpGlu: 1.026 ± 0.428
0.0TrpPhe: 0.0 ± 0.0
2.393TrpGly: 2.393 ± 1.246
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.342TrpLys: 0.342 ± 0.224
3.761TrpLeu: 3.761 ± 0.428
0.342TrpMet: 0.342 ± 0.438
1.368TrpAsn: 1.368 ± 0.461
2.393TrpPro: 2.393 ± 0.883
1.026TrpGln: 1.026 ± 0.308
0.342TrpArg: 0.342 ± 0.364
2.735TrpSer: 2.735 ± 1.025
2.393TrpThr: 2.393 ± 0.652
1.026TrpVal: 1.026 ± 0.398
0.0TrpTrp: 0.0 ± 0.0
1.709TrpTyr: 1.709 ± 0.632
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.051TyrAla: 2.051 ± 0.708
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.393TyrGlu: 2.393 ± 0.546
0.342TyrPhe: 0.342 ± 0.364
1.026TyrGly: 1.026 ± 0.481
1.026TyrHis: 1.026 ± 0.82
1.026TyrIle: 1.026 ± 0.308
0.684TyrLys: 0.684 ± 0.328
2.393TyrLeu: 2.393 ± 1.083
1.026TyrMet: 1.026 ± 0.398
0.684TyrAsn: 0.684 ± 0.728
0.0TyrPro: 0.0 ± 0.0
1.709TyrGln: 1.709 ± 1.076
4.786TyrArg: 4.786 ± 1.442
2.393TyrSer: 2.393 ± 0.659
1.026TyrThr: 1.026 ± 0.839
2.735TyrVal: 2.735 ± 0.985
0.684TyrTrp: 0.684 ± 0.562
0.684TyrTyr: 0.684 ± 0.876
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2926 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski