Gorilla gorilla gorilla (Western lowland gorilla)
Average proteome isoelectric point is 6.7
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 44727 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A2I2Z1I1|A0A2I2Z1I1_GORGO Isoform of G3SBN6 Mitochondrial rRNA methyltransferase 2 OS=Gorilla gorilla gorilla OX=9595 GN=MRM2 PE=3 SV=1
NN1 pKa = 6.04 TCRR4 pKa = 11.84 NSFPLPEE11 pKa = 4.43 PAEE14 pKa = 4.04 GHH16 pKa = 5.8 LLKK19 pKa = 11.02 VLLTGTLYY27 pKa = 10.43 IADD30 pKa = 4.21 SHH32 pKa = 6.84 LSWLDD37 pKa = 3.26 SSGLGFSLEE46 pKa = 4.13 YY47 pKa = 8.63 TTISLLALSRR57 pKa = 11.84 DD58 pKa = 3.5 QSDD61 pKa = 3.73 CLGEE65 pKa = 3.96 HH66 pKa = 7.0 LYY68 pKa = 11.72 VMVSDD73 pKa = 4.16 KK74 pKa = 11.2 FEE76 pKa = 3.91 EE77 pKa = 4.53 SKK79 pKa = 11.17 EE80 pKa = 4.19 SVADD84 pKa = 3.91 EE85 pKa = 4.42 EE86 pKa = 5.45 EE87 pKa = 4.15 EE88 pKa = 5.06 DD89 pKa = 3.81 SDD91 pKa = 4.55 DD92 pKa = 3.97 VEE94 pKa = 5.51 LIAEE98 pKa = 4.96 FIFVPSDD105 pKa = 3.16 KK106 pKa = 10.74 SALGAMFTAMCEE118 pKa = 4.33 CQALHH123 pKa = 7.39 PDD125 pKa = 4.27 PEE127 pKa = 6.1 DD128 pKa = 4.01 EE129 pKa = 6.61 DD130 pKa = 4.47 EE131 pKa = 5.14 DD132 pKa = 6.1 DD133 pKa = 4.31 YY134 pKa = 12.03 DD135 pKa = 4.8 GEE137 pKa = 4.23 EE138 pKa = 4.52 HH139 pKa = 7.25 DD140 pKa = 4.91 VEE142 pKa = 4.85 VDD144 pKa = 3.4 TTPTVAGQFEE154 pKa = 4.72 DD155 pKa = 3.71 TDD157 pKa = 3.5 VDD159 pKa = 3.87 HH160 pKa = 7.41
Molecular weight: 17.73 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.708
IPC2_protein 3.719
IPC_protein 3.706
Toseland 3.503
ProMoST 3.859
Dawson 3.694
Bjellqvist 3.846
Wikipedia 3.605
Rodwell 3.541
Grimsley 3.414
Solomon 3.681
Lehninger 3.643
Nozaki 3.808
DTASelect 4.012
Thurlkill 3.554
EMBOSS 3.617
Sillero 3.834
Patrickios 1.1
IPC_peptide 3.681
IPC2_peptide 3.808
IPC2.peptide.svr19 3.739
Protein with the highest isoelectric point:
>tr|A0A2I2YT43|A0A2I2YT43_GORGO NYN domain and retroviral integrase containing OS=Gorilla gorilla gorilla OX=9595 GN=NYNRIN PE=4 SV=1
MM1 pKa = 7.1 RR2 pKa = 11.84 AKK4 pKa = 9.12 WRR6 pKa = 11.84 KK7 pKa = 9.1 KK8 pKa = 9.32 RR9 pKa = 11.84 MRR11 pKa = 11.84 RR12 pKa = 11.84 LKK14 pKa = 10.08 RR15 pKa = 11.84 KK16 pKa = 8.21 RR17 pKa = 11.84 RR18 pKa = 11.84 KK19 pKa = 8.46 MRR21 pKa = 11.84 QRR23 pKa = 11.84 SKK25 pKa = 11.41
Molecular weight: 3.46 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.517
IPC2_protein 11.213
IPC_protein 12.793
Toseland 12.969
ProMoST 13.451
Dawson 12.969
Bjellqvist 12.954
Wikipedia 13.437
Rodwell 12.705
Grimsley 12.998
Solomon 13.451
Lehninger 13.364
Nozaki 12.969
DTASelect 12.954
Thurlkill 12.969
EMBOSS 13.466
Sillero 12.969
Patrickios 12.427
IPC_peptide 13.466
IPC2_peptide 12.442
IPC2.peptide.svr19 9.142
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
21789
22938
44727
23270229
12
34213
520.3
58.05
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.857 ± 0.012
2.215 ± 0.01
4.86 ± 0.006
7.22 ± 0.017
3.625 ± 0.008
6.443 ± 0.015
2.596 ± 0.007
4.453 ± 0.01
5.9 ± 0.017
9.882 ± 0.018
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.184 ± 0.005
3.683 ± 0.008
6.143 ± 0.018
4.805 ± 0.012
5.6 ± 0.01
8.277 ± 0.016
5.332 ± 0.012
6.016 ± 0.013
1.214 ± 0.004
2.665 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here