Amino acid dipepetide frequency for Potato virus Y (strain N) (PVY)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.188AlaAla: 5.188 ± 0.923
0.741AlaCys: 0.741 ± 0.357
3.211AlaAsp: 3.211 ± 0.081
3.458AlaGlu: 3.458 ± 0.2
1.976AlaPhe: 1.976 ± 0.952
2.717AlaGly: 2.717 ± 0.157
2.717AlaHis: 2.717 ± 0.157
1.976AlaIle: 1.976 ± 0.026
4.941AlaLys: 4.941 ± 0.553
6.67AlaLeu: 6.67 ± 0.28
2.223AlaMet: 2.223 ± 0.395
2.964AlaAsn: 2.964 ± 0.038
2.47AlaPro: 2.47 ± 0.276
4.694AlaGln: 4.694 ± 0.183
4.447AlaArg: 4.447 ± 1.28
4.941AlaSer: 4.941 ± 0.553
4.941AlaThr: 4.941 ± 0.553
3.706AlaVal: 3.706 ± 0.807
0.494AlaTrp: 0.494 ± 0.238
3.706AlaTyr: 3.706 ± 0.807
0.0AlaXaa: 0.0 ± 0.0
Cys
1.482CysAla: 1.482 ± 0.264
1.235CysCys: 1.235 ± 0.383
2.964CysAsp: 2.964 ± 0.527
0.741CysGlu: 0.741 ± 0.132
0.741CysPhe: 0.741 ± 0.132
0.741CysGly: 0.741 ± 0.132
0.741CysHis: 0.741 ± 0.132
0.494CysIle: 0.494 ± 0.238
1.235CysLys: 1.235 ± 0.106
1.482CysLeu: 1.482 ± 0.264
0.494CysMet: 0.494 ± 0.238
0.247CysAsn: 0.247 ± 0.119
0.494CysPro: 0.494 ± 0.251
0.247CysGln: 0.247 ± 0.119
0.494CysArg: 0.494 ± 0.238
0.247CysSer: 0.247 ± 0.119
1.235CysThr: 1.235 ± 0.383
2.223CysVal: 2.223 ± 0.093
0.247CysTrp: 0.247 ± 0.119
0.988CysTyr: 0.988 ± 0.502
0.0CysXaa: 0.0 ± 0.0
Asp
5.435AspAla: 5.435 ± 0.315
0.988AspCys: 0.988 ± 0.013
2.47AspAsp: 2.47 ± 0.212
2.964AspGlu: 2.964 ± 0.45
3.458AspPhe: 3.458 ± 0.688
4.447AspGly: 4.447 ± 0.302
1.235AspHis: 1.235 ± 0.383
3.953AspIle: 3.953 ± 0.926
3.211AspLys: 3.211 ± 0.081
5.929AspLeu: 5.929 ± 0.566
1.235AspMet: 1.235 ± 0.383
2.47AspAsn: 2.47 ± 0.276
2.223AspPro: 2.223 ± 0.395
0.988AspGln: 0.988 ± 0.013
2.223AspArg: 2.223 ± 0.093
2.47AspSer: 2.47 ± 0.276
3.211AspThr: 3.211 ± 0.569
3.458AspVal: 3.458 ± 1.177
0.741AspTrp: 0.741 ± 0.357
1.235AspTyr: 1.235 ± 0.106
0.0AspXaa: 0.0 ± 0.0
Glu
2.47GluAla: 2.47 ± 1.19
1.976GluCys: 1.976 ± 0.026
2.223GluAsp: 2.223 ± 0.093
4.941GluGlu: 4.941 ± 0.914
2.223GluPhe: 2.223 ± 0.582
2.47GluGly: 2.47 ± 0.276
2.47GluHis: 2.47 ± 0.212
4.447GluIle: 4.447 ± 0.676
3.706GluLys: 3.706 ± 0.17
5.682GluLeu: 5.682 ± 0.196
1.976GluMet: 1.976 ± 0.463
3.211GluAsn: 3.211 ± 1.058
2.223GluPro: 2.223 ± 0.395
1.482GluGln: 1.482 ± 0.714
5.188GluArg: 5.188 ± 0.434
2.47GluSer: 2.47 ± 0.276
2.223GluThr: 2.223 ± 0.093
2.717GluVal: 2.717 ± 0.82
0.741GluTrp: 0.741 ± 0.132
2.964GluTyr: 2.964 ± 0.45
0.0GluXaa: 0.0 ± 0.0
Phe
2.47PheAla: 2.47 ± 0.212
0.0PheCys: 0.0 ± 0.0
1.976PheAsp: 1.976 ± 0.952
3.706PheGlu: 3.706 ± 0.17
3.458PhePhe: 3.458 ± 0.289
3.211PheGly: 3.211 ± 0.081
0.247PheHis: 0.247 ± 0.119
1.976PheIle: 1.976 ± 0.026
3.953PheLys: 3.953 ± 0.051
2.964PheLeu: 2.964 ± 0.527
0.741PheMet: 0.741 ± 0.357
2.47PheAsn: 2.47 ± 0.276
1.482PhePro: 1.482 ± 0.225
1.482PheGln: 1.482 ± 0.264
4.941PheArg: 4.941 ± 0.064
2.717PheSer: 2.717 ± 0.331
2.964PheThr: 2.964 ± 0.45
2.717PheVal: 2.717 ± 0.82
0.741PheTrp: 0.741 ± 0.132
1.976PheTyr: 1.976 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
2.47GlyAla: 2.47 ± 0.212
0.988GlyCys: 0.988 ± 0.476
3.211GlyAsp: 3.211 ± 1.386
1.235GlyGlu: 1.235 ± 0.106
2.47GlyPhe: 2.47 ± 0.212
3.706GlyGly: 3.706 ± 0.659
1.482GlyHis: 1.482 ± 0.225
3.706GlyIle: 3.706 ± 0.17
3.211GlyLys: 3.211 ± 0.569
7.164GlyLeu: 7.164 ± 0.518
0.741GlyMet: 0.741 ± 0.357
3.211GlyAsn: 3.211 ± 0.408
0.741GlyPro: 0.741 ± 0.132
1.482GlyGln: 1.482 ± 0.752
2.964GlyArg: 2.964 ± 0.038
6.67GlySer: 6.67 ± 0.28
3.953GlyThr: 3.953 ± 0.438
3.953GlyVal: 3.953 ± 0.051
0.247GlyTrp: 0.247 ± 0.119
1.729GlyTyr: 1.729 ± 0.633
0.0GlyXaa: 0.0 ± 0.0
His
1.482HisAla: 1.482 ± 0.264
0.494HisCys: 0.494 ± 0.251
1.729HisAsp: 1.729 ± 0.145
1.482HisGlu: 1.482 ± 0.264
2.717HisPhe: 2.717 ± 0.331
0.988HisGly: 0.988 ± 0.476
0.741HisHis: 0.741 ± 0.357
1.729HisIle: 1.729 ± 0.633
0.741HisLys: 0.741 ± 0.621
3.706HisLeu: 3.706 ± 0.659
0.494HisMet: 0.494 ± 0.251
0.494HisAsn: 0.494 ± 0.238
0.741HisPro: 0.741 ± 0.132
1.729HisGln: 1.729 ± 0.833
0.741HisArg: 0.741 ± 0.132
1.729HisSer: 1.729 ± 0.145
2.717HisThr: 2.717 ± 0.331
1.976HisVal: 1.976 ± 0.514
0.247HisTrp: 0.247 ± 0.119
1.235HisTyr: 1.235 ± 0.106
0.0HisXaa: 0.0 ± 0.0
Ile
4.941IleAla: 4.941 ± 0.064
0.988IleCys: 0.988 ± 0.013
3.706IleAsp: 3.706 ± 0.807
4.447IleGlu: 4.447 ± 1.164
2.964IlePhe: 2.964 ± 0.527
2.964IleGly: 2.964 ± 0.038
1.976IleHis: 1.976 ± 0.514
3.706IleIle: 3.706 ± 0.17
4.694IleLys: 4.694 ± 0.183
6.67IleLeu: 6.67 ± 1.675
2.964IleMet: 2.964 ± 0.837
2.47IleAsn: 2.47 ± 0.765
1.729IlePro: 1.729 ± 0.833
3.458IleGln: 3.458 ± 0.2
2.717IleArg: 2.717 ± 0.331
3.953IleSer: 3.953 ± 0.051
1.729IleThr: 1.729 ± 0.633
4.447IleVal: 4.447 ± 0.676
0.494IleTrp: 0.494 ± 0.238
0.247IleTyr: 0.247 ± 0.119
0.0IleXaa: 0.0 ± 0.0
Lys
3.458LysAla: 3.458 ± 0.2
0.988LysCys: 0.988 ± 0.013
5.435LysAsp: 5.435 ± 0.663
2.964LysGlu: 2.964 ± 0.45
2.47LysPhe: 2.47 ± 0.212
8.152LysGly: 8.152 ± 0.472
2.964LysHis: 2.964 ± 0.527
2.47LysIle: 2.47 ± 0.276
6.423LysLys: 6.423 ± 0.816
8.152LysLeu: 8.152 ± 1.45
1.235LysMet: 1.235 ± 0.106
4.694LysAsn: 4.694 ± 0.183
1.729LysPro: 1.729 ± 0.833
4.2LysGln: 4.2 ± 1.399
2.223LysArg: 2.223 ± 0.884
4.2LysSer: 4.2 ± 0.068
3.211LysThr: 3.211 ± 0.408
3.706LysVal: 3.706 ± 0.319
0.494LysTrp: 0.494 ± 0.251
1.976LysTyr: 1.976 ± 0.463
0.0LysXaa: 0.0 ± 0.0
Leu
5.929LeuAla: 5.929 ± 1.054
0.247LeuCys: 0.247 ± 0.119
6.423LeuAsp: 6.423 ± 0.161
6.176LeuGlu: 6.176 ± 0.935
3.706LeuPhe: 3.706 ± 0.659
4.2LeuGly: 4.2 ± 0.421
1.976LeuHis: 1.976 ± 0.026
6.67LeuIle: 6.67 ± 0.28
7.658LeuLys: 7.658 ± 0.267
9.14LeuLeu: 9.14 ± 0.974
2.964LeuMet: 2.964 ± 0.038
4.447LeuAsn: 4.447 ± 0.791
4.941LeuPro: 4.941 ± 0.553
2.47LeuGln: 2.47 ± 0.212
5.435LeuArg: 5.435 ± 1.152
7.164LeuSer: 7.164 ± 1.437
3.953LeuThr: 3.953 ± 0.438
4.2LeuVal: 4.2 ± 0.068
1.729LeuTrp: 1.729 ± 0.145
2.717LeuTyr: 2.717 ± 0.157
0.0LeuXaa: 0.0 ± 0.0
Met
3.211MetAla: 3.211 ± 0.408
0.494MetCys: 0.494 ± 0.251
1.235MetAsp: 1.235 ± 0.106
1.729MetGlu: 1.729 ± 0.344
0.494MetPhe: 0.494 ± 0.238
1.235MetGly: 1.235 ± 0.106
1.235MetHis: 1.235 ± 0.595
1.235MetIle: 1.235 ± 0.383
1.729MetLys: 1.729 ± 0.344
1.729MetLeu: 1.729 ± 0.145
1.729MetMet: 1.729 ± 0.124
0.741MetAsn: 0.741 ± 0.132
1.235MetPro: 1.235 ± 0.595
0.988MetGln: 0.988 ± 0.476
3.458MetArg: 3.458 ± 0.778
1.976MetSer: 1.976 ± 0.514
0.988MetThr: 0.988 ± 0.476
2.223MetVal: 2.223 ± 0.582
0.494MetTrp: 0.494 ± 0.251
1.235MetTyr: 1.235 ± 0.106
0.0MetXaa: 0.0 ± 0.0
Asn
2.964AsnAla: 2.964 ± 0.038
0.247AsnCys: 0.247 ± 0.119
1.729AsnAsp: 1.729 ± 0.344
3.211AsnGlu: 3.211 ± 0.081
2.964AsnPhe: 2.964 ± 0.527
3.211AsnGly: 3.211 ± 0.569
0.741AsnHis: 0.741 ± 0.132
2.964AsnIle: 2.964 ± 0.038
2.964AsnLys: 2.964 ± 0.45
5.435AsnLeu: 5.435 ± 0.315
0.988AsnMet: 0.988 ± 0.476
2.47AsnAsn: 2.47 ± 0.212
1.482AsnPro: 1.482 ± 0.714
1.235AsnGln: 1.235 ± 0.383
2.223AsnArg: 2.223 ± 0.395
1.976AsnSer: 1.976 ± 0.026
2.717AsnThr: 2.717 ± 0.157
2.223AsnVal: 2.223 ± 0.093
1.235AsnTrp: 1.235 ± 0.383
1.729AsnTyr: 1.729 ± 0.344
0.0AsnXaa: 0.0 ± 0.0
Pro
1.976ProAla: 1.976 ± 0.514
0.988ProCys: 0.988 ± 0.502
0.988ProAsp: 0.988 ± 0.013
1.729ProGlu: 1.729 ± 0.344
2.47ProPhe: 2.47 ± 0.276
1.482ProGly: 1.482 ± 0.752
0.741ProHis: 0.741 ± 0.357
1.976ProIle: 1.976 ± 0.463
2.964ProLys: 2.964 ± 0.527
2.47ProLeu: 2.47 ± 0.701
0.0ProMet: 0.0 ± 0.0
1.482ProAsn: 1.482 ± 0.225
1.235ProPro: 1.235 ± 0.383
1.729ProGln: 1.729 ± 0.344
2.47ProArg: 2.47 ± 0.276
3.953ProSer: 3.953 ± 0.54
4.2ProThr: 4.2 ± 0.068
3.706ProVal: 3.706 ± 0.319
0.0ProTrp: 0.0 ± 0.0
1.976ProTyr: 1.976 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
3.458GlnAla: 3.458 ± 0.688
0.0GlnCys: 0.0 ± 0.0
0.247GlnAsp: 0.247 ± 0.119
1.482GlnGlu: 1.482 ± 0.714
2.964GlnPhe: 2.964 ± 0.939
1.235GlnGly: 1.235 ± 0.106
0.741GlnHis: 0.741 ± 0.132
3.706GlnIle: 3.706 ± 0.17
2.964GlnLys: 2.964 ± 1.016
3.458GlnLeu: 3.458 ± 0.778
2.47GlnMet: 2.47 ± 0.276
0.741GlnAsn: 0.741 ± 0.357
1.729GlnPro: 1.729 ± 0.344
2.223GlnGln: 2.223 ± 0.093
2.717GlnArg: 2.717 ± 0.646
2.964GlnSer: 2.964 ± 0.45
1.482GlnThr: 1.482 ± 0.264
2.964GlnVal: 2.964 ± 0.038
0.247GlnTrp: 0.247 ± 0.119
0.988GlnTyr: 0.988 ± 0.502
0.0GlnXaa: 0.0 ± 0.0
Arg
3.211ArgAla: 3.211 ± 0.569
0.988ArgCys: 0.988 ± 0.502
2.964ArgAsp: 2.964 ± 0.45
3.211ArgGlu: 3.211 ± 0.408
3.211ArgPhe: 3.211 ± 0.897
3.211ArgGly: 3.211 ± 0.408
1.482ArgHis: 1.482 ± 0.225
3.953ArgIle: 3.953 ± 0.54
4.941ArgLys: 4.941 ± 1.042
4.2ArgLeu: 4.2 ± 0.068
2.223ArgMet: 2.223 ± 0.093
1.976ArgAsn: 1.976 ± 0.026
1.976ArgPro: 1.976 ± 0.514
2.223ArgGln: 2.223 ± 0.093
3.211ArgArg: 3.211 ± 0.081
3.706ArgSer: 3.706 ± 0.319
4.2ArgThr: 4.2 ± 0.068
3.953ArgVal: 3.953 ± 1.517
0.0ArgTrp: 0.0 ± 0.0
2.223ArgTyr: 2.223 ± 0.093
0.0ArgXaa: 0.0 ± 0.0
Ser
6.423SerAla: 6.423 ± 1.305
1.235SerCys: 1.235 ± 0.383
2.47SerAsp: 2.47 ± 0.276
4.447SerGlu: 4.447 ± 0.302
2.47SerPhe: 2.47 ± 0.276
3.211SerGly: 3.211 ± 0.408
0.988SerHis: 0.988 ± 0.013
6.423SerIle: 6.423 ± 0.816
4.694SerLys: 4.694 ± 0.672
6.423SerLeu: 6.423 ± 0.65
2.47SerMet: 2.47 ± 0.701
2.717SerAsn: 2.717 ± 0.157
3.458SerPro: 3.458 ± 0.289
2.717SerGln: 2.717 ± 0.331
1.235SerArg: 1.235 ± 0.106
4.941SerSer: 4.941 ± 0.914
5.188SerThr: 5.188 ± 1.033
5.435SerVal: 5.435 ± 0.315
0.988SerTrp: 0.988 ± 0.476
1.976SerTyr: 1.976 ± 0.026
0.0SerXaa: 0.0 ± 0.0
Thr
2.717ThrAla: 2.717 ± 0.157
3.458ThrCys: 3.458 ± 1.267
3.211ThrAsp: 3.211 ± 0.408
4.2ThrGlu: 4.2 ± 1.045
2.223ThrPhe: 2.223 ± 0.093
1.729ThrGly: 1.729 ± 0.344
1.482ThrHis: 1.482 ± 0.264
3.706ThrIle: 3.706 ± 0.17
3.211ThrLys: 3.211 ± 0.081
4.2ThrLeu: 4.2 ± 0.557
1.235ThrMet: 1.235 ± 0.106
1.729ThrAsn: 1.729 ± 0.833
2.47ThrPro: 2.47 ± 0.701
2.717ThrGln: 2.717 ± 0.157
2.47ThrArg: 2.47 ± 0.212
4.2ThrSer: 4.2 ± 0.557
4.447ThrThr: 4.447 ± 0.791
4.2ThrVal: 4.2 ± 1.045
1.729ThrTrp: 1.729 ± 0.145
1.976ThrTyr: 1.976 ± 0.514
0.0ThrXaa: 0.0 ± 0.0
Val
5.682ValAla: 5.682 ± 0.782
1.482ValCys: 1.482 ± 0.714
5.682ValAsp: 5.682 ± 0.196
3.458ValGlu: 3.458 ± 1.177
1.729ValPhe: 1.729 ± 0.344
3.458ValGly: 3.458 ± 0.688
2.223ValHis: 2.223 ± 0.395
2.964ValIle: 2.964 ± 0.527
4.694ValLys: 4.694 ± 0.795
4.2ValLeu: 4.2 ± 0.068
1.729ValMet: 1.729 ± 0.344
2.47ValAsn: 2.47 ± 0.701
2.717ValPro: 2.717 ± 0.646
2.223ValGln: 2.223 ± 0.093
4.941ValArg: 4.941 ± 0.553
5.682ValSer: 5.682 ± 0.293
2.223ValThr: 2.223 ± 0.582
5.929ValVal: 5.929 ± 0.901
0.494ValTrp: 0.494 ± 0.238
1.976ValTyr: 1.976 ± 0.463
0.0ValXaa: 0.0 ± 0.0
Trp
0.494TrpAla: 0.494 ± 0.251
0.494TrpCys: 0.494 ± 0.238
1.235TrpAsp: 1.235 ± 0.595
0.247TrpGlu: 0.247 ± 0.119
0.494TrpPhe: 0.494 ± 0.238
0.988TrpGly: 0.988 ± 0.013
0.0TrpHis: 0.0 ± 0.0
0.741TrpIle: 0.741 ± 0.132
0.988TrpLys: 0.988 ± 0.013
0.494TrpLeu: 0.494 ± 0.238
0.247TrpMet: 0.247 ± 0.119
0.988TrpAsn: 0.988 ± 0.013
0.494TrpPro: 0.494 ± 0.251
0.494TrpGln: 0.494 ± 0.251
0.247TrpArg: 0.247 ± 0.119
0.494TrpSer: 0.494 ± 0.251
0.741TrpThr: 0.741 ± 0.132
0.988TrpVal: 0.988 ± 0.476
0.247TrpTrp: 0.247 ± 0.119
0.494TrpTyr: 0.494 ± 0.251
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.717TyrAla: 2.717 ± 0.331
0.741TyrCys: 0.741 ± 0.132
1.235TyrAsp: 1.235 ± 0.106
1.976TyrGlu: 1.976 ± 0.463
0.988TyrPhe: 0.988 ± 0.476
1.976TyrGly: 1.976 ± 0.952
1.729TyrHis: 1.729 ± 0.633
2.47TyrIle: 2.47 ± 0.212
2.223TyrLys: 2.223 ± 0.395
1.976TyrLeu: 1.976 ± 0.026
1.235TyrMet: 1.235 ± 0.106
2.717TyrAsn: 2.717 ± 0.331
2.964TyrPro: 2.964 ± 1.016
0.0TyrGln: 0.0 ± 0.0
2.717TyrArg: 2.717 ± 0.646
3.458TyrSer: 3.458 ± 0.289
0.988TyrThr: 0.988 ± 0.476
1.235TyrVal: 1.235 ± 0.106
0.0TyrTrp: 0.0 ± 0.0
0.247TyrTyr: 0.247 ± 0.119
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (4049 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski