Amino acid dipepetide frequency for Small anellovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.031AlaAla: 6.031 ± 1.345
1.206AlaCys: 1.206 ± 0.585
3.619AlaAsp: 3.619 ± 6.517
3.619AlaGlu: 3.619 ± 3.876
1.206AlaPhe: 1.206 ± 0.585
0.0AlaGly: 0.0 ± 0.0
1.206AlaHis: 1.206 ± 2.172
4.825AlaIle: 4.825 ± 2.34
3.619AlaLys: 3.619 ± 1.377
2.413AlaLeu: 2.413 ± 2.235
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.206AlaPro: 1.206 ± 0.585
0.0AlaGln: 0.0 ± 0.0
2.413AlaArg: 2.413 ± 1.17
1.206AlaSer: 1.206 ± 2.172
7.238AlaThr: 7.238 ± 1.417
1.206AlaVal: 1.206 ± 2.172
1.206AlaTrp: 1.206 ± 0.585
1.206AlaTyr: 1.206 ± 0.585
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.206CysCys: 1.206 ± 0.585
2.413CysAsp: 2.413 ± 4.345
2.413CysGlu: 2.413 ± 1.722
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.206CysIle: 1.206 ± 0.585
1.206CysLys: 1.206 ± 0.585
2.413CysLeu: 2.413 ± 1.722
0.0CysMet: 0.0 ± 0.0
2.413CysAsn: 2.413 ± 2.235
1.206CysPro: 1.206 ± 2.603
0.0CysGln: 0.0 ± 0.0
2.413CysArg: 2.413 ± 1.722
3.619CysSer: 3.619 ± 1.975
0.0CysThr: 0.0 ± 0.0
1.206CysVal: 1.206 ± 0.585
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.413AspAla: 2.413 ± 4.345
1.206AspCys: 1.206 ± 2.172
1.206AspAsp: 1.206 ± 0.585
0.0AspGlu: 0.0 ± 0.0
6.031AspPhe: 6.031 ± 8.214
2.413AspGly: 2.413 ± 2.235
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
1.206AspLys: 1.206 ± 0.585
3.619AspLeu: 3.619 ± 1.377
0.0AspMet: 0.0 ± 0.0
2.413AspAsn: 2.413 ± 1.17
2.413AspPro: 2.413 ± 1.17
3.619AspGln: 3.619 ± 1.755
1.206AspArg: 1.206 ± 2.172
10.856AspSer: 10.856 ± 1.976
3.619AspThr: 3.619 ± 1.377
1.206AspVal: 1.206 ± 0.585
1.206AspTrp: 1.206 ± 0.585
4.825AspTyr: 4.825 ± 1.869
0.0AspXaa: 0.0 ± 0.0
Glu
2.413GluAla: 2.413 ± 1.17
1.206GluCys: 1.206 ± 2.603
4.825GluAsp: 4.825 ± 6.044
4.825GluGlu: 4.825 ± 6.044
0.0GluPhe: 0.0 ± 0.0
4.825GluGly: 4.825 ± 1.229
0.0GluHis: 0.0 ± 0.0
2.413GluIle: 2.413 ± 1.722
2.413GluLys: 2.413 ± 4.345
1.206GluLeu: 1.206 ± 0.585
1.206GluMet: 1.206 ± 0.585
1.206GluAsn: 1.206 ± 0.585
1.206GluPro: 1.206 ± 0.585
2.413GluGln: 2.413 ± 1.722
1.206GluArg: 1.206 ± 0.585
2.413GluSer: 2.413 ± 1.17
4.825GluThr: 4.825 ± 3.444
1.206GluVal: 1.206 ± 0.585
2.413GluTrp: 2.413 ± 1.17
3.619GluTyr: 3.619 ± 1.755
0.0GluXaa: 0.0 ± 0.0
Phe
2.413PheAla: 2.413 ± 1.722
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
1.206PheGlu: 1.206 ± 0.585
1.206PhePhe: 1.206 ± 0.585
1.206PheGly: 1.206 ± 0.585
2.413PheHis: 2.413 ± 1.17
2.413PheIle: 2.413 ± 1.17
2.413PheLys: 2.413 ± 1.17
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
4.825PhePro: 4.825 ± 1.229
3.619PheGln: 3.619 ± 1.377
1.206PheArg: 1.206 ± 2.172
1.206PheSer: 1.206 ± 0.585
1.206PheThr: 1.206 ± 2.172
3.619PheVal: 3.619 ± 1.755
4.825PheTrp: 4.825 ± 2.34
4.825PheTyr: 4.825 ± 1.229
0.0PheXaa: 0.0 ± 0.0
Gly
3.619GlyAla: 3.619 ± 1.377
2.413GlyCys: 2.413 ± 1.17
1.206GlyAsp: 1.206 ± 2.603
2.413GlyGlu: 2.413 ± 1.17
2.413GlyPhe: 2.413 ± 1.17
10.856GlyGly: 10.856 ± 0.806
2.413GlyHis: 2.413 ± 1.722
1.206GlyIle: 1.206 ± 2.172
4.825GlyLys: 4.825 ± 2.34
1.206GlyLeu: 1.206 ± 0.585
1.206GlyMet: 1.206 ± 2.172
3.619GlyAsn: 3.619 ± 1.755
2.413GlyPro: 2.413 ± 1.17
1.206GlyGln: 1.206 ± 0.585
4.825GlyArg: 4.825 ± 1.229
0.0GlySer: 0.0 ± 0.0
2.413GlyThr: 2.413 ± 2.235
2.413GlyVal: 2.413 ± 2.235
0.0GlyTrp: 0.0 ± 0.0
3.619GlyTyr: 3.619 ± 1.755
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.413HisAsp: 2.413 ± 1.722
1.206HisGlu: 1.206 ± 0.585
1.206HisPhe: 1.206 ± 0.585
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.206HisIle: 1.206 ± 0.585
2.413HisLys: 2.413 ± 2.235
2.413HisLeu: 2.413 ± 3.662
1.206HisMet: 1.206 ± 0.585
0.0HisAsn: 0.0 ± 0.0
3.619HisPro: 3.619 ± 1.975
2.413HisGln: 2.413 ± 2.235
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.206HisThr: 1.206 ± 2.172
0.0HisVal: 0.0 ± 0.0
1.206HisTrp: 1.206 ± 0.585
2.413HisTyr: 2.413 ± 2.235
0.0HisXaa: 0.0 ± 0.0
Ile
3.619IleAla: 3.619 ± 1.377
1.206IleCys: 1.206 ± 0.585
4.825IleAsp: 4.825 ± 2.34
4.825IleGlu: 4.825 ± 3.444
2.413IlePhe: 2.413 ± 1.722
2.413IleGly: 2.413 ± 1.17
1.206IleHis: 1.206 ± 2.603
3.619IleIle: 3.619 ± 1.755
4.825IleLys: 4.825 ± 2.34
3.619IleLeu: 3.619 ± 1.377
1.206IleMet: 1.206 ± 0.585
2.413IleAsn: 2.413 ± 1.17
0.0IlePro: 0.0 ± 0.0
6.031IleGln: 6.031 ± 4.933
0.0IleArg: 0.0 ± 0.0
2.413IleSer: 2.413 ± 1.17
4.825IleThr: 4.825 ± 2.34
6.031IleVal: 6.031 ± 2.926
2.413IleTrp: 2.413 ± 1.17
1.206IleTyr: 1.206 ± 0.585
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
1.206LysCys: 1.206 ± 0.585
3.619LysAsp: 3.619 ± 3.087
6.031LysGlu: 6.031 ± 4.268
1.206LysPhe: 1.206 ± 0.585
2.413LysGly: 2.413 ± 1.17
2.413LysHis: 2.413 ± 2.235
3.619LysIle: 3.619 ± 1.755
13.269LysLys: 13.269 ± 4.079
7.238LysLeu: 7.238 ± 2.174
0.0LysMet: 0.0 ± 0.0
4.825LysAsn: 4.825 ± 1.229
4.825LysPro: 4.825 ± 1.229
3.619LysGln: 3.619 ± 1.755
9.65LysArg: 9.65 ± 0.646
1.206LysSer: 1.206 ± 0.585
10.856LysThr: 10.856 ± 3.151
2.413LysVal: 2.413 ± 1.17
3.619LysTrp: 3.619 ± 1.755
7.238LysTyr: 7.238 ± 3.511
0.0LysXaa: 0.0 ± 0.0
Leu
4.825LeuAla: 4.825 ± 3.444
2.413LeuCys: 2.413 ± 1.17
1.206LeuAsp: 1.206 ± 0.585
2.413LeuGlu: 2.413 ± 1.17
0.0LeuPhe: 0.0 ± 0.0
2.413LeuGly: 2.413 ± 1.17
2.413LeuHis: 2.413 ± 2.235
4.825LeuIle: 4.825 ± 4.471
7.238LeuLys: 7.238 ± 2.174
9.65LeuLeu: 9.65 ± 7.92
0.0LeuMet: 0.0 ± 0.0
2.413LeuAsn: 2.413 ± 1.17
8.444LeuPro: 8.444 ± 2.524
4.825LeuGln: 4.825 ± 2.34
3.619LeuArg: 3.619 ± 1.755
6.031LeuSer: 6.031 ± 4.268
3.619LeuThr: 3.619 ± 3.087
1.206LeuVal: 1.206 ± 0.585
2.413LeuTrp: 2.413 ± 1.17
3.619LeuTyr: 3.619 ± 1.755
0.0LeuXaa: 0.0 ± 0.0
Met
1.206MetAla: 1.206 ± 2.172
1.206MetCys: 1.206 ± 2.603
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
2.413MetPhe: 2.413 ± 1.17
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.206MetIle: 1.206 ± 0.585
1.206MetLys: 1.206 ± 0.585
2.413MetLeu: 2.413 ± 1.17
1.206MetMet: 1.206 ± 2.603
1.206MetAsn: 1.206 ± 0.585
1.206MetPro: 1.206 ± 0.585
2.413MetGln: 2.413 ± 1.722
0.0MetArg: 0.0 ± 0.0
1.206MetSer: 1.206 ± 2.172
2.413MetThr: 2.413 ± 2.235
1.206MetVal: 1.206 ± 0.585
1.206MetTrp: 1.206 ± 2.172
1.206MetTyr: 1.206 ± 0.585
0.0MetXaa: 0.0 ± 0.0
Asn
1.206AsnAla: 1.206 ± 0.585
1.206AsnCys: 1.206 ± 2.172
0.0AsnAsp: 0.0 ± 0.0
1.206AsnGlu: 1.206 ± 0.585
1.206AsnPhe: 1.206 ± 0.585
1.206AsnGly: 1.206 ± 0.585
0.0AsnHis: 0.0 ± 0.0
4.825AsnIle: 4.825 ± 1.229
7.238AsnLys: 7.238 ± 2.174
4.825AsnLeu: 4.825 ± 2.518
0.0AsnMet: 0.0 ± 0.0
2.413AsnAsn: 2.413 ± 1.17
4.825AsnPro: 4.825 ± 2.34
4.825AsnGln: 4.825 ± 2.518
1.206AsnArg: 1.206 ± 0.585
3.619AsnSer: 3.619 ± 1.377
1.206AsnThr: 1.206 ± 0.585
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
6.031AsnTyr: 6.031 ± 2.926
0.0AsnXaa: 0.0 ± 0.0
Pro
4.825ProAla: 4.825 ± 2.34
1.206ProCys: 1.206 ± 2.172
3.619ProAsp: 3.619 ± 1.755
0.0ProGlu: 0.0 ± 0.0
3.619ProPhe: 3.619 ± 1.377
3.619ProGly: 3.619 ± 1.377
0.0ProHis: 0.0 ± 0.0
2.413ProIle: 2.413 ± 2.235
4.825ProLys: 4.825 ± 2.34
3.619ProLeu: 3.619 ± 1.755
0.0ProMet: 0.0 ± 0.0
2.413ProAsn: 2.413 ± 1.17
3.619ProPro: 3.619 ± 1.377
4.825ProGln: 4.825 ± 1.869
6.031ProArg: 6.031 ± 1.941
1.206ProSer: 1.206 ± 0.585
2.413ProThr: 2.413 ± 1.17
2.413ProVal: 2.413 ± 1.17
1.206ProTrp: 1.206 ± 0.585
3.619ProTyr: 3.619 ± 1.755
0.0ProXaa: 0.0 ± 0.0
Gln
1.206GlnAla: 1.206 ± 0.585
2.413GlnCys: 2.413 ± 2.235
1.206GlnAsp: 1.206 ± 0.585
1.206GlnGlu: 1.206 ± 2.172
2.413GlnPhe: 2.413 ± 1.17
1.206GlnGly: 1.206 ± 0.585
3.619GlnHis: 3.619 ± 1.975
2.413GlnIle: 2.413 ± 1.17
7.238GlnLys: 7.238 ± 1.417
6.031GlnLeu: 6.031 ± 4.178
2.413GlnMet: 2.413 ± 1.722
4.825GlnAsn: 4.825 ± 4.848
3.619GlnPro: 3.619 ± 1.755
7.238GlnGln: 7.238 ± 3.951
1.206GlnArg: 1.206 ± 0.585
4.825GlnSer: 4.825 ± 4.471
9.65GlnThr: 9.65 ± 2.949
0.0GlnVal: 0.0 ± 0.0
3.619GlnTrp: 3.619 ± 1.755
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
2.413ArgAsp: 2.413 ± 1.722
1.206ArgGlu: 1.206 ± 2.172
3.619ArgPhe: 3.619 ± 1.755
3.619ArgGly: 3.619 ± 1.975
1.206ArgHis: 1.206 ± 0.585
2.413ArgIle: 2.413 ± 1.17
8.444ArgLys: 8.444 ± 0.933
2.413ArgLeu: 2.413 ± 1.17
3.619ArgMet: 3.619 ± 1.237
3.619ArgAsn: 3.619 ± 1.755
1.206ArgPro: 1.206 ± 0.585
3.619ArgGln: 3.619 ± 1.755
19.3ArgArg: 19.3 ± 9.362
1.206ArgSer: 1.206 ± 0.585
4.825ArgThr: 4.825 ± 3.444
0.0ArgVal: 0.0 ± 0.0
1.206ArgTrp: 1.206 ± 0.585
6.031ArgTyr: 6.031 ± 1.345
0.0ArgXaa: 0.0 ± 0.0
Ser
2.413SerAla: 2.413 ± 3.662
0.0SerCys: 0.0 ± 0.0
3.619SerAsp: 3.619 ± 1.755
2.413SerGlu: 2.413 ± 1.17
2.413SerPhe: 2.413 ± 1.17
6.031SerGly: 6.031 ± 5.591
1.206SerHis: 1.206 ± 2.172
4.825SerIle: 4.825 ± 1.229
4.825SerLys: 4.825 ± 1.869
4.825SerLeu: 4.825 ± 2.34
3.619SerMet: 3.619 ± 4.093
2.413SerAsn: 2.413 ± 2.235
1.206SerPro: 1.206 ± 0.585
2.413SerGln: 2.413 ± 2.235
0.0SerArg: 0.0 ± 0.0
2.413SerSer: 2.413 ± 2.235
3.619SerThr: 3.619 ± 1.755
2.413SerVal: 2.413 ± 1.17
1.206SerTrp: 1.206 ± 2.172
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
1.206ThrAla: 1.206 ± 0.585
1.206ThrCys: 1.206 ± 2.172
4.825ThrAsp: 4.825 ± 2.518
6.031ThrGlu: 6.031 ± 1.345
1.206ThrPhe: 1.206 ± 0.585
1.206ThrGly: 1.206 ± 2.603
3.619ThrHis: 3.619 ± 1.975
8.444ThrIle: 8.444 ± 2.543
7.238ThrLys: 7.238 ± 1.671
3.619ThrLeu: 3.619 ± 1.975
1.206ThrMet: 1.206 ± 0.585
3.619ThrAsn: 3.619 ± 1.377
3.619ThrPro: 3.619 ± 1.377
4.825ThrGln: 4.825 ± 4.471
6.031ThrArg: 6.031 ± 3.062
2.413ThrSer: 2.413 ± 2.235
2.413ThrThr: 2.413 ± 2.235
1.206ThrVal: 1.206 ± 0.585
1.206ThrTrp: 1.206 ± 0.585
3.619ThrTyr: 3.619 ± 1.755
0.0ThrXaa: 0.0 ± 0.0
Val
3.619ValAla: 3.619 ± 3.087
0.0ValCys: 0.0 ± 0.0
1.206ValAsp: 1.206 ± 0.585
1.206ValGlu: 1.206 ± 0.585
1.206ValPhe: 1.206 ± 0.585
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
2.413ValIle: 2.413 ± 1.17
0.0ValLys: 0.0 ± 0.0
4.825ValLeu: 4.825 ± 2.34
1.206ValMet: 1.206 ± 0.585
2.413ValAsn: 2.413 ± 1.17
3.619ValPro: 3.619 ± 1.755
2.413ValGln: 2.413 ± 1.17
2.413ValArg: 2.413 ± 1.17
1.206ValSer: 1.206 ± 0.585
0.0ValThr: 0.0 ± 0.0
1.206ValVal: 1.206 ± 0.585
0.0ValTrp: 0.0 ± 0.0
1.206ValTyr: 1.206 ± 0.585
0.0ValXaa: 0.0 ± 0.0
Trp
1.206TrpAla: 1.206 ± 0.585
1.206TrpCys: 1.206 ± 2.172
2.413TrpAsp: 2.413 ± 1.17
1.206TrpGlu: 1.206 ± 0.585
2.413TrpPhe: 2.413 ± 1.17
8.444TrpGly: 8.444 ± 4.096
0.0TrpHis: 0.0 ± 0.0
1.206TrpIle: 1.206 ± 0.585
1.206TrpLys: 1.206 ± 0.585
2.413TrpLeu: 2.413 ± 1.17
1.206TrpMet: 1.206 ± 2.172
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.413TrpGln: 2.413 ± 1.17
1.206TrpArg: 1.206 ± 0.585
0.0TrpSer: 0.0 ± 0.0
1.206TrpThr: 1.206 ± 0.585
0.0TrpVal: 0.0 ± 0.0
1.206TrpTrp: 1.206 ± 0.585
1.206TrpTyr: 1.206 ± 0.585
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.206TyrAla: 1.206 ± 0.585
1.206TyrCys: 1.206 ± 0.585
4.825TyrAsp: 4.825 ± 2.34
2.413TyrGlu: 2.413 ± 1.17
2.413TyrPhe: 2.413 ± 1.17
2.413TyrGly: 2.413 ± 1.17
1.206TyrHis: 1.206 ± 0.585
3.619TyrIle: 3.619 ± 1.755
3.619TyrLys: 3.619 ± 3.087
4.825TyrLeu: 4.825 ± 2.34
2.413TyrMet: 2.413 ± 1.17
4.825TyrAsn: 4.825 ± 1.229
2.413TyrPro: 2.413 ± 1.17
3.619TyrGln: 3.619 ± 1.975
7.238TyrArg: 7.238 ± 3.511
4.825TyrSer: 4.825 ± 2.34
1.206TyrThr: 1.206 ± 0.585
1.206TyrVal: 1.206 ± 0.585
0.0TyrTrp: 0.0 ± 0.0
3.619TyrTyr: 3.619 ± 1.975
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (830 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski