Amino acid dipepetide frequency for Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198) (Campylobacter mustelae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.922AlaAla: 3.922 ± 0.154
0.994AlaCys: 0.994 ± 0.067
2.646AlaAsp: 2.646 ± 0.096
3.116AlaGlu: 3.116 ± 0.091
3.426AlaPhe: 3.426 ± 0.094
4.487AlaGly: 4.487 ± 0.15
1.531AlaHis: 1.531 ± 0.061
6.074AlaIle: 6.074 ± 0.115
6.421AlaLys: 6.421 ± 0.135
9.034AlaLeu: 9.034 ± 0.178
1.958AlaMet: 1.958 ± 0.066
3.823AlaAsn: 3.823 ± 0.191
2.486AlaPro: 2.486 ± 0.09
3.631AlaGln: 3.631 ± 0.1
3.519AlaArg: 3.519 ± 0.101
4.944AlaSer: 4.944 ± 0.145
3.353AlaThr: 3.353 ± 0.155
3.254AlaVal: 3.254 ± 0.099
0.533AlaTrp: 0.533 ± 0.032
2.615AlaTyr: 2.615 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
1.082CysAla: 1.082 ± 0.056
0.147CysCys: 0.147 ± 0.021
0.671CysAsp: 0.671 ± 0.044
0.757CysGlu: 0.757 ± 0.041
0.679CysPhe: 0.679 ± 0.04
1.02CysGly: 1.02 ± 0.051
0.27CysHis: 0.27 ± 0.028
0.994CysIle: 0.994 ± 0.046
0.88CysLys: 0.88 ± 0.042
0.996CysLeu: 0.996 ± 0.051
0.276CysMet: 0.276 ± 0.025
0.474CysAsn: 0.474 ± 0.039
0.416CysPro: 0.416 ± 0.037
0.414CysGln: 0.414 ± 0.032
0.371CysArg: 0.371 ± 0.03
0.634CysSer: 0.634 ± 0.037
0.466CysThr: 0.466 ± 0.032
0.845CysVal: 0.845 ± 0.048
0.069CysTrp: 0.069 ± 0.012
0.42CysTyr: 0.42 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
4.051AspAla: 4.051 ± 0.104
0.671AspCys: 0.671 ± 0.035
1.803AspAsp: 1.803 ± 0.061
2.859AspGlu: 2.859 ± 0.094
4.06AspPhe: 4.06 ± 0.104
3.37AspGly: 3.37 ± 0.098
0.869AspHis: 0.869 ± 0.043
3.944AspIle: 3.944 ± 0.106
3.258AspLys: 3.258 ± 0.095
5.252AspLeu: 5.252 ± 0.12
1.089AspMet: 1.089 ± 0.054
1.624AspAsn: 1.624 ± 0.061
1.826AspPro: 1.826 ± 0.085
1.188AspGln: 1.188 ± 0.053
2.001AspArg: 2.001 ± 0.068
3.303AspSer: 3.303 ± 0.083
2.143AspThr: 2.143 ± 0.071
3.047AspVal: 3.047 ± 0.086
0.364AspTrp: 0.364 ± 0.029
2.014AspTyr: 2.014 ± 0.064
0.0AspXaa: 0.0 ± 0.0
Glu
4.123GluAla: 4.123 ± 0.112
0.645GluCys: 0.645 ± 0.039
2.939GluAsp: 2.939 ± 0.093
5.138GluGlu: 5.138 ± 0.173
3.073GluPhe: 3.073 ± 0.093
3.903GluGly: 3.903 ± 0.102
1.302GluHis: 1.302 ± 0.05
6.376GluIle: 6.376 ± 0.162
5.591GluLys: 5.591 ± 0.149
5.884GluLeu: 5.884 ± 0.139
1.718GluMet: 1.718 ± 0.057
3.756GluAsn: 3.756 ± 0.093
1.367GluPro: 1.367 ± 0.062
2.566GluGln: 2.566 ± 0.09
2.844GluArg: 2.844 ± 0.107
3.555GluSer: 3.555 ± 0.099
1.852GluThr: 1.852 ± 0.058
4.082GluVal: 4.082 ± 0.118
0.487GluTrp: 0.487 ± 0.028
1.999GluTyr: 1.999 ± 0.065
0.0GluXaa: 0.0 ± 0.0
Phe
4.131PheAla: 4.131 ± 0.101
1.089PheCys: 1.089 ± 0.057
3.15PheAsp: 3.15 ± 0.082
3.176PheGlu: 3.176 ± 0.109
3.801PhePhe: 3.801 ± 0.125
4.459PheGly: 4.459 ± 0.119
1.089PheHis: 1.089 ± 0.051
3.476PheIle: 3.476 ± 0.112
2.559PheLys: 2.559 ± 0.077
6.727PheLeu: 6.727 ± 0.185
1.231PheMet: 1.231 ± 0.064
1.863PheAsn: 1.863 ± 0.078
1.537PhePro: 1.537 ± 0.059
1.531PheGln: 1.531 ± 0.062
1.628PheArg: 1.628 ± 0.064
4.338PheSer: 4.338 ± 0.117
2.152PheThr: 2.152 ± 0.081
3.534PheVal: 3.534 ± 0.096
0.53PheTrp: 0.53 ± 0.037
2.296PheTyr: 2.296 ± 0.092
0.0PheXaa: 0.0 ± 0.0
Gly
5.121GlyAla: 5.121 ± 0.19
0.714GlyCys: 0.714 ± 0.054
3.247GlyAsp: 3.247 ± 0.082
4.013GlyGlu: 4.013 ± 0.109
3.987GlyPhe: 3.987 ± 0.107
5.891GlyGly: 5.891 ± 0.26
1.22GlyHis: 1.22 ± 0.062
6.382GlyIle: 6.382 ± 0.128
4.756GlyLys: 4.756 ± 0.12
5.783GlyLeu: 5.783 ± 0.13
2.027GlyMet: 2.027 ± 0.072
3.439GlyAsn: 3.439 ± 0.251
1.186GlyPro: 1.186 ± 0.065
2.014GlyGln: 2.014 ± 0.101
2.745GlyArg: 2.745 ± 0.091
4.662GlySer: 4.662 ± 0.2
2.717GlyThr: 2.717 ± 0.133
5.375GlyVal: 5.375 ± 0.117
0.5GlyTrp: 0.5 ± 0.037
2.855GlyTyr: 2.855 ± 0.078
0.0GlyXaa: 0.0 ± 0.0
His
1.749HisAla: 1.749 ± 0.071
0.358HisCys: 0.358 ± 0.03
0.811HisAsp: 0.811 ± 0.05
0.873HisGlu: 0.873 ± 0.046
1.524HisPhe: 1.524 ± 0.061
1.341HisGly: 1.341 ± 0.064
0.709HisHis: 0.709 ± 0.043
1.684HisIle: 1.684 ± 0.066
1.578HisLys: 1.578 ± 0.07
2.411HisLeu: 2.411 ± 0.08
0.349HisMet: 0.349 ± 0.028
0.919HisAsn: 0.919 ± 0.047
1.134HisPro: 1.134 ± 0.06
1.287HisGln: 1.287 ± 0.06
0.884HisArg: 0.884 ± 0.041
1.386HisSer: 1.386 ± 0.055
1.063HisThr: 1.063 ± 0.059
0.903HisVal: 0.903 ± 0.042
0.157HisTrp: 0.157 ± 0.018
0.951HisTyr: 0.951 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
7.072IleAla: 7.072 ± 0.151
1.11IleCys: 1.11 ± 0.06
4.036IleAsp: 4.036 ± 0.096
4.94IleGlu: 4.94 ± 0.147
4.703IlePhe: 4.703 ± 0.115
5.483IleGly: 5.483 ± 0.128
1.893IleHis: 1.893 ± 0.07
5.645IleIle: 5.645 ± 0.14
6.111IleLys: 6.111 ± 0.142
9.478IleLeu: 9.478 ± 0.182
1.378IleMet: 1.378 ± 0.064
3.241IleAsn: 3.241 ± 0.096
3.415IlePro: 3.415 ± 0.096
3.079IleGln: 3.079 ± 0.102
2.557IleArg: 2.557 ± 0.082
5.214IleSer: 5.214 ± 0.112
4.879IleThr: 4.879 ± 0.182
3.952IleVal: 3.952 ± 0.112
0.548IleTrp: 0.548 ± 0.035
2.799IleTyr: 2.799 ± 0.081
0.0IleXaa: 0.0 ± 0.0
Lys
4.446LysAla: 4.446 ± 0.108
0.483LysCys: 0.483 ± 0.036
4.59LysAsp: 4.59 ± 0.132
7.044LysGlu: 7.044 ± 0.19
2.626LysPhe: 2.626 ± 0.077
3.838LysGly: 3.838 ± 0.094
1.438LysHis: 1.438 ± 0.049
7.844LysIle: 7.844 ± 0.137
7.406LysLys: 7.406 ± 0.165
5.479LysLeu: 5.479 ± 0.119
2.1LysMet: 2.1 ± 0.066
6.098LysAsn: 6.098 ± 0.131
2.219LysPro: 2.219 ± 0.075
3.077LysGln: 3.077 ± 0.086
2.891LysArg: 2.891 ± 0.093
4.756LysSer: 4.756 ± 0.103
3.741LysThr: 3.741 ± 0.109
3.465LysVal: 3.465 ± 0.092
0.455LysTrp: 0.455 ± 0.034
2.15LysTyr: 2.15 ± 0.065
0.0LysXaa: 0.0 ± 0.0
Leu
7.635LeuAla: 7.635 ± 0.138
1.628LeuCys: 1.628 ± 0.068
5.673LeuAsp: 5.673 ± 0.113
7.932LeuGlu: 7.932 ± 0.173
5.205LeuPhe: 5.205 ± 0.157
7.465LeuGly: 7.465 ± 0.148
2.505LeuHis: 2.505 ± 0.096
6.788LeuIle: 6.788 ± 0.151
7.73LeuLys: 7.73 ± 0.158
10.776LeuLeu: 10.776 ± 0.302
2.115LeuMet: 2.115 ± 0.072
4.278LeuAsn: 4.278 ± 0.116
3.969LeuPro: 3.969 ± 0.112
5.44LeuGln: 5.44 ± 0.145
4.474LeuArg: 4.474 ± 0.104
7.445LeuSer: 7.445 ± 0.139
3.786LeuThr: 3.786 ± 0.096
5.015LeuVal: 5.015 ± 0.126
0.815LeuTrp: 0.815 ± 0.048
3.292LeuTyr: 3.292 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
1.561MetAla: 1.561 ± 0.069
0.188MetCys: 0.188 ± 0.02
1.205MetAsp: 1.205 ± 0.055
1.391MetGlu: 1.391 ± 0.058
0.875MetPhe: 0.875 ± 0.047
1.8MetGly: 1.8 ± 0.068
0.548MetHis: 0.548 ± 0.035
1.925MetIle: 1.925 ± 0.069
1.684MetLys: 1.684 ± 0.059
2.738MetLeu: 2.738 ± 0.084
0.561MetMet: 0.561 ± 0.035
0.865MetAsn: 0.865 ± 0.044
1.022MetPro: 1.022 ± 0.045
1.677MetGln: 1.677 ± 0.066
1.223MetArg: 1.223 ± 0.046
1.386MetSer: 1.386 ± 0.054
0.817MetThr: 0.817 ± 0.043
1.266MetVal: 1.266 ± 0.056
0.162MetTrp: 0.162 ± 0.021
0.479MetTyr: 0.479 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
4.243AsnAla: 4.243 ± 0.195
0.414AsnCys: 0.414 ± 0.03
1.837AsnAsp: 1.837 ± 0.073
2.279AsnGlu: 2.279 ± 0.081
2.891AsnPhe: 2.891 ± 0.091
3.258AsnGly: 3.258 ± 0.199
1.225AsnHis: 1.225 ± 0.065
4.323AsnIle: 4.323 ± 0.154
3.014AsnLys: 3.014 ± 0.084
5.647AsnLeu: 5.647 ± 0.128
0.897AsnMet: 0.897 ± 0.045
2.363AsnAsn: 2.363 ± 0.186
2.9AsnPro: 2.9 ± 0.09
2.083AsnGln: 2.083 ± 0.088
1.604AsnArg: 1.604 ± 0.066
2.943AsnSer: 2.943 ± 0.117
2.857AsnThr: 2.857 ± 0.207
2.607AsnVal: 2.607 ± 0.098
0.229AsnTrp: 0.229 ± 0.023
1.775AsnTyr: 1.775 ± 0.072
0.0AsnXaa: 0.0 ± 0.0
Pro
2.21ProAla: 2.21 ± 0.083
0.397ProCys: 0.397 ± 0.034
1.419ProAsp: 1.419 ± 0.06
1.798ProGlu: 1.798 ± 0.071
1.787ProPhe: 1.787 ± 0.076
1.626ProGly: 1.626 ± 0.078
1.097ProHis: 1.097 ± 0.058
2.945ProIle: 2.945 ± 0.1
3.068ProLys: 3.068 ± 0.102
3.86ProLeu: 3.86 ± 0.099
0.832ProMet: 0.832 ± 0.043
1.796ProAsn: 1.796 ± 0.069
1.281ProPro: 1.281 ± 0.074
1.686ProGln: 1.686 ± 0.079
1.345ProArg: 1.345 ± 0.056
2.665ProSer: 2.665 ± 0.09
2.035ProThr: 2.035 ± 0.068
1.621ProVal: 1.621 ± 0.057
0.276ProTrp: 0.276 ± 0.024
1.481ProTyr: 1.481 ± 0.061
0.0ProXaa: 0.0 ± 0.0
Gln
2.756GlnAla: 2.756 ± 0.099
0.313GlnCys: 0.313 ± 0.025
2.436GlnAsp: 2.436 ± 0.077
3.866GlnGlu: 3.866 ± 0.118
1.195GlnPhe: 1.195 ± 0.05
2.643GlnGly: 2.643 ± 0.138
0.651GlnHis: 0.651 ± 0.042
3.504GlnIle: 3.504 ± 0.087
5.16GlnLys: 5.16 ± 0.13
2.309GlnLeu: 2.309 ± 0.068
1.044GlnMet: 1.044 ± 0.048
3.661GlnAsn: 3.661 ± 0.13
0.908GlnPro: 0.908 ± 0.061
1.3GlnGln: 1.3 ± 0.058
1.852GlnArg: 1.852 ± 0.075
2.939GlnSer: 2.939 ± 0.084
2.042GlnThr: 2.042 ± 0.08
1.887GlnVal: 1.887 ± 0.072
0.241GlnTrp: 0.241 ± 0.023
1.121GlnTyr: 1.121 ± 0.048
0.0GlnXaa: 0.0 ± 0.0
Arg
2.967ArgAla: 2.967 ± 0.087
0.367ArgCys: 0.367 ± 0.029
2.529ArgAsp: 2.529 ± 0.077
3.355ArgGlu: 3.355 ± 0.107
2.186ArgPhe: 2.186 ± 0.064
2.82ArgGly: 2.82 ± 0.082
0.787ArgHis: 0.787 ± 0.041
3.672ArgIle: 3.672 ± 0.099
2.544ArgLys: 2.544 ± 0.081
3.773ArgLeu: 3.773 ± 0.097
0.97ArgMet: 0.97 ± 0.047
1.9ArgAsn: 1.9 ± 0.064
1.044ArgPro: 1.044 ± 0.045
1.352ArgGln: 1.352 ± 0.063
1.572ArgArg: 1.572 ± 0.058
2.113ArgSer: 2.113 ± 0.069
1.395ArgThr: 1.395 ± 0.055
2.542ArgVal: 2.542 ± 0.087
0.263ArgTrp: 0.263 ± 0.023
1.688ArgTyr: 1.688 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.778SerAla: 4.778 ± 0.122
0.651SerCys: 0.651 ± 0.038
2.786SerAsp: 2.786 ± 0.08
2.762SerGlu: 2.762 ± 0.099
3.881SerPhe: 3.881 ± 0.107
4.91SerGly: 4.91 ± 0.165
1.613SerHis: 1.613 ± 0.059
5.513SerIle: 5.513 ± 0.127
4.823SerLys: 4.823 ± 0.113
7.678SerLeu: 7.678 ± 0.17
1.701SerMet: 1.701 ± 0.077
2.971SerAsn: 2.971 ± 0.159
2.398SerPro: 2.398 ± 0.092
2.797SerGln: 2.797 ± 0.084
2.398SerArg: 2.398 ± 0.078
4.543SerSer: 4.543 ± 0.13
3.258SerThr: 3.258 ± 0.163
3.594SerVal: 3.594 ± 0.093
0.464SerTrp: 0.464 ± 0.032
2.374SerTyr: 2.374 ± 0.071
0.0SerXaa: 0.0 ± 0.0
Thr
2.693ThrAla: 2.693 ± 0.105
0.414ThrCys: 0.414 ± 0.034
1.712ThrAsp: 1.712 ± 0.069
1.913ThrGlu: 1.913 ± 0.064
2.255ThrPhe: 2.255 ± 0.084
2.894ThrGly: 2.894 ± 0.164
1.164ThrHis: 1.164 ± 0.043
3.206ThrIle: 3.206 ± 0.148
3.637ThrLys: 3.637 ± 0.1
5.591ThrLeu: 5.591 ± 0.16
0.875ThrMet: 0.875 ± 0.048
2.148ThrAsn: 2.148 ± 0.125
2.82ThrPro: 2.82 ± 0.104
2.555ThrGln: 2.555 ± 0.082
1.753ThrArg: 1.753 ± 0.063
3.129ThrSer: 3.129 ± 0.11
2.775ThrThr: 2.775 ± 0.142
1.529ThrVal: 1.529 ± 0.08
0.317ThrTrp: 0.317 ± 0.026
1.544ThrTyr: 1.544 ± 0.064
0.0ThrXaa: 0.0 ± 0.0
Val
3.937ValAla: 3.937 ± 0.113
0.802ValCys: 0.802 ± 0.036
2.967ValAsp: 2.967 ± 0.087
3.122ValGlu: 3.122 ± 0.097
3.545ValPhe: 3.545 ± 0.105
4.245ValGly: 4.245 ± 0.122
1.044ValHis: 1.044 ± 0.058
4.455ValIle: 4.455 ± 0.108
3.051ValLys: 3.051 ± 0.094
6.257ValLeu: 6.257 ± 0.13
1.389ValMet: 1.389 ± 0.064
2.227ValAsn: 2.227 ± 0.089
1.753ValPro: 1.753 ± 0.079
1.962ValGln: 1.962 ± 0.064
2.305ValArg: 2.305 ± 0.081
3.618ValSer: 3.618 ± 0.093
1.887ValThr: 1.887 ± 0.089
3.773ValVal: 3.773 ± 0.112
0.489ValTrp: 0.489 ± 0.032
1.813ValTyr: 1.813 ± 0.069
0.0ValXaa: 0.0 ± 0.0
Trp
0.489TrpAla: 0.489 ± 0.032
0.101TrpCys: 0.101 ± 0.015
0.401TrpAsp: 0.401 ± 0.029
0.481TrpGlu: 0.481 ± 0.033
0.321TrpPhe: 0.321 ± 0.027
0.546TrpGly: 0.546 ± 0.04
0.188TrpHis: 0.188 ± 0.018
0.647TrpIle: 0.647 ± 0.032
0.444TrpLys: 0.444 ± 0.033
0.839TrpLeu: 0.839 ± 0.047
0.261TrpMet: 0.261 ± 0.024
0.362TrpAsn: 0.362 ± 0.03
0.112TrpPro: 0.112 ± 0.016
0.334TrpGln: 0.334 ± 0.028
0.358TrpArg: 0.358 ± 0.026
0.382TrpSer: 0.382 ± 0.033
0.155TrpThr: 0.155 ± 0.02
0.479TrpVal: 0.479 ± 0.037
0.088TrpTrp: 0.088 ± 0.013
0.265TrpTyr: 0.265 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.799TyrAla: 2.799 ± 0.077
0.397TyrCys: 0.397 ± 0.035
1.878TyrAsp: 1.878 ± 0.065
2.387TyrGlu: 2.387 ± 0.08
2.277TyrPhe: 2.277 ± 0.074
2.635TyrGly: 2.635 ± 0.086
0.929TyrHis: 0.929 ± 0.046
2.137TyrIle: 2.137 ± 0.072
2.43TyrLys: 2.43 ± 0.08
3.454TyrLeu: 3.454 ± 0.092
0.599TyrMet: 0.599 ± 0.035
1.583TyrAsn: 1.583 ± 0.071
1.434TyrPro: 1.434 ± 0.06
1.854TyrGln: 1.854 ± 0.069
1.516TyrArg: 1.516 ± 0.06
1.936TyrSer: 1.936 ± 0.062
1.55TyrThr: 1.55 ± 0.063
1.872TyrVal: 1.872 ± 0.061
0.265TyrTrp: 0.265 ± 0.026
1.475TyrTyr: 1.475 ± 0.068
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1400 proteins (463791 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski