Amino acid dipepetide frequency for Stachybotrys chlorohalonata (strain IBT 40285)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.297AlaAla: 10.297 ± 0.069
1.097AlaCys: 1.097 ± 0.018
4.673AlaAsp: 4.673 ± 0.034
5.367AlaGlu: 5.367 ± 0.043
3.159AlaPhe: 3.159 ± 0.027
6.177AlaGly: 6.177 ± 0.042
1.896AlaHis: 1.896 ± 0.02
4.219AlaIle: 4.219 ± 0.031
3.947AlaLys: 3.947 ± 0.036
8.005AlaLeu: 8.005 ± 0.047
2.142AlaMet: 2.142 ± 0.02
3.047AlaAsn: 3.047 ± 0.027
5.127AlaPro: 5.127 ± 0.047
3.676AlaGln: 3.676 ± 0.032
5.341AlaArg: 5.341 ± 0.038
7.623AlaSer: 7.623 ± 0.051
5.553AlaThr: 5.553 ± 0.04
5.879AlaVal: 5.879 ± 0.039
1.267AlaTrp: 1.267 ± 0.019
2.259AlaTyr: 2.259 ± 0.023
0.002AlaXaa: 0.002 ± 0.0
Cys
0.948CysAla: 0.948 ± 0.015
0.234CysCys: 0.234 ± 0.008
0.661CysAsp: 0.661 ± 0.011
0.58CysGlu: 0.58 ± 0.012
0.537CysPhe: 0.537 ± 0.011
0.954CysGly: 0.954 ± 0.018
0.348CysHis: 0.348 ± 0.008
0.689CysIle: 0.689 ± 0.014
0.471CysLys: 0.471 ± 0.011
1.228CysLeu: 1.228 ± 0.017
0.258CysMet: 0.258 ± 0.007
0.432CysAsn: 0.432 ± 0.009
0.665CysPro: 0.665 ± 0.014
0.456CysGln: 0.456 ± 0.01
0.785CysArg: 0.785 ± 0.012
0.876CysSer: 0.876 ± 0.014
0.69CysThr: 0.69 ± 0.014
0.787CysVal: 0.787 ± 0.012
0.212CysTrp: 0.212 ± 0.007
0.338CysTyr: 0.338 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.285AspAla: 5.285 ± 0.039
0.641AspCys: 0.641 ± 0.013
4.694AspAsp: 4.694 ± 0.044
4.612AspGlu: 4.612 ± 0.039
2.25AspPhe: 2.25 ± 0.023
4.39AspGly: 4.39 ± 0.036
1.304AspHis: 1.304 ± 0.023
2.958AspIle: 2.958 ± 0.029
2.463AspLys: 2.463 ± 0.031
5.137AspLeu: 5.137 ± 0.036
1.375AspMet: 1.375 ± 0.016
1.922AspAsn: 1.922 ± 0.019
3.286AspPro: 3.286 ± 0.026
1.928AspGln: 1.928 ± 0.022
3.168AspArg: 3.168 ± 0.039
4.102AspSer: 4.102 ± 0.036
2.939AspThr: 2.939 ± 0.025
3.94AspVal: 3.94 ± 0.026
0.903AspTrp: 0.903 ± 0.014
1.594AspTyr: 1.594 ± 0.017
0.001AspXaa: 0.001 ± 0.0
Glu
5.765GluAla: 5.765 ± 0.045
0.609GluCys: 0.609 ± 0.012
4.301GluAsp: 4.301 ± 0.037
5.219GluGlu: 5.219 ± 0.054
1.855GluPhe: 1.855 ± 0.02
3.647GluGly: 3.647 ± 0.029
1.427GluHis: 1.427 ± 0.017
2.796GluIle: 2.796 ± 0.026
3.234GluLys: 3.234 ± 0.036
5.299GluLeu: 5.299 ± 0.044
1.428GluMet: 1.428 ± 0.018
2.056GluAsn: 2.056 ± 0.023
3.004GluPro: 3.004 ± 0.036
2.506GluGln: 2.506 ± 0.024
3.808GluArg: 3.808 ± 0.035
4.094GluSer: 4.094 ± 0.031
3.488GluThr: 3.488 ± 0.032
3.59GluVal: 3.59 ± 0.028
0.896GluTrp: 0.896 ± 0.013
1.616GluTyr: 1.616 ± 0.02
0.0GluXaa: 0.0 ± 0.0
Phe
3.09PheAla: 3.09 ± 0.024
0.532PheCys: 0.532 ± 0.011
2.27PheAsp: 2.27 ± 0.019
2.117PheGlu: 2.117 ± 0.021
1.565PhePhe: 1.565 ± 0.021
2.787PheGly: 2.787 ± 0.031
0.913PheHis: 0.913 ± 0.014
1.721PheIle: 1.721 ± 0.018
1.387PheLys: 1.387 ± 0.02
3.337PheLeu: 3.337 ± 0.028
0.789PheMet: 0.789 ± 0.011
1.373PheAsn: 1.373 ± 0.015
1.907PhePro: 1.907 ± 0.02
1.392PheGln: 1.392 ± 0.017
1.999PheArg: 1.999 ± 0.021
2.842PheSer: 2.842 ± 0.027
2.099PheThr: 2.099 ± 0.019
2.4PheVal: 2.4 ± 0.022
0.635PheTrp: 0.635 ± 0.011
1.07PheTyr: 1.07 ± 0.017
0.0PheXaa: 0.0 ± 0.0
Gly
5.58GlyAla: 5.58 ± 0.041
0.863GlyCys: 0.863 ± 0.014
3.811GlyAsp: 3.811 ± 0.031
3.588GlyGlu: 3.588 ± 0.029
2.816GlyPhe: 2.816 ± 0.028
5.807GlyGly: 5.807 ± 0.059
1.789GlyHis: 1.789 ± 0.023
3.434GlyIle: 3.434 ± 0.031
3.189GlyLys: 3.189 ± 0.028
6.213GlyLeu: 6.213 ± 0.041
1.581GlyMet: 1.581 ± 0.019
2.561GlyAsn: 2.561 ± 0.029
3.544GlyPro: 3.544 ± 0.037
2.715GlyGln: 2.715 ± 0.025
4.452GlyArg: 4.452 ± 0.034
5.819GlySer: 5.819 ± 0.038
4.028GlyThr: 4.028 ± 0.046
4.398GlyVal: 4.398 ± 0.032
1.189GlyTrp: 1.189 ± 0.016
2.107GlyTyr: 2.107 ± 0.025
0.0GlyXaa: 0.0 ± 0.0
His
2.009HisAla: 2.009 ± 0.022
0.336HisCys: 0.336 ± 0.009
1.454HisAsp: 1.454 ± 0.021
1.388HisGlu: 1.388 ± 0.017
0.921HisPhe: 0.921 ± 0.013
1.864HisGly: 1.864 ± 0.022
0.9HisHis: 0.9 ± 0.017
1.163HisIle: 1.163 ± 0.016
0.903HisLys: 0.903 ± 0.014
2.249HisLeu: 2.249 ± 0.022
0.525HisMet: 0.525 ± 0.01
0.838HisAsn: 0.838 ± 0.012
1.649HisPro: 1.649 ± 0.02
1.03HisGln: 1.03 ± 0.016
1.59HisArg: 1.59 ± 0.019
1.788HisSer: 1.788 ± 0.023
1.222HisThr: 1.222 ± 0.016
1.584HisVal: 1.584 ± 0.018
0.345HisTrp: 0.345 ± 0.01
0.694HisTyr: 0.694 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.077IleAla: 4.077 ± 0.036
0.704IleCys: 0.704 ± 0.013
2.791IleAsp: 2.791 ± 0.022
2.755IleGlu: 2.755 ± 0.026
1.871IlePhe: 1.871 ± 0.021
3.061IleGly: 3.061 ± 0.026
1.16IleHis: 1.16 ± 0.016
2.365IleIle: 2.365 ± 0.024
2.0IleLys: 2.0 ± 0.022
4.322IleLeu: 4.322 ± 0.033
1.051IleMet: 1.051 ± 0.015
1.733IleAsn: 1.733 ± 0.02
2.859IlePro: 2.859 ± 0.026
1.816IleGln: 1.816 ± 0.02
2.771IleArg: 2.771 ± 0.024
3.563IleSer: 3.563 ± 0.03
2.722IleThr: 2.722 ± 0.036
3.15IleVal: 3.15 ± 0.026
0.703IleTrp: 0.703 ± 0.013
1.298IleTyr: 1.298 ± 0.017
0.001IleXaa: 0.001 ± 0.0
Lys
4.096LysAla: 4.096 ± 0.039
0.437LysCys: 0.437 ± 0.01
2.637LysAsp: 2.637 ± 0.029
2.998LysGlu: 2.998 ± 0.036
1.325LysPhe: 1.325 ± 0.018
2.69LysGly: 2.69 ± 0.028
1.111LysHis: 1.111 ± 0.014
2.052LysIle: 2.052 ± 0.023
2.968LysLys: 2.968 ± 0.046
3.879LysLeu: 3.879 ± 0.032
0.958LysMet: 0.958 ± 0.013
1.501LysAsn: 1.501 ± 0.02
2.613LysPro: 2.613 ± 0.029
1.777LysGln: 1.777 ± 0.021
3.179LysArg: 3.179 ± 0.029
3.163LysSer: 3.163 ± 0.029
2.688LysThr: 2.688 ± 0.027
2.608LysVal: 2.608 ± 0.025
0.612LysTrp: 0.612 ± 0.012
1.205LysTyr: 1.205 ± 0.017
0.0LysXaa: 0.0 ± 0.0
Leu
8.327LeuAla: 8.327 ± 0.046
1.186LeuCys: 1.186 ± 0.019
5.445LeuAsp: 5.445 ± 0.038
5.525LeuGlu: 5.525 ± 0.041
3.187LeuPhe: 3.187 ± 0.027
6.137LeuGly: 6.137 ± 0.033
2.26LeuHis: 2.26 ± 0.022
3.711LeuIle: 3.711 ± 0.034
3.892LeuLys: 3.892 ± 0.033
8.392LeuLeu: 8.392 ± 0.061
1.803LeuMet: 1.803 ± 0.02
3.001LeuAsn: 3.001 ± 0.024
5.64LeuPro: 5.64 ± 0.049
3.826LeuGln: 3.826 ± 0.034
5.992LeuArg: 5.992 ± 0.047
7.039LeuSer: 7.039 ± 0.043
4.765LeuThr: 4.765 ± 0.035
5.704LeuVal: 5.704 ± 0.042
1.23LeuTrp: 1.23 ± 0.015
2.307LeuTyr: 2.307 ± 0.024
0.001LeuXaa: 0.001 ± 0.0
Met
2.445MetAla: 2.445 ± 0.022
0.243MetCys: 0.243 ± 0.008
1.337MetAsp: 1.337 ± 0.018
1.317MetGlu: 1.317 ± 0.018
0.709MetPhe: 0.709 ± 0.011
1.487MetGly: 1.487 ± 0.018
0.509MetHis: 0.509 ± 0.011
0.945MetIle: 0.945 ± 0.016
0.929MetLys: 0.929 ± 0.012
1.919MetLeu: 1.919 ± 0.021
0.605MetMet: 0.605 ± 0.011
0.796MetAsn: 0.796 ± 0.013
1.371MetPro: 1.371 ± 0.019
0.879MetGln: 0.879 ± 0.013
1.32MetArg: 1.32 ± 0.016
1.87MetSer: 1.87 ± 0.021
1.318MetThr: 1.318 ± 0.018
1.354MetVal: 1.354 ± 0.018
0.271MetTrp: 0.271 ± 0.008
0.538MetTyr: 0.538 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.068AsnAla: 3.068 ± 0.027
0.44AsnCys: 0.44 ± 0.01
1.973AsnAsp: 1.973 ± 0.018
1.92AsnGlu: 1.92 ± 0.022
1.303AsnPhe: 1.303 ± 0.016
2.939AsnGly: 2.939 ± 0.033
0.858AsnHis: 0.858 ± 0.014
1.909AsnIle: 1.909 ± 0.019
1.413AsnLys: 1.413 ± 0.018
3.151AsnLeu: 3.151 ± 0.025
0.85AsnMet: 0.85 ± 0.014
1.421AsnAsn: 1.421 ± 0.02
2.371AsnPro: 2.371 ± 0.025
1.327AsnGln: 1.327 ± 0.018
1.959AsnArg: 1.959 ± 0.021
2.617AsnSer: 2.617 ± 0.026
2.034AsnThr: 2.034 ± 0.024
2.25AsnVal: 2.25 ± 0.024
0.552AsnTrp: 0.552 ± 0.01
1.001AsnTyr: 1.001 ± 0.015
0.001AsnXaa: 0.001 ± 0.0
Pro
5.64ProAla: 5.64 ± 0.048
0.563ProCys: 0.563 ± 0.012
3.392ProAsp: 3.392 ± 0.031
3.753ProGlu: 3.753 ± 0.034
2.05ProPhe: 2.05 ± 0.02
4.222ProGly: 4.222 ± 0.042
1.351ProHis: 1.351 ± 0.017
2.414ProIle: 2.414 ± 0.023
2.476ProLys: 2.476 ± 0.027
4.883ProLeu: 4.883 ± 0.037
1.144ProMet: 1.144 ± 0.016
2.115ProAsn: 2.115 ± 0.023
5.229ProPro: 5.229 ± 0.077
2.461ProGln: 2.461 ± 0.032
3.728ProArg: 3.728 ± 0.029
5.978ProSer: 5.978 ± 0.05
3.963ProThr: 3.963 ± 0.038
3.729ProVal: 3.729 ± 0.032
0.777ProTrp: 0.777 ± 0.012
1.478ProTyr: 1.478 ± 0.021
0.001ProXaa: 0.001 ± 0.001
Gln
3.792GlnAla: 3.792 ± 0.033
0.469GlnCys: 0.469 ± 0.01
2.273GlnAsp: 2.273 ± 0.023
2.374GlnGlu: 2.374 ± 0.024
1.23GlnPhe: 1.23 ± 0.017
2.578GlnGly: 2.578 ± 0.025
1.137GlnHis: 1.137 ± 0.016
1.76GlnIle: 1.76 ± 0.017
1.789GlnLys: 1.789 ± 0.02
3.544GlnLeu: 3.544 ± 0.033
0.88GlnMet: 0.88 ± 0.016
1.427GlnAsn: 1.427 ± 0.019
2.74GlnPro: 2.74 ± 0.033
2.481GlnGln: 2.481 ± 0.046
2.757GlnArg: 2.757 ± 0.028
3.005GlnSer: 3.005 ± 0.028
2.29GlnThr: 2.29 ± 0.024
2.295GlnVal: 2.295 ± 0.02
0.609GlnTrp: 0.609 ± 0.011
1.134GlnTyr: 1.134 ± 0.016
0.001GlnXaa: 0.001 ± 0.0
Arg
5.049ArgAla: 5.049 ± 0.034
0.759ArgCys: 0.759 ± 0.015
3.624ArgAsp: 3.624 ± 0.039
3.761ArgGlu: 3.761 ± 0.035
2.163ArgPhe: 2.163 ± 0.022
3.967ArgGly: 3.967 ± 0.034
1.695ArgHis: 1.695 ± 0.022
2.907ArgIle: 2.907 ± 0.026
3.207ArgLys: 3.207 ± 0.036
5.734ArgLeu: 5.734 ± 0.041
1.363ArgMet: 1.363 ± 0.018
2.329ArgAsn: 2.329 ± 0.021
3.827ArgPro: 3.827 ± 0.034
2.804ArgGln: 2.804 ± 0.029
5.403ArgArg: 5.403 ± 0.051
4.881ArgSer: 4.881 ± 0.037
3.401ArgThr: 3.401 ± 0.031
3.537ArgVal: 3.537 ± 0.026
0.973ArgTrp: 0.973 ± 0.014
1.7ArgTyr: 1.7 ± 0.019
0.001ArgXaa: 0.001 ± 0.0
Ser
6.748SerAla: 6.748 ± 0.044
0.877SerCys: 0.877 ± 0.014
4.187SerAsp: 4.187 ± 0.032
3.915SerGlu: 3.915 ± 0.033
2.956SerPhe: 2.956 ± 0.025
5.51SerGly: 5.51 ± 0.046
1.956SerHis: 1.956 ± 0.02
3.84SerIle: 3.84 ± 0.03
3.351SerLys: 3.351 ± 0.029
7.135SerLeu: 7.135 ± 0.045
1.745SerMet: 1.745 ± 0.02
2.853SerAsn: 2.853 ± 0.028
5.456SerPro: 5.456 ± 0.05
3.276SerGln: 3.276 ± 0.027
5.206SerArg: 5.206 ± 0.042
8.42SerSer: 8.42 ± 0.072
5.392SerThr: 5.392 ± 0.044
4.57SerVal: 4.57 ± 0.029
1.173SerTrp: 1.173 ± 0.016
2.007SerTyr: 2.007 ± 0.019
0.001SerXaa: 0.001 ± 0.0
Thr
5.369ThrAla: 5.369 ± 0.039
0.742ThrCys: 0.742 ± 0.014
2.844ThrAsp: 2.844 ± 0.026
3.095ThrGlu: 3.095 ± 0.03
2.162ThrPhe: 2.162 ± 0.02
4.175ThrGly: 4.175 ± 0.04
1.278ThrHis: 1.278 ± 0.017
2.98ThrIle: 2.98 ± 0.035
2.406ThrLys: 2.406 ± 0.027
5.183ThrLeu: 5.183 ± 0.038
1.264ThrMet: 1.264 ± 0.018
2.055ThrAsn: 2.055 ± 0.022
4.198ThrPro: 4.198 ± 0.04
2.058ThrGln: 2.058 ± 0.02
3.352ThrArg: 3.352 ± 0.025
5.233ThrSer: 5.233 ± 0.046
4.217ThrThr: 4.217 ± 0.057
3.835ThrVal: 3.835 ± 0.046
0.881ThrTrp: 0.881 ± 0.015
1.579ThrTyr: 1.579 ± 0.02
0.0ThrXaa: 0.0 ± 0.0
Val
5.814ValAla: 5.814 ± 0.04
0.814ValCys: 0.814 ± 0.014
3.913ValAsp: 3.913 ± 0.028
3.944ValGlu: 3.944 ± 0.03
2.473ValPhe: 2.473 ± 0.024
4.087ValGly: 4.087 ± 0.03
1.43ValHis: 1.43 ± 0.017
2.854ValIle: 2.854 ± 0.029
2.74ValLys: 2.74 ± 0.026
5.781ValLeu: 5.781 ± 0.042
1.394ValMet: 1.394 ± 0.018
2.206ValAsn: 2.206 ± 0.022
3.799ValPro: 3.799 ± 0.032
2.465ValGln: 2.465 ± 0.024
3.641ValArg: 3.641 ± 0.027
4.634ValSer: 4.634 ± 0.028
3.578ValThr: 3.578 ± 0.035
4.584ValVal: 4.584 ± 0.041
0.916ValTrp: 0.916 ± 0.015
1.691ValTyr: 1.691 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.208TrpAla: 1.208 ± 0.017
0.197TrpCys: 0.197 ± 0.006
0.93TrpAsp: 0.93 ± 0.013
0.874TrpGlu: 0.874 ± 0.015
0.55TrpPhe: 0.55 ± 0.011
0.95TrpGly: 0.95 ± 0.016
0.39TrpHis: 0.39 ± 0.01
0.739TrpIle: 0.739 ± 0.011
0.726TrpLys: 0.726 ± 0.012
1.376TrpLeu: 1.376 ± 0.021
0.371TrpMet: 0.371 ± 0.01
0.631TrpAsn: 0.631 ± 0.011
0.634TrpPro: 0.634 ± 0.012
0.614TrpGln: 0.614 ± 0.011
1.004TrpArg: 1.004 ± 0.017
1.077TrpSer: 1.077 ± 0.017
0.983TrpThr: 0.983 ± 0.014
0.913TrpVal: 0.913 ± 0.013
0.284TrpTrp: 0.284 ± 0.007
0.435TrpTyr: 0.435 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.143TyrAla: 2.143 ± 0.022
0.406TyrCys: 0.406 ± 0.01
1.683TyrAsp: 1.683 ± 0.018
1.537TyrGlu: 1.537 ± 0.019
1.141TyrPhe: 1.141 ± 0.016
2.055TyrGly: 2.055 ± 0.025
0.741TyrHis: 0.741 ± 0.013
1.318TyrIle: 1.318 ± 0.017
1.004TyrLys: 1.004 ± 0.015
2.601TyrLeu: 2.601 ± 0.024
0.635TyrMet: 0.635 ± 0.011
1.06TyrAsn: 1.06 ± 0.017
1.427TyrPro: 1.427 ± 0.021
1.078TyrGln: 1.078 ± 0.014
1.631TyrArg: 1.631 ± 0.019
1.95TyrSer: 1.95 ± 0.02
1.532TyrThr: 1.532 ± 0.021
1.651TyrVal: 1.651 ± 0.018
0.455TyrTrp: 0.455 ± 0.01
0.886TyrTyr: 0.886 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.001XaaLys: 0.001 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.001XaaPro: 0.001 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.001XaaArg: 0.001 ± 0.0
0.001XaaSer: 0.001 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.181XaaXaa: 0.181 ± 0.034
Statistics based on 10676 proteins (5257513 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski