Amino acid dipepetide frequency for Shahe picorna-like virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.627AlaAla: 6.627 ± 0.0
0.947AlaCys: 0.947 ± 0.0
3.787AlaAsp: 3.787 ± 0.0
2.84AlaGlu: 2.84 ± 0.0
1.893AlaPhe: 1.893 ± 0.0
5.68AlaGly: 5.68 ± 0.0
1.578AlaHis: 1.578 ± 0.0
2.524AlaIle: 2.524 ± 0.0
3.471AlaLys: 3.471 ± 0.0
7.258AlaLeu: 7.258 ± 0.0
2.524AlaMet: 2.524 ± 0.0
4.418AlaAsn: 4.418 ± 0.0
6.627AlaPro: 6.627 ± 0.0
0.947AlaGln: 0.947 ± 0.0
4.733AlaArg: 4.733 ± 0.0
7.258AlaSer: 7.258 ± 0.0
4.733AlaThr: 4.733 ± 0.0
5.68AlaVal: 5.68 ± 0.0
2.524AlaTrp: 2.524 ± 0.0
3.156AlaTyr: 3.156 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.893CysAla: 1.893 ± 0.0
1.262CysCys: 1.262 ± 0.0
1.262CysAsp: 1.262 ± 0.0
0.947CysGlu: 0.947 ± 0.0
0.631CysPhe: 0.631 ± 0.0
3.471CysGly: 3.471 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.947CysIle: 0.947 ± 0.0
0.316CysLys: 0.316 ± 0.0
0.631CysLeu: 0.631 ± 0.0
0.631CysMet: 0.631 ± 0.0
0.631CysAsn: 0.631 ± 0.0
1.262CysPro: 1.262 ± 0.0
0.316CysGln: 0.316 ± 0.0
0.947CysArg: 0.947 ± 0.0
1.578CysSer: 1.578 ± 0.0
0.316CysThr: 0.316 ± 0.0
1.893CysVal: 1.893 ± 0.0
0.947CysTrp: 0.947 ± 0.0
0.316CysTyr: 0.316 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.787AspAla: 3.787 ± 0.0
0.947AspCys: 0.947 ± 0.0
3.787AspAsp: 3.787 ± 0.0
3.787AspGlu: 3.787 ± 0.0
2.524AspPhe: 2.524 ± 0.0
5.68AspGly: 5.68 ± 0.0
0.947AspHis: 0.947 ± 0.0
1.578AspIle: 1.578 ± 0.0
1.893AspLys: 1.893 ± 0.0
3.471AspLeu: 3.471 ± 0.0
0.316AspMet: 0.316 ± 0.0
1.578AspAsn: 1.578 ± 0.0
2.524AspPro: 2.524 ± 0.0
1.262AspGln: 1.262 ± 0.0
0.947AspArg: 0.947 ± 0.0
4.102AspSer: 4.102 ± 0.0
3.471AspThr: 3.471 ± 0.0
5.68AspVal: 5.68 ± 0.0
1.262AspTrp: 1.262 ± 0.0
1.893AspTyr: 1.893 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.524GluAla: 2.524 ± 0.0
1.262GluCys: 1.262 ± 0.0
2.84GluAsp: 2.84 ± 0.0
2.209GluGlu: 2.209 ± 0.0
2.84GluPhe: 2.84 ± 0.0
3.156GluGly: 3.156 ± 0.0
1.262GluHis: 1.262 ± 0.0
1.262GluIle: 1.262 ± 0.0
0.0GluLys: 0.0 ± 0.0
4.102GluLeu: 4.102 ± 0.0
1.893GluMet: 1.893 ± 0.0
0.947GluAsn: 0.947 ± 0.0
1.262GluPro: 1.262 ± 0.0
1.893GluGln: 1.893 ± 0.0
2.524GluArg: 2.524 ± 0.0
3.471GluSer: 3.471 ± 0.0
3.471GluThr: 3.471 ± 0.0
4.733GluVal: 4.733 ± 0.0
0.631GluTrp: 0.631 ± 0.0
2.209GluTyr: 2.209 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.418PheAla: 4.418 ± 0.0
0.631PheCys: 0.631 ± 0.0
2.524PheAsp: 2.524 ± 0.0
3.787PheGlu: 3.787 ± 0.0
2.209PhePhe: 2.209 ± 0.0
2.84PheGly: 2.84 ± 0.0
1.578PheHis: 1.578 ± 0.0
2.84PheIle: 2.84 ± 0.0
0.947PheLys: 0.947 ± 0.0
5.996PheLeu: 5.996 ± 0.0
1.578PheMet: 1.578 ± 0.0
0.947PheAsn: 0.947 ± 0.0
2.524PhePro: 2.524 ± 0.0
1.893PheGln: 1.893 ± 0.0
2.84PheArg: 2.84 ± 0.0
5.364PheSer: 5.364 ± 0.0
3.156PheThr: 3.156 ± 0.0
5.68PheVal: 5.68 ± 0.0
0.631PheTrp: 0.631 ± 0.0
0.631PheTyr: 0.631 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.996GlyAla: 5.996 ± 0.0
0.631GlyCys: 0.631 ± 0.0
3.787GlyAsp: 3.787 ± 0.0
3.156GlyGlu: 3.156 ± 0.0
3.156GlyPhe: 3.156 ± 0.0
5.996GlyGly: 5.996 ± 0.0
1.262GlyHis: 1.262 ± 0.0
3.471GlyIle: 3.471 ± 0.0
4.102GlyLys: 4.102 ± 0.0
5.364GlyLeu: 5.364 ± 0.0
1.893GlyMet: 1.893 ± 0.0
2.209GlyAsn: 2.209 ± 0.0
2.524GlyPro: 2.524 ± 0.0
1.578GlyGln: 1.578 ± 0.0
2.524GlyArg: 2.524 ± 0.0
4.418GlySer: 4.418 ± 0.0
3.787GlyThr: 3.787 ± 0.0
7.573GlyVal: 7.573 ± 0.0
1.578GlyTrp: 1.578 ± 0.0
3.156GlyTyr: 3.156 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.524HisAla: 2.524 ± 0.0
0.316HisCys: 0.316 ± 0.0
0.947HisAsp: 0.947 ± 0.0
0.316HisGlu: 0.316 ± 0.0
2.209HisPhe: 2.209 ± 0.0
1.578HisGly: 1.578 ± 0.0
0.947HisHis: 0.947 ± 0.0
0.631HisIle: 0.631 ± 0.0
1.578HisLys: 1.578 ± 0.0
2.209HisLeu: 2.209 ± 0.0
1.262HisMet: 1.262 ± 0.0
1.262HisAsn: 1.262 ± 0.0
0.947HisPro: 0.947 ± 0.0
0.947HisGln: 0.947 ± 0.0
0.947HisArg: 0.947 ± 0.0
1.578HisSer: 1.578 ± 0.0
1.578HisThr: 1.578 ± 0.0
0.947HisVal: 0.947 ± 0.0
0.631HisTrp: 0.631 ± 0.0
0.947HisTyr: 0.947 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.733IleAla: 4.733 ± 0.0
0.631IleCys: 0.631 ± 0.0
2.209IleAsp: 2.209 ± 0.0
1.893IleGlu: 1.893 ± 0.0
3.156IlePhe: 3.156 ± 0.0
2.524IleGly: 2.524 ± 0.0
0.947IleHis: 0.947 ± 0.0
2.524IleIle: 2.524 ± 0.0
0.631IleLys: 0.631 ± 0.0
4.418IleLeu: 4.418 ± 0.0
1.893IleMet: 1.893 ± 0.0
1.578IleAsn: 1.578 ± 0.0
4.102IlePro: 4.102 ± 0.0
0.947IleGln: 0.947 ± 0.0
3.156IleArg: 3.156 ± 0.0
4.733IleSer: 4.733 ± 0.0
3.156IleThr: 3.156 ± 0.0
3.787IleVal: 3.787 ± 0.0
0.316IleTrp: 0.316 ± 0.0
0.631IleTyr: 0.631 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.947LysAla: 0.947 ± 0.0
0.631LysCys: 0.631 ± 0.0
1.262LysAsp: 1.262 ± 0.0
1.893LysGlu: 1.893 ± 0.0
2.524LysPhe: 2.524 ± 0.0
2.209LysGly: 2.209 ± 0.0
0.631LysHis: 0.631 ± 0.0
2.524LysIle: 2.524 ± 0.0
1.262LysLys: 1.262 ± 0.0
4.418LysLeu: 4.418 ± 0.0
1.262LysMet: 1.262 ± 0.0
0.947LysAsn: 0.947 ± 0.0
1.578LysPro: 1.578 ± 0.0
1.578LysGln: 1.578 ± 0.0
3.156LysArg: 3.156 ± 0.0
2.524LysSer: 2.524 ± 0.0
0.631LysThr: 0.631 ± 0.0
1.893LysVal: 1.893 ± 0.0
1.262LysTrp: 1.262 ± 0.0
2.209LysTyr: 2.209 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.836LeuAla: 8.836 ± 0.0
1.262LeuCys: 1.262 ± 0.0
4.418LeuAsp: 4.418 ± 0.0
4.733LeuGlu: 4.733 ± 0.0
4.418LeuPhe: 4.418 ± 0.0
4.102LeuGly: 4.102 ± 0.0
3.471LeuHis: 3.471 ± 0.0
3.471LeuIle: 3.471 ± 0.0
4.733LeuLys: 4.733 ± 0.0
8.836LeuLeu: 8.836 ± 0.0
2.524LeuMet: 2.524 ± 0.0
3.156LeuAsn: 3.156 ± 0.0
4.733LeuPro: 4.733 ± 0.0
3.787LeuGln: 3.787 ± 0.0
3.787LeuArg: 3.787 ± 0.0
6.942LeuSer: 6.942 ± 0.0
4.733LeuThr: 4.733 ± 0.0
6.627LeuVal: 6.627 ± 0.0
1.893LeuTrp: 1.893 ± 0.0
2.524LeuTyr: 2.524 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.524MetAla: 2.524 ± 0.0
0.631MetCys: 0.631 ± 0.0
1.893MetAsp: 1.893 ± 0.0
0.947MetGlu: 0.947 ± 0.0
1.262MetPhe: 1.262 ± 0.0
0.947MetGly: 0.947 ± 0.0
0.947MetHis: 0.947 ± 0.0
1.893MetIle: 1.893 ± 0.0
1.262MetLys: 1.262 ± 0.0
2.524MetLeu: 2.524 ± 0.0
0.631MetMet: 0.631 ± 0.0
2.209MetAsn: 2.209 ± 0.0
1.578MetPro: 1.578 ± 0.0
1.578MetGln: 1.578 ± 0.0
2.524MetArg: 2.524 ± 0.0
1.893MetSer: 1.893 ± 0.0
2.209MetThr: 2.209 ± 0.0
0.631MetVal: 0.631 ± 0.0
0.631MetTrp: 0.631 ± 0.0
1.262MetTyr: 1.262 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.209AsnAla: 2.209 ± 0.0
0.631AsnCys: 0.631 ± 0.0
0.947AsnAsp: 0.947 ± 0.0
1.262AsnGlu: 1.262 ± 0.0
2.524AsnPhe: 2.524 ± 0.0
3.156AsnGly: 3.156 ± 0.0
0.316AsnHis: 0.316 ± 0.0
2.524AsnIle: 2.524 ± 0.0
0.631AsnLys: 0.631 ± 0.0
1.893AsnLeu: 1.893 ± 0.0
0.631AsnMet: 0.631 ± 0.0
0.947AsnAsn: 0.947 ± 0.0
1.893AsnPro: 1.893 ± 0.0
0.316AsnGln: 0.316 ± 0.0
1.893AsnArg: 1.893 ± 0.0
3.787AsnSer: 3.787 ± 0.0
4.102AsnThr: 4.102 ± 0.0
5.996AsnVal: 5.996 ± 0.0
0.631AsnTrp: 0.631 ± 0.0
0.631AsnTyr: 0.631 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.733ProAla: 4.733 ± 0.0
0.947ProCys: 0.947 ± 0.0
1.578ProAsp: 1.578 ± 0.0
2.84ProGlu: 2.84 ± 0.0
3.471ProPhe: 3.471 ± 0.0
2.524ProGly: 2.524 ± 0.0
0.631ProHis: 0.631 ± 0.0
3.156ProIle: 3.156 ± 0.0
1.578ProLys: 1.578 ± 0.0
5.68ProLeu: 5.68 ± 0.0
2.524ProMet: 2.524 ± 0.0
0.947ProAsn: 0.947 ± 0.0
3.787ProPro: 3.787 ± 0.0
0.947ProGln: 0.947 ± 0.0
3.156ProArg: 3.156 ± 0.0
4.418ProSer: 4.418 ± 0.0
4.418ProThr: 4.418 ± 0.0
5.364ProVal: 5.364 ± 0.0
1.893ProTrp: 1.893 ± 0.0
1.262ProTyr: 1.262 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.524GlnAla: 2.524 ± 0.0
0.316GlnCys: 0.316 ± 0.0
2.524GlnAsp: 2.524 ± 0.0
0.947GlnGlu: 0.947 ± 0.0
1.578GlnPhe: 1.578 ± 0.0
1.893GlnGly: 1.893 ± 0.0
1.262GlnHis: 1.262 ± 0.0
1.893GlnIle: 1.893 ± 0.0
0.947GlnLys: 0.947 ± 0.0
3.156GlnLeu: 3.156 ± 0.0
0.631GlnMet: 0.631 ± 0.0
0.316GlnAsn: 0.316 ± 0.0
0.947GlnPro: 0.947 ± 0.0
1.262GlnGln: 1.262 ± 0.0
1.893GlnArg: 1.893 ± 0.0
2.209GlnSer: 2.209 ± 0.0
1.578GlnThr: 1.578 ± 0.0
0.947GlnVal: 0.947 ± 0.0
0.631GlnTrp: 0.631 ± 0.0
0.631GlnTyr: 0.631 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.787ArgAla: 3.787 ± 0.0
2.84ArgCys: 2.84 ± 0.0
1.893ArgAsp: 1.893 ± 0.0
1.262ArgGlu: 1.262 ± 0.0
2.524ArgPhe: 2.524 ± 0.0
3.787ArgGly: 3.787 ± 0.0
1.578ArgHis: 1.578 ± 0.0
3.156ArgIle: 3.156 ± 0.0
0.947ArgLys: 0.947 ± 0.0
6.311ArgLeu: 6.311 ± 0.0
1.578ArgMet: 1.578 ± 0.0
2.84ArgAsn: 2.84 ± 0.0
0.947ArgPro: 0.947 ± 0.0
1.578ArgGln: 1.578 ± 0.0
2.524ArgArg: 2.524 ± 0.0
2.524ArgSer: 2.524 ± 0.0
3.471ArgThr: 3.471 ± 0.0
5.68ArgVal: 5.68 ± 0.0
2.209ArgTrp: 2.209 ± 0.0
2.209ArgTyr: 2.209 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.049SerAla: 5.049 ± 0.0
0.947SerCys: 0.947 ± 0.0
5.364SerAsp: 5.364 ± 0.0
2.524SerGlu: 2.524 ± 0.0
5.68SerPhe: 5.68 ± 0.0
5.996SerGly: 5.996 ± 0.0
1.893SerHis: 1.893 ± 0.0
3.787SerIle: 3.787 ± 0.0
2.84SerLys: 2.84 ± 0.0
5.364SerLeu: 5.364 ± 0.0
2.209SerMet: 2.209 ± 0.0
3.471SerAsn: 3.471 ± 0.0
3.787SerPro: 3.787 ± 0.0
3.156SerGln: 3.156 ± 0.0
3.471SerArg: 3.471 ± 0.0
5.68SerSer: 5.68 ± 0.0
5.364SerThr: 5.364 ± 0.0
8.204SerVal: 8.204 ± 0.0
1.578SerTrp: 1.578 ± 0.0
2.209SerTyr: 2.209 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.733ThrAla: 4.733 ± 0.0
2.524ThrCys: 2.524 ± 0.0
2.524ThrAsp: 2.524 ± 0.0
2.209ThrGlu: 2.209 ± 0.0
3.156ThrPhe: 3.156 ± 0.0
2.524ThrGly: 2.524 ± 0.0
0.947ThrHis: 0.947 ± 0.0
3.471ThrIle: 3.471 ± 0.0
2.209ThrLys: 2.209 ± 0.0
4.418ThrLeu: 4.418 ± 0.0
3.156ThrMet: 3.156 ± 0.0
3.156ThrAsn: 3.156 ± 0.0
4.733ThrPro: 4.733 ± 0.0
0.947ThrGln: 0.947 ± 0.0
4.418ThrArg: 4.418 ± 0.0
5.049ThrSer: 5.049 ± 0.0
4.102ThrThr: 4.102 ± 0.0
5.049ThrVal: 5.049 ± 0.0
0.947ThrTrp: 0.947 ± 0.0
1.893ThrTyr: 1.893 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.258ValAla: 7.258 ± 0.0
1.893ValCys: 1.893 ± 0.0
3.156ValAsp: 3.156 ± 0.0
4.418ValGlu: 4.418 ± 0.0
3.471ValPhe: 3.471 ± 0.0
5.364ValGly: 5.364 ± 0.0
2.524ValHis: 2.524 ± 0.0
2.524ValIle: 2.524 ± 0.0
2.524ValLys: 2.524 ± 0.0
7.889ValLeu: 7.889 ± 0.0
1.262ValMet: 1.262 ± 0.0
4.418ValAsn: 4.418 ± 0.0
8.52ValPro: 8.52 ± 0.0
2.524ValGln: 2.524 ± 0.0
5.049ValArg: 5.049 ± 0.0
7.258ValSer: 7.258 ± 0.0
3.787ValThr: 3.787 ± 0.0
5.049ValVal: 5.049 ± 0.0
1.578ValTrp: 1.578 ± 0.0
3.787ValTyr: 3.787 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.262TrpAla: 1.262 ± 0.0
0.316TrpCys: 0.316 ± 0.0
4.102TrpAsp: 4.102 ± 0.0
0.947TrpGlu: 0.947 ± 0.0
0.947TrpPhe: 0.947 ± 0.0
1.578TrpGly: 1.578 ± 0.0
0.316TrpHis: 0.316 ± 0.0
1.262TrpIle: 1.262 ± 0.0
1.578TrpLys: 1.578 ± 0.0
1.893TrpLeu: 1.893 ± 0.0
0.947TrpMet: 0.947 ± 0.0
0.316TrpAsn: 0.316 ± 0.0
0.631TrpPro: 0.631 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.209TrpArg: 2.209 ± 0.0
1.578TrpSer: 1.578 ± 0.0
0.631TrpThr: 0.631 ± 0.0
1.578TrpVal: 1.578 ± 0.0
0.631TrpTrp: 0.631 ± 0.0
0.947TrpTyr: 0.947 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.84TyrAla: 2.84 ± 0.0
0.631TyrCys: 0.631 ± 0.0
0.631TyrAsp: 0.631 ± 0.0
1.578TyrGlu: 1.578 ± 0.0
2.84TyrPhe: 2.84 ± 0.0
3.156TyrGly: 3.156 ± 0.0
1.262TyrHis: 1.262 ± 0.0
2.524TyrIle: 2.524 ± 0.0
1.893TyrLys: 1.893 ± 0.0
3.156TyrLeu: 3.156 ± 0.0
0.316TyrMet: 0.316 ± 0.0
0.631TyrAsn: 0.631 ± 0.0
0.947TyrPro: 0.947 ± 0.0
0.631TyrGln: 0.631 ± 0.0
0.947TyrArg: 0.947 ± 0.0
2.209TyrSer: 2.209 ± 0.0
3.471TyrThr: 3.471 ± 0.0
1.578TyrVal: 1.578 ± 0.0
1.262TyrTrp: 1.262 ± 0.0
1.262TyrTyr: 1.262 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3170 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski