Amino acid dipepetide frequency for Orchesella cincta (Springtail)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.196AlaAla: 5.196 ± 0.041	1.106AlaCys: 1.106 ± 0.017	2.952AlaAsp: 2.952 ± 0.019	3.813AlaGlu: 3.813 ± 0.027	2.571AlaPhe: 2.571 ± 0.02	3.662AlaGly: 3.662 ± 0.025	1.354AlaHis: 1.354 ± 0.014	3.44AlaIle: 3.44 ± 0.023	3.805AlaLys: 3.805 ± 0.026	5.455AlaLeu: 5.455 ± 0.038	1.46AlaMet: 1.46 ± 0.013	2.766AlaAsn: 2.766 ± 0.017	2.953AlaPro: 2.953 ± 0.027	2.256AlaGln: 2.256 ± 0.02	2.802AlaArg: 2.802 ± 0.019	5.105AlaSer: 5.105 ± 0.028	3.744AlaThr: 3.744 ± 0.024	4.325AlaVal: 4.325 ± 0.031	0.632AlaTrp: 0.632 ± 0.009	1.741AlaTyr: 1.741 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	1.037CysAla: 1.037 ± 0.013	0.545CysCys: 0.545 ± 0.011	1.095CysAsp: 1.095 ± 0.016	1.156CysGlu: 1.156 ± 0.016	0.858CysPhe: 0.858 ± 0.011	1.489CysGly: 1.489 ± 0.021	0.532CysHis: 0.532 ± 0.008	1.083CysIle: 1.083 ± 0.015	1.163CysLys: 1.163 ± 0.017	1.743CysLeu: 1.743 ± 0.016	0.416CysMet: 0.416 ± 0.007	0.925CysAsn: 0.925 ± 0.012	1.147CysPro: 1.147 ± 0.021	0.804CysGln: 0.804 ± 0.013	1.064CysArg: 1.064 ± 0.021	1.674CysSer: 1.674 ± 0.021	1.031CysThr: 1.031 ± 0.015	1.262CysVal: 1.262 ± 0.016	0.266CysTrp: 0.266 ± 0.007	0.616CysTyr: 0.616 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.168AspAla: 3.168 ± 0.022	1.02AspCys: 1.02 ± 0.015	4.02AspAsp: 4.02 ± 0.034	4.412AspGlu: 4.412 ± 0.03	2.457AspPhe: 2.457 ± 0.018	3.411AspGly: 3.411 ± 0.025	1.11AspHis: 1.11 ± 0.012	3.087AspIle: 3.087 ± 0.018	3.038AspLys: 3.038 ± 0.022	4.631AspLeu: 4.631 ± 0.029	1.229AspMet: 1.229 ± 0.012	2.452AspAsn: 2.452 ± 0.021	2.723AspPro: 2.723 ± 0.026	1.656AspGln: 1.656 ± 0.017	2.31AspArg: 2.31 ± 0.022	4.142AspSer: 4.142 ± 0.026	2.541AspThr: 2.541 ± 0.02	3.403AspVal: 3.403 ± 0.019	0.704AspTrp: 0.704 ± 0.008	1.813AspTyr: 1.813 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	3.965GluAla: 3.965 ± 0.029	1.184GluCys: 1.184 ± 0.02	4.154GluAsp: 4.154 ± 0.026	5.94GluGlu: 5.94 ± 0.051	2.502GluPhe: 2.502 ± 0.019	3.336GluGly: 3.336 ± 0.023	1.296GluHis: 1.296 ± 0.012	3.834GluIle: 3.834 ± 0.024	4.812GluLys: 4.812 ± 0.034	5.634GluLeu: 5.634 ± 0.033	1.733GluMet: 1.733 ± 0.016	3.565GluAsn: 3.565 ± 0.022	2.545GluPro: 2.545 ± 0.026	2.38GluGln: 2.38 ± 0.021	3.323GluArg: 3.323 ± 0.023	4.6GluSer: 4.6 ± 0.03	3.7GluThr: 3.7 ± 0.023	3.916GluVal: 3.916 ± 0.026	0.76GluTrp: 0.76 ± 0.011	1.942GluTyr: 1.942 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	2.433PheAla: 2.433 ± 0.018	0.952PheCys: 0.952 ± 0.012	2.267PheAsp: 2.267 ± 0.018	2.453PheGlu: 2.453 ± 0.018	1.863PhePhe: 1.863 ± 0.018	2.869PheGly: 2.869 ± 0.022	1.149PheHis: 1.149 ± 0.013	2.464PheIle: 2.464 ± 0.019	2.32PheLys: 2.32 ± 0.018	4.155PheLeu: 4.155 ± 0.032	1.016PheMet: 1.016 ± 0.011	1.895PheAsn: 1.895 ± 0.015	2.129PhePro: 2.129 ± 0.017	1.851PheGln: 1.851 ± 0.016	2.231PheArg: 2.231 ± 0.017	3.429PheSer: 3.429 ± 0.022	2.335PheThr: 2.335 ± 0.017	2.765PheVal: 2.765 ± 0.021	0.584PheTrp: 0.584 ± 0.009	1.445PheTyr: 1.445 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	3.536GlyAla: 3.536 ± 0.024	1.134GlyCys: 1.134 ± 0.015	3.188GlyAsp: 3.188 ± 0.022	3.476GlyGlu: 3.476 ± 0.026	2.689GlyPhe: 2.689 ± 0.02	5.324GlyGly: 5.324 ± 0.057	1.436GlyHis: 1.436 ± 0.017	3.525GlyIle: 3.525 ± 0.023	3.95GlyLys: 3.95 ± 0.025	4.802GlyLeu: 4.802 ± 0.03	1.464GlyMet: 1.464 ± 0.015	3.145GlyAsn: 3.145 ± 0.022	2.518GlyPro: 2.518 ± 0.032	2.125GlyGln: 2.125 ± 0.02	3.156GlyArg: 3.156 ± 0.025	5.435GlySer: 5.435 ± 0.033	3.445GlyThr: 3.445 ± 0.022	3.815GlyVal: 3.815 ± 0.024	0.783GlyTrp: 0.783 ± 0.01	2.068GlyTyr: 2.068 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.269HisAla: 1.269 ± 0.013	0.543HisCys: 0.543 ± 0.009	1.104HisAsp: 1.104 ± 0.013	1.343HisGlu: 1.343 ± 0.013	1.151HisPhe: 1.151 ± 0.012	1.536HisGly: 1.536 ± 0.015	1.294HisHis: 1.294 ± 0.024	1.3HisIle: 1.3 ± 0.012	1.265HisLys: 1.265 ± 0.014	2.337HisLeu: 2.337 ± 0.019	0.545HisMet: 0.545 ± 0.009	1.12HisAsn: 1.12 ± 0.013	1.476HisPro: 1.476 ± 0.016	1.146HisGln: 1.146 ± 0.013	1.296HisArg: 1.296 ± 0.013	1.989HisSer: 1.989 ± 0.017	1.146HisThr: 1.146 ± 0.013	1.456HisVal: 1.456 ± 0.014	0.304HisTrp: 0.304 ± 0.006	0.848HisTyr: 0.848 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.346IleAla: 3.346 ± 0.025	1.252IleCys: 1.252 ± 0.013	2.789IleAsp: 2.789 ± 0.018	3.15IleGlu: 3.15 ± 0.022	2.596IlePhe: 2.596 ± 0.025	3.096IleGly: 3.096 ± 0.022	1.416IleHis: 1.416 ± 0.015	3.262IleIle: 3.262 ± 0.023	3.128IleLys: 3.128 ± 0.02	5.432IleLeu: 5.432 ± 0.036	1.311IleMet: 1.311 ± 0.014	2.558IleAsn: 2.558 ± 0.019	3.244IlePro: 3.244 ± 0.019	2.317IleGln: 2.317 ± 0.017	2.966IleArg: 2.966 ± 0.019	4.566IleSer: 4.566 ± 0.025	3.168IleThr: 3.168 ± 0.021	3.64IleVal: 3.64 ± 0.024	0.687IleTrp: 0.687 ± 0.011	1.733IleTyr: 1.733 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.743LysAla: 3.743 ± 0.026	1.347LysCys: 1.347 ± 0.017	3.291LysAsp: 3.291 ± 0.023	4.465LysGlu: 4.465 ± 0.034	2.497LysPhe: 2.497 ± 0.019	3.283LysGly: 3.283 ± 0.028	1.431LysHis: 1.431 ± 0.015	3.577LysIle: 3.577 ± 0.024	5.021LysLys: 5.021 ± 0.043	5.83LysLeu: 5.83 ± 0.031	1.644LysMet: 1.644 ± 0.015	3.057LysAsn: 3.057 ± 0.019	3.086LysPro: 3.086 ± 0.025	2.389LysGln: 2.389 ± 0.021	3.717LysArg: 3.717 ± 0.024	4.864LysSer: 4.864 ± 0.03	3.626LysThr: 3.626 ± 0.023	3.724LysVal: 3.724 ± 0.024	0.793LysTrp: 0.793 ± 0.009	2.064LysTyr: 2.064 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	5.537LeuAla: 5.537 ± 0.034	1.766LeuCys: 1.766 ± 0.016	4.478LeuAsp: 4.478 ± 0.028	5.966LeuGlu: 5.966 ± 0.037	3.631LeuPhe: 3.631 ± 0.028	4.913LeuGly: 4.913 ± 0.033	2.243LeuHis: 2.243 ± 0.016	4.73LeuIle: 4.73 ± 0.032	6.141LeuLys: 6.141 ± 0.035	8.457LeuLeu: 8.457 ± 0.05	2.064LeuMet: 2.064 ± 0.018	4.203LeuAsn: 4.203 ± 0.02	4.714LeuPro: 4.714 ± 0.025	4.08LeuGln: 4.08 ± 0.027	4.926LeuArg: 4.926 ± 0.03	6.906LeuSer: 6.906 ± 0.035	4.973LeuThr: 4.973 ± 0.027	5.442LeuVal: 5.442 ± 0.026	1.005LeuTrp: 1.005 ± 0.012	2.557LeuTyr: 2.557 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.565MetAla: 1.565 ± 0.013	0.409MetCys: 0.409 ± 0.008	1.42MetAsp: 1.42 ± 0.014	1.81MetGlu: 1.81 ± 0.015	0.933MetPhe: 0.933 ± 0.013	1.379MetGly: 1.379 ± 0.015	0.499MetHis: 0.499 ± 0.008	1.263MetIle: 1.263 ± 0.014	1.758MetLys: 1.758 ± 0.015	1.965MetLeu: 1.965 ± 0.017	0.737MetMet: 0.737 ± 0.011	1.176MetAsn: 1.176 ± 0.014	1.048MetPro: 1.048 ± 0.012	0.904MetGln: 0.904 ± 0.012	1.178MetArg: 1.178 ± 0.012	1.89MetSer: 1.89 ± 0.017	1.322MetThr: 1.322 ± 0.012	1.324MetVal: 1.324 ± 0.013	0.274MetTrp: 0.274 ± 0.006	0.694MetTyr: 0.694 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.972AsnAla: 2.972 ± 0.023	1.005AsnCys: 1.005 ± 0.014	2.494AsnAsp: 2.494 ± 0.017	3.082AsnGlu: 3.082 ± 0.02	2.157AsnPhe: 2.157 ± 0.017	3.468AsnGly: 3.468 ± 0.028	1.192AsnHis: 1.192 ± 0.014	2.745AsnIle: 2.745 ± 0.02	2.642AsnLys: 2.642 ± 0.021	4.391AsnLeu: 4.391 ± 0.026	1.152AsnMet: 1.152 ± 0.013	2.933AsnAsn: 2.933 ± 0.031	2.736AsnPro: 2.736 ± 0.022	1.95AsnGln: 1.95 ± 0.018	2.278AsnArg: 2.278 ± 0.016	4.236AsnSer: 4.236 ± 0.03	2.509AsnThr: 2.509 ± 0.017	3.158AsnVal: 3.158 ± 0.019	0.598AsnTrp: 0.598 ± 0.009	1.661AsnTyr: 1.661 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	3.039ProAla: 3.039 ± 0.026	0.865ProCys: 0.865 ± 0.023	2.65ProAsp: 2.65 ± 0.019	3.536ProGlu: 3.536 ± 0.026	2.122ProPhe: 2.122 ± 0.019	3.049ProGly: 3.049 ± 0.043	1.181ProHis: 1.181 ± 0.014	2.726ProIle: 2.726 ± 0.022	3.144ProLys: 3.144 ± 0.023	4.006ProLeu: 4.006 ± 0.024	1.05ProMet: 1.05 ± 0.013	2.596ProAsn: 2.596 ± 0.023	4.375ProPro: 4.375 ± 0.059	2.178ProGln: 2.178 ± 0.024	2.316ProArg: 2.316 ± 0.018	4.706ProSer: 4.706 ± 0.037	3.33ProThr: 3.33 ± 0.025	3.433ProVal: 3.433 ± 0.026	0.553ProTrp: 0.553 ± 0.009	1.539ProTyr: 1.539 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	2.293GlnAla: 2.293 ± 0.019	0.797GlnCys: 0.797 ± 0.014	1.87GlnAsp: 1.87 ± 0.015	2.55GlnGlu: 2.55 ± 0.022	1.595GlnPhe: 1.595 ± 0.013	2.04GlnGly: 2.04 ± 0.019	1.076GlnHis: 1.076 ± 0.012	2.241GlnIle: 2.241 ± 0.016	2.502GlnLys: 2.502 ± 0.019	3.73GlnLeu: 3.73 ± 0.025	1.008GlnMet: 1.008 ± 0.013	2.133GlnAsn: 2.133 ± 0.017	2.124GlnPro: 2.124 ± 0.023	2.754GlnGln: 2.754 ± 0.042	2.218GlnArg: 2.218 ± 0.019	2.954GlnSer: 2.954 ± 0.023	2.193GlnThr: 2.193 ± 0.016	2.352GlnVal: 2.352 ± 0.017	0.467GlnTrp: 0.467 ± 0.008	1.213GlnTyr: 1.213 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	2.8ArgAla: 2.8 ± 0.022	0.982ArgCys: 0.982 ± 0.015	2.624ArgAsp: 2.624 ± 0.02	3.106ArgGlu: 3.106 ± 0.024	2.182ArgPhe: 2.182 ± 0.017	2.848ArgGly: 2.848 ± 0.024	1.381ArgHis: 1.381 ± 0.014	2.867ArgIle: 2.867 ± 0.019	3.997ArgLys: 3.997 ± 0.027	4.54ArgLeu: 4.54 ± 0.027	1.26ArgMet: 1.26 ± 0.011	2.811ArgAsn: 2.811 ± 0.021	2.416ArgPro: 2.416 ± 0.023	2.069ArgGln: 2.069 ± 0.017	3.707ArgArg: 3.707 ± 0.028	3.975ArgSer: 3.975 ± 0.032	2.596ArgThr: 2.596 ± 0.019	3.008ArgVal: 3.008 ± 0.019	0.637ArgTrp: 0.637 ± 0.009	1.575ArgTyr: 1.575 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	4.863SerAla: 4.863 ± 0.028	1.589SerCys: 1.589 ± 0.018	4.222SerAsp: 4.222 ± 0.026	4.726SerGlu: 4.726 ± 0.027	3.371SerPhe: 3.371 ± 0.022	5.385SerGly: 5.385 ± 0.035	1.991SerHis: 1.991 ± 0.017	4.224SerIle: 4.224 ± 0.026	4.963SerLys: 4.963 ± 0.034	6.914SerLeu: 6.914 ± 0.031	1.705SerMet: 1.705 ± 0.014	4.134SerAsn: 4.134 ± 0.025	4.566SerPro: 4.566 ± 0.038	3.291SerGln: 3.291 ± 0.023	4.16SerArg: 4.16 ± 0.032	10.465SerSer: 10.465 ± 0.091	5.394SerThr: 5.394 ± 0.039	5.014SerVal: 5.014 ± 0.026	0.938SerTrp: 0.938 ± 0.01	2.376SerTyr: 2.376 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	3.705ThrAla: 3.705 ± 0.022	1.151ThrCys: 1.151 ± 0.017	2.756ThrAsp: 2.756 ± 0.021	3.398ThrGlu: 3.398 ± 0.024	2.488ThrPhe: 2.488 ± 0.016	3.514ThrGly: 3.514 ± 0.023	1.271ThrHis: 1.271 ± 0.012	3.178ThrIle: 3.178 ± 0.022	3.319ThrLys: 3.319 ± 0.021	5.047ThrLeu: 5.047 ± 0.031	1.256ThrMet: 1.256 ± 0.012	2.732ThrAsn: 2.732 ± 0.018	3.36ThrPro: 3.36 ± 0.03	1.994ThrGln: 1.994 ± 0.018	2.567ThrArg: 2.567 ± 0.018	5.269ThrSer: 5.269 ± 0.037	4.375ThrThr: 4.375 ± 0.054	3.84ThrVal: 3.84 ± 0.026	0.652ThrTrp: 0.652 ± 0.009	1.628ThrTyr: 1.628 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	4.247ValAla: 4.247 ± 0.031	1.34ValCys: 1.34 ± 0.016	3.523ValAsp: 3.523 ± 0.021	4.127ValGlu: 4.127 ± 0.025	2.727ValPhe: 2.727 ± 0.023	3.677ValGly: 3.677 ± 0.024	1.495ValHis: 1.495 ± 0.013	3.637ValIle: 3.637 ± 0.024	3.819ValLys: 3.819 ± 0.023	5.692ValLeu: 5.692 ± 0.031	1.431ValMet: 1.431 ± 0.014	2.924ValAsn: 2.924 ± 0.022	3.276ValPro: 3.276 ± 0.02	2.349ValGln: 2.349 ± 0.018	2.891ValArg: 2.891 ± 0.021	4.841ValSer: 4.841 ± 0.026	3.742ValThr: 3.742 ± 0.023	4.56ValVal: 4.56 ± 0.028	0.747ValTrp: 0.747 ± 0.009	1.895ValTyr: 1.895 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.669TrpAla: 0.669 ± 0.009	0.214TrpCys: 0.214 ± 0.006	0.685TrpAsp: 0.685 ± 0.009	0.768TrpGlu: 0.768 ± 0.01	0.517TrpPhe: 0.517 ± 0.009	0.664TrpGly: 0.664 ± 0.011	0.254TrpHis: 0.254 ± 0.006	0.787TrpIle: 0.787 ± 0.01	0.942TrpLys: 0.942 ± 0.01	1.082TrpLeu: 1.082 ± 0.013	0.345TrpMet: 0.345 ± 0.006	0.704TrpAsn: 0.704 ± 0.01	0.448TrpPro: 0.448 ± 0.009	0.4TrpGln: 0.4 ± 0.006	0.673TrpArg: 0.673 ± 0.008	0.876TrpSer: 0.876 ± 0.011	0.727TrpThr: 0.727 ± 0.009	0.687TrpVal: 0.687 ± 0.009	0.185TrpTrp: 0.185 ± 0.005	0.375TrpTyr: 0.375 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.754TyrAla: 1.754 ± 0.014	0.704TyrCys: 0.704 ± 0.01	1.74TyrAsp: 1.74 ± 0.017	1.841TyrGlu: 1.841 ± 0.016	1.701TyrPhe: 1.701 ± 0.016	2.073TyrGly: 2.073 ± 0.021	0.869TyrHis: 0.869 ± 0.01	1.686TyrIle: 1.686 ± 0.017	1.717TyrLys: 1.717 ± 0.015	2.89TyrLeu: 2.89 ± 0.021	0.722TyrMet: 0.722 ± 0.009	1.529TyrAsn: 1.529 ± 0.015	1.513TyrPro: 1.513 ± 0.016	1.218TyrGln: 1.218 ± 0.013	1.603TyrArg: 1.603 ± 0.014	2.372TyrSer: 2.372 ± 0.019	1.604TyrThr: 1.604 ± 0.017	1.816TyrVal: 1.816 ± 0.017	0.432TyrTrp: 0.432 ± 0.009	1.284TyrTyr: 1.284 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 20218 proteins (8574862 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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