Amino acid dipepetide frequency for Pontibacillus halophilus JSM 076056 = DSM 19796

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.948AlaAla: 4.948 ± 0.099
0.501AlaCys: 0.501 ± 0.023
3.158AlaAsp: 3.158 ± 0.056
4.409AlaGlu: 4.409 ± 0.086
3.375AlaPhe: 3.375 ± 0.06
4.732AlaGly: 4.732 ± 0.084
1.426AlaHis: 1.426 ± 0.041
5.435AlaIle: 5.435 ± 0.092
4.002AlaLys: 4.002 ± 0.074
7.31AlaLeu: 7.31 ± 0.101
2.105AlaMet: 2.105 ± 0.054
2.594AlaAsn: 2.594 ± 0.046
2.192AlaPro: 2.192 ± 0.047
2.332AlaGln: 2.332 ± 0.054
2.739AlaArg: 2.739 ± 0.056
4.61AlaSer: 4.61 ± 0.079
4.023AlaThr: 4.023 ± 0.066
5.354AlaVal: 5.354 ± 0.079
0.698AlaTrp: 0.698 ± 0.031
2.612AlaTyr: 2.612 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
0.357CysAla: 0.357 ± 0.021
0.083CysCys: 0.083 ± 0.01
0.327CysAsp: 0.327 ± 0.018
0.385CysGlu: 0.385 ± 0.02
0.258CysPhe: 0.258 ± 0.017
0.56CysGly: 0.56 ± 0.028
0.174CysHis: 0.174 ± 0.013
0.383CysIle: 0.383 ± 0.02
0.269CysLys: 0.269 ± 0.016
0.515CysLeu: 0.515 ± 0.021
0.166CysMet: 0.166 ± 0.012
0.249CysAsn: 0.249 ± 0.016
0.291CysPro: 0.291 ± 0.018
0.197CysGln: 0.197 ± 0.013
0.245CysArg: 0.245 ± 0.016
0.399CysSer: 0.399 ± 0.019
0.365CysThr: 0.365 ± 0.019
0.424CysVal: 0.424 ± 0.021
0.057CysTrp: 0.057 ± 0.007
0.219CysTyr: 0.219 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
3.52AspAla: 3.52 ± 0.061
0.294AspCys: 0.294 ± 0.017
2.766AspAsp: 2.766 ± 0.059
5.228AspGlu: 5.228 ± 0.078
2.176AspPhe: 2.176 ± 0.043
3.753AspGly: 3.753 ± 0.076
1.233AspHis: 1.233 ± 0.037
3.177AspIle: 3.177 ± 0.055
2.576AspLys: 2.576 ± 0.053
5.178AspLeu: 5.178 ± 0.076
1.364AspMet: 1.364 ± 0.037
1.625AspAsn: 1.625 ± 0.046
1.918AspPro: 1.918 ± 0.042
2.303AspGln: 2.303 ± 0.048
2.579AspArg: 2.579 ± 0.052
2.624AspSer: 2.624 ± 0.049
2.711AspThr: 2.711 ± 0.053
4.554AspVal: 4.554 ± 0.064
0.731AspTrp: 0.731 ± 0.033
2.445AspTyr: 2.445 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
6.402GluAla: 6.402 ± 0.097
0.321GluCys: 0.321 ± 0.02
4.656GluAsp: 4.656 ± 0.076
8.891GluGlu: 8.891 ± 0.139
2.438GluPhe: 2.438 ± 0.054
5.419GluGly: 5.419 ± 0.082
1.831GluHis: 1.831 ± 0.046
4.653GluIle: 4.653 ± 0.082
4.923GluLys: 4.923 ± 0.076
7.331GluLeu: 7.331 ± 0.097
2.408GluMet: 2.408 ± 0.051
3.035GluAsn: 3.035 ± 0.059
2.254GluPro: 2.254 ± 0.053
4.371GluGln: 4.371 ± 0.078
4.538GluArg: 4.538 ± 0.075
3.909GluSer: 3.909 ± 0.081
4.366GluThr: 4.366 ± 0.064
5.625GluVal: 5.625 ± 0.086
0.997GluTrp: 0.997 ± 0.034
2.145GluTyr: 2.145 ± 0.048
0.0GluXaa: 0.0 ± 0.0
Phe
2.789PheAla: 2.789 ± 0.063
0.254PheCys: 0.254 ± 0.017
2.228PheAsp: 2.228 ± 0.046
2.718PheGlu: 2.718 ± 0.056
2.182PhePhe: 2.182 ± 0.067
3.417PheGly: 3.417 ± 0.07
1.145PheHis: 1.145 ± 0.036
3.434PheIle: 3.434 ± 0.073
2.054PheLys: 2.054 ± 0.05
4.381PheLeu: 4.381 ± 0.081
1.201PheMet: 1.201 ± 0.034
1.704PheAsn: 1.704 ± 0.046
1.613PhePro: 1.613 ± 0.038
1.868PheGln: 1.868 ± 0.037
1.604PheArg: 1.604 ± 0.039
2.95PheSer: 2.95 ± 0.057
2.816PheThr: 2.816 ± 0.057
3.217PheVal: 3.217 ± 0.067
0.469PheTrp: 0.469 ± 0.024
1.666PheTyr: 1.666 ± 0.042
0.0PheXaa: 0.0 ± 0.0
Gly
4.941GlyAla: 4.941 ± 0.093
0.539GlyCys: 0.539 ± 0.024
3.593GlyAsp: 3.593 ± 0.06
5.271GlyGlu: 5.271 ± 0.074
3.385GlyPhe: 3.385 ± 0.06
4.988GlyGly: 4.988 ± 0.099
1.408GlyHis: 1.408 ± 0.046
5.402GlyIle: 5.402 ± 0.09
4.303GlyLys: 4.303 ± 0.062
6.573GlyLeu: 6.573 ± 0.102
2.297GlyMet: 2.297 ± 0.047
2.602GlyAsn: 2.602 ± 0.054
1.762GlyPro: 1.762 ± 0.037
2.409GlyGln: 2.409 ± 0.051
2.886GlyArg: 2.886 ± 0.058
4.153GlySer: 4.153 ± 0.071
4.216GlyThr: 4.216 ± 0.072
5.799GlyVal: 5.799 ± 0.09
0.848GlyTrp: 0.848 ± 0.032
3.034GlyTyr: 3.034 ± 0.061
0.0GlyXaa: 0.0 ± 0.0
His
1.575HisAla: 1.575 ± 0.048
0.202HisCys: 0.202 ± 0.014
1.205HisAsp: 1.205 ± 0.037
1.794HisGlu: 1.794 ± 0.044
1.001HisPhe: 1.001 ± 0.03
1.469HisGly: 1.469 ± 0.043
0.786HisHis: 0.786 ± 0.027
1.482HisIle: 1.482 ± 0.04
1.054HisLys: 1.054 ± 0.033
2.346HisLeu: 2.346 ± 0.055
0.62HisMet: 0.62 ± 0.026
0.876HisAsn: 0.876 ± 0.028
1.287HisPro: 1.287 ± 0.035
0.953HisGln: 0.953 ± 0.031
1.042HisArg: 1.042 ± 0.032
1.353HisSer: 1.353 ± 0.044
1.266HisThr: 1.266 ± 0.033
1.798HisVal: 1.798 ± 0.045
0.248HisTrp: 0.248 ± 0.016
1.076HisTyr: 1.076 ± 0.038
0.0HisXaa: 0.0 ± 0.0
Ile
5.247IleAla: 5.247 ± 0.083
0.405IleCys: 0.405 ± 0.019
3.686IleAsp: 3.686 ± 0.056
5.219IleGlu: 5.219 ± 0.077
2.628IlePhe: 2.628 ± 0.063
5.778IleGly: 5.778 ± 0.093
1.743IleHis: 1.743 ± 0.043
4.205IleIle: 4.205 ± 0.083
3.109IleLys: 3.109 ± 0.053
6.158IleLeu: 6.158 ± 0.103
1.628IleMet: 1.628 ± 0.043
2.39IleAsn: 2.39 ± 0.051
3.048IlePro: 3.048 ± 0.063
3.151IleGln: 3.151 ± 0.054
2.975IleArg: 2.975 ± 0.057
4.108IleSer: 4.108 ± 0.076
3.763IleThr: 3.763 ± 0.077
5.417IleVal: 5.417 ± 0.078
0.593IleTrp: 0.593 ± 0.028
2.184IleTyr: 2.184 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
3.925LysAla: 3.925 ± 0.069
0.195LysCys: 0.195 ± 0.014
3.516LysAsp: 3.516 ± 0.062
6.494LysGlu: 6.494 ± 0.099
1.532LysPhe: 1.532 ± 0.044
4.209LysGly: 4.209 ± 0.069
1.356LysHis: 1.356 ± 0.042
2.667LysIle: 2.667 ± 0.052
3.994LysLys: 3.994 ± 0.068
4.63LysLeu: 4.63 ± 0.069
1.57LysMet: 1.57 ± 0.04
2.099LysAsn: 2.099 ± 0.047
1.944LysPro: 1.944 ± 0.045
3.04LysGln: 3.04 ± 0.06
3.492LysArg: 3.492 ± 0.058
2.999LysSer: 2.999 ± 0.06
2.83LysThr: 2.83 ± 0.053
3.936LysVal: 3.936 ± 0.068
0.776LysTrp: 0.776 ± 0.029
1.518LysTyr: 1.518 ± 0.037
0.0LysXaa: 0.0 ± 0.0
Leu
6.957LeuAla: 6.957 ± 0.088
0.6LeuCys: 0.6 ± 0.026
4.934LeuAsp: 4.934 ± 0.071
6.507LeuGlu: 6.507 ± 0.099
4.89LeuPhe: 4.89 ± 0.091
6.473LeuGly: 6.473 ± 0.094
2.347LeuHis: 2.347 ± 0.05
6.397LeuIle: 6.397 ± 0.1
5.218LeuLys: 5.218 ± 0.071
10.455LeuLeu: 10.455 ± 0.148
2.599LeuMet: 2.599 ± 0.048
4.051LeuAsn: 4.051 ± 0.065
4.088LeuPro: 4.088 ± 0.063
4.12LeuGln: 4.12 ± 0.077
3.877LeuArg: 3.877 ± 0.063
7.168LeuSer: 7.168 ± 0.09
5.877LeuThr: 5.877 ± 0.083
6.741LeuVal: 6.741 ± 0.088
0.868LeuTrp: 0.868 ± 0.034
3.378LeuTyr: 3.378 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
2.071MetAla: 2.071 ± 0.052
0.125MetCys: 0.125 ± 0.01
1.625MetAsp: 1.625 ± 0.036
2.192MetGlu: 2.192 ± 0.046
1.083MetPhe: 1.083 ± 0.034
1.879MetGly: 1.879 ± 0.041
0.452MetHis: 0.452 ± 0.02
1.844MetIle: 1.844 ± 0.045
2.435MetLys: 2.435 ± 0.047
2.603MetLeu: 2.603 ± 0.056
0.911MetMet: 0.911 ± 0.035
1.792MetAsn: 1.792 ± 0.047
0.984MetPro: 0.984 ± 0.032
0.933MetGln: 0.933 ± 0.028
1.199MetArg: 1.199 ± 0.038
1.837MetSer: 1.837 ± 0.046
1.722MetThr: 1.722 ± 0.041
1.875MetVal: 1.875 ± 0.044
0.212MetTrp: 0.212 ± 0.014
0.794MetTyr: 0.794 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
2.447AsnAla: 2.447 ± 0.049
0.217AsnCys: 0.217 ± 0.015
2.222AsnAsp: 2.222 ± 0.047
3.81AsnGlu: 3.81 ± 0.058
1.382AsnPhe: 1.382 ± 0.042
3.222AsnGly: 3.222 ± 0.061
1.071AsnHis: 1.071 ± 0.032
2.368AsnIle: 2.368 ± 0.05
2.186AsnLys: 2.186 ± 0.052
3.475AsnLeu: 3.475 ± 0.058
1.071AsnMet: 1.071 ± 0.033
1.514AsnAsn: 1.514 ± 0.046
1.893AsnPro: 1.893 ± 0.045
1.962AsnGln: 1.962 ± 0.047
2.142AsnArg: 2.142 ± 0.045
1.884AsnSer: 1.884 ± 0.053
1.946AsnThr: 1.946 ± 0.046
3.098AsnVal: 3.098 ± 0.054
0.478AsnTrp: 0.478 ± 0.02
1.42AsnTyr: 1.42 ± 0.042
0.0AsnXaa: 0.0 ± 0.0
Pro
2.159ProAla: 2.159 ± 0.048
0.207ProCys: 0.207 ± 0.014
2.05ProAsp: 2.05 ± 0.044
2.877ProGlu: 2.877 ± 0.051
2.068ProPhe: 2.068 ± 0.052
2.267ProGly: 2.267 ± 0.058
0.928ProHis: 0.928 ± 0.032
2.742ProIle: 2.742 ± 0.058
1.939ProLys: 1.939 ± 0.041
3.573ProLeu: 3.573 ± 0.064
0.913ProMet: 0.913 ± 0.03
1.763ProAsn: 1.763 ± 0.04
1.034ProPro: 1.034 ± 0.04
1.12ProGln: 1.12 ± 0.032
1.18ProArg: 1.18 ± 0.031
2.633ProSer: 2.633 ± 0.05
2.265ProThr: 2.265 ± 0.045
2.825ProVal: 2.825 ± 0.052
0.394ProTrp: 0.394 ± 0.019
1.653ProTyr: 1.653 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
3.027GlnAla: 3.027 ± 0.063
0.183GlnCys: 0.183 ± 0.015
2.096GlnAsp: 2.096 ± 0.043
3.425GlnGlu: 3.425 ± 0.066
1.69GlnPhe: 1.69 ± 0.043
2.412GlnGly: 2.412 ± 0.048
1.045GlnHis: 1.045 ± 0.034
2.347GlnIle: 2.347 ± 0.05
2.311GlnLys: 2.311 ± 0.047
4.642GlnLeu: 4.642 ± 0.068
1.225GlnMet: 1.225 ± 0.036
1.572GlnAsn: 1.572 ± 0.043
1.559GlnPro: 1.559 ± 0.04
2.631GlnGln: 2.631 ± 0.063
1.834GlnArg: 1.834 ± 0.047
2.926GlnSer: 2.926 ± 0.061
2.181GlnThr: 2.181 ± 0.042
2.672GlnVal: 2.672 ± 0.054
0.531GlnTrp: 0.531 ± 0.024
1.57GlnTyr: 1.57 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
2.618ArgAla: 2.618 ± 0.055
0.252ArgCys: 0.252 ± 0.016
2.284ArgAsp: 2.284 ± 0.051
3.58ArgGlu: 3.58 ± 0.073
1.978ArgPhe: 1.978 ± 0.046
2.607ArgGly: 2.607 ± 0.05
0.963ArgHis: 0.963 ± 0.029
3.152ArgIle: 3.152 ± 0.057
3.047ArgLys: 3.047 ± 0.058
4.267ArgLeu: 4.267 ± 0.066
1.411ArgMet: 1.411 ± 0.037
2.002ArgAsn: 2.002 ± 0.048
1.434ArgPro: 1.434 ± 0.039
1.746ArgGln: 1.746 ± 0.046
2.098ArgArg: 2.098 ± 0.053
2.567ArgSer: 2.567 ± 0.054
2.641ArgThr: 2.641 ± 0.052
3.096ArgVal: 3.096 ± 0.057
0.433ArgTrp: 0.433 ± 0.021
1.81ArgTyr: 1.81 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
3.539SerAla: 3.539 ± 0.066
0.352SerCys: 0.352 ± 0.018
2.869SerAsp: 2.869 ± 0.059
4.31SerGlu: 4.31 ± 0.079
3.242SerPhe: 3.242 ± 0.057
4.486SerGly: 4.486 ± 0.07
1.407SerHis: 1.407 ± 0.039
5.095SerIle: 5.095 ± 0.072
3.419SerLys: 3.419 ± 0.064
6.366SerLeu: 6.366 ± 0.089
2.017SerMet: 2.017 ± 0.044
2.494SerAsn: 2.494 ± 0.056
2.148SerPro: 2.148 ± 0.046
2.253SerGln: 2.253 ± 0.047
2.338SerArg: 2.338 ± 0.048
4.309SerSer: 4.309 ± 0.069
3.523SerThr: 3.523 ± 0.055
4.573SerVal: 4.573 ± 0.07
0.596SerTrp: 0.596 ± 0.023
2.584SerTyr: 2.584 ± 0.053
0.0SerXaa: 0.0 ± 0.0
Thr
3.789ThrAla: 3.789 ± 0.058
0.34ThrCys: 0.34 ± 0.018
2.728ThrAsp: 2.728 ± 0.055
3.905ThrGlu: 3.905 ± 0.059
2.862ThrPhe: 2.862 ± 0.059
4.141ThrGly: 4.141 ± 0.073
1.235ThrHis: 1.235 ± 0.035
4.564ThrIle: 4.564 ± 0.074
3.143ThrLys: 3.143 ± 0.051
5.752ThrLeu: 5.752 ± 0.078
1.54ThrMet: 1.54 ± 0.036
2.376ThrAsn: 2.376 ± 0.05
2.485ThrPro: 2.485 ± 0.048
1.625ThrGln: 1.625 ± 0.041
2.015ThrArg: 2.015 ± 0.05
3.782ThrSer: 3.782 ± 0.068
3.394ThrThr: 3.394 ± 0.072
4.573ThrVal: 4.573 ± 0.071
0.581ThrTrp: 0.581 ± 0.025
2.439ThrTyr: 2.439 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
5.32ValAla: 5.32 ± 0.083
0.514ValCys: 0.514 ± 0.026
4.115ValAsp: 4.115 ± 0.066
5.574ValGlu: 5.574 ± 0.079
3.227ValPhe: 3.227 ± 0.066
5.184ValGly: 5.184 ± 0.078
1.738ValHis: 1.738 ± 0.039
5.07ValIle: 5.07 ± 0.088
4.115ValLys: 4.115 ± 0.064
7.305ValLeu: 7.305 ± 0.091
2.091ValMet: 2.091 ± 0.043
3.063ValAsn: 3.063 ± 0.059
2.925ValPro: 2.925 ± 0.058
3.047ValGln: 3.047 ± 0.059
3.088ValArg: 3.088 ± 0.055
4.901ValSer: 4.901 ± 0.074
4.684ValThr: 4.684 ± 0.086
5.953ValVal: 5.953 ± 0.084
0.726ValTrp: 0.726 ± 0.028
2.52ValTyr: 2.52 ± 0.052
0.0ValXaa: 0.0 ± 0.0
Trp
0.622TrpAla: 0.622 ± 0.03
0.067TrpCys: 0.067 ± 0.008
0.537TrpAsp: 0.537 ± 0.025
0.731TrpGlu: 0.731 ± 0.031
0.596TrpPhe: 0.596 ± 0.026
0.703TrpGly: 0.703 ± 0.028
0.206TrpHis: 0.206 ± 0.013
0.824TrpIle: 0.824 ± 0.032
0.747TrpLys: 0.747 ± 0.029
1.222TrpLeu: 1.222 ± 0.038
0.403TrpMet: 0.403 ± 0.02
0.539TrpAsn: 0.539 ± 0.025
0.253TrpPro: 0.253 ± 0.018
0.361TrpGln: 0.361 ± 0.018
0.386TrpArg: 0.386 ± 0.018
0.631TrpSer: 0.631 ± 0.026
0.653TrpThr: 0.653 ± 0.023
0.818TrpVal: 0.818 ± 0.03
0.176TrpTrp: 0.176 ± 0.013
0.38TrpTyr: 0.38 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.301TyrAla: 2.301 ± 0.049
0.273TyrCys: 0.273 ± 0.016
2.164TyrAsp: 2.164 ± 0.049
3.19TyrGlu: 3.19 ± 0.058
1.717TyrPhe: 1.717 ± 0.04
2.712TyrGly: 2.712 ± 0.06
0.939TyrHis: 0.939 ± 0.03
2.192TyrIle: 2.192 ± 0.054
1.878TyrLys: 1.878 ± 0.046
3.466TyrLeu: 3.466 ± 0.059
1.028TyrMet: 1.028 ± 0.032
1.468TyrAsn: 1.468 ± 0.045
1.477TyrPro: 1.477 ± 0.041
1.457TyrGln: 1.457 ± 0.041
1.727TyrArg: 1.727 ± 0.038
2.176TyrSer: 2.176 ± 0.04
2.029TyrThr: 2.029 ± 0.051
2.812TyrVal: 2.812 ± 0.049
0.444TyrTrp: 0.444 ± 0.023
1.517TyrTyr: 1.517 ± 0.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3559 proteins (1015912 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski