Amino acid dipepetide frequency for Prunus virus T

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.94AlaAla: 2.94 ± 1.089
2.1AlaCys: 2.1 ± 2.149
2.94AlaAsp: 2.94 ± 0.366
4.2AlaGlu: 4.2 ± 1.358
2.52AlaPhe: 2.52 ± 0.953
2.52AlaGly: 2.52 ± 1.324
1.26AlaHis: 1.26 ± 0.662
2.94AlaIle: 2.94 ± 0.95
3.78AlaLys: 3.78 ± 1.619
5.46AlaLeu: 5.46 ± 3.494
0.0AlaMet: 0.0 ± 0.613
0.84AlaAsn: 0.84 ± 0.661
2.1AlaPro: 2.1 ± 0.683
2.52AlaGln: 2.52 ± 1.577
3.36AlaArg: 3.36 ± 1.765
4.2AlaSer: 4.2 ± 1.367
2.52AlaThr: 2.52 ± 2.181
3.36AlaVal: 3.36 ± 1.686
0.0AlaTrp: 0.0 ± 0.0
2.52AlaTyr: 2.52 ± 2.547
0.0AlaXaa: 0.0 ± 0.0
Cys
2.1CysAla: 2.1 ± 0.484
0.84CysCys: 0.84 ± 0.661
1.26CysAsp: 1.26 ± 0.662
0.84CysGlu: 0.84 ± 0.661
3.36CysPhe: 3.36 ± 0.336
1.68CysGly: 1.68 ± 0.883
0.84CysHis: 0.84 ± 0.661
0.84CysIle: 0.84 ± 0.441
0.84CysLys: 0.84 ± 0.849
2.94CysLeu: 2.94 ± 0.95
1.68CysMet: 1.68 ± 0.452
1.26CysAsn: 1.26 ± 0.662
0.42CysPro: 0.42 ± 0.221
0.0CysGln: 0.0 ± 0.0
1.26CysArg: 1.26 ± 0.662
1.26CysSer: 1.26 ± 0.521
0.84CysThr: 0.84 ± 0.441
1.68CysVal: 1.68 ± 0.787
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.36AspAla: 3.36 ± 1.319
1.68AspCys: 1.68 ± 0.883
3.78AspAsp: 3.78 ± 0.91
5.04AspGlu: 5.04 ± 2.648
3.78AspPhe: 3.78 ± 0.436
3.78AspGly: 3.78 ± 1.564
2.52AspHis: 2.52 ± 1.308
1.26AspIle: 1.26 ± 0.662
2.1AspLys: 2.1 ± 0.484
2.94AspLeu: 2.94 ± 0.765
1.26AspMet: 1.26 ± 0.662
2.94AspAsn: 2.94 ± 1.827
3.36AspPro: 3.36 ± 1.26
2.1AspGln: 2.1 ± 1.624
2.52AspArg: 2.52 ± 1.324
3.36AspSer: 3.36 ± 1.686
3.36AspThr: 3.36 ± 0.904
3.78AspVal: 3.78 ± 1.215
1.68AspTrp: 1.68 ± 0.452
2.52AspTyr: 2.52 ± 0.601
0.0AspXaa: 0.0 ± 0.0
Glu
3.78GluAla: 3.78 ± 1.619
2.1GluCys: 2.1 ± 1.103
3.78GluAsp: 3.78 ± 0.436
8.82GluGlu: 8.82 ± 2.01
8.4GluPhe: 8.4 ± 1.705
8.4GluGly: 8.4 ± 2.711
1.26GluHis: 1.26 ± 0.521
3.36GluIle: 3.36 ± 0.953
7.56GluLys: 7.56 ± 1.35
4.62GluLeu: 4.62 ± 0.797
1.68GluMet: 1.68 ± 1.698
3.78GluAsn: 3.78 ± 1.439
2.94GluPro: 2.94 ± 0.765
3.36GluGln: 3.36 ± 0.336
5.04GluArg: 5.04 ± 1.123
6.72GluSer: 6.72 ± 0.911
1.26GluThr: 1.26 ± 0.662
5.04GluVal: 5.04 ± 2.362
0.42GluTrp: 0.42 ± 0.221
1.68GluTyr: 1.68 ± 0.883
0.0GluXaa: 0.0 ± 0.0
Phe
3.78PheAla: 3.78 ± 0.436
1.26PheCys: 1.26 ± 0.662
5.46PheAsp: 5.46 ± 0.89
5.04PheGlu: 5.04 ± 1.002
2.94PhePhe: 2.94 ± 1.095
4.2PheGly: 4.2 ± 1.629
2.1PheHis: 2.1 ± 0.484
0.84PheIle: 0.84 ± 0.441
6.3PheLys: 6.3 ± 0.667
7.98PheLeu: 7.98 ± 1.57
2.1PheMet: 2.1 ± 1.103
1.68PheAsn: 1.68 ± 0.787
3.36PhePro: 3.36 ± 0.87
0.84PheGln: 0.84 ± 0.661
3.36PheArg: 3.36 ± 0.87
7.14PheSer: 7.14 ± 1.677
2.52PheThr: 2.52 ± 1.324
2.94PheVal: 2.94 ± 1.451
0.84PheTrp: 0.84 ± 0.441
0.84PheTyr: 0.84 ± 0.441
0.0PheXaa: 0.0 ± 0.0
Gly
2.94GlyAla: 2.94 ± 1.972
2.52GlyCys: 2.52 ± 0.601
2.52GlyAsp: 2.52 ± 0.502
7.56GlyGlu: 7.56 ± 0.414
2.52GlyPhe: 2.52 ± 0.601
4.2GlyGly: 4.2 ± 0.437
0.84GlyHis: 0.84 ± 0.441
2.52GlyIle: 2.52 ± 0.601
4.2GlyLys: 4.2 ± 0.968
5.88GlyLeu: 5.88 ± 1.898
2.1GlyMet: 2.1 ± 0.484
1.68GlyAsn: 1.68 ± 0.883
1.68GlyPro: 1.68 ± 1.321
2.1GlyGln: 2.1 ± 1.767
5.46GlyArg: 5.46 ± 2.929
7.14GlySer: 7.14 ± 2.21
3.78GlyThr: 3.78 ± 1.564
2.94GlyVal: 2.94 ± 0.95
1.68GlyTrp: 1.68 ± 0.787
2.1GlyTyr: 2.1 ± 1.103
0.0GlyXaa: 0.0 ± 0.0
His
2.1HisAla: 2.1 ± 0.683
0.0HisCys: 0.0 ± 0.0
2.52HisAsp: 2.52 ± 1.043
1.26HisGlu: 1.26 ± 0.662
1.26HisPhe: 1.26 ± 0.521
1.68HisGly: 1.68 ± 0.787
0.84HisHis: 0.84 ± 0.441
1.26HisIle: 1.26 ± 1.091
0.84HisLys: 0.84 ± 0.441
3.36HisLeu: 3.36 ± 1.765
0.42HisMet: 0.42 ± 0.221
0.42HisAsn: 0.42 ± 0.221
1.68HisPro: 1.68 ± 0.883
1.26HisGln: 1.26 ± 0.662
0.84HisArg: 0.84 ± 0.441
1.26HisSer: 1.26 ± 0.521
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.26HisTrp: 1.26 ± 0.662
1.26HisTyr: 1.26 ± 0.662
0.0HisXaa: 0.0 ± 0.0
Ile
4.2IleAla: 4.2 ± 1.367
0.42IleCys: 0.42 ± 0.836
3.36IleAsp: 3.36 ± 0.953
2.94IleGlu: 2.94 ± 0.765
2.1IlePhe: 2.1 ± 0.683
2.52IleGly: 2.52 ± 0.953
1.68IleHis: 1.68 ± 0.883
1.26IleIle: 1.26 ± 0.662
3.36IleLys: 3.36 ± 0.953
3.36IleLeu: 3.36 ± 1.765
0.84IleMet: 0.84 ± 0.395
2.1IleAsn: 2.1 ± 1.103
1.68IlePro: 1.68 ± 0.883
2.1IleGln: 2.1 ± 1.17
4.2IleArg: 4.2 ± 1.465
5.88IleSer: 5.88 ± 1.901
2.52IleThr: 2.52 ± 0.953
2.1IleVal: 2.1 ± 1.17
0.0IleTrp: 0.0 ± 0.0
2.1IleTyr: 2.1 ± 0.484
0.0IleXaa: 0.0 ± 0.0
Lys
2.94LysAla: 2.94 ± 1.56
0.42LysCys: 0.42 ± 0.221
2.1LysAsp: 2.1 ± 0.484
8.4LysGlu: 8.4 ± 1.208
2.1LysPhe: 2.1 ± 0.846
5.04LysGly: 5.04 ± 0.121
1.26LysHis: 1.26 ± 0.789
2.52LysIle: 2.52 ± 0.601
7.98LysLys: 7.98 ± 2.992
7.14LysLeu: 7.14 ± 1.665
3.36LysMet: 3.36 ± 0.87
3.36LysAsn: 3.36 ± 1.765
2.1LysPro: 2.1 ± 1.767
2.52LysGln: 2.52 ± 0.502
6.72LysArg: 6.72 ± 0.911
3.78LysSer: 3.78 ± 1.152
4.2LysThr: 4.2 ± 0.968
7.14LysVal: 7.14 ± 2.523
0.42LysTrp: 0.42 ± 0.221
0.84LysTyr: 0.84 ± 0.441
0.0LysXaa: 0.0 ± 0.0
Leu
3.78LeuAla: 3.78 ± 1.986
2.94LeuCys: 2.94 ± 1.095
3.36LeuAsp: 3.36 ± 1.26
6.3LeuGlu: 6.3 ± 2.651
5.04LeuPhe: 5.04 ± 1.069
4.2LeuGly: 4.2 ± 1.629
1.68LeuHis: 1.68 ± 0.883
6.3LeuIle: 6.3 ± 0.667
7.14LeuLys: 7.14 ± 2.685
7.98LeuLeu: 7.98 ± 3.066
2.1LeuMet: 2.1 ± 0.484
5.46LeuAsn: 5.46 ± 1.359
3.78LeuPro: 3.78 ± 1.564
2.52LeuGln: 2.52 ± 2.981
7.14LeuArg: 7.14 ± 1.503
5.88LeuSer: 5.88 ± 0.477
5.88LeuThr: 5.88 ± 1.268
4.62LeuVal: 4.62 ± 1.178
0.84LeuTrp: 0.84 ± 0.661
0.84LeuTyr: 0.84 ± 0.441
0.0LeuXaa: 0.0 ± 0.0
Met
0.42MetAla: 0.42 ± 0.221
0.42MetCys: 0.42 ± 0.221
2.1MetAsp: 2.1 ± 0.683
2.94MetGlu: 2.94 ± 0.765
1.68MetPhe: 1.68 ± 0.883
0.84MetGly: 0.84 ± 0.849
0.42MetHis: 0.42 ± 0.221
1.68MetIle: 1.68 ± 0.787
2.1MetLys: 2.1 ± 0.484
1.26MetLeu: 1.26 ± 0.662
0.42MetMet: 0.42 ± 0.221
1.68MetAsn: 1.68 ± 0.883
1.68MetPro: 1.68 ± 0.883
0.84MetGln: 0.84 ± 1.303
2.1MetArg: 2.1 ± 0.846
2.94MetSer: 2.94 ± 1.827
0.84MetThr: 0.84 ± 0.441
1.68MetVal: 1.68 ± 0.883
0.42MetTrp: 0.42 ± 0.221
0.42MetTyr: 0.42 ± 0.221
0.0MetXaa: 0.0 ± 0.0
Asn
1.26AsnAla: 1.26 ± 1.491
0.84AsnCys: 0.84 ± 0.441
1.26AsnAsp: 1.26 ± 0.662
1.68AsnGlu: 1.68 ± 0.787
4.62AsnPhe: 4.62 ± 0.797
1.68AsnGly: 1.68 ± 0.883
1.26AsnHis: 1.26 ± 0.662
2.52AsnIle: 2.52 ± 0.502
3.78AsnLys: 3.78 ± 2.352
5.46AsnLeu: 5.46 ± 2.233
0.42AsnMet: 0.42 ± 0.221
1.68AsnAsn: 1.68 ± 1.698
0.42AsnPro: 0.42 ± 0.221
0.84AsnGln: 0.84 ± 0.441
3.78AsnArg: 3.78 ± 1.152
2.94AsnSer: 2.94 ± 1.544
1.26AsnThr: 1.26 ± 0.662
2.94AsnVal: 2.94 ± 2.087
0.0AsnTrp: 0.0 ± 0.0
2.1AsnTyr: 2.1 ± 1.103
0.0AsnXaa: 0.0 ± 0.0
Pro
1.26ProAla: 1.26 ± 1.091
0.42ProCys: 0.42 ± 0.221
1.68ProAsp: 1.68 ± 0.883
2.52ProGlu: 2.52 ± 1.577
0.84ProPhe: 0.84 ± 1.303
3.36ProGly: 3.36 ± 1.319
1.26ProHis: 1.26 ± 0.662
3.36ProIle: 3.36 ± 0.904
3.36ProLys: 3.36 ± 0.904
1.26ProLeu: 1.26 ± 0.521
0.84ProMet: 0.84 ± 0.661
1.68ProAsn: 1.68 ± 0.883
0.42ProPro: 0.42 ± 0.221
1.26ProGln: 1.26 ± 0.789
2.1ProArg: 2.1 ± 1.17
2.1ProSer: 2.1 ± 0.484
0.42ProThr: 0.42 ± 0.836
3.78ProVal: 3.78 ± 1.152
0.42ProTrp: 0.42 ± 0.221
2.1ProTyr: 2.1 ± 1.17
0.0ProXaa: 0.0 ± 0.0
Gln
1.68GlnAla: 1.68 ± 1.698
0.0GlnCys: 0.0 ± 0.0
2.1GlnAsp: 2.1 ± 0.484
3.36GlnGlu: 3.36 ± 1.26
2.1GlnPhe: 2.1 ± 0.683
2.1GlnGly: 2.1 ± 1.528
0.42GlnHis: 0.42 ± 0.221
2.1GlnIle: 2.1 ± 1.17
1.26GlnLys: 1.26 ± 0.662
2.1GlnLeu: 2.1 ± 1.103
0.84GlnMet: 0.84 ± 0.849
0.0GlnAsn: 0.0 ± 0.0
0.42GlnPro: 0.42 ± 0.221
0.84GlnGln: 0.84 ± 1.303
2.1GlnArg: 2.1 ± 0.683
2.52GlnSer: 2.52 ± 2.3
3.36GlnThr: 3.36 ± 3.496
2.52GlnVal: 2.52 ± 1.577
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.46ArgAla: 5.46 ± 1.353
1.26ArgCys: 1.26 ± 0.521
3.36ArgAsp: 3.36 ± 0.336
5.88ArgGlu: 5.88 ± 0.731
6.72ArgPhe: 6.72 ± 1.858
5.46ArgGly: 5.46 ± 2.929
1.26ArgHis: 1.26 ± 0.789
2.94ArgIle: 2.94 ± 0.765
4.62ArgLys: 4.62 ± 1.394
6.3ArgLeu: 6.3 ± 2.764
1.68ArgMet: 1.68 ± 0.883
2.52ArgAsn: 2.52 ± 1.324
1.26ArgPro: 1.26 ± 0.521
0.42ArgGln: 0.42 ± 0.221
4.62ArgArg: 4.62 ± 3.643
6.3ArgSer: 6.3 ± 1.958
1.68ArgThr: 1.68 ± 0.452
4.62ArgVal: 4.62 ± 1.568
0.42ArgTrp: 0.42 ± 0.221
1.68ArgTyr: 1.68 ± 0.883
0.0ArgXaa: 0.0 ± 0.0
Ser
2.94SerAla: 2.94 ± 1.827
2.1SerCys: 2.1 ± 0.484
7.14SerAsp: 7.14 ± 0.603
7.14SerGlu: 7.14 ± 3.328
6.72SerPhe: 6.72 ± 1.906
4.2SerGly: 4.2 ± 3.517
1.26SerHis: 1.26 ± 0.662
2.94SerIle: 2.94 ± 0.765
6.72SerLys: 6.72 ± 1.546
5.46SerLeu: 5.46 ± 2.397
2.1SerMet: 2.1 ± 1.103
2.94SerAsn: 2.94 ± 1.451
2.1SerPro: 2.1 ± 0.484
2.52SerGln: 2.52 ± 0.601
3.36SerArg: 3.36 ± 0.336
6.72SerSer: 6.72 ± 4.412
2.52SerThr: 2.52 ± 0.601
7.98SerVal: 7.98 ± 3.87
0.42SerTrp: 0.42 ± 0.221
2.1SerTyr: 2.1 ± 1.103
0.0SerXaa: 0.0 ± 0.0
Thr
1.26ThrAla: 1.26 ± 0.521
2.1ThrCys: 2.1 ± 0.683
2.1ThrAsp: 2.1 ± 0.846
3.36ThrGlu: 3.36 ± 2.572
4.62ThrPhe: 4.62 ± 1.568
3.78ThrGly: 3.78 ± 2.486
0.42ThrHis: 0.42 ± 0.221
2.1ThrIle: 2.1 ± 1.17
2.1ThrLys: 2.1 ± 1.624
3.78ThrLeu: 3.78 ± 0.91
1.26ThrMet: 1.26 ± 0.789
1.68ThrAsn: 1.68 ± 0.452
1.68ThrPro: 1.68 ± 0.883
0.84ThrGln: 0.84 ± 0.441
2.94ThrArg: 2.94 ± 0.765
2.52ThrSer: 2.52 ± 0.601
0.42ThrThr: 0.42 ± 0.221
1.68ThrVal: 1.68 ± 0.883
0.42ThrTrp: 0.42 ± 0.221
0.84ThrTyr: 0.84 ± 0.661
0.0ThrXaa: 0.0 ± 0.0
Val
3.36ValAla: 3.36 ± 1.319
1.26ValCys: 1.26 ± 0.789
3.78ValAsp: 3.78 ± 2.352
5.46ValGlu: 5.46 ± 2.868
2.52ValPhe: 2.52 ± 0.953
3.78ValGly: 3.78 ± 3.468
1.68ValHis: 1.68 ± 0.452
5.46ValIle: 5.46 ± 1.994
4.62ValLys: 4.62 ± 0.233
6.72ValLeu: 6.72 ± 0.673
2.52ValMet: 2.52 ± 0.385
4.2ValAsn: 4.2 ± 1.367
2.94ValPro: 2.94 ± 2.087
2.52ValGln: 2.52 ± 2.181
4.2ValArg: 4.2 ± 3.304
3.36ValSer: 3.36 ± 0.336
1.68ValThr: 1.68 ± 0.452
1.68ValVal: 1.68 ± 1.321
0.0ValTrp: 0.0 ± 0.0
0.42ValTyr: 0.42 ± 0.221
0.0ValXaa: 0.0 ± 0.0
Trp
1.26TrpAla: 1.26 ± 0.521
0.42TrpCys: 0.42 ± 0.221
0.84TrpAsp: 0.84 ± 0.441
0.84TrpGlu: 0.84 ± 0.661
0.84TrpPhe: 0.84 ± 0.849
0.42TrpGly: 0.42 ± 0.221
0.0TrpHis: 0.0 ± 0.0
0.84TrpIle: 0.84 ± 0.441
0.0TrpLys: 0.0 ± 0.0
0.42TrpLeu: 0.42 ± 0.221
0.84TrpMet: 0.84 ± 0.441
0.84TrpAsn: 0.84 ± 0.441
0.0TrpPro: 0.0 ± 0.0
0.42TrpGln: 0.42 ± 0.221
0.42TrpArg: 0.42 ± 0.221
0.84TrpSer: 0.84 ± 0.441
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.42TrpTrp: 0.42 ± 0.221
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.68TyrAla: 1.68 ± 0.787
0.84TyrCys: 0.84 ± 0.441
1.68TyrAsp: 1.68 ± 0.883
0.42TyrGlu: 0.42 ± 0.221
0.84TyrPhe: 0.84 ± 0.441
2.52TyrGly: 2.52 ± 1.324
1.26TyrHis: 1.26 ± 0.662
1.68TyrIle: 1.68 ± 0.452
1.68TyrLys: 1.68 ± 0.452
3.36TyrLeu: 3.36 ± 1.26
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.42TyrPro: 0.42 ± 0.221
0.0TyrGln: 0.0 ± 0.0
2.94TyrArg: 2.94 ± 1.095
2.52TyrSer: 2.52 ± 0.601
0.84TyrThr: 0.84 ± 0.441
1.68TyrVal: 1.68 ± 1.321
0.0TyrTrp: 0.0 ± 0.0
0.84TyrTyr: 0.84 ± 0.441
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2382 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski