Amino acid dipepetide frequency for Tacheng Tick Virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.116AlaAla: 7.116 ± 0.968
0.837AlaCys: 0.837 ± 0.353
4.186AlaAsp: 4.186 ± 0.267
2.93AlaGlu: 2.93 ± 0.796
2.093AlaPhe: 2.093 ± 3.18
1.674AlaGly: 1.674 ± 0.706
1.256AlaHis: 1.256 ± 1.502
4.604AlaIle: 4.604 ± 1.94
1.674AlaLys: 1.674 ± 0.706
6.279AlaLeu: 6.279 ± 2.646
1.256AlaMet: 1.256 ± 0.529
1.256AlaAsn: 1.256 ± 1.502
2.093AlaPro: 2.093 ± 5.211
3.767AlaGln: 3.767 ± 0.443
2.512AlaArg: 2.512 ± 3.003
4.186AlaSer: 4.186 ± 1.764
5.023AlaThr: 5.023 ± 2.117
2.512AlaVal: 2.512 ± 1.058
0.837AlaTrp: 0.837 ± 0.353
3.767AlaTyr: 3.767 ± 4.505
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.837CysGlu: 0.837 ± 0.353
1.256CysPhe: 1.256 ± 0.529
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.674CysIle: 1.674 ± 0.706
0.0CysLys: 0.0 ± 0.0
2.512CysLeu: 2.512 ± 1.058
0.0CysMet: 0.0 ± 0.0
0.419CysAsn: 0.419 ± 0.176
1.256CysPro: 1.256 ± 0.529
0.419CysGln: 0.419 ± 0.176
0.419CysArg: 0.419 ± 0.176
2.093CysSer: 2.093 ± 0.882
1.256CysThr: 1.256 ± 0.529
0.837CysVal: 0.837 ± 0.353
0.837CysTrp: 0.837 ± 0.353
0.419CysTyr: 0.419 ± 0.176
0.0CysXaa: 0.0 ± 0.0
Asp
2.093AspAla: 2.093 ± 1.149
0.419AspCys: 0.419 ± 0.176
0.419AspAsp: 0.419 ± 0.176
2.512AspGlu: 2.512 ± 1.058
5.023AspPhe: 5.023 ± 2.117
1.674AspGly: 1.674 ± 1.325
2.093AspHis: 2.093 ± 0.882
2.093AspIle: 2.093 ± 0.882
1.674AspLys: 1.674 ± 0.706
6.279AspLeu: 6.279 ± 0.615
1.256AspMet: 1.256 ± 0.589
1.256AspAsn: 1.256 ± 0.529
3.767AspPro: 3.767 ± 1.588
2.093AspGln: 2.093 ± 3.18
2.93AspArg: 2.93 ± 0.796
2.093AspSer: 2.093 ± 1.149
2.93AspThr: 2.93 ± 0.796
2.512AspVal: 2.512 ± 0.973
1.256AspTrp: 1.256 ± 0.529
1.674AspTyr: 1.674 ± 0.706
0.0AspXaa: 0.0 ± 0.0
Glu
5.023GluAla: 5.023 ± 2.117
1.256GluCys: 1.256 ± 0.529
2.93GluAsp: 2.93 ± 4.858
3.767GluGlu: 3.767 ± 1.588
3.767GluPhe: 3.767 ± 1.588
4.186GluGly: 4.186 ± 2.298
2.512GluHis: 2.512 ± 1.058
4.604GluIle: 4.604 ± 1.94
3.349GluLys: 3.349 ± 1.411
5.86GluLeu: 5.86 ± 1.592
1.256GluMet: 1.256 ± 0.529
2.512GluAsn: 2.512 ± 1.058
1.674GluPro: 1.674 ± 0.706
0.837GluGln: 0.837 ± 0.353
2.93GluArg: 2.93 ± 1.235
2.93GluSer: 2.93 ± 0.796
5.023GluThr: 5.023 ± 1.945
4.604GluVal: 4.604 ± 2.121
1.256GluTrp: 1.256 ± 0.529
1.256GluTyr: 1.256 ± 0.529
0.0GluXaa: 0.0 ± 0.0
Phe
2.512PheAla: 2.512 ± 0.973
0.837PheCys: 0.837 ± 0.353
2.512PheAsp: 2.512 ± 0.973
1.256PheGlu: 1.256 ± 0.529
2.512PhePhe: 2.512 ± 0.973
2.512PheGly: 2.512 ± 0.973
3.349PheHis: 3.349 ± 1.411
2.512PheIle: 2.512 ± 0.973
3.767PheLys: 3.767 ± 1.588
5.86PheLeu: 5.86 ± 0.439
0.419PheMet: 0.419 ± 0.176
0.419PheAsn: 0.419 ± 0.176
2.93PhePro: 2.93 ± 1.235
2.93PheGln: 2.93 ± 0.796
5.023PheArg: 5.023 ± 6.007
4.604PheSer: 4.604 ± 2.121
1.674PheThr: 1.674 ± 0.706
3.767PheVal: 3.767 ± 1.588
1.674PheTrp: 1.674 ± 0.706
1.674PheTyr: 1.674 ± 1.325
0.0PheXaa: 0.0 ± 0.0
Gly
2.512GlyAla: 2.512 ± 1.058
1.256GlyCys: 1.256 ± 0.529
2.093GlyAsp: 2.093 ± 0.882
4.604GlyGlu: 4.604 ± 0.091
3.767GlyPhe: 3.767 ± 1.588
2.93GlyGly: 2.93 ± 1.235
1.674GlyHis: 1.674 ± 0.706
2.512GlyIle: 2.512 ± 0.973
2.093GlyLys: 2.093 ± 0.882
8.372GlyLeu: 8.372 ± 0.534
1.674GlyMet: 1.674 ± 1.252
0.837GlyAsn: 0.837 ± 0.353
2.512GlyPro: 2.512 ± 5.034
1.674GlyGln: 1.674 ± 0.706
2.093GlyArg: 2.093 ± 1.149
5.023GlySer: 5.023 ± 0.086
2.512GlyThr: 2.512 ± 1.058
4.604GlyVal: 4.604 ± 0.091
0.419GlyTrp: 0.419 ± 0.176
1.256GlyTyr: 1.256 ± 0.529
0.0GlyXaa: 0.0 ± 0.0
His
1.674HisAla: 1.674 ± 0.706
0.419HisCys: 0.419 ± 0.176
0.837HisAsp: 0.837 ± 0.353
1.256HisGlu: 1.256 ± 0.529
1.256HisPhe: 1.256 ± 1.502
1.674HisGly: 1.674 ± 1.325
0.837HisHis: 0.837 ± 1.678
2.093HisIle: 2.093 ± 0.882
1.674HisLys: 1.674 ± 0.706
3.349HisLeu: 3.349 ± 1.411
1.256HisMet: 1.256 ± 0.529
0.419HisAsn: 0.419 ± 0.176
2.512HisPro: 2.512 ± 1.058
0.419HisGln: 0.419 ± 0.176
2.093HisArg: 2.093 ± 0.882
2.093HisSer: 2.093 ± 0.882
0.419HisThr: 0.419 ± 0.176
2.93HisVal: 2.93 ± 0.796
0.837HisTrp: 0.837 ± 1.678
2.512HisTyr: 2.512 ± 1.058
0.0HisXaa: 0.0 ± 0.0
Ile
2.512IleAla: 2.512 ± 1.058
0.837IleCys: 0.837 ± 0.353
2.093IleAsp: 2.093 ± 1.149
2.093IleGlu: 2.093 ± 3.18
2.93IlePhe: 2.93 ± 2.827
4.604IleGly: 4.604 ± 1.94
1.674IleHis: 1.674 ± 0.706
2.512IleIle: 2.512 ± 1.058
2.93IleLys: 2.93 ± 1.235
5.023IleLeu: 5.023 ± 2.117
0.837IleMet: 0.837 ± 0.353
1.256IleAsn: 1.256 ± 0.529
6.697IlePro: 6.697 ± 1.239
2.512IleGln: 2.512 ± 1.058
5.023IleArg: 5.023 ± 0.086
2.512IleSer: 2.512 ± 1.058
5.442IleThr: 5.442 ± 0.262
2.93IleVal: 2.93 ± 1.235
0.0IleTrp: 0.0 ± 0.0
2.093IleTyr: 2.093 ± 1.149
0.0IleXaa: 0.0 ± 0.0
Lys
1.674LysAla: 1.674 ± 0.706
0.0LysCys: 0.0 ± 0.0
5.442LysAsp: 5.442 ± 2.293
2.512LysGlu: 2.512 ± 1.058
0.837LysPhe: 0.837 ± 0.353
4.186LysGly: 4.186 ± 1.764
0.837LysHis: 0.837 ± 0.353
4.186LysIle: 4.186 ± 1.764
2.512LysLys: 2.512 ± 1.058
4.604LysLeu: 4.604 ± 1.94
1.256LysMet: 1.256 ± 0.529
1.256LysAsn: 1.256 ± 0.529
0.837LysPro: 0.837 ± 0.353
0.419LysGln: 0.419 ± 0.176
3.767LysArg: 3.767 ± 1.588
5.023LysSer: 5.023 ± 2.117
2.512LysThr: 2.512 ± 1.058
2.93LysVal: 2.93 ± 1.235
1.256LysTrp: 1.256 ± 0.529
0.419LysTyr: 0.419 ± 0.176
0.0LysXaa: 0.0 ± 0.0
Leu
6.697LeuAla: 6.697 ± 0.791
0.837LeuCys: 0.837 ± 0.353
4.186LeuAsp: 4.186 ± 1.764
7.953LeuGlu: 7.953 ± 2.741
4.604LeuPhe: 4.604 ± 1.94
5.023LeuGly: 5.023 ± 2.117
2.093LeuHis: 2.093 ± 0.882
6.279LeuIle: 6.279 ± 2.646
6.697LeuLys: 6.697 ± 2.822
12.976LeuLeu: 12.976 ± 5.468
4.186LeuMet: 4.186 ± 0.267
5.86LeuAsn: 5.86 ± 3.623
4.604LeuPro: 4.604 ± 0.091
2.512LeuGln: 2.512 ± 0.973
8.372LeuArg: 8.372 ± 3.528
10.046LeuSer: 10.046 ± 2.203
9.627LeuThr: 9.627 ± 2.026
4.604LeuVal: 4.604 ± 0.091
0.419LeuTrp: 0.419 ± 0.176
2.512LeuTyr: 2.512 ± 0.973
0.0LeuXaa: 0.0 ± 0.0
Met
1.674MetAla: 1.674 ± 0.706
0.0MetCys: 0.0 ± 0.0
0.837MetAsp: 0.837 ± 0.353
1.256MetGlu: 1.256 ± 0.529
1.256MetPhe: 1.256 ± 1.502
1.674MetGly: 1.674 ± 0.706
0.0MetHis: 0.0 ± 0.0
1.674MetIle: 1.674 ± 0.706
0.0MetLys: 0.0 ± 0.0
1.674MetLeu: 1.674 ± 0.706
0.0MetMet: 0.0 ± 0.0
0.837MetAsn: 0.837 ± 0.353
1.256MetPro: 1.256 ± 0.529
0.419MetGln: 0.419 ± 0.176
0.837MetArg: 0.837 ± 0.353
1.674MetSer: 1.674 ± 1.325
3.349MetThr: 3.349 ± 0.62
2.512MetVal: 2.512 ± 1.058
1.256MetTrp: 1.256 ± 0.529
1.256MetTyr: 1.256 ± 0.529
0.0MetXaa: 0.0 ± 0.0
Asn
0.837AsnAla: 0.837 ± 1.678
0.419AsnCys: 0.419 ± 0.176
2.093AsnAsp: 2.093 ± 0.882
0.0AsnGlu: 0.0 ± 0.0
1.256AsnPhe: 1.256 ± 1.502
1.256AsnGly: 1.256 ± 0.529
0.837AsnHis: 0.837 ± 0.353
3.349AsnIle: 3.349 ± 1.411
2.093AsnLys: 2.093 ± 0.882
6.697AsnLeu: 6.697 ± 1.239
1.256AsnMet: 1.256 ± 0.529
1.256AsnAsn: 1.256 ± 0.529
3.349AsnPro: 3.349 ± 2.651
1.256AsnGln: 1.256 ± 0.529
0.0AsnArg: 0.0 ± 0.0
2.93AsnSer: 2.93 ± 1.235
0.837AsnThr: 0.837 ± 0.353
2.512AsnVal: 2.512 ± 0.973
1.256AsnTrp: 1.256 ± 0.529
0.837AsnTyr: 0.837 ± 0.353
0.0AsnXaa: 0.0 ± 0.0
Pro
2.512ProAla: 2.512 ± 5.034
0.0ProCys: 0.0 ± 0.0
2.93ProAsp: 2.93 ± 1.235
3.349ProGlu: 3.349 ± 1.411
1.256ProPhe: 1.256 ± 1.502
1.674ProGly: 1.674 ± 1.325
2.093ProHis: 2.093 ± 1.149
2.93ProIle: 2.93 ± 2.827
3.349ProLys: 3.349 ± 1.411
5.442ProLeu: 5.442 ± 2.293
2.512ProMet: 2.512 ± 1.058
2.512ProAsn: 2.512 ± 1.058
3.349ProPro: 3.349 ± 2.651
2.093ProGln: 2.093 ± 1.149
5.023ProArg: 5.023 ± 6.007
5.442ProSer: 5.442 ± 3.799
2.093ProThr: 2.093 ± 0.882
4.186ProVal: 4.186 ± 1.764
1.674ProTrp: 1.674 ± 1.325
1.674ProTyr: 1.674 ± 0.706
0.0ProXaa: 0.0 ± 0.0
Gln
0.837GlnAla: 0.837 ± 0.353
0.0GlnCys: 0.0 ± 0.0
1.256GlnAsp: 1.256 ± 0.529
2.93GlnGlu: 2.93 ± 2.827
2.093GlnPhe: 2.093 ± 1.149
1.674GlnGly: 1.674 ± 0.706
1.674GlnHis: 1.674 ± 1.325
1.674GlnIle: 1.674 ± 1.325
2.093GlnLys: 2.093 ± 0.882
3.349GlnLeu: 3.349 ± 1.411
1.256GlnMet: 1.256 ± 0.529
2.093GlnAsn: 2.093 ± 1.149
0.837GlnPro: 0.837 ± 0.353
1.256GlnGln: 1.256 ± 0.529
0.419GlnArg: 0.419 ± 0.176
3.349GlnSer: 3.349 ± 1.411
2.93GlnThr: 2.93 ± 2.827
2.93GlnVal: 2.93 ± 1.235
0.419GlnTrp: 0.419 ± 0.176
0.419GlnTyr: 0.419 ± 0.176
0.0GlnXaa: 0.0 ± 0.0
Arg
5.442ArgAla: 5.442 ± 3.799
4.186ArgCys: 4.186 ± 1.764
1.674ArgAsp: 1.674 ± 1.325
5.023ArgGlu: 5.023 ± 0.086
3.767ArgPhe: 3.767 ± 1.588
4.186ArgGly: 4.186 ± 0.267
2.093ArgHis: 2.093 ± 0.882
2.512ArgIle: 2.512 ± 1.058
2.512ArgLys: 2.512 ± 1.058
4.186ArgLeu: 4.186 ± 1.764
0.837ArgMet: 0.837 ± 0.353
3.767ArgAsn: 3.767 ± 0.443
3.767ArgPro: 3.767 ± 6.536
2.93ArgGln: 2.93 ± 0.796
3.767ArgArg: 3.767 ± 4.505
2.093ArgSer: 2.093 ± 3.18
3.349ArgThr: 3.349 ± 0.62
3.767ArgVal: 3.767 ± 0.443
2.512ArgTrp: 2.512 ± 0.973
0.837ArgTyr: 0.837 ± 0.353
0.0ArgXaa: 0.0 ± 0.0
Ser
7.116SerAla: 7.116 ± 3.094
0.0SerCys: 0.0 ± 0.0
3.767SerAsp: 3.767 ± 1.588
5.86SerGlu: 5.86 ± 0.439
6.279SerPhe: 6.279 ± 5.478
3.349SerGly: 3.349 ± 0.62
2.512SerHis: 2.512 ± 0.973
1.674SerIle: 1.674 ± 0.706
2.93SerLys: 2.93 ± 1.235
9.627SerLeu: 9.627 ± 2.026
0.419SerMet: 0.419 ± 0.176
2.512SerAsn: 2.512 ± 0.973
6.279SerPro: 6.279 ± 2.646
2.512SerGln: 2.512 ± 1.058
4.186SerArg: 4.186 ± 1.764
8.79SerSer: 8.79 ± 14.574
2.512SerThr: 2.512 ± 0.973
5.023SerVal: 5.023 ± 2.117
1.256SerTrp: 1.256 ± 0.529
3.767SerTyr: 3.767 ± 0.443
0.0SerXaa: 0.0 ± 0.0
Thr
2.512ThrAla: 2.512 ± 0.973
0.419ThrCys: 0.419 ± 0.176
1.674ThrAsp: 1.674 ± 0.706
4.604ThrGlu: 4.604 ± 1.94
2.093ThrPhe: 2.093 ± 0.882
4.604ThrGly: 4.604 ± 1.94
2.093ThrHis: 2.093 ± 0.882
4.186ThrIle: 4.186 ± 4.329
1.674ThrLys: 1.674 ± 0.706
7.535ThrLeu: 7.535 ± 4.948
1.256ThrMet: 1.256 ± 0.529
0.837ThrAsn: 0.837 ± 0.353
3.767ThrPro: 3.767 ± 2.474
1.674ThrGln: 1.674 ± 0.706
4.604ThrArg: 4.604 ± 1.94
5.86ThrSer: 5.86 ± 0.439
3.767ThrThr: 3.767 ± 1.588
5.442ThrVal: 5.442 ± 0.262
1.674ThrTrp: 1.674 ± 0.706
0.419ThrTyr: 0.419 ± 0.176
0.0ThrXaa: 0.0 ± 0.0
Val
5.023ValAla: 5.023 ± 0.086
1.256ValCys: 1.256 ± 0.529
3.767ValAsp: 3.767 ± 2.474
3.349ValGlu: 3.349 ± 1.411
3.767ValPhe: 3.767 ± 1.588
5.442ValGly: 5.442 ± 3.799
1.256ValHis: 1.256 ± 0.529
2.093ValIle: 2.093 ± 0.882
3.349ValLys: 3.349 ± 1.411
7.535ValLeu: 7.535 ± 3.175
2.093ValMet: 2.093 ± 0.882
1.674ValAsn: 1.674 ± 0.706
2.93ValPro: 2.93 ± 1.235
1.674ValGln: 1.674 ± 0.706
5.442ValArg: 5.442 ± 0.262
5.442ValSer: 5.442 ± 0.262
3.349ValThr: 3.349 ± 0.62
3.767ValVal: 3.767 ± 0.443
0.837ValTrp: 0.837 ± 0.353
0.837ValTyr: 0.837 ± 1.678
0.0ValXaa: 0.0 ± 0.0
Trp
0.419TrpAla: 0.419 ± 0.176
0.419TrpCys: 0.419 ± 0.176
1.674TrpAsp: 1.674 ± 0.706
3.349TrpGlu: 3.349 ± 0.62
1.674TrpPhe: 1.674 ± 0.706
1.256TrpGly: 1.256 ± 0.529
0.837TrpHis: 0.837 ± 0.353
1.674TrpIle: 1.674 ± 1.325
0.419TrpLys: 0.419 ± 0.176
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.256TrpAsn: 1.256 ± 0.529
0.837TrpPro: 0.837 ± 0.353
0.0TrpGln: 0.0 ± 0.0
1.256TrpArg: 1.256 ± 1.502
1.674TrpSer: 1.674 ± 0.706
1.674TrpThr: 1.674 ± 1.325
1.256TrpVal: 1.256 ± 0.529
0.0TrpTrp: 0.0 ± 0.0
0.419TrpTyr: 0.419 ± 0.176
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.674TyrAla: 1.674 ± 0.706
0.837TyrCys: 0.837 ± 0.353
1.674TyrAsp: 1.674 ± 1.325
2.093TyrGlu: 2.093 ± 0.882
1.256TyrPhe: 1.256 ± 0.529
1.256TyrGly: 1.256 ± 0.529
0.837TyrHis: 0.837 ± 0.353
1.674TyrIle: 1.674 ± 1.325
1.674TyrLys: 1.674 ± 0.706
2.93TyrLeu: 2.93 ± 0.796
0.0TyrMet: 0.0 ± 0.0
2.093TyrAsn: 2.093 ± 0.882
0.837TyrPro: 0.837 ± 0.353
2.093TyrGln: 2.093 ± 1.149
2.512TyrArg: 2.512 ± 3.003
2.512TyrSer: 2.512 ± 1.058
0.419TyrThr: 0.419 ± 0.176
1.256TyrVal: 1.256 ± 1.502
0.419TyrTrp: 0.419 ± 1.854
2.93TyrTyr: 2.93 ± 0.796
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2390 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski