Amino acid dipepetide frequency for Campylobacter blaseri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.162AlaAla: 3.162 ± 0.112
0.748AlaCys: 0.748 ± 0.044
2.502AlaAsp: 2.502 ± 0.076
2.324AlaGlu: 2.324 ± 0.075
3.047AlaPhe: 3.047 ± 0.085
3.852AlaGly: 3.852 ± 0.135
0.884AlaHis: 0.884 ± 0.047
6.155AlaIle: 6.155 ± 0.118
6.581AlaLys: 6.581 ± 0.126
6.324AlaLeu: 6.324 ± 0.117
1.794AlaMet: 1.794 ± 0.062
3.926AlaAsn: 3.926 ± 0.102
1.463AlaPro: 1.463 ± 0.059
1.488AlaGln: 1.488 ± 0.056
2.011AlaArg: 2.011 ± 0.075
3.748AlaSer: 3.748 ± 0.093
3.144AlaThr: 3.144 ± 0.071
3.368AlaVal: 3.368 ± 0.093
0.336AlaTrp: 0.336 ± 0.023
2.33AlaTyr: 2.33 ± 0.072
0.0AlaXaa: 0.0 ± 0.0
Cys
0.584CysAla: 0.584 ± 0.034
0.111CysCys: 0.111 ± 0.015
0.721CysAsp: 0.721 ± 0.039
0.802CysGlu: 0.802 ± 0.045
0.552CysPhe: 0.552 ± 0.033
0.953CysGly: 0.953 ± 0.05
0.255CysHis: 0.255 ± 0.033
0.827CysIle: 0.827 ± 0.044
0.906CysLys: 0.906 ± 0.04
0.753CysLeu: 0.753 ± 0.045
0.217CysMet: 0.217 ± 0.019
0.469CysAsn: 0.469 ± 0.038
0.374CysPro: 0.374 ± 0.028
0.196CysGln: 0.196 ± 0.021
0.228CysArg: 0.228 ± 0.021
0.717CysSer: 0.717 ± 0.039
0.377CysThr: 0.377 ± 0.027
0.627CysVal: 0.627 ± 0.037
0.079CysTrp: 0.079 ± 0.015
0.403CysTyr: 0.403 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
2.772AspAla: 2.772 ± 0.07
0.527AspCys: 0.527 ± 0.032
3.462AspAsp: 3.462 ± 0.119
5.747AspGlu: 5.747 ± 0.099
3.354AspPhe: 3.354 ± 0.091
3.687AspGly: 3.687 ± 0.106
0.527AspHis: 0.527 ± 0.031
6.584AspIle: 6.584 ± 0.119
6.104AspLys: 6.104 ± 0.116
4.905AspLeu: 4.905 ± 0.111
1.431AspMet: 1.431 ± 0.05
3.343AspAsn: 3.343 ± 0.095
1.359AspPro: 1.359 ± 0.05
0.735AspGln: 0.735 ± 0.039
2.033AspArg: 2.033 ± 0.069
3.602AspSer: 3.602 ± 0.093
2.556AspThr: 2.556 ± 0.101
3.286AspVal: 3.286 ± 0.081
0.331AspTrp: 0.331 ± 0.023
2.398AspTyr: 2.398 ± 0.066
0.0AspXaa: 0.0 ± 0.0
Glu
3.751GluAla: 3.751 ± 0.089
0.622GluCys: 0.622 ± 0.034
3.769GluAsp: 3.769 ± 0.103
4.537GluGlu: 4.537 ± 0.122
4.026GluPhe: 4.026 ± 0.11
2.723GluGly: 2.723 ± 0.078
1.05GluHis: 1.05 ± 0.05
7.636GluIle: 7.636 ± 0.13
7.253GluLys: 7.253 ± 0.128
7.073GluLeu: 7.073 ± 0.127
1.46GluMet: 1.46 ± 0.055
5.236GluAsn: 5.236 ± 0.092
1.495GluPro: 1.495 ± 0.057
1.851GluGln: 1.851 ± 0.066
1.927GluArg: 1.927 ± 0.066
2.968GluSer: 2.968 ± 0.071
2.277GluThr: 2.277 ± 0.069
3.759GluVal: 3.759 ± 0.086
0.505GluTrp: 0.505 ± 0.03
2.851GluTyr: 2.851 ± 0.071
0.0GluXaa: 0.0 ± 0.0
Phe
3.25PheAla: 3.25 ± 0.089
0.696PheCys: 0.696 ± 0.036
3.572PheAsp: 3.572 ± 0.083
3.631PheGlu: 3.631 ± 0.08
3.27PhePhe: 3.27 ± 0.11
3.832PheGly: 3.832 ± 0.094
0.652PheHis: 0.652 ± 0.04
5.365PheIle: 5.365 ± 0.12
5.044PheLys: 5.044 ± 0.108
5.788PheLeu: 5.788 ± 0.15
1.269PheMet: 1.269 ± 0.048
3.361PheAsn: 3.361 ± 0.101
1.057PhePro: 1.057 ± 0.05
0.958PheGln: 0.958 ± 0.046
1.416PheArg: 1.416 ± 0.054
4.336PheSer: 4.336 ± 0.101
2.518PheThr: 2.518 ± 0.064
3.155PheVal: 3.155 ± 0.101
0.464PheTrp: 0.464 ± 0.029
2.472PheTyr: 2.472 ± 0.079
0.0PheXaa: 0.0 ± 0.0
Gly
3.999GlyAla: 3.999 ± 0.119
0.755GlyCys: 0.755 ± 0.046
3.342GlyAsp: 3.342 ± 0.1
3.568GlyGlu: 3.568 ± 0.088
3.606GlyPhe: 3.606 ± 0.088
4.433GlyGly: 4.433 ± 0.151
0.945GlyHis: 0.945 ± 0.045
5.738GlyIle: 5.738 ± 0.11
5.218GlyLys: 5.218 ± 0.119
5.27GlyLeu: 5.27 ± 0.105
1.522GlyMet: 1.522 ± 0.063
2.944GlyAsn: 2.944 ± 0.128
0.875GlyPro: 0.875 ± 0.043
1.177GlyGln: 1.177 ± 0.058
1.842GlyArg: 1.842 ± 0.067
3.854GlySer: 3.854 ± 0.101
2.518GlyThr: 2.518 ± 0.085
4.515GlyVal: 4.515 ± 0.107
0.44GlyTrp: 0.44 ± 0.032
2.791GlyTyr: 2.791 ± 0.081
0.0GlyXaa: 0.0 ± 0.0
His
0.782HisAla: 0.782 ± 0.039
0.18HisCys: 0.18 ± 0.018
0.62HisAsp: 0.62 ± 0.036
0.773HisGlu: 0.773 ± 0.044
0.816HisPhe: 0.816 ± 0.039
0.854HisGly: 0.854 ± 0.039
0.295HisHis: 0.295 ± 0.027
1.433HisIle: 1.433 ± 0.05
1.282HisLys: 1.282 ± 0.05
1.359HisLeu: 1.359 ± 0.057
0.343HisMet: 0.343 ± 0.024
0.8HisAsn: 0.8 ± 0.036
0.618HisPro: 0.618 ± 0.034
0.388HisGln: 0.388 ± 0.025
0.471HisArg: 0.471 ± 0.031
1.053HisSer: 1.053 ± 0.038
0.73HisThr: 0.73 ± 0.037
0.534HisVal: 0.534 ± 0.033
0.111HisTrp: 0.111 ± 0.015
0.654HisTyr: 0.654 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
6.05IleAla: 6.05 ± 0.118
1.129IleCys: 1.129 ± 0.049
5.973IleAsp: 5.973 ± 0.11
6.124IleGlu: 6.124 ± 0.119
5.463IlePhe: 5.463 ± 0.137
5.628IleGly: 5.628 ± 0.121
1.188IleHis: 1.188 ± 0.052
8.213IleIle: 8.213 ± 0.149
9.545IleLys: 9.545 ± 0.153
9.715IleLeu: 9.715 ± 0.155
1.956IleMet: 1.956 ± 0.062
6.12IleAsn: 6.12 ± 0.148
2.766IlePro: 2.766 ± 0.075
1.869IleGln: 1.869 ± 0.058
2.538IleArg: 2.538 ± 0.066
7.289IleSer: 7.289 ± 0.12
4.404IleThr: 4.404 ± 0.091
5.72IleVal: 5.72 ± 0.106
0.572IleTrp: 0.572 ± 0.032
3.956IleTyr: 3.956 ± 0.094
0.0IleXaa: 0.0 ± 0.0
Lys
5.507LysAla: 5.507 ± 0.104
0.712LysCys: 0.712 ± 0.046
7.81LysAsp: 7.81 ± 0.146
8.766LysGlu: 8.766 ± 0.16
5.391LysPhe: 5.391 ± 0.123
4.508LysGly: 4.508 ± 0.092
1.176LysHis: 1.176 ± 0.049
9.548LysIle: 9.548 ± 0.126
9.956LysLys: 9.956 ± 0.197
7.415LysLeu: 7.415 ± 0.126
2.356LysMet: 2.356 ± 0.063
8.538LysAsn: 8.538 ± 0.14
2.414LysPro: 2.414 ± 0.08
2.531LysGln: 2.531 ± 0.074
3.138LysArg: 3.138 ± 0.076
5.675LysSer: 5.675 ± 0.111
5.024LysThr: 5.024 ± 0.097
4.744LysVal: 4.744 ± 0.102
0.552LysTrp: 0.552 ± 0.037
3.992LysTyr: 3.992 ± 0.094
0.0LysXaa: 0.0 ± 0.0
Leu
6.174LeuAla: 6.174 ± 0.116
0.974LeuCys: 0.974 ± 0.038
5.516LeuAsp: 5.516 ± 0.103
6.485LeuGlu: 6.485 ± 0.127
4.986LeuPhe: 4.986 ± 0.11
5.628LeuGly: 5.628 ± 0.102
1.21LeuHis: 1.21 ± 0.049
7.934LeuIle: 7.934 ± 0.148
10.283LeuLys: 10.283 ± 0.165
7.814LeuLeu: 7.814 ± 0.144
2.126LeuMet: 2.126 ± 0.06
7.008LeuAsn: 7.008 ± 0.146
2.966LeuPro: 2.966 ± 0.068
2.211LeuGln: 2.211 ± 0.067
2.869LeuArg: 2.869 ± 0.071
7.211LeuSer: 7.211 ± 0.14
4.422LeuThr: 4.422 ± 0.092
5.116LeuVal: 5.116 ± 0.104
0.582LeuTrp: 0.582 ± 0.04
3.284LeuTyr: 3.284 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.582MetAla: 1.582 ± 0.062
0.2MetCys: 0.2 ± 0.018
1.246MetAsp: 1.246 ± 0.047
1.321MetGlu: 1.321 ± 0.05
1.15MetPhe: 1.15 ± 0.051
1.576MetGly: 1.576 ± 0.058
0.399MetHis: 0.399 ± 0.027
1.999MetIle: 1.999 ± 0.063
2.243MetLys: 2.243 ± 0.06
2.401MetLeu: 2.401 ± 0.065
0.595MetMet: 0.595 ± 0.036
1.201MetAsn: 1.201 ± 0.047
0.954MetPro: 0.954 ± 0.042
0.931MetGln: 0.931 ± 0.04
0.791MetArg: 0.791 ± 0.038
1.636MetSer: 1.636 ± 0.055
0.861MetThr: 0.861 ± 0.037
1.388MetVal: 1.388 ± 0.049
0.138MetTrp: 0.138 ± 0.015
0.606MetTyr: 0.606 ± 0.036
0.0MetXaa: 0.0 ± 0.0
Asn
3.545AsnAla: 3.545 ± 0.09
0.53AsnCys: 0.53 ± 0.035
3.386AsnAsp: 3.386 ± 0.114
4.74AsnGlu: 4.74 ± 0.101
3.821AsnPhe: 3.821 ± 0.09
3.64AsnGly: 3.64 ± 0.107
0.875AsnHis: 0.875 ± 0.038
6.936AsnIle: 6.936 ± 0.162
5.854AsnLys: 5.854 ± 0.117
7.619AsnLeu: 7.619 ± 0.154
1.22AsnMet: 1.22 ± 0.046
3.676AsnAsn: 3.676 ± 0.122
2.159AsnPro: 2.159 ± 0.072
1.593AsnGln: 1.593 ± 0.054
1.887AsnArg: 1.887 ± 0.063
4.99AsnSer: 4.99 ± 0.132
2.842AsnThr: 2.842 ± 0.078
2.982AsnVal: 2.982 ± 0.088
0.359AsnTrp: 0.359 ± 0.026
2.757AsnTyr: 2.757 ± 0.069
0.0AsnXaa: 0.0 ± 0.0
Pro
1.389ProAla: 1.389 ± 0.06
0.259ProCys: 0.259 ± 0.023
1.292ProAsp: 1.292 ± 0.05
1.551ProGlu: 1.551 ± 0.059
1.655ProPhe: 1.655 ± 0.055
1.247ProGly: 1.247 ± 0.052
0.489ProHis: 0.489 ± 0.027
2.498ProIle: 2.498 ± 0.084
2.804ProLys: 2.804 ± 0.078
2.585ProLeu: 2.585 ± 0.07
0.678ProMet: 0.678 ± 0.038
1.952ProAsn: 1.952 ± 0.063
0.67ProPro: 0.67 ± 0.031
0.687ProGln: 0.687 ± 0.037
0.791ProArg: 0.791 ± 0.033
1.735ProSer: 1.735 ± 0.064
1.454ProThr: 1.454 ± 0.052
1.603ProVal: 1.603 ± 0.06
0.226ProTrp: 0.226 ± 0.019
1.213ProTyr: 1.213 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
1.397GlnAla: 1.397 ± 0.054
0.171GlnCys: 0.171 ± 0.018
1.388GlnAsp: 1.388 ± 0.045
1.591GlnGlu: 1.591 ± 0.067
0.911GlnPhe: 0.911 ± 0.042
1.235GlnGly: 1.235 ± 0.048
0.295GlnHis: 0.295 ± 0.024
2.662GlnIle: 2.662 ± 0.072
2.791GlnLys: 2.791 ± 0.079
1.472GlnLeu: 1.472 ± 0.053
0.586GlnMet: 0.586 ± 0.033
2.216GlnAsn: 2.216 ± 0.067
0.505GlnPro: 0.505 ± 0.031
0.464GlnGln: 0.464 ± 0.029
0.859GlnArg: 0.859 ± 0.043
1.47GlnSer: 1.47 ± 0.057
1.353GlnThr: 1.353 ± 0.052
1.089GlnVal: 1.089 ± 0.048
0.149GlnTrp: 0.149 ± 0.013
0.717GlnTyr: 0.717 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.139ArgAla: 2.139 ± 0.072
0.291ArgCys: 0.291 ± 0.023
1.972ArgAsp: 1.972 ± 0.067
2.099ArgGlu: 2.099 ± 0.065
1.704ArgPhe: 1.704 ± 0.058
1.715ArgGly: 1.715 ± 0.061
0.543ArgHis: 0.543 ± 0.033
2.457ArgIle: 2.457 ± 0.069
2.518ArgLys: 2.518 ± 0.073
2.955ArgLeu: 2.955 ± 0.073
0.746ArgMet: 0.746 ± 0.038
1.722ArgAsn: 1.722 ± 0.059
0.766ArgPro: 0.766 ± 0.041
0.847ArgGln: 0.847 ± 0.038
1.183ArgArg: 1.183 ± 0.056
1.695ArgSer: 1.695 ± 0.054
1.262ArgThr: 1.262 ± 0.045
2.331ArgVal: 2.331 ± 0.076
0.223ArgTrp: 0.223 ± 0.023
1.478ArgTyr: 1.478 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
3.703SerAla: 3.703 ± 0.09
0.688SerCys: 0.688 ± 0.048
3.482SerAsp: 3.482 ± 0.086
3.629SerGlu: 3.629 ± 0.09
4.152SerPhe: 4.152 ± 0.101
4.379SerGly: 4.379 ± 0.11
0.927SerHis: 0.927 ± 0.048
6.153SerIle: 6.153 ± 0.118
7.034SerLys: 7.034 ± 0.13
6.491SerLeu: 6.491 ± 0.126
1.517SerMet: 1.517 ± 0.051
4.147SerAsn: 4.147 ± 0.121
1.614SerPro: 1.614 ± 0.055
1.664SerGln: 1.664 ± 0.056
2.071SerArg: 2.071 ± 0.065
5.071SerSer: 5.071 ± 0.108
2.79SerThr: 2.79 ± 0.078
3.94SerVal: 3.94 ± 0.088
0.516SerTrp: 0.516 ± 0.033
2.881SerTyr: 2.881 ± 0.074
0.0SerXaa: 0.0 ± 0.0
Thr
2.685ThrAla: 2.685 ± 0.07
0.399ThrCys: 0.399 ± 0.032
2.216ThrAsp: 2.216 ± 0.076
1.792ThrGlu: 1.792 ± 0.056
2.24ThrPhe: 2.24 ± 0.065
2.748ThrGly: 2.748 ± 0.084
0.874ThrHis: 0.874 ± 0.04
4.769ThrIle: 4.769 ± 0.132
4.652ThrLys: 4.652 ± 0.092
4.862ThrLeu: 4.862 ± 0.089
1.017ThrMet: 1.017 ± 0.041
3.023ThrAsn: 3.023 ± 0.078
1.927ThrPro: 1.927 ± 0.06
1.352ThrGln: 1.352 ± 0.048
1.438ThrArg: 1.438 ± 0.055
2.971ThrSer: 2.971 ± 0.069
2.678ThrThr: 2.678 ± 0.076
1.846ThrVal: 1.846 ± 0.06
0.316ThrTrp: 0.316 ± 0.025
1.614ThrTyr: 1.614 ± 0.061
0.0ThrXaa: 0.0 ± 0.0
Val
3.89ValAla: 3.89 ± 0.095
0.712ValCys: 0.712 ± 0.037
3.475ValAsp: 3.475 ± 0.092
3.773ValGlu: 3.773 ± 0.084
3.237ValPhe: 3.237 ± 0.099
3.877ValGly: 3.877 ± 0.101
0.726ValHis: 0.726 ± 0.038
4.948ValIle: 4.948 ± 0.102
5.065ValLys: 5.065 ± 0.114
5.482ValLeu: 5.482 ± 0.098
1.305ValMet: 1.305 ± 0.051
3.002ValAsn: 3.002 ± 0.074
1.469ValPro: 1.469 ± 0.059
1.089ValGln: 1.089 ± 0.05
1.654ValArg: 1.654 ± 0.056
3.791ValSer: 3.791 ± 0.081
2.195ValThr: 2.195 ± 0.08
4.062ValVal: 4.062 ± 0.1
0.403ValTrp: 0.403 ± 0.031
2.037ValTyr: 2.037 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
0.491TrpAla: 0.491 ± 0.031
0.088TrpCys: 0.088 ± 0.014
0.433TrpAsp: 0.433 ± 0.028
0.368TrpGlu: 0.368 ± 0.026
0.381TrpPhe: 0.381 ± 0.028
0.503TrpGly: 0.503 ± 0.034
0.144TrpHis: 0.144 ± 0.014
0.624TrpIle: 0.624 ± 0.042
0.426TrpLys: 0.426 ± 0.027
0.703TrpLeu: 0.703 ± 0.036
0.205TrpMet: 0.205 ± 0.02
0.315TrpAsn: 0.315 ± 0.026
0.111TrpPro: 0.111 ± 0.014
0.275TrpGln: 0.275 ± 0.022
0.187TrpArg: 0.187 ± 0.02
0.367TrpSer: 0.367 ± 0.028
0.237TrpThr: 0.237 ± 0.022
0.388TrpVal: 0.388 ± 0.024
0.11TrpTrp: 0.11 ± 0.013
0.298TrpTyr: 0.298 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.333TyrAla: 2.333 ± 0.065
0.361TyrCys: 0.361 ± 0.024
2.565TyrAsp: 2.565 ± 0.074
3.147TyrGlu: 3.147 ± 0.081
2.342TyrPhe: 2.342 ± 0.069
2.337TyrGly: 2.337 ± 0.078
0.642TyrHis: 0.642 ± 0.033
3.739TyrIle: 3.739 ± 0.105
4.195TyrLys: 4.195 ± 0.104
3.814TyrLeu: 3.814 ± 0.093
0.872TyrMet: 0.872 ± 0.036
2.414TyrAsn: 2.414 ± 0.071
1.217TyrPro: 1.217 ± 0.05
1.016TyrGln: 1.016 ± 0.04
1.31TyrArg: 1.31 ± 0.041
2.671TyrSer: 2.671 ± 0.065
1.778TyrThr: 1.778 ± 0.06
1.738TyrVal: 1.738 ± 0.061
0.241TyrTrp: 0.241 ± 0.021
1.602TyrTyr: 1.602 ± 0.061
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1788 proteins (556337 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski