Amino acid dipepetide frequency for Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.758AlaAla: 6.758 ± 0.105	0.86AlaCys: 0.86 ± 0.026	4.077AlaAsp: 4.077 ± 0.068	5.209AlaGlu: 5.209 ± 0.074	3.32AlaPhe: 3.32 ± 0.057	5.248AlaGly: 5.248 ± 0.076	1.499AlaHis: 1.499 ± 0.033	6.107AlaIle: 6.107 ± 0.089	4.834AlaLys: 4.834 ± 0.065	8.946AlaLeu: 8.946 ± 0.092	2.472AlaMet: 2.472 ± 0.05	3.397AlaAsn: 3.397 ± 0.058	2.693AlaPro: 2.693 ± 0.056	3.41AlaGln: 3.41 ± 0.057	3.007AlaArg: 3.007 ± 0.055	5.03AlaSer: 5.03 ± 0.072	4.305AlaThr: 4.305 ± 0.059	5.348AlaVal: 5.348 ± 0.075	0.908AlaTrp: 0.908 ± 0.034	2.32AlaTyr: 2.32 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.716CysAla: 0.716 ± 0.025	0.158CysCys: 0.158 ± 0.011	0.616CysAsp: 0.616 ± 0.021	0.642CysGlu: 0.642 ± 0.027	0.48CysPhe: 0.48 ± 0.021	0.842CysGly: 0.842 ± 0.028	0.328CysHis: 0.328 ± 0.018	0.682CysIle: 0.682 ± 0.026	0.496CysLys: 0.496 ± 0.023	0.916CysLeu: 0.916 ± 0.026	0.237CysMet: 0.237 ± 0.016	0.397CysAsn: 0.397 ± 0.017	0.424CysPro: 0.424 ± 0.024	0.435CysGln: 0.435 ± 0.02	0.399CysArg: 0.399 ± 0.019	0.766CysSer: 0.766 ± 0.022	0.483CysThr: 0.483 ± 0.023	0.654CysVal: 0.654 ± 0.025	0.133CysTrp: 0.133 ± 0.01	0.335CysTyr: 0.335 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.219AspAla: 4.219 ± 0.064	0.509AspCys: 0.509 ± 0.021	3.136AspAsp: 3.136 ± 0.068	4.038AspGlu: 4.038 ± 0.072	2.502AspPhe: 2.502 ± 0.047	3.613AspGly: 3.613 ± 0.082	1.083AspHis: 1.083 ± 0.03	4.423AspIle: 4.423 ± 0.072	3.523AspLys: 3.523 ± 0.052	5.247AspLeu: 5.247 ± 0.066	1.459AspMet: 1.459 ± 0.035	2.711AspAsn: 2.711 ± 0.056	1.853AspPro: 1.853 ± 0.048	1.728AspGln: 1.728 ± 0.038	2.014AspArg: 2.014 ± 0.046	3.396AspSer: 3.396 ± 0.059	2.682AspThr: 2.682 ± 0.073	3.907AspVal: 3.907 ± 0.063	0.812AspTrp: 0.812 ± 0.025	2.001AspTyr: 2.001 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	5.199GluAla: 5.199 ± 0.082	0.583GluCys: 0.583 ± 0.022	3.017GluAsp: 3.017 ± 0.074	4.536GluGlu: 4.536 ± 0.08	2.599GluPhe: 2.599 ± 0.046	3.656GluGly: 3.656 ± 0.055	1.603GluHis: 1.603 ± 0.043	4.225GluIle: 4.225 ± 0.076	4.52GluLys: 4.52 ± 0.073	7.453GluLeu: 7.453 ± 0.087	1.897GluMet: 1.897 ± 0.039	3.085GluAsn: 3.085 ± 0.048	2.015GluPro: 2.015 ± 0.044	3.731GluGln: 3.731 ± 0.06	3.13GluArg: 3.13 ± 0.058	3.942GluSer: 3.942 ± 0.071	3.351GluThr: 3.351 ± 0.062	4.351GluVal: 4.351 ± 0.074	0.847GluTrp: 0.847 ± 0.028	1.983GluTyr: 1.983 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	3.412PheAla: 3.412 ± 0.061	0.542PheCys: 0.542 ± 0.023	2.747PheAsp: 2.747 ± 0.046	2.528PheGlu: 2.528 ± 0.052	1.892PhePhe: 1.892 ± 0.047	3.127PheGly: 3.127 ± 0.051	0.868PheHis: 0.868 ± 0.03	3.246PheIle: 3.246 ± 0.061	2.265PheLys: 2.265 ± 0.043	3.591PheLeu: 3.591 ± 0.07	1.077PheMet: 1.077 ± 0.027	2.24PheAsn: 2.24 ± 0.045	1.418PhePro: 1.418 ± 0.035	1.262PheGln: 1.262 ± 0.033	1.37PheArg: 1.37 ± 0.035	3.578PheSer: 3.578 ± 0.066	2.584PheThr: 2.584 ± 0.051	2.831PheVal: 2.831 ± 0.056	0.505PheTrp: 0.505 ± 0.024	1.41PheTyr: 1.41 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.824GlyAla: 4.824 ± 0.08	0.879GlyCys: 0.879 ± 0.03	3.533GlyAsp: 3.533 ± 0.069	4.157GlyGlu: 4.157 ± 0.063	3.288GlyPhe: 3.288 ± 0.049	4.495GlyGly: 4.495 ± 0.081	1.45GlyHis: 1.45 ± 0.04	4.869GlyIle: 4.869 ± 0.07	3.997GlyLys: 3.997 ± 0.059	6.747GlyLeu: 6.747 ± 0.084	2.042GlyMet: 2.042 ± 0.045	2.766GlyAsn: 2.766 ± 0.068	1.543GlyPro: 1.543 ± 0.038	2.444GlyGln: 2.444 ± 0.051	2.7GlyArg: 2.7 ± 0.054	4.09GlySer: 4.09 ± 0.076	3.369GlyThr: 3.369 ± 0.066	4.786GlyVal: 4.786 ± 0.07	0.897GlyTrp: 0.897 ± 0.026	2.567GlyTyr: 2.567 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.498HisAla: 1.498 ± 0.037	0.317HisCys: 0.317 ± 0.016	1.092HisAsp: 1.092 ± 0.035	1.117HisGlu: 1.117 ± 0.029	1.098HisPhe: 1.098 ± 0.031	1.379HisGly: 1.379 ± 0.033	0.697HisHis: 0.697 ± 0.028	1.535HisIle: 1.535 ± 0.035	1.152HisLys: 1.152 ± 0.03	2.182HisLeu: 2.182 ± 0.044	0.486HisMet: 0.486 ± 0.017	1.008HisAsn: 1.008 ± 0.029	1.03HisPro: 1.03 ± 0.033	1.14HisGln: 1.14 ± 0.036	0.932HisArg: 0.932 ± 0.031	1.439HisSer: 1.439 ± 0.035	1.109HisThr: 1.109 ± 0.029	1.222HisVal: 1.222 ± 0.035	0.342HisTrp: 0.342 ± 0.017	0.86HisTyr: 0.86 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.383IleAla: 6.383 ± 0.078	0.727IleCys: 0.727 ± 0.028	4.461IleAsp: 4.461 ± 0.067	5.224IleGlu: 5.224 ± 0.068	2.541IlePhe: 2.541 ± 0.053	4.964IleGly: 4.964 ± 0.068	1.369IleHis: 1.369 ± 0.035	4.62IleIle: 4.62 ± 0.075	4.143IleLys: 4.143 ± 0.059	5.835IleLeu: 5.835 ± 0.076	1.514IleMet: 1.514 ± 0.036	3.767IleAsn: 3.767 ± 0.057	2.757IlePro: 2.757 ± 0.049	2.587IleGln: 2.587 ± 0.049	2.709IleArg: 2.709 ± 0.05	5.389IleSer: 5.389 ± 0.074	4.47IleThr: 4.47 ± 0.079	4.305IleVal: 4.305 ± 0.07	0.627IleTrp: 0.627 ± 0.022	1.967IleTyr: 1.967 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	5.037LysAla: 5.037 ± 0.069	0.354LysCys: 0.354 ± 0.02	3.064LysAsp: 3.064 ± 0.052	4.693LysGlu: 4.693 ± 0.064	1.796LysPhe: 1.796 ± 0.037	3.694LysGly: 3.694 ± 0.063	1.303LysHis: 1.303 ± 0.035	3.529LysIle: 3.529 ± 0.062	4.003LysLys: 4.003 ± 0.073	5.582LysLeu: 5.582 ± 0.078	1.729LysMet: 1.729 ± 0.039	2.909LysAsn: 2.909 ± 0.056	2.387LysPro: 2.387 ± 0.047	3.011LysGln: 3.011 ± 0.056	2.64LysArg: 2.64 ± 0.045	3.442LysSer: 3.442 ± 0.054	3.254LysThr: 3.254 ± 0.06	4.015LysVal: 4.015 ± 0.066	0.627LysTrp: 0.627 ± 0.026	1.748LysTyr: 1.748 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	8.788LeuAla: 8.788 ± 0.106	1.037LeuCys: 1.037 ± 0.034	5.77LeuAsp: 5.77 ± 0.083	6.145LeuGlu: 6.145 ± 0.082	4.562LeuPhe: 4.562 ± 0.076	6.551LeuGly: 6.551 ± 0.081	1.965LeuHis: 1.965 ± 0.047	7.015LeuIle: 7.015 ± 0.091	5.466LeuLys: 5.466 ± 0.079	10.516LeuLeu: 10.516 ± 0.129	2.696LeuMet: 2.696 ± 0.047	5.113LeuAsn: 5.113 ± 0.077	4.604LeuPro: 4.604 ± 0.054	3.425LeuGln: 3.425 ± 0.059	3.891LeuArg: 3.891 ± 0.068	8.236LeuSer: 8.236 ± 0.091	6.186LeuThr: 6.186 ± 0.083	6.47LeuVal: 6.47 ± 0.094	0.977LeuTrp: 0.977 ± 0.03	2.599LeuTyr: 2.599 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.437MetAla: 2.437 ± 0.047	0.23MetCys: 0.23 ± 0.014	1.352MetAsp: 1.352 ± 0.035	1.356MetGlu: 1.356 ± 0.039	1.013MetPhe: 1.013 ± 0.031	1.794MetGly: 1.794 ± 0.043	0.479MetHis: 0.479 ± 0.018	1.76MetIle: 1.76 ± 0.038	1.836MetLys: 1.836 ± 0.04	2.642MetLeu: 2.642 ± 0.05	0.918MetMet: 0.918 ± 0.029	1.404MetAsn: 1.404 ± 0.033	1.195MetPro: 1.195 ± 0.031	1.023MetGln: 1.023 ± 0.029	1.129MetArg: 1.129 ± 0.029	2.029MetSer: 2.029 ± 0.041	1.657MetThr: 1.657 ± 0.036	1.857MetVal: 1.857 ± 0.043	0.227MetTrp: 0.227 ± 0.014	0.636MetTyr: 0.636 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.545AsnAla: 3.545 ± 0.057	0.413AsnCys: 0.413 ± 0.018	2.746AsnAsp: 2.746 ± 0.061	3.005AsnGlu: 3.005 ± 0.056	1.712AsnPhe: 1.712 ± 0.035	3.244AsnGly: 3.244 ± 0.056	1.097AsnHis: 1.097 ± 0.031	3.398AsnIle: 3.398 ± 0.058	3.131AsnLys: 3.131 ± 0.05	4.205AsnLeu: 4.205 ± 0.058	1.166AsnMet: 1.166 ± 0.035	2.531AsnAsn: 2.531 ± 0.052	2.1AsnPro: 2.1 ± 0.044	2.336AsnGln: 2.336 ± 0.045	2.001AsnArg: 2.001 ± 0.046	2.893AsnSer: 2.893 ± 0.058	2.629AsnThr: 2.629 ± 0.054	3.047AsnVal: 3.047 ± 0.047	0.595AsnTrp: 0.595 ± 0.026	1.612AsnTyr: 1.612 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.517ProAla: 2.517 ± 0.051	0.289ProCys: 0.289 ± 0.015	2.016ProAsp: 2.016 ± 0.041	3.131ProGlu: 3.131 ± 0.06	1.68ProPhe: 1.68 ± 0.033	1.848ProGly: 1.848 ± 0.046	0.827ProHis: 0.827 ± 0.024	2.701ProIle: 2.701 ± 0.053	2.23ProLys: 2.23 ± 0.042	3.906ProLeu: 3.906 ± 0.063	1.039ProMet: 1.039 ± 0.031	1.799ProAsn: 1.799 ± 0.048	0.965ProPro: 0.965 ± 0.031	1.527ProGln: 1.527 ± 0.034	1.151ProArg: 1.151 ± 0.029	2.559ProSer: 2.559 ± 0.049	2.299ProThr: 2.299 ± 0.048	2.81ProVal: 2.81 ± 0.054	0.459ProTrp: 0.459 ± 0.02	1.235ProTyr: 1.235 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.618GlnAla: 3.618 ± 0.06	0.412GlnCys: 0.412 ± 0.018	1.998GlnAsp: 1.998 ± 0.041	2.64GlnGlu: 2.64 ± 0.045	1.776GlnPhe: 1.776 ± 0.04	2.595GlnGly: 2.595 ± 0.044	1.056GlnHis: 1.056 ± 0.032	2.589GlnIle: 2.589 ± 0.047	2.298GlnLys: 2.298 ± 0.05	4.945GlnLeu: 4.945 ± 0.072	1.022GlnMet: 1.022 ± 0.027	1.722GlnAsn: 1.722 ± 0.038	1.521GlnPro: 1.521 ± 0.035	2.554GlnGln: 2.554 ± 0.061	1.971GlnArg: 1.971 ± 0.04	2.671GlnSer: 2.671 ± 0.049	2.16GlnThr: 2.16 ± 0.039	2.88GlnVal: 2.88 ± 0.058	0.603GlnTrp: 0.603 ± 0.02	1.51GlnTyr: 1.51 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.827ArgAla: 2.827 ± 0.051	0.421ArgCys: 0.421 ± 0.02	2.177ArgAsp: 2.177 ± 0.05	2.668ArgGlu: 2.668 ± 0.049	2.05ArgPhe: 2.05 ± 0.043	2.294ArgGly: 2.294 ± 0.048	0.948ArgHis: 0.948 ± 0.033	2.907ArgIle: 2.907 ± 0.056	2.34ArgLys: 2.34 ± 0.048	4.406ArgLeu: 4.406 ± 0.065	1.13ArgMet: 1.13 ± 0.034	1.902ArgAsn: 1.902 ± 0.039	1.347ArgPro: 1.347 ± 0.034	1.7ArgGln: 1.7 ± 0.048	1.954ArgArg: 1.954 ± 0.057	2.464ArgSer: 2.464 ± 0.042	2.106ArgThr: 2.106 ± 0.04	2.704ArgVal: 2.704 ± 0.053	0.523ArgTrp: 0.523 ± 0.022	1.514ArgTyr: 1.514 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.002SerAla: 5.002 ± 0.071	0.644SerCys: 0.644 ± 0.025	3.835SerAsp: 3.835 ± 0.06	4.432SerGlu: 4.432 ± 0.068	3.072SerPhe: 3.072 ± 0.049	4.836SerGly: 4.836 ± 0.062	1.54SerHis: 1.54 ± 0.038	5.047SerIle: 5.047 ± 0.07	3.676SerLys: 3.676 ± 0.06	7.177SerLeu: 7.177 ± 0.096	1.902SerMet: 1.902 ± 0.04	3.124SerAsn: 3.124 ± 0.063	2.301SerPro: 2.301 ± 0.048	2.934SerGln: 2.934 ± 0.053	2.555SerArg: 2.555 ± 0.053	4.808SerSer: 4.808 ± 0.072	3.629SerThr: 3.629 ± 0.072	4.64SerVal: 4.64 ± 0.068	0.795SerTrp: 0.795 ± 0.026	2.28SerTyr: 2.28 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.317ThrAla: 4.317 ± 0.061	0.5ThrCys: 0.5 ± 0.022	2.928ThrAsp: 2.928 ± 0.084	3.501ThrGlu: 3.501 ± 0.052	2.265ThrPhe: 2.265 ± 0.044	3.887ThrGly: 3.887 ± 0.073	1.265ThrHis: 1.265 ± 0.035	3.967ThrIle: 3.967 ± 0.077	2.835ThrLys: 2.835 ± 0.048	6.365ThrLeu: 6.365 ± 0.081	1.224ThrMet: 1.224 ± 0.032	2.388ThrAsn: 2.388 ± 0.052	2.688ThrPro: 2.688 ± 0.051	2.481ThrGln: 2.481 ± 0.053	2.087ThrArg: 2.087 ± 0.04	3.663ThrSer: 3.663 ± 0.058	3.232ThrThr: 3.232 ± 0.057	3.881ThrVal: 3.881 ± 0.091	0.615ThrTrp: 0.615 ± 0.025	1.639ThrTyr: 1.639 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	5.696ValAla: 5.696 ± 0.087	0.732ValCys: 0.732 ± 0.025	3.962ValAsp: 3.962 ± 0.067	4.503ValGlu: 4.503 ± 0.068	2.789ValPhe: 2.789 ± 0.054	4.449ValGly: 4.449 ± 0.071	1.177ValHis: 1.177 ± 0.033	5.081ValIle: 5.081 ± 0.073	3.746ValLys: 3.746 ± 0.067	6.332ValLeu: 6.332 ± 0.083	1.952ValMet: 1.952 ± 0.042	3.22ValAsn: 3.22 ± 0.053	2.379ValPro: 2.379 ± 0.046	2.177ValGln: 2.177 ± 0.041	2.629ValArg: 2.629 ± 0.042	4.837ValSer: 4.837 ± 0.055	4.122ValThr: 4.122 ± 0.089	4.882ValVal: 4.882 ± 0.068	0.719ValTrp: 0.719 ± 0.025	1.814ValTyr: 1.814 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.765TrpAla: 0.765 ± 0.028	0.162TrpCys: 0.162 ± 0.012	0.62TrpAsp: 0.62 ± 0.026	0.581TrpGlu: 0.581 ± 0.022	0.584TrpPhe: 0.584 ± 0.026	0.772TrpGly: 0.772 ± 0.022	0.297TrpHis: 0.297 ± 0.016	0.743TrpIle: 0.743 ± 0.026	0.647TrpLys: 0.647 ± 0.024	1.606TrpLeu: 1.606 ± 0.043	0.324TrpMet: 0.324 ± 0.016	0.54TrpAsn: 0.54 ± 0.022	0.403TrpPro: 0.403 ± 0.016	0.695TrpGln: 0.695 ± 0.026	0.55TrpArg: 0.55 ± 0.02	0.745TrpSer: 0.745 ± 0.028	0.52TrpThr: 0.52 ± 0.031	0.775TrpVal: 0.775 ± 0.028	0.195TrpTrp: 0.195 ± 0.012	0.363TrpTyr: 0.363 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.191TyrAla: 2.191 ± 0.044	0.371TyrCys: 0.371 ± 0.02	1.708TyrAsp: 1.708 ± 0.048	1.616TyrGlu: 1.616 ± 0.039	1.474TyrPhe: 1.474 ± 0.04	2.157TyrGly: 2.157 ± 0.043	0.787TyrHis: 0.787 ± 0.029	1.914TyrIle: 1.914 ± 0.043	1.681TyrLys: 1.681 ± 0.046	3.412TyrLeu: 3.412 ± 0.061	0.688TyrMet: 0.688 ± 0.024	1.384TyrAsn: 1.384 ± 0.035	1.364TyrPro: 1.364 ± 0.034	1.94TyrGln: 1.94 ± 0.041	1.564TyrArg: 1.564 ± 0.036	2.255TyrSer: 2.255 ± 0.053	1.579TyrThr: 1.579 ± 0.035	1.829TyrVal: 1.829 ± 0.035	0.479TyrTrp: 0.479 ± 0.022	1.052TyrTyr: 1.052 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3813 proteins (1236819 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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