Amino acid dipepetide frequency for Hubei picorna-like virus 79

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.176AlaAla: 5.176 ± 2.142
0.0AlaCys: 0.0 ± 0.0
3.106AlaAsp: 3.106 ± 0.368
2.07AlaGlu: 2.07 ± 0.149
2.761AlaPhe: 2.761 ± 0.395
3.451AlaGly: 3.451 ± 0.641
1.38AlaHis: 1.38 ± 0.098
2.415AlaIle: 2.415 ± 0.024
2.07AlaLys: 2.07 ± 1.032
6.211AlaLeu: 6.211 ± 0.735
4.141AlaMet: 4.141 ± 0.689
2.761AlaAsn: 2.761 ± 0.985
2.761AlaPro: 2.761 ± 0.395
2.761AlaGln: 2.761 ± 0.395
2.07AlaArg: 2.07 ± 0.149
4.486AlaSer: 4.486 ± 1.306
3.451AlaThr: 3.451 ± 0.641
2.415AlaVal: 2.415 ± 0.024
0.0AlaTrp: 0.0 ± 0.0
4.831AlaTyr: 4.831 ± 0.637
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.345CysCys: 0.345 ± 0.172
0.69CysAsp: 0.69 ± 0.344
0.69CysGlu: 0.69 ± 0.837
0.345CysPhe: 0.345 ± 0.172
0.69CysGly: 0.69 ± 0.344
0.0CysHis: 0.0 ± 0.0
1.38CysIle: 1.38 ± 0.688
0.69CysLys: 0.69 ± 0.246
1.035CysLeu: 1.035 ± 0.516
0.0CysMet: 0.0 ± 0.0
0.69CysAsn: 0.69 ± 0.344
0.69CysPro: 0.69 ± 0.344
1.38CysGln: 1.38 ± 0.688
0.0CysArg: 0.0 ± 0.0
1.38CysSer: 1.38 ± 0.688
1.38CysThr: 1.38 ± 0.688
2.415CysVal: 2.415 ± 0.614
0.345CysTrp: 0.345 ± 0.172
1.035CysTyr: 1.035 ± 0.516
0.0CysXaa: 0.0 ± 0.0
Asp
3.451AspAla: 3.451 ± 0.051
1.035AspCys: 1.035 ± 0.516
4.486AspAsp: 4.486 ± 0.465
1.725AspGlu: 1.725 ± 0.27
6.901AspPhe: 6.901 ± 1.67
2.415AspGly: 2.415 ± 0.614
0.345AspHis: 0.345 ± 0.172
4.141AspIle: 4.141 ± 0.884
2.415AspLys: 2.415 ± 1.204
6.211AspLeu: 6.211 ± 1.036
0.69AspMet: 0.69 ± 0.344
1.725AspAsn: 1.725 ± 0.27
4.486AspPro: 4.486 ± 1.306
2.07AspGln: 2.07 ± 0.442
1.725AspArg: 1.725 ± 0.27
4.486AspSer: 4.486 ± 1.646
3.451AspThr: 3.451 ± 1.822
2.07AspVal: 2.07 ± 0.149
0.69AspTrp: 0.69 ± 0.344
3.106AspTyr: 3.106 ± 0.223
0.0AspXaa: 0.0 ± 0.0
Glu
3.796GluAla: 3.796 ± 1.892
0.345GluCys: 0.345 ± 0.172
1.035GluAsp: 1.035 ± 0.074
3.451GluGlu: 3.451 ± 1.13
3.106GluPhe: 3.106 ± 0.223
1.035GluGly: 1.035 ± 0.665
1.725GluHis: 1.725 ± 0.911
4.486GluIle: 4.486 ± 1.056
2.415GluLys: 2.415 ± 0.614
4.486GluLeu: 4.486 ± 0.465
1.035GluMet: 1.035 ± 0.074
4.486GluAsn: 4.486 ± 0.125
3.451GluPro: 3.451 ± 1.13
2.415GluGln: 2.415 ± 0.024
1.035GluArg: 1.035 ± 0.516
3.106GluSer: 3.106 ± 0.813
1.38GluThr: 1.38 ± 0.493
1.725GluVal: 1.725 ± 0.86
0.0GluTrp: 0.0 ± 0.0
2.07GluTyr: 2.07 ± 1.032
0.0GluXaa: 0.0 ± 0.0
Phe
2.761PheAla: 2.761 ± 0.985
1.035PheCys: 1.035 ± 0.516
3.106PheAsp: 3.106 ± 0.813
2.415PheGlu: 2.415 ± 0.614
2.415PhePhe: 2.415 ± 0.024
2.07PheGly: 2.07 ± 0.442
0.345PheHis: 0.345 ± 0.418
2.761PheIle: 2.761 ± 0.395
3.451PheLys: 3.451 ± 0.051
5.176PheLeu: 5.176 ± 2.58
0.69PheMet: 0.69 ± 0.344
3.451PheAsn: 3.451 ± 0.54
3.106PhePro: 3.106 ± 0.223
1.38PheGln: 1.38 ± 0.493
3.106PheArg: 3.106 ± 0.813
4.486PheSer: 4.486 ± 1.646
2.415PheThr: 2.415 ± 0.567
4.141PheVal: 4.141 ± 0.297
0.69PheTrp: 0.69 ± 0.246
1.725PheTyr: 1.725 ± 0.27
0.0PheXaa: 0.0 ± 0.0
Gly
1.725GlyAla: 1.725 ± 1.501
0.345GlyCys: 0.345 ± 0.172
2.07GlyAsp: 2.07 ± 0.739
3.106GlyGlu: 3.106 ± 0.368
1.725GlyPhe: 1.725 ± 0.321
1.725GlyGly: 1.725 ± 0.27
0.0GlyHis: 0.0 ± 0.0
2.415GlyIle: 2.415 ± 0.567
3.796GlyLys: 3.796 ± 1.302
5.176GlyLeu: 5.176 ± 0.809
0.69GlyMet: 0.69 ± 0.204
3.106GlyAsn: 3.106 ± 0.813
1.725GlyPro: 1.725 ± 0.321
2.07GlyGln: 2.07 ± 0.149
2.415GlyArg: 2.415 ± 0.614
2.07GlySer: 2.07 ± 0.149
2.415GlyThr: 2.415 ± 1.157
2.761GlyVal: 2.761 ± 0.395
0.0GlyTrp: 0.0 ± 0.0
2.415GlyTyr: 2.415 ± 1.204
0.0GlyXaa: 0.0 ± 0.0
His
1.725HisAla: 1.725 ± 0.27
0.0HisCys: 0.0 ± 0.0
0.345HisAsp: 0.345 ± 0.172
1.725HisGlu: 1.725 ± 0.321
2.761HisPhe: 2.761 ± 0.196
1.035HisGly: 1.035 ± 0.516
1.725HisHis: 1.725 ± 0.27
1.38HisIle: 1.38 ± 0.688
2.07HisLys: 2.07 ± 0.442
2.415HisLeu: 2.415 ± 1.157
0.69HisMet: 0.69 ± 0.344
2.415HisAsn: 2.415 ± 0.567
2.415HisPro: 2.415 ± 0.614
1.035HisGln: 1.035 ± 0.516
2.07HisArg: 2.07 ± 0.442
2.761HisSer: 2.761 ± 0.985
1.035HisThr: 1.035 ± 0.665
1.38HisVal: 1.38 ± 0.098
0.345HisTrp: 0.345 ± 0.172
0.345HisTyr: 0.345 ± 0.172
0.0HisXaa: 0.0 ± 0.0
Ile
1.725IleAla: 1.725 ± 0.86
1.035IleCys: 1.035 ± 0.516
3.451IleAsp: 3.451 ± 0.051
3.796IleGlu: 3.796 ± 0.712
2.07IlePhe: 2.07 ± 0.149
3.796IleGly: 3.796 ± 0.121
2.07IleHis: 2.07 ± 0.442
4.486IleIle: 4.486 ± 0.465
5.176IleLys: 5.176 ± 0.219
4.831IleLeu: 4.831 ± 0.047
1.725IleMet: 1.725 ± 0.86
5.176IleAsn: 5.176 ± 0.962
3.451IlePro: 3.451 ± 1.231
5.176IleGln: 5.176 ± 0.809
2.761IleArg: 2.761 ± 1.376
4.141IleSer: 4.141 ± 0.297
6.901IleThr: 6.901 ± 1.67
2.07IleVal: 2.07 ± 0.442
0.345IleTrp: 0.345 ± 0.172
2.07IleTyr: 2.07 ± 0.149
0.0IleXaa: 0.0 ± 0.0
Lys
4.486LysAla: 4.486 ± 1.056
2.07LysCys: 2.07 ± 0.442
5.866LysAsp: 5.866 ± 1.744
3.796LysGlu: 3.796 ± 1.302
1.035LysPhe: 1.035 ± 0.074
1.38LysGly: 1.38 ± 0.098
3.451LysHis: 3.451 ± 1.13
4.141LysIle: 4.141 ± 2.064
3.106LysLys: 3.106 ± 0.958
5.176LysLeu: 5.176 ± 0.962
1.725LysMet: 1.725 ± 0.86
3.796LysAsn: 3.796 ± 0.712
3.451LysPro: 3.451 ± 1.13
0.69LysGln: 0.69 ± 0.344
1.035LysArg: 1.035 ± 0.516
3.106LysSer: 3.106 ± 1.548
4.486LysThr: 4.486 ± 0.715
2.07LysVal: 2.07 ± 0.442
0.69LysTrp: 0.69 ± 0.344
2.415LysTyr: 2.415 ± 0.614
0.0LysXaa: 0.0 ± 0.0
Leu
5.521LeuAla: 5.521 ± 0.79
1.035LeuCys: 1.035 ± 0.516
4.831LeuAsp: 4.831 ± 0.637
3.451LeuGlu: 3.451 ± 1.231
5.521LeuPhe: 5.521 ± 0.981
3.796LeuGly: 3.796 ± 1.65
1.38LeuHis: 1.38 ± 0.098
5.521LeuIle: 5.521 ± 0.391
5.521LeuLys: 5.521 ± 1.572
5.521LeuLeu: 5.521 ± 1.97
2.07LeuMet: 2.07 ± 0.442
7.591LeuAsn: 7.591 ± 2.119
3.451LeuPro: 3.451 ± 0.051
2.07LeuGln: 2.07 ± 0.442
4.831LeuArg: 4.831 ± 0.637
9.317LeuSer: 9.317 ± 1.849
9.317LeuThr: 9.317 ± 3.03
5.176LeuVal: 5.176 ± 1.4
0.345LeuTrp: 0.345 ± 0.172
4.141LeuTyr: 4.141 ± 0.887
0.0LeuXaa: 0.0 ± 0.0
Met
1.725MetAla: 1.725 ± 0.27
0.69MetCys: 0.69 ± 0.344
2.07MetAsp: 2.07 ± 0.442
0.69MetGlu: 0.69 ± 0.344
1.38MetPhe: 1.38 ± 0.098
0.345MetGly: 0.345 ± 0.172
1.38MetHis: 1.38 ± 0.098
2.761MetIle: 2.761 ± 0.786
2.415MetLys: 2.415 ± 1.204
2.07MetLeu: 2.07 ± 0.149
0.0MetMet: 0.0 ± 0.0
0.69MetAsn: 0.69 ± 0.344
0.345MetPro: 0.345 ± 0.172
0.0MetGln: 0.0 ± 0.0
0.69MetArg: 0.69 ± 0.837
0.69MetSer: 0.69 ± 0.246
1.38MetThr: 1.38 ± 0.098
1.035MetVal: 1.035 ± 0.074
0.345MetTrp: 0.345 ± 0.418
2.07MetTyr: 2.07 ± 1.032
0.0MetXaa: 0.0 ± 0.0
Asn
2.07AsnAla: 2.07 ± 0.739
0.345AsnCys: 0.345 ± 0.172
2.761AsnAsp: 2.761 ± 0.196
2.415AsnGlu: 2.415 ± 0.614
1.725AsnPhe: 1.725 ± 0.321
3.451AsnGly: 3.451 ± 1.13
0.345AsnHis: 0.345 ± 0.172
5.176AsnIle: 5.176 ± 0.371
2.415AsnLys: 2.415 ± 0.024
4.831AsnLeu: 4.831 ± 1.134
1.035AsnMet: 1.035 ± 0.516
4.486AsnAsn: 4.486 ± 1.306
7.246AsnPro: 7.246 ± 2.291
2.415AsnGln: 2.415 ± 1.157
3.106AsnArg: 3.106 ± 0.813
5.176AsnSer: 5.176 ± 0.962
7.591AsnThr: 7.591 ± 0.243
2.761AsnVal: 2.761 ± 0.985
1.38AsnTrp: 1.38 ± 0.098
2.415AsnTyr: 2.415 ± 0.567
0.0AsnXaa: 0.0 ± 0.0
Pro
2.761ProAla: 2.761 ± 0.395
1.38ProCys: 1.38 ± 0.493
4.831ProAsp: 4.831 ± 0.543
2.07ProGlu: 2.07 ± 0.442
3.796ProPhe: 3.796 ± 1.059
2.07ProGly: 2.07 ± 1.329
2.415ProHis: 2.415 ± 0.024
3.451ProIle: 3.451 ± 0.051
2.415ProLys: 2.415 ± 0.614
4.141ProLeu: 4.141 ± 0.297
0.69ProMet: 0.69 ± 0.246
2.07ProAsn: 2.07 ± 0.149
3.451ProPro: 3.451 ± 0.54
2.761ProGln: 2.761 ± 0.395
1.725ProArg: 1.725 ± 0.27
6.211ProSer: 6.211 ± 1.036
5.176ProThr: 5.176 ± 3.323
3.796ProVal: 3.796 ± 0.469
1.035ProTrp: 1.035 ± 0.516
1.38ProTyr: 1.38 ± 0.493
0.0ProXaa: 0.0 ± 0.0
Gln
2.761GlnAla: 2.761 ± 0.786
0.69GlnCys: 0.69 ± 0.344
1.38GlnAsp: 1.38 ± 0.688
3.106GlnGlu: 3.106 ± 0.958
2.415GlnPhe: 2.415 ± 0.024
1.38GlnGly: 1.38 ± 0.098
1.035GlnHis: 1.035 ± 0.074
2.07GlnIle: 2.07 ± 0.442
2.761GlnLys: 2.761 ± 0.196
3.106GlnLeu: 3.106 ± 0.958
0.69GlnMet: 0.69 ± 0.246
2.415GlnAsn: 2.415 ± 0.567
2.761GlnPro: 2.761 ± 0.196
0.69GlnGln: 0.69 ± 0.246
1.035GlnArg: 1.035 ± 0.516
2.761GlnSer: 2.761 ± 2.166
2.415GlnThr: 2.415 ± 0.024
1.38GlnVal: 1.38 ± 1.673
1.725GlnTrp: 1.725 ± 0.27
1.035GlnTyr: 1.035 ± 0.074
0.0GlnXaa: 0.0 ± 0.0
Arg
2.07ArgAla: 2.07 ± 0.442
0.69ArgCys: 0.69 ± 0.344
2.07ArgAsp: 2.07 ± 0.442
2.07ArgGlu: 2.07 ± 0.442
2.761ArgPhe: 2.761 ± 0.196
3.106ArgGly: 3.106 ± 0.223
1.035ArgHis: 1.035 ± 0.074
1.725ArgIle: 1.725 ± 0.27
2.761ArgLys: 2.761 ± 0.196
3.106ArgLeu: 3.106 ± 0.223
0.69ArgMet: 0.69 ± 0.344
3.106ArgAsn: 3.106 ± 0.223
2.761ArgPro: 2.761 ± 0.196
1.725ArgGln: 1.725 ± 0.27
3.106ArgArg: 3.106 ± 0.223
4.486ArgSer: 4.486 ± 0.125
3.451ArgThr: 3.451 ± 0.54
0.69ArgVal: 0.69 ± 0.246
0.345ArgTrp: 0.345 ± 0.172
1.035ArgTyr: 1.035 ± 0.665
0.0ArgXaa: 0.0 ± 0.0
Ser
4.831SerAla: 4.831 ± 0.543
1.035SerCys: 1.035 ± 0.516
3.796SerAsp: 3.796 ± 1.059
2.761SerGlu: 2.761 ± 0.196
2.415SerPhe: 2.415 ± 0.024
3.796SerGly: 3.796 ± 0.469
3.106SerHis: 3.106 ± 1.994
6.211SerIle: 6.211 ± 0.145
3.796SerLys: 3.796 ± 1.892
10.007SerLeu: 10.007 ± 2.686
1.725SerMet: 1.725 ± 0.27
3.106SerAsn: 3.106 ± 0.813
3.106SerPro: 3.106 ± 1.403
2.415SerGln: 2.415 ± 1.204
3.106SerArg: 3.106 ± 1.403
6.211SerSer: 6.211 ± 0.446
6.901SerThr: 6.901 ± 0.692
4.486SerVal: 4.486 ± 1.056
1.035SerTrp: 1.035 ± 0.516
2.761SerTyr: 2.761 ± 0.395
0.0SerXaa: 0.0 ± 0.0
Thr
5.176ThrAla: 5.176 ± 0.962
0.69ThrCys: 0.69 ± 0.344
3.796ThrAsp: 3.796 ± 0.469
3.796ThrGlu: 3.796 ± 0.469
4.141ThrPhe: 4.141 ± 0.884
2.415ThrGly: 2.415 ± 0.567
2.761ThrHis: 2.761 ± 0.786
6.901ThrIle: 6.901 ± 1.282
3.106ThrLys: 3.106 ± 0.958
7.246ThrLeu: 7.246 ± 1.11
0.69ThrMet: 0.69 ± 0.344
4.831ThrAsn: 4.831 ± 1.134
3.796ThrPro: 3.796 ± 2.83
2.761ThrGln: 2.761 ± 1.575
2.415ThrArg: 2.415 ± 0.614
4.831ThrSer: 4.831 ± 0.637
6.211ThrThr: 6.211 ± 2.807
4.831ThrVal: 4.831 ± 2.905
1.38ThrTrp: 1.38 ± 0.688
3.106ThrTyr: 3.106 ± 0.813
0.0ThrXaa: 0.0 ± 0.0
Val
4.486ValAla: 4.486 ± 1.896
0.69ValCys: 0.69 ± 0.246
2.415ValAsp: 2.415 ± 1.204
1.035ValGlu: 1.035 ± 0.516
1.035ValPhe: 1.035 ± 0.074
2.761ValGly: 2.761 ± 0.395
2.761ValHis: 2.761 ± 0.786
2.07ValIle: 2.07 ± 1.032
3.451ValLys: 3.451 ± 1.72
4.486ValLeu: 4.486 ± 1.306
1.38ValMet: 1.38 ± 0.493
3.796ValAsn: 3.796 ± 0.469
2.415ValPro: 2.415 ± 1.157
1.38ValGln: 1.38 ± 0.688
3.451ValArg: 3.451 ± 0.641
2.761ValSer: 2.761 ± 1.575
2.761ValThr: 2.761 ± 0.786
3.796ValVal: 3.796 ± 0.712
1.035ValTrp: 1.035 ± 0.516
4.141ValTyr: 4.141 ± 0.887
0.0ValXaa: 0.0 ± 0.0
Trp
0.345TrpAla: 0.345 ± 0.172
1.38TrpCys: 1.38 ± 0.688
0.69TrpAsp: 0.69 ± 0.344
1.035TrpGlu: 1.035 ± 0.516
0.345TrpPhe: 0.345 ± 0.172
0.345TrpGly: 0.345 ± 0.172
0.345TrpHis: 0.345 ± 0.172
0.0TrpIle: 0.0 ± 0.0
1.035TrpLys: 1.035 ± 0.074
0.69TrpLeu: 0.69 ± 0.344
0.69TrpMet: 0.69 ± 0.344
0.345TrpAsn: 0.345 ± 0.172
0.345TrpPro: 0.345 ± 0.172
0.69TrpGln: 0.69 ± 0.344
0.345TrpArg: 0.345 ± 0.418
1.035TrpSer: 1.035 ± 0.074
0.345TrpThr: 0.345 ± 0.172
0.69TrpVal: 0.69 ± 0.344
0.0TrpTrp: 0.0 ± 0.0
1.035TrpTyr: 1.035 ± 0.074
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.725TyrAla: 1.725 ± 0.911
0.345TyrCys: 0.345 ± 0.172
4.831TyrAsp: 4.831 ± 1.228
1.38TyrGlu: 1.38 ± 0.098
2.07TyrPhe: 2.07 ± 0.149
1.035TyrGly: 1.035 ± 0.516
2.07TyrHis: 2.07 ± 0.442
2.761TyrIle: 2.761 ± 0.395
3.106TyrLys: 3.106 ± 0.223
4.486TyrLeu: 4.486 ± 0.715
1.38TyrMet: 1.38 ± 0.688
3.106TyrAsn: 3.106 ± 0.368
2.415TyrPro: 2.415 ± 1.157
1.725TyrGln: 1.725 ± 0.911
2.761TyrArg: 2.761 ± 1.376
3.106TyrSer: 3.106 ± 0.223
2.415TyrThr: 2.415 ± 0.024
2.415TyrVal: 2.415 ± 0.024
0.0TyrTrp: 0.0 ± 0.0
3.106TyrTyr: 3.106 ± 0.223
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski