Amino acid dipepetide frequency for Treponema maltophilum ATCC 51939

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.455AlaAla: 11.455 ± 0.201	1.255AlaCys: 1.255 ± 0.044	5.855AlaAsp: 5.855 ± 0.113	6.737AlaGlu: 6.737 ± 0.115	4.521AlaPhe: 4.521 ± 0.082	7.436AlaGly: 7.436 ± 0.114	1.552AlaHis: 1.552 ± 0.047	4.206AlaIle: 4.206 ± 0.078	5.249AlaLys: 5.249 ± 0.091	10.056AlaLeu: 10.056 ± 0.12	1.884AlaMet: 1.884 ± 0.05	2.655AlaAsn: 2.655 ± 0.062	2.797AlaPro: 2.797 ± 0.064	3.543AlaGln: 3.543 ± 0.065	3.975AlaArg: 3.975 ± 0.089	5.944AlaSer: 5.944 ± 0.106	2.714AlaThr: 2.714 ± 0.068	8.348AlaVal: 8.348 ± 0.099	0.721AlaTrp: 0.721 ± 0.031	2.972AlaTyr: 2.972 ± 0.066	0.0AlaXaa: 0.0 ± 0.0
Cys	1.774CysAla: 1.774 ± 0.058	0.22CysCys: 0.22 ± 0.017	0.682CysAsp: 0.682 ± 0.03	0.676CysGlu: 0.676 ± 0.03	0.731CysPhe: 0.731 ± 0.03	1.264CysGly: 1.264 ± 0.052	0.168CysHis: 0.168 ± 0.013	1.03CysIle: 1.03 ± 0.039	0.736CysLys: 0.736 ± 0.033	1.11CysLeu: 1.11 ± 0.037	0.331CysMet: 0.331 ± 0.02	0.396CysAsn: 0.396 ± 0.023	0.553CysPro: 0.553 ± 0.028	0.169CysGln: 0.169 ± 0.016	0.758CysArg: 0.758 ± 0.035	0.992CysSer: 0.992 ± 0.037	0.9CysThr: 0.9 ± 0.042	0.95CysVal: 0.95 ± 0.038	0.121CysTrp: 0.121 ± 0.013	0.377CysTyr: 0.377 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	5.002AspAla: 5.002 ± 0.102	0.714AspCys: 0.714 ± 0.031	2.565AspAsp: 2.565 ± 0.069	3.956AspGlu: 3.956 ± 0.081	3.275AspPhe: 3.275 ± 0.076	3.916AspGly: 3.916 ± 0.078	0.508AspHis: 0.508 ± 0.023	4.442AspIle: 4.442 ± 0.085	3.467AspLys: 3.467 ± 0.073	4.425AspLeu: 4.425 ± 0.09	1.457AspMet: 1.457 ± 0.047	1.819AspAsn: 1.819 ± 0.051	2.026AspPro: 2.026 ± 0.056	0.783AspGln: 0.783 ± 0.034	2.108AspArg: 2.108 ± 0.066	3.291AspSer: 3.291 ± 0.067	3.175AspThr: 3.175 ± 0.072	3.325AspVal: 3.325 ± 0.073	0.652AspTrp: 0.652 ± 0.031	2.169AspTyr: 2.169 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	5.216GluAla: 5.216 ± 0.097	0.671GluCys: 0.671 ± 0.033	3.011GluAsp: 3.011 ± 0.067	4.131GluGlu: 4.131 ± 0.095	2.458GluPhe: 2.458 ± 0.059	3.538GluGly: 3.538 ± 0.06	1.19GluHis: 1.19 ± 0.04	4.269GluIle: 4.269 ± 0.075	6.483GluLys: 6.483 ± 0.118	5.733GluLeu: 5.733 ± 0.094	1.344GluMet: 1.344 ± 0.047	3.841GluAsn: 3.841 ± 0.075	1.843GluPro: 1.843 ± 0.062	2.576GluGln: 2.576 ± 0.062	3.832GluArg: 3.832 ± 0.084	3.565GluSer: 3.565 ± 0.079	3.429GluThr: 3.429 ± 0.066	3.119GluVal: 3.119 ± 0.066	0.592GluTrp: 0.592 ± 0.031	2.244GluTyr: 2.244 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	4.782PheAla: 4.782 ± 0.087	0.874PheCys: 0.874 ± 0.037	2.823PheAsp: 2.823 ± 0.075	2.797PheGlu: 2.797 ± 0.062	3.252PhePhe: 3.252 ± 0.082	3.427PheGly: 3.427 ± 0.076	0.616PheHis: 0.616 ± 0.03	3.746PheIle: 3.746 ± 0.08	2.699PheLys: 2.699 ± 0.052	4.521PheLeu: 4.521 ± 0.086	1.167PheMet: 1.167 ± 0.042	1.843PheAsn: 1.843 ± 0.06	1.965PhePro: 1.965 ± 0.055	0.998PheGln: 0.998 ± 0.04	1.902PheArg: 1.902 ± 0.049	4.187PheSer: 4.187 ± 0.083	3.012PheThr: 3.012 ± 0.067	3.091PheVal: 3.091 ± 0.078	0.522PheTrp: 0.522 ± 0.029	1.925PheTyr: 1.925 ± 0.059	0.0PheXaa: 0.0 ± 0.0
Gly	5.966GlyAla: 5.966 ± 0.099	1.062GlyCys: 1.062 ± 0.045	3.082GlyAsp: 3.082 ± 0.06	4.112GlyGlu: 4.112 ± 0.069	3.765GlyPhe: 3.765 ± 0.069	5.227GlyGly: 5.227 ± 0.121	0.868GlyHis: 0.868 ± 0.032	5.701GlyIle: 5.701 ± 0.095	5.777GlyLys: 5.777 ± 0.087	5.878GlyLeu: 5.878 ± 0.09	1.911GlyMet: 1.911 ± 0.053	2.73GlyAsn: 2.73 ± 0.081	1.474GlyPro: 1.474 ± 0.047	1.745GlyGln: 1.745 ± 0.05	3.132GlyArg: 3.132 ± 0.069	4.717GlySer: 4.717 ± 0.082	4.735GlyThr: 4.735 ± 0.1	4.234GlyVal: 4.234 ± 0.082	0.7GlyTrp: 0.7 ± 0.032	2.34GlyTyr: 2.34 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.354HisAla: 1.354 ± 0.037	0.275HisCys: 0.275 ± 0.019	0.713HisAsp: 0.713 ± 0.03	0.86HisGlu: 0.86 ± 0.036	0.788HisPhe: 0.788 ± 0.027	1.133HisGly: 1.133 ± 0.038	0.254HisHis: 0.254 ± 0.02	1.398HisIle: 1.398 ± 0.047	1.003HisLys: 1.003 ± 0.035	1.328HisLeu: 1.328 ± 0.048	0.355HisMet: 0.355 ± 0.021	0.705HisAsn: 0.705 ± 0.034	0.817HisPro: 0.817 ± 0.028	0.321HisGln: 0.321 ± 0.017	0.785HisArg: 0.785 ± 0.032	0.945HisSer: 0.945 ± 0.032	0.99HisThr: 0.99 ± 0.038	0.845HisVal: 0.845 ± 0.036	0.159HisTrp: 0.159 ± 0.014	0.576HisTyr: 0.576 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.598IleAla: 6.598 ± 0.103	0.921IleCys: 0.921 ± 0.04	4.131IleAsp: 4.131 ± 0.076	4.267IleGlu: 4.267 ± 0.078	3.0IlePhe: 3.0 ± 0.076	4.743IleGly: 4.743 ± 0.108	1.102IleHis: 1.102 ± 0.037	4.806IleIle: 4.806 ± 0.097	4.347IleLys: 4.347 ± 0.073	6.163IleLeu: 6.163 ± 0.108	1.399IleMet: 1.399 ± 0.05	2.548IleAsn: 2.548 ± 0.062	3.505IlePro: 3.505 ± 0.073	2.07IleGln: 2.07 ± 0.053	3.637IleArg: 3.637 ± 0.065	4.253IleSer: 4.253 ± 0.083	3.842IleThr: 3.842 ± 0.071	4.663IleVal: 4.663 ± 0.089	0.436IleTrp: 0.436 ± 0.026	1.932IleTyr: 1.932 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	5.956LysAla: 5.956 ± 0.089	0.437LysCys: 0.437 ± 0.024	3.882LysAsp: 3.882 ± 0.081	4.918LysGlu: 4.918 ± 0.093	1.734LysPhe: 1.734 ± 0.054	4.08LysGly: 4.08 ± 0.066	1.03LysHis: 1.03 ± 0.039	5.047LysIle: 5.047 ± 0.088	6.683LysLys: 6.683 ± 0.103	5.683LysLeu: 5.683 ± 0.082	1.596LysMet: 1.596 ± 0.05	4.479LysAsn: 4.479 ± 0.071	2.373LysPro: 2.373 ± 0.056	2.021LysGln: 2.021 ± 0.05	3.519LysArg: 3.519 ± 0.068	3.755LysSer: 3.755 ± 0.08	5.18LysThr: 5.18 ± 0.093	3.3LysVal: 3.3 ± 0.077	0.487LysTrp: 0.487 ± 0.026	2.088LysTyr: 2.088 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	8.067LeuAla: 8.067 ± 0.111	1.983LeuCys: 1.983 ± 0.054	4.577LeuAsp: 4.577 ± 0.083	5.33LeuGlu: 5.33 ± 0.09	5.391LeuPhe: 5.391 ± 0.112	5.361LeuGly: 5.361 ± 0.104	1.777LeuHis: 1.777 ± 0.052	6.361LeuIle: 6.361 ± 0.122	6.273LeuLys: 6.273 ± 0.093	9.222LeuLeu: 9.222 ± 0.153	2.112LeuMet: 2.112 ± 0.056	4.002LeuAsn: 4.002 ± 0.067	4.233LeuPro: 4.233 ± 0.074	2.896LeuGln: 2.896 ± 0.07	4.49LeuArg: 4.49 ± 0.082	7.378LeuSer: 7.378 ± 0.105	5.312LeuThr: 5.312 ± 0.088	5.165LeuVal: 5.165 ± 0.083	0.995LeuTrp: 0.995 ± 0.037	3.815LeuTyr: 3.815 ± 0.077	0.0LeuXaa: 0.0 ± 0.0
Met	1.714MetAla: 1.714 ± 0.05	0.282MetCys: 0.282 ± 0.018	1.101MetAsp: 1.101 ± 0.041	1.382MetGlu: 1.382 ± 0.045	0.922MetPhe: 0.922 ± 0.035	1.48MetGly: 1.48 ± 0.056	0.445MetHis: 0.445 ± 0.027	1.467MetIle: 1.467 ± 0.046	1.942MetLys: 1.942 ± 0.043	2.317MetLeu: 2.317 ± 0.059	0.6MetMet: 0.6 ± 0.03	1.349MetAsn: 1.349 ± 0.041	1.055MetPro: 1.055 ± 0.035	0.964MetGln: 0.964 ± 0.039	1.226MetArg: 1.226 ± 0.037	1.471MetSer: 1.471 ± 0.037	1.211MetThr: 1.211 ± 0.041	1.155MetVal: 1.155 ± 0.041	0.153MetTrp: 0.153 ± 0.014	0.802MetTyr: 0.802 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	4.134AsnAla: 4.134 ± 0.077	0.525AsnCys: 0.525 ± 0.029	1.996AsnAsp: 1.996 ± 0.048	2.623AsnGlu: 2.623 ± 0.062	1.776AsnPhe: 1.776 ± 0.049	3.398AsnGly: 3.398 ± 0.075	0.521AsnHis: 0.521 ± 0.026	3.28AsnIle: 3.28 ± 0.071	2.543AsnLys: 2.543 ± 0.063	3.663AsnLeu: 3.663 ± 0.073	1.123AsnMet: 1.123 ± 0.038	1.56AsnAsn: 1.56 ± 0.056	2.222AsnPro: 2.222 ± 0.058	1.019AsnGln: 1.019 ± 0.04	2.11AsnArg: 2.11 ± 0.057	2.112AsnSer: 2.112 ± 0.057	2.446AsnThr: 2.446 ± 0.065	2.422AsnVal: 2.422 ± 0.053	0.431AsnTrp: 0.431 ± 0.024	1.411AsnTyr: 1.411 ± 0.05	0.0AsnXaa: 0.0 ± 0.0
Pro	4.073ProAla: 4.073 ± 0.089	0.447ProCys: 0.447 ± 0.028	2.501ProAsp: 2.501 ± 0.061	3.092ProGlu: 3.092 ± 0.068	2.143ProPhe: 2.143 ± 0.053	2.358ProGly: 2.358 ± 0.056	0.756ProHis: 0.756 ± 0.032	1.969ProIle: 1.969 ± 0.056	1.795ProLys: 1.795 ± 0.048	4.005ProLeu: 4.005 ± 0.08	0.707ProMet: 0.707 ± 0.03	1.239ProAsn: 1.239 ± 0.037	1.333ProPro: 1.333 ± 0.046	1.301ProGln: 1.301 ± 0.047	1.346ProArg: 1.346 ± 0.044	2.544ProSer: 2.544 ± 0.058	1.394ProThr: 1.394 ± 0.039	3.56ProVal: 3.56 ± 0.071	0.361ProTrp: 0.361 ± 0.023	1.431ProTyr: 1.431 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.73GlnAla: 2.73 ± 0.07	0.286GlnCys: 0.286 ± 0.02	1.262GlnAsp: 1.262 ± 0.039	1.561GlnGlu: 1.561 ± 0.057	1.099GlnPhe: 1.099 ± 0.044	1.697GlnGly: 1.697 ± 0.047	0.402GlnHis: 0.402 ± 0.022	1.968GlnIle: 1.968 ± 0.065	3.127GlnLys: 3.127 ± 0.067	2.303GlnLeu: 2.303 ± 0.061	0.725GlnMet: 0.725 ± 0.033	1.889GlnAsn: 1.889 ± 0.048	0.857GlnPro: 0.857 ± 0.034	0.87GlnGln: 0.87 ± 0.039	1.358GlnArg: 1.358 ± 0.046	2.215GlnSer: 2.215 ± 0.057	2.102GlnThr: 2.102 ± 0.053	1.531GlnVal: 1.531 ± 0.041	0.317GlnTrp: 0.317 ± 0.02	1.039GlnTyr: 1.039 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	3.659ArgAla: 3.659 ± 0.072	0.603ArgCys: 0.603 ± 0.029	2.312ArgAsp: 2.312 ± 0.059	2.961ArgGlu: 2.961 ± 0.075	2.95ArgPhe: 2.95 ± 0.071	2.767ArgGly: 2.767 ± 0.062	0.741ArgHis: 0.741 ± 0.034	4.135ArgIle: 4.135 ± 0.085	3.062ArgLys: 3.062 ± 0.067	4.924ArgLeu: 4.924 ± 0.098	1.301ArgMet: 1.301 ± 0.043	1.872ArgAsn: 1.872 ± 0.05	1.601ArgPro: 1.601 ± 0.049	1.418ArgGln: 1.418 ± 0.046	2.673ArgArg: 2.673 ± 0.074	3.168ArgSer: 3.168 ± 0.066	2.623ArgThr: 2.623 ± 0.052	2.749ArgVal: 2.749 ± 0.072	0.471ArgTrp: 0.471 ± 0.029	1.843ArgTyr: 1.843 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	7.223SerAla: 7.223 ± 0.125	0.975SerCys: 0.975 ± 0.034	3.585SerAsp: 3.585 ± 0.074	3.804SerGlu: 3.804 ± 0.074	3.705SerPhe: 3.705 ± 0.083	6.046SerGly: 6.046 ± 0.103	0.914SerHis: 0.914 ± 0.033	3.894SerIle: 3.894 ± 0.083	3.024SerLys: 3.024 ± 0.069	6.523SerLeu: 6.523 ± 0.106	1.311SerMet: 1.311 ± 0.046	1.866SerAsn: 1.866 ± 0.055	2.449SerPro: 2.449 ± 0.058	1.569SerGln: 1.569 ± 0.054	2.99SerArg: 2.99 ± 0.066	4.505SerSer: 4.505 ± 0.098	2.505SerThr: 2.505 ± 0.056	5.662SerVal: 5.662 ± 0.102	0.722SerTrp: 0.722 ± 0.033	2.269SerTyr: 2.269 ± 0.063	0.0SerXaa: 0.0 ± 0.0
Thr	5.93ThrAla: 5.93 ± 0.098	0.557ThrCys: 0.557 ± 0.025	3.396ThrAsp: 3.396 ± 0.075	3.781ThrGlu: 3.781 ± 0.067	2.271ThrPhe: 2.271 ± 0.06	4.683ThrGly: 4.683 ± 0.084	0.896ThrHis: 0.896 ± 0.034	3.18ThrIle: 3.18 ± 0.064	2.864ThrLys: 2.864 ± 0.065	5.363ThrLeu: 5.363 ± 0.089	1.099ThrMet: 1.099 ± 0.039	1.79ThrAsn: 1.79 ± 0.045	2.217ThrPro: 2.217 ± 0.065	1.576ThrGln: 1.576 ± 0.042	1.871ThrArg: 1.871 ± 0.054	2.848ThrSer: 2.848 ± 0.067	2.159ThrThr: 2.159 ± 0.053	5.187ThrVal: 5.187 ± 0.088	0.462ThrTrp: 0.462 ± 0.03	1.708ThrTyr: 1.708 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.169ValAla: 4.169 ± 0.079	1.242ValCys: 1.242 ± 0.047	2.953ValAsp: 2.953 ± 0.064	3.243ValGlu: 3.243 ± 0.068	4.237ValPhe: 4.237 ± 0.081	3.475ValGly: 3.475 ± 0.075	1.226ValHis: 1.226 ± 0.039	4.534ValIle: 4.534 ± 0.091	4.213ValLys: 4.213 ± 0.082	7.56ValLeu: 7.56 ± 0.119	1.583ValMet: 1.583 ± 0.048	2.603ValAsn: 2.603 ± 0.06	3.264ValPro: 3.264 ± 0.069	2.419ValGln: 2.419 ± 0.062	3.616ValArg: 3.616 ± 0.07	5.011ValSer: 5.011 ± 0.091	3.313ValThr: 3.313 ± 0.074	3.793ValVal: 3.793 ± 0.082	0.669ValTrp: 0.669 ± 0.03	2.607ValTyr: 2.607 ± 0.061	0.0ValXaa: 0.0 ± 0.0
Trp	0.685TrpAla: 0.685 ± 0.033	0.155TrpCys: 0.155 ± 0.013	0.527TrpAsp: 0.527 ± 0.028	0.58TrpGlu: 0.58 ± 0.029	0.471TrpPhe: 0.471 ± 0.027	0.585TrpGly: 0.585 ± 0.026	0.171TrpHis: 0.171 ± 0.014	0.605TrpIle: 0.605 ± 0.028	0.748TrpLys: 0.748 ± 0.035	0.957TrpLeu: 0.957 ± 0.035	0.226TrpMet: 0.226 ± 0.017	0.567TrpAsn: 0.567 ± 0.031	0.306TrpPro: 0.306 ± 0.021	0.377TrpGln: 0.377 ± 0.023	0.49TrpArg: 0.49 ± 0.024	0.505TrpSer: 0.505 ± 0.03	0.54TrpThr: 0.54 ± 0.028	0.455TrpVal: 0.455 ± 0.024	0.108TrpTrp: 0.108 ± 0.012	0.397TrpTyr: 0.397 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.39TyrAla: 3.39 ± 0.072	0.454TyrCys: 0.454 ± 0.022	2.12TyrAsp: 2.12 ± 0.053	2.273TyrGlu: 2.273 ± 0.054	1.661TyrPhe: 1.661 ± 0.05	2.54TyrGly: 2.54 ± 0.061	0.465TyrHis: 0.465 ± 0.028	2.325TyrIle: 2.325 ± 0.05	2.213TyrLys: 2.213 ± 0.056	3.01TyrLeu: 3.01 ± 0.068	0.808TyrMet: 0.808 ± 0.035	1.558TyrAsn: 1.558 ± 0.05	1.469TyrPro: 1.469 ± 0.038	0.704TyrGln: 0.704 ± 0.032	2.017TyrArg: 2.017 ± 0.052	2.135TyrSer: 2.135 ± 0.06	2.255TyrThr: 2.255 ± 0.058	2.174TyrVal: 2.174 ± 0.054	0.375TyrTrp: 0.375 ± 0.025	1.376TyrTyr: 1.376 ± 0.046	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2287 proteins (775539 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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