Amino acid dipepetide frequency for Hordeum vulgare alphaendornavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.076AlaAla: 4.076 ± 0.0
1.716AlaCys: 1.716 ± 0.0
3.003AlaAsp: 3.003 ± 0.0
3.218AlaGlu: 3.218 ± 0.0
1.073AlaPhe: 1.073 ± 0.0
4.076AlaGly: 4.076 ± 0.0
1.931AlaHis: 1.931 ± 0.0
3.861AlaIle: 3.861 ± 0.0
3.647AlaLys: 3.647 ± 0.0
5.577AlaLeu: 5.577 ± 0.0
2.574AlaMet: 2.574 ± 0.0
3.432AlaAsn: 3.432 ± 0.0
2.145AlaPro: 2.145 ± 0.0
2.574AlaGln: 2.574 ± 0.0
2.574AlaArg: 2.574 ± 0.0
3.647AlaSer: 3.647 ± 0.0
7.079AlaThr: 7.079 ± 0.0
3.432AlaVal: 3.432 ± 0.0
1.073AlaTrp: 1.073 ± 0.0
0.644AlaTyr: 0.644 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.36CysAla: 2.36 ± 0.0
1.287CysCys: 1.287 ± 0.0
2.145CysAsp: 2.145 ± 0.0
1.287CysGlu: 1.287 ± 0.0
0.215CysPhe: 0.215 ± 0.0
2.789CysGly: 2.789 ± 0.0
1.716CysHis: 1.716 ± 0.0
1.716CysIle: 1.716 ± 0.0
1.073CysLys: 1.073 ± 0.0
0.644CysLeu: 0.644 ± 0.0
0.644CysMet: 0.644 ± 0.0
1.287CysAsn: 1.287 ± 0.0
1.287CysPro: 1.287 ± 0.0
0.644CysGln: 0.644 ± 0.0
0.644CysArg: 0.644 ± 0.0
1.931CysSer: 1.931 ± 0.0
2.574CysThr: 2.574 ± 0.0
1.716CysVal: 1.716 ± 0.0
0.429CysTrp: 0.429 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.145AspAla: 2.145 ± 0.0
0.215AspCys: 0.215 ± 0.0
2.574AspAsp: 2.574 ± 0.0
2.574AspGlu: 2.574 ± 0.0
1.287AspPhe: 1.287 ± 0.0
3.432AspGly: 3.432 ± 0.0
1.931AspHis: 1.931 ± 0.0
3.003AspIle: 3.003 ± 0.0
4.505AspLys: 4.505 ± 0.0
4.076AspLeu: 4.076 ± 0.0
2.145AspMet: 2.145 ± 0.0
2.36AspAsn: 2.36 ± 0.0
2.574AspPro: 2.574 ± 0.0
2.789AspGln: 2.789 ± 0.0
2.36AspArg: 2.36 ± 0.0
2.145AspSer: 2.145 ± 0.0
6.006AspThr: 6.006 ± 0.0
2.789AspVal: 2.789 ± 0.0
1.716AspTrp: 1.716 ± 0.0
1.716AspTyr: 1.716 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.29GluAla: 4.29 ± 0.0
2.36GluCys: 2.36 ± 0.0
3.003GluAsp: 3.003 ± 0.0
3.861GluGlu: 3.861 ± 0.0
1.716GluPhe: 1.716 ± 0.0
2.574GluGly: 2.574 ± 0.0
1.716GluHis: 1.716 ± 0.0
3.647GluIle: 3.647 ± 0.0
1.287GluLys: 1.287 ± 0.0
6.65GluLeu: 6.65 ± 0.0
1.716GluMet: 1.716 ± 0.0
2.574GluAsn: 2.574 ± 0.0
4.076GluPro: 4.076 ± 0.0
4.076GluGln: 4.076 ± 0.0
3.218GluArg: 3.218 ± 0.0
4.076GluSer: 4.076 ± 0.0
1.287GluThr: 1.287 ± 0.0
2.789GluVal: 2.789 ± 0.0
1.716GluTrp: 1.716 ± 0.0
1.931GluTyr: 1.931 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.502PheAla: 1.502 ± 0.0
0.429PheCys: 0.429 ± 0.0
0.858PheAsp: 0.858 ± 0.0
1.716PheGlu: 1.716 ± 0.0
1.073PhePhe: 1.073 ± 0.0
0.858PheGly: 0.858 ± 0.0
0.644PheHis: 0.644 ± 0.0
1.073PheIle: 1.073 ± 0.0
2.574PheLys: 2.574 ± 0.0
1.287PheLeu: 1.287 ± 0.0
0.858PheMet: 0.858 ± 0.0
1.716PheAsn: 1.716 ± 0.0
0.644PhePro: 0.644 ± 0.0
1.073PheGln: 1.073 ± 0.0
0.429PheArg: 0.429 ± 0.0
1.931PheSer: 1.931 ± 0.0
0.429PheThr: 0.429 ± 0.0
2.145PheVal: 2.145 ± 0.0
0.215PheTrp: 0.215 ± 0.0
1.073PheTyr: 1.073 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.789GlyAla: 2.789 ± 0.0
1.287GlyCys: 1.287 ± 0.0
3.218GlyAsp: 3.218 ± 0.0
2.145GlyGlu: 2.145 ± 0.0
0.858GlyPhe: 0.858 ± 0.0
3.218GlyGly: 3.218 ± 0.0
0.858GlyHis: 0.858 ± 0.0
1.502GlyIle: 1.502 ± 0.0
3.003GlyLys: 3.003 ± 0.0
5.148GlyLeu: 5.148 ± 0.0
1.931GlyMet: 1.931 ± 0.0
2.36GlyAsn: 2.36 ± 0.0
2.36GlyPro: 2.36 ± 0.0
3.647GlyGln: 3.647 ± 0.0
3.647GlyArg: 3.647 ± 0.0
2.145GlySer: 2.145 ± 0.0
4.505GlyThr: 4.505 ± 0.0
3.647GlyVal: 3.647 ± 0.0
0.858GlyTrp: 0.858 ± 0.0
1.931GlyTyr: 1.931 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.003HisAla: 3.003 ± 0.0
2.145HisCys: 2.145 ± 0.0
1.287HisAsp: 1.287 ± 0.0
2.145HisGlu: 2.145 ± 0.0
0.644HisPhe: 0.644 ± 0.0
0.858HisGly: 0.858 ± 0.0
1.502HisHis: 1.502 ± 0.0
0.858HisIle: 0.858 ± 0.0
2.789HisLys: 2.789 ± 0.0
3.003HisLeu: 3.003 ± 0.0
1.287HisMet: 1.287 ± 0.0
2.789HisAsn: 2.789 ± 0.0
1.502HisPro: 1.502 ± 0.0
1.287HisGln: 1.287 ± 0.0
1.931HisArg: 1.931 ± 0.0
1.502HisSer: 1.502 ± 0.0
3.432HisThr: 3.432 ± 0.0
3.218HisVal: 3.218 ± 0.0
1.287HisTrp: 1.287 ± 0.0
0.644HisTyr: 0.644 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.574IleAla: 2.574 ± 0.0
0.858IleCys: 0.858 ± 0.0
2.789IleAsp: 2.789 ± 0.0
3.003IleGlu: 3.003 ± 0.0
1.073IlePhe: 1.073 ± 0.0
1.931IleGly: 1.931 ± 0.0
1.287IleHis: 1.287 ± 0.0
3.432IleIle: 3.432 ± 0.0
4.934IleLys: 4.934 ± 0.0
4.505IleLeu: 4.505 ± 0.0
2.789IleMet: 2.789 ± 0.0
4.719IleAsn: 4.719 ± 0.0
1.716IlePro: 1.716 ± 0.0
1.931IleGln: 1.931 ± 0.0
2.145IleArg: 2.145 ± 0.0
4.505IleSer: 4.505 ± 0.0
6.435IleThr: 6.435 ± 0.0
2.789IleVal: 2.789 ± 0.0
0.429IleTrp: 0.429 ± 0.0
1.502IleTyr: 1.502 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.003LysAla: 3.003 ± 0.0
1.073LysCys: 1.073 ± 0.0
1.931LysAsp: 1.931 ± 0.0
4.076LysGlu: 4.076 ± 0.0
1.287LysPhe: 1.287 ± 0.0
2.36LysGly: 2.36 ± 0.0
3.003LysHis: 3.003 ± 0.0
2.574LysIle: 2.574 ± 0.0
1.931LysLys: 1.931 ± 0.0
7.508LysLeu: 7.508 ± 0.0
1.716LysMet: 1.716 ± 0.0
3.218LysAsn: 3.218 ± 0.0
2.36LysPro: 2.36 ± 0.0
1.502LysGln: 1.502 ± 0.0
1.287LysArg: 1.287 ± 0.0
3.432LysSer: 3.432 ± 0.0
5.363LysThr: 5.363 ± 0.0
3.432LysVal: 3.432 ± 0.0
0.644LysTrp: 0.644 ± 0.0
2.574LysTyr: 2.574 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.934LeuAla: 4.934 ± 0.0
2.36LeuCys: 2.36 ± 0.0
4.505LeuAsp: 4.505 ± 0.0
5.363LeuGlu: 5.363 ± 0.0
1.716LeuPhe: 1.716 ± 0.0
3.861LeuGly: 3.861 ± 0.0
2.36LeuHis: 2.36 ± 0.0
4.29LeuIle: 4.29 ± 0.0
5.363LeuLys: 5.363 ± 0.0
8.58LeuLeu: 8.58 ± 0.0
3.647LeuMet: 3.647 ± 0.0
4.934LeuAsn: 4.934 ± 0.0
2.789LeuPro: 2.789 ± 0.0
3.432LeuGln: 3.432 ± 0.0
3.861LeuArg: 3.861 ± 0.0
6.65LeuSer: 6.65 ± 0.0
6.435LeuThr: 6.435 ± 0.0
7.508LeuVal: 7.508 ± 0.0
1.287LeuTrp: 1.287 ± 0.0
1.716LeuTyr: 1.716 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.36MetAla: 2.36 ± 0.0
1.073MetCys: 1.073 ± 0.0
2.145MetAsp: 2.145 ± 0.0
2.574MetGlu: 2.574 ± 0.0
0.429MetPhe: 0.429 ± 0.0
1.287MetGly: 1.287 ± 0.0
1.287MetHis: 1.287 ± 0.0
1.502MetIle: 1.502 ± 0.0
1.502MetLys: 1.502 ± 0.0
3.003MetLeu: 3.003 ± 0.0
1.287MetMet: 1.287 ± 0.0
2.145MetAsn: 2.145 ± 0.0
1.073MetPro: 1.073 ± 0.0
1.716MetGln: 1.716 ± 0.0
1.502MetArg: 1.502 ± 0.0
2.574MetSer: 2.574 ± 0.0
3.218MetThr: 3.218 ± 0.0
2.574MetVal: 2.574 ± 0.0
1.073MetTrp: 1.073 ± 0.0
1.716MetTyr: 1.716 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.931AsnAla: 1.931 ± 0.0
1.073AsnCys: 1.073 ± 0.0
3.861AsnAsp: 3.861 ± 0.0
3.218AsnGlu: 3.218 ± 0.0
1.931AsnPhe: 1.931 ± 0.0
1.502AsnGly: 1.502 ± 0.0
1.931AsnHis: 1.931 ± 0.0
2.789AsnIle: 2.789 ± 0.0
4.29AsnLys: 4.29 ± 0.0
5.363AsnLeu: 5.363 ± 0.0
2.145AsnMet: 2.145 ± 0.0
4.505AsnAsn: 4.505 ± 0.0
1.931AsnPro: 1.931 ± 0.0
2.789AsnGln: 2.789 ± 0.0
3.861AsnArg: 3.861 ± 0.0
2.574AsnSer: 2.574 ± 0.0
5.363AsnThr: 5.363 ± 0.0
3.861AsnVal: 3.861 ± 0.0
0.644AsnTrp: 0.644 ± 0.0
1.931AsnTyr: 1.931 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.36ProAla: 2.36 ± 0.0
1.502ProCys: 1.502 ± 0.0
3.218ProAsp: 3.218 ± 0.0
2.789ProGlu: 2.789 ± 0.0
0.215ProPhe: 0.215 ± 0.0
3.218ProGly: 3.218 ± 0.0
1.931ProHis: 1.931 ± 0.0
3.647ProIle: 3.647 ± 0.0
0.644ProLys: 0.644 ± 0.0
2.36ProLeu: 2.36 ± 0.0
1.931ProMet: 1.931 ± 0.0
2.36ProAsn: 2.36 ± 0.0
2.145ProPro: 2.145 ± 0.0
1.287ProGln: 1.287 ± 0.0
1.287ProArg: 1.287 ± 0.0
2.145ProSer: 2.145 ± 0.0
4.934ProThr: 4.934 ± 0.0
2.36ProVal: 2.36 ± 0.0
1.287ProTrp: 1.287 ± 0.0
0.858ProTyr: 0.858 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.861GlnAla: 3.861 ± 0.0
1.073GlnCys: 1.073 ± 0.0
1.287GlnAsp: 1.287 ± 0.0
3.003GlnGlu: 3.003 ± 0.0
1.502GlnPhe: 1.502 ± 0.0
2.574GlnGly: 2.574 ± 0.0
0.858GlnHis: 0.858 ± 0.0
2.789GlnIle: 2.789 ± 0.0
0.858GlnLys: 0.858 ± 0.0
5.148GlnLeu: 5.148 ± 0.0
1.073GlnMet: 1.073 ± 0.0
0.858GlnAsn: 0.858 ± 0.0
2.36GlnPro: 2.36 ± 0.0
2.789GlnGln: 2.789 ± 0.0
3.003GlnArg: 3.003 ± 0.0
3.647GlnSer: 3.647 ± 0.0
4.29GlnThr: 4.29 ± 0.0
1.931GlnVal: 1.931 ± 0.0
0.858GlnTrp: 0.858 ± 0.0
1.931GlnTyr: 1.931 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.076ArgAla: 4.076 ± 0.0
1.716ArgCys: 1.716 ± 0.0
0.644ArgAsp: 0.644 ± 0.0
2.574ArgGlu: 2.574 ± 0.0
1.287ArgPhe: 1.287 ± 0.0
1.287ArgGly: 1.287 ± 0.0
1.931ArgHis: 1.931 ± 0.0
1.073ArgIle: 1.073 ± 0.0
1.502ArgLys: 1.502 ± 0.0
4.934ArgLeu: 4.934 ± 0.0
1.287ArgMet: 1.287 ± 0.0
1.931ArgAsn: 1.931 ± 0.0
1.716ArgPro: 1.716 ± 0.0
3.432ArgGln: 3.432 ± 0.0
1.931ArgArg: 1.931 ± 0.0
3.647ArgSer: 3.647 ± 0.0
3.432ArgThr: 3.432 ± 0.0
3.861ArgVal: 3.861 ± 0.0
1.073ArgTrp: 1.073 ± 0.0
0.858ArgTyr: 0.858 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.003SerAla: 3.003 ± 0.0
1.073SerCys: 1.073 ± 0.0
4.719SerAsp: 4.719 ± 0.0
4.076SerGlu: 4.076 ± 0.0
1.931SerPhe: 1.931 ± 0.0
3.647SerGly: 3.647 ± 0.0
2.789SerHis: 2.789 ± 0.0
4.719SerIle: 4.719 ± 0.0
2.789SerLys: 2.789 ± 0.0
4.29SerLeu: 4.29 ± 0.0
1.073SerMet: 1.073 ± 0.0
3.218SerAsn: 3.218 ± 0.0
3.218SerPro: 3.218 ± 0.0
1.716SerGln: 1.716 ± 0.0
3.003SerArg: 3.003 ± 0.0
6.006SerSer: 6.006 ± 0.0
6.006SerThr: 6.006 ± 0.0
3.647SerVal: 3.647 ± 0.0
1.931SerTrp: 1.931 ± 0.0
1.931SerTyr: 1.931 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.792ThrAla: 5.792 ± 0.0
0.858ThrCys: 0.858 ± 0.0
3.432ThrAsp: 3.432 ± 0.0
5.792ThrGlu: 5.792 ± 0.0
2.574ThrPhe: 2.574 ± 0.0
5.363ThrGly: 5.363 ± 0.0
4.505ThrHis: 4.505 ± 0.0
5.792ThrIle: 5.792 ± 0.0
4.076ThrLys: 4.076 ± 0.0
5.792ThrLeu: 5.792 ± 0.0
3.861ThrMet: 3.861 ± 0.0
4.719ThrAsn: 4.719 ± 0.0
4.505ThrPro: 4.505 ± 0.0
3.218ThrGln: 3.218 ± 0.0
3.003ThrArg: 3.003 ± 0.0
5.792ThrSer: 5.792 ± 0.0
8.58ThrThr: 8.58 ± 0.0
6.435ThrVal: 6.435 ± 0.0
1.073ThrTrp: 1.073 ± 0.0
2.789ThrTyr: 2.789 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.29ValAla: 4.29 ± 0.0
1.931ValCys: 1.931 ± 0.0
4.076ValAsp: 4.076 ± 0.0
4.29ValGlu: 4.29 ± 0.0
1.073ValPhe: 1.073 ± 0.0
5.577ValGly: 5.577 ± 0.0
2.789ValHis: 2.789 ± 0.0
3.647ValIle: 3.647 ± 0.0
4.934ValLys: 4.934 ± 0.0
3.647ValLeu: 3.647 ± 0.0
2.789ValMet: 2.789 ± 0.0
4.719ValAsn: 4.719 ± 0.0
2.36ValPro: 2.36 ± 0.0
2.36ValGln: 2.36 ± 0.0
2.145ValArg: 2.145 ± 0.0
3.003ValSer: 3.003 ± 0.0
5.148ValThr: 5.148 ± 0.0
6.221ValVal: 6.221 ± 0.0
1.502ValTrp: 1.502 ± 0.0
1.502ValTyr: 1.502 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.287TrpAla: 1.287 ± 0.0
1.073TrpCys: 1.073 ± 0.0
1.073TrpAsp: 1.073 ± 0.0
0.215TrpGlu: 0.215 ± 0.0
0.215TrpPhe: 0.215 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.858TrpHis: 0.858 ± 0.0
1.287TrpIle: 1.287 ± 0.0
1.073TrpLys: 1.073 ± 0.0
2.145TrpLeu: 2.145 ± 0.0
0.644TrpMet: 0.644 ± 0.0
1.287TrpAsn: 1.287 ± 0.0
0.215TrpPro: 0.215 ± 0.0
1.716TrpGln: 1.716 ± 0.0
1.287TrpArg: 1.287 ± 0.0
1.073TrpSer: 1.073 ± 0.0
1.931TrpThr: 1.931 ± 0.0
1.931TrpVal: 1.931 ± 0.0
0.429TrpTrp: 0.429 ± 0.0
0.429TrpTyr: 0.429 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.716TyrAla: 1.716 ± 0.0
1.287TyrCys: 1.287 ± 0.0
2.574TyrAsp: 2.574 ± 0.0
0.644TyrGlu: 0.644 ± 0.0
0.429TyrPhe: 0.429 ± 0.0
0.644TyrGly: 0.644 ± 0.0
1.287TyrHis: 1.287 ± 0.0
2.145TyrIle: 2.145 ± 0.0
1.502TyrLys: 1.502 ± 0.0
1.931TyrLeu: 1.931 ± 0.0
0.429TyrMet: 0.429 ± 0.0
2.36TyrAsn: 2.36 ± 0.0
1.502TyrPro: 1.502 ± 0.0
1.716TyrGln: 1.716 ± 0.0
1.287TyrArg: 1.287 ± 0.0
2.36TyrSer: 2.36 ± 0.0
1.502TyrThr: 1.502 ± 0.0
1.716TyrVal: 1.716 ± 0.0
0.644TyrTrp: 0.644 ± 0.0
1.073TyrTyr: 1.073 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (4663 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski