Amino acid dipepetide frequency for Pseudallescheria apiosperma (Scedosporium apiospermum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.708AlaAla: 9.708 ± 0.075	1.079AlaCys: 1.079 ± 0.019	4.497AlaAsp: 4.497 ± 0.038	5.502AlaGlu: 5.502 ± 0.072	3.212AlaPhe: 3.212 ± 0.028	6.069AlaGly: 6.069 ± 0.04	1.725AlaHis: 1.725 ± 0.02	4.424AlaIle: 4.424 ± 0.034	4.173AlaLys: 4.173 ± 0.041	7.984AlaLeu: 7.984 ± 0.055	1.995AlaMet: 1.995 ± 0.021	2.986AlaAsn: 2.986 ± 0.028	5.006AlaPro: 5.006 ± 0.061	3.248AlaGln: 3.248 ± 0.036	5.012AlaArg: 5.012 ± 0.037	7.134AlaSer: 7.134 ± 0.045	5.364AlaThr: 5.364 ± 0.038	5.688AlaVal: 5.688 ± 0.037	1.176AlaTrp: 1.176 ± 0.018	2.162AlaTyr: 2.162 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.925CysAla: 0.925 ± 0.016	0.227CysCys: 0.227 ± 0.009	0.684CysAsp: 0.684 ± 0.013	0.634CysGlu: 0.634 ± 0.012	0.532CysPhe: 0.532 ± 0.012	0.954CysGly: 0.954 ± 0.018	0.318CysHis: 0.318 ± 0.009	0.704CysIle: 0.704 ± 0.013	0.505CysLys: 0.505 ± 0.011	1.237CysLeu: 1.237 ± 0.019	0.25CysMet: 0.25 ± 0.008	0.415CysAsn: 0.415 ± 0.01	0.675CysPro: 0.675 ± 0.014	0.427CysGln: 0.427 ± 0.009	0.76CysArg: 0.76 ± 0.016	0.849CysSer: 0.849 ± 0.015	0.667CysThr: 0.667 ± 0.013	0.8CysVal: 0.8 ± 0.013	0.2CysTrp: 0.2 ± 0.008	0.345CysTyr: 0.345 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.944AspAla: 4.944 ± 0.034	0.631AspCys: 0.631 ± 0.013	4.548AspAsp: 4.548 ± 0.05	4.711AspGlu: 4.711 ± 0.047	2.327AspPhe: 2.327 ± 0.025	4.36AspGly: 4.36 ± 0.035	1.176AspHis: 1.176 ± 0.019	3.184AspIle: 3.184 ± 0.026	2.435AspLys: 2.435 ± 0.028	5.303AspLeu: 5.303 ± 0.035	1.256AspMet: 1.256 ± 0.017	1.867AspAsn: 1.867 ± 0.021	3.499AspPro: 3.499 ± 0.029	1.743AspGln: 1.743 ± 0.021	3.161AspArg: 3.161 ± 0.04	4.041AspSer: 4.041 ± 0.032	2.886AspThr: 2.886 ± 0.027	3.937AspVal: 3.937 ± 0.03	0.936AspTrp: 0.936 ± 0.014	1.595AspTyr: 1.595 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.774GluAla: 5.774 ± 0.059	0.688GluCys: 0.688 ± 0.012	4.377GluAsp: 4.377 ± 0.045	6.072GluGlu: 6.072 ± 0.097	2.028GluPhe: 2.028 ± 0.02	4.035GluGly: 4.035 ± 0.031	1.285GluHis: 1.285 ± 0.017	3.11GluIle: 3.11 ± 0.031	3.812GluLys: 3.812 ± 0.045	5.346GluLeu: 5.346 ± 0.044	1.444GluMet: 1.444 ± 0.018	2.277GluAsn: 2.277 ± 0.024	3.138GluPro: 3.138 ± 0.081	2.298GluGln: 2.298 ± 0.027	3.986GluArg: 3.986 ± 0.041	4.268GluSer: 4.268 ± 0.042	3.542GluThr: 3.542 ± 0.035	3.887GluVal: 3.887 ± 0.038	0.899GluTrp: 0.899 ± 0.016	1.686GluTyr: 1.686 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.056PheAla: 3.056 ± 0.034	0.563PheCys: 0.563 ± 0.012	2.317PheAsp: 2.317 ± 0.025	2.235PheGlu: 2.235 ± 0.023	1.655PhePhe: 1.655 ± 0.024	2.941PheGly: 2.941 ± 0.033	0.871PheHis: 0.871 ± 0.014	1.86PheIle: 1.86 ± 0.023	1.546PheLys: 1.546 ± 0.024	3.494PheLeu: 3.494 ± 0.036	0.773PheMet: 0.773 ± 0.014	1.402PheAsn: 1.402 ± 0.017	1.99PhePro: 1.99 ± 0.022	1.341PheGln: 1.341 ± 0.017	2.056PheArg: 2.056 ± 0.023	2.94PheSer: 2.94 ± 0.028	2.156PheThr: 2.156 ± 0.028	2.428PheVal: 2.428 ± 0.027	0.629PheTrp: 0.629 ± 0.014	1.135PheTyr: 1.135 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.626GlyAla: 5.626 ± 0.044	0.899GlyCys: 0.899 ± 0.017	3.981GlyAsp: 3.981 ± 0.032	3.959GlyGlu: 3.959 ± 0.034	2.832GlyPhe: 2.832 ± 0.032	6.303GlyGly: 6.303 ± 0.072	1.687GlyHis: 1.687 ± 0.023	3.645GlyIle: 3.645 ± 0.034	3.531GlyLys: 3.531 ± 0.039	6.186GlyLeu: 6.186 ± 0.044	1.544GlyMet: 1.544 ± 0.022	2.629GlyAsn: 2.629 ± 0.032	3.648GlyPro: 3.648 ± 0.038	2.543GlyGln: 2.543 ± 0.031	4.317GlyArg: 4.317 ± 0.033	5.692GlySer: 5.692 ± 0.042	4.03GlyThr: 4.03 ± 0.039	4.579GlyVal: 4.579 ± 0.035	1.186GlyTrp: 1.186 ± 0.017	2.129GlyTyr: 2.129 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.784HisAla: 1.784 ± 0.021	0.311HisCys: 0.311 ± 0.009	1.248HisAsp: 1.248 ± 0.017	1.256HisGlu: 1.256 ± 0.019	0.909HisPhe: 0.909 ± 0.015	1.696HisGly: 1.696 ± 0.02	0.848HisHis: 0.848 ± 0.018	1.204HisIle: 1.204 ± 0.016	0.855HisLys: 0.855 ± 0.014	2.208HisLeu: 2.208 ± 0.022	0.469HisMet: 0.469 ± 0.011	0.768HisAsn: 0.768 ± 0.013	1.642HisPro: 1.642 ± 0.02	0.949HisGln: 0.949 ± 0.02	1.46HisArg: 1.46 ± 0.019	1.629HisSer: 1.629 ± 0.02	1.134HisThr: 1.134 ± 0.016	1.376HisVal: 1.376 ± 0.019	0.336HisTrp: 0.336 ± 0.01	0.674HisTyr: 0.674 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.209IleAla: 4.209 ± 0.038	0.721IleCys: 0.721 ± 0.015	2.959IleAsp: 2.959 ± 0.026	2.949IleGlu: 2.949 ± 0.026	2.018IlePhe: 2.018 ± 0.027	3.217IleGly: 3.217 ± 0.031	1.205IleHis: 1.205 ± 0.018	2.594IleIle: 2.594 ± 0.029	2.187IleLys: 2.187 ± 0.026	4.766IleLeu: 4.766 ± 0.039	0.992IleMet: 0.992 ± 0.015	1.747IleAsn: 1.747 ± 0.02	3.122IlePro: 3.122 ± 0.027	1.857IleGln: 1.857 ± 0.024	2.92IleArg: 2.92 ± 0.028	3.772IleSer: 3.772 ± 0.031	2.823IleThr: 2.823 ± 0.027	3.308IleVal: 3.308 ± 0.03	0.759IleTrp: 0.759 ± 0.018	1.382IleTyr: 1.382 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.393LysAla: 4.393 ± 0.038	0.502LysCys: 0.502 ± 0.012	2.817LysAsp: 2.817 ± 0.03	3.382LysGlu: 3.382 ± 0.042	1.58LysPhe: 1.58 ± 0.019	2.982LysGly: 2.982 ± 0.032	1.032LysHis: 1.032 ± 0.016	2.282LysIle: 2.282 ± 0.026	3.446LysLys: 3.446 ± 0.086	4.089LysLeu: 4.089 ± 0.035	0.973LysMet: 0.973 ± 0.016	1.657LysAsn: 1.657 ± 0.022	2.754LysPro: 2.754 ± 0.029	1.633LysGln: 1.633 ± 0.023	3.29LysArg: 3.29 ± 0.035	3.308LysSer: 3.308 ± 0.028	2.749LysThr: 2.749 ± 0.026	2.875LysVal: 2.875 ± 0.032	0.686LysTrp: 0.686 ± 0.014	1.374LysTyr: 1.374 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	8.258LeuAla: 8.258 ± 0.05	1.19LeuCys: 1.19 ± 0.016	5.409LeuAsp: 5.409 ± 0.04	5.684LeuGlu: 5.684 ± 0.049	3.286LeuPhe: 3.286 ± 0.037	6.214LeuGly: 6.214 ± 0.048	2.12LeuHis: 2.12 ± 0.023	3.98LeuIle: 3.98 ± 0.038	4.186LeuLys: 4.186 ± 0.038	8.403LeuLeu: 8.403 ± 0.067	1.745LeuMet: 1.745 ± 0.022	3.018LeuAsn: 3.018 ± 0.027	5.415LeuPro: 5.415 ± 0.04	3.553LeuGln: 3.553 ± 0.036	5.998LeuArg: 5.998 ± 0.045	7.061LeuSer: 7.061 ± 0.044	4.835LeuThr: 4.835 ± 0.036	5.677LeuVal: 5.677 ± 0.043	1.24LeuTrp: 1.24 ± 0.019	2.362LeuTyr: 2.362 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.223MetAla: 2.223 ± 0.025	0.23MetCys: 0.23 ± 0.008	1.217MetAsp: 1.217 ± 0.018	1.249MetGlu: 1.249 ± 0.018	0.725MetPhe: 0.725 ± 0.012	1.447MetGly: 1.447 ± 0.02	0.444MetHis: 0.444 ± 0.011	0.948MetIle: 0.948 ± 0.016	0.989MetLys: 0.989 ± 0.017	1.777MetLeu: 1.777 ± 0.022	0.542MetMet: 0.542 ± 0.012	0.726MetAsn: 0.726 ± 0.014	1.2MetPro: 1.2 ± 0.017	0.753MetGln: 0.753 ± 0.016	1.255MetArg: 1.255 ± 0.016	1.731MetSer: 1.731 ± 0.021	1.295MetThr: 1.295 ± 0.015	1.301MetVal: 1.301 ± 0.019	0.264MetTrp: 0.264 ± 0.007	0.502MetTyr: 0.502 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.972AsnAla: 2.972 ± 0.029	0.445AsnCys: 0.445 ± 0.01	1.863AsnAsp: 1.863 ± 0.023	1.916AsnGlu: 1.916 ± 0.018	1.368AsnPhe: 1.368 ± 0.02	3.041AsnGly: 3.041 ± 0.031	0.809AsnHis: 0.809 ± 0.014	1.961AsnIle: 1.961 ± 0.022	1.477AsnLys: 1.477 ± 0.018	3.255AsnLeu: 3.255 ± 0.027	0.763AsnMet: 0.763 ± 0.012	1.442AsnAsn: 1.442 ± 0.029	2.509AsnPro: 2.509 ± 0.026	1.249AsnGln: 1.249 ± 0.019	1.937AsnArg: 1.937 ± 0.022	2.553AsnSer: 2.553 ± 0.028	1.954AsnThr: 1.954 ± 0.023	2.255AsnVal: 2.255 ± 0.026	0.545AsnTrp: 0.545 ± 0.011	1.014AsnTyr: 1.014 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.487ProAla: 5.487 ± 0.071	0.515ProCys: 0.515 ± 0.011	3.409ProAsp: 3.409 ± 0.028	4.194ProGlu: 4.194 ± 0.064	2.077ProPhe: 2.077 ± 0.021	4.254ProGly: 4.254 ± 0.045	1.33ProHis: 1.33 ± 0.02	2.59ProIle: 2.59 ± 0.023	2.694ProLys: 2.694 ± 0.033	4.718ProLeu: 4.718 ± 0.035	1.043ProMet: 1.043 ± 0.017	2.219ProAsn: 2.219 ± 0.024	5.537ProPro: 5.537 ± 0.096	2.431ProGln: 2.431 ± 0.041	3.548ProArg: 3.548 ± 0.037	5.81ProSer: 5.81 ± 0.046	4.138ProThr: 4.138 ± 0.041	3.692ProVal: 3.692 ± 0.048	0.762ProTrp: 0.762 ± 0.014	1.453ProTyr: 1.453 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.39GlnAla: 3.39 ± 0.037	0.432GlnCys: 0.432 ± 0.011	1.974GlnAsp: 1.974 ± 0.023	2.278GlnGlu: 2.278 ± 0.023	1.265GlnPhe: 1.265 ± 0.018	2.406GlnGly: 2.406 ± 0.026	0.952GlnHis: 0.952 ± 0.018	1.752GlnIle: 1.752 ± 0.02	1.768GlnLys: 1.768 ± 0.022	3.281GlnLeu: 3.281 ± 0.032	0.805GlnMet: 0.805 ± 0.014	1.366GlnAsn: 1.366 ± 0.02	2.503GlnPro: 2.503 ± 0.045	2.319GlnGln: 2.319 ± 0.055	2.483GlnArg: 2.483 ± 0.026	2.7GlnSer: 2.7 ± 0.027	2.156GlnThr: 2.156 ± 0.023	2.169GlnVal: 2.169 ± 0.024	0.56GlnTrp: 0.56 ± 0.011	1.074GlnTyr: 1.074 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.787ArgAla: 4.787 ± 0.039	0.702ArgCys: 0.702 ± 0.016	3.627ArgAsp: 3.627 ± 0.037	4.032ArgGlu: 4.032 ± 0.039	2.154ArgPhe: 2.154 ± 0.026	3.894ArgGly: 3.894 ± 0.037	1.547ArgHis: 1.547 ± 0.02	3.017ArgIle: 3.017 ± 0.027	3.355ArgLys: 3.355 ± 0.033	5.632ArgLeu: 5.632 ± 0.042	1.248ArgMet: 1.248 ± 0.015	2.279ArgAsn: 2.279 ± 0.025	3.599ArgPro: 3.599 ± 0.034	2.53ArgGln: 2.53 ± 0.027	5.263ArgArg: 5.263 ± 0.055	4.551ArgSer: 4.551 ± 0.041	3.287ArgThr: 3.287 ± 0.028	3.555ArgVal: 3.555 ± 0.032	0.957ArgTrp: 0.957 ± 0.013	1.648ArgTyr: 1.648 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.498SerAla: 6.498 ± 0.046	0.829SerCys: 0.829 ± 0.016	4.124SerAsp: 4.124 ± 0.033	4.103SerGlu: 4.103 ± 0.037	2.935SerPhe: 2.935 ± 0.031	5.628SerGly: 5.628 ± 0.041	1.782SerHis: 1.782 ± 0.022	3.868SerIle: 3.868 ± 0.032	3.455SerLys: 3.455 ± 0.035	6.947SerLeu: 6.947 ± 0.044	1.564SerMet: 1.564 ± 0.02	2.682SerAsn: 2.682 ± 0.028	5.43SerPro: 5.43 ± 0.061	3.02SerGln: 3.02 ± 0.03	4.946SerArg: 4.946 ± 0.04	8.092SerSer: 8.092 ± 0.075	5.206SerThr: 5.206 ± 0.045	4.459SerVal: 4.459 ± 0.035	1.093SerTrp: 1.093 ± 0.017	1.998SerTyr: 1.998 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.201ThrAla: 5.201 ± 0.042	0.732ThrCys: 0.732 ± 0.016	2.82ThrAsp: 2.82 ± 0.026	3.196ThrGlu: 3.196 ± 0.033	2.193ThrPhe: 2.193 ± 0.02	4.197ThrGly: 4.197 ± 0.036	1.202ThrHis: 1.202 ± 0.017	3.073ThrIle: 3.073 ± 0.03	2.51ThrLys: 2.51 ± 0.026	5.267ThrLeu: 5.267 ± 0.04	1.161ThrMet: 1.161 ± 0.018	1.985ThrAsn: 1.985 ± 0.022	4.398ThrPro: 4.398 ± 0.043	1.967ThrGln: 1.967 ± 0.021	3.145ThrArg: 3.145 ± 0.026	4.981ThrSer: 4.981 ± 0.043	4.233ThrThr: 4.233 ± 0.046	3.748ThrVal: 3.748 ± 0.033	0.852ThrTrp: 0.852 ± 0.014	1.563ThrTyr: 1.563 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.594ValAla: 5.594 ± 0.046	0.814ValCys: 0.814 ± 0.013	4.007ValAsp: 4.007 ± 0.032	4.162ValGlu: 4.162 ± 0.052	2.493ValPhe: 2.493 ± 0.03	4.259ValGly: 4.259 ± 0.038	1.365ValHis: 1.365 ± 0.015	3.126ValIle: 3.126 ± 0.032	2.961ValLys: 2.961 ± 0.027	5.732ValLeu: 5.732 ± 0.043	1.323ValMet: 1.323 ± 0.015	2.201ValAsn: 2.201 ± 0.023	3.71ValPro: 3.71 ± 0.035	2.227ValGln: 2.227 ± 0.024	3.533ValArg: 3.533 ± 0.029	4.612ValSer: 4.612 ± 0.036	3.577ValThr: 3.577 ± 0.03	4.602ValVal: 4.602 ± 0.041	0.891ValTrp: 0.891 ± 0.015	1.726ValTyr: 1.726 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.2TrpAla: 1.2 ± 0.019	0.185TrpCys: 0.185 ± 0.007	0.952TrpAsp: 0.952 ± 0.017	0.879TrpGlu: 0.879 ± 0.014	0.561TrpPhe: 0.561 ± 0.012	0.971TrpGly: 0.971 ± 0.017	0.349TrpHis: 0.349 ± 0.01	0.802TrpIle: 0.802 ± 0.013	0.814TrpLys: 0.814 ± 0.014	1.353TrpLeu: 1.353 ± 0.016	0.347TrpMet: 0.347 ± 0.008	0.624TrpAsn: 0.624 ± 0.012	0.638TrpPro: 0.638 ± 0.014	0.534TrpGln: 0.534 ± 0.01	0.946TrpArg: 0.946 ± 0.017	1.005TrpSer: 1.005 ± 0.015	0.884TrpThr: 0.884 ± 0.016	0.941TrpVal: 0.941 ± 0.015	0.265TrpTrp: 0.265 ± 0.009	0.446TrpTyr: 0.446 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.114TyrAla: 2.114 ± 0.024	0.411TyrCys: 0.411 ± 0.01	1.708TyrAsp: 1.708 ± 0.018	1.558TyrGlu: 1.558 ± 0.021	1.238TyrPhe: 1.238 ± 0.018	2.077TyrGly: 2.077 ± 0.027	0.709TyrHis: 0.709 ± 0.014	1.383TyrIle: 1.383 ± 0.021	1.104TyrLys: 1.104 ± 0.016	2.658TyrLeu: 2.658 ± 0.028	0.583TyrMet: 0.583 ± 0.013	1.036TyrAsn: 1.036 ± 0.016	1.488TyrPro: 1.488 ± 0.018	1.014TyrGln: 1.014 ± 0.016	1.648TyrArg: 1.648 ± 0.02	1.927TyrSer: 1.927 ± 0.025	1.509TyrThr: 1.509 ± 0.021	1.639TyrVal: 1.639 ± 0.019	0.462TyrTrp: 0.462 ± 0.011	0.913TyrTyr: 0.913 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8375 proteins (4573252 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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