Amino acid dipepetide frequency for Tomato yellow leaf curl virus (strain Israel) (TYLCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.646AlaAla: 3.646 ± 1.568
0.912AlaCys: 0.912 ± 0.761
0.912AlaAsp: 0.912 ± 0.99
3.646AlaGlu: 3.646 ± 1.408
0.0AlaPhe: 0.0 ± 0.0
0.0AlaGly: 0.0 ± 0.0
1.823AlaHis: 1.823 ± 1.002
1.823AlaIle: 1.823 ± 1.358
3.646AlaLys: 3.646 ± 1.017
5.469AlaLeu: 5.469 ± 2.53
0.912AlaMet: 0.912 ± 0.617
1.823AlaAsn: 1.823 ± 1.019
1.823AlaPro: 1.823 ± 0.923
2.735AlaGln: 2.735 ± 1.151
4.558AlaArg: 4.558 ± 2.389
2.735AlaSer: 2.735 ± 0.806
5.469AlaThr: 5.469 ± 2.467
2.735AlaVal: 2.735 ± 1.396
0.912AlaTrp: 0.912 ± 0.689
0.912AlaTyr: 0.912 ± 0.689
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.823CysCys: 1.823 ± 1.868
0.0CysAsp: 0.0 ± 0.0
0.912CysGlu: 0.912 ± 0.761
0.912CysPhe: 0.912 ± 0.925
1.823CysGly: 1.823 ± 0.955
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.735CysLys: 2.735 ± 1.265
0.912CysLeu: 0.912 ± 0.99
0.912CysMet: 0.912 ± 0.934
1.823CysAsn: 1.823 ± 0.955
1.823CysPro: 1.823 ± 1.868
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.646CysSer: 3.646 ± 2.833
0.912CysThr: 0.912 ± 0.761
1.823CysVal: 1.823 ± 1.521
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.823AspAla: 1.823 ± 1.378
0.912AspCys: 0.912 ± 1.02
2.735AspAsp: 2.735 ± 0.806
2.735AspGlu: 2.735 ± 1.265
2.735AspPhe: 2.735 ± 0.793
1.823AspGly: 1.823 ± 1.378
0.912AspHis: 0.912 ± 0.925
4.558AspIle: 4.558 ± 2.214
1.823AspLys: 1.823 ± 2.039
5.469AspLeu: 5.469 ± 1.63
0.0AspMet: 0.0 ± 0.0
1.823AspAsn: 1.823 ± 1.103
1.823AspPro: 1.823 ± 1.002
0.912AspGln: 0.912 ± 0.99
2.735AspArg: 2.735 ± 1.383
6.381AspSer: 6.381 ± 1.389
0.0AspThr: 0.0 ± 0.0
5.469AspVal: 5.469 ± 1.206
1.823AspTrp: 1.823 ± 0.955
1.823AspTyr: 1.823 ± 1.002
0.0AspXaa: 0.0 ± 0.0
Glu
5.469GluAla: 5.469 ± 1.401
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
5.469GluGlu: 5.469 ± 2.483
2.735GluPhe: 2.735 ± 1.151
4.558GluGly: 4.558 ± 0.986
0.912GluHis: 0.912 ± 0.925
0.912GluIle: 0.912 ± 0.925
2.735GluLys: 2.735 ± 2.067
3.646GluLeu: 3.646 ± 1.408
0.0GluMet: 0.0 ± 0.0
6.381GluAsn: 6.381 ± 1.951
4.558GluPro: 4.558 ± 0.986
1.823GluGln: 1.823 ± 1.521
0.0GluArg: 0.0 ± 0.0
0.912GluSer: 0.912 ± 0.934
4.558GluThr: 4.558 ± 1.412
2.735GluVal: 2.735 ± 1.235
1.823GluTrp: 1.823 ± 0.955
0.912GluTyr: 0.912 ± 0.689
0.0GluXaa: 0.0 ± 0.0
Phe
0.912PheAla: 0.912 ± 0.689
0.912PheCys: 0.912 ± 0.761
2.735PheAsp: 2.735 ± 1.383
0.912PheGlu: 0.912 ± 0.689
2.735PhePhe: 2.735 ± 1.383
1.823PheGly: 1.823 ± 0.784
4.558PheHis: 4.558 ± 0.986
3.646PheIle: 3.646 ± 1.25
3.646PheLys: 3.646 ± 1.066
8.204PheLeu: 8.204 ± 2.043
0.912PheMet: 0.912 ± 0.689
2.735PheAsn: 2.735 ± 0.793
1.823PhePro: 1.823 ± 1.269
1.823PheGln: 1.823 ± 1.103
3.646PheArg: 3.646 ± 2.29
1.823PheSer: 1.823 ± 0.955
0.912PheThr: 0.912 ± 1.02
0.912PheVal: 0.912 ± 0.689
0.0PheTrp: 0.0 ± 0.0
2.735PheTyr: 2.735 ± 1.378
0.0PheXaa: 0.0 ± 0.0
Gly
0.912GlyAla: 0.912 ± 0.689
1.823GlyCys: 1.823 ± 1.103
3.646GlyAsp: 3.646 ± 1.663
1.823GlyGlu: 1.823 ± 0.923
1.823GlyPhe: 1.823 ± 1.358
2.735GlyGly: 2.735 ± 1.265
2.735GlyHis: 2.735 ± 1.174
3.646GlyIle: 3.646 ± 1.25
4.558GlyLys: 4.558 ± 1.989
0.0GlyLeu: 0.0 ± 0.0
0.912GlyMet: 0.912 ± 0.761
3.646GlyAsn: 3.646 ± 1.105
4.558GlyPro: 4.558 ± 1.989
2.735GlyGln: 2.735 ± 0.982
1.823GlyArg: 1.823 ± 0.955
3.646GlySer: 3.646 ± 1.034
1.823GlyThr: 1.823 ± 1.103
2.735GlyVal: 2.735 ± 1.714
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.735HisAla: 2.735 ± 1.681
2.735HisCys: 2.735 ± 2.212
2.735HisAsp: 2.735 ± 2.07
0.912HisGlu: 0.912 ± 0.689
4.558HisPhe: 4.558 ± 1.393
1.823HisGly: 1.823 ± 1.358
1.823HisHis: 1.823 ± 2.039
1.823HisIle: 1.823 ± 1.98
2.735HisLys: 2.735 ± 1.699
2.735HisLeu: 2.735 ± 1.317
0.912HisMet: 0.912 ± 0.99
2.735HisAsn: 2.735 ± 1.34
0.912HisPro: 0.912 ± 0.689
0.912HisGln: 0.912 ± 1.02
1.823HisArg: 1.823 ± 1.103
2.735HisSer: 2.735 ± 1.844
2.735HisThr: 2.735 ± 2.282
3.646HisVal: 3.646 ± 0.987
0.0HisTrp: 0.0 ± 0.0
0.912HisTyr: 0.912 ± 0.689
0.0HisXaa: 0.0 ± 0.0
Ile
0.912IleAla: 0.912 ± 1.02
0.0IleCys: 0.0 ± 0.0
2.735IleAsp: 2.735 ± 2.067
0.912IleGlu: 0.912 ± 0.689
2.735IlePhe: 2.735 ± 1.265
0.912IleGly: 0.912 ± 0.761
0.912IleHis: 0.912 ± 0.925
2.735IleIle: 2.735 ± 1.563
6.381IleLys: 6.381 ± 0.781
2.735IleLeu: 2.735 ± 1.43
1.823IleMet: 1.823 ± 1.478
4.558IleAsn: 4.558 ± 2.406
0.912IlePro: 0.912 ± 0.689
8.204IleGln: 8.204 ± 1.381
6.381IleArg: 6.381 ± 3.177
9.116IleSer: 9.116 ± 1.865
3.646IleThr: 3.646 ± 2.073
2.735IleVal: 2.735 ± 1.383
1.823IleTrp: 1.823 ± 1.85
3.646IleTyr: 3.646 ± 2.09
0.0IleXaa: 0.0 ± 0.0
Lys
4.558LysAla: 4.558 ± 1.918
0.912LysCys: 0.912 ± 0.925
1.823LysAsp: 1.823 ± 1.378
4.558LysGlu: 4.558 ± 2.534
1.823LysPhe: 1.823 ± 1.035
0.912LysGly: 0.912 ± 0.689
2.735LysHis: 2.735 ± 0.982
5.469LysIle: 5.469 ± 1.814
4.558LysLys: 4.558 ± 1.596
0.912LysLeu: 0.912 ± 0.689
0.0LysMet: 0.0 ± 0.0
5.469LysAsn: 5.469 ± 3.202
3.646LysPro: 3.646 ± 0.965
2.735LysGln: 2.735 ± 1.356
4.558LysArg: 4.558 ± 2.947
4.558LysSer: 4.558 ± 1.09
2.735LysThr: 2.735 ± 1.43
6.381LysVal: 6.381 ± 1.451
0.0LysTrp: 0.0 ± 0.0
6.381LysTyr: 6.381 ± 1.737
0.0LysXaa: 0.0 ± 0.0
Leu
0.912LeuAla: 0.912 ± 0.934
1.823LeuCys: 1.823 ± 1.378
6.381LeuAsp: 6.381 ± 2.477
6.381LeuGlu: 6.381 ± 2.165
3.646LeuPhe: 3.646 ± 1.017
4.558LeuGly: 4.558 ± 1.065
2.735LeuHis: 2.735 ± 1.317
4.558LeuIle: 4.558 ± 1.959
6.381LeuLys: 6.381 ± 2.924
2.735LeuLeu: 2.735 ± 1.681
0.912LeuMet: 0.912 ± 0.925
4.558LeuAsn: 4.558 ± 0.986
1.823LeuPro: 1.823 ± 1.497
2.735LeuGln: 2.735 ± 1.174
3.646LeuArg: 3.646 ± 1.547
5.469LeuSer: 5.469 ± 3.28
0.912LeuThr: 0.912 ± 0.689
2.735LeuVal: 2.735 ± 1.383
0.0LeuTrp: 0.0 ± 0.0
3.646LeuTyr: 3.646 ± 1.534
0.0LeuXaa: 0.0 ± 0.0
Met
1.823MetAla: 1.823 ± 1.16
0.912MetCys: 0.912 ± 0.99
3.646MetAsp: 3.646 ± 1.718
0.0MetGlu: 0.0 ± 0.0
2.735MetPhe: 2.735 ± 1.597
2.735MetGly: 2.735 ± 1.235
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.823MetLys: 1.823 ± 1.521
0.912MetLeu: 0.912 ± 0.934
0.0MetMet: 0.0 ± 0.0
0.912MetAsn: 0.912 ± 0.925
1.823MetPro: 1.823 ± 1.019
0.912MetGln: 0.912 ± 1.02
0.912MetArg: 0.912 ± 0.761
1.823MetSer: 1.823 ± 1.16
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.823MetTrp: 1.823 ± 1.002
1.823MetTyr: 1.823 ± 1.521
0.0MetXaa: 0.0 ± 0.0
Asn
1.823AsnAla: 1.823 ± 0.784
1.823AsnCys: 1.823 ± 0.955
2.735AsnAsp: 2.735 ± 1.265
2.735AsnGlu: 2.735 ± 1.356
1.823AsnPhe: 1.823 ± 0.784
3.646AsnGly: 3.646 ± 1.542
6.381AsnHis: 6.381 ± 2.468
5.469AsnIle: 5.469 ± 1.501
2.735AsnLys: 2.735 ± 1.265
3.646AsnLeu: 3.646 ± 1.449
1.823AsnMet: 1.823 ± 1.396
2.735AsnAsn: 2.735 ± 2.201
3.646AsnPro: 3.646 ± 1.044
3.646AsnGln: 3.646 ± 1.88
1.823AsnArg: 1.823 ± 0.955
3.646AsnSer: 3.646 ± 1.431
3.646AsnThr: 3.646 ± 1.345
5.469AsnVal: 5.469 ± 1.927
0.912AsnTrp: 0.912 ± 0.689
1.823AsnTyr: 1.823 ± 1.378
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.823ProCys: 1.823 ± 1.127
1.823ProAsp: 1.823 ± 0.784
1.823ProGlu: 1.823 ± 1.358
1.823ProPhe: 1.823 ± 0.923
1.823ProGly: 1.823 ± 0.784
3.646ProHis: 3.646 ± 2.029
4.558ProIle: 4.558 ± 0.986
5.469ProLys: 5.469 ± 2.302
4.558ProLeu: 4.558 ± 1.393
2.735ProMet: 2.735 ± 1.647
4.558ProAsn: 4.558 ± 1.812
0.912ProPro: 0.912 ± 0.689
3.646ProGln: 3.646 ± 2.504
5.469ProArg: 5.469 ± 1.326
4.558ProSer: 4.558 ± 2.421
5.469ProThr: 5.469 ± 2.86
1.823ProVal: 1.823 ± 1.521
0.912ProTrp: 0.912 ± 0.689
1.823ProTyr: 1.823 ± 1.521
0.0ProXaa: 0.0 ± 0.0
Gln
5.469GlnAla: 5.469 ± 1.743
0.912GlnCys: 0.912 ± 0.689
1.823GlnAsp: 1.823 ± 0.955
2.735GlnGlu: 2.735 ± 0.806
1.823GlnPhe: 1.823 ± 1.378
1.823GlnGly: 1.823 ± 0.784
2.735GlnHis: 2.735 ± 2.363
2.735GlnIle: 2.735 ± 1.34
0.0GlnLys: 0.0 ± 0.0
2.735GlnLeu: 2.735 ± 1.887
1.823GlnMet: 1.823 ± 1.497
2.735GlnAsn: 2.735 ± 1.925
5.469GlnPro: 5.469 ± 3.723
2.735GlnGln: 2.735 ± 1.151
3.646GlnArg: 3.646 ± 1.066
4.558GlnSer: 4.558 ± 0.986
1.823GlnThr: 1.823 ± 1.395
4.558GlnVal: 4.558 ± 1.897
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.646ArgAla: 3.646 ± 1.547
1.823ArgCys: 1.823 ± 1.127
5.469ArgAsp: 5.469 ± 2.467
1.823ArgGlu: 1.823 ± 0.955
5.469ArgPhe: 5.469 ± 1.754
3.646ArgGly: 3.646 ± 1.243
1.823ArgHis: 1.823 ± 1.358
3.646ArgIle: 3.646 ± 1.25
4.558ArgLys: 4.558 ± 1.938
3.646ArgLeu: 3.646 ± 0.965
0.912ArgMet: 0.912 ± 0.761
0.0ArgAsn: 0.0 ± 0.0
7.293ArgPro: 7.293 ± 2.116
1.823ArgGln: 1.823 ± 1.269
5.469ArgArg: 5.469 ± 2.961
4.558ArgSer: 4.558 ± 1.989
4.558ArgThr: 4.558 ± 2.288
2.735ArgVal: 2.735 ± 1.378
0.0ArgTrp: 0.0 ± 0.0
1.823ArgTyr: 1.823 ± 1.313
0.0ArgXaa: 0.0 ± 0.0
Ser
3.646SerAla: 3.646 ± 2.756
0.0SerCys: 0.0 ± 0.0
2.735SerAsp: 2.735 ± 1.983
0.912SerGlu: 0.912 ± 0.689
1.823SerPhe: 1.823 ± 0.955
3.646SerGly: 3.646 ± 1.243
1.823SerHis: 1.823 ± 1.103
10.027SerIle: 10.027 ± 3.234
5.469SerLys: 5.469 ± 1.327
4.558SerLeu: 4.558 ± 1.879
1.823SerMet: 1.823 ± 1.98
7.293SerAsn: 7.293 ± 1.841
9.116SerPro: 9.116 ± 1.815
5.469SerGln: 5.469 ± 2.15
4.558SerArg: 4.558 ± 1.24
8.204SerSer: 8.204 ± 2.59
4.558SerThr: 4.558 ± 1.379
2.735SerVal: 2.735 ± 2.801
0.912SerTrp: 0.912 ± 0.761
2.735SerTyr: 2.735 ± 0.806
0.0SerXaa: 0.0 ± 0.0
Thr
2.735ThrAla: 2.735 ± 1.378
0.0ThrCys: 0.0 ± 0.0
0.912ThrAsp: 0.912 ± 0.689
3.646ThrGlu: 3.646 ± 2.065
1.823ThrPhe: 1.823 ± 1.019
4.558ThrGly: 4.558 ± 1.71
5.469ThrHis: 5.469 ± 2.546
2.735ThrIle: 2.735 ± 1.174
0.912ThrLys: 0.912 ± 0.689
3.646ThrLeu: 3.646 ± 0.987
1.823ThrMet: 1.823 ± 0.784
5.469ThrAsn: 5.469 ± 1.964
1.823ThrPro: 1.823 ± 0.784
1.823ThrGln: 1.823 ± 0.955
1.823ThrArg: 1.823 ± 1.127
2.735ThrSer: 2.735 ± 1.303
1.823ThrThr: 1.823 ± 1.395
1.823ThrVal: 1.823 ± 1.521
1.823ThrTrp: 1.823 ± 1.98
3.646ThrTyr: 3.646 ± 1.268
0.0ThrXaa: 0.0 ± 0.0
Val
0.912ValAla: 0.912 ± 0.689
0.912ValCys: 0.912 ± 0.689
2.735ValAsp: 2.735 ± 1.217
2.735ValGlu: 2.735 ± 1.811
2.735ValPhe: 2.735 ± 1.809
0.912ValGly: 0.912 ± 0.761
0.912ValHis: 0.912 ± 0.934
4.558ValIle: 4.558 ± 1.543
3.646ValLys: 3.646 ± 2.09
3.646ValLeu: 3.646 ± 2.596
2.735ValMet: 2.735 ± 1.563
0.912ValAsn: 0.912 ± 0.99
3.646ValPro: 3.646 ± 1.442
3.646ValGln: 3.646 ± 1.73
4.558ValArg: 4.558 ± 2.373
7.293ValSer: 7.293 ± 1.039
3.646ValThr: 3.646 ± 1.25
1.823ValVal: 1.823 ± 1.002
0.912ValTrp: 0.912 ± 0.761
3.646ValTyr: 3.646 ± 1.88
0.0ValXaa: 0.0 ± 0.0
Trp
1.823TrpAla: 1.823 ± 1.378
0.0TrpCys: 0.0 ± 0.0
0.912TrpAsp: 0.912 ± 0.934
0.912TrpGlu: 0.912 ± 0.925
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.912TrpMet: 0.912 ± 0.761
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.912TrpGln: 0.912 ± 0.689
2.735TrpArg: 2.735 ± 1.303
0.912TrpSer: 0.912 ± 1.02
1.823TrpThr: 1.823 ± 1.035
0.912TrpVal: 0.912 ± 0.689
0.0TrpTrp: 0.0 ± 0.0
1.823TrpTyr: 1.823 ± 1.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.735TyrAla: 2.735 ± 1.265
0.0TyrCys: 0.0 ± 0.0
1.823TyrAsp: 1.823 ± 1.035
4.558TyrGlu: 4.558 ± 1.314
3.646TyrPhe: 3.646 ± 1.25
1.823TyrGly: 1.823 ± 0.784
0.0TyrHis: 0.0 ± 0.0
1.823TyrIle: 1.823 ± 1.378
0.912TyrLys: 0.912 ± 0.925
6.381TyrLeu: 6.381 ± 2.08
1.823TyrMet: 1.823 ± 1.005
1.823TyrAsn: 1.823 ± 1.002
1.823TyrPro: 1.823 ± 1.019
0.912TyrGln: 0.912 ± 0.689
4.558TyrArg: 4.558 ± 2.825
2.735TyrSer: 2.735 ± 1.265
0.0TyrThr: 0.0 ± 0.0
2.735TyrVal: 2.735 ± 1.444
0.0TyrTrp: 0.0 ± 0.0
0.912TyrTyr: 0.912 ± 1.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski