Amino acid dipepetide frequency for Elderberry carlavirus D

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.117AlaAla: 7.117 ± 1.512
1.779AlaCys: 1.779 ± 1.568
2.491AlaAsp: 2.491 ± 0.789
3.559AlaGlu: 3.559 ± 1.396
4.27AlaPhe: 4.27 ± 1.734
4.626AlaGly: 4.626 ± 0.864
1.779AlaHis: 1.779 ± 0.695
4.982AlaIle: 4.982 ± 0.89
4.626AlaLys: 4.626 ± 1.088
9.609AlaLeu: 9.609 ± 3.937
1.779AlaMet: 1.779 ± 0.919
3.559AlaAsn: 3.559 ± 1.99
2.135AlaPro: 2.135 ± 1.633
2.491AlaGln: 2.491 ± 0.668
3.203AlaArg: 3.203 ± 1.178
6.406AlaSer: 6.406 ± 1.278
4.27AlaThr: 4.27 ± 2.625
4.626AlaVal: 4.626 ± 1.191
0.356AlaTrp: 0.356 ± 0.185
2.135AlaTyr: 2.135 ± 0.439
0.0AlaXaa: 0.0 ± 0.0
Cys
3.203CysAla: 3.203 ± 0.621
0.356CysCys: 0.356 ± 0.821
0.0CysAsp: 0.0 ± 0.0
1.068CysGlu: 1.068 ± 0.438
2.491CysPhe: 2.491 ± 0.92
2.135CysGly: 2.135 ± 1.541
0.356CysHis: 0.356 ± 0.185
1.068CysIle: 1.068 ± 1.325
2.491CysLys: 2.491 ± 0.659
3.203CysLeu: 3.203 ± 1.859
0.0CysMet: 0.0 ± 0.0
0.712CysAsn: 0.712 ± 0.61
0.712CysPro: 0.712 ± 0.369
0.712CysGln: 0.712 ± 0.369
1.779CysArg: 1.779 ± 0.556
4.982CysSer: 4.982 ± 1.731
1.068CysThr: 1.068 ± 0.504
4.27CysVal: 4.27 ± 0.92
0.0CysTrp: 0.0 ± 0.0
0.356CysTyr: 0.356 ± 0.185
0.0CysXaa: 0.0 ± 0.0
Asp
3.915AspAla: 3.915 ± 1.702
0.712AspCys: 0.712 ± 0.704
2.135AspAsp: 2.135 ± 0.784
4.982AspGlu: 4.982 ± 1.311
2.491AspPhe: 2.491 ± 0.38
3.203AspGly: 3.203 ± 1.2
0.712AspHis: 0.712 ± 1.642
1.779AspIle: 1.779 ± 0.556
1.068AspLys: 1.068 ± 0.438
4.982AspLeu: 4.982 ± 1.081
0.712AspMet: 0.712 ± 0.369
2.135AspAsn: 2.135 ± 0.735
3.203AspPro: 3.203 ± 0.981
1.779AspGln: 1.779 ± 0.564
1.423AspArg: 1.423 ± 0.962
2.491AspSer: 2.491 ± 1.19
1.779AspThr: 1.779 ± 0.901
2.847AspVal: 2.847 ± 0.923
1.423AspTrp: 1.423 ± 0.584
2.135AspTyr: 2.135 ± 1.049
0.0AspXaa: 0.0 ± 0.0
Glu
5.338GluAla: 5.338 ± 0.614
2.135GluCys: 2.135 ± 1.108
2.135GluAsp: 2.135 ± 0.678
6.05GluGlu: 6.05 ± 1.945
3.559GluPhe: 3.559 ± 1.394
4.626GluGly: 4.626 ± 1.135
1.423GluHis: 1.423 ± 0.937
3.915GluIle: 3.915 ± 1.252
3.559GluLys: 3.559 ± 0.576
7.829GluLeu: 7.829 ± 2.207
1.779GluMet: 1.779 ± 0.912
1.779GluAsn: 1.779 ± 0.564
4.982GluPro: 4.982 ± 1.763
3.203GluGln: 3.203 ± 1.021
3.915GluArg: 3.915 ± 0.797
2.491GluSer: 2.491 ± 1.651
1.068GluThr: 1.068 ± 0.575
5.694GluVal: 5.694 ± 1.165
1.068GluTrp: 1.068 ± 0.62
3.915GluTyr: 3.915 ± 0.797
0.0GluXaa: 0.0 ± 0.0
Phe
4.27PheAla: 4.27 ± 1.39
0.356PheCys: 0.356 ± 0.185
3.559PheAsp: 3.559 ± 1.521
4.982PheGlu: 4.982 ± 1.442
2.491PhePhe: 2.491 ± 0.678
4.27PheGly: 4.27 ± 2.343
0.356PheHis: 0.356 ± 0.185
1.423PheIle: 1.423 ± 0.584
2.491PheLys: 2.491 ± 0.846
6.05PheLeu: 6.05 ± 1.848
1.423PheMet: 1.423 ± 0.688
2.847PheAsn: 2.847 ± 0.923
2.135PhePro: 2.135 ± 0.695
1.068PheGln: 1.068 ± 0.62
1.779PheArg: 1.779 ± 0.923
3.203PheSer: 3.203 ± 0.841
4.27PheThr: 4.27 ± 0.556
4.982PheVal: 4.982 ± 1.372
0.0PheTrp: 0.0 ± 0.0
0.712PheTyr: 0.712 ± 0.61
0.0PheXaa: 0.0 ± 0.0
Gly
5.694GlyAla: 5.694 ± 1.449
2.135GlyCys: 2.135 ± 0.917
3.915GlyAsp: 3.915 ± 1.149
5.694GlyGlu: 5.694 ± 1.129
5.338GlyPhe: 5.338 ± 0.688
3.559GlyGly: 3.559 ± 0.95
0.356GlyHis: 0.356 ± 0.821
2.847GlyIle: 2.847 ± 0.682
3.915GlyLys: 3.915 ± 1.664
7.117GlyLeu: 7.117 ± 1.366
0.712GlyMet: 0.712 ± 0.369
2.135GlyAsn: 2.135 ± 1.108
0.712GlyPro: 0.712 ± 0.369
2.491GlyGln: 2.491 ± 0.723
7.473GlyArg: 7.473 ± 2.95
4.626GlySer: 4.626 ± 1.411
2.491GlyThr: 2.491 ± 0.942
3.203GlyVal: 3.203 ± 1.792
1.423GlyTrp: 1.423 ± 0.47
1.068GlyTyr: 1.068 ± 0.554
0.0GlyXaa: 0.0 ± 0.0
His
1.068HisAla: 1.068 ± 0.438
1.068HisCys: 1.068 ± 0.575
0.712HisAsp: 0.712 ± 0.704
0.356HisGlu: 0.356 ± 0.821
0.712HisPhe: 0.712 ± 0.704
0.712HisGly: 0.712 ± 0.544
0.712HisHis: 0.712 ± 0.627
0.356HisIle: 0.356 ± 0.185
1.423HisLys: 1.423 ± 0.703
1.779HisLeu: 1.779 ± 0.923
0.712HisMet: 0.712 ± 0.369
0.712HisAsn: 0.712 ± 0.704
1.423HisPro: 1.423 ± 0.959
0.0HisGln: 0.0 ± 0.0
1.423HisArg: 1.423 ± 0.739
4.626HisSer: 4.626 ± 1.205
0.712HisThr: 0.712 ± 0.544
2.135HisVal: 2.135 ± 1.661
0.0HisTrp: 0.0 ± 0.0
1.423HisTyr: 1.423 ± 0.47
0.0HisXaa: 0.0 ± 0.0
Ile
4.27IleAla: 4.27 ± 3.467
1.068IleCys: 1.068 ± 0.593
1.423IleAsp: 1.423 ± 0.739
4.982IleGlu: 4.982 ± 1.311
2.847IlePhe: 2.847 ± 0.665
1.068IleGly: 1.068 ± 0.438
0.712IleHis: 0.712 ± 0.544
1.779IleIle: 1.779 ± 0.614
4.27IleLys: 4.27 ± 0.556
2.491IleLeu: 2.491 ± 1.451
1.068IleMet: 1.068 ± 0.554
2.847IleAsn: 2.847 ± 0.735
0.712IlePro: 0.712 ± 0.369
2.135IleGln: 2.135 ± 1.108
3.559IleArg: 3.559 ± 1.492
3.203IleSer: 3.203 ± 1.178
2.491IleThr: 2.491 ± 1.628
2.491IleVal: 2.491 ± 0.767
0.712IleTrp: 0.712 ± 1.273
1.423IleTyr: 1.423 ± 0.739
0.0IleXaa: 0.0 ± 0.0
Lys
2.847LysAla: 2.847 ± 1.358
2.491LysCys: 2.491 ± 0.92
2.491LysAsp: 2.491 ± 1.19
4.982LysGlu: 4.982 ± 1.059
2.847LysPhe: 2.847 ± 0.965
3.559LysGly: 3.559 ± 1.127
2.135LysHis: 2.135 ± 0.695
2.491LysIle: 2.491 ± 1.293
1.779LysLys: 1.779 ± 0.923
7.117LysLeu: 7.117 ± 1.55
0.356LysMet: 0.356 ± 0.541
3.559LysAsn: 3.559 ± 1.351
1.068LysPro: 1.068 ± 0.554
1.068LysGln: 1.068 ± 0.504
3.915LysArg: 3.915 ± 1.394
4.626LysSer: 4.626 ± 1.46
2.491LysThr: 2.491 ± 0.889
2.847LysVal: 2.847 ± 1.009
0.356LysTrp: 0.356 ± 0.582
2.135LysTyr: 2.135 ± 1.108
0.0LysXaa: 0.0 ± 0.0
Leu
7.473LeuAla: 7.473 ± 2.26
3.203LeuCys: 3.203 ± 0.791
4.982LeuAsp: 4.982 ± 1.081
5.338LeuGlu: 5.338 ± 1.82
3.915LeuPhe: 3.915 ± 1.397
7.829LeuGly: 7.829 ± 1.761
3.203LeuHis: 3.203 ± 1.284
4.982LeuIle: 4.982 ± 3.36
8.185LeuLys: 8.185 ± 3.232
12.1LeuLeu: 12.1 ± 1.305
1.423LeuMet: 1.423 ± 0.739
2.847LeuAsn: 2.847 ± 1.07
6.05LeuPro: 6.05 ± 1.104
2.491LeuGln: 2.491 ± 0.38
6.406LeuArg: 6.406 ± 1.051
7.117LeuSer: 7.117 ± 1.321
5.338LeuThr: 5.338 ± 0.703
4.982LeuVal: 4.982 ± 2.38
1.068LeuTrp: 1.068 ± 0.62
2.135LeuTyr: 2.135 ± 1.009
0.0LeuXaa: 0.0 ± 0.0
Met
2.491MetAla: 2.491 ± 1.213
1.779MetCys: 1.779 ± 0.564
0.356MetAsp: 0.356 ± 0.821
1.068MetGlu: 1.068 ± 0.438
0.0MetPhe: 0.0 ± 0.0
1.779MetGly: 1.779 ± 0.564
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.712MetLys: 0.712 ± 0.369
2.135MetLeu: 2.135 ± 1.108
1.068MetMet: 1.068 ± 1.44
0.356MetAsn: 0.356 ± 0.185
2.135MetPro: 2.135 ± 0.638
1.068MetGln: 1.068 ± 0.593
1.779MetArg: 1.779 ± 0.564
1.779MetSer: 1.779 ± 0.923
0.356MetThr: 0.356 ± 0.185
0.356MetVal: 0.356 ± 0.185
0.712MetTrp: 0.712 ± 0.481
0.356MetTyr: 0.356 ± 0.582
0.0MetXaa: 0.0 ± 0.0
Asn
2.491AsnAla: 2.491 ± 0.38
1.068AsnCys: 1.068 ± 1.518
1.423AsnAsp: 1.423 ± 1.35
1.068AsnGlu: 1.068 ± 0.554
3.203AsnPhe: 3.203 ± 1.073
4.27AsnGly: 4.27 ± 1.137
1.779AsnHis: 1.779 ± 0.605
2.135AsnIle: 2.135 ± 1.223
1.068AsnLys: 1.068 ± 0.575
5.694AsnLeu: 5.694 ± 1.363
0.712AsnMet: 0.712 ± 0.61
1.779AsnAsn: 1.779 ± 1.171
2.847AsnPro: 2.847 ± 2.887
1.068AsnGln: 1.068 ± 0.554
4.27AsnArg: 4.27 ± 1.198
1.423AsnSer: 1.423 ± 0.47
1.068AsnThr: 1.068 ± 0.438
3.915AsnVal: 3.915 ± 1.252
0.712AsnTrp: 0.712 ± 0.481
2.491AsnTyr: 2.491 ± 1.213
0.0AsnXaa: 0.0 ± 0.0
Pro
2.135ProAla: 2.135 ± 1.658
1.068ProCys: 1.068 ± 0.593
2.847ProAsp: 2.847 ± 0.406
5.694ProGlu: 5.694 ± 0.812
1.779ProPhe: 1.779 ± 0.923
2.847ProGly: 2.847 ± 1.371
1.068ProHis: 1.068 ± 1.169
1.423ProIle: 1.423 ± 0.739
4.27ProLys: 4.27 ± 1.752
1.779ProLeu: 1.779 ± 0.674
1.068ProMet: 1.068 ± 0.575
2.491ProAsn: 2.491 ± 2.975
2.491ProPro: 2.491 ± 1.683
1.423ProGln: 1.423 ± 0.584
3.915ProArg: 3.915 ± 1.107
2.491ProSer: 2.491 ± 1.056
2.847ProThr: 2.847 ± 0.979
3.203ProVal: 3.203 ± 0.974
0.712ProTrp: 0.712 ± 0.369
0.712ProTyr: 0.712 ± 0.369
0.0ProXaa: 0.0 ± 0.0
Gln
2.847GlnAla: 2.847 ± 0.712
0.712GlnCys: 0.712 ± 0.369
2.135GlnAsp: 2.135 ± 1.108
2.135GlnGlu: 2.135 ± 0.695
0.712GlnPhe: 0.712 ± 0.369
1.068GlnGly: 1.068 ± 0.62
0.712GlnHis: 0.712 ± 0.369
1.423GlnIle: 1.423 ± 0.758
0.356GlnLys: 0.356 ± 0.185
2.491GlnLeu: 2.491 ± 0.846
0.0GlnMet: 0.0 ± 0.0
1.423GlnAsn: 1.423 ± 0.47
2.135GlnPro: 2.135 ± 0.695
1.068GlnGln: 1.068 ± 0.864
1.779GlnArg: 1.779 ± 1.216
3.203GlnSer: 3.203 ± 1.178
1.068GlnThr: 1.068 ± 0.62
1.068GlnVal: 1.068 ± 0.504
0.712GlnTrp: 0.712 ± 0.627
0.712GlnTyr: 0.712 ± 0.704
0.0GlnXaa: 0.0 ± 0.0
Arg
6.05ArgAla: 6.05 ± 1.087
2.135ArgCys: 2.135 ± 0.784
3.203ArgAsp: 3.203 ± 0.823
2.135ArgGlu: 2.135 ± 0.876
5.338ArgPhe: 5.338 ± 1.111
5.338ArgGly: 5.338 ± 1.816
1.068ArgHis: 1.068 ± 0.62
1.423ArgIle: 1.423 ± 0.597
2.491ArgLys: 2.491 ± 0.767
2.847ArgLeu: 2.847 ± 0.406
1.779ArgMet: 1.779 ± 0.564
4.27ArgAsn: 4.27 ± 0.981
3.559ArgPro: 3.559 ± 3.317
0.356ArgGln: 0.356 ± 0.582
4.27ArgArg: 4.27 ± 1.763
4.626ArgSer: 4.626 ± 2.093
4.27ArgThr: 4.27 ± 1.505
3.915ArgVal: 3.915 ± 0.696
0.712ArgTrp: 0.712 ± 0.369
4.626ArgTyr: 4.626 ± 1.253
0.0ArgXaa: 0.0 ± 0.0
Ser
6.05SerAla: 6.05 ± 2.097
1.423SerCys: 1.423 ± 0.739
3.559SerAsp: 3.559 ± 1.351
5.338SerGlu: 5.338 ± 0.775
2.135SerPhe: 2.135 ± 1.108
5.694SerGly: 5.694 ± 0.798
1.779SerHis: 1.779 ± 0.614
3.915SerIle: 3.915 ± 0.589
6.762SerLys: 6.762 ± 1.668
7.473SerLeu: 7.473 ± 2.021
1.779SerMet: 1.779 ± 0.564
2.847SerAsn: 2.847 ± 1.33
3.203SerPro: 3.203 ± 0.753
1.779SerGln: 1.779 ± 0.564
3.559SerArg: 3.559 ± 0.84
6.762SerSer: 6.762 ± 1.768
3.915SerThr: 3.915 ± 1.33
4.982SerVal: 4.982 ± 1.591
0.0SerTrp: 0.0 ± 0.0
0.712SerTyr: 0.712 ± 0.369
0.0SerXaa: 0.0 ± 0.0
Thr
2.491ThrAla: 2.491 ± 1.402
1.779ThrCys: 1.779 ± 1.605
1.423ThrAsp: 1.423 ± 1.35
2.491ThrGlu: 2.491 ± 1.315
4.982ThrPhe: 4.982 ± 1.577
3.915ThrGly: 3.915 ± 1.066
2.135ThrHis: 2.135 ± 1.049
2.491ThrIle: 2.491 ± 1.038
2.847ThrLys: 2.847 ± 1.259
5.338ThrLeu: 5.338 ± 0.837
0.712ThrMet: 0.712 ± 0.369
2.135ThrAsn: 2.135 ± 0.936
1.423ThrPro: 1.423 ± 0.531
0.712ThrGln: 0.712 ± 0.481
3.203ThrArg: 3.203 ± 1.005
3.203ThrSer: 3.203 ± 1.244
1.779ThrThr: 1.779 ± 0.718
2.847ThrVal: 2.847 ± 0.923
0.356ThrTrp: 0.356 ± 0.185
1.068ThrTyr: 1.068 ± 0.554
0.0ThrXaa: 0.0 ± 0.0
Val
4.626ValAla: 4.626 ± 1.616
3.559ValCys: 3.559 ± 0.459
3.915ValAsp: 3.915 ± 0.778
4.626ValGlu: 4.626 ± 0.801
2.847ValPhe: 2.847 ± 1.168
5.338ValGly: 5.338 ± 1.882
1.068ValHis: 1.068 ± 0.575
4.626ValIle: 4.626 ± 0.587
1.423ValLys: 1.423 ± 0.739
5.338ValLeu: 5.338 ± 1.833
1.423ValMet: 1.423 ± 0.47
3.559ValAsn: 3.559 ± 1.763
2.847ValPro: 2.847 ± 2.069
1.779ValGln: 1.779 ± 0.672
3.915ValArg: 3.915 ± 1.566
3.203ValSer: 3.203 ± 1.073
3.559ValThr: 3.559 ± 0.513
4.626ValVal: 4.626 ± 1.721
0.712ValTrp: 0.712 ± 0.481
2.847ValTyr: 2.847 ± 0.923
0.0ValXaa: 0.0 ± 0.0
Trp
0.356TrpAla: 0.356 ± 0.185
1.068TrpCys: 1.068 ± 0.504
1.068TrpAsp: 1.068 ± 0.438
0.356TrpGlu: 0.356 ± 0.185
0.356TrpPhe: 0.356 ± 0.185
0.0TrpGly: 0.0 ± 0.0
0.356TrpHis: 0.356 ± 0.185
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.779TrpLeu: 1.779 ± 0.923
0.0TrpMet: 0.0 ± 0.0
0.712TrpAsn: 0.712 ± 0.481
0.356TrpPro: 0.356 ± 0.821
0.712TrpGln: 0.712 ± 0.481
1.423TrpArg: 1.423 ± 1.295
1.068TrpSer: 1.068 ± 0.62
0.0TrpThr: 0.0 ± 0.0
1.423TrpVal: 1.423 ± 0.924
0.0TrpTrp: 0.0 ± 0.0
0.356TrpTyr: 0.356 ± 0.185
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.068TyrAla: 1.068 ± 0.884
1.068TyrCys: 1.068 ± 0.867
2.135TyrAsp: 2.135 ± 1.108
3.559TyrGlu: 3.559 ± 1.232
0.712TyrPhe: 0.712 ± 0.61
1.068TyrGly: 1.068 ± 0.554
0.356TyrHis: 0.356 ± 0.185
2.491TyrIle: 2.491 ± 0.659
1.423TyrLys: 1.423 ± 0.739
3.915TyrLeu: 3.915 ± 0.964
1.423TyrMet: 1.423 ± 0.47
1.779TyrAsn: 1.779 ± 0.672
2.135TyrPro: 2.135 ± 0.735
0.356TyrGln: 0.356 ± 0.185
1.423TyrArg: 1.423 ± 0.531
2.135TyrSer: 2.135 ± 0.921
2.491TyrThr: 2.491 ± 0.762
1.423TyrVal: 1.423 ± 0.739
0.356TyrTrp: 0.356 ± 0.185
0.712TyrTyr: 0.712 ± 0.61
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2811 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski