Amino acid dipepetide frequency for Rosellinia necatrix quadrivirus 1 (RnQV1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.639AlaAla: 11.639 ± 1.31
3.004AlaCys: 3.004 ± 0.671
7.133AlaAsp: 7.133 ± 0.934
6.383AlaGlu: 6.383 ± 1.001
1.877AlaPhe: 1.877 ± 1.154
8.26AlaGly: 8.26 ± 0.475
3.191AlaHis: 3.191 ± 0.524
5.069AlaIle: 5.069 ± 0.29
4.318AlaLys: 4.318 ± 0.196
9.574AlaLeu: 9.574 ± 1.195
4.505AlaMet: 4.505 ± 0.418
6.007AlaAsn: 6.007 ± 0.281
2.44AlaPro: 2.44 ± 0.734
5.069AlaGln: 5.069 ± 1.6
7.884AlaArg: 7.884 ± 1.12
4.881AlaSer: 4.881 ± 0.836
7.697AlaThr: 7.697 ± 1.394
7.884AlaVal: 7.884 ± 1.117
1.126AlaTrp: 1.126 ± 0.584
3.942AlaTyr: 3.942 ± 0.826
0.0AlaXaa: 0.0 ± 0.0
Cys
2.44CysAla: 2.44 ± 0.875
0.188CysCys: 0.188 ± 0.181
1.314CysAsp: 1.314 ± 0.238
1.877CysGlu: 1.877 ± 0.499
0.563CysPhe: 0.563 ± 0.353
0.751CysGly: 0.751 ± 0.264
0.375CysHis: 0.375 ± 0.199
0.188CysIle: 0.188 ± 0.148
1.502CysLys: 1.502 ± 0.35
0.375CysLeu: 0.375 ± 0.198
0.563CysMet: 0.563 ± 0.445
0.751CysAsn: 0.751 ± 0.289
0.563CysPro: 0.563 ± 0.346
0.188CysGln: 0.188 ± 0.148
0.563CysArg: 0.563 ± 0.277
0.563CysSer: 0.563 ± 0.353
1.126CysThr: 1.126 ± 0.618
1.126CysVal: 1.126 ± 0.141
0.0CysTrp: 0.0 ± 0.0
0.563CysTyr: 0.563 ± 0.543
0.0CysXaa: 0.0 ± 0.0
Asp
6.007AspAla: 6.007 ± 0.447
1.126AspCys: 1.126 ± 0.258
3.191AspAsp: 3.191 ± 0.491
2.628AspGlu: 2.628 ± 1.261
0.939AspPhe: 0.939 ± 0.116
4.693AspGly: 4.693 ± 1.209
0.751AspHis: 0.751 ± 0.288
4.13AspIle: 4.13 ± 0.699
2.253AspLys: 2.253 ± 0.69
5.256AspLeu: 5.256 ± 0.306
2.44AspMet: 2.44 ± 0.85
2.253AspAsn: 2.253 ± 0.283
2.065AspPro: 2.065 ± 0.466
1.502AspGln: 1.502 ± 0.409
3.567AspArg: 3.567 ± 1.045
4.13AspSer: 4.13 ± 0.802
3.754AspThr: 3.754 ± 0.712
4.693AspVal: 4.693 ± 0.763
1.877AspTrp: 1.877 ± 0.438
2.065AspTyr: 2.065 ± 0.447
0.0AspXaa: 0.0 ± 0.0
Glu
6.383GluAla: 6.383 ± 1.082
0.188GluCys: 0.188 ± 0.181
3.567GluAsp: 3.567 ± 1.145
4.13GluGlu: 4.13 ± 0.923
1.314GluPhe: 1.314 ± 0.225
3.754GluGly: 3.754 ± 0.601
1.69GluHis: 1.69 ± 0.203
2.816GluIle: 2.816 ± 0.966
1.314GluLys: 1.314 ± 0.639
5.444GluLeu: 5.444 ± 1.123
2.44GluMet: 2.44 ± 0.896
1.877GluAsn: 1.877 ± 0.277
2.628GluPro: 2.628 ± 0.261
2.628GluGln: 2.628 ± 0.622
4.505GluArg: 4.505 ± 0.748
2.253GluSer: 2.253 ± 0.756
3.191GluThr: 3.191 ± 0.581
4.318GluVal: 4.318 ± 0.533
1.69GluTrp: 1.69 ± 0.223
1.877GluTyr: 1.877 ± 0.277
0.0GluXaa: 0.0 ± 0.0
Phe
3.379PheAla: 3.379 ± 0.302
0.188PheCys: 0.188 ± 0.165
1.69PheAsp: 1.69 ± 0.692
1.126PheGlu: 1.126 ± 0.258
0.375PhePhe: 0.375 ± 0.362
2.253PheGly: 2.253 ± 0.561
0.188PheHis: 0.188 ± 0.148
0.563PheIle: 0.563 ± 0.129
0.375PheLys: 0.375 ± 0.199
2.065PheLeu: 2.065 ± 0.494
0.751PheMet: 0.751 ± 0.486
0.751PheAsn: 0.751 ± 0.486
0.0PhePro: 0.0 ± 0.0
0.939PheGln: 0.939 ± 0.437
1.69PheArg: 1.69 ± 0.485
2.065PheSer: 2.065 ± 0.54
1.877PheThr: 1.877 ± 0.27
0.751PheVal: 0.751 ± 0.274
0.563PheTrp: 0.563 ± 0.295
0.939PheTyr: 0.939 ± 0.348
0.0PheXaa: 0.0 ± 0.0
Gly
4.318GlyAla: 4.318 ± 1.003
1.502GlyCys: 1.502 ± 0.28
5.444GlyAsp: 5.444 ± 0.392
6.57GlyGlu: 6.57 ± 0.615
1.877GlyPhe: 1.877 ± 0.27
6.57GlyGly: 6.57 ± 1.668
3.004GlyHis: 3.004 ± 1.006
3.567GlyIle: 3.567 ± 0.935
2.816GlyLys: 2.816 ± 1.034
7.321GlyLeu: 7.321 ± 1.033
2.253GlyMet: 2.253 ± 0.876
0.939GlyAsn: 0.939 ± 0.207
1.126GlyPro: 1.126 ± 0.435
2.253GlyGln: 2.253 ± 0.15
6.383GlyArg: 6.383 ± 1.39
5.632GlySer: 5.632 ± 0.499
2.816GlyThr: 2.816 ± 0.996
6.383GlyVal: 6.383 ± 0.578
2.253GlyTrp: 2.253 ± 0.492
2.065GlyTyr: 2.065 ± 0.318
0.0GlyXaa: 0.0 ± 0.0
His
2.816HisAla: 2.816 ± 0.692
0.375HisCys: 0.375 ± 0.198
1.502HisAsp: 1.502 ± 0.251
1.126HisGlu: 1.126 ± 0.21
0.939HisPhe: 0.939 ± 0.197
1.877HisGly: 1.877 ± 0.736
1.69HisHis: 1.69 ± 0.351
1.69HisIle: 1.69 ± 0.378
0.751HisLys: 0.751 ± 0.264
1.314HisLeu: 1.314 ± 0.238
0.563HisMet: 0.563 ± 0.178
1.502HisAsn: 1.502 ± 0.544
0.563HisPro: 0.563 ± 0.178
0.563HisGln: 0.563 ± 0.329
1.69HisArg: 1.69 ± 0.373
2.253HisSer: 2.253 ± 0.89
2.44HisThr: 2.44 ± 0.458
2.44HisVal: 2.44 ± 0.797
0.563HisTrp: 0.563 ± 0.258
1.314HisTyr: 1.314 ± 0.45
0.0HisXaa: 0.0 ± 0.0
Ile
6.758IleAla: 6.758 ± 0.526
0.375IleCys: 0.375 ± 0.296
2.065IleAsp: 2.065 ± 0.296
3.004IleGlu: 3.004 ± 0.572
0.563IlePhe: 0.563 ± 0.168
3.004IleGly: 3.004 ± 0.813
0.939IleHis: 0.939 ± 0.389
1.314IleIle: 1.314 ± 0.233
1.502IleLys: 1.502 ± 0.418
2.253IleLeu: 2.253 ± 0.301
1.502IleMet: 1.502 ± 0.473
2.065IleAsn: 2.065 ± 0.805
1.314IlePro: 1.314 ± 0.443
1.502IleGln: 1.502 ± 0.59
2.816IleArg: 2.816 ± 0.558
4.505IleSer: 4.505 ± 0.398
4.505IleThr: 4.505 ± 0.841
3.942IleVal: 3.942 ± 0.517
0.375IleTrp: 0.375 ± 0.198
0.751IleTyr: 0.751 ± 0.24
0.188IleXaa: 0.188 ± 0.148
Lys
2.816LysAla: 2.816 ± 1.11
0.375LysCys: 0.375 ± 0.208
1.877LysAsp: 1.877 ± 0.229
1.314LysGlu: 1.314 ± 0.225
0.751LysPhe: 0.751 ± 0.442
2.065LysGly: 2.065 ± 0.787
0.939LysHis: 0.939 ± 0.41
1.502LysIle: 1.502 ± 0.223
1.126LysLys: 1.126 ± 0.726
4.505LysLeu: 4.505 ± 1.061
1.877LysMet: 1.877 ± 0.356
1.69LysAsn: 1.69 ± 0.734
0.939LysPro: 0.939 ± 0.32
1.877LysGln: 1.877 ± 0.631
2.253LysArg: 2.253 ± 0.655
2.253LysSer: 2.253 ± 0.974
1.877LysThr: 1.877 ± 0.503
3.754LysVal: 3.754 ± 0.479
0.939LysTrp: 0.939 ± 0.47
1.69LysTyr: 1.69 ± 0.775
0.0LysXaa: 0.0 ± 0.0
Leu
10.325LeuAla: 10.325 ± 0.844
1.126LeuCys: 1.126 ± 0.459
3.942LeuAsp: 3.942 ± 0.878
3.567LeuGlu: 3.567 ± 0.62
2.44LeuPhe: 2.44 ± 0.829
7.321LeuGly: 7.321 ± 0.553
1.877LeuHis: 1.877 ± 0.229
3.567LeuIle: 3.567 ± 0.295
3.567LeuLys: 3.567 ± 0.756
6.195LeuLeu: 6.195 ± 1.222
2.628LeuMet: 2.628 ± 0.382
3.004LeuAsn: 3.004 ± 0.646
3.004LeuPro: 3.004 ± 0.619
3.004LeuGln: 3.004 ± 0.785
5.819LeuArg: 5.819 ± 0.864
6.007LeuSer: 6.007 ± 1.412
5.819LeuThr: 5.819 ± 0.833
4.505LeuVal: 4.505 ± 0.633
0.751LeuTrp: 0.751 ± 0.05
2.44LeuTyr: 2.44 ± 0.395
0.0LeuXaa: 0.0 ± 0.0
Met
5.069MetAla: 5.069 ± 1.386
0.375MetCys: 0.375 ± 0.167
2.065MetAsp: 2.065 ± 0.296
1.502MetGlu: 1.502 ± 0.314
0.563MetPhe: 0.563 ± 0.346
2.253MetGly: 2.253 ± 0.425
1.126MetHis: 1.126 ± 0.527
0.939MetIle: 0.939 ± 0.292
1.877MetLys: 1.877 ± 0.528
2.44MetLeu: 2.44 ± 0.565
1.126MetMet: 1.126 ± 0.443
1.69MetAsn: 1.69 ± 0.855
2.628MetPro: 2.628 ± 0.818
1.502MetGln: 1.502 ± 0.314
1.502MetArg: 1.502 ± 0.233
3.191MetSer: 3.191 ± 0.593
2.816MetThr: 2.816 ± 0.427
1.877MetVal: 1.877 ± 0.374
0.375MetTrp: 0.375 ± 0.296
0.563MetTyr: 0.563 ± 0.178
0.0MetXaa: 0.0 ± 0.0
Asn
4.318AsnAla: 4.318 ± 0.646
0.563AsnCys: 0.563 ± 0.329
1.69AsnAsp: 1.69 ± 0.185
1.69AsnGlu: 1.69 ± 0.341
0.939AsnPhe: 0.939 ± 0.47
3.191AsnGly: 3.191 ± 0.295
0.563AsnHis: 0.563 ± 0.353
2.065AsnIle: 2.065 ± 0.9
1.502AsnLys: 1.502 ± 0.1
2.253AsnLeu: 2.253 ± 0.334
1.126AsnMet: 1.126 ± 0.141
1.69AsnAsn: 1.69 ± 0.408
0.939AsnPro: 0.939 ± 0.252
0.939AsnGln: 0.939 ± 0.301
2.816AsnArg: 2.816 ± 0.724
3.191AsnSer: 3.191 ± 0.661
2.065AsnThr: 2.065 ± 0.279
4.881AsnVal: 4.881 ± 0.446
0.751AsnTrp: 0.751 ± 0.264
0.751AsnTyr: 0.751 ± 0.333
0.0AsnXaa: 0.0 ± 0.0
Pro
3.942ProAla: 3.942 ± 0.817
0.188ProCys: 0.188 ± 0.181
2.816ProAsp: 2.816 ± 0.756
1.502ProGlu: 1.502 ± 0.513
0.751ProPhe: 0.751 ± 0.636
2.253ProGly: 2.253 ± 0.614
0.939ProHis: 0.939 ± 0.439
0.751ProIle: 0.751 ± 0.264
1.314ProLys: 1.314 ± 0.359
2.816ProLeu: 2.816 ± 0.359
2.065ProMet: 2.065 ± 0.555
0.751ProAsn: 0.751 ± 0.193
1.502ProPro: 1.502 ± 0.1
1.502ProGln: 1.502 ± 0.371
1.502ProArg: 1.502 ± 0.813
1.69ProSer: 1.69 ± 0.295
2.628ProThr: 2.628 ± 0.633
2.065ProVal: 2.065 ± 0.325
0.375ProTrp: 0.375 ± 0.198
1.502ProTyr: 1.502 ± 0.144
0.0ProXaa: 0.0 ± 0.0
Gln
5.632GlnAla: 5.632 ± 1.211
0.563GlnCys: 0.563 ± 0.168
1.126GlnAsp: 1.126 ± 0.261
2.44GlnGlu: 2.44 ± 0.715
1.502GlnPhe: 1.502 ± 0.364
2.065GlnGly: 2.065 ± 0.9
1.126GlnHis: 1.126 ± 0.494
0.939GlnIle: 0.939 ± 0.497
0.939GlnLys: 0.939 ± 0.207
3.191GlnLeu: 3.191 ± 0.675
1.314GlnMet: 1.314 ± 0.571
2.065GlnAsn: 2.065 ± 0.529
0.563GlnPro: 0.563 ± 0.129
1.314GlnGln: 1.314 ± 0.191
1.69GlnArg: 1.69 ± 0.1
1.69GlnSer: 1.69 ± 0.585
2.44GlnThr: 2.44 ± 1.024
2.44GlnVal: 2.44 ± 0.524
0.751GlnTrp: 0.751 ± 0.24
1.126GlnTyr: 1.126 ± 0.151
0.0GlnXaa: 0.0 ± 0.0
Arg
7.884ArgAla: 7.884 ± 1.175
0.563ArgCys: 0.563 ± 0.258
4.505ArgAsp: 4.505 ± 0.351
4.693ArgGlu: 4.693 ± 0.263
1.69ArgPhe: 1.69 ± 0.366
3.942ArgGly: 3.942 ± 0.415
2.253ArgHis: 2.253 ± 0.528
3.942ArgIle: 3.942 ± 0.575
1.314ArgLys: 1.314 ± 0.191
5.256ArgLeu: 5.256 ± 0.382
2.628ArgMet: 2.628 ± 0.91
1.126ArgAsn: 1.126 ± 0.443
3.004ArgPro: 3.004 ± 0.633
2.44ArgGln: 2.44 ± 0.353
4.318ArgArg: 4.318 ± 1.296
5.444ArgSer: 5.444 ± 0.481
2.628ArgThr: 2.628 ± 0.398
3.942ArgVal: 3.942 ± 0.539
1.126ArgTrp: 1.126 ± 0.437
0.939ArgTyr: 0.939 ± 0.197
0.0ArgXaa: 0.0 ± 0.0
Ser
7.697SerAla: 7.697 ± 1.665
1.877SerCys: 1.877 ± 0.702
3.004SerAsp: 3.004 ± 0.632
4.881SerGlu: 4.881 ± 0.795
1.502SerPhe: 1.502 ± 0.144
6.946SerGly: 6.946 ± 0.576
1.502SerHis: 1.502 ± 0.35
3.379SerIle: 3.379 ± 0.582
2.253SerLys: 2.253 ± 0.405
4.13SerLeu: 4.13 ± 0.891
1.502SerMet: 1.502 ± 0.144
2.065SerAsn: 2.065 ± 0.418
1.69SerPro: 1.69 ± 0.621
1.502SerGln: 1.502 ± 0.348
4.13SerArg: 4.13 ± 0.967
5.444SerSer: 5.444 ± 1.424
7.133SerThr: 7.133 ± 1.069
4.881SerVal: 4.881 ± 0.689
1.877SerTrp: 1.877 ± 0.504
0.939SerTyr: 0.939 ± 0.348
0.0SerXaa: 0.0 ± 0.0
Thr
6.57ThrAla: 6.57 ± 1.345
0.751ThrCys: 0.751 ± 0.411
4.693ThrAsp: 4.693 ± 0.588
3.942ThrGlu: 3.942 ± 0.811
1.126ThrPhe: 1.126 ± 0.261
6.383ThrGly: 6.383 ± 1.727
0.563ThrHis: 0.563 ± 0.477
4.505ThrIle: 4.505 ± 0.809
2.44ThrLys: 2.44 ± 0.691
5.069ThrLeu: 5.069 ± 0.461
1.877ThrMet: 1.877 ± 0.15
1.502ThrAsn: 1.502 ± 0.508
2.816ThrPro: 2.816 ± 0.563
2.44ThrGln: 2.44 ± 0.476
4.318ThrArg: 4.318 ± 0.693
3.942ThrSer: 3.942 ± 0.573
6.383ThrThr: 6.383 ± 1.609
6.195ThrVal: 6.195 ± 1.026
1.314ThrTrp: 1.314 ± 0.312
2.816ThrTyr: 2.816 ± 0.585
0.0ThrXaa: 0.0 ± 0.0
Val
8.072ValAla: 8.072 ± 0.342
1.314ValCys: 1.314 ± 0.559
3.379ValAsp: 3.379 ± 0.409
3.004ValGlu: 3.004 ± 0.859
1.69ValPhe: 1.69 ± 0.296
3.942ValGly: 3.942 ± 0.619
3.567ValHis: 3.567 ± 0.757
1.877ValIle: 1.877 ± 0.15
3.191ValLys: 3.191 ± 0.565
5.632ValLeu: 5.632 ± 2.09
2.816ValMet: 2.816 ± 0.451
3.942ValAsn: 3.942 ± 1.08
3.004ValPro: 3.004 ± 0.824
2.628ValGln: 2.628 ± 0.859
3.754ValArg: 3.754 ± 0.686
5.444ValSer: 5.444 ± 1.257
5.632ValThr: 5.632 ± 0.687
6.383ValVal: 6.383 ± 0.427
0.939ValTrp: 0.939 ± 0.207
3.567ValTyr: 3.567 ± 0.555
0.0ValXaa: 0.0 ± 0.0
Trp
2.628TrpAla: 2.628 ± 1.215
0.375TrpCys: 0.375 ± 0.198
0.751TrpAsp: 0.751 ± 0.193
0.939TrpGlu: 0.939 ± 0.434
0.751TrpPhe: 0.751 ± 0.411
1.314TrpGly: 1.314 ± 0.443
0.375TrpHis: 0.375 ± 0.198
0.939TrpIle: 0.939 ± 0.47
0.563TrpLys: 0.563 ± 0.315
3.004TrpLeu: 3.004 ± 0.604
0.563TrpMet: 0.563 ± 0.259
0.939TrpAsn: 0.939 ± 0.338
0.939TrpPro: 0.939 ± 0.454
0.375TrpGln: 0.375 ± 0.296
1.126TrpArg: 1.126 ± 0.375
1.126TrpSer: 1.126 ± 0.692
0.375TrpThr: 0.375 ± 0.195
0.188TrpVal: 0.188 ± 0.159
0.0TrpTrp: 0.0 ± 0.0
0.563TrpTyr: 0.563 ± 0.258
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.191TyrAla: 3.191 ± 0.877
0.563TyrCys: 0.563 ± 0.178
3.379TyrAsp: 3.379 ± 0.2
1.69TyrGlu: 1.69 ± 0.378
0.375TyrPhe: 0.375 ± 0.33
2.253TyrGly: 2.253 ± 0.519
1.314TyrHis: 1.314 ± 0.319
1.502TyrIle: 1.502 ± 0.307
1.502TyrLys: 1.502 ± 0.651
2.816TyrLeu: 2.816 ± 0.469
0.751TyrMet: 0.751 ± 0.274
1.314TyrAsn: 1.314 ± 0.278
1.126TyrPro: 1.126 ± 0.669
0.751TyrGln: 0.751 ± 0.24
1.314TyrArg: 1.314 ± 0.799
2.628TyrSer: 2.628 ± 0.785
2.44TyrThr: 2.44 ± 0.674
1.126TyrVal: 1.126 ± 0.375
0.375TyrTrp: 0.375 ± 0.296
2.065TyrTyr: 2.065 ± 0.384
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.188XaaAsp: 0.188 ± 0.148
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (5328 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski