Amino acid dipepetide frequency for Bhanja virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.582AlaAla: 4.582 ± 3.267
1.887AlaCys: 1.887 ± 0.504
2.965AlaAsp: 2.965 ± 0.162
2.965AlaGlu: 2.965 ± 0.162
2.426AlaPhe: 2.426 ± 1.19
2.156AlaGly: 2.156 ± 0.675
0.27AlaHis: 0.27 ± 0.246
3.504AlaIle: 3.504 ± 0.541
3.774AlaLys: 3.774 ± 1.593
7.817AlaLeu: 7.817 ± 2.356
1.348AlaMet: 1.348 ± 1.401
2.426AlaAsn: 2.426 ± 0.867
2.156AlaPro: 2.156 ± 0.361
1.887AlaGln: 1.887 ± 0.269
3.774AlaArg: 3.774 ± 0.848
5.391AlaSer: 5.391 ± 0.366
2.695AlaThr: 2.695 ± 0.693
2.965AlaVal: 2.965 ± 0.501
1.078AlaTrp: 1.078 ± 0.368
1.617AlaTyr: 1.617 ± 0.861
0.0AlaXaa: 0.0 ± 0.0
Cys
1.887CysAla: 1.887 ± 0.523
0.809CysCys: 0.809 ± 0.44
1.617CysAsp: 1.617 ± 0.878
1.078CysGlu: 1.078 ± 0.324
0.809CysPhe: 0.809 ± 0.208
2.156CysGly: 2.156 ± 1.068
0.27CysHis: 0.27 ± 0.153
1.887CysIle: 1.887 ± 0.716
2.426CysLys: 2.426 ± 0.667
2.965CysLeu: 2.965 ± 0.75
1.617CysMet: 1.617 ± 0.607
0.0CysAsn: 0.0 ± 0.0
0.539CysPro: 0.539 ± 0.451
0.539CysGln: 0.539 ± 0.169
1.617CysArg: 1.617 ± 0.506
3.774CysSer: 3.774 ± 2.049
1.617CysThr: 1.617 ± 1.121
1.887CysVal: 1.887 ± 1.025
0.0CysTrp: 0.0 ± 0.0
1.078CysTyr: 1.078 ± 0.809
0.0CysXaa: 0.0 ± 0.0
Asp
2.156AspAla: 2.156 ± 0.767
1.348AspCys: 1.348 ± 0.347
4.043AspAsp: 4.043 ± 1.105
7.008AspGlu: 7.008 ± 0.491
2.426AspPhe: 2.426 ± 0.624
4.582AspGly: 4.582 ± 0.854
0.539AspHis: 0.539 ± 0.306
4.043AspIle: 4.043 ± 1.636
1.617AspLys: 1.617 ± 0.787
4.582AspLeu: 4.582 ± 0.914
0.809AspMet: 0.809 ± 0.393
2.156AspAsn: 2.156 ± 0.445
2.156AspPro: 2.156 ± 0.606
1.348AspGln: 1.348 ± 0.462
3.235AspArg: 3.235 ± 0.578
4.043AspSer: 4.043 ± 0.738
3.774AspThr: 3.774 ± 1.045
4.043AspVal: 4.043 ± 0.549
0.539AspTrp: 0.539 ± 0.451
1.617AspTyr: 1.617 ± 0.607
0.0AspXaa: 0.0 ± 0.0
Glu
5.121GluAla: 5.121 ± 1.289
1.887GluCys: 1.887 ± 0.716
5.391GluAsp: 5.391 ± 1.429
6.199GluGlu: 6.199 ± 1.598
2.426GluPhe: 2.426 ± 0.465
4.313GluGly: 4.313 ± 0.889
0.809GluHis: 0.809 ± 0.208
2.965GluIle: 2.965 ± 0.733
4.313GluLys: 4.313 ± 1.212
7.817GluLeu: 7.817 ± 0.539
2.426GluMet: 2.426 ± 0.532
2.965GluAsn: 2.965 ± 0.733
1.078GluPro: 1.078 ± 0.324
2.965GluGln: 2.965 ± 0.526
3.774GluArg: 3.774 ± 0.996
5.391GluSer: 5.391 ± 1.383
3.235GluThr: 3.235 ± 1.66
5.66GluVal: 5.66 ± 1.123
0.27GluTrp: 0.27 ± 0.153
1.078GluTyr: 1.078 ± 0.512
0.0GluXaa: 0.0 ± 0.0
Phe
4.043PheAla: 4.043 ± 1.037
1.348PheCys: 1.348 ± 0.552
1.348PheAsp: 1.348 ± 1.087
1.617PheGlu: 1.617 ± 0.397
2.156PhePhe: 2.156 ± 0.546
2.156PheGly: 2.156 ± 0.606
1.348PheHis: 1.348 ± 0.376
2.426PheIle: 2.426 ± 0.882
3.774PheLys: 3.774 ± 1.244
4.582PheLeu: 4.582 ± 1.315
1.078PheMet: 1.078 ± 0.633
2.426PheAsn: 2.426 ± 0.408
1.887PhePro: 1.887 ± 1.071
0.809PheGln: 0.809 ± 0.459
2.965PheArg: 2.965 ± 0.718
2.965PheSer: 2.965 ± 0.844
3.235PheThr: 3.235 ± 0.163
1.348PheVal: 1.348 ± 0.347
0.0PheTrp: 0.0 ± 0.0
1.617PheTyr: 1.617 ± 1.002
0.0PheXaa: 0.0 ± 0.0
Gly
3.504GlyAla: 3.504 ± 1.106
3.235GlyCys: 3.235 ± 0.87
4.043GlyAsp: 4.043 ± 0.693
4.852GlyGlu: 4.852 ± 0.381
4.043GlyPhe: 4.043 ± 0.218
3.504GlyGly: 3.504 ± 0.598
2.426GlyHis: 2.426 ± 0.437
4.852GlyIle: 4.852 ± 0.666
3.504GlyLys: 3.504 ± 1.466
4.852GlyLeu: 4.852 ± 0.821
1.078GlyMet: 1.078 ± 0.305
2.426GlyAsn: 2.426 ± 0.303
2.695GlyPro: 2.695 ± 0.27
1.887GlyGln: 1.887 ± 0.489
2.965GlyArg: 2.965 ± 0.643
6.199GlySer: 6.199 ± 1.541
2.695GlyThr: 2.695 ± 0.607
4.043GlyVal: 4.043 ± 1.1
1.348GlyTrp: 1.348 ± 0.628
0.539GlyTyr: 0.539 ± 0.451
0.0GlyXaa: 0.0 ± 0.0
His
2.156HisAla: 2.156 ± 0.445
0.27HisCys: 0.27 ± 0.246
1.078HisAsp: 1.078 ± 0.324
1.348HisGlu: 1.348 ± 0.765
0.27HisPhe: 0.27 ± 0.153
1.617HisGly: 1.617 ± 0.289
0.0HisHis: 0.0 ± 0.0
0.27HisIle: 0.27 ± 0.153
0.809HisLys: 0.809 ± 0.393
2.156HisLeu: 2.156 ± 0.648
0.539HisMet: 0.539 ± 0.451
0.539HisAsn: 0.539 ± 0.169
0.809HisPro: 0.809 ± 0.737
1.348HisGln: 1.348 ± 0.462
1.348HisArg: 1.348 ± 0.765
0.27HisSer: 0.27 ± 0.246
0.539HisThr: 0.539 ± 0.451
1.348HisVal: 1.348 ± 0.462
0.539HisTrp: 0.539 ± 0.169
1.617HisTyr: 1.617 ± 0.506
0.0HisXaa: 0.0 ± 0.0
Ile
2.156IleAla: 2.156 ± 0.329
1.617IleCys: 1.617 ± 0.63
3.774IleAsp: 3.774 ± 0.685
5.121IleGlu: 5.121 ± 1.157
2.426IlePhe: 2.426 ± 0.72
2.965IleGly: 2.965 ± 0.762
0.809IleHis: 0.809 ± 0.737
3.504IleIle: 3.504 ± 0.698
4.852IleLys: 4.852 ± 1.336
7.278IleLeu: 7.278 ± 0.6
0.539IleMet: 0.539 ± 0.169
3.774IleAsn: 3.774 ± 1.097
1.887IlePro: 1.887 ± 0.489
2.965IleGln: 2.965 ± 1.436
4.582IleArg: 4.582 ± 1.983
7.008IleSer: 7.008 ± 0.97
3.774IleThr: 3.774 ± 0.851
3.235IleVal: 3.235 ± 1.744
0.27IleTrp: 0.27 ± 0.153
1.078IleTyr: 1.078 ± 0.612
0.0IleXaa: 0.0 ± 0.0
Lys
4.043LysAla: 4.043 ± 2.315
0.809LysCys: 0.809 ± 0.737
3.504LysAsp: 3.504 ± 1.273
7.008LysGlu: 7.008 ± 1.195
1.348LysPhe: 1.348 ± 0.462
4.313LysGly: 4.313 ± 0.846
1.078LysHis: 1.078 ± 0.324
3.235LysIle: 3.235 ± 0.699
4.582LysLys: 4.582 ± 1.037
4.582LysLeu: 4.582 ± 1.389
2.695LysMet: 2.695 ± 1.279
3.504LysAsn: 3.504 ± 1.308
1.887LysPro: 1.887 ± 1.025
1.887LysGln: 1.887 ± 0.489
3.235LysArg: 3.235 ± 1.214
4.852LysSer: 4.852 ± 0.534
3.774LysThr: 3.774 ± 0.851
4.852LysVal: 4.852 ± 1.287
1.348LysTrp: 1.348 ± 0.877
1.348LysTyr: 1.348 ± 0.565
0.0LysXaa: 0.0 ± 0.0
Leu
6.199LeuAla: 6.199 ± 0.99
2.156LeuCys: 2.156 ± 0.379
6.199LeuAsp: 6.199 ± 1.177
7.278LeuGlu: 7.278 ± 2.271
3.774LeuPhe: 3.774 ± 0.693
6.199LeuGly: 6.199 ± 1.128
1.348LeuHis: 1.348 ± 0.462
7.547LeuIle: 7.547 ± 0.191
7.278LeuLys: 7.278 ± 1.595
7.817LeuLeu: 7.817 ± 1.984
2.695LeuMet: 2.695 ± 0.437
3.504LeuAsn: 3.504 ± 0.497
3.504LeuPro: 3.504 ± 1.464
4.313LeuGln: 4.313 ± 1.107
4.852LeuArg: 4.852 ± 1.176
10.243LeuSer: 10.243 ± 1.32
5.391LeuThr: 5.391 ± 1.637
6.199LeuVal: 6.199 ± 1.736
1.617LeuTrp: 1.617 ± 0.397
1.887LeuTyr: 1.887 ± 0.732
0.0LeuXaa: 0.0 ± 0.0
Met
1.617MetAla: 1.617 ± 1.304
0.809MetCys: 0.809 ± 0.459
0.809MetAsp: 0.809 ± 0.458
2.426MetGlu: 2.426 ± 0.624
0.27MetPhe: 0.27 ± 0.246
2.156MetGly: 2.156 ± 0.872
0.809MetHis: 0.809 ± 0.208
2.156MetIle: 2.156 ± 0.648
1.887MetLys: 1.887 ± 0.464
3.504MetLeu: 3.504 ± 0.721
1.078MetMet: 1.078 ± 0.324
0.539MetAsn: 0.539 ± 0.435
0.27MetPro: 0.27 ± 0.153
0.27MetGln: 0.27 ± 0.153
0.809MetArg: 0.809 ± 0.208
2.426MetSer: 2.426 ± 0.958
2.695MetThr: 2.695 ± 1.084
1.617MetVal: 1.617 ± 0.997
0.0MetTrp: 0.0 ± 0.0
0.27MetTyr: 0.27 ± 0.153
0.0MetXaa: 0.0 ± 0.0
Asn
1.617AsnAla: 1.617 ± 0.966
1.348AsnCys: 1.348 ± 1.229
1.617AsnAsp: 1.617 ± 0.607
1.617AsnGlu: 1.617 ± 0.397
2.426AsnPhe: 2.426 ± 0.783
1.348AsnGly: 1.348 ± 0.566
0.0AsnHis: 0.0 ± 0.0
2.426AsnIle: 2.426 ± 0.845
1.348AsnLys: 1.348 ± 0.852
4.313AsnLeu: 4.313 ± 1.139
1.078AsnMet: 1.078 ± 0.35
0.809AsnAsn: 0.809 ± 0.393
3.504AsnPro: 3.504 ± 0.698
2.426AsnGln: 2.426 ± 0.624
1.348AsnArg: 1.348 ± 0.822
2.965AsnSer: 2.965 ± 0.815
0.539AsnThr: 0.539 ± 0.451
2.695AsnVal: 2.695 ± 0.437
1.617AsnTrp: 1.617 ± 0.506
1.348AsnTyr: 1.348 ± 0.602
0.0AsnXaa: 0.0 ± 0.0
Pro
1.078ProAla: 1.078 ± 0.368
0.539ProCys: 0.539 ± 0.492
3.235ProAsp: 3.235 ± 0.794
2.426ProGlu: 2.426 ± 0.845
1.887ProPhe: 1.887 ± 0.269
2.695ProGly: 2.695 ± 0.437
0.539ProHis: 0.539 ± 0.306
2.695ProIle: 2.695 ± 1.483
2.426ProLys: 2.426 ± 0.544
3.235ProLeu: 3.235 ± 0.558
1.078ProMet: 1.078 ± 1.071
0.809ProAsn: 0.809 ± 0.208
1.887ProPro: 1.887 ± 0.767
1.887ProGln: 1.887 ± 0.269
2.156ProArg: 2.156 ± 1.215
1.887ProSer: 1.887 ± 0.716
2.156ProThr: 2.156 ± 1.952
2.965ProVal: 2.965 ± 0.576
0.809ProTrp: 0.809 ± 0.459
0.809ProTyr: 0.809 ± 0.393
0.0ProXaa: 0.0 ± 0.0
Gln
1.887GlnAla: 1.887 ± 0.978
1.348GlnCys: 1.348 ± 0.877
1.887GlnAsp: 1.887 ± 1.071
3.504GlnGlu: 3.504 ± 0.537
1.887GlnPhe: 1.887 ± 0.463
2.965GlnGly: 2.965 ± 0.688
1.078GlnHis: 1.078 ± 0.337
2.965GlnIle: 2.965 ± 0.526
2.426GlnLys: 2.426 ± 0.783
2.426GlnLeu: 2.426 ± 0.802
1.617GlnMet: 1.617 ± 0.918
2.156GlnAsn: 2.156 ± 0.379
0.539GlnPro: 0.539 ± 0.492
0.539GlnGln: 0.539 ± 0.492
1.887GlnArg: 1.887 ± 0.418
1.617GlnSer: 1.617 ± 0.607
1.887GlnThr: 1.887 ± 0.463
1.887GlnVal: 1.887 ± 0.767
0.0GlnTrp: 0.0 ± 0.0
0.809GlnTyr: 0.809 ± 0.405
0.0GlnXaa: 0.0 ± 0.0
Arg
3.504ArgAla: 3.504 ± 0.639
1.348ArgCys: 1.348 ± 0.335
2.426ArgAsp: 2.426 ± 0.408
2.695ArgGlu: 2.695 ± 0.896
2.426ArgPhe: 2.426 ± 0.783
4.313ArgGly: 4.313 ± 0.823
1.617ArgHis: 1.617 ± 0.416
5.391ArgIle: 5.391 ± 1.214
4.852ArgLys: 4.852 ± 1.801
5.121ArgLeu: 5.121 ± 1.019
2.426ArgMet: 2.426 ± 1.188
0.809ArgAsn: 0.809 ± 0.208
2.426ArgPro: 2.426 ± 1.156
1.887ArgGln: 1.887 ± 0.523
4.582ArgArg: 4.582 ± 1.272
5.93ArgSer: 5.93 ± 0.844
3.774ArgThr: 3.774 ± 0.599
3.774ArgVal: 3.774 ± 1.047
1.348ArgTrp: 1.348 ± 0.67
0.539ArgTyr: 0.539 ± 0.169
0.0ArgXaa: 0.0 ± 0.0
Ser
4.852SerAla: 4.852 ± 1.632
3.504SerCys: 3.504 ± 0.541
5.391SerAsp: 5.391 ± 1.721
3.504SerGlu: 3.504 ± 0.877
2.695SerPhe: 2.695 ± 1.417
8.086SerGly: 8.086 ± 1.023
2.426SerHis: 2.426 ± 0.667
5.66SerIle: 5.66 ± 0.701
4.313SerLys: 4.313 ± 1.151
9.704SerLeu: 9.704 ± 0.666
1.078SerMet: 1.078 ± 0.337
3.235SerAsn: 3.235 ± 0.574
2.695SerPro: 2.695 ± 0.341
3.774SerGln: 3.774 ± 0.708
6.739SerArg: 6.739 ± 0.878
6.199SerSer: 6.199 ± 1.176
4.313SerThr: 4.313 ± 1.766
4.582SerVal: 4.582 ± 0.578
1.348SerTrp: 1.348 ± 0.896
1.348SerTyr: 1.348 ± 1.065
0.0SerXaa: 0.0 ± 0.0
Thr
2.695ThrAla: 2.695 ± 0.752
1.887ThrCys: 1.887 ± 1.366
2.426ThrAsp: 2.426 ± 0.465
4.852ThrGlu: 4.852 ± 1.418
2.695ThrPhe: 2.695 ± 0.845
2.426ThrGly: 2.426 ± 0.437
1.078ThrHis: 1.078 ± 0.368
2.426ThrIle: 2.426 ± 0.298
2.695ThrLys: 2.695 ± 0.843
5.121ThrLeu: 5.121 ± 1.65
1.348ThrMet: 1.348 ± 0.602
2.426ThrAsn: 2.426 ± 0.667
2.695ThrPro: 2.695 ± 1.762
1.887ThrGln: 1.887 ± 0.702
4.043ThrArg: 4.043 ± 1.052
6.199ThrSer: 6.199 ± 1.385
2.965ThrThr: 2.965 ± 0.526
2.695ThrVal: 2.695 ± 0.907
0.539ThrTrp: 0.539 ± 0.435
0.809ThrTyr: 0.809 ± 0.208
0.0ThrXaa: 0.0 ± 0.0
Val
2.426ValAla: 2.426 ± 1.384
1.887ValCys: 1.887 ± 0.504
3.235ValAsp: 3.235 ± 1.28
2.965ValGlu: 2.965 ± 0.75
3.504ValPhe: 3.504 ± 0.721
5.391ValGly: 5.391 ± 1.198
1.078ValHis: 1.078 ± 0.339
2.695ValIle: 2.695 ± 0.561
4.582ValLys: 4.582 ± 0.28
8.086ValLeu: 8.086 ± 1.563
1.078ValMet: 1.078 ± 0.337
1.617ValAsn: 1.617 ± 0.289
2.426ValPro: 2.426 ± 0.755
1.348ValGln: 1.348 ± 1.017
3.774ValArg: 3.774 ± 1.344
5.391ValSer: 5.391 ± 1.153
3.235ValThr: 3.235 ± 0.574
4.043ValVal: 4.043 ± 0.7
1.078ValTrp: 1.078 ± 0.324
1.887ValTyr: 1.887 ± 0.269
0.0ValXaa: 0.0 ± 0.0
Trp
1.078TrpAla: 1.078 ± 0.324
0.27TrpCys: 0.27 ± 0.153
0.27TrpAsp: 0.27 ± 0.246
0.809TrpGlu: 0.809 ± 0.44
1.348TrpPhe: 1.348 ± 0.376
0.539TrpGly: 0.539 ± 0.306
0.27TrpHis: 0.27 ± 0.153
1.348TrpIle: 1.348 ± 0.335
1.078TrpLys: 1.078 ± 0.666
1.348TrpLeu: 1.348 ± 0.552
0.0TrpMet: 0.0 ± 0.0
0.27TrpAsn: 0.27 ± 0.153
0.539TrpPro: 0.539 ± 0.989
0.809TrpGln: 0.809 ± 0.431
1.617TrpArg: 1.617 ± 0.289
0.809TrpSer: 0.809 ± 0.393
0.539TrpThr: 0.539 ± 0.435
0.809TrpVal: 0.809 ± 0.459
0.0TrpTrp: 0.0 ± 0.0
0.27TrpTyr: 0.27 ± 0.153
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.078TyrAla: 1.078 ± 0.324
0.27TyrCys: 0.27 ± 0.246
0.809TyrAsp: 0.809 ± 0.63
0.809TyrGlu: 0.809 ± 0.208
1.887TyrPhe: 1.887 ± 0.988
0.809TyrGly: 0.809 ± 0.63
1.078TyrHis: 1.078 ± 0.612
1.617TyrIle: 1.617 ± 0.396
1.348TyrLys: 1.348 ± 0.765
2.695TyrLeu: 2.695 ± 1.084
0.539TyrMet: 0.539 ± 0.169
0.27TyrAsn: 0.27 ± 0.153
1.617TyrPro: 1.617 ± 1.104
0.539TyrGln: 0.539 ± 0.435
1.887TyrArg: 1.887 ± 0.342
1.887TyrSer: 1.887 ± 0.838
1.078TyrThr: 1.078 ± 0.478
1.078TyrVal: 1.078 ± 0.337
0.27TyrTrp: 0.27 ± 0.494
0.27TyrTyr: 0.27 ± 0.153
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski