Amino acid dipepetide frequency for Beihai picorna-like virus 44

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.717AlaAla: 2.717 ± 1.82
1.553AlaCys: 1.553 ± 0.201
2.717AlaAsp: 2.717 ± 1.152
2.329AlaGlu: 2.329 ± 0.635
3.106AlaPhe: 3.106 ± 1.07
3.106AlaGly: 3.106 ± 0.267
1.165AlaHis: 1.165 ± 0.652
2.329AlaIle: 2.329 ± 0.033
3.106AlaLys: 3.106 ± 2.271
2.329AlaLeu: 2.329 ± 1.369
1.165AlaMet: 1.165 ± 0.652
2.717AlaAsn: 2.717 ± 0.484
3.494AlaPro: 3.494 ± 0.049
1.553AlaGln: 1.553 ± 0.467
1.165AlaArg: 1.165 ± 1.353
6.599AlaSer: 6.599 ± 3.657
2.717AlaThr: 2.717 ± 1.82
3.882AlaVal: 3.882 ± 1.836
0.388AlaTrp: 0.388 ± 0.451
2.717AlaTyr: 2.717 ± 0.184
0.0AlaXaa: 0.0 ± 0.0
Cys
1.165CysAla: 1.165 ± 0.652
0.0CysCys: 0.0 ± 0.0
0.388CysAsp: 0.388 ± 0.217
1.553CysGlu: 1.553 ± 0.869
1.941CysPhe: 1.941 ± 0.918
1.553CysGly: 1.553 ± 0.869
0.388CysHis: 0.388 ± 0.451
2.717CysIle: 2.717 ± 0.184
0.776CysLys: 0.776 ± 0.434
1.165CysLeu: 1.165 ± 0.016
0.0CysMet: 0.0 ± 0.0
0.776CysAsn: 0.776 ± 0.234
1.553CysPro: 1.553 ± 0.869
0.0CysGln: 0.0 ± 0.0
0.388CysArg: 0.388 ± 0.217
1.553CysSer: 1.553 ± 0.869
0.776CysThr: 0.776 ± 0.434
1.941CysVal: 1.941 ± 0.25
0.0CysTrp: 0.0 ± 0.0
1.553CysTyr: 1.553 ± 0.467
0.0CysXaa: 0.0 ± 0.0
Asp
1.941AspAla: 1.941 ± 0.418
0.388AspCys: 0.388 ± 0.217
1.941AspAsp: 1.941 ± 1.086
5.823AspGlu: 5.823 ± 0.082
3.882AspPhe: 3.882 ± 0.5
3.106AspGly: 3.106 ± 0.935
0.776AspHis: 0.776 ± 0.434
6.599AspIle: 6.599 ± 0.352
3.882AspLys: 3.882 ± 1.504
3.882AspLeu: 3.882 ± 0.836
1.165AspMet: 1.165 ± 0.016
2.329AspAsn: 2.329 ± 1.369
2.329AspPro: 2.329 ± 0.701
1.165AspGln: 1.165 ± 0.016
1.941AspArg: 1.941 ± 1.086
2.329AspSer: 2.329 ± 0.701
2.329AspThr: 2.329 ± 0.033
3.494AspVal: 3.494 ± 0.718
1.165AspTrp: 1.165 ± 0.652
1.941AspTyr: 1.941 ± 0.418
0.0AspXaa: 0.0 ± 0.0
Glu
1.553GluAla: 1.553 ± 0.201
1.165GluCys: 1.165 ± 0.652
3.494GluAsp: 3.494 ± 1.287
5.435GluGlu: 5.435 ± 1.705
5.047GluPhe: 5.047 ± 0.819
1.941GluGly: 1.941 ± 0.918
0.776GluHis: 0.776 ± 0.434
4.658GluIle: 4.658 ± 0.602
4.658GluLys: 4.658 ± 1.938
5.823GluLeu: 5.823 ± 0.586
2.717GluMet: 2.717 ± 0.484
2.717GluAsn: 2.717 ± 0.484
1.941GluPro: 1.941 ± 1.086
3.494GluGln: 3.494 ± 1.955
3.882GluArg: 3.882 ± 0.836
3.882GluSer: 3.882 ± 0.168
4.27GluThr: 4.27 ± 1.619
3.882GluVal: 3.882 ± 1.168
0.776GluTrp: 0.776 ± 0.234
4.27GluTyr: 4.27 ± 0.385
0.0GluXaa: 0.0 ± 0.0
Phe
3.494PheAla: 3.494 ± 2.054
1.553PheCys: 1.553 ± 0.201
3.494PheAsp: 3.494 ± 1.287
1.941PheGlu: 1.941 ± 1.086
1.941PhePhe: 1.941 ± 0.918
3.494PheGly: 3.494 ± 2.722
1.553PheHis: 1.553 ± 0.467
3.882PheIle: 3.882 ± 2.172
3.494PheLys: 3.494 ± 0.619
6.211PheLeu: 6.211 ± 0.135
1.165PheMet: 1.165 ± 0.652
4.658PheAsn: 4.658 ± 1.402
1.165PhePro: 1.165 ± 0.016
3.106PheGln: 3.106 ± 1.07
2.329PheArg: 2.329 ± 0.033
3.882PheSer: 3.882 ± 0.836
2.329PheThr: 2.329 ± 0.033
1.941PheVal: 1.941 ± 0.418
0.388PheTrp: 0.388 ± 0.217
3.494PheTyr: 3.494 ± 1.287
0.0PheXaa: 0.0 ± 0.0
Gly
4.27GlyAla: 4.27 ± 1.619
0.0GlyCys: 0.0 ± 0.0
4.27GlyAsp: 4.27 ± 0.385
4.27GlyGlu: 4.27 ± 1.619
0.776GlyPhe: 0.776 ± 0.234
2.329GlyGly: 2.329 ± 1.369
1.165GlyHis: 1.165 ± 0.652
4.27GlyIle: 4.27 ± 0.283
4.27GlyLys: 4.27 ± 0.385
3.494GlyLeu: 3.494 ± 0.718
1.553GlyMet: 1.553 ± 0.467
2.717GlyAsn: 2.717 ± 0.852
2.717GlyPro: 2.717 ± 0.484
0.388GlyGln: 0.388 ± 0.217
0.0GlyArg: 0.0 ± 0.0
4.658GlySer: 4.658 ± 2.738
3.106GlyThr: 3.106 ± 2.271
2.717GlyVal: 2.717 ± 0.484
0.776GlyTrp: 0.776 ± 0.234
1.165GlyTyr: 1.165 ± 0.685
0.0GlyXaa: 0.0 ± 0.0
His
1.165HisAla: 1.165 ± 0.652
0.388HisCys: 0.388 ± 0.217
1.553HisAsp: 1.553 ± 0.869
1.165HisGlu: 1.165 ± 0.016
0.0HisPhe: 0.0 ± 0.0
0.388HisGly: 0.388 ± 0.451
0.776HisHis: 0.776 ± 0.434
1.165HisIle: 1.165 ± 0.652
2.329HisLys: 2.329 ± 0.635
1.553HisLeu: 1.553 ± 0.201
0.388HisMet: 0.388 ± 0.217
0.388HisAsn: 0.388 ± 0.217
0.776HisPro: 0.776 ± 0.234
0.388HisGln: 0.388 ± 0.217
0.388HisArg: 0.388 ± 0.217
2.329HisSer: 2.329 ± 1.303
1.165HisThr: 1.165 ± 0.016
0.776HisVal: 0.776 ± 0.234
0.0HisTrp: 0.0 ± 0.0
0.776HisTyr: 0.776 ± 0.234
0.0HisXaa: 0.0 ± 0.0
Ile
2.329IleAla: 2.329 ± 0.033
2.717IleCys: 2.717 ± 0.852
3.494IleAsp: 3.494 ± 1.386
4.658IleGlu: 4.658 ± 0.066
3.882IlePhe: 3.882 ± 0.836
1.553IleGly: 1.553 ± 0.467
1.941IleHis: 1.941 ± 1.086
5.435IleIle: 5.435 ± 1.705
6.211IleLys: 6.211 ± 2.807
6.988IleLeu: 6.988 ± 3.91
2.717IleMet: 2.717 ± 0.852
4.27IleAsn: 4.27 ± 0.283
3.106IlePro: 3.106 ± 1.07
0.776IleGln: 0.776 ± 0.434
5.047IleArg: 5.047 ± 1.185
8.152IleSer: 8.152 ± 0.553
5.823IleThr: 5.823 ± 1.419
3.106IleVal: 3.106 ± 1.07
0.0IleTrp: 0.0 ± 0.0
1.553IleTyr: 1.553 ± 0.201
0.0IleXaa: 0.0 ± 0.0
Lys
4.27LysAla: 4.27 ± 0.283
1.553LysCys: 1.553 ± 0.869
3.106LysAsp: 3.106 ± 0.267
5.435LysGlu: 5.435 ± 3.041
2.717LysPhe: 2.717 ± 0.852
2.329LysGly: 2.329 ± 0.033
1.165LysHis: 1.165 ± 0.652
2.717LysIle: 2.717 ± 0.852
4.27LysLys: 4.27 ± 0.283
5.823LysLeu: 5.823 ± 1.254
2.717LysMet: 2.717 ± 1.52
2.329LysAsn: 2.329 ± 2.037
3.494LysPro: 3.494 ± 0.718
2.329LysGln: 2.329 ± 0.033
5.047LysArg: 5.047 ± 2.824
4.27LysSer: 4.27 ± 1.721
3.494LysThr: 3.494 ± 1.287
1.553LysVal: 1.553 ± 0.201
0.388LysTrp: 0.388 ± 0.217
2.717LysTyr: 2.717 ± 1.52
0.0LysXaa: 0.0 ± 0.0
Leu
3.106LeuAla: 3.106 ± 2.271
1.553LeuCys: 1.553 ± 0.869
3.882LeuAsp: 3.882 ± 1.168
6.599LeuGlu: 6.599 ± 1.688
2.717LeuPhe: 2.717 ± 0.484
3.494LeuGly: 3.494 ± 0.049
1.553LeuHis: 1.553 ± 0.869
8.54LeuIle: 8.54 ± 2.774
4.27LeuLys: 4.27 ± 0.385
3.106LeuLeu: 3.106 ± 0.401
3.106LeuMet: 3.106 ± 1.07
4.658LeuAsn: 4.658 ± 0.734
3.494LeuPro: 3.494 ± 0.718
3.882LeuGln: 3.882 ± 1.168
3.106LeuArg: 3.106 ± 1.738
5.823LeuSer: 5.823 ± 1.922
4.27LeuThr: 4.27 ± 0.385
5.047LeuVal: 5.047 ± 0.151
1.165LeuTrp: 1.165 ± 0.685
4.27LeuTyr: 4.27 ± 1.053
0.0LeuXaa: 0.0 ± 0.0
Met
1.165MetAla: 1.165 ± 0.016
0.388MetCys: 0.388 ± 0.217
1.553MetAsp: 1.553 ± 0.201
1.553MetGlu: 1.553 ± 0.869
2.329MetPhe: 2.329 ± 0.635
1.165MetGly: 1.165 ± 0.652
0.388MetHis: 0.388 ± 0.451
0.388MetIle: 0.388 ± 0.451
1.941MetLys: 1.941 ± 0.418
3.494MetLeu: 3.494 ± 1.287
1.553MetMet: 1.553 ± 0.201
1.553MetAsn: 1.553 ± 0.201
0.776MetPro: 0.776 ± 0.434
1.941MetGln: 1.941 ± 1.086
1.165MetArg: 1.165 ± 0.652
2.329MetSer: 2.329 ± 0.033
2.329MetThr: 2.329 ± 0.033
1.165MetVal: 1.165 ± 0.685
0.0MetTrp: 0.0 ± 0.0
0.388MetTyr: 0.388 ± 0.217
0.0MetXaa: 0.0 ± 0.0
Asn
3.106AsnAla: 3.106 ± 0.267
0.776AsnCys: 0.776 ± 0.234
1.941AsnAsp: 1.941 ± 1.086
1.165AsnGlu: 1.165 ± 0.685
2.717AsnPhe: 2.717 ± 0.184
1.941AsnGly: 1.941 ± 0.25
1.165AsnHis: 1.165 ± 0.016
5.047AsnIle: 5.047 ± 0.517
3.106AsnLys: 3.106 ± 1.07
2.717AsnLeu: 2.717 ± 0.852
1.165AsnMet: 1.165 ± 0.771
1.941AsnAsn: 1.941 ± 0.25
3.882AsnPro: 3.882 ± 1.836
0.776AsnGln: 0.776 ± 0.434
3.494AsnArg: 3.494 ± 0.718
2.717AsnSer: 2.717 ± 0.484
6.988AsnThr: 6.988 ± 6.112
3.882AsnVal: 3.882 ± 1.168
1.553AsnTrp: 1.553 ± 1.135
3.494AsnTyr: 3.494 ± 0.718
0.0AsnXaa: 0.0 ± 0.0
Pro
1.553ProAla: 1.553 ± 1.804
0.0ProCys: 0.0 ± 0.0
2.717ProAsp: 2.717 ± 0.184
1.553ProGlu: 1.553 ± 0.467
4.658ProPhe: 4.658 ± 1.402
2.329ProGly: 2.329 ± 0.033
0.776ProHis: 0.776 ± 0.234
2.329ProIle: 2.329 ± 0.701
1.553ProLys: 1.553 ± 0.869
5.047ProLeu: 5.047 ± 0.517
0.776ProMet: 0.776 ± 0.234
1.941ProAsn: 1.941 ± 0.25
1.165ProPro: 1.165 ± 0.685
1.165ProGln: 1.165 ± 0.016
0.776ProArg: 0.776 ± 0.234
2.717ProSer: 2.717 ± 0.852
3.106ProThr: 3.106 ± 0.935
3.494ProVal: 3.494 ± 0.718
1.941ProTrp: 1.941 ± 0.418
2.329ProTyr: 2.329 ± 0.701
0.0ProXaa: 0.0 ± 0.0
Gln
0.776GlnAla: 0.776 ± 0.434
0.388GlnCys: 0.388 ± 0.451
1.941GlnAsp: 1.941 ± 0.418
1.941GlnGlu: 1.941 ± 0.418
1.553GlnPhe: 1.553 ± 0.869
1.941GlnGly: 1.941 ± 1.086
1.165GlnHis: 1.165 ± 0.016
2.329GlnIle: 2.329 ± 1.303
1.165GlnLys: 1.165 ± 0.652
2.329GlnLeu: 2.329 ± 0.635
0.388GlnMet: 0.388 ± 0.217
1.941GlnAsn: 1.941 ± 1.586
1.941GlnPro: 1.941 ± 0.918
2.717GlnGln: 2.717 ± 0.852
3.106GlnArg: 3.106 ± 0.267
3.882GlnSer: 3.882 ± 0.5
1.165GlnThr: 1.165 ± 0.652
1.941GlnVal: 1.941 ± 1.086
0.388GlnTrp: 0.388 ± 0.217
1.553GlnTyr: 1.553 ± 1.135
0.0GlnXaa: 0.0 ± 0.0
Arg
1.941ArgAla: 1.941 ± 0.418
1.165ArgCys: 1.165 ± 0.652
2.717ArgAsp: 2.717 ± 0.484
2.329ArgGlu: 2.329 ± 0.635
3.106ArgPhe: 3.106 ± 0.935
3.494ArgGly: 3.494 ± 0.049
0.0ArgHis: 0.0 ± 0.0
1.553ArgIle: 1.553 ± 0.869
4.27ArgLys: 4.27 ± 1.721
3.106ArgLeu: 3.106 ± 0.267
0.776ArgMet: 0.776 ± 0.234
3.494ArgAsn: 3.494 ± 0.049
1.553ArgPro: 1.553 ± 0.467
1.553ArgGln: 1.553 ± 0.869
2.717ArgArg: 2.717 ± 0.484
2.717ArgSer: 2.717 ± 0.852
1.941ArgThr: 1.941 ± 0.418
5.047ArgVal: 5.047 ± 0.517
0.388ArgTrp: 0.388 ± 0.217
2.717ArgTyr: 2.717 ± 0.184
0.0ArgXaa: 0.0 ± 0.0
Ser
4.658SerAla: 4.658 ± 0.066
2.717SerCys: 2.717 ± 0.484
4.27SerAsp: 4.27 ± 0.385
8.152SerGlu: 8.152 ± 0.553
5.047SerPhe: 5.047 ± 0.819
4.27SerGly: 4.27 ± 2.287
0.388SerHis: 0.388 ± 0.217
7.764SerIle: 7.764 ± 1.004
4.27SerLys: 4.27 ± 0.385
7.376SerLeu: 7.376 ± 2.791
0.776SerMet: 0.776 ± 0.234
5.047SerAsn: 5.047 ± 0.151
2.329SerPro: 2.329 ± 0.033
2.329SerGln: 2.329 ± 1.369
3.494SerArg: 3.494 ± 0.718
6.988SerSer: 6.988 ± 1.435
5.047SerThr: 5.047 ± 1.853
6.211SerVal: 6.211 ± 0.803
0.776SerTrp: 0.776 ± 0.234
1.941SerTyr: 1.941 ± 0.918
0.0SerXaa: 0.0 ± 0.0
Thr
4.658ThrAla: 4.658 ± 3.406
0.0ThrCys: 0.0 ± 0.0
2.717ThrAsp: 2.717 ± 1.82
3.882ThrGlu: 3.882 ± 1.168
3.882ThrPhe: 3.882 ± 0.836
3.882ThrGly: 3.882 ± 2.505
1.553ThrHis: 1.553 ± 0.201
5.047ThrIle: 5.047 ± 1.185
1.941ThrLys: 1.941 ± 0.418
5.047ThrLeu: 5.047 ± 2.521
1.553ThrMet: 1.553 ± 0.447
3.106ThrAsn: 3.106 ± 0.935
1.941ThrPro: 1.941 ± 0.918
1.941ThrGln: 1.941 ± 0.418
4.27ThrArg: 4.27 ± 0.385
6.988ThrSer: 6.988 ± 2.103
5.823ThrThr: 5.823 ± 2.087
3.494ThrVal: 3.494 ± 0.718
1.165ThrTrp: 1.165 ± 0.685
3.106ThrTyr: 3.106 ± 1.07
0.0ThrXaa: 0.0 ± 0.0
Val
3.882ValAla: 3.882 ± 1.168
2.717ValCys: 2.717 ± 1.152
2.717ValAsp: 2.717 ± 0.852
5.435ValGlu: 5.435 ± 0.369
2.717ValPhe: 2.717 ± 0.184
2.717ValGly: 2.717 ± 1.152
0.0ValHis: 0.0 ± 0.0
3.106ValIle: 3.106 ± 0.267
2.717ValLys: 2.717 ± 0.184
3.494ValLeu: 3.494 ± 0.049
2.329ValMet: 2.329 ± 1.303
5.047ValAsn: 5.047 ± 0.517
3.106ValPro: 3.106 ± 1.603
2.717ValGln: 2.717 ± 0.484
2.717ValArg: 2.717 ± 0.184
3.882ValSer: 3.882 ± 0.5
4.658ValThr: 4.658 ± 2.07
2.717ValVal: 2.717 ± 1.152
1.553ValTrp: 1.553 ± 0.869
1.553ValTyr: 1.553 ± 0.869
0.0ValXaa: 0.0 ± 0.0
Trp
0.388TrpAla: 0.388 ± 0.451
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.776TrpPhe: 0.776 ± 0.434
0.0TrpGly: 0.0 ± 0.0
0.388TrpHis: 0.388 ± 0.217
0.388TrpIle: 0.388 ± 0.217
0.776TrpLys: 0.776 ± 0.434
1.165TrpLeu: 1.165 ± 0.685
0.776TrpMet: 0.776 ± 0.902
0.776TrpAsn: 0.776 ± 0.234
0.0TrpPro: 0.0 ± 0.0
0.776TrpGln: 0.776 ± 0.234
1.553TrpArg: 1.553 ± 0.201
1.553TrpSer: 1.553 ± 0.201
1.941TrpThr: 1.941 ± 0.25
1.165TrpVal: 1.165 ± 0.016
0.0TrpTrp: 0.0 ± 0.0
1.941TrpTyr: 1.941 ± 0.418
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.717TyrAla: 2.717 ± 1.152
1.165TyrCys: 1.165 ± 0.652
3.494TyrAsp: 3.494 ± 0.049
1.165TyrGlu: 1.165 ± 0.016
2.717TyrPhe: 2.717 ± 0.184
3.882TyrGly: 3.882 ± 0.168
0.776TyrHis: 0.776 ± 0.434
3.494TyrIle: 3.494 ± 1.287
2.717TyrLys: 2.717 ± 0.852
3.494TyrLeu: 3.494 ± 0.718
0.388TyrMet: 0.388 ± 0.217
1.553TyrAsn: 1.553 ± 0.467
1.165TyrPro: 1.165 ± 0.685
1.553TyrGln: 1.553 ± 0.201
0.0TyrArg: 0.0 ± 0.0
6.599TyrSer: 6.599 ± 0.352
2.717TyrThr: 2.717 ± 0.852
2.329TyrVal: 2.329 ± 0.635
1.553TyrTrp: 1.553 ± 0.201
3.106TyrTyr: 3.106 ± 0.401
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2577 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski