Aichi virus (strain Human/A846/88/1989) (AiV) (Aichi virus (strain A846/88))

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Kobuvirus; Aichivirus A; Aichi virus 1

Average proteome isoelectric point is 5.73

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|O91464|POLG_AIVA8 Genome polyprotein OS=Aichi virus (strain Human/A846/88/1989) OX=650132 PE=1 SV=2
MM1 pKa = 7.49AATRR5 pKa = 11.84VSRR8 pKa = 11.84SVLAAVAHH16 pKa = 5.86SAAHH20 pKa = 5.27RR21 pKa = 11.84TYY23 pKa = 9.92HH24 pKa = 5.8TVLDD28 pKa = 4.61CYY30 pKa = 11.33DD31 pKa = 3.61RR32 pKa = 11.84LYY34 pKa = 11.47LNTNPHH40 pKa = 6.71LSYY43 pKa = 10.51PLPKK47 pKa = 10.1NSSFPCPFCQYY58 pKa = 11.15DD59 pKa = 3.6EE60 pKa = 4.36QNEE63 pKa = 4.3VLSPEE68 pKa = 4.18SLRR71 pKa = 11.84GEE73 pKa = 4.21GAEE76 pKa = 4.21PCWKK80 pKa = 10.27CSQDD84 pKa = 3.27KK85 pKa = 10.16PRR87 pKa = 11.84RR88 pKa = 11.84KK89 pKa = 10.45YY90 pKa = 9.52NTTPPEE96 pKa = 3.8DD97 pKa = 3.28WLYY100 pKa = 11.54DD101 pKa = 3.44SDD103 pKa = 4.25VQSWFYY109 pKa = 10.98PEE111 pKa = 4.55TYY113 pKa = 10.67YY114 pKa = 11.43SDD116 pKa = 3.86LQQKK120 pKa = 9.28FFDD123 pKa = 4.09KK124 pKa = 10.85LALLSLPGAYY134 pKa = 8.7QAKK137 pKa = 8.34TPEE140 pKa = 3.78EE141 pKa = 3.9RR142 pKa = 11.84ALAGALTQLLNFPSTPPLTLPTTNLQRR169 pKa = 11.84QGNSVTNIYY178 pKa = 11.18GNGNNVTTDD187 pKa = 2.86VGANGWAPTVSTGLGDD203 pKa = 4.13GPVSASADD211 pKa = 3.73SLPGRR216 pKa = 11.84SGGASSEE223 pKa = 4.14KK224 pKa = 8.64THH226 pKa = 5.75TVSGSSNKK234 pKa = 9.82VGSRR238 pKa = 11.84FSKK241 pKa = 8.47WWEE244 pKa = 3.47PAAARR249 pKa = 11.84ASEE252 pKa = 4.25SATDD256 pKa = 3.74SAIEE260 pKa = 4.83GIDD263 pKa = 3.53AAGKK267 pKa = 9.59AASKK271 pKa = 10.78AITRR275 pKa = 11.84KK276 pKa = 9.58LDD278 pKa = 3.3RR279 pKa = 11.84PAAPSSTANPQPSLIALNPSATQSGNASILTGSTAPSLLAYY320 pKa = 7.12PTATPVPLPNPDD332 pKa = 3.91EE333 pKa = 4.51PSQPGPSGDD342 pKa = 3.85RR343 pKa = 11.84TWLLDD348 pKa = 3.47TVTWSQEE355 pKa = 3.64FTRR358 pKa = 11.84GWNIAGSNGMQWTGLEE374 pKa = 4.08SLIFPVSTDD383 pKa = 3.71TNWTSTSSPTAYY395 pKa = 9.32PLPFSFVRR403 pKa = 11.84AYY405 pKa = 9.89PDD407 pKa = 3.47SSWAAMYY414 pKa = 7.65NTHH417 pKa = 6.6SMWNCGWRR425 pKa = 11.84VQVTVNGSQFHH436 pKa = 6.62AGALILYY443 pKa = 7.16MVPEE447 pKa = 4.54ATTHH451 pKa = 7.15AIQTARR457 pKa = 11.84DD458 pKa = 3.27NAGFVFPYY466 pKa = 10.55VILNLYY472 pKa = 9.03EE473 pKa = 4.96SNTATIEE480 pKa = 4.01VPYY483 pKa = 10.4ISPTPNTSSGLHH495 pKa = 6.1APWTFYY501 pKa = 11.22LQVLSPLNPPPSLPTSLSCSIYY523 pKa = 8.69VTPVDD528 pKa = 3.99SSFHH532 pKa = 5.39GLRR535 pKa = 11.84YY536 pKa = 9.22LAPQHH541 pKa = 5.68WKK543 pKa = 7.9TRR545 pKa = 11.84AVPGAGTFGSAVAGQEE561 pKa = 4.01LPLCGVRR568 pKa = 11.84AYY570 pKa = 10.12YY571 pKa = 9.57PPNAYY576 pKa = 9.38IPAQVRR582 pKa = 11.84DD583 pKa = 3.66WLEE586 pKa = 3.76FAHH589 pKa = 7.09RR590 pKa = 11.84PGLMATVPWTMADD603 pKa = 3.54EE604 pKa = 4.34PAEE607 pKa = 3.95RR608 pKa = 11.84LGIFPVSPSAIAGTGAPISYY628 pKa = 9.97VISLFSQWRR637 pKa = 11.84GEE639 pKa = 4.13LAAHH643 pKa = 7.18LLFTGSAQHH652 pKa = 5.77YY653 pKa = 8.55GRR655 pKa = 11.84LVVCYY660 pKa = 9.12TPAAPQPPSTMQEE673 pKa = 3.98AMRR676 pKa = 11.84GTYY679 pKa = 7.3TVWDD683 pKa = 3.86VNAASTLEE691 pKa = 3.83FTIPFISNSYY701 pKa = 8.55WKK703 pKa = 9.05TVDD706 pKa = 3.39VNNPDD711 pKa = 3.84ALLSTTGYY719 pKa = 10.25VSIWVQNPLVGPHH732 pKa = 6.09TAPASALVQAFISAGEE748 pKa = 4.2SFNVRR753 pKa = 11.84LMQNPALTSQTLTEE767 pKa = 5.28DD768 pKa = 3.43LDD770 pKa = 4.19APQDD774 pKa = 3.4TGNIEE779 pKa = 3.91NGAADD784 pKa = 4.23NSPQPRR790 pKa = 11.84TTFDD794 pKa = 3.29YY795 pKa = 10.45TGNPLPPDD803 pKa = 3.5TKK805 pKa = 11.02LEE807 pKa = 4.18NFFSFYY813 pKa = 10.81RR814 pKa = 11.84LLPMGGSGAPSLSFPADD831 pKa = 3.31EE832 pKa = 4.46GTIIPLNPINWLKK845 pKa = 10.73GADD848 pKa = 3.68VSGIAAMLSCFTYY861 pKa = 10.07IAADD865 pKa = 3.45LRR867 pKa = 11.84ITLRR871 pKa = 11.84FSNPNDD877 pKa = 3.6NPATMLVAFAPPGATIPLKK896 pKa = 9.33PTRR899 pKa = 11.84QMLSNFYY906 pKa = 8.77MAEE909 pKa = 4.17VPVSAATSTMVSFSIPYY926 pKa = 8.49TSPLSAIPTSYY937 pKa = 10.55FGWEE941 pKa = 4.18DD942 pKa = 2.97WSGTNFGQLSSGSWGNLMLIPSLSVDD968 pKa = 3.35SAIPFDD974 pKa = 4.17FQLSCWVAFGNFKK987 pKa = 10.63AWVPRR992 pKa = 11.84PPPPLPPLPTPAANAEE1008 pKa = 4.04RR1009 pKa = 11.84TVAVIKK1015 pKa = 10.67QGAASATPDD1024 pKa = 3.36VDD1026 pKa = 3.58PDD1028 pKa = 3.44DD1029 pKa = 3.42RR1030 pKa = 11.84VYY1032 pKa = 10.49IVRR1035 pKa = 11.84AQRR1038 pKa = 11.84PTYY1041 pKa = 8.2VHH1043 pKa = 5.47WAIRR1047 pKa = 11.84KK1048 pKa = 6.65VAPDD1052 pKa = 4.04GSAKK1056 pKa = 10.27QISLSRR1062 pKa = 11.84SGIQALVALEE1072 pKa = 4.16PPEE1075 pKa = 4.35GEE1077 pKa = 4.41PYY1079 pKa = 10.95LEE1081 pKa = 4.58ILPSHH1086 pKa = 5.86WTLAEE1091 pKa = 3.99LQLGNKK1097 pKa = 8.23WEE1099 pKa = 4.07YY1100 pKa = 11.15SATNNCTHH1108 pKa = 6.7FVSSITGEE1116 pKa = 4.21SLPNTGFSLALGIGALTAIAASAAVAVKK1144 pKa = 9.95ALPGIRR1150 pKa = 11.84RR1151 pKa = 11.84QGLLTLSADD1160 pKa = 3.69TEE1162 pKa = 4.76TNQTLNKK1169 pKa = 8.57ITEE1172 pKa = 4.54SVNQAAQVVSQFDD1185 pKa = 3.55LSGPANSVSLAASDD1199 pKa = 3.59IRR1201 pKa = 11.84EE1202 pKa = 4.25AAHH1205 pKa = 6.9KK1206 pKa = 10.14VASSLNGFTDD1216 pKa = 4.31VIADD1220 pKa = 3.5IKK1222 pKa = 11.18DD1223 pKa = 3.56SLFTRR1228 pKa = 11.84VSDD1231 pKa = 3.66AVEE1234 pKa = 4.2SGVATFLTWLVKK1246 pKa = 10.59LFGYY1250 pKa = 10.61LLVLFGSPTPMSISGLLVIICADD1273 pKa = 4.43LAPHH1277 pKa = 6.14ARR1279 pKa = 11.84EE1280 pKa = 3.93FFTASGNVLSSLYY1293 pKa = 10.46YY1294 pKa = 10.11WIASKK1299 pKa = 10.82LGLSVTPQEE1308 pKa = 4.63CEE1310 pKa = 3.6RR1311 pKa = 11.84ATLEE1315 pKa = 4.06PQGLKK1320 pKa = 10.72DD1321 pKa = 4.21FNDD1324 pKa = 3.92GALAMRR1330 pKa = 11.84NVEE1333 pKa = 4.6WIGEE1337 pKa = 4.45TAWKK1341 pKa = 7.91WAHH1344 pKa = 7.15RR1345 pKa = 11.84LLDD1348 pKa = 4.3WIRR1351 pKa = 11.84GKK1353 pKa = 10.87AKK1355 pKa = 9.8TDD1357 pKa = 3.62PQAKK1361 pKa = 9.71LADD1364 pKa = 3.62VHH1366 pKa = 7.73DD1367 pKa = 5.56EE1368 pKa = 4.15IMLHH1372 pKa = 5.92YY1373 pKa = 10.03SDD1375 pKa = 5.89SILALGSEE1383 pKa = 4.93KK1384 pKa = 10.95LPIDD1388 pKa = 5.2HH1389 pKa = 6.51ITKK1392 pKa = 10.3SISRR1396 pKa = 11.84CRR1398 pKa = 11.84EE1399 pKa = 3.74LVSIAQEE1406 pKa = 4.21AKK1408 pKa = 10.34SGPHH1412 pKa = 6.59SSFLNQAIKK1421 pKa = 10.75NYY1423 pKa = 8.96TLAISQHH1430 pKa = 6.15RR1431 pKa = 11.84KK1432 pKa = 8.4CQTGPRR1438 pKa = 11.84PEE1440 pKa = 4.0PVVVYY1445 pKa = 9.47LYY1447 pKa = 10.62GPPGTGKK1454 pKa = 10.42SLLASLLAQTLSQRR1468 pKa = 11.84LAGTPDD1474 pKa = 3.62DD1475 pKa = 4.4VYY1477 pKa = 11.37SPSSASCEE1485 pKa = 4.06YY1486 pKa = 10.53FDD1488 pKa = 5.81GYY1490 pKa = 9.5TGQTVHH1496 pKa = 7.31FIDD1499 pKa = 6.61DD1500 pKa = 3.65IGQDD1504 pKa = 3.43PEE1506 pKa = 4.1GRR1508 pKa = 11.84DD1509 pKa = 3.06WANFPNLVSSAPFIVPMASLEE1530 pKa = 4.32EE1531 pKa = 4.48KK1532 pKa = 8.81GTHH1535 pKa = 4.73YY1536 pKa = 9.41TSKK1539 pKa = 10.9VIVVTSNFHH1548 pKa = 6.11EE1549 pKa = 4.71PNEE1552 pKa = 4.03RR1553 pKa = 11.84AARR1556 pKa = 11.84SMGALRR1562 pKa = 11.84RR1563 pKa = 11.84RR1564 pKa = 11.84VHH1566 pKa = 6.21LRR1568 pKa = 11.84INVTSNGVPFDD1579 pKa = 3.75PTNALNPIPGTQSKK1593 pKa = 9.91YY1594 pKa = 7.75FTAQTPLTLFQSNTVRR1610 pKa = 11.84LDD1612 pKa = 3.4RR1613 pKa = 11.84DD1614 pKa = 4.42SIWTPTFTNMDD1625 pKa = 4.17EE1626 pKa = 4.19LVDD1629 pKa = 5.07AIVTRR1634 pKa = 11.84LDD1636 pKa = 3.2RR1637 pKa = 11.84STGVSNSLASLIRR1650 pKa = 11.84RR1651 pKa = 11.84QGNRR1655 pKa = 11.84VIDD1658 pKa = 3.81AEE1660 pKa = 4.01PRR1662 pKa = 11.84EE1663 pKa = 4.33IPLEE1667 pKa = 4.1YY1668 pKa = 10.71ADD1670 pKa = 5.61DD1671 pKa = 4.22LLEE1674 pKa = 4.95AMAHH1678 pKa = 5.8HH1679 pKa = 6.69RR1680 pKa = 11.84PVPCSLGLSQAIANNTPIQQISEE1703 pKa = 4.52TFWKK1707 pKa = 9.45YY1708 pKa = 10.3RR1709 pKa = 11.84KK1710 pKa = 9.59PIFTCTTFLAVLGFLCSVIPLARR1733 pKa = 11.84SLWKK1737 pKa = 10.47SKK1739 pKa = 10.59QDD1741 pKa = 3.62TPQEE1745 pKa = 3.87PQAAYY1750 pKa = 10.51SAISHH1755 pKa = 5.83QKK1757 pKa = 9.88PKK1759 pKa = 10.33PKK1761 pKa = 9.87SQKK1764 pKa = 9.43PVPTRR1769 pKa = 11.84HH1770 pKa = 6.0IQRR1773 pKa = 11.84QGISPAVPGISNNVVHH1789 pKa = 6.28VEE1791 pKa = 4.31SGNGLNKK1798 pKa = 10.34NVMSGFYY1805 pKa = 10.0IFSRR1809 pKa = 11.84FLLVPTHH1816 pKa = 6.11LRR1818 pKa = 11.84EE1819 pKa = 4.11PHH1821 pKa = 5.88HH1822 pKa = 6.08TTLTVGADD1830 pKa = 3.32TYY1832 pKa = 11.88DD1833 pKa = 3.2WATLQTQEE1841 pKa = 4.5FGEE1844 pKa = 4.2ITIVHH1849 pKa = 6.56TPTSRR1854 pKa = 11.84QYY1856 pKa = 10.62KK1857 pKa = 9.61DD1858 pKa = 2.91MRR1860 pKa = 11.84RR1861 pKa = 11.84FIGAHH1866 pKa = 4.85PHH1868 pKa = 5.13PTGLLVSQFKK1878 pKa = 10.19AAPLYY1883 pKa = 10.97VRR1885 pKa = 11.84ISDD1888 pKa = 4.43NRR1890 pKa = 11.84ILDD1893 pKa = 3.61LDD1895 pKa = 3.91FPGVVVCKK1903 pKa = 9.91QAYY1906 pKa = 8.79GYY1908 pKa = 10.34RR1909 pKa = 11.84AATFEE1914 pKa = 4.3GLCGSPLVTDD1924 pKa = 4.67DD1925 pKa = 3.78PSGVKK1930 pKa = 9.91ILGLHH1935 pKa = 5.02VAGVAGTSGFSAPIHH1950 pKa = 6.54PILGQITQFATTQQSLIVPTAEE1972 pKa = 3.57VRR1974 pKa = 11.84PGVNVNRR1981 pKa = 11.84MSRR1984 pKa = 11.84LHH1986 pKa = 6.62PSPAYY1991 pKa = 10.2GAFPVKK1997 pKa = 10.19KK1998 pKa = 10.16QPAPLKK2004 pKa = 10.81RR2005 pKa = 11.84NDD2007 pKa = 3.02KK2008 pKa = 10.28RR2009 pKa = 11.84LQEE2012 pKa = 4.46GVDD2015 pKa = 4.09LDD2017 pKa = 3.85TQLFLKK2023 pKa = 10.1HH2024 pKa = 6.02GKK2026 pKa = 10.66GDD2028 pKa = 3.68VTEE2031 pKa = 4.49PWPGLEE2037 pKa = 4.31AAADD2041 pKa = 4.31LYY2043 pKa = 11.28FSTFPTSLPVLTQEE2057 pKa = 4.33QAIHH2061 pKa = 5.83GTPNMEE2067 pKa = 4.3GLDD2070 pKa = 3.62MGQAAGYY2077 pKa = 7.73PWNTLGRR2084 pKa = 11.84SRR2086 pKa = 11.84RR2087 pKa = 11.84SLFDD2091 pKa = 3.25EE2092 pKa = 4.33VEE2094 pKa = 4.19PGVFVPKK2101 pKa = 10.34PEE2103 pKa = 4.0LQAEE2107 pKa = 4.34INQTLEE2113 pKa = 4.28DD2114 pKa = 4.09PDD2116 pKa = 3.98YY2117 pKa = 11.45VYY2119 pKa = 10.45STFLKK2124 pKa = 10.93DD2125 pKa = 3.65EE2126 pKa = 4.49LRR2128 pKa = 11.84PTAKK2132 pKa = 10.19VEE2134 pKa = 3.89QGLTRR2139 pKa = 11.84IVEE2142 pKa = 4.15AAPIHH2147 pKa = 6.33AIVAGRR2153 pKa = 11.84MLLGGLIDD2161 pKa = 3.95YY2162 pKa = 7.52MQGRR2166 pKa = 11.84PGEE2169 pKa = 4.41HH2170 pKa = 6.67GSAVGCNPDD2179 pKa = 3.38VHH2181 pKa = 5.83WTSFFYY2187 pKa = 10.82AFSEE2191 pKa = 4.83FSQVYY2196 pKa = 10.38DD2197 pKa = 4.2LDD2199 pKa = 4.25YY2200 pKa = 11.4KK2201 pKa = 11.28CFDD2204 pKa = 3.42ATLPSAVFTLVADD2217 pKa = 3.68HH2218 pKa = 6.72LTRR2221 pKa = 11.84ITGDD2225 pKa = 3.49PRR2227 pKa = 11.84VGRR2230 pKa = 11.84YY2231 pKa = 6.88IHH2233 pKa = 6.6SIRR2236 pKa = 11.84HH2237 pKa = 4.08SHH2239 pKa = 6.85HH2240 pKa = 6.46IYY2242 pKa = 9.75GNRR2245 pKa = 11.84MYY2247 pKa = 11.55DD2248 pKa = 3.4MIGGNPSGCVATSILNTIINNICVLSALIQHH2279 pKa = 7.17PDD2281 pKa = 3.71FSPSRR2286 pKa = 11.84FHH2288 pKa = 7.64ILAYY2292 pKa = 10.27GDD2294 pKa = 3.62DD2295 pKa = 4.18VIYY2298 pKa = 9.04ATEE2301 pKa = 4.17PPIHH2305 pKa = 6.85PSFLRR2310 pKa = 11.84EE2311 pKa = 4.48FYY2313 pKa = 10.44QKK2315 pKa = 8.87HH2316 pKa = 5.09TPLVVTPANKK2326 pKa = 10.35GQDD2329 pKa = 3.84FPPTSTIYY2337 pKa = 10.61EE2338 pKa = 4.18VTFLKK2343 pKa = 10.39RR2344 pKa = 11.84WFVPDD2349 pKa = 3.95DD2350 pKa = 3.32VRR2352 pKa = 11.84PIYY2355 pKa = 9.79IHH2357 pKa = 6.97PVMDD2361 pKa = 5.46PDD2363 pKa = 3.93TYY2365 pKa = 9.81EE2366 pKa = 4.03QSVMWLRR2373 pKa = 11.84DD2374 pKa = 2.86GDD2376 pKa = 4.0FQDD2379 pKa = 4.37VVTSLCHH2386 pKa = 6.3LAFHH2390 pKa = 7.05SGPKK2394 pKa = 9.32TYY2396 pKa = 10.5AAWCMKK2402 pKa = 9.97VRR2404 pKa = 11.84EE2405 pKa = 4.21QCLKK2409 pKa = 11.0SGFAPNFLPYY2419 pKa = 10.44SYY2421 pKa = 11.16LQLRR2425 pKa = 11.84WLNLLAAA2432 pKa = 5.25

Molecular weight: 265.46 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|O91464|POLG_AIVA8 Genome polyprotein OS=Aichi virus (strain Human/A846/88/1989) OX=650132 PE=1 SV=2
MM1 pKa = 7.49AATRR5 pKa = 11.84VSRR8 pKa = 11.84SVLAAVAHH16 pKa = 5.86SAAHH20 pKa = 5.27RR21 pKa = 11.84TYY23 pKa = 9.92HH24 pKa = 5.8TVLDD28 pKa = 4.61CYY30 pKa = 11.33DD31 pKa = 3.61RR32 pKa = 11.84LYY34 pKa = 11.47LNTNPHH40 pKa = 6.71LSYY43 pKa = 10.51PLPKK47 pKa = 10.1NSSFPCPFCQYY58 pKa = 11.15DD59 pKa = 3.6EE60 pKa = 4.36QNEE63 pKa = 4.3VLSPEE68 pKa = 4.18SLRR71 pKa = 11.84GEE73 pKa = 4.21GAEE76 pKa = 4.21PCWKK80 pKa = 10.27CSQDD84 pKa = 3.27KK85 pKa = 10.16PRR87 pKa = 11.84RR88 pKa = 11.84KK89 pKa = 10.45YY90 pKa = 9.52NTTPPEE96 pKa = 3.8DD97 pKa = 3.28WLYY100 pKa = 11.54DD101 pKa = 3.44SDD103 pKa = 4.25VQSWFYY109 pKa = 10.98PEE111 pKa = 4.55TYY113 pKa = 10.67YY114 pKa = 11.43SDD116 pKa = 3.86LQQKK120 pKa = 9.28FFDD123 pKa = 4.09KK124 pKa = 10.85LALLSLPGAYY134 pKa = 8.7QAKK137 pKa = 8.34TPEE140 pKa = 3.78EE141 pKa = 3.9RR142 pKa = 11.84ALAGALTQLLNFPSTPPLTLPTTNLQRR169 pKa = 11.84QGNSVTNIYY178 pKa = 11.18GNGNNVTTDD187 pKa = 2.86VGANGWAPTVSTGLGDD203 pKa = 4.13GPVSASADD211 pKa = 3.73SLPGRR216 pKa = 11.84SGGASSEE223 pKa = 4.14KK224 pKa = 8.64THH226 pKa = 5.75TVSGSSNKK234 pKa = 9.82VGSRR238 pKa = 11.84FSKK241 pKa = 8.47WWEE244 pKa = 3.47PAAARR249 pKa = 11.84ASEE252 pKa = 4.25SATDD256 pKa = 3.74SAIEE260 pKa = 4.83GIDD263 pKa = 3.53AAGKK267 pKa = 9.59AASKK271 pKa = 10.78AITRR275 pKa = 11.84KK276 pKa = 9.58LDD278 pKa = 3.3RR279 pKa = 11.84PAAPSSTANPQPSLIALNPSATQSGNASILTGSTAPSLLAYY320 pKa = 7.12PTATPVPLPNPDD332 pKa = 3.91EE333 pKa = 4.51PSQPGPSGDD342 pKa = 3.85RR343 pKa = 11.84TWLLDD348 pKa = 3.47TVTWSQEE355 pKa = 3.64FTRR358 pKa = 11.84GWNIAGSNGMQWTGLEE374 pKa = 4.08SLIFPVSTDD383 pKa = 3.71TNWTSTSSPTAYY395 pKa = 9.32PLPFSFVRR403 pKa = 11.84AYY405 pKa = 9.89PDD407 pKa = 3.47SSWAAMYY414 pKa = 7.65NTHH417 pKa = 6.6SMWNCGWRR425 pKa = 11.84VQVTVNGSQFHH436 pKa = 6.62AGALILYY443 pKa = 7.16MVPEE447 pKa = 4.54ATTHH451 pKa = 7.15AIQTARR457 pKa = 11.84DD458 pKa = 3.27NAGFVFPYY466 pKa = 10.55VILNLYY472 pKa = 9.03EE473 pKa = 4.96SNTATIEE480 pKa = 4.01VPYY483 pKa = 10.4ISPTPNTSSGLHH495 pKa = 6.1APWTFYY501 pKa = 11.22LQVLSPLNPPPSLPTSLSCSIYY523 pKa = 8.69VTPVDD528 pKa = 3.99SSFHH532 pKa = 5.39GLRR535 pKa = 11.84YY536 pKa = 9.22LAPQHH541 pKa = 5.68WKK543 pKa = 7.9TRR545 pKa = 11.84AVPGAGTFGSAVAGQEE561 pKa = 4.01LPLCGVRR568 pKa = 11.84AYY570 pKa = 10.12YY571 pKa = 9.57PPNAYY576 pKa = 9.38IPAQVRR582 pKa = 11.84DD583 pKa = 3.66WLEE586 pKa = 3.76FAHH589 pKa = 7.09RR590 pKa = 11.84PGLMATVPWTMADD603 pKa = 3.54EE604 pKa = 4.34PAEE607 pKa = 3.95RR608 pKa = 11.84LGIFPVSPSAIAGTGAPISYY628 pKa = 9.97VISLFSQWRR637 pKa = 11.84GEE639 pKa = 4.13LAAHH643 pKa = 7.18LLFTGSAQHH652 pKa = 5.77YY653 pKa = 8.55GRR655 pKa = 11.84LVVCYY660 pKa = 9.12TPAAPQPPSTMQEE673 pKa = 3.98AMRR676 pKa = 11.84GTYY679 pKa = 7.3TVWDD683 pKa = 3.86VNAASTLEE691 pKa = 3.83FTIPFISNSYY701 pKa = 8.55WKK703 pKa = 9.05TVDD706 pKa = 3.39VNNPDD711 pKa = 3.84ALLSTTGYY719 pKa = 10.25VSIWVQNPLVGPHH732 pKa = 6.09TAPASALVQAFISAGEE748 pKa = 4.2SFNVRR753 pKa = 11.84LMQNPALTSQTLTEE767 pKa = 5.28DD768 pKa = 3.43LDD770 pKa = 4.19APQDD774 pKa = 3.4TGNIEE779 pKa = 3.91NGAADD784 pKa = 4.23NSPQPRR790 pKa = 11.84TTFDD794 pKa = 3.29YY795 pKa = 10.45TGNPLPPDD803 pKa = 3.5TKK805 pKa = 11.02LEE807 pKa = 4.18NFFSFYY813 pKa = 10.81RR814 pKa = 11.84LLPMGGSGAPSLSFPADD831 pKa = 3.31EE832 pKa = 4.46GTIIPLNPINWLKK845 pKa = 10.73GADD848 pKa = 3.68VSGIAAMLSCFTYY861 pKa = 10.07IAADD865 pKa = 3.45LRR867 pKa = 11.84ITLRR871 pKa = 11.84FSNPNDD877 pKa = 3.6NPATMLVAFAPPGATIPLKK896 pKa = 9.33PTRR899 pKa = 11.84QMLSNFYY906 pKa = 8.77MAEE909 pKa = 4.17VPVSAATSTMVSFSIPYY926 pKa = 8.49TSPLSAIPTSYY937 pKa = 10.55FGWEE941 pKa = 4.18DD942 pKa = 2.97WSGTNFGQLSSGSWGNLMLIPSLSVDD968 pKa = 3.35SAIPFDD974 pKa = 4.17FQLSCWVAFGNFKK987 pKa = 10.63AWVPRR992 pKa = 11.84PPPPLPPLPTPAANAEE1008 pKa = 4.04RR1009 pKa = 11.84TVAVIKK1015 pKa = 10.67QGAASATPDD1024 pKa = 3.36VDD1026 pKa = 3.58PDD1028 pKa = 3.44DD1029 pKa = 3.42RR1030 pKa = 11.84VYY1032 pKa = 10.49IVRR1035 pKa = 11.84AQRR1038 pKa = 11.84PTYY1041 pKa = 8.2VHH1043 pKa = 5.47WAIRR1047 pKa = 11.84KK1048 pKa = 6.65VAPDD1052 pKa = 4.04GSAKK1056 pKa = 10.27QISLSRR1062 pKa = 11.84SGIQALVALEE1072 pKa = 4.16PPEE1075 pKa = 4.35GEE1077 pKa = 4.41PYY1079 pKa = 10.95LEE1081 pKa = 4.58ILPSHH1086 pKa = 5.86WTLAEE1091 pKa = 3.99LQLGNKK1097 pKa = 8.23WEE1099 pKa = 4.07YY1100 pKa = 11.15SATNNCTHH1108 pKa = 6.7FVSSITGEE1116 pKa = 4.21SLPNTGFSLALGIGALTAIAASAAVAVKK1144 pKa = 9.95ALPGIRR1150 pKa = 11.84RR1151 pKa = 11.84QGLLTLSADD1160 pKa = 3.69TEE1162 pKa = 4.76TNQTLNKK1169 pKa = 8.57ITEE1172 pKa = 4.54SVNQAAQVVSQFDD1185 pKa = 3.55LSGPANSVSLAASDD1199 pKa = 3.59IRR1201 pKa = 11.84EE1202 pKa = 4.25AAHH1205 pKa = 6.9KK1206 pKa = 10.14VASSLNGFTDD1216 pKa = 4.31VIADD1220 pKa = 3.5IKK1222 pKa = 11.18DD1223 pKa = 3.56SLFTRR1228 pKa = 11.84VSDD1231 pKa = 3.66AVEE1234 pKa = 4.2SGVATFLTWLVKK1246 pKa = 10.59LFGYY1250 pKa = 10.61LLVLFGSPTPMSISGLLVIICADD1273 pKa = 4.43LAPHH1277 pKa = 6.14ARR1279 pKa = 11.84EE1280 pKa = 3.93FFTASGNVLSSLYY1293 pKa = 10.46YY1294 pKa = 10.11WIASKK1299 pKa = 10.82LGLSVTPQEE1308 pKa = 4.63CEE1310 pKa = 3.6RR1311 pKa = 11.84ATLEE1315 pKa = 4.06PQGLKK1320 pKa = 10.72DD1321 pKa = 4.21FNDD1324 pKa = 3.92GALAMRR1330 pKa = 11.84NVEE1333 pKa = 4.6WIGEE1337 pKa = 4.45TAWKK1341 pKa = 7.91WAHH1344 pKa = 7.15RR1345 pKa = 11.84LLDD1348 pKa = 4.3WIRR1351 pKa = 11.84GKK1353 pKa = 10.87AKK1355 pKa = 9.8TDD1357 pKa = 3.62PQAKK1361 pKa = 9.71LADD1364 pKa = 3.62VHH1366 pKa = 7.73DD1367 pKa = 5.56EE1368 pKa = 4.15IMLHH1372 pKa = 5.92YY1373 pKa = 10.03SDD1375 pKa = 5.89SILALGSEE1383 pKa = 4.93KK1384 pKa = 10.95LPIDD1388 pKa = 5.2HH1389 pKa = 6.51ITKK1392 pKa = 10.3SISRR1396 pKa = 11.84CRR1398 pKa = 11.84EE1399 pKa = 3.74LVSIAQEE1406 pKa = 4.21AKK1408 pKa = 10.34SGPHH1412 pKa = 6.59SSFLNQAIKK1421 pKa = 10.75NYY1423 pKa = 8.96TLAISQHH1430 pKa = 6.15RR1431 pKa = 11.84KK1432 pKa = 8.4CQTGPRR1438 pKa = 11.84PEE1440 pKa = 4.0PVVVYY1445 pKa = 9.47LYY1447 pKa = 10.62GPPGTGKK1454 pKa = 10.42SLLASLLAQTLSQRR1468 pKa = 11.84LAGTPDD1474 pKa = 3.62DD1475 pKa = 4.4VYY1477 pKa = 11.37SPSSASCEE1485 pKa = 4.06YY1486 pKa = 10.53FDD1488 pKa = 5.81GYY1490 pKa = 9.5TGQTVHH1496 pKa = 7.31FIDD1499 pKa = 6.61DD1500 pKa = 3.65IGQDD1504 pKa = 3.43PEE1506 pKa = 4.1GRR1508 pKa = 11.84DD1509 pKa = 3.06WANFPNLVSSAPFIVPMASLEE1530 pKa = 4.32EE1531 pKa = 4.48KK1532 pKa = 8.81GTHH1535 pKa = 4.73YY1536 pKa = 9.41TSKK1539 pKa = 10.9VIVVTSNFHH1548 pKa = 6.11EE1549 pKa = 4.71PNEE1552 pKa = 4.03RR1553 pKa = 11.84AARR1556 pKa = 11.84SMGALRR1562 pKa = 11.84RR1563 pKa = 11.84RR1564 pKa = 11.84VHH1566 pKa = 6.21LRR1568 pKa = 11.84INVTSNGVPFDD1579 pKa = 3.75PTNALNPIPGTQSKK1593 pKa = 9.91YY1594 pKa = 7.75FTAQTPLTLFQSNTVRR1610 pKa = 11.84LDD1612 pKa = 3.4RR1613 pKa = 11.84DD1614 pKa = 4.42SIWTPTFTNMDD1625 pKa = 4.17EE1626 pKa = 4.19LVDD1629 pKa = 5.07AIVTRR1634 pKa = 11.84LDD1636 pKa = 3.2RR1637 pKa = 11.84STGVSNSLASLIRR1650 pKa = 11.84RR1651 pKa = 11.84QGNRR1655 pKa = 11.84VIDD1658 pKa = 3.81AEE1660 pKa = 4.01PRR1662 pKa = 11.84EE1663 pKa = 4.33IPLEE1667 pKa = 4.1YY1668 pKa = 10.71ADD1670 pKa = 5.61DD1671 pKa = 4.22LLEE1674 pKa = 4.95AMAHH1678 pKa = 5.8HH1679 pKa = 6.69RR1680 pKa = 11.84PVPCSLGLSQAIANNTPIQQISEE1703 pKa = 4.52TFWKK1707 pKa = 9.45YY1708 pKa = 10.3RR1709 pKa = 11.84KK1710 pKa = 9.59PIFTCTTFLAVLGFLCSVIPLARR1733 pKa = 11.84SLWKK1737 pKa = 10.47SKK1739 pKa = 10.59QDD1741 pKa = 3.62TPQEE1745 pKa = 3.87PQAAYY1750 pKa = 10.51SAISHH1755 pKa = 5.83QKK1757 pKa = 9.88PKK1759 pKa = 10.33PKK1761 pKa = 9.87SQKK1764 pKa = 9.43PVPTRR1769 pKa = 11.84HH1770 pKa = 6.0IQRR1773 pKa = 11.84QGISPAVPGISNNVVHH1789 pKa = 6.28VEE1791 pKa = 4.31SGNGLNKK1798 pKa = 10.34NVMSGFYY1805 pKa = 10.0IFSRR1809 pKa = 11.84FLLVPTHH1816 pKa = 6.11LRR1818 pKa = 11.84EE1819 pKa = 4.11PHH1821 pKa = 5.88HH1822 pKa = 6.08TTLTVGADD1830 pKa = 3.32TYY1832 pKa = 11.88DD1833 pKa = 3.2WATLQTQEE1841 pKa = 4.5FGEE1844 pKa = 4.2ITIVHH1849 pKa = 6.56TPTSRR1854 pKa = 11.84QYY1856 pKa = 10.62KK1857 pKa = 9.61DD1858 pKa = 2.91MRR1860 pKa = 11.84RR1861 pKa = 11.84FIGAHH1866 pKa = 4.85PHH1868 pKa = 5.13PTGLLVSQFKK1878 pKa = 10.19AAPLYY1883 pKa = 10.97VRR1885 pKa = 11.84ISDD1888 pKa = 4.43NRR1890 pKa = 11.84ILDD1893 pKa = 3.61LDD1895 pKa = 3.91FPGVVVCKK1903 pKa = 9.91QAYY1906 pKa = 8.79GYY1908 pKa = 10.34RR1909 pKa = 11.84AATFEE1914 pKa = 4.3GLCGSPLVTDD1924 pKa = 4.67DD1925 pKa = 3.78PSGVKK1930 pKa = 9.91ILGLHH1935 pKa = 5.02VAGVAGTSGFSAPIHH1950 pKa = 6.54PILGQITQFATTQQSLIVPTAEE1972 pKa = 3.57VRR1974 pKa = 11.84PGVNVNRR1981 pKa = 11.84MSRR1984 pKa = 11.84LHH1986 pKa = 6.62PSPAYY1991 pKa = 10.2GAFPVKK1997 pKa = 10.19KK1998 pKa = 10.16QPAPLKK2004 pKa = 10.81RR2005 pKa = 11.84NDD2007 pKa = 3.02KK2008 pKa = 10.28RR2009 pKa = 11.84LQEE2012 pKa = 4.46GVDD2015 pKa = 4.09LDD2017 pKa = 3.85TQLFLKK2023 pKa = 10.1HH2024 pKa = 6.02GKK2026 pKa = 10.66GDD2028 pKa = 3.68VTEE2031 pKa = 4.49PWPGLEE2037 pKa = 4.31AAADD2041 pKa = 4.31LYY2043 pKa = 11.28FSTFPTSLPVLTQEE2057 pKa = 4.33QAIHH2061 pKa = 5.83GTPNMEE2067 pKa = 4.3GLDD2070 pKa = 3.62MGQAAGYY2077 pKa = 7.73PWNTLGRR2084 pKa = 11.84SRR2086 pKa = 11.84RR2087 pKa = 11.84SLFDD2091 pKa = 3.25EE2092 pKa = 4.33VEE2094 pKa = 4.19PGVFVPKK2101 pKa = 10.34PEE2103 pKa = 4.0LQAEE2107 pKa = 4.34INQTLEE2113 pKa = 4.28DD2114 pKa = 4.09PDD2116 pKa = 3.98YY2117 pKa = 11.45VYY2119 pKa = 10.45STFLKK2124 pKa = 10.93DD2125 pKa = 3.65EE2126 pKa = 4.49LRR2128 pKa = 11.84PTAKK2132 pKa = 10.19VEE2134 pKa = 3.89QGLTRR2139 pKa = 11.84IVEE2142 pKa = 4.15AAPIHH2147 pKa = 6.33AIVAGRR2153 pKa = 11.84MLLGGLIDD2161 pKa = 3.95YY2162 pKa = 7.52MQGRR2166 pKa = 11.84PGEE2169 pKa = 4.41HH2170 pKa = 6.67GSAVGCNPDD2179 pKa = 3.38VHH2181 pKa = 5.83WTSFFYY2187 pKa = 10.82AFSEE2191 pKa = 4.83FSQVYY2196 pKa = 10.38DD2197 pKa = 4.2LDD2199 pKa = 4.25YY2200 pKa = 11.4KK2201 pKa = 11.28CFDD2204 pKa = 3.42ATLPSAVFTLVADD2217 pKa = 3.68HH2218 pKa = 6.72LTRR2221 pKa = 11.84ITGDD2225 pKa = 3.49PRR2227 pKa = 11.84VGRR2230 pKa = 11.84YY2231 pKa = 6.88IHH2233 pKa = 6.6SIRR2236 pKa = 11.84HH2237 pKa = 4.08SHH2239 pKa = 6.85HH2240 pKa = 6.46IYY2242 pKa = 9.75GNRR2245 pKa = 11.84MYY2247 pKa = 11.55DD2248 pKa = 3.4MIGGNPSGCVATSILNTIINNICVLSALIQHH2279 pKa = 7.17PDD2281 pKa = 3.71FSPSRR2286 pKa = 11.84FHH2288 pKa = 7.64ILAYY2292 pKa = 10.27GDD2294 pKa = 3.62DD2295 pKa = 4.18VIYY2298 pKa = 9.04ATEE2301 pKa = 4.17PPIHH2305 pKa = 6.85PSFLRR2310 pKa = 11.84EE2311 pKa = 4.48FYY2313 pKa = 10.44QKK2315 pKa = 8.87HH2316 pKa = 5.09TPLVVTPANKK2326 pKa = 10.35GQDD2329 pKa = 3.84FPPTSTIYY2337 pKa = 10.61EE2338 pKa = 4.18VTFLKK2343 pKa = 10.39RR2344 pKa = 11.84WFVPDD2349 pKa = 3.95DD2350 pKa = 3.32VRR2352 pKa = 11.84PIYY2355 pKa = 9.79IHH2357 pKa = 6.97PVMDD2361 pKa = 5.46PDD2363 pKa = 3.93TYY2365 pKa = 9.81EE2366 pKa = 4.03QSVMWLRR2373 pKa = 11.84DD2374 pKa = 2.86GDD2376 pKa = 4.0FQDD2379 pKa = 4.37VVTSLCHH2386 pKa = 6.3LAFHH2390 pKa = 7.05SGPKK2394 pKa = 9.32TYY2396 pKa = 10.5AAWCMKK2402 pKa = 9.97VRR2404 pKa = 11.84EE2405 pKa = 4.21QCLKK2409 pKa = 11.0SGFAPNFLPYY2419 pKa = 10.44SYY2421 pKa = 11.16LQLRR2425 pKa = 11.84WLNLLAAA2432 pKa = 5.25

Molecular weight: 265.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

2432

2432

2432

2432.0

265.46

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.334 ± 0.0

1.192 ± 0.0

4.729 ± 0.0

3.906 ± 0.0

4.112 ± 0.0

6.456 ± 0.0

2.508 ± 0.0

4.77 ± 0.0

2.961 ± 0.0

9.128 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.48 ± 0.0

4.153 ± 0.0

8.594 ± 0.0

3.988 ± 0.0

4.4 ± 0.0

8.882 ± 0.0

7.607 ± 0.0

6.332 ± 0.0

2.015 ± 0.0

3.454 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski