Amino acid dipepetide frequency for Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.398AlaAla: 13.398 ± 0.096	1.099AlaCys: 1.099 ± 0.019	5.505AlaAsp: 5.505 ± 0.048	5.492AlaGlu: 5.492 ± 0.046	3.249AlaPhe: 3.249 ± 0.035	6.579AlaGly: 6.579 ± 0.051	2.437AlaHis: 2.437 ± 0.03	4.194AlaIle: 4.194 ± 0.037	4.788AlaLys: 4.788 ± 0.047	8.755AlaLeu: 8.755 ± 0.06	1.969AlaMet: 1.969 ± 0.022	3.628AlaAsn: 3.628 ± 0.032	5.837AlaPro: 5.837 ± 0.054	4.505AlaGln: 4.505 ± 0.037	6.245AlaArg: 6.245 ± 0.05	12.348AlaSer: 12.348 ± 0.081	6.607AlaThr: 6.607 ± 0.051	5.71AlaVal: 5.71 ± 0.034	1.112AlaTrp: 1.112 ± 0.02	2.131AlaTyr: 2.131 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.959CysAla: 0.959 ± 0.015	0.188CysCys: 0.188 ± 0.008	0.58CysAsp: 0.58 ± 0.013	0.47CysGlu: 0.47 ± 0.012	0.455CysPhe: 0.455 ± 0.01	0.72CysGly: 0.72 ± 0.014	0.277CysHis: 0.277 ± 0.009	0.59CysIle: 0.59 ± 0.013	0.461CysLys: 0.461 ± 0.012	1.056CysLeu: 1.056 ± 0.018	0.214CysMet: 0.214 ± 0.008	0.381CysAsn: 0.381 ± 0.01	0.512CysPro: 0.512 ± 0.013	0.374CysGln: 0.374 ± 0.011	0.637CysArg: 0.637 ± 0.013	1.028CysSer: 1.028 ± 0.021	0.698CysThr: 0.698 ± 0.015	0.654CysVal: 0.654 ± 0.014	0.153CysTrp: 0.153 ± 0.006	0.274CysTyr: 0.274 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.63AspAla: 6.63 ± 0.044	0.497AspCys: 0.497 ± 0.013	5.043AspAsp: 5.043 ± 0.07	4.43AspGlu: 4.43 ± 0.051	1.816AspPhe: 1.816 ± 0.022	3.824AspGly: 3.824 ± 0.034	1.413AspHis: 1.413 ± 0.02	2.134AspIle: 2.134 ± 0.025	2.328AspLys: 2.328 ± 0.031	5.002AspLeu: 5.002 ± 0.039	1.083AspMet: 1.083 ± 0.016	1.635AspAsn: 1.635 ± 0.021	3.214AspPro: 3.214 ± 0.032	2.394AspGln: 2.394 ± 0.029	3.275AspArg: 3.275 ± 0.031	4.597AspSer: 4.597 ± 0.036	2.926AspThr: 2.926 ± 0.027	3.694AspVal: 3.694 ± 0.031	0.767AspTrp: 0.767 ± 0.014	1.259AspTyr: 1.259 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.846GluAla: 5.846 ± 0.051	0.518GluCys: 0.518 ± 0.012	3.332GluAsp: 3.332 ± 0.035	4.006GluGlu: 4.006 ± 0.052	1.493GluPhe: 1.493 ± 0.02	2.703GluGly: 2.703 ± 0.028	1.454GluHis: 1.454 ± 0.019	2.258GluIle: 2.258 ± 0.028	2.682GluLys: 2.682 ± 0.031	5.137GluLeu: 5.137 ± 0.044	1.229GluMet: 1.229 ± 0.019	1.555GluAsn: 1.555 ± 0.02	2.472GluPro: 2.472 ± 0.028	2.893GluGln: 2.893 ± 0.031	3.927GluArg: 3.927 ± 0.039	4.191GluSer: 4.191 ± 0.036	2.96GluThr: 2.96 ± 0.026	2.885GluVal: 2.885 ± 0.029	0.712GluTrp: 0.712 ± 0.014	1.19GluTyr: 1.19 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.2PheAla: 3.2 ± 0.029	0.441PheCys: 0.441 ± 0.011	2.224PheAsp: 2.224 ± 0.028	1.826PheGlu: 1.826 ± 0.021	1.318PhePhe: 1.318 ± 0.022	2.792PheGly: 2.792 ± 0.039	0.788PheHis: 0.788 ± 0.013	1.258PheIle: 1.258 ± 0.021	1.228PheLys: 1.228 ± 0.02	2.831PheLeu: 2.831 ± 0.029	0.601PheMet: 0.601 ± 0.011	1.143PheAsn: 1.143 ± 0.02	1.463PhePro: 1.463 ± 0.021	1.184PheGln: 1.184 ± 0.018	1.768PheArg: 1.768 ± 0.021	2.898PheSer: 2.898 ± 0.027	1.757PheThr: 1.757 ± 0.023	2.262PheVal: 2.262 ± 0.026	0.491PheTrp: 0.491 ± 0.012	0.884PheTyr: 0.884 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	6.504GlyAla: 6.504 ± 0.056	0.692GlyCys: 0.692 ± 0.014	3.18GlyAsp: 3.18 ± 0.039	2.988GlyGlu: 2.988 ± 0.028	2.424GlyPhe: 2.424 ± 0.029	5.706GlyGly: 5.706 ± 0.072	1.558GlyHis: 1.558 ± 0.022	2.89GlyIle: 2.89 ± 0.031	3.13GlyLys: 3.13 ± 0.037	5.678GlyLeu: 5.678 ± 0.036	1.398GlyMet: 1.398 ± 0.021	2.113GlyAsn: 2.113 ± 0.039	2.911GlyPro: 2.911 ± 0.031	2.477GlyGln: 2.477 ± 0.029	3.874GlyArg: 3.874 ± 0.035	6.628GlySer: 6.628 ± 0.056	3.696GlyThr: 3.696 ± 0.032	3.923GlyVal: 3.923 ± 0.038	0.975GlyTrp: 0.975 ± 0.017	1.698GlyTyr: 1.698 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.69HisAla: 2.69 ± 0.029	0.268HisCys: 0.268 ± 0.008	1.523HisAsp: 1.523 ± 0.022	1.253HisGlu: 1.253 ± 0.019	0.874HisPhe: 0.874 ± 0.015	1.641HisGly: 1.641 ± 0.023	1.082HisHis: 1.082 ± 0.025	1.078HisIle: 1.078 ± 0.016	0.939HisLys: 0.939 ± 0.017	2.562HisLeu: 2.562 ± 0.027	0.487HisMet: 0.487 ± 0.011	0.817HisAsn: 0.817 ± 0.016	1.781HisPro: 1.781 ± 0.023	1.231HisGln: 1.231 ± 0.019	1.764HisArg: 1.764 ± 0.022	2.303HisSer: 2.303 ± 0.032	1.471HisThr: 1.471 ± 0.023	1.657HisVal: 1.657 ± 0.02	0.279HisTrp: 0.279 ± 0.008	0.571HisTyr: 0.571 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.084IleAla: 4.084 ± 0.037	0.567IleCys: 0.567 ± 0.012	2.807IleAsp: 2.807 ± 0.027	2.485IleGlu: 2.485 ± 0.027	1.465IlePhe: 1.465 ± 0.023	2.796IleGly: 2.796 ± 0.032	1.084IleHis: 1.084 ± 0.015	1.699IleIle: 1.699 ± 0.024	1.94IleLys: 1.94 ± 0.025	3.656IleLeu: 3.656 ± 0.033	0.73IleMet: 0.73 ± 0.015	1.544IleAsn: 1.544 ± 0.02	2.319IlePro: 2.319 ± 0.025	1.691IleGln: 1.691 ± 0.02	2.549IleArg: 2.549 ± 0.024	3.609IleSer: 3.609 ± 0.029	2.265IleThr: 2.265 ± 0.026	2.78IleVal: 2.78 ± 0.028	0.543IleTrp: 0.543 ± 0.013	1.03IleTyr: 1.03 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.511LysAla: 4.511 ± 0.045	0.395LysCys: 0.395 ± 0.01	2.461LysAsp: 2.461 ± 0.025	2.488LysGlu: 2.488 ± 0.03	1.127LysPhe: 1.127 ± 0.019	2.555LysGly: 2.555 ± 0.034	1.205LysHis: 1.205 ± 0.017	1.791LysIle: 1.791 ± 0.024	2.757LysLys: 2.757 ± 0.038	4.129LysLeu: 4.129 ± 0.034	0.928LysMet: 0.928 ± 0.018	1.391LysAsn: 1.391 ± 0.022	2.556LysPro: 2.556 ± 0.028	2.192LysGln: 2.192 ± 0.023	3.5LysArg: 3.5 ± 0.031	3.454LysSer: 3.454 ± 0.034	2.48LysThr: 2.48 ± 0.029	2.634LysVal: 2.634 ± 0.03	0.516LysTrp: 0.516 ± 0.011	0.974LysTyr: 0.974 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	9.266LeuAla: 9.266 ± 0.056	1.082LeuCys: 1.082 ± 0.02	5.572LeuAsp: 5.572 ± 0.04	5.061LeuGlu: 5.061 ± 0.043	3.035LeuPhe: 3.035 ± 0.032	5.722LeuGly: 5.722 ± 0.042	2.381LeuHis: 2.381 ± 0.024	3.617LeuIle: 3.617 ± 0.034	3.668LeuLys: 3.668 ± 0.036	8.473LeuLeu: 8.473 ± 0.081	1.604LeuMet: 1.604 ± 0.019	2.989LeuAsn: 2.989 ± 0.027	5.669LeuPro: 5.669 ± 0.044	3.953LeuGln: 3.953 ± 0.037	5.761LeuArg: 5.761 ± 0.046	8.354LeuSer: 8.354 ± 0.06	4.887LeuThr: 4.887 ± 0.037	5.6LeuVal: 5.6 ± 0.047	0.964LeuTrp: 0.964 ± 0.016	2.012LeuTyr: 2.012 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.978MetAla: 1.978 ± 0.023	0.2MetCys: 0.2 ± 0.008	1.113MetAsp: 1.113 ± 0.016	0.882MetGlu: 0.882 ± 0.014	0.579MetPhe: 0.579 ± 0.013	1.224MetGly: 1.224 ± 0.018	0.54MetHis: 0.54 ± 0.012	0.798MetIle: 0.798 ± 0.016	0.66MetLys: 0.66 ± 0.015	1.952MetLeu: 1.952 ± 0.021	0.456MetMet: 0.456 ± 0.012	0.567MetAsn: 0.567 ± 0.013	1.242MetPro: 1.242 ± 0.018	0.964MetGln: 0.964 ± 0.02	1.251MetArg: 1.251 ± 0.016	1.929MetSer: 1.929 ± 0.023	1.108MetThr: 1.108 ± 0.017	1.176MetVal: 1.176 ± 0.018	0.23MetTrp: 0.23 ± 0.007	0.413MetTyr: 0.413 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.823AsnAla: 3.823 ± 0.033	0.318AsnCys: 0.318 ± 0.009	1.931AsnAsp: 1.931 ± 0.021	1.689AsnGlu: 1.689 ± 0.022	1.038AsnPhe: 1.038 ± 0.018	2.683AsnGly: 2.683 ± 0.044	0.849AsnHis: 0.849 ± 0.014	1.402AsnIle: 1.402 ± 0.02	1.493AsnLys: 1.493 ± 0.02	2.961AsnLeu: 2.961 ± 0.031	0.663AsnMet: 0.663 ± 0.013	1.231AsnAsn: 1.231 ± 0.026	2.044AsnPro: 2.044 ± 0.027	1.317AsnGln: 1.317 ± 0.02	1.904AsnArg: 1.904 ± 0.02	2.877AsnSer: 2.877 ± 0.031	2.028AsnThr: 2.028 ± 0.026	2.23AsnVal: 2.23 ± 0.024	0.392AsnTrp: 0.392 ± 0.009	0.769AsnTyr: 0.769 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	6.069ProAla: 6.069 ± 0.056	0.51ProCys: 0.51 ± 0.013	2.878ProAsp: 2.878 ± 0.029	2.812ProGlu: 2.812 ± 0.028	1.913ProPhe: 1.913 ± 0.022	3.394ProGly: 3.394 ± 0.041	1.508ProHis: 1.508 ± 0.02	2.355ProIle: 2.355 ± 0.025	2.269ProLys: 2.269 ± 0.027	4.852ProLeu: 4.852 ± 0.037	0.991ProMet: 0.991 ± 0.018	2.053ProAsn: 2.053 ± 0.022	4.787ProPro: 4.787 ± 0.065	2.331ProGln: 2.331 ± 0.035	3.317ProArg: 3.317 ± 0.037	7.299ProSer: 7.299 ± 0.07	4.183ProThr: 4.183 ± 0.037	3.274ProVal: 3.274 ± 0.031	0.59ProTrp: 0.59 ± 0.013	1.258ProTyr: 1.258 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.64GlnAla: 4.64 ± 0.043	0.385GlnCys: 0.385 ± 0.011	2.54GlnAsp: 2.54 ± 0.026	2.309GlnGlu: 2.309 ± 0.026	1.044GlnPhe: 1.044 ± 0.016	2.404GlnGly: 2.404 ± 0.031	1.539GlnHis: 1.539 ± 0.023	1.761GlnIle: 1.761 ± 0.022	1.714GlnLys: 1.714 ± 0.022	4.176GlnLeu: 4.176 ± 0.037	0.903GlnMet: 0.903 ± 0.018	1.398GlnAsn: 1.398 ± 0.021	2.889GlnPro: 2.889 ± 0.041	3.737GlnGln: 3.737 ± 0.101	3.185GlnArg: 3.185 ± 0.03	3.607GlnSer: 3.607 ± 0.03	2.4GlnThr: 2.4 ± 0.022	2.414GlnVal: 2.414 ± 0.025	0.433GlnTrp: 0.433 ± 0.013	0.917GlnTyr: 0.917 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.904ArgAla: 5.904 ± 0.041	0.693ArgCys: 0.693 ± 0.015	3.345ArgAsp: 3.345 ± 0.035	3.257ArgGlu: 3.257 ± 0.037	2.199ArgPhe: 2.199 ± 0.025	3.568ArgGly: 3.568 ± 0.036	1.646ArgHis: 1.646 ± 0.021	2.952ArgIle: 2.952 ± 0.026	3.409ArgLys: 3.409 ± 0.03	5.762ArgLeu: 5.762 ± 0.047	1.296ArgMet: 1.296 ± 0.016	2.217ArgAsn: 2.217 ± 0.023	3.616ArgPro: 3.616 ± 0.036	2.842ArgGln: 2.842 ± 0.027	5.346ArgArg: 5.346 ± 0.047	6.557ArgSer: 6.557 ± 0.055	3.66ArgThr: 3.66 ± 0.031	3.222ArgVal: 3.222 ± 0.03	0.787ArgTrp: 0.787 ± 0.013	1.48ArgTyr: 1.48 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	10.834SerAla: 10.834 ± 0.078	0.938SerCys: 0.938 ± 0.014	5.067SerAsp: 5.067 ± 0.044	4.116SerGlu: 4.116 ± 0.034	3.057SerPhe: 3.057 ± 0.035	6.144SerGly: 6.144 ± 0.051	2.585SerHis: 2.585 ± 0.031	4.205SerIle: 4.205 ± 0.034	4.068SerLys: 4.068 ± 0.037	8.307SerLeu: 8.307 ± 0.055	1.833SerMet: 1.833 ± 0.025	3.69SerAsn: 3.69 ± 0.036	5.945SerPro: 5.945 ± 0.062	3.98SerGln: 3.98 ± 0.037	6.143SerArg: 6.143 ± 0.05	14.181SerSer: 14.181 ± 0.115	7.588SerThr: 7.588 ± 0.059	5.309SerVal: 5.309 ± 0.037	1.001SerTrp: 1.001 ± 0.018	2.012SerTyr: 2.012 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	6.237ThrAla: 6.237 ± 0.047	0.708ThrCys: 0.708 ± 0.016	2.966ThrAsp: 2.966 ± 0.03	2.639ThrGlu: 2.639 ± 0.025	1.971ThrPhe: 1.971 ± 0.023	3.865ThrGly: 3.865 ± 0.038	1.473ThrHis: 1.473 ± 0.021	2.59ThrIle: 2.59 ± 0.027	2.414ThrLys: 2.414 ± 0.031	5.528ThrLeu: 5.528 ± 0.048	1.055ThrMet: 1.055 ± 0.018	2.063ThrAsn: 2.063 ± 0.023	4.347ThrPro: 4.347 ± 0.04	2.232ThrGln: 2.232 ± 0.026	3.45ThrArg: 3.45 ± 0.034	7.065ThrSer: 7.065 ± 0.052	4.171ThrThr: 4.171 ± 0.041	3.364ThrVal: 3.364 ± 0.034	0.673ThrTrp: 0.673 ± 0.012	1.291ThrTyr: 1.291 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.938ValAla: 5.938 ± 0.041	0.717ValCys: 0.717 ± 0.014	3.744ValAsp: 3.744 ± 0.033	3.545ValGlu: 3.545 ± 0.032	1.984ValPhe: 1.984 ± 0.027	3.833ValGly: 3.833 ± 0.035	1.51ValHis: 1.51 ± 0.019	2.404ValIle: 2.404 ± 0.031	2.623ValLys: 2.623 ± 0.028	5.426ValLeu: 5.426 ± 0.044	1.091ValMet: 1.091 ± 0.015	1.877ValAsn: 1.877 ± 0.022	3.347ValPro: 3.347 ± 0.033	2.631ValGln: 2.631 ± 0.023	3.638ValArg: 3.638 ± 0.033	5.132ValSer: 5.132 ± 0.037	3.116ValThr: 3.116 ± 0.03	3.953ValVal: 3.953 ± 0.04	0.743ValTrp: 0.743 ± 0.013	1.421ValTyr: 1.421 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.922TrpAla: 0.922 ± 0.017	0.17TrpCys: 0.17 ± 0.006	0.703TrpAsp: 0.703 ± 0.015	0.539TrpGlu: 0.539 ± 0.012	0.441TrpPhe: 0.441 ± 0.011	0.657TrpGly: 0.657 ± 0.014	0.307TrpHis: 0.307 ± 0.01	0.665TrpIle: 0.665 ± 0.014	0.611TrpLys: 0.611 ± 0.013	1.21TrpLeu: 1.21 ± 0.02	0.289TrpMet: 0.289 ± 0.009	0.533TrpAsn: 0.533 ± 0.013	0.524TrpPro: 0.524 ± 0.013	0.559TrpGln: 0.559 ± 0.013	0.761TrpArg: 0.761 ± 0.016	1.114TrpSer: 1.114 ± 0.018	0.773TrpThr: 0.773 ± 0.013	0.571TrpVal: 0.571 ± 0.013	0.215TrpTrp: 0.215 ± 0.008	0.311TrpTyr: 0.311 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.155TyrAla: 2.155 ± 0.02	0.292TyrCys: 0.292 ± 0.009	1.448TyrAsp: 1.448 ± 0.021	1.155TyrGlu: 1.155 ± 0.018	0.875TyrPhe: 0.875 ± 0.016	1.633TyrGly: 1.633 ± 0.025	0.639TyrHis: 0.639 ± 0.012	1.003TyrIle: 1.003 ± 0.016	0.864TyrLys: 0.864 ± 0.015	2.216TyrLeu: 2.216 ± 0.024	0.443TyrMet: 0.443 ± 0.012	0.814TyrAsn: 0.814 ± 0.016	1.169TyrPro: 1.169 ± 0.021	0.909TyrGln: 0.909 ± 0.017	1.463TyrArg: 1.463 ± 0.021	1.833TyrSer: 1.833 ± 0.023	1.327TyrThr: 1.327 ± 0.019	1.359TyrVal: 1.359 ± 0.02	0.297TyrTrp: 0.297 ± 0.009	0.652TyrTyr: 0.652 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6806 proteins (4006347 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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