Amino acid dipepetide frequency for Marvinbryantia formatexigens DSM 14469

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.418AlaAla: 9.418 ± 0.112	1.251AlaCys: 1.251 ± 0.029	5.216AlaAsp: 5.216 ± 0.062	6.57AlaGlu: 6.57 ± 0.088	3.145AlaPhe: 3.145 ± 0.053	7.506AlaGly: 7.506 ± 0.082	1.215AlaHis: 1.215 ± 0.032	4.577AlaIle: 4.577 ± 0.069	4.345AlaLys: 4.345 ± 0.062	7.614AlaLeu: 7.614 ± 0.087	2.511AlaMet: 2.511 ± 0.048	2.362AlaAsn: 2.362 ± 0.042	2.331AlaPro: 2.331 ± 0.041	3.021AlaGln: 3.021 ± 0.058	3.451AlaArg: 3.451 ± 0.058	4.138AlaSer: 4.138 ± 0.057	3.128AlaThr: 3.128 ± 0.064	6.858AlaVal: 6.858 ± 0.077	0.804AlaTrp: 0.804 ± 0.024	2.964AlaTyr: 2.964 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.231CysAla: 1.231 ± 0.032	0.346CysCys: 0.346 ± 0.015	0.911CysAsp: 0.911 ± 0.03	0.939CysGlu: 0.939 ± 0.027	0.777CysPhe: 0.777 ± 0.024	1.656CysGly: 1.656 ± 0.037	0.335CysHis: 0.335 ± 0.016	1.117CysIle: 1.117 ± 0.029	0.667CysLys: 0.667 ± 0.021	1.247CysLeu: 1.247 ± 0.034	0.538CysMet: 0.538 ± 0.021	0.575CysAsn: 0.575 ± 0.022	0.662CysPro: 0.662 ± 0.026	0.453CysGln: 0.453 ± 0.019	1.157CysArg: 1.157 ± 0.034	0.995CysSer: 0.995 ± 0.025	0.826CysThr: 0.826 ± 0.026	1.034CysVal: 1.034 ± 0.03	0.15CysTrp: 0.15 ± 0.01	0.597CysTyr: 0.597 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.615AspAla: 4.615 ± 0.062	0.912AspCys: 0.912 ± 0.027	2.601AspAsp: 2.601 ± 0.055	4.266AspGlu: 4.266 ± 0.064	2.598AspPhe: 2.598 ± 0.048	4.865AspGly: 4.865 ± 0.077	0.649AspHis: 0.649 ± 0.027	4.26AspIle: 4.26 ± 0.058	2.907AspLys: 2.907 ± 0.048	3.747AspLeu: 3.747 ± 0.05	1.879AspMet: 1.879 ± 0.037	2.018AspAsn: 2.018 ± 0.039	1.481AspPro: 1.481 ± 0.036	0.948AspGln: 0.948 ± 0.031	2.44AspArg: 2.44 ± 0.047	2.93AspSer: 2.93 ± 0.049	3.3AspThr: 3.3 ± 0.061	3.567AspVal: 3.567 ± 0.049	0.64AspTrp: 0.64 ± 0.022	2.663AspTyr: 2.663 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	6.354GluAla: 6.354 ± 0.091	0.862GluCys: 0.862 ± 0.025	4.006GluAsp: 4.006 ± 0.07	7.472GluGlu: 7.472 ± 0.104	2.403GluPhe: 2.403 ± 0.043	4.463GluGly: 4.463 ± 0.064	1.404GluHis: 1.404 ± 0.034	5.236GluIle: 5.236 ± 0.066	6.567GluLys: 6.567 ± 0.081	6.778GluLeu: 6.778 ± 0.085	2.415GluMet: 2.415 ± 0.045	4.249GluAsn: 4.249 ± 0.058	2.126GluPro: 2.126 ± 0.053	3.102GluGln: 3.102 ± 0.056	3.835GluArg: 3.835 ± 0.061	3.343GluSer: 3.343 ± 0.052	4.561GluThr: 4.561 ± 0.079	4.156GluVal: 4.156 ± 0.058	0.785GluTrp: 0.785 ± 0.024	3.081GluTyr: 3.081 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.38PheAla: 3.38 ± 0.052	0.926PheCys: 0.926 ± 0.026	2.282PheAsp: 2.282 ± 0.039	2.475PheGlu: 2.475 ± 0.038	1.944PhePhe: 1.944 ± 0.046	2.969PheGly: 2.969 ± 0.057	0.81PheHis: 0.81 ± 0.025	2.54PheIle: 2.54 ± 0.042	1.646PheLys: 1.646 ± 0.035	4.161PheLeu: 4.161 ± 0.065	1.197PheMet: 1.197 ± 0.029	1.309PheAsn: 1.309 ± 0.029	1.507PhePro: 1.507 ± 0.036	1.326PheGln: 1.326 ± 0.03	2.043PheArg: 2.043 ± 0.039	3.058PheSer: 3.058 ± 0.049	2.343PheThr: 2.343 ± 0.045	2.765PheVal: 2.765 ± 0.047	0.464PheTrp: 0.464 ± 0.018	1.876PheTyr: 1.876 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	5.636GlyAla: 5.636 ± 0.084	1.342GlyCys: 1.342 ± 0.034	3.446GlyAsp: 3.446 ± 0.05	5.11GlyGlu: 5.11 ± 0.072	3.084GlyPhe: 3.084 ± 0.049	5.333GlyGly: 5.333 ± 0.093	1.17GlyHis: 1.17 ± 0.026	6.021GlyIle: 6.021 ± 0.078	5.255GlyLys: 5.255 ± 0.062	5.587GlyLeu: 5.587 ± 0.085	2.642GlyMet: 2.642 ± 0.047	3.141GlyAsn: 3.141 ± 0.053	1.282GlyPro: 1.282 ± 0.033	2.398GlyGln: 2.398 ± 0.045	3.787GlyArg: 3.787 ± 0.05	4.25GlySer: 4.25 ± 0.069	4.572GlyThr: 4.572 ± 0.097	4.954GlyVal: 4.954 ± 0.066	0.823GlyTrp: 0.823 ± 0.024	3.329GlyTyr: 3.329 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.151HisAla: 1.151 ± 0.03	0.297HisCys: 0.297 ± 0.017	0.855HisAsp: 0.855 ± 0.029	1.039HisGlu: 1.039 ± 0.029	0.869HisPhe: 0.869 ± 0.026	1.335HisGly: 1.335 ± 0.031	0.399HisHis: 0.399 ± 0.021	1.345HisIle: 1.345 ± 0.033	0.785HisLys: 0.785 ± 0.026	1.458HisLeu: 1.458 ± 0.035	0.553HisMet: 0.553 ± 0.021	0.656HisAsn: 0.656 ± 0.021	0.939HisPro: 0.939 ± 0.024	0.489HisGln: 0.489 ± 0.017	0.88HisArg: 0.88 ± 0.026	0.945HisSer: 0.945 ± 0.028	0.998HisThr: 0.998 ± 0.027	1.031HisVal: 1.031 ± 0.029	0.187HisTrp: 0.187 ± 0.013	0.78HisTyr: 0.78 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.653IleAla: 5.653 ± 0.062	1.427IleCys: 1.427 ± 0.032	3.459IleAsp: 3.459 ± 0.059	4.098IleGlu: 4.098 ± 0.059	3.019IlePhe: 3.019 ± 0.054	4.583IleGly: 4.583 ± 0.061	1.209IleHis: 1.209 ± 0.033	4.48IleIle: 4.48 ± 0.067	3.277IleLys: 3.277 ± 0.058	6.685IleLeu: 6.685 ± 0.089	1.929IleMet: 1.929 ± 0.04	2.483IleAsn: 2.483 ± 0.045	2.963IlePro: 2.963 ± 0.05	2.087IleGln: 2.087 ± 0.038	4.071IleArg: 4.071 ± 0.058	4.691IleSer: 4.691 ± 0.064	3.94IleThr: 3.94 ± 0.063	4.364IleVal: 4.364 ± 0.069	0.691IleTrp: 0.691 ± 0.023	2.72IleTyr: 2.72 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.47LysAla: 4.47 ± 0.062	0.726LysCys: 0.726 ± 0.026	3.107LysAsp: 3.107 ± 0.054	5.617LysGlu: 5.617 ± 0.068	1.672LysPhe: 1.672 ± 0.038	3.672LysGly: 3.672 ± 0.053	0.934LysHis: 0.934 ± 0.026	4.148LysIle: 4.148 ± 0.057	5.54LysLys: 5.54 ± 0.076	4.844LysLeu: 4.844 ± 0.069	2.022LysMet: 2.022 ± 0.041	3.267LysAsn: 3.267 ± 0.051	1.884LysPro: 1.884 ± 0.038	2.156LysGln: 2.156 ± 0.04	3.185LysArg: 3.185 ± 0.048	3.084LysSer: 3.084 ± 0.051	3.659LysThr: 3.659 ± 0.057	3.387LysVal: 3.387 ± 0.051	0.626LysTrp: 0.626 ± 0.018	2.591LysTyr: 2.591 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	7.572LeuAla: 7.572 ± 0.088	1.679LeuCys: 1.679 ± 0.037	4.669LeuAsp: 4.669 ± 0.062	6.391LeuGlu: 6.391 ± 0.073	3.883LeuPhe: 3.883 ± 0.065	5.504LeuGly: 5.504 ± 0.074	1.574LeuHis: 1.574 ± 0.034	5.527LeuIle: 5.527 ± 0.076	5.332LeuLys: 5.332 ± 0.079	9.373LeuLeu: 9.373 ± 0.119	2.606LeuMet: 2.606 ± 0.046	3.225LeuAsn: 3.225 ± 0.043	3.945LeuPro: 3.945 ± 0.058	3.285LeuGln: 3.285 ± 0.048	4.389LeuArg: 4.389 ± 0.068	5.975LeuSer: 5.975 ± 0.073	5.236LeuThr: 5.236 ± 0.074	5.452LeuVal: 5.452 ± 0.078	0.848LeuTrp: 0.848 ± 0.029	3.486LeuTyr: 3.486 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.498MetAla: 2.498 ± 0.043	0.377MetCys: 0.377 ± 0.017	1.737MetAsp: 1.737 ± 0.04	2.737MetGlu: 2.737 ± 0.047	1.028MetPhe: 1.028 ± 0.028	1.99MetGly: 1.99 ± 0.043	0.478MetHis: 0.478 ± 0.018	2.028MetIle: 2.028 ± 0.034	2.451MetLys: 2.451 ± 0.04	3.017MetLeu: 3.017 ± 0.056	1.022MetMet: 1.022 ± 0.031	1.416MetAsn: 1.416 ± 0.03	1.277MetPro: 1.277 ± 0.032	1.285MetGln: 1.285 ± 0.03	1.487MetArg: 1.487 ± 0.03	1.684MetSer: 1.684 ± 0.034	1.838MetThr: 1.838 ± 0.042	1.898MetVal: 1.898 ± 0.042	0.259MetTrp: 0.259 ± 0.015	0.942MetTyr: 0.942 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.115AsnAla: 3.115 ± 0.053	0.581AsnCys: 0.581 ± 0.022	1.81AsnAsp: 1.81 ± 0.04	2.492AsnGlu: 2.492 ± 0.045	1.48AsnPhe: 1.48 ± 0.03	3.466AsnGly: 3.466 ± 0.063	0.778AsnHis: 0.778 ± 0.026	2.971AsnIle: 2.971 ± 0.048	1.946AsnLys: 1.946 ± 0.041	3.628AsnLeu: 3.628 ± 0.054	1.317AsnMet: 1.317 ± 0.029	1.532AsnAsn: 1.532 ± 0.039	1.924AsnPro: 1.924 ± 0.041	1.256AsnGln: 1.256 ± 0.027	2.167AsnArg: 2.167 ± 0.039	2.111AsnSer: 2.111 ± 0.044	2.181AsnThr: 2.181 ± 0.042	2.553AsnVal: 2.553 ± 0.048	0.453AsnTrp: 0.453 ± 0.018	1.752AsnTyr: 1.752 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	2.992ProAla: 2.992 ± 0.055	0.507ProCys: 0.507 ± 0.019	2.411ProAsp: 2.411 ± 0.053	3.793ProGlu: 3.793 ± 0.062	1.527ProPhe: 1.527 ± 0.029	2.624ProGly: 2.624 ± 0.05	0.619ProHis: 0.619 ± 0.021	1.578ProIle: 1.578 ± 0.038	1.527ProLys: 1.527 ± 0.036	2.844ProLeu: 2.844 ± 0.053	0.881ProMet: 0.881 ± 0.023	0.943ProAsn: 0.943 ± 0.027	0.844ProPro: 0.844 ± 0.027	1.342ProGln: 1.342 ± 0.034	1.135ProArg: 1.135 ± 0.029	1.709ProSer: 1.709 ± 0.04	1.44ProThr: 1.44 ± 0.04	3.321ProVal: 3.321 ± 0.056	0.331ProTrp: 0.331 ± 0.015	1.525ProTyr: 1.525 ± 0.046	0.0ProXaa: 0.0 ± 0.0
Gln	2.681GlnAla: 2.681 ± 0.053	0.397GlnCys: 0.397 ± 0.017	1.468GlnAsp: 1.468 ± 0.032	3.143GlnGlu: 3.143 ± 0.046	1.168GlnPhe: 1.168 ± 0.028	2.029GlnGly: 2.029 ± 0.035	0.485GlnHis: 0.485 ± 0.019	2.607GlnIle: 2.607 ± 0.049	2.898GlnLys: 2.898 ± 0.05	2.697GlnLeu: 2.697 ± 0.054	1.301GlnMet: 1.301 ± 0.03	1.501GlnAsn: 1.501 ± 0.036	1.105GlnPro: 1.105 ± 0.034	1.399GlnGln: 1.399 ± 0.037	1.701GlnArg: 1.701 ± 0.044	1.83GlnSer: 1.83 ± 0.036	2.093GlnThr: 2.093 ± 0.05	2.022GlnVal: 2.022 ± 0.039	0.332GlnTrp: 0.332 ± 0.016	1.435GlnTyr: 1.435 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	3.464ArgAla: 3.464 ± 0.06	0.752ArgCys: 0.752 ± 0.027	2.401ArgAsp: 2.401 ± 0.05	4.466ArgGlu: 4.466 ± 0.071	2.026ArgPhe: 2.026 ± 0.038	2.901ArgGly: 2.901 ± 0.047	0.959ArgHis: 0.959 ± 0.028	3.786ArgIle: 3.786 ± 0.064	3.769ArgLys: 3.769 ± 0.059	4.557ArgLeu: 4.557 ± 0.061	1.819ArgMet: 1.819 ± 0.038	2.121ArgAsn: 2.121 ± 0.039	1.421ArgPro: 1.421 ± 0.038	2.154ArgGln: 2.154 ± 0.043	3.364ArgArg: 3.364 ± 0.063	2.447ArgSer: 2.447 ± 0.045	2.621ArgThr: 2.621 ± 0.044	2.913ArgVal: 2.913 ± 0.051	0.498ArgTrp: 0.498 ± 0.019	2.159ArgTyr: 2.159 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.806SerAla: 4.806 ± 0.069	0.873SerCys: 0.873 ± 0.023	3.116SerAsp: 3.116 ± 0.05	3.813SerGlu: 3.813 ± 0.064	2.809SerPhe: 2.809 ± 0.055	5.508SerGly: 5.508 ± 0.094	0.94SerHis: 0.94 ± 0.029	3.673SerIle: 3.673 ± 0.066	2.409SerLys: 2.409 ± 0.041	5.05SerLeu: 5.05 ± 0.064	1.805SerMet: 1.805 ± 0.037	1.91SerAsn: 1.91 ± 0.042	1.769SerPro: 1.769 ± 0.035	1.768SerGln: 1.768 ± 0.038	3.06SerArg: 3.06 ± 0.05	3.381SerSer: 3.381 ± 0.056	2.712SerThr: 2.712 ± 0.045	4.383SerVal: 4.383 ± 0.063	0.64SerTrp: 0.64 ± 0.022	2.396SerTyr: 2.396 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.096ThrAla: 5.096 ± 0.073	0.754ThrCys: 0.754 ± 0.025	3.498ThrAsp: 3.498 ± 0.067	4.774ThrGlu: 4.774 ± 0.118	2.139ThrPhe: 2.139 ± 0.042	5.122ThrGly: 5.122 ± 0.072	0.843ThrHis: 0.843 ± 0.025	3.603ThrIle: 3.603 ± 0.055	2.637ThrLys: 2.637 ± 0.044	4.936ThrLeu: 4.936 ± 0.064	1.485ThrMet: 1.485 ± 0.031	1.78ThrAsn: 1.78 ± 0.039	2.065ThrPro: 2.065 ± 0.041	1.679ThrGln: 1.679 ± 0.036	2.095ThrArg: 2.095 ± 0.041	2.711ThrSer: 2.711 ± 0.054	2.663ThrThr: 2.663 ± 0.052	4.89ThrVal: 4.89 ± 0.08	0.596ThrTrp: 0.596 ± 0.02	2.077ThrTyr: 2.077 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.621ValAla: 4.621 ± 0.067	1.345ValCys: 1.345 ± 0.029	3.292ValAsp: 3.292 ± 0.046	4.322ValGlu: 4.322 ± 0.069	3.119ValPhe: 3.119 ± 0.054	3.875ValGly: 3.875 ± 0.059	1.057ValHis: 1.057 ± 0.027	4.878ValIle: 4.878 ± 0.066	3.932ValLys: 3.932 ± 0.058	6.771ValLeu: 6.771 ± 0.091	2.033ValMet: 2.033 ± 0.039	2.701ValAsn: 2.701 ± 0.05	2.67ValPro: 2.67 ± 0.048	2.172ValGln: 2.172 ± 0.046	3.341ValArg: 3.341 ± 0.046	4.69ValSer: 4.69 ± 0.065	4.338ValThr: 4.338 ± 0.076	4.392ValVal: 4.392 ± 0.065	0.772ValTrp: 0.772 ± 0.026	2.808ValTyr: 2.808 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.646TrpAla: 0.646 ± 0.023	0.173TrpCys: 0.173 ± 0.011	0.595TrpAsp: 0.595 ± 0.023	0.813TrpGlu: 0.813 ± 0.026	0.43TrpPhe: 0.43 ± 0.017	0.699TrpGly: 0.699 ± 0.024	0.202TrpHis: 0.202 ± 0.014	0.743TrpIle: 0.743 ± 0.024	0.784TrpLys: 0.784 ± 0.024	0.971TrpLeu: 0.971 ± 0.029	0.338TrpMet: 0.338 ± 0.016	0.576TrpAsn: 0.576 ± 0.023	0.202TrpPro: 0.202 ± 0.013	0.491TrpGln: 0.491 ± 0.017	0.515TrpArg: 0.515 ± 0.018	0.578TrpSer: 0.578 ± 0.021	0.551TrpThr: 0.551 ± 0.025	0.519TrpVal: 0.519 ± 0.019	0.133TrpTrp: 0.133 ± 0.011	0.5TrpTyr: 0.5 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.026TyrAla: 3.026 ± 0.048	0.686TyrCys: 0.686 ± 0.022	2.406TyrAsp: 2.406 ± 0.047	2.868TyrGlu: 2.868 ± 0.051	1.9TyrPhe: 1.9 ± 0.034	3.064TyrGly: 3.064 ± 0.053	0.932TyrHis: 0.932 ± 0.027	2.712TyrIle: 2.712 ± 0.04	1.918TyrLys: 1.918 ± 0.042	3.984TyrLeu: 3.984 ± 0.064	1.155TyrMet: 1.155 ± 0.031	1.746TyrAsn: 1.746 ± 0.031	1.498TyrPro: 1.498 ± 0.035	1.484TyrGln: 1.484 ± 0.038	2.492TyrArg: 2.492 ± 0.05	2.272TyrSer: 2.272 ± 0.04	2.44TyrThr: 2.44 ± 0.046	2.672TyrVal: 2.672 ± 0.047	0.425TyrTrp: 0.425 ± 0.019	2.049TyrTyr: 2.049 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4894 proteins (1389242 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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