Amino acid dipepetide frequency for Erve virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.11AlaAla: 3.11 ± 1.141
1.382AlaCys: 1.382 ± 0.408
1.382AlaAsp: 1.382 ± 0.502
2.246AlaGlu: 2.246 ± 0.429
1.728AlaPhe: 1.728 ± 0.41
2.073AlaGly: 2.073 ± 0.279
0.518AlaHis: 0.518 ± 0.279
2.419AlaIle: 2.419 ± 0.317
3.801AlaLys: 3.801 ± 0.509
4.147AlaLeu: 4.147 ± 1.367
1.209AlaMet: 1.209 ± 0.469
3.11AlaAsn: 3.11 ± 0.621
1.555AlaPro: 1.555 ± 0.623
1.728AlaGln: 1.728 ± 1.321
1.9AlaArg: 1.9 ± 1.029
3.974AlaSer: 3.974 ± 0.425
2.246AlaThr: 2.246 ± 0.815
3.801AlaVal: 3.801 ± 1.042
1.037AlaTrp: 1.037 ± 0.425
1.382AlaTyr: 1.382 ± 0.554
0.0AlaXaa: 0.0 ± 0.0
Cys
1.209CysAla: 1.209 ± 0.158
1.555CysCys: 1.555 ± 0.006
0.518CysAsp: 0.518 ± 0.7
1.382CysGlu: 1.382 ± 0.243
1.728CysPhe: 1.728 ± 0.093
1.382CysGly: 1.382 ± 0.619
0.864CysHis: 0.864 ± 0.246
2.073CysIle: 2.073 ± 0.547
2.592CysLys: 2.592 ± 1.924
2.592CysLeu: 2.592 ± 0.739
0.346CysMet: 0.346 ± 0.186
1.037CysAsn: 1.037 ± 0.464
1.728CysPro: 1.728 ± 1.076
0.864CysGln: 0.864 ± 0.465
1.9CysArg: 1.9 ± 0.462
1.728CysSer: 1.728 ± 0.774
2.073CysThr: 2.073 ± 1.539
0.691CysVal: 0.691 ± 0.194
0.518CysTrp: 0.518 ± 0.385
0.346CysTyr: 0.346 ± 0.467
0.0CysXaa: 0.0 ± 0.0
Asp
1.555AspAla: 1.555 ± 0.314
2.246AspCys: 2.246 ± 0.59
2.592AspAsp: 2.592 ± 1.096
2.764AspGlu: 2.764 ± 1.188
1.9AspPhe: 1.9 ± 0.366
3.283AspGly: 3.283 ± 0.745
1.382AspHis: 1.382 ± 0.452
4.147AspIle: 4.147 ± 0.707
3.628AspLys: 3.628 ± 0.778
4.665AspLeu: 4.665 ± 0.644
0.691AspMet: 0.691 ± 0.187
2.073AspAsn: 2.073 ± 1.116
2.073AspPro: 2.073 ± 0.218
1.9AspGln: 1.9 ± 0.704
2.246AspArg: 2.246 ± 0.255
3.455AspSer: 3.455 ± 1.14
1.9AspThr: 1.9 ± 0.186
3.974AspVal: 3.974 ± 0.373
0.518AspTrp: 0.518 ± 0.279
1.555AspTyr: 1.555 ± 0.006
0.0AspXaa: 0.0 ± 0.0
Glu
3.455GluAla: 3.455 ± 0.968
1.209GluCys: 1.209 ± 0.692
3.11GluAsp: 3.11 ± 0.547
6.565GluGlu: 6.565 ± 0.453
2.937GluPhe: 2.937 ± 0.735
4.319GluGly: 4.319 ± 1.181
1.382GluHis: 1.382 ± 0.577
2.937GluIle: 2.937 ± 1.052
3.455GluLys: 3.455 ± 0.459
5.701GluLeu: 5.701 ± 0.43
1.728GluMet: 1.728 ± 1.071
1.9GluAsn: 1.9 ± 0.501
2.246GluPro: 2.246 ± 0.402
2.419GluGln: 2.419 ± 0.95
3.283GluArg: 3.283 ± 0.093
5.701GluSer: 5.701 ± 1.184
5.01GluThr: 5.01 ± 0.757
6.22GluVal: 6.22 ± 1.242
0.864GluTrp: 0.864 ± 0.372
1.209GluTyr: 1.209 ± 0.398
0.0GluXaa: 0.0 ± 0.0
Phe
1.728PheAla: 1.728 ± 0.626
0.173PheCys: 0.173 ± 0.233
2.246PheAsp: 2.246 ± 0.855
3.11PheGlu: 3.11 ± 0.643
2.592PhePhe: 2.592 ± 0.518
2.419PheGly: 2.419 ± 0.373
1.037PheHis: 1.037 ± 0.59
2.764PheIle: 2.764 ± 1.188
3.628PheLys: 3.628 ± 0.281
4.838PheLeu: 4.838 ± 0.632
1.382PheMet: 1.382 ± 0.452
1.9PheAsn: 1.9 ± 0.726
1.555PhePro: 1.555 ± 0.314
2.246PheGln: 2.246 ± 0.774
0.864PheArg: 0.864 ± 0.19
4.838PheSer: 4.838 ± 0.732
2.419PheThr: 2.419 ± 0.796
2.073PheVal: 2.073 ± 0.414
0.173PheTrp: 0.173 ± 0.093
1.382PheTyr: 1.382 ± 0.243
0.0PheXaa: 0.0 ± 0.0
Gly
1.209GlyAla: 1.209 ± 0.926
1.728GlyCys: 1.728 ± 0.774
2.592GlyAsp: 2.592 ± 0.461
3.283GlyGlu: 3.283 ± 0.488
2.764GlyPhe: 2.764 ± 1.454
3.455GlyGly: 3.455 ± 1.454
0.864GlyHis: 0.864 ± 0.19
2.592GlyIle: 2.592 ± 0.38
4.319GlyLys: 4.319 ± 0.194
6.911GlyLeu: 6.911 ± 0.517
1.209GlyMet: 1.209 ± 0.499
2.764GlyAsn: 2.764 ± 0.73
1.9GlyPro: 1.9 ± 1.191
1.037GlyGln: 1.037 ± 0.425
3.11GlyArg: 3.11 ± 0.547
5.356GlySer: 5.356 ± 1.088
2.419GlyThr: 2.419 ± 0.848
3.11GlyVal: 3.11 ± 0.317
0.173GlyTrp: 0.173 ± 0.093
2.073GlyTyr: 2.073 ± 1.098
0.0GlyXaa: 0.0 ± 0.0
His
2.073HisAla: 2.073 ± 0.818
0.691HisCys: 0.691 ± 0.617
0.346HisAsp: 0.346 ± 0.186
1.555HisGlu: 1.555 ± 0.305
1.555HisPhe: 1.555 ± 0.638
0.691HisGly: 0.691 ± 0.933
0.691HisHis: 0.691 ± 0.617
0.691HisIle: 0.691 ± 0.372
1.209HisLys: 1.209 ± 0.186
3.11HisLeu: 3.11 ± 0.012
1.037HisMet: 1.037 ± 0.109
1.037HisAsn: 1.037 ± 0.558
1.037HisPro: 1.037 ± 0.425
1.382HisGln: 1.382 ± 0.694
0.864HisArg: 0.864 ± 0.19
1.382HisSer: 1.382 ± 0.923
0.518HisThr: 0.518 ± 0.104
1.555HisVal: 1.555 ± 0.006
0.173HisTrp: 0.173 ± 0.093
0.691HisTyr: 0.691 ± 0.372
0.0HisXaa: 0.0 ± 0.0
Ile
2.592IleAla: 2.592 ± 1.299
2.246IleCys: 2.246 ± 0.424
3.11IleAsp: 3.11 ± 0.643
5.01IleGlu: 5.01 ± 1.063
2.592IlePhe: 2.592 ± 0.57
2.937IleGly: 2.937 ± 0.45
1.209IleHis: 1.209 ± 0.333
5.183IleIle: 5.183 ± 0.377
7.602IleLys: 7.602 ± 1.264
6.22IleLeu: 6.22 ± 0.965
1.037IleMet: 1.037 ± 0.279
2.937IleAsn: 2.937 ± 0.875
2.592IlePro: 2.592 ± 0.657
2.073IleGln: 2.073 ± 0.218
3.455IleArg: 3.455 ± 0.459
5.701IleSer: 5.701 ± 1.636
3.455IleThr: 3.455 ± 0.702
4.147IleVal: 4.147 ± 0.196
0.346IleTrp: 0.346 ± 0.186
1.728IleTyr: 1.728 ± 0.93
0.0IleXaa: 0.0 ± 0.0
Lys
3.11LysAla: 3.11 ± 0.838
1.555LysCys: 1.555 ± 0.311
4.319LysAsp: 4.319 ± 0.358
5.183LysGlu: 5.183 ± 1.359
3.11LysPhe: 3.11 ± 0.541
4.147LysGly: 4.147 ± 1.396
1.9LysHis: 1.9 ± 0.445
4.147LysIle: 4.147 ± 0.281
5.183LysLys: 5.183 ± 0.278
9.157LysLeu: 9.157 ± 2.086
1.382LysMet: 1.382 ± 0.263
4.492LysAsn: 4.492 ± 0.815
2.419LysPro: 2.419 ± 0.682
3.455LysGln: 3.455 ± 0.998
3.11LysArg: 3.11 ± 0.327
6.565LysSer: 6.565 ± 1.558
4.492LysThr: 4.492 ± 0.644
3.628LysVal: 3.628 ± 0.408
1.555LysTrp: 1.555 ± 0.958
2.419LysTyr: 2.419 ± 0.494
0.0LysXaa: 0.0 ± 0.0
Leu
3.628LeuAla: 3.628 ± 1.115
3.11LeuCys: 3.11 ± 0.843
5.529LeuAsp: 5.529 ± 1.259
5.874LeuGlu: 5.874 ± 0.492
4.665LeuPhe: 4.665 ± 0.555
5.356LeuGly: 5.356 ± 0.927
2.073LeuHis: 2.073 ± 0.365
6.393LeuIle: 6.393 ± 0.479
8.984LeuLys: 8.984 ± 1.726
12.267LeuLeu: 12.267 ± 1.445
3.455LeuMet: 3.455 ± 0.809
4.838LeuAsn: 4.838 ± 0.732
3.283LeuPro: 3.283 ± 0.633
2.937LeuGln: 2.937 ± 0.238
4.492LeuArg: 4.492 ± 0.877
12.094LeuSer: 12.094 ± 0.703
8.811LeuThr: 8.811 ± 1.986
6.565LeuVal: 6.565 ± 0.653
0.691LeuTrp: 0.691 ± 0.309
3.283LeuTyr: 3.283 ± 0.377
0.0LeuXaa: 0.0 ± 0.0
Met
1.209MetAla: 1.209 ± 0.333
0.0MetCys: 0.0 ± 0.0
1.382MetAsp: 1.382 ± 0.408
1.555MetGlu: 1.555 ± 0.322
0.691MetPhe: 0.691 ± 0.122
1.209MetGly: 1.209 ± 0.87
0.518MetHis: 0.518 ± 0.276
2.246MetIle: 2.246 ± 0.809
1.209MetLys: 1.209 ± 0.398
2.592MetLeu: 2.592 ± 0.868
1.037MetMet: 1.037 ± 0.273
1.9MetAsn: 1.9 ± 0.406
0.346MetPro: 0.346 ± 0.155
0.691MetGln: 0.691 ± 0.251
0.691MetArg: 0.691 ± 0.372
1.382MetSer: 1.382 ± 0.408
0.691MetThr: 0.691 ± 0.194
1.209MetVal: 1.209 ± 0.468
0.346MetTrp: 0.346 ± 0.212
0.691MetTyr: 0.691 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
2.073AsnAla: 2.073 ± 1.098
1.209AsnCys: 1.209 ± 0.206
3.11AsnAsp: 3.11 ± 1.085
1.728AsnGlu: 1.728 ± 0.41
1.9AsnPhe: 1.9 ± 0.819
1.728AsnGly: 1.728 ± 0.999
1.728AsnHis: 1.728 ± 0.634
2.419AsnIle: 2.419 ± 0.187
5.01AsnLys: 5.01 ± 0.435
5.701AsnLeu: 5.701 ± 0.281
0.691AsnMet: 0.691 ± 0.372
2.073AsnAsn: 2.073 ± 0.365
1.728AsnPro: 1.728 ± 0.253
1.9AsnGln: 1.9 ± 0.186
3.11AsnArg: 3.11 ± 1.374
5.529AsnSer: 5.529 ± 1.302
1.728AsnThr: 1.728 ± 0.38
3.283AsnVal: 3.283 ± 1.237
1.382AsnTrp: 1.382 ± 0.236
2.592AsnTyr: 2.592 ± 0.59
0.0AsnXaa: 0.0 ± 0.0
Pro
2.246ProAla: 2.246 ± 0.876
0.864ProCys: 0.864 ± 0.538
1.728ProAsp: 1.728 ± 0.253
3.283ProGlu: 3.283 ± 0.457
0.691ProPhe: 0.691 ± 0.122
1.209ProGly: 1.209 ± 0.817
0.691ProHis: 0.691 ± 0.372
1.382ProIle: 1.382 ± 0.236
2.937ProLys: 2.937 ± 0.391
2.073ProLeu: 2.073 ± 0.279
1.382ProMet: 1.382 ± 0.554
1.9ProAsn: 1.9 ± 0.705
0.691ProPro: 0.691 ± 0.502
1.382ProGln: 1.382 ± 0.387
1.209ProArg: 1.209 ± 0.206
3.455ProSer: 3.455 ± 0.411
1.728ProThr: 1.728 ± 1.68
1.209ProVal: 1.209 ± 0.692
0.691ProTrp: 0.691 ± 0.465
1.037ProTyr: 1.037 ± 0.464
0.0ProXaa: 0.0 ± 0.0
Gln
2.592GlnAla: 2.592 ± 0.431
0.691GlnCys: 0.691 ± 0.309
1.728GlnAsp: 1.728 ± 0.41
3.11GlnGlu: 3.11 ± 1.091
1.037GlnPhe: 1.037 ± 0.109
1.555GlnGly: 1.555 ± 0.006
1.209GlnHis: 1.209 ± 0.158
3.11GlnIle: 3.11 ± 0.627
1.209GlnLys: 1.209 ± 0.158
4.665GlnLeu: 4.665 ± 1.129
1.209GlnMet: 1.209 ± 0.456
2.592GlnAsn: 2.592 ± 0.822
0.518GlnPro: 0.518 ± 0.276
2.073GlnGln: 2.073 ± 0.457
1.728GlnArg: 1.728 ± 0.355
2.764GlnSer: 2.764 ± 0.93
2.764GlnThr: 2.764 ± 0.471
1.728GlnVal: 1.728 ± 0.828
0.173GlnTrp: 0.173 ± 0.248
0.864GlnTyr: 0.864 ± 0.433
0.0GlnXaa: 0.0 ± 0.0
Arg
2.246ArgAla: 2.246 ± 0.815
1.209ArgCys: 1.209 ± 0.158
2.764ArgAsp: 2.764 ± 0.789
2.937ArgGlu: 2.937 ± 0.629
2.246ArgPhe: 2.246 ± 0.634
1.555ArgGly: 1.555 ± 1.125
0.518ArgHis: 0.518 ± 0.104
2.937ArgIle: 2.937 ± 0.556
2.246ArgLys: 2.246 ± 0.372
7.084ArgLeu: 7.084 ± 1.261
0.691ArgMet: 0.691 ± 0.309
1.555ArgAsn: 1.555 ± 0.543
1.209ArgPro: 1.209 ± 0.398
2.246ArgGln: 2.246 ± 0.563
2.937ArgArg: 2.937 ± 0.32
5.01ArgSer: 5.01 ± 0.724
1.728ArgThr: 1.728 ± 0.558
1.728ArgVal: 1.728 ± 0.231
0.346ArgTrp: 0.346 ± 0.212
1.728ArgTyr: 1.728 ± 0.93
0.0ArgXaa: 0.0 ± 0.0
Ser
3.974SerAla: 3.974 ± 0.955
1.9SerCys: 1.9 ± 0.322
3.801SerAsp: 3.801 ± 0.547
6.047SerGlu: 6.047 ± 0.097
3.801SerPhe: 3.801 ± 0.684
5.874SerGly: 5.874 ± 0.814
2.419SerHis: 2.419 ± 0.682
8.811SerIle: 8.811 ± 1.894
6.565SerLys: 6.565 ± 1.022
9.33SerLeu: 9.33 ± 2.168
0.864SerMet: 0.864 ± 0.19
5.701SerAsn: 5.701 ± 1.177
1.382SerPro: 1.382 ± 1.047
2.246SerGln: 2.246 ± 0.544
4.319SerArg: 4.319 ± 0.188
11.921SerSer: 11.921 ± 1.217
7.084SerThr: 7.084 ± 1.921
7.084SerVal: 7.084 ± 0.927
1.209SerTrp: 1.209 ± 1.317
2.073SerTyr: 2.073 ± 0.592
0.0SerXaa: 0.0 ± 0.0
Thr
2.419ThrAla: 2.419 ± 0.317
1.555ThrCys: 1.555 ± 1.155
2.937ThrAsp: 2.937 ± 0.238
3.628ThrGlu: 3.628 ± 0.092
2.419ThrPhe: 2.419 ± 0.317
3.11ThrGly: 3.11 ± 1.276
1.555ThrHis: 1.555 ± 0.551
5.01ThrIle: 5.01 ± 1.022
3.628ThrLys: 3.628 ± 0.408
5.701ThrLeu: 5.701 ± 0.589
0.864ThrMet: 0.864 ± 0.465
3.283ThrAsn: 3.283 ± 0.296
2.246ThrPro: 2.246 ± 0.306
2.419ThrGln: 2.419 ± 0.848
1.728ThrArg: 1.728 ± 0.231
6.565ThrSer: 6.565 ± 1.417
3.283ThrThr: 3.283 ± 1.68
3.801ThrVal: 3.801 ± 0.26
1.209ThrTrp: 1.209 ± 0.692
1.382ThrTyr: 1.382 ± 0.243
0.0ThrXaa: 0.0 ± 0.0
Val
2.592ValAla: 2.592 ± 0.201
1.728ValCys: 1.728 ± 0.493
3.801ValAsp: 3.801 ± 0.684
4.319ValGlu: 4.319 ± 1.231
2.937ValPhe: 2.937 ± 0.556
3.455ValGly: 3.455 ± 0.506
1.037ValHis: 1.037 ± 0.207
3.801ValIle: 3.801 ± 0.612
5.183ValLys: 5.183 ± 0.377
6.911ValLeu: 6.911 ± 0.628
0.346ValMet: 0.346 ± 0.212
3.283ValAsn: 3.283 ± 0.411
1.728ValPro: 1.728 ± 0.355
3.11ValGln: 3.11 ± 1.647
2.246ValArg: 2.246 ± 0.563
4.838ValSer: 4.838 ± 0.547
3.455ValThr: 3.455 ± 0.459
4.147ValVal: 4.147 ± 1.079
1.209ValTrp: 1.209 ± 0.499
1.728ValTyr: 1.728 ± 0.093
0.0ValXaa: 0.0 ± 0.0
Trp
0.518TrpAla: 0.518 ± 0.385
0.691TrpCys: 0.691 ± 0.617
0.346TrpAsp: 0.346 ± 0.186
1.037TrpGlu: 1.037 ± 0.279
0.518TrpPhe: 0.518 ± 0.452
1.037TrpGly: 1.037 ± 0.552
0.346TrpHis: 0.346 ± 0.212
1.037TrpIle: 1.037 ± 0.273
1.382TrpLys: 1.382 ± 0.345
1.209TrpLeu: 1.209 ± 0.186
0.518TrpMet: 0.518 ± 0.558
0.346TrpAsn: 0.346 ± 0.186
0.864TrpPro: 0.864 ± 0.538
0.173TrpGln: 0.173 ± 0.233
0.691TrpArg: 0.691 ± 0.502
1.209TrpSer: 1.209 ± 0.186
0.691TrpThr: 0.691 ± 0.309
0.518TrpVal: 0.518 ± 0.104
0.173TrpTrp: 0.173 ± 0.093
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.209TyrAla: 1.209 ± 0.186
1.382TyrCys: 1.382 ± 0.345
1.209TyrAsp: 1.209 ± 0.206
1.037TyrGlu: 1.037 ± 0.388
1.555TyrPhe: 1.555 ± 0.311
2.073TyrGly: 2.073 ± 0.581
0.346TyrHis: 0.346 ± 0.155
2.073TyrIle: 2.073 ± 0.365
1.728TyrLys: 1.728 ± 0.38
3.455TyrLeu: 3.455 ± 0.459
0.346TyrMet: 0.346 ± 0.17
1.9TyrAsn: 1.9 ± 0.322
0.691TyrPro: 0.691 ± 0.122
1.037TyrGln: 1.037 ± 0.425
1.037TyrArg: 1.037 ± 0.558
2.937TyrSer: 2.937 ± 0.34
2.246TyrThr: 2.246 ± 0.255
1.382TyrVal: 1.382 ± 0.452
0.518TyrTrp: 0.518 ± 0.213
0.864TyrTyr: 0.864 ± 0.127
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (5789 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski