Amino acid dipepetide frequency for Puccinia striiformis f. sp. tritici PST-78

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.608AlaAla: 5.608 ± 0.042	1.007AlaCys: 1.007 ± 0.013	3.315AlaAsp: 3.315 ± 0.021	3.909AlaGlu: 3.909 ± 0.031	2.371AlaPhe: 2.371 ± 0.02	4.133AlaGly: 4.133 ± 0.034	1.811AlaHis: 1.811 ± 0.016	3.922AlaIle: 3.922 ± 0.028	3.732AlaLys: 3.732 ± 0.026	6.262AlaLeu: 6.262 ± 0.036	1.437AlaMet: 1.437 ± 0.013	2.897AlaAsn: 2.897 ± 0.02	3.971AlaPro: 3.971 ± 0.034	3.076AlaGln: 3.076 ± 0.021	3.873AlaArg: 3.873 ± 0.025	6.281AlaSer: 6.281 ± 0.035	4.367AlaThr: 4.367 ± 0.024	3.507AlaVal: 3.507 ± 0.026	0.848AlaTrp: 0.848 ± 0.011	1.599AlaTyr: 1.599 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	0.808CysAla: 0.808 ± 0.011	0.302CysCys: 0.302 ± 0.007	0.688CysAsp: 0.688 ± 0.011	0.614CysGlu: 0.614 ± 0.009	0.579CysPhe: 0.579 ± 0.009	0.94CysGly: 0.94 ± 0.013	0.43CysHis: 0.43 ± 0.008	0.654CysIle: 0.654 ± 0.01	0.742CysLys: 0.742 ± 0.01	1.4CysLeu: 1.4 ± 0.017	0.261CysMet: 0.261 ± 0.006	0.509CysAsn: 0.509 ± 0.01	0.841CysPro: 0.841 ± 0.012	0.666CysGln: 0.666 ± 0.009	0.781CysArg: 0.781 ± 0.009	1.231CysSer: 1.231 ± 0.014	0.718CysThr: 0.718 ± 0.011	0.668CysVal: 0.668 ± 0.01	0.208CysTrp: 0.208 ± 0.006	0.387CysTyr: 0.387 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.088AspAla: 3.088 ± 0.023	0.771AspCys: 0.771 ± 0.011	4.099AspAsp: 4.099 ± 0.037	4.015AspGlu: 4.015 ± 0.033	2.088AspPhe: 2.088 ± 0.018	3.306AspGly: 3.306 ± 0.025	1.908AspHis: 1.908 ± 0.018	2.697AspIle: 2.697 ± 0.017	2.577AspLys: 2.577 ± 0.021	5.563AspLeu: 5.563 ± 0.031	0.997AspMet: 0.997 ± 0.01	2.252AspAsn: 2.252 ± 0.017	3.713AspPro: 3.713 ± 0.024	2.992AspGln: 2.992 ± 0.021	2.935AspArg: 2.935 ± 0.025	4.767AspSer: 4.767 ± 0.028	2.65AspThr: 2.65 ± 0.024	2.793AspVal: 2.793 ± 0.022	0.842AspTrp: 0.842 ± 0.011	1.462AspTyr: 1.462 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.215GluAla: 4.215 ± 0.03	0.607GluCys: 0.607 ± 0.01	4.081GluAsp: 4.081 ± 0.031	5.625GluGlu: 5.625 ± 0.05	2.035GluPhe: 2.035 ± 0.018	3.038GluGly: 3.038 ± 0.022	1.363GluHis: 1.363 ± 0.013	3.412GluIle: 3.412 ± 0.023	3.484GluLys: 3.484 ± 0.03	5.634GluLeu: 5.634 ± 0.032	1.253GluMet: 1.253 ± 0.014	2.544GluAsn: 2.544 ± 0.019	2.79GluPro: 2.79 ± 0.025	2.436GluGln: 2.436 ± 0.02	3.206GluArg: 3.206 ± 0.025	4.657GluSer: 4.657 ± 0.029	3.019GluThr: 3.019 ± 0.022	3.085GluVal: 3.085 ± 0.024	0.75GluTrp: 0.75 ± 0.01	1.403GluTyr: 1.403 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	2.115PheAla: 2.115 ± 0.018	0.589PheCys: 0.589 ± 0.01	2.239PheAsp: 2.239 ± 0.017	2.131PheGlu: 2.131 ± 0.018	1.522PhePhe: 1.522 ± 0.017	2.439PheGly: 2.439 ± 0.022	1.018PheHis: 1.018 ± 0.011	2.002PheIle: 2.002 ± 0.02	2.134PheLys: 2.134 ± 0.015	3.418PheLeu: 3.418 ± 0.026	0.694PheMet: 0.694 ± 0.01	1.8PheAsn: 1.8 ± 0.017	1.866PhePro: 1.866 ± 0.016	1.571PheGln: 1.571 ± 0.015	1.845PheArg: 1.845 ± 0.017	3.078PheSer: 3.078 ± 0.024	2.034PheThr: 2.034 ± 0.018	1.968PheVal: 1.968 ± 0.019	0.502PheTrp: 0.502 ± 0.008	1.0PheTyr: 1.0 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	3.555GlyAla: 3.555 ± 0.029	0.851GlyCys: 0.851 ± 0.011	2.788GlyAsp: 2.788 ± 0.021	2.83GlyGlu: 2.83 ± 0.02	2.418GlyPhe: 2.418 ± 0.02	4.553GlyGly: 4.553 ± 0.059	1.53GlyHis: 1.53 ± 0.016	3.173GlyIle: 3.173 ± 0.024	3.258GlyLys: 3.258 ± 0.025	5.439GlyLeu: 5.439 ± 0.034	1.212GlyMet: 1.212 ± 0.016	2.495GlyAsn: 2.495 ± 0.023	2.98GlyPro: 2.98 ± 0.028	2.361GlyGln: 2.361 ± 0.023	3.194GlyArg: 3.194 ± 0.025	5.384GlySer: 5.384 ± 0.035	3.45GlyThr: 3.45 ± 0.023	2.997GlyVal: 2.997 ± 0.023	0.82GlyTrp: 0.82 ± 0.011	1.59GlyTyr: 1.59 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.544HisAla: 1.544 ± 0.014	0.41HisCys: 0.41 ± 0.008	1.361HisAsp: 1.361 ± 0.015	1.378HisGlu: 1.378 ± 0.014	1.033HisPhe: 1.033 ± 0.014	1.43HisGly: 1.43 ± 0.014	1.742HisHis: 1.742 ± 0.027	1.311HisIle: 1.311 ± 0.015	1.285HisLys: 1.285 ± 0.013	2.943HisLeu: 2.943 ± 0.021	0.49HisMet: 0.49 ± 0.008	1.253HisAsn: 1.253 ± 0.014	2.253HisPro: 2.253 ± 0.023	1.983HisGln: 1.983 ± 0.02	1.707HisArg: 1.707 ± 0.018	2.713HisSer: 2.713 ± 0.023	1.488HisThr: 1.488 ± 0.015	1.326HisVal: 1.326 ± 0.013	0.347HisTrp: 0.347 ± 0.007	0.726HisTyr: 0.726 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.439IleAla: 3.439 ± 0.023	0.89IleCys: 0.89 ± 0.013	3.522IleAsp: 3.522 ± 0.025	3.418IleGlu: 3.418 ± 0.024	1.991IlePhe: 1.991 ± 0.02	3.101IleGly: 3.101 ± 0.025	1.557IleHis: 1.557 ± 0.015	2.969IleIle: 2.969 ± 0.021	3.338IleLys: 3.338 ± 0.024	5.105IleLeu: 5.105 ± 0.027	0.976IleMet: 0.976 ± 0.012	2.806IleAsn: 2.806 ± 0.021	3.453IlePro: 3.453 ± 0.021	2.548IleGln: 2.548 ± 0.019	2.981IleArg: 2.981 ± 0.021	4.841IleSer: 4.841 ± 0.03	3.157IleThr: 3.157 ± 0.021	2.879IleVal: 2.879 ± 0.022	0.682IleTrp: 0.682 ± 0.011	1.36IleTyr: 1.36 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.075LysAla: 4.075 ± 0.031	0.645LysCys: 0.645 ± 0.01	2.901LysAsp: 2.901 ± 0.023	3.527LysGlu: 3.527 ± 0.027	2.038LysPhe: 2.038 ± 0.019	2.713LysGly: 2.713 ± 0.022	1.335LysHis: 1.335 ± 0.015	3.334LysIle: 3.334 ± 0.023	4.612LysLys: 4.612 ± 0.046	5.579LysLeu: 5.579 ± 0.03	1.191LysMet: 1.191 ± 0.013	2.608LysAsn: 2.608 ± 0.021	3.368LysPro: 3.368 ± 0.028	2.357LysGln: 2.357 ± 0.019	3.499LysArg: 3.499 ± 0.026	4.814LysSer: 4.814 ± 0.03	3.524LysThr: 3.524 ± 0.025	2.772LysVal: 2.772 ± 0.02	0.693LysTrp: 0.693 ± 0.01	1.396LysTyr: 1.396 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.162LeuAla: 7.162 ± 0.04	1.209LeuCys: 1.209 ± 0.011	5.609LeuAsp: 5.609 ± 0.027	5.68LeuGlu: 5.68 ± 0.037	3.215LeuPhe: 3.215 ± 0.025	5.252LeuGly: 5.252 ± 0.032	2.368LeuHis: 2.368 ± 0.021	5.356LeuIle: 5.356 ± 0.033	5.731LeuLys: 5.731 ± 0.033	8.497LeuLeu: 8.497 ± 0.048	1.843LeuMet: 1.843 ± 0.015	4.437LeuAsn: 4.437 ± 0.026	5.857LeuPro: 5.857 ± 0.037	3.957LeuGln: 3.957 ± 0.025	5.043LeuArg: 5.043 ± 0.031	8.538LeuSer: 8.538 ± 0.045	5.408LeuThr: 5.408 ± 0.026	5.246LeuVal: 5.246 ± 0.032	1.011LeuTrp: 1.011 ± 0.013	2.108LeuTyr: 2.108 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	1.74MetAla: 1.74 ± 0.016	0.255MetCys: 0.255 ± 0.006	1.17MetAsp: 1.17 ± 0.014	1.165MetGlu: 1.165 ± 0.014	0.699MetPhe: 0.699 ± 0.01	1.13MetGly: 1.13 ± 0.016	0.368MetHis: 0.368 ± 0.006	1.302MetIle: 1.302 ± 0.015	1.191MetLys: 1.191 ± 0.013	1.564MetLeu: 1.564 ± 0.015	0.571MetMet: 0.571 ± 0.01	1.02MetAsn: 1.02 ± 0.011	0.943MetPro: 0.943 ± 0.012	0.657MetGln: 0.657 ± 0.009	0.984MetArg: 0.984 ± 0.012	1.797MetSer: 1.797 ± 0.017	1.189MetThr: 1.189 ± 0.013	1.194MetVal: 1.194 ± 0.013	0.253MetTrp: 0.253 ± 0.006	0.449MetTyr: 0.449 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.463AsnAla: 2.463 ± 0.021	0.614AsnCys: 0.614 ± 0.01	2.319AsnAsp: 2.319 ± 0.02	2.444AsnGlu: 2.444 ± 0.017	1.678AsnPhe: 1.678 ± 0.014	2.725AsnGly: 2.725 ± 0.022	1.757AsnHis: 1.757 ± 0.018	2.138AsnIle: 2.138 ± 0.019	2.421AsnLys: 2.421 ± 0.019	4.69AsnLeu: 4.69 ± 0.027	0.797AsnMet: 0.797 ± 0.011	2.884AsnAsn: 2.884 ± 0.034	3.534AsnPro: 3.534 ± 0.027	2.891AsnGln: 2.891 ± 0.024	2.583AsnArg: 2.583 ± 0.02	4.527AsnSer: 4.527 ± 0.032	2.654AsnThr: 2.654 ± 0.019	2.119AsnVal: 2.119 ± 0.017	0.577AsnTrp: 0.577 ± 0.009	1.173AsnTyr: 1.173 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.689ProAla: 4.689 ± 0.036	0.61ProCys: 0.61 ± 0.012	3.124ProAsp: 3.124 ± 0.022	3.375ProGlu: 3.375 ± 0.028	2.018ProPhe: 2.018 ± 0.018	3.339ProGly: 3.339 ± 0.03	1.657ProHis: 1.657 ± 0.018	3.484ProIle: 3.484 ± 0.024	3.194ProLys: 3.194 ± 0.025	5.026ProLeu: 5.026 ± 0.032	1.05ProMet: 1.05 ± 0.014	3.053ProAsn: 3.053 ± 0.023	5.615ProPro: 5.615 ± 0.053	2.585ProGln: 2.585 ± 0.026	2.994ProArg: 2.994 ± 0.025	7.428ProSer: 7.428 ± 0.048	4.961ProThr: 4.961 ± 0.031	3.344ProVal: 3.344 ± 0.029	0.562ProTrp: 0.562 ± 0.01	1.192ProTyr: 1.192 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.571GlnAla: 3.571 ± 0.025	0.49GlnCys: 0.49 ± 0.008	2.362GlnAsp: 2.362 ± 0.02	2.717GlnGlu: 2.717 ± 0.021	1.523GlnPhe: 1.523 ± 0.014	2.04GlnGly: 2.04 ± 0.019	1.416GlnHis: 1.416 ± 0.017	2.608GlnIle: 2.608 ± 0.019	2.439GlnLys: 2.439 ± 0.02	4.523GlnLeu: 4.523 ± 0.028	0.931GlnMet: 0.931 ± 0.012	2.04GlnAsn: 2.04 ± 0.02	3.129GlnPro: 3.129 ± 0.027	3.28GlnGln: 3.28 ± 0.065	2.451GlnArg: 2.451 ± 0.02	4.414GlnSer: 4.414 ± 0.027	2.809GlnThr: 2.809 ± 0.02	2.427GlnVal: 2.427 ± 0.021	0.512GlnTrp: 0.512 ± 0.009	0.988GlnTyr: 0.988 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	3.76ArgAla: 3.76 ± 0.023	0.776ArgCys: 0.776 ± 0.012	2.644ArgAsp: 2.644 ± 0.02	2.903ArgGlu: 2.903 ± 0.024	2.075ArgPhe: 2.075 ± 0.016	2.791ArgGly: 2.791 ± 0.023	1.458ArgHis: 1.458 ± 0.015	3.036ArgIle: 3.036 ± 0.023	3.472ArgLys: 3.472 ± 0.025	5.575ArgLeu: 5.575 ± 0.032	1.188ArgMet: 1.188 ± 0.013	2.366ArgAsn: 2.366 ± 0.02	3.408ArgPro: 3.408 ± 0.027	2.483ArgGln: 2.483 ± 0.019	4.019ArgArg: 4.019 ± 0.026	5.095ArgSer: 5.095 ± 0.031	3.25ArgThr: 3.25 ± 0.024	2.747ArgVal: 2.747 ± 0.019	0.755ArgTrp: 0.755 ± 0.01	1.404ArgTyr: 1.404 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.109SerAla: 6.109 ± 0.033	1.172SerCys: 1.172 ± 0.015	4.997SerAsp: 4.997 ± 0.033	4.57SerGlu: 4.57 ± 0.029	3.293SerPhe: 3.293 ± 0.021	5.158SerGly: 5.158 ± 0.036	2.738SerHis: 2.738 ± 0.022	5.208SerIle: 5.208 ± 0.031	5.099SerLys: 5.099 ± 0.031	8.233SerLeu: 8.233 ± 0.04	1.774SerMet: 1.774 ± 0.017	4.823SerAsn: 4.823 ± 0.032	6.122SerPro: 6.122 ± 0.042	4.224SerGln: 4.224 ± 0.026	5.07SerArg: 5.07 ± 0.027	12.616SerSer: 12.616 ± 0.086	7.188SerThr: 7.188 ± 0.038	4.355SerVal: 4.355 ± 0.026	0.959SerTrp: 0.959 ± 0.012	1.995SerTyr: 1.995 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	4.058ThrAla: 4.058 ± 0.026	0.867ThrCys: 0.867 ± 0.012	3.012ThrAsp: 3.012 ± 0.024	3.04ThrGlu: 3.04 ± 0.02	2.031ThrPhe: 2.031 ± 0.016	3.702ThrGly: 3.702 ± 0.027	1.696ThrHis: 1.696 ± 0.015	3.463ThrIle: 3.463 ± 0.024	3.282ThrLys: 3.282 ± 0.024	5.43ThrLeu: 5.43 ± 0.03	1.142ThrMet: 1.142 ± 0.011	3.03ThrAsn: 3.03 ± 0.02	4.444ThrPro: 4.444 ± 0.029	2.674ThrGln: 2.674 ± 0.021	3.367ThrArg: 3.367 ± 0.022	6.44ThrSer: 6.44 ± 0.034	5.203ThrThr: 5.203 ± 0.039	3.029ThrVal: 3.029 ± 0.023	0.759ThrTrp: 0.759 ± 0.01	1.381ThrTyr: 1.381 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	3.71ValAla: 3.71 ± 0.026	0.764ValCys: 0.764 ± 0.011	3.228ValAsp: 3.228 ± 0.02	3.306ValGlu: 3.306 ± 0.025	1.895ValPhe: 1.895 ± 0.016	3.031ValGly: 3.031 ± 0.027	1.39ValHis: 1.39 ± 0.013	2.968ValIle: 2.968 ± 0.022	2.921ValLys: 2.921 ± 0.022	4.788ValLeu: 4.788 ± 0.027	1.057ValMet: 1.057 ± 0.012	2.339ValAsn: 2.339 ± 0.018	3.061ValPro: 3.061 ± 0.024	2.191ValGln: 2.191 ± 0.019	2.598ValArg: 2.598 ± 0.017	4.057ValSer: 4.057 ± 0.027	2.976ValThr: 2.976 ± 0.019	3.196ValVal: 3.196 ± 0.023	0.691ValTrp: 0.691 ± 0.01	1.326ValTyr: 1.326 ± 0.013	0.0ValXaa: 0.0 ± 0.0
Trp	0.829TrpAla: 0.829 ± 0.011	0.21TrpCys: 0.21 ± 0.006	0.704TrpAsp: 0.704 ± 0.012	0.727TrpGlu: 0.727 ± 0.011	0.451TrpPhe: 0.451 ± 0.008	0.626TrpGly: 0.626 ± 0.01	0.3TrpHis: 0.3 ± 0.007	0.771TrpIle: 0.771 ± 0.011	0.871TrpLys: 0.871 ± 0.011	1.237TrpLeu: 1.237 ± 0.014	0.296TrpMet: 0.296 ± 0.006	0.7TrpAsn: 0.7 ± 0.009	0.511TrpPro: 0.511 ± 0.009	0.499TrpGln: 0.499 ± 0.009	0.683TrpArg: 0.683 ± 0.01	1.012TrpSer: 1.012 ± 0.012	0.741TrpThr: 0.741 ± 0.012	0.623TrpVal: 0.623 ± 0.009	0.208TrpTrp: 0.208 ± 0.006	0.315TrpTyr: 0.315 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.388TyrAla: 1.388 ± 0.016	0.385TyrCys: 0.385 ± 0.009	1.352TyrAsp: 1.352 ± 0.015	1.266TyrGlu: 1.266 ± 0.014	1.013TyrPhe: 1.013 ± 0.01	1.431TyrGly: 1.431 ± 0.016	0.879TyrHis: 0.879 ± 0.011	1.206TyrIle: 1.206 ± 0.015	1.2TyrLys: 1.2 ± 0.013	2.62TyrLeu: 2.62 ± 0.019	0.479TyrMet: 0.479 ± 0.009	1.135TyrAsn: 1.135 ± 0.013	1.442TyrPro: 1.442 ± 0.015	1.236TyrGln: 1.236 ± 0.016	1.391TyrArg: 1.391 ± 0.015	2.015TyrSer: 2.015 ± 0.017	1.265TyrThr: 1.265 ± 0.014	1.217TyrVal: 1.217 ± 0.013	0.335TyrTrp: 0.335 ± 0.008	0.789TyrTyr: 0.789 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 19932 proteins (7397404 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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