Amino acid dipepetide frequency for Hubei permutotetra-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.424AlaAla: 10.424 ± 1.226
0.695AlaCys: 0.695 ± 0.315
5.559AlaAsp: 5.559 ± 5.415
4.864AlaGlu: 4.864 ± 2.205
0.695AlaPhe: 0.695 ± 0.315
4.864AlaGly: 4.864 ± 0.221
1.39AlaHis: 1.39 ± 0.63
5.559AlaIle: 5.559 ± 0.536
6.949AlaLys: 6.949 ± 2.801
6.254AlaLeu: 6.254 ± 0.851
2.78AlaMet: 2.78 ± 2.708
4.17AlaAsn: 4.17 ± 1.89
8.339AlaPro: 8.339 ± 1.796
0.0AlaGln: 0.0 ± 0.0
4.17AlaArg: 4.17 ± 1.89
4.864AlaSer: 4.864 ± 0.221
6.949AlaThr: 6.949 ± 2.801
6.254AlaVal: 6.254 ± 1.133
2.085AlaTrp: 2.085 ± 1.039
4.864AlaTyr: 4.864 ± 0.221
0.0AlaXaa: 0.0 ± 0.0
Cys
2.085CysAla: 2.085 ± 0.945
0.695CysCys: 0.695 ± 0.315
0.0CysAsp: 0.0 ± 0.0
1.39CysGlu: 1.39 ± 0.63
0.695CysPhe: 0.695 ± 0.315
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.39CysLeu: 1.39 ± 0.63
0.0CysMet: 0.0 ± 0.0
1.39CysAsn: 1.39 ± 0.63
1.39CysPro: 1.39 ± 0.63
0.695CysGln: 0.695 ± 1.669
0.0CysArg: 0.0 ± 0.0
0.695CysSer: 0.695 ± 1.669
0.695CysThr: 0.695 ± 0.315
0.695CysVal: 0.695 ± 0.315
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
10.424AspAla: 10.424 ± 1.226
0.0AspCys: 0.0 ± 0.0
3.475AspAsp: 3.475 ± 0.409
4.864AspGlu: 4.864 ± 2.205
2.085AspPhe: 2.085 ± 0.945
6.254AspGly: 6.254 ± 2.835
0.695AspHis: 0.695 ± 0.315
3.475AspIle: 3.475 ± 0.409
0.695AspLys: 0.695 ± 0.315
5.559AspLeu: 5.559 ± 2.52
2.085AspMet: 2.085 ± 0.945
0.695AspAsn: 0.695 ± 0.315
4.864AspPro: 4.864 ± 2.205
0.695AspGln: 0.695 ± 0.315
3.475AspArg: 3.475 ± 0.409
2.78AspSer: 2.78 ± 0.724
2.78AspThr: 2.78 ± 1.26
5.559AspVal: 5.559 ± 1.448
2.085AspTrp: 2.085 ± 1.039
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.78GluAla: 2.78 ± 1.26
1.39GluCys: 1.39 ± 0.63
2.78GluAsp: 2.78 ± 1.26
0.695GluGlu: 0.695 ± 0.315
4.17GluPhe: 4.17 ± 1.89
2.78GluGly: 2.78 ± 0.724
1.39GluHis: 1.39 ± 0.63
4.864GluIle: 4.864 ± 2.205
1.39GluLys: 1.39 ± 0.63
4.864GluLeu: 4.864 ± 0.221
2.085GluMet: 2.085 ± 2.89
2.085GluAsn: 2.085 ± 0.945
1.39GluPro: 1.39 ± 0.63
0.695GluGln: 0.695 ± 0.315
7.644GluArg: 7.644 ± 0.503
0.695GluSer: 0.695 ± 0.315
2.78GluThr: 2.78 ± 1.26
2.78GluVal: 2.78 ± 1.26
0.695GluTrp: 0.695 ± 0.315
0.695GluTyr: 0.695 ± 0.315
0.0GluXaa: 0.0 ± 0.0
Phe
0.695PheAla: 0.695 ± 0.315
0.695PheCys: 0.695 ± 0.315
1.39PheAsp: 1.39 ± 0.63
2.085PheGlu: 2.085 ± 1.039
1.39PhePhe: 1.39 ± 0.63
1.39PheGly: 1.39 ± 1.354
0.0PheHis: 0.0 ± 0.0
1.39PheIle: 1.39 ± 0.63
2.085PheLys: 2.085 ± 0.945
1.39PheLeu: 1.39 ± 0.63
1.39PheMet: 1.39 ± 0.63
0.695PheAsn: 0.695 ± 0.315
2.78PhePro: 2.78 ± 1.26
1.39PheGln: 1.39 ± 0.63
2.085PheArg: 2.085 ± 0.945
5.559PheSer: 5.559 ± 0.536
1.39PheThr: 1.39 ± 0.63
0.0PheVal: 0.0 ± 0.0
0.695PheTrp: 0.695 ± 0.315
2.085PheTyr: 2.085 ± 3.023
0.0PheXaa: 0.0 ± 0.0
Gly
4.17GlyAla: 4.17 ± 0.094
0.0GlyCys: 0.0 ± 0.0
3.475GlyAsp: 3.475 ± 1.575
1.39GlyGlu: 1.39 ± 1.354
2.085GlyPhe: 2.085 ± 0.945
4.864GlyGly: 4.864 ± 1.763
0.695GlyHis: 0.695 ± 0.315
4.17GlyIle: 4.17 ± 6.045
2.085GlyLys: 2.085 ± 0.945
7.644GlyLeu: 7.644 ± 1.481
1.39GlyMet: 1.39 ± 0.63
0.695GlyAsn: 0.695 ± 1.669
6.254GlyPro: 6.254 ± 0.851
1.39GlyGln: 1.39 ± 0.63
3.475GlyArg: 3.475 ± 1.575
6.254GlySer: 6.254 ± 0.851
6.254GlyThr: 6.254 ± 3.116
4.17GlyVal: 4.17 ± 0.094
0.0GlyTrp: 0.0 ± 0.0
2.085GlyTyr: 2.085 ± 0.945
0.0GlyXaa: 0.0 ± 0.0
His
1.39HisAla: 1.39 ± 1.354
1.39HisCys: 1.39 ± 0.63
0.695HisAsp: 0.695 ± 0.315
0.695HisGlu: 0.695 ± 1.669
0.695HisPhe: 0.695 ± 0.315
2.085HisGly: 2.085 ± 0.945
0.0HisHis: 0.0 ± 0.0
0.695HisIle: 0.695 ± 0.315
0.695HisLys: 0.695 ± 0.315
5.559HisLeu: 5.559 ± 0.536
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.085HisPro: 2.085 ± 0.945
1.39HisGln: 1.39 ± 0.63
2.085HisArg: 2.085 ± 0.945
1.39HisSer: 1.39 ± 1.354
0.695HisThr: 0.695 ± 0.315
0.695HisVal: 0.695 ± 0.315
0.695HisTrp: 0.695 ± 0.315
1.39HisTyr: 1.39 ± 0.63
0.0HisXaa: 0.0 ± 0.0
Ile
5.559IleAla: 5.559 ± 3.431
0.695IleCys: 0.695 ± 0.315
4.864IleAsp: 4.864 ± 1.763
2.085IleGlu: 2.085 ± 0.945
2.085IlePhe: 2.085 ± 1.039
0.695IleGly: 0.695 ± 0.315
2.085IleHis: 2.085 ± 0.945
2.085IleIle: 2.085 ± 0.945
4.17IleLys: 4.17 ± 1.89
6.254IleLeu: 6.254 ± 2.835
1.39IleMet: 1.39 ± 0.63
2.78IleAsn: 2.78 ± 0.724
4.17IlePro: 4.17 ± 0.094
1.39IleGln: 1.39 ± 3.338
3.475IleArg: 3.475 ± 1.575
4.17IleSer: 4.17 ± 0.094
1.39IleThr: 1.39 ± 1.354
2.78IleVal: 2.78 ± 0.724
0.695IleTrp: 0.695 ± 0.315
0.695IleTyr: 0.695 ± 0.315
0.0IleXaa: 0.0 ± 0.0
Lys
2.085LysAla: 2.085 ± 0.945
0.695LysCys: 0.695 ± 0.315
1.39LysAsp: 1.39 ± 0.63
3.475LysGlu: 3.475 ± 1.575
2.085LysPhe: 2.085 ± 0.945
1.39LysGly: 1.39 ± 1.354
2.085LysHis: 2.085 ± 0.945
2.085LysIle: 2.085 ± 0.945
2.78LysLys: 2.78 ± 2.708
2.78LysLeu: 2.78 ± 0.724
1.39LysMet: 1.39 ± 1.354
5.559LysAsn: 5.559 ± 0.536
6.254LysPro: 6.254 ± 1.133
2.78LysGln: 2.78 ± 1.26
5.559LysArg: 5.559 ± 1.448
4.17LysSer: 4.17 ± 0.094
4.17LysThr: 4.17 ± 0.094
1.39LysVal: 1.39 ± 3.338
0.0LysTrp: 0.0 ± 0.0
2.085LysTyr: 2.085 ± 0.945
0.0LysXaa: 0.0 ± 0.0
Leu
8.339LeuAla: 8.339 ± 1.796
2.085LeuCys: 2.085 ± 0.945
5.559LeuAsp: 5.559 ± 2.52
5.559LeuGlu: 5.559 ± 2.52
2.085LeuPhe: 2.085 ± 0.945
4.864LeuGly: 4.864 ± 2.205
1.39LeuHis: 1.39 ± 0.63
4.864LeuIle: 4.864 ± 0.221
3.475LeuLys: 3.475 ± 2.393
4.864LeuLeu: 4.864 ± 1.763
3.475LeuMet: 3.475 ± 1.575
2.085LeuAsn: 2.085 ± 0.945
6.949LeuPro: 6.949 ± 3.15
3.475LeuGln: 3.475 ± 0.409
4.864LeuArg: 4.864 ± 0.221
6.254LeuSer: 6.254 ± 2.835
7.644LeuThr: 7.644 ± 6.454
2.78LeuVal: 2.78 ± 0.724
2.085LeuTrp: 2.085 ± 1.039
5.559LeuTyr: 5.559 ± 2.52
0.0LeuXaa: 0.0 ± 0.0
Met
2.78MetAla: 2.78 ± 0.724
0.695MetCys: 0.695 ± 0.315
3.475MetAsp: 3.475 ± 0.409
3.475MetGlu: 3.475 ± 0.409
0.695MetPhe: 0.695 ± 0.315
0.0MetGly: 0.0 ± 0.0
0.695MetHis: 0.695 ± 0.315
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.78MetLeu: 2.78 ± 0.724
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.695MetPro: 0.695 ± 0.315
0.695MetGln: 0.695 ± 1.669
0.695MetArg: 0.695 ± 0.315
1.39MetSer: 1.39 ± 1.354
2.78MetThr: 2.78 ± 0.724
2.085MetVal: 2.085 ± 1.039
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.085AsnAla: 2.085 ± 0.945
0.0AsnCys: 0.0 ± 0.0
1.39AsnAsp: 1.39 ± 0.63
1.39AsnGlu: 1.39 ± 0.63
1.39AsnPhe: 1.39 ± 0.63
4.17AsnGly: 4.17 ± 0.094
0.0AsnHis: 0.0 ± 0.0
3.475AsnIle: 3.475 ± 0.409
2.085AsnLys: 2.085 ± 0.945
2.085AsnLeu: 2.085 ± 0.945
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
6.254AsnPro: 6.254 ± 2.835
1.39AsnGln: 1.39 ± 0.63
1.39AsnArg: 1.39 ± 0.63
3.475AsnSer: 3.475 ± 0.409
4.864AsnThr: 4.864 ± 2.205
2.085AsnVal: 2.085 ± 0.945
0.695AsnTrp: 0.695 ± 0.315
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
7.644ProAla: 7.644 ± 2.486
0.0ProCys: 0.0 ± 0.0
10.424ProAsp: 10.424 ± 4.725
2.78ProGlu: 2.78 ± 1.26
0.695ProPhe: 0.695 ± 0.315
4.17ProGly: 4.17 ± 0.094
1.39ProHis: 1.39 ± 0.63
6.949ProIle: 6.949 ± 3.15
4.17ProLys: 4.17 ± 0.094
6.254ProLeu: 6.254 ± 0.851
2.085ProMet: 2.085 ± 0.312
4.864ProAsn: 4.864 ± 2.205
9.034ProPro: 9.034 ± 4.095
2.78ProGln: 2.78 ± 1.26
8.339ProArg: 8.339 ± 1.796
2.78ProSer: 2.78 ± 2.708
6.254ProThr: 6.254 ± 2.835
1.39ProVal: 1.39 ± 1.354
0.695ProTrp: 0.695 ± 0.315
2.085ProTyr: 2.085 ± 0.945
0.0ProXaa: 0.0 ± 0.0
Gln
3.475GlnAla: 3.475 ± 0.409
0.0GlnCys: 0.0 ± 0.0
0.695GlnAsp: 0.695 ± 0.315
2.085GlnGlu: 2.085 ± 0.945
1.39GlnPhe: 1.39 ± 0.63
1.39GlnGly: 1.39 ± 0.63
0.695GlnHis: 0.695 ± 0.315
1.39GlnIle: 1.39 ± 0.63
2.085GlnLys: 2.085 ± 0.945
2.78GlnLeu: 2.78 ± 1.26
0.695GlnMet: 0.695 ± 0.315
0.0GlnAsn: 0.0 ± 0.0
3.475GlnPro: 3.475 ± 0.409
0.0GlnGln: 0.0 ± 0.0
2.085GlnArg: 2.085 ± 1.039
2.085GlnSer: 2.085 ± 1.039
0.695GlnThr: 0.695 ± 0.315
2.085GlnVal: 2.085 ± 0.945
0.0GlnTrp: 0.0 ± 0.0
0.695GlnTyr: 0.695 ± 1.669
0.0GlnXaa: 0.0 ± 0.0
Arg
4.864ArgAla: 4.864 ± 1.763
0.0ArgCys: 0.0 ± 0.0
4.17ArgAsp: 4.17 ± 1.89
4.864ArgGlu: 4.864 ± 2.205
1.39ArgPhe: 1.39 ± 1.354
4.864ArgGly: 4.864 ± 2.205
2.085ArgHis: 2.085 ± 1.039
2.085ArgIle: 2.085 ± 0.945
5.559ArgLys: 5.559 ± 2.52
6.254ArgLeu: 6.254 ± 0.851
0.695ArgMet: 0.695 ± 0.315
1.39ArgAsn: 1.39 ± 0.63
6.949ArgPro: 6.949 ± 1.166
3.475ArgGln: 3.475 ± 1.575
13.204ArgArg: 13.204 ± 11.869
2.78ArgSer: 2.78 ± 2.708
3.475ArgThr: 3.475 ± 4.376
4.17ArgVal: 4.17 ± 0.094
1.39ArgTrp: 1.39 ± 0.63
2.085ArgTyr: 2.085 ± 0.945
0.0ArgXaa: 0.0 ± 0.0
Ser
6.949SerAla: 6.949 ± 2.801
0.0SerCys: 0.0 ± 0.0
2.78SerAsp: 2.78 ± 1.26
2.78SerGlu: 2.78 ± 0.724
3.475SerPhe: 3.475 ± 2.393
5.559SerGly: 5.559 ± 3.431
2.085SerHis: 2.085 ± 0.945
2.78SerIle: 2.78 ± 0.724
6.254SerLys: 6.254 ± 1.133
10.424SerLeu: 10.424 ± 3.21
0.695SerMet: 0.695 ± 0.315
4.17SerAsn: 4.17 ± 1.89
1.39SerPro: 1.39 ± 0.63
2.085SerGln: 2.085 ± 0.945
2.78SerArg: 2.78 ± 0.724
4.864SerSer: 4.864 ± 3.746
4.17SerThr: 4.17 ± 2.078
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
0.695SerTyr: 0.695 ± 0.315
0.0SerXaa: 0.0 ± 0.0
Thr
6.949ThrAla: 6.949 ± 1.166
0.0ThrCys: 0.0 ± 0.0
3.475ThrAsp: 3.475 ± 0.409
0.0ThrGlu: 0.0 ± 0.0
2.78ThrPhe: 2.78 ± 0.724
6.254ThrGly: 6.254 ± 1.133
3.475ThrHis: 3.475 ± 2.393
3.475ThrIle: 3.475 ± 4.376
4.864ThrLys: 4.864 ± 1.763
4.864ThrLeu: 4.864 ± 2.205
0.695ThrMet: 0.695 ± 0.315
3.475ThrAsn: 3.475 ± 1.575
4.17ThrPro: 4.17 ± 2.078
2.78ThrGln: 2.78 ± 1.26
5.559ThrArg: 5.559 ± 1.448
2.78ThrSer: 2.78 ± 0.724
4.864ThrThr: 4.864 ± 0.221
6.254ThrVal: 6.254 ± 5.1
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.864ValAla: 4.864 ± 0.221
1.39ValCys: 1.39 ± 1.354
1.39ValAsp: 1.39 ± 0.63
2.78ValGlu: 2.78 ± 0.724
0.695ValPhe: 0.695 ± 0.315
3.475ValGly: 3.475 ± 2.393
2.085ValHis: 2.085 ± 0.945
1.39ValIle: 1.39 ± 0.63
2.085ValLys: 2.085 ± 1.039
1.39ValLeu: 1.39 ± 1.354
0.695ValMet: 0.695 ± 1.669
2.78ValAsn: 2.78 ± 1.26
6.254ValPro: 6.254 ± 1.133
0.695ValGln: 0.695 ± 0.315
3.475ValArg: 3.475 ± 0.409
5.559ValSer: 5.559 ± 1.448
3.475ValThr: 3.475 ± 2.393
4.864ValVal: 4.864 ± 5.73
0.695ValTrp: 0.695 ± 1.669
1.39ValTyr: 1.39 ± 0.63
0.0ValXaa: 0.0 ± 0.0
Trp
1.39TrpAla: 1.39 ± 0.63
0.695TrpCys: 0.695 ± 1.669
2.085TrpAsp: 2.085 ± 0.945
1.39TrpGlu: 1.39 ± 0.63
0.0TrpPhe: 0.0 ± 0.0
0.695TrpGly: 0.695 ± 0.315
1.39TrpHis: 1.39 ± 1.354
1.39TrpIle: 1.39 ± 0.63
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.695TrpMet: 0.695 ± 1.669
0.0TrpAsn: 0.0 ± 0.0
0.695TrpPro: 0.695 ± 0.315
0.0TrpGln: 0.0 ± 0.0
1.39TrpArg: 1.39 ± 0.63
0.695TrpSer: 0.695 ± 1.669
0.0TrpThr: 0.0 ± 0.0
0.695TrpVal: 0.695 ± 0.315
0.695TrpTrp: 0.695 ± 0.315
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.78TyrAla: 2.78 ± 1.26
0.695TyrCys: 0.695 ± 0.315
3.475TyrAsp: 3.475 ± 0.409
0.695TyrGlu: 0.695 ± 0.315
0.0TyrPhe: 0.0 ± 0.0
2.78TyrGly: 2.78 ± 0.724
0.695TyrHis: 0.695 ± 0.315
1.39TyrIle: 1.39 ± 1.354
2.78TyrLys: 2.78 ± 0.724
4.864TyrLeu: 4.864 ± 2.205
0.0TyrMet: 0.0 ± 0.0
1.39TyrAsn: 1.39 ± 0.63
1.39TyrPro: 1.39 ± 0.63
0.0TyrGln: 0.0 ± 0.0
0.0TyrArg: 0.0 ± 0.0
0.695TyrSer: 0.695 ± 0.315
1.39TyrThr: 1.39 ± 0.63
0.695TyrVal: 0.695 ± 0.315
0.695TyrTrp: 0.695 ± 0.315
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski