Chikungunya virus (strain S27-African prototype) (CHIKV)

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; Martellivirales; Togaviridae; Alphavirus; Chikungunya virus

Average proteome isoelectric point is 7.58

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|Q8JUX6|POLN_CHIKS Polyprotein P1234 OS=Chikungunya virus (strain S27-African prototype) OX=371094 PE=1 SV=1
MM1 pKa = 7.89DD2 pKa = 5.21PVYY5 pKa = 11.34VDD7 pKa = 4.09IDD9 pKa = 3.79ADD11 pKa = 4.05SAFLKK16 pKa = 10.47ALQRR20 pKa = 11.84AYY22 pKa = 10.25PMFEE26 pKa = 3.74VEE28 pKa = 4.4PRR30 pKa = 11.84QVTPNDD36 pKa = 3.5HH37 pKa = 6.55ANARR41 pKa = 11.84AFSHH45 pKa = 6.71LAIKK49 pKa = 10.58LIEE52 pKa = 4.04QEE54 pKa = 4.2IDD56 pKa = 3.27PDD58 pKa = 4.09STILDD63 pKa = 3.6IGSAPARR70 pKa = 11.84RR71 pKa = 11.84MMSDD75 pKa = 2.96RR76 pKa = 11.84KK77 pKa = 8.34YY78 pKa = 10.79HH79 pKa = 5.8CVCPMRR85 pKa = 11.84SAEE88 pKa = 4.16DD89 pKa = 3.71PEE91 pKa = 4.92RR92 pKa = 11.84LANYY96 pKa = 8.93ARR98 pKa = 11.84KK99 pKa = 8.97LASAAGKK106 pKa = 10.35VLDD109 pKa = 4.51RR110 pKa = 11.84NISGKK115 pKa = 10.18IGDD118 pKa = 4.53LQAVMAVPDD127 pKa = 3.94TEE129 pKa = 4.47TPTFCLHH136 pKa = 6.5TDD138 pKa = 3.69VSCRR142 pKa = 11.84QRR144 pKa = 11.84ADD146 pKa = 3.07VAIYY150 pKa = 8.76QDD152 pKa = 4.04VYY154 pKa = 11.34AVHH157 pKa = 7.13APTSLYY163 pKa = 9.58HH164 pKa = 4.98QAIKK168 pKa = 10.4GVRR171 pKa = 11.84LAYY174 pKa = 9.11WVGFDD179 pKa = 3.95TTPFMYY185 pKa = 10.67NAMAGAYY192 pKa = 8.71PSYY195 pKa = 8.93STNWADD201 pKa = 3.97EE202 pKa = 4.18QVLKK206 pKa = 10.97AKK208 pKa = 10.73NIGLCSTDD216 pKa = 2.98LTEE219 pKa = 4.41GRR221 pKa = 11.84RR222 pKa = 11.84GKK224 pKa = 10.58LSIMRR229 pKa = 11.84GKK231 pKa = 10.39KK232 pKa = 10.06LEE234 pKa = 4.26PCDD237 pKa = 3.37RR238 pKa = 11.84VLFSVGSTLYY248 pKa = 10.18PEE250 pKa = 4.21SRR252 pKa = 11.84KK253 pKa = 9.79LLKK256 pKa = 10.07SWHH259 pKa = 6.32LPSVFHH265 pKa = 6.88LKK267 pKa = 10.6GKK269 pKa = 10.59LSFTCRR275 pKa = 11.84CDD277 pKa = 3.45TVVSCEE283 pKa = 4.13GYY285 pKa = 8.19VVKK288 pKa = 10.51RR289 pKa = 11.84ITMSPGLYY297 pKa = 10.59GKK299 pKa = 6.32TTGYY303 pKa = 11.26AVTHH307 pKa = 6.33HH308 pKa = 7.31ADD310 pKa = 3.19GFLMCKK316 pKa = 7.8TTDD319 pKa = 3.33TVDD322 pKa = 3.34GEE324 pKa = 4.3RR325 pKa = 11.84VSFSVCTYY333 pKa = 10.63VPATICDD340 pKa = 3.51QMTGILATEE349 pKa = 4.18VTPEE353 pKa = 4.07DD354 pKa = 3.69AQKK357 pKa = 11.43LLVGLNQRR365 pKa = 11.84IVVNGRR371 pKa = 11.84TQRR374 pKa = 11.84NTNTMKK380 pKa = 10.76NYY382 pKa = 7.77MIPVVAQAFSKK393 pKa = 8.95WAKK396 pKa = 8.96EE397 pKa = 3.94CRR399 pKa = 11.84KK400 pKa = 10.72DD401 pKa = 3.83MEE403 pKa = 4.56DD404 pKa = 3.38EE405 pKa = 4.04KK406 pKa = 11.46LLGVRR411 pKa = 11.84EE412 pKa = 4.06RR413 pKa = 11.84TLTCCCLWAFKK424 pKa = 10.15KK425 pKa = 10.59QKK427 pKa = 8.09THH429 pKa = 4.73TVYY432 pKa = 10.5KK433 pKa = 10.62RR434 pKa = 11.84PDD436 pKa = 3.28TQSIQKK442 pKa = 9.06VQAEE446 pKa = 4.2FDD448 pKa = 4.05SFVVPSLWSSGLSIPLRR465 pKa = 11.84TRR467 pKa = 11.84IKK469 pKa = 9.31WLLSKK474 pKa = 10.69VPKK477 pKa = 9.86TDD479 pKa = 3.3LTPYY483 pKa = 10.63SGDD486 pKa = 3.4AQEE489 pKa = 5.5ARR491 pKa = 11.84DD492 pKa = 3.82AEE494 pKa = 4.36KK495 pKa = 10.29EE496 pKa = 4.07AEE498 pKa = 4.2EE499 pKa = 3.98EE500 pKa = 4.27RR501 pKa = 11.84EE502 pKa = 4.26AEE504 pKa = 4.23LTLEE508 pKa = 4.55ALPPLQAAQEE518 pKa = 4.13DD519 pKa = 4.51VQVEE523 pKa = 3.94IDD525 pKa = 3.73VEE527 pKa = 4.19QLEE530 pKa = 4.4DD531 pKa = 3.23RR532 pKa = 11.84AGAGIIEE539 pKa = 4.49TPRR542 pKa = 11.84GAIKK546 pKa = 9.54VTAQPTDD553 pKa = 3.63HH554 pKa = 6.9VVGEE558 pKa = 4.17YY559 pKa = 10.68LVLSPQTVLRR569 pKa = 11.84SQKK572 pKa = 10.51LSLIHH577 pKa = 7.08ALAEE581 pKa = 4.08QVKK584 pKa = 7.8TCTHH588 pKa = 6.34SGRR591 pKa = 11.84AGRR594 pKa = 11.84YY595 pKa = 8.62AVEE598 pKa = 4.65AYY600 pKa = 10.0DD601 pKa = 3.95GRR603 pKa = 11.84VLVPSGYY610 pKa = 10.65AISPEE615 pKa = 4.1DD616 pKa = 3.72FQSLSEE622 pKa = 4.33SATMVYY628 pKa = 10.35NEE630 pKa = 4.29RR631 pKa = 11.84EE632 pKa = 3.92FVNRR636 pKa = 11.84KK637 pKa = 7.04LHH639 pKa = 6.46HH640 pKa = 6.54IAMHH644 pKa = 6.35GPALNTDD651 pKa = 3.58EE652 pKa = 4.83EE653 pKa = 5.09SYY655 pKa = 11.13EE656 pKa = 3.91LVRR659 pKa = 11.84AEE661 pKa = 4.2RR662 pKa = 11.84TEE664 pKa = 3.75HH665 pKa = 6.32EE666 pKa = 4.36YY667 pKa = 11.33VYY669 pKa = 11.02DD670 pKa = 3.39VDD672 pKa = 5.23QRR674 pKa = 11.84RR675 pKa = 11.84CCKK678 pKa = 10.22KK679 pKa = 10.1EE680 pKa = 3.61EE681 pKa = 4.02AAGLVLVGDD690 pKa = 4.48LTNPPYY696 pKa = 10.75HH697 pKa = 6.34EE698 pKa = 4.2FAYY701 pKa = 9.94EE702 pKa = 3.93GLKK705 pKa = 9.81IRR707 pKa = 11.84PACPYY712 pKa = 9.0KK713 pKa = 10.29IAVIGVFGVPGSGKK727 pKa = 10.04SAIIKK732 pKa = 10.27NLVTRR737 pKa = 11.84QDD739 pKa = 3.56LVTSGKK745 pKa = 10.11KK746 pKa = 9.68EE747 pKa = 3.72NCQEE751 pKa = 3.48ITTDD755 pKa = 3.14VMRR758 pKa = 11.84QRR760 pKa = 11.84GLEE763 pKa = 3.7ISARR767 pKa = 11.84TVDD770 pKa = 3.85SLLLNGCNRR779 pKa = 11.84PVDD782 pKa = 3.69VLYY785 pKa = 11.01VDD787 pKa = 4.38EE788 pKa = 6.04AFACHH793 pKa = 6.76SGTLLALIALVRR805 pKa = 11.84PRR807 pKa = 11.84QKK809 pKa = 10.71VVLCGDD815 pKa = 4.33PKK817 pKa = 10.69QCGFFNMMQMKK828 pKa = 10.04VNYY831 pKa = 8.96NHH833 pKa = 7.03NICTQVYY840 pKa = 8.57HH841 pKa = 6.56KK842 pKa = 10.5SISRR846 pKa = 11.84RR847 pKa = 11.84CTLPVTAIVSSLHH860 pKa = 5.94YY861 pKa = 8.68EE862 pKa = 4.12GKK864 pKa = 8.91MRR866 pKa = 11.84TTNEE870 pKa = 3.72YY871 pKa = 10.33NKK873 pKa = 10.0PIVVDD878 pKa = 3.57TTGSTKK884 pKa = 10.01PDD886 pKa = 3.93PGDD889 pKa = 3.52LVLTCFRR896 pKa = 11.84GWVKK900 pKa = 10.2QLQIDD905 pKa = 4.13YY906 pKa = 10.01RR907 pKa = 11.84GHH909 pKa = 5.86EE910 pKa = 4.6VMTAAASQGLTRR922 pKa = 11.84KK923 pKa = 9.35GVYY926 pKa = 9.7AVRR929 pKa = 11.84QKK931 pKa = 11.2VNEE934 pKa = 4.03NPLYY938 pKa = 10.71ASTSEE943 pKa = 4.2HH944 pKa = 6.02VNVLLTRR951 pKa = 11.84TEE953 pKa = 4.54GKK955 pKa = 10.28LVWKK959 pKa = 8.4TLSGDD964 pKa = 3.34PWIKK968 pKa = 9.53TLQNPPKK975 pKa = 10.2GNFKK979 pKa = 9.97ATIKK983 pKa = 9.77EE984 pKa = 4.2WEE986 pKa = 4.29VEE988 pKa = 4.18HH989 pKa = 7.25ASIMAGICSHH999 pKa = 6.28QMTFDD1004 pKa = 3.73TFQNKK1009 pKa = 10.04ANVCWAKK1016 pKa = 10.74SLVPILEE1023 pKa = 4.19TAGIKK1028 pKa = 10.81LNDD1031 pKa = 4.1RR1032 pKa = 11.84QWSQIIQAFKK1042 pKa = 10.33EE1043 pKa = 4.09DD1044 pKa = 3.45KK1045 pKa = 10.61AYY1047 pKa = 10.86SPEE1050 pKa = 3.86VALNEE1055 pKa = 3.91ICTRR1059 pKa = 11.84MYY1061 pKa = 11.03GVDD1064 pKa = 3.89LDD1066 pKa = 4.2SGLFSKK1072 pKa = 10.66PLVSVYY1078 pKa = 10.68YY1079 pKa = 10.89ADD1081 pKa = 3.75NHH1083 pKa = 5.73WDD1085 pKa = 3.46NRR1087 pKa = 11.84PGGKK1091 pKa = 8.46MFGFNPEE1098 pKa = 3.65AASILEE1104 pKa = 3.99RR1105 pKa = 11.84KK1106 pKa = 9.93YY1107 pKa = 10.99PFTKK1111 pKa = 10.58GKK1113 pKa = 9.67WNINKK1118 pKa = 8.97QICVTTRR1125 pKa = 11.84RR1126 pKa = 11.84IEE1128 pKa = 4.32DD1129 pKa = 3.73FNPTTNIIPANRR1141 pKa = 11.84RR1142 pKa = 11.84LPHH1145 pKa = 6.16SLVAEE1150 pKa = 3.99HH1151 pKa = 6.86RR1152 pKa = 11.84PVKK1155 pKa = 9.89GEE1157 pKa = 3.78RR1158 pKa = 11.84MEE1160 pKa = 4.03WLVNKK1165 pKa = 10.26INGHH1169 pKa = 5.6HH1170 pKa = 6.21VLLVSGCSLALPTKK1184 pKa = 9.67RR1185 pKa = 11.84VTWVAPLGVRR1195 pKa = 11.84GADD1198 pKa = 3.16YY1199 pKa = 9.45TYY1201 pKa = 11.11NLEE1204 pKa = 4.52LGLPATLGRR1213 pKa = 11.84YY1214 pKa = 9.59DD1215 pKa = 3.65LVVINIHH1222 pKa = 4.59TPFRR1226 pKa = 11.84IHH1228 pKa = 7.56HH1229 pKa = 5.48YY1230 pKa = 7.03QQCVDD1235 pKa = 3.83HH1236 pKa = 6.91AMKK1239 pKa = 10.65LQMLGGDD1246 pKa = 4.13SLRR1249 pKa = 11.84LLKK1252 pKa = 10.67PGGSLLIRR1260 pKa = 11.84AYY1262 pKa = 10.33GYY1264 pKa = 11.26ADD1266 pKa = 3.51RR1267 pKa = 11.84TSEE1270 pKa = 4.78RR1271 pKa = 11.84VICVLGRR1278 pKa = 11.84KK1279 pKa = 8.66FRR1281 pKa = 11.84SSRR1284 pKa = 11.84ALKK1287 pKa = 9.52PPCVTSNTEE1296 pKa = 3.8MFFLFSNFDD1305 pKa = 3.08NGRR1308 pKa = 11.84RR1309 pKa = 11.84NFTTHH1314 pKa = 5.81VMNNQLNAAFVGQATRR1330 pKa = 11.84AGCAPSYY1337 pKa = 9.65RR1338 pKa = 11.84VKK1340 pKa = 11.0RR1341 pKa = 11.84MDD1343 pKa = 2.9IAKK1346 pKa = 10.0NDD1348 pKa = 3.66EE1349 pKa = 4.2EE1350 pKa = 4.92CVVNAANPRR1359 pKa = 11.84GLPGDD1364 pKa = 4.44GVCKK1368 pKa = 10.1AVYY1371 pKa = 9.84KK1372 pKa = 10.34KK1373 pKa = 9.98WPEE1376 pKa = 3.94SFKK1379 pKa = 11.38NSATPVGTAKK1389 pKa = 9.87TVMCGTYY1396 pKa = 10.03PVIHH1400 pKa = 6.45AVGPNFSNYY1409 pKa = 9.69SEE1411 pKa = 4.63SEE1413 pKa = 3.66GDD1415 pKa = 3.53RR1416 pKa = 11.84EE1417 pKa = 3.62LAAAYY1422 pKa = 10.24RR1423 pKa = 11.84EE1424 pKa = 4.22VAKK1427 pKa = 10.46EE1428 pKa = 3.87VTRR1431 pKa = 11.84LGVNSVAIPLLSTGVYY1447 pKa = 10.21SGGKK1451 pKa = 9.62DD1452 pKa = 3.45RR1453 pKa = 11.84LTQSLNHH1460 pKa = 6.93LFTAMDD1466 pKa = 3.63STDD1469 pKa = 3.89ADD1471 pKa = 3.74VVIYY1475 pKa = 10.73CRR1477 pKa = 11.84DD1478 pKa = 3.59KK1479 pKa = 10.36EE1480 pKa = 4.32WEE1482 pKa = 4.19KK1483 pKa = 11.04KK1484 pKa = 9.68ISEE1487 pKa = 4.93AIQMRR1492 pKa = 11.84TQVEE1496 pKa = 4.21LLDD1499 pKa = 3.54EE1500 pKa = 5.56HH1501 pKa = 8.8ISIDD1505 pKa = 3.64CDD1507 pKa = 3.66VVRR1510 pKa = 11.84VHH1512 pKa = 7.26PDD1514 pKa = 2.45SSLAGRR1520 pKa = 11.84KK1521 pKa = 9.42GYY1523 pKa = 8.36STTEE1527 pKa = 3.71GALYY1531 pKa = 10.31SYY1533 pKa = 11.57LEE1535 pKa = 4.17GTRR1538 pKa = 11.84FHH1540 pKa = 5.73QTAVDD1545 pKa = 3.47MAEE1548 pKa = 4.87IYY1550 pKa = 10.2TMWPKK1555 pKa = 8.91QTEE1558 pKa = 4.12ANEE1561 pKa = 4.2QVCLYY1566 pKa = 10.84ALGEE1570 pKa = 4.37SIEE1573 pKa = 4.74SIRR1576 pKa = 11.84QKK1578 pKa = 11.02CPVDD1582 pKa = 3.92DD1583 pKa = 5.4ADD1585 pKa = 4.43ASSPPKK1591 pKa = 9.7TVPCLCRR1598 pKa = 11.84YY1599 pKa = 10.43AMTPEE1604 pKa = 3.81RR1605 pKa = 11.84VTRR1608 pKa = 11.84LRR1610 pKa = 11.84MNHH1613 pKa = 4.06VTSIIVCSSFPLPKK1627 pKa = 10.41YY1628 pKa = 10.29KK1629 pKa = 9.92IEE1631 pKa = 4.16GVQKK1635 pKa = 9.04VKK1637 pKa = 10.49CSKK1640 pKa = 11.01VMLFDD1645 pKa = 4.55HH1646 pKa = 6.53NVPSRR1651 pKa = 11.84VSPRR1655 pKa = 11.84EE1656 pKa = 3.61YY1657 pKa = 10.28RR1658 pKa = 11.84PSQEE1662 pKa = 4.25SVQEE1666 pKa = 4.02ASTTTSLTHH1675 pKa = 5.69SQFDD1679 pKa = 3.69LSVDD1683 pKa = 3.73GKK1685 pKa = 10.25ILPVPSDD1692 pKa = 4.02LDD1694 pKa = 3.52ADD1696 pKa = 4.07APALEE1701 pKa = 4.6PALDD1705 pKa = 4.54DD1706 pKa = 4.45GAIHH1710 pKa = 6.58TLPSATGNLAAVSDD1724 pKa = 4.31WVMSTVPVAPPRR1736 pKa = 11.84RR1737 pKa = 11.84RR1738 pKa = 11.84RR1739 pKa = 11.84GRR1741 pKa = 11.84NLTVTCDD1748 pKa = 3.35EE1749 pKa = 4.52RR1750 pKa = 11.84EE1751 pKa = 4.26GNITPMASVRR1761 pKa = 11.84FFRR1764 pKa = 11.84AEE1766 pKa = 3.77LCPVVQEE1773 pKa = 4.24TAEE1776 pKa = 4.17TRR1778 pKa = 11.84DD1779 pKa = 3.42TAMSLQAPPSTATEE1793 pKa = 4.29LSHH1796 pKa = 7.01PPISFGAPSEE1806 pKa = 4.26TFPITFGDD1814 pKa = 3.89FNEE1817 pKa = 4.75GEE1819 pKa = 4.24IEE1821 pKa = 4.26SLSSEE1826 pKa = 4.39LLTFGDD1832 pKa = 4.47FLPGEE1837 pKa = 4.34VDD1839 pKa = 5.56DD1840 pKa = 5.32LTDD1843 pKa = 4.47SDD1845 pKa = 4.31WSTCSDD1851 pKa = 3.35TDD1853 pKa = 4.25DD1854 pKa = 3.88EE1855 pKa = 5.02LRR1857 pKa = 11.84LDD1859 pKa = 3.57RR1860 pKa = 11.84AGGYY1864 pKa = 9.54IFSSDD1869 pKa = 3.41TGPGHH1874 pKa = 7.3LQQKK1878 pKa = 7.61SVRR1881 pKa = 11.84QSVLPVNTLEE1891 pKa = 4.17EE1892 pKa = 4.1VHH1894 pKa = 6.58EE1895 pKa = 4.62EE1896 pKa = 3.51KK1897 pKa = 10.63CYY1899 pKa = 10.12PPKK1902 pKa = 10.47LDD1904 pKa = 3.55EE1905 pKa = 5.06AKK1907 pKa = 10.57EE1908 pKa = 3.83QLLLKK1913 pKa = 10.21KK1914 pKa = 9.82LQEE1917 pKa = 4.38SASMANRR1924 pKa = 11.84SRR1926 pKa = 11.84YY1927 pKa = 7.57QSRR1930 pKa = 11.84KK1931 pKa = 7.68VEE1933 pKa = 4.04NMKK1936 pKa = 9.53ATIIQRR1942 pKa = 11.84LKK1944 pKa = 10.38RR1945 pKa = 11.84GCRR1948 pKa = 11.84LYY1950 pKa = 11.5LMSEE1954 pKa = 4.31TPKK1957 pKa = 10.17VPTYY1961 pKa = 9.1RR1962 pKa = 11.84TTYY1965 pKa = 8.09PAPVYY1970 pKa = 10.45SPPINVRR1977 pKa = 11.84LSNPEE1982 pKa = 3.89SAVAACNEE1990 pKa = 3.94FLARR1994 pKa = 11.84NYY1996 pKa = 7.3PTVSSYY2002 pKa = 11.24QITDD2006 pKa = 3.21EE2007 pKa = 4.02YY2008 pKa = 11.39DD2009 pKa = 3.05AYY2011 pKa = 11.6LDD2013 pKa = 3.71MVDD2016 pKa = 4.74GSEE2019 pKa = 4.23SCLDD2023 pKa = 3.09RR2024 pKa = 11.84ATFNPSKK2031 pKa = 10.39LRR2033 pKa = 11.84SYY2035 pKa = 10.03PKK2037 pKa = 8.94QHH2039 pKa = 6.99AYY2041 pKa = 9.55HH2042 pKa = 6.6APSIRR2047 pKa = 11.84SAVPSPFQNTLQNVLAAATKK2067 pKa = 9.91RR2068 pKa = 11.84NCNVTQMRR2076 pKa = 11.84EE2077 pKa = 4.06LPTLDD2082 pKa = 3.17SAVFNVEE2089 pKa = 3.96CFKK2092 pKa = 11.11KK2093 pKa = 10.16FACNQEE2099 pKa = 3.9YY2100 pKa = 9.1WEE2102 pKa = 4.7EE2103 pKa = 4.14FAASPIRR2110 pKa = 11.84ITTEE2114 pKa = 3.32NLTTYY2119 pKa = 7.64VTKK2122 pKa = 11.01LKK2124 pKa = 10.51GPKK2127 pKa = 9.28AAALFAKK2134 pKa = 8.12THH2136 pKa = 6.13NLLPLQEE2143 pKa = 4.25VPMDD2147 pKa = 3.95RR2148 pKa = 11.84FTVDD2152 pKa = 2.78MKK2154 pKa = 11.01RR2155 pKa = 11.84DD2156 pKa = 3.64VKK2158 pKa = 9.76VTPGTKK2164 pKa = 8.49HH2165 pKa = 4.48TEE2167 pKa = 3.91EE2168 pKa = 4.12RR2169 pKa = 11.84PKK2171 pKa = 10.92VQVIQAAEE2179 pKa = 3.99PLATAYY2185 pKa = 10.83LCGIHH2190 pKa = 6.74RR2191 pKa = 11.84EE2192 pKa = 4.01LVRR2195 pKa = 11.84RR2196 pKa = 11.84LNAVLLPNVHH2206 pKa = 6.22TLFDD2210 pKa = 3.67MSAEE2214 pKa = 4.19DD2215 pKa = 3.8FDD2217 pKa = 6.49AIIAAHH2223 pKa = 6.69FKK2225 pKa = 10.85PGDD2228 pKa = 3.66TVLEE2232 pKa = 3.93TDD2234 pKa = 3.31IASFDD2239 pKa = 3.58KK2240 pKa = 11.43SQDD2243 pKa = 3.31DD2244 pKa = 4.12SLALTALMLLEE2255 pKa = 4.9DD2256 pKa = 4.56LGVDD2260 pKa = 4.11HH2261 pKa = 7.19SLLDD2265 pKa = 4.47LIEE2268 pKa = 4.24AAFGEE2273 pKa = 4.67ISSCHH2278 pKa = 6.67LPTGTRR2284 pKa = 11.84FKK2286 pKa = 10.46FGAMMKK2292 pKa = 10.15SGMFLTLFVNTLLNITIASRR2312 pKa = 11.84VLEE2315 pKa = 4.2DD2316 pKa = 4.17RR2317 pKa = 11.84LTKK2320 pKa = 10.17SACAAFIGDD2329 pKa = 4.26DD2330 pKa = 4.09NIIHH2334 pKa = 6.12GVVSDD2339 pKa = 3.78EE2340 pKa = 5.12LMAARR2345 pKa = 11.84CATWMNMEE2353 pKa = 4.34VKK2355 pKa = 10.26IIDD2358 pKa = 3.57AVVSQKK2364 pKa = 10.95APYY2367 pKa = 9.15FCGGFILHH2375 pKa = 7.32DD2376 pKa = 3.66IVTGTACRR2384 pKa = 11.84VADD2387 pKa = 3.75PLKK2390 pKa = 10.79RR2391 pKa = 11.84LFKK2394 pKa = 10.55LGKK2397 pKa = 8.58PLAAGDD2403 pKa = 3.97EE2404 pKa = 4.1QDD2406 pKa = 3.2EE2407 pKa = 4.25DD2408 pKa = 3.67RR2409 pKa = 11.84RR2410 pKa = 11.84RR2411 pKa = 11.84ALADD2415 pKa = 3.31EE2416 pKa = 4.34VVRR2419 pKa = 11.84WQRR2422 pKa = 11.84TGLIDD2427 pKa = 3.77EE2428 pKa = 4.99LEE2430 pKa = 4.07KK2431 pKa = 10.82AVYY2434 pKa = 9.74SRR2436 pKa = 11.84YY2437 pKa = 8.65EE2438 pKa = 3.64VQGISVVVMSMATFASSRR2456 pKa = 11.84SNFEE2460 pKa = 3.94KK2461 pKa = 10.76LRR2463 pKa = 11.84GPVVTLYY2470 pKa = 10.79GGPKK2474 pKa = 9.71

Molecular weight:
275.65 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|Q8JUX5|POLS_CHIKS Structural polyprotein OS=Chikungunya virus (strain S27-African prototype) OX=371094 PE=1 SV=3
MM1 pKa = 7.53EE2 pKa = 6.45FIPTQTFYY10 pKa = 11.35NRR12 pKa = 11.84RR13 pKa = 11.84YY14 pKa = 9.4QPRR17 pKa = 11.84PWTPRR22 pKa = 11.84PTIQVIRR29 pKa = 11.84PRR31 pKa = 11.84PRR33 pKa = 11.84PQRR36 pKa = 11.84QAGQLAQLISAVNKK50 pKa = 8.34LTMRR54 pKa = 11.84AVPQQKK60 pKa = 9.11PRR62 pKa = 11.84KK63 pKa = 7.98NRR65 pKa = 11.84KK66 pKa = 8.2NKK68 pKa = 9.47KK69 pKa = 9.23QKK71 pKa = 10.02QKK73 pKa = 10.37QQAPQNNTNQKK84 pKa = 9.4KK85 pKa = 9.28QPPKK89 pKa = 10.4KK90 pKa = 10.39KK91 pKa = 9.51PAQKK95 pKa = 9.91KK96 pKa = 8.43KK97 pKa = 10.12KK98 pKa = 7.72PGRR101 pKa = 11.84RR102 pKa = 11.84EE103 pKa = 3.79RR104 pKa = 11.84MCMKK108 pKa = 10.15IEE110 pKa = 3.99NDD112 pKa = 4.0CIFEE116 pKa = 4.27VKK118 pKa = 10.55HH119 pKa = 5.59EE120 pKa = 4.41GKK122 pKa = 8.61VTGYY126 pKa = 10.98ACLVGDD132 pKa = 4.21KK133 pKa = 10.61VMKK136 pKa = 8.86PAHH139 pKa = 5.89VKK141 pKa = 9.19GTIDD145 pKa = 3.59NADD148 pKa = 3.75LAKK151 pKa = 10.65LAFKK155 pKa = 10.65RR156 pKa = 11.84SSKK159 pKa = 10.94YY160 pKa = 10.36DD161 pKa = 3.63LEE163 pKa = 4.52CAQIPVHH170 pKa = 5.97MKK172 pKa = 10.09SDD174 pKa = 3.34ASKK177 pKa = 8.77FTHH180 pKa = 6.46EE181 pKa = 4.66KK182 pKa = 10.19PEE184 pKa = 4.56GYY186 pKa = 10.58YY187 pKa = 9.82NWHH190 pKa = 6.9HH191 pKa = 6.54GAVQYY196 pKa = 11.02SGGRR200 pKa = 11.84FTIPTGAGKK209 pKa = 9.46PGDD212 pKa = 3.72SGRR215 pKa = 11.84PIFDD219 pKa = 3.06NKK221 pKa = 9.91GRR223 pKa = 11.84VVAIVLGGANEE234 pKa = 4.29GARR237 pKa = 11.84TALSVVTWNKK247 pKa = 10.96DD248 pKa = 2.61IVTKK252 pKa = 9.69ITPEE256 pKa = 4.05GAEE259 pKa = 4.2EE260 pKa = 3.97WSLAIPVMCLLANTTFPCSQPPCIPCCYY288 pKa = 9.32EE289 pKa = 4.01KK290 pKa = 10.89EE291 pKa = 4.26PEE293 pKa = 3.85EE294 pKa = 3.99TLRR297 pKa = 11.84MLEE300 pKa = 4.26DD301 pKa = 3.12NVMRR305 pKa = 11.84PGYY308 pKa = 9.51YY309 pKa = 9.71QLLQASLTCSPHH321 pKa = 5.23RR322 pKa = 11.84QRR324 pKa = 11.84RR325 pKa = 11.84STKK328 pKa = 10.94DD329 pKa = 2.82NFNVYY334 pKa = 9.97KK335 pKa = 10.01ATRR338 pKa = 11.84PYY340 pKa = 10.42LAHH343 pKa = 7.05CPDD346 pKa = 4.26CGEE349 pKa = 4.17GHH351 pKa = 6.19SCHH354 pKa = 6.99SPVALEE360 pKa = 4.49RR361 pKa = 11.84IRR363 pKa = 11.84NEE365 pKa = 3.94ATDD368 pKa = 4.0GTLKK372 pKa = 10.45IQVSLQIGIGTDD384 pKa = 4.5DD385 pKa = 3.41SHH387 pKa = 7.92DD388 pKa = 3.72WTKK391 pKa = 10.93LRR393 pKa = 11.84YY394 pKa = 8.28MDD396 pKa = 3.37NHH398 pKa = 6.67IPADD402 pKa = 3.56AGRR405 pKa = 11.84AGLFVRR411 pKa = 11.84TSAPCTITGTMGHH424 pKa = 7.1FILARR429 pKa = 11.84CPKK432 pKa = 10.69GEE434 pKa = 4.03TLTVGFTDD442 pKa = 3.14SRR444 pKa = 11.84KK445 pKa = 9.01ISHH448 pKa = 6.31SCTHH452 pKa = 7.21PFHH455 pKa = 7.4HH456 pKa = 7.68DD457 pKa = 3.17PPVIGRR463 pKa = 11.84EE464 pKa = 4.1KK465 pKa = 9.66FHH467 pKa = 7.17SRR469 pKa = 11.84PQHH472 pKa = 5.78GKK474 pKa = 9.08EE475 pKa = 4.54LPCSTYY481 pKa = 10.26VQSNAATAEE490 pKa = 4.28EE491 pKa = 5.07IEE493 pKa = 4.5VHH495 pKa = 5.84MPPDD499 pKa = 3.81TPDD502 pKa = 3.18RR503 pKa = 11.84TLLSQQSGNVKK514 pKa = 8.59ITVNSQTVRR523 pKa = 11.84YY524 pKa = 8.89KK525 pKa = 10.84CNCGGSNEE533 pKa = 4.16GLITTDD539 pKa = 4.68KK540 pKa = 11.08VINNCKK546 pKa = 9.79VDD548 pKa = 3.46QCHH551 pKa = 6.4AAVTNHH557 pKa = 6.74KK558 pKa = 8.99KK559 pKa = 8.42WQYY562 pKa = 10.96NSPLVPRR569 pKa = 11.84NAEE572 pKa = 3.79LGDD575 pKa = 3.69RR576 pKa = 11.84KK577 pKa = 10.66GKK579 pKa = 9.42IHH581 pKa = 7.24IPFPLANVTCMVPKK595 pKa = 10.38ARR597 pKa = 11.84NPTVTYY603 pKa = 10.35GKK605 pKa = 9.43NQVIMLLYY613 pKa = 9.43PDD615 pKa = 4.97HH616 pKa = 7.09PTLLSYY622 pKa = 10.99RR623 pKa = 11.84SMGEE627 pKa = 3.62EE628 pKa = 3.73PNYY631 pKa = 9.25QEE633 pKa = 4.3EE634 pKa = 5.1WVTHH638 pKa = 5.19KK639 pKa = 10.98KK640 pKa = 10.2EE641 pKa = 4.14VVLTVPTEE649 pKa = 4.09GLEE652 pKa = 4.34VTWGNNEE659 pKa = 3.98PYY661 pKa = 10.14KK662 pKa = 10.65YY663 pKa = 9.63WPQLSANGTAHH674 pKa = 6.55GHH676 pKa = 4.38PHH678 pKa = 7.05EE679 pKa = 5.48IILYY683 pKa = 8.85YY684 pKa = 10.45YY685 pKa = 9.98EE686 pKa = 5.75LYY688 pKa = 8.61PTMTVVVVSVASFILLSMVGMAVGMCMCARR718 pKa = 11.84RR719 pKa = 11.84RR720 pKa = 11.84CITPYY725 pKa = 10.49EE726 pKa = 4.17LTPGATVPFLLSLICCIRR744 pKa = 11.84TAKK747 pKa = 10.21AATYY751 pKa = 10.29QEE753 pKa = 3.99AAVYY757 pKa = 9.23LWNEE761 pKa = 3.84QQPLFWLQALIPLAALIVLCNCLRR785 pKa = 11.84LLPCCCKK792 pKa = 9.93TLAFLSRR799 pKa = 11.84NEE801 pKa = 4.07HH802 pKa = 6.21RR803 pKa = 11.84CPHH806 pKa = 6.31CEE808 pKa = 3.48RR809 pKa = 11.84VRR811 pKa = 11.84TRR813 pKa = 11.84NSDD816 pKa = 3.68PEE818 pKa = 4.68HH819 pKa = 6.64GGSTVV824 pKa = 2.72

Molecular weight:
92.62 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

4546

824

2474

1515.3

168.8

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.985 ± 0.375

3.234 ± 0.468

4.641 ± 0.736

5.719 ± 0.4

2.926 ± 0.238

5.763 ± 0.221

2.926 ± 0.37

4.553 ± 0.166

6.005 ± 0.336

7.831 ± 0.626

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.464 ± 0.011

4.092 ± 0.289

6.445 ± 0.7

3.894 ± 0.345

5.719 ± 0.37

6.115 ± 0.503

7.193 ± 0.116

7.809 ± 0.358

1.122 ± 0.085

3.564 ± 0.142

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski