Amino acid dipepetide frequency for Tuber aestivum virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.424AlaAla: 5.424 ± 2.402
0.678AlaCys: 0.678 ± 0.56
4.068AlaAsp: 4.068 ± 0.799
3.39AlaGlu: 3.39 ± 1.762
2.034AlaPhe: 2.034 ± 0.641
3.39AlaGly: 3.39 ± 0.721
0.0AlaHis: 0.0 ± 0.0
5.424AlaIle: 5.424 ± 1.362
4.746AlaLys: 4.746 ± 1.279
6.78AlaLeu: 6.78 ± 0.402
2.034AlaMet: 2.034 ± 1.44
4.746AlaAsn: 4.746 ± 0.239
1.356AlaPro: 1.356 ± 0.08
2.712AlaGln: 2.712 ± 0.161
2.712AlaArg: 2.712 ± 0.88
4.068AlaSer: 4.068 ± 0.799
2.712AlaThr: 2.712 ± 0.88
9.492AlaVal: 9.492 ± 2.558
2.712AlaTrp: 2.712 ± 1.201
3.39AlaTyr: 3.39 ± 0.319
0.0AlaXaa: 0.0 ± 0.0
Cys
2.034CysAla: 2.034 ± 1.44
0.0CysCys: 0.0 ± 0.0
0.678CysAsp: 0.678 ± 0.48
0.678CysGlu: 0.678 ± 0.48
1.356CysPhe: 1.356 ± 0.96
0.678CysGly: 0.678 ± 0.56
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.356CysLeu: 1.356 ± 0.96
0.0CysMet: 0.0 ± 0.0
0.678CysAsn: 0.678 ± 0.48
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.356CysArg: 1.356 ± 0.96
1.356CysSer: 1.356 ± 0.96
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.356CysTyr: 1.356 ± 0.08
0.0CysXaa: 0.0 ± 0.0
Asp
2.712AspAla: 2.712 ± 1.92
0.0AspCys: 0.0 ± 0.0
5.424AspAsp: 5.424 ± 1.759
2.712AspGlu: 2.712 ± 1.201
2.712AspPhe: 2.712 ± 1.201
5.424AspGly: 5.424 ± 1.362
0.0AspHis: 0.0 ± 0.0
2.034AspIle: 2.034 ± 0.641
0.678AspLys: 0.678 ± 0.48
4.746AspLeu: 4.746 ± 0.239
0.678AspMet: 0.678 ± 0.48
2.712AspAsn: 2.712 ± 1.201
1.356AspPro: 1.356 ± 0.96
1.356AspGln: 1.356 ± 0.08
1.356AspArg: 1.356 ± 0.08
5.424AspSer: 5.424 ± 2.402
1.356AspThr: 1.356 ± 0.08
7.458AspVal: 7.458 ± 1.118
2.034AspTrp: 2.034 ± 0.641
4.746AspTyr: 4.746 ± 0.239
0.0AspXaa: 0.0 ± 0.0
Glu
4.746GluAla: 4.746 ± 0.239
0.0GluCys: 0.0 ± 0.0
0.678GluAsp: 0.678 ± 0.56
2.034GluGlu: 2.034 ± 0.4
0.678GluPhe: 0.678 ± 0.48
3.39GluGly: 3.39 ± 1.762
0.678GluHis: 0.678 ± 0.48
4.068GluIle: 4.068 ± 1.282
1.356GluLys: 1.356 ± 0.96
4.746GluLeu: 4.746 ± 0.239
1.356GluMet: 1.356 ± 0.873
2.034GluAsn: 2.034 ± 0.641
1.356GluPro: 1.356 ± 0.08
2.712GluGln: 2.712 ± 1.92
3.39GluArg: 3.39 ± 0.319
1.356GluSer: 1.356 ± 0.96
2.034GluThr: 2.034 ± 0.641
2.712GluVal: 2.712 ± 0.161
4.746GluTrp: 4.746 ± 2.32
2.034GluTyr: 2.034 ± 0.4
0.0GluXaa: 0.0 ± 0.0
Phe
4.068PheAla: 4.068 ± 0.241
1.356PheCys: 1.356 ± 0.96
1.356PheAsp: 1.356 ± 0.08
1.356PheGlu: 1.356 ± 0.08
0.0PhePhe: 0.0 ± 0.0
2.034PheGly: 2.034 ± 0.641
0.0PheHis: 0.0 ± 0.0
2.034PheIle: 2.034 ± 0.4
0.678PheLys: 0.678 ± 0.56
4.068PheLeu: 4.068 ± 0.799
0.678PheMet: 0.678 ± 0.48
5.424PheAsn: 5.424 ± 0.322
1.356PhePro: 1.356 ± 0.08
0.678PheGln: 0.678 ± 0.56
2.034PheArg: 2.034 ± 0.4
1.356PheSer: 1.356 ± 0.08
1.356PheThr: 1.356 ± 1.121
2.034PheVal: 2.034 ± 0.641
1.356PheTrp: 1.356 ± 0.08
0.678PheTyr: 0.678 ± 0.56
0.0PheXaa: 0.0 ± 0.0
Gly
6.78GlyAla: 6.78 ± 2.483
1.356GlyCys: 1.356 ± 0.96
2.712GlyAsp: 2.712 ± 0.161
4.068GlyGlu: 4.068 ± 0.799
0.0GlyPhe: 0.0 ± 0.0
3.39GlyGly: 3.39 ± 1.36
0.678GlyHis: 0.678 ± 0.56
5.424GlyIle: 5.424 ± 1.362
2.034GlyLys: 2.034 ± 0.4
6.102GlyLeu: 6.102 ± 1.922
3.39GlyMet: 3.39 ± 0.721
2.034GlyAsn: 2.034 ± 0.641
1.356GlyPro: 1.356 ± 0.08
0.0GlyGln: 0.0 ± 0.0
1.356GlyArg: 1.356 ± 0.08
7.458GlySer: 7.458 ± 0.962
2.712GlyThr: 2.712 ± 0.88
5.424GlyVal: 5.424 ± 0.719
0.678GlyTrp: 0.678 ± 0.48
4.068GlyTyr: 4.068 ± 0.241
0.0GlyXaa: 0.0 ± 0.0
His
0.678HisAla: 0.678 ± 0.56
0.0HisCys: 0.0 ± 0.0
0.678HisAsp: 0.678 ± 0.48
1.356HisGlu: 1.356 ± 0.08
0.678HisPhe: 0.678 ± 0.56
1.356HisGly: 1.356 ± 0.96
1.356HisHis: 1.356 ± 0.96
0.678HisIle: 0.678 ± 0.56
0.678HisLys: 0.678 ± 0.48
2.034HisLeu: 2.034 ± 1.44
0.678HisMet: 0.678 ± 0.48
0.678HisAsn: 0.678 ± 0.48
0.678HisPro: 0.678 ± 0.56
0.678HisGln: 0.678 ± 0.56
1.356HisArg: 1.356 ± 0.96
4.068HisSer: 4.068 ± 1.84
1.356HisThr: 1.356 ± 0.96
1.356HisVal: 1.356 ± 1.121
0.0HisTrp: 0.0 ± 0.0
1.356HisTyr: 1.356 ± 0.96
0.0HisXaa: 0.0 ± 0.0
Ile
2.034IleAla: 2.034 ± 0.641
0.0IleCys: 0.0 ± 0.0
5.424IleAsp: 5.424 ± 2.402
6.102IleGlu: 6.102 ± 1.199
0.678IlePhe: 0.678 ± 0.48
4.068IleGly: 4.068 ± 0.799
0.678IleHis: 0.678 ± 0.56
2.034IleIle: 2.034 ± 0.4
3.39IleLys: 3.39 ± 1.36
1.356IleLeu: 1.356 ± 0.08
0.678IleMet: 0.678 ± 0.56
2.034IleAsn: 2.034 ± 1.681
4.068IlePro: 4.068 ± 0.241
2.712IleGln: 2.712 ± 1.201
1.356IleArg: 1.356 ± 1.121
6.102IleSer: 6.102 ± 2.239
3.39IleThr: 3.39 ± 1.36
3.39IleVal: 3.39 ± 1.762
0.0IleTrp: 0.0 ± 0.0
3.39IleTyr: 3.39 ± 1.36
0.0IleXaa: 0.0 ± 0.0
Lys
4.746LysAla: 4.746 ± 1.279
0.678LysCys: 0.678 ± 0.48
0.678LysAsp: 0.678 ± 0.48
2.034LysGlu: 2.034 ± 1.44
4.746LysPhe: 4.746 ± 0.239
2.034LysGly: 2.034 ± 0.641
2.034LysHis: 2.034 ± 0.641
3.39LysIle: 3.39 ± 1.36
0.0LysLys: 0.0 ± 0.0
2.712LysLeu: 2.712 ± 0.161
3.39LysMet: 3.39 ± 1.36
0.678LysAsn: 0.678 ± 0.56
0.678LysPro: 0.678 ± 0.56
2.034LysGln: 2.034 ± 0.641
0.678LysArg: 0.678 ± 0.48
3.39LysSer: 3.39 ± 1.36
1.356LysThr: 1.356 ± 1.121
3.39LysVal: 3.39 ± 0.319
0.0LysTrp: 0.0 ± 0.0
4.746LysTyr: 4.746 ± 0.239
0.0LysXaa: 0.0 ± 0.0
Leu
10.169LeuAla: 10.169 ± 3.204
0.0LeuCys: 0.0 ± 0.0
6.78LeuAsp: 6.78 ± 2.483
1.356LeuGlu: 1.356 ± 0.08
7.458LeuPhe: 7.458 ± 1.118
4.746LeuGly: 4.746 ± 2.32
1.356LeuHis: 1.356 ± 0.96
2.712LeuIle: 2.712 ± 1.201
2.712LeuLys: 2.712 ± 0.88
10.169LeuLeu: 10.169 ± 1.998
2.034LeuMet: 2.034 ± 0.452
5.424LeuAsn: 5.424 ± 1.362
5.424LeuPro: 5.424 ± 4.483
4.746LeuGln: 4.746 ± 0.239
6.78LeuArg: 6.78 ± 1.442
9.492LeuSer: 9.492 ± 3.599
7.458LeuThr: 7.458 ± 0.078
4.068LeuVal: 4.068 ± 1.84
0.678LeuTrp: 0.678 ± 0.56
4.068LeuTyr: 4.068 ± 0.241
0.0LeuXaa: 0.0 ± 0.0
Met
2.034MetAla: 2.034 ± 1.681
0.678MetCys: 0.678 ± 0.48
1.356MetAsp: 1.356 ± 0.96
0.678MetGlu: 0.678 ± 0.48
0.0MetPhe: 0.0 ± 0.0
0.678MetGly: 0.678 ± 0.48
1.356MetHis: 1.356 ± 0.96
2.034MetIle: 2.034 ± 0.641
0.0MetLys: 0.0 ± 0.0
4.068MetLeu: 4.068 ± 0.241
0.678MetMet: 0.678 ± 0.48
1.356MetAsn: 1.356 ± 0.96
2.712MetPro: 2.712 ± 0.161
1.356MetGln: 1.356 ± 0.96
1.356MetArg: 1.356 ± 0.96
4.068MetSer: 4.068 ± 0.799
1.356MetThr: 1.356 ± 0.08
2.712MetVal: 2.712 ± 2.242
0.0MetTrp: 0.0 ± 0.0
2.034MetTyr: 2.034 ± 0.641
0.0MetXaa: 0.0 ± 0.0
Asn
2.712AsnAla: 2.712 ± 1.201
0.678AsnCys: 0.678 ± 0.56
2.034AsnAsp: 2.034 ± 0.641
1.356AsnGlu: 1.356 ± 0.08
4.068AsnPhe: 4.068 ± 1.282
2.712AsnGly: 2.712 ± 1.201
1.356AsnHis: 1.356 ± 1.121
3.39AsnIle: 3.39 ± 1.36
2.712AsnLys: 2.712 ± 0.88
5.424AsnLeu: 5.424 ± 2.402
0.678AsnMet: 0.678 ± 0.56
0.678AsnAsn: 0.678 ± 0.56
2.712AsnPro: 2.712 ± 1.201
1.356AsnGln: 1.356 ± 1.121
2.034AsnArg: 2.034 ± 0.4
4.068AsnSer: 4.068 ± 0.241
1.356AsnThr: 1.356 ± 0.96
5.424AsnVal: 5.424 ± 1.362
0.678AsnTrp: 0.678 ± 0.48
1.356AsnTyr: 1.356 ± 1.121
0.0AsnXaa: 0.0 ± 0.0
Pro
2.034ProAla: 2.034 ± 0.641
1.356ProCys: 1.356 ± 0.96
2.712ProAsp: 2.712 ± 2.242
3.39ProGlu: 3.39 ± 1.762
1.356ProPhe: 1.356 ± 1.121
4.068ProGly: 4.068 ± 0.241
0.678ProHis: 0.678 ± 0.48
2.712ProIle: 2.712 ± 0.161
6.102ProLys: 6.102 ± 2.963
5.424ProLeu: 5.424 ± 2.402
0.0ProMet: 0.0 ± 0.0
2.034ProAsn: 2.034 ± 0.641
0.678ProPro: 0.678 ± 0.48
2.034ProGln: 2.034 ± 0.4
0.678ProArg: 0.678 ± 0.56
2.034ProSer: 2.034 ± 0.4
2.712ProThr: 2.712 ± 0.161
2.712ProVal: 2.712 ± 0.88
0.0ProTrp: 0.0 ± 0.0
1.356ProTyr: 1.356 ± 1.121
0.0ProXaa: 0.0 ± 0.0
Gln
3.39GlnAla: 3.39 ± 1.36
0.0GlnCys: 0.0 ± 0.0
0.678GlnAsp: 0.678 ± 0.56
1.356GlnGlu: 1.356 ± 0.08
0.678GlnPhe: 0.678 ± 0.56
0.678GlnGly: 0.678 ± 0.48
0.678GlnHis: 0.678 ± 0.48
0.678GlnIle: 0.678 ± 0.48
0.0GlnLys: 0.0 ± 0.0
5.424GlnLeu: 5.424 ± 1.759
0.678GlnMet: 0.678 ± 0.48
0.0GlnAsn: 0.0 ± 0.0
4.068GlnPro: 4.068 ± 1.282
2.712GlnGln: 2.712 ± 0.88
1.356GlnArg: 1.356 ± 0.96
0.678GlnSer: 0.678 ± 0.56
2.034GlnThr: 2.034 ± 1.681
4.068GlnVal: 4.068 ± 0.241
0.0GlnTrp: 0.0 ± 0.0
2.034GlnTyr: 2.034 ± 0.4
0.0GlnXaa: 0.0 ± 0.0
Arg
3.39ArgAla: 3.39 ± 1.36
1.356ArgCys: 1.356 ± 0.96
0.678ArgAsp: 0.678 ± 0.56
0.0ArgGlu: 0.0 ± 0.0
0.0ArgPhe: 0.0 ± 0.0
5.424ArgGly: 5.424 ± 1.362
0.678ArgHis: 0.678 ± 0.48
2.034ArgIle: 2.034 ± 0.4
4.068ArgLys: 4.068 ± 0.241
9.492ArgLeu: 9.492 ± 1.518
0.0ArgMet: 0.0 ± 0.0
1.356ArgAsn: 1.356 ± 0.08
0.678ArgPro: 0.678 ± 0.48
0.678ArgGln: 0.678 ± 0.56
3.39ArgArg: 3.39 ± 0.721
4.746ArgSer: 4.746 ± 2.32
4.746ArgThr: 4.746 ± 1.279
3.39ArgVal: 3.39 ± 1.36
2.034ArgTrp: 2.034 ± 0.4
2.712ArgTyr: 2.712 ± 1.201
0.0ArgXaa: 0.0 ± 0.0
Ser
4.746SerAla: 4.746 ± 1.279
1.356SerCys: 1.356 ± 0.96
4.068SerAsp: 4.068 ± 0.799
2.712SerGlu: 2.712 ± 0.161
2.712SerPhe: 2.712 ± 1.92
6.102SerGly: 6.102 ± 0.158
1.356SerHis: 1.356 ± 0.96
3.39SerIle: 3.39 ± 1.36
4.068SerLys: 4.068 ± 0.241
8.136SerLeu: 8.136 ± 3.604
3.39SerMet: 3.39 ± 0.319
3.39SerAsn: 3.39 ± 2.802
2.034SerPro: 2.034 ± 0.4
4.068SerGln: 4.068 ± 1.84
6.102SerArg: 6.102 ± 3.28
6.78SerSer: 6.78 ± 1.679
6.102SerThr: 6.102 ± 2.239
9.492SerVal: 9.492 ± 0.563
3.39SerTrp: 3.39 ± 2.802
0.678SerTyr: 0.678 ± 0.56
0.0SerXaa: 0.0 ± 0.0
Thr
3.39ThrAla: 3.39 ± 1.36
0.0ThrCys: 0.0 ± 0.0
2.712ThrAsp: 2.712 ± 0.88
2.034ThrGlu: 2.034 ± 0.4
2.034ThrPhe: 2.034 ± 0.641
2.712ThrGly: 2.712 ± 1.201
2.034ThrHis: 2.034 ± 1.44
4.068ThrIle: 4.068 ± 0.241
3.39ThrLys: 3.39 ± 1.36
5.424ThrLeu: 5.424 ± 0.719
2.712ThrMet: 2.712 ± 1.201
3.39ThrAsn: 3.39 ± 1.762
3.39ThrPro: 3.39 ± 0.721
0.678ThrGln: 0.678 ± 0.48
4.068ThrArg: 4.068 ± 0.799
4.746ThrSer: 4.746 ± 1.842
6.102ThrThr: 6.102 ± 0.882
5.424ThrVal: 5.424 ± 1.759
0.678ThrTrp: 0.678 ± 0.56
0.678ThrTyr: 0.678 ± 0.48
0.0ThrXaa: 0.0 ± 0.0
Val
3.39ValAla: 3.39 ± 1.36
1.356ValCys: 1.356 ± 0.96
6.102ValAsp: 6.102 ± 2.239
5.424ValGlu: 5.424 ± 0.719
2.034ValPhe: 2.034 ± 0.641
4.068ValGly: 4.068 ± 1.282
6.102ValHis: 6.102 ± 1.199
3.39ValIle: 3.39 ± 0.319
2.712ValLys: 2.712 ± 0.161
6.78ValLeu: 6.78 ± 0.638
3.39ValMet: 3.39 ± 0.319
4.746ValAsn: 4.746 ± 1.279
2.712ValPro: 2.712 ± 1.201
0.0ValGln: 0.0 ± 0.0
4.068ValArg: 4.068 ± 2.322
6.78ValSer: 6.78 ± 3.523
7.458ValThr: 7.458 ± 2.003
3.39ValVal: 3.39 ± 0.721
2.034ValTrp: 2.034 ± 0.641
7.458ValTyr: 7.458 ± 2.159
0.0ValXaa: 0.0 ± 0.0
Trp
2.034TrpAla: 2.034 ± 0.4
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.034TrpGlu: 2.034 ± 0.4
0.0TrpPhe: 0.0 ± 0.0
2.034TrpGly: 2.034 ± 0.641
0.0TrpHis: 0.0 ± 0.0
1.356TrpIle: 1.356 ± 0.08
0.0TrpLys: 0.0 ± 0.0
2.034TrpLeu: 2.034 ± 1.681
0.678TrpMet: 0.678 ± 0.56
1.356TrpAsn: 1.356 ± 1.121
2.034TrpPro: 2.034 ± 0.4
0.0TrpGln: 0.0 ± 0.0
1.356TrpArg: 1.356 ± 0.08
1.356TrpSer: 1.356 ± 0.08
1.356TrpThr: 1.356 ± 0.08
2.712TrpVal: 2.712 ± 0.161
0.0TrpTrp: 0.0 ± 0.0
1.356TrpTyr: 1.356 ± 0.08
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.356TyrAla: 1.356 ± 0.96
0.678TyrCys: 0.678 ± 0.48
6.102TyrAsp: 6.102 ± 0.882
2.034TyrGlu: 2.034 ± 1.44
0.678TyrPhe: 0.678 ± 0.56
2.034TyrGly: 2.034 ± 1.44
0.678TyrHis: 0.678 ± 0.48
2.034TyrIle: 2.034 ± 0.4
4.068TyrLys: 4.068 ± 0.799
2.034TyrLeu: 2.034 ± 0.4
2.712TyrMet: 2.712 ± 0.88
2.034TyrAsn: 2.034 ± 0.641
5.424TyrPro: 5.424 ± 2.402
0.678TyrGln: 0.678 ± 0.48
4.068TyrArg: 4.068 ± 1.84
4.746TyrSer: 4.746 ± 0.802
2.712TyrThr: 2.712 ± 0.161
4.746TyrVal: 4.746 ± 2.882
0.678TyrTrp: 0.678 ± 0.56
3.39TyrTyr: 3.39 ± 0.721
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski