Amino acid dipepetide frequency for Black currant nucleorhabdovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.45AlaAla: 1.45 ± 0.651
0.0AlaCys: 0.0 ± 0.0
2.417AlaAsp: 2.417 ± 0.652
3.383AlaGlu: 3.383 ± 1.539
1.933AlaPhe: 1.933 ± 1.28
2.417AlaGly: 2.417 ± 0.49
1.45AlaHis: 1.45 ± 0.391
3.383AlaIle: 3.383 ± 1.019
3.383AlaLys: 3.383 ± 1.858
3.867AlaLeu: 3.867 ± 0.345
1.208AlaMet: 1.208 ± 0.533
1.692AlaAsn: 1.692 ± 0.775
2.417AlaPro: 2.417 ± 1.446
1.45AlaGln: 1.45 ± 0.613
1.933AlaArg: 1.933 ± 0.622
5.075AlaSer: 5.075 ± 1.357
3.625AlaThr: 3.625 ± 1.487
3.142AlaVal: 3.142 ± 1.245
0.967AlaTrp: 0.967 ± 0.372
3.383AlaTyr: 3.383 ± 1.347
0.0AlaXaa: 0.0 ± 0.0
Cys
0.242CysAla: 0.242 ± 0.278
0.242CysCys: 0.242 ± 0.146
0.967CysAsp: 0.967 ± 0.407
1.45CysGlu: 1.45 ± 0.617
0.725CysPhe: 0.725 ± 0.51
1.692CysGly: 1.692 ± 0.45
0.483CysHis: 0.483 ± 0.489
1.208CysIle: 1.208 ± 0.477
1.208CysLys: 1.208 ± 0.395
1.45CysLeu: 1.45 ± 0.7
1.45CysMet: 1.45 ± 0.476
0.483CysAsn: 0.483 ± 0.252
1.208CysPro: 1.208 ± 0.374
0.483CysGln: 0.483 ± 0.376
0.242CysArg: 0.242 ± 0.146
2.658CysSer: 2.658 ± 0.78
1.208CysThr: 1.208 ± 0.401
0.967CysVal: 0.967 ± 0.462
0.0CysTrp: 0.0 ± 0.0
1.208CysTyr: 1.208 ± 0.346
0.0CysXaa: 0.0 ± 0.0
Asp
2.417AspAla: 2.417 ± 1.585
1.208AspCys: 1.208 ± 0.525
4.35AspAsp: 4.35 ± 1.46
3.142AspGlu: 3.142 ± 0.829
2.417AspPhe: 2.417 ± 0.74
2.175AspGly: 2.175 ± 0.757
3.142AspHis: 3.142 ± 0.802
6.525AspIle: 6.525 ± 1.498
4.833AspLys: 4.833 ± 1.207
6.283AspLeu: 6.283 ± 0.898
1.933AspMet: 1.933 ± 0.547
2.175AspAsn: 2.175 ± 0.862
3.625AspPro: 3.625 ± 1.198
3.142AspGln: 3.142 ± 0.628
2.175AspArg: 2.175 ± 0.825
3.383AspSer: 3.383 ± 1.239
3.142AspThr: 3.142 ± 1.611
3.142AspVal: 3.142 ± 1.0
0.483AspTrp: 0.483 ± 0.293
2.175AspTyr: 2.175 ± 0.696
0.0AspXaa: 0.0 ± 0.0
Glu
3.625GluAla: 3.625 ± 1.144
0.725GluCys: 0.725 ± 0.305
4.108GluAsp: 4.108 ± 1.026
4.833GluGlu: 4.833 ± 0.898
2.175GluPhe: 2.175 ± 0.873
4.592GluGly: 4.592 ± 0.808
0.967GluHis: 0.967 ± 0.677
5.075GluIle: 5.075 ± 1.167
4.35GluLys: 4.35 ± 1.954
5.075GluLeu: 5.075 ± 0.609
2.175GluMet: 2.175 ± 0.573
2.175GluAsn: 2.175 ± 0.67
0.967GluPro: 0.967 ± 0.493
1.933GluGln: 1.933 ± 0.504
2.175GluArg: 2.175 ± 0.623
2.658GluSer: 2.658 ± 1.391
3.383GluThr: 3.383 ± 1.838
2.658GluVal: 2.658 ± 1.121
0.967GluTrp: 0.967 ± 0.524
1.933GluTyr: 1.933 ± 0.655
0.0GluXaa: 0.0 ± 0.0
Phe
1.692PheAla: 1.692 ± 0.528
0.242PheCys: 0.242 ± 0.146
2.175PheAsp: 2.175 ± 0.924
1.208PheGlu: 1.208 ± 0.401
1.208PhePhe: 1.208 ± 0.477
1.933PheGly: 1.933 ± 1.08
0.483PheHis: 0.483 ± 0.293
2.9PheIle: 2.9 ± 0.484
2.417PheLys: 2.417 ± 0.584
3.383PheLeu: 3.383 ± 0.611
0.967PheMet: 0.967 ± 0.415
2.9PheAsn: 2.9 ± 1.268
2.417PhePro: 2.417 ± 1.058
1.692PheGln: 1.692 ± 0.833
1.933PheArg: 1.933 ± 0.724
4.108PheSer: 4.108 ± 1.247
1.933PheThr: 1.933 ± 0.717
0.967PheVal: 0.967 ± 0.594
0.483PheTrp: 0.483 ± 0.555
0.967PheTyr: 0.967 ± 0.462
0.0PheXaa: 0.0 ± 0.0
Gly
2.9GlyAla: 2.9 ± 0.845
0.483GlyCys: 0.483 ± 0.806
4.592GlyAsp: 4.592 ± 1.054
1.933GlyGlu: 1.933 ± 0.717
2.175GlyPhe: 2.175 ± 0.786
3.142GlyGly: 3.142 ± 0.439
1.208GlyHis: 1.208 ± 0.346
5.317GlyIle: 5.317 ± 0.733
4.833GlyLys: 4.833 ± 1.768
3.625GlyLeu: 3.625 ± 1.173
1.933GlyMet: 1.933 ± 0.835
2.175GlyAsn: 2.175 ± 0.674
1.208GlyPro: 1.208 ± 0.542
0.725GlyGln: 0.725 ± 0.448
1.208GlyArg: 1.208 ± 0.477
4.833GlySer: 4.833 ± 0.936
1.933GlyThr: 1.933 ± 0.427
3.383GlyVal: 3.383 ± 1.088
0.725GlyTrp: 0.725 ± 0.305
1.933GlyTyr: 1.933 ± 0.871
0.0GlyXaa: 0.0 ± 0.0
His
1.45HisAla: 1.45 ± 0.483
0.242HisCys: 0.242 ± 0.146
0.725HisAsp: 0.725 ± 0.439
2.175HisGlu: 2.175 ± 0.672
1.208HisPhe: 1.208 ± 0.481
3.625HisGly: 3.625 ± 1.155
0.483HisHis: 0.483 ± 0.293
2.175HisIle: 2.175 ± 0.807
1.45HisLys: 1.45 ± 0.334
1.933HisLeu: 1.933 ± 0.26
0.483HisMet: 0.483 ± 0.293
0.725HisAsn: 0.725 ± 0.331
0.967HisPro: 0.967 ± 0.342
0.242HisGln: 0.242 ± 0.146
0.725HisArg: 0.725 ± 0.439
1.933HisSer: 1.933 ± 0.934
1.933HisThr: 1.933 ± 0.789
0.967HisVal: 0.967 ± 0.372
0.483HisTrp: 0.483 ± 0.293
1.692HisTyr: 1.692 ± 0.571
0.0HisXaa: 0.0 ± 0.0
Ile
3.625IleAla: 3.625 ± 1.757
2.175IleCys: 2.175 ± 0.861
4.833IleAsp: 4.833 ± 1.239
2.9IleGlu: 2.9 ± 0.732
2.658IlePhe: 2.658 ± 0.939
2.9IleGly: 2.9 ± 0.735
2.175IleHis: 2.175 ± 0.545
5.8IleIle: 5.8 ± 2.315
5.317IleLys: 5.317 ± 1.73
8.7IleLeu: 8.7 ± 1.958
1.933IleMet: 1.933 ± 0.589
4.108IleAsn: 4.108 ± 1.285
4.108IlePro: 4.108 ± 1.01
2.9IleGln: 2.9 ± 0.728
2.9IleArg: 2.9 ± 0.678
5.558IleSer: 5.558 ± 0.662
5.075IleThr: 5.075 ± 1.855
2.9IleVal: 2.9 ± 0.647
1.208IleTrp: 1.208 ± 0.413
2.658IleTyr: 2.658 ± 0.667
0.0IleXaa: 0.0 ± 0.0
Lys
5.317LysAla: 5.317 ± 2.241
0.725LysCys: 0.725 ± 0.371
3.867LysAsp: 3.867 ± 1.303
5.317LysGlu: 5.317 ± 0.852
2.175LysPhe: 2.175 ± 0.9
3.142LysGly: 3.142 ± 1.013
1.692LysHis: 1.692 ± 0.8
5.317LysIle: 5.317 ± 1.098
6.767LysLys: 6.767 ± 0.57
4.833LysLeu: 4.833 ± 0.904
3.625LysMet: 3.625 ± 1.533
3.142LysAsn: 3.142 ± 0.957
1.45LysPro: 1.45 ± 1.243
2.175LysGln: 2.175 ± 0.541
4.833LysArg: 4.833 ± 0.782
5.317LysSer: 5.317 ± 1.343
3.383LysThr: 3.383 ± 1.131
5.558LysVal: 5.558 ± 0.789
0.967LysTrp: 0.967 ± 0.372
3.867LysTyr: 3.867 ± 1.287
0.0LysXaa: 0.0 ± 0.0
Leu
4.35LeuAla: 4.35 ± 1.194
1.933LeuCys: 1.933 ± 0.841
4.592LeuAsp: 4.592 ± 0.903
5.317LeuGlu: 5.317 ± 0.965
4.592LeuPhe: 4.592 ± 1.36
3.383LeuGly: 3.383 ± 1.307
2.9LeuHis: 2.9 ± 0.829
4.108LeuIle: 4.108 ± 0.806
5.558LeuLys: 5.558 ± 1.873
9.183LeuLeu: 9.183 ± 2.325
2.417LeuMet: 2.417 ± 0.379
3.383LeuAsn: 3.383 ± 0.564
3.867LeuPro: 3.867 ± 0.345
2.9LeuGln: 2.9 ± 1.175
4.592LeuArg: 4.592 ± 1.316
11.358LeuSer: 11.358 ± 1.385
5.8LeuThr: 5.8 ± 0.62
4.592LeuVal: 4.592 ± 0.69
0.725LeuTrp: 0.725 ± 0.371
5.8LeuTyr: 5.8 ± 1.394
0.0LeuXaa: 0.0 ± 0.0
Met
2.417MetAla: 2.417 ± 1.554
0.483MetCys: 0.483 ± 0.252
1.692MetAsp: 1.692 ± 0.599
1.692MetGlu: 1.692 ± 0.592
0.483MetPhe: 0.483 ± 0.326
0.967MetGly: 0.967 ± 0.74
0.725MetHis: 0.725 ± 0.371
2.9MetIle: 2.9 ± 0.957
3.625MetLys: 3.625 ± 1.73
1.45MetLeu: 1.45 ± 0.752
0.483MetMet: 0.483 ± 0.293
1.208MetAsn: 1.208 ± 0.525
0.967MetPro: 0.967 ± 0.781
0.967MetGln: 0.967 ± 0.433
2.175MetArg: 2.175 ± 0.639
4.108MetSer: 4.108 ± 0.461
2.658MetThr: 2.658 ± 0.265
1.208MetVal: 1.208 ± 0.708
0.242MetTrp: 0.242 ± 0.403
1.692MetTyr: 1.692 ± 0.579
0.0MetXaa: 0.0 ± 0.0
Asn
1.933AsnAla: 1.933 ± 0.681
0.967AsnCys: 0.967 ± 0.433
2.175AsnAsp: 2.175 ± 0.545
2.417AsnGlu: 2.417 ± 0.571
0.967AsnPhe: 0.967 ± 0.585
1.208AsnGly: 1.208 ± 1.246
1.45AsnHis: 1.45 ± 0.79
3.625AsnIle: 3.625 ± 1.466
3.867AsnLys: 3.867 ± 0.742
3.625AsnLeu: 3.625 ± 0.876
1.692AsnMet: 1.692 ± 0.571
2.175AsnAsn: 2.175 ± 1.126
2.417AsnPro: 2.417 ± 0.547
1.692AsnGln: 1.692 ± 0.909
1.45AsnArg: 1.45 ± 0.478
3.383AsnSer: 3.383 ± 0.573
3.142AsnThr: 3.142 ± 1.07
3.142AsnVal: 3.142 ± 0.867
0.0AsnTrp: 0.0 ± 0.0
2.175AsnTyr: 2.175 ± 1.069
0.0AsnXaa: 0.0 ± 0.0
Pro
1.45ProAla: 1.45 ± 1.055
0.483ProCys: 0.483 ± 0.555
3.625ProAsp: 3.625 ± 1.481
2.9ProGlu: 2.9 ± 1.492
1.208ProPhe: 1.208 ± 1.02
1.45ProGly: 1.45 ± 0.538
0.725ProHis: 0.725 ± 0.439
3.625ProIle: 3.625 ± 0.936
1.692ProLys: 1.692 ± 0.498
4.592ProLeu: 4.592 ± 1.565
1.692ProMet: 1.692 ± 0.48
1.692ProAsn: 1.692 ± 0.557
1.692ProPro: 1.692 ± 1.047
0.967ProGln: 0.967 ± 0.379
1.45ProArg: 1.45 ± 0.787
4.833ProSer: 4.833 ± 1.82
3.383ProThr: 3.383 ± 1.456
2.658ProVal: 2.658 ± 0.843
0.483ProTrp: 0.483 ± 0.47
3.142ProTyr: 3.142 ± 0.728
0.0ProXaa: 0.0 ± 0.0
Gln
1.208GlnAla: 1.208 ± 0.53
0.483GlnCys: 0.483 ± 0.326
2.175GlnAsp: 2.175 ± 0.832
2.658GlnGlu: 2.658 ± 0.683
1.208GlnPhe: 1.208 ± 0.574
1.692GlnGly: 1.692 ± 0.991
1.45GlnHis: 1.45 ± 0.83
2.417GlnIle: 2.417 ± 0.5
1.933GlnLys: 1.933 ± 0.621
2.658GlnLeu: 2.658 ± 1.092
0.967GlnMet: 0.967 ± 0.505
1.45GlnAsn: 1.45 ± 0.7
0.725GlnPro: 0.725 ± 0.396
0.967GlnGln: 0.967 ± 0.447
0.725GlnArg: 0.725 ± 0.305
3.142GlnSer: 3.142 ± 1.094
1.692GlnThr: 1.692 ± 0.97
2.175GlnVal: 2.175 ± 0.857
0.0GlnTrp: 0.0 ± 0.0
1.692GlnTyr: 1.692 ± 0.625
0.0GlnXaa: 0.0 ± 0.0
Arg
1.45ArgAla: 1.45 ± 1.021
1.208ArgCys: 1.208 ± 0.53
2.9ArgAsp: 2.9 ± 0.464
3.383ArgGlu: 3.383 ± 1.323
1.933ArgPhe: 1.933 ± 0.579
2.658ArgGly: 2.658 ± 0.788
0.725ArgHis: 0.725 ± 0.384
2.658ArgIle: 2.658 ± 1.368
2.175ArgLys: 2.175 ± 0.676
4.35ArgLeu: 4.35 ± 0.865
1.692ArgMet: 1.692 ± 0.824
2.417ArgAsn: 2.417 ± 0.584
2.417ArgPro: 2.417 ± 0.393
1.933ArgGln: 1.933 ± 0.688
2.658ArgArg: 2.658 ± 1.391
2.9ArgSer: 2.9 ± 0.993
2.417ArgThr: 2.417 ± 0.886
2.658ArgVal: 2.658 ± 0.607
0.483ArgTrp: 0.483 ± 0.252
1.208ArgTyr: 1.208 ± 0.53
0.0ArgXaa: 0.0 ± 0.0
Ser
6.283SerAla: 6.283 ± 1.649
2.9SerCys: 2.9 ± 1.015
6.042SerAsp: 6.042 ± 1.878
5.075SerGlu: 5.075 ± 1.529
3.383SerPhe: 3.383 ± 0.819
3.867SerGly: 3.867 ± 1.024
0.967SerHis: 0.967 ± 0.407
5.075SerIle: 5.075 ± 0.826
6.525SerLys: 6.525 ± 1.18
9.667SerLeu: 9.667 ± 1.568
2.658SerMet: 2.658 ± 0.682
3.625SerAsn: 3.625 ± 1.071
4.108SerPro: 4.108 ± 1.491
2.9SerGln: 2.9 ± 1.229
4.108SerArg: 4.108 ± 1.01
9.425SerSer: 9.425 ± 2.372
5.558SerThr: 5.558 ± 1.197
1.933SerVal: 1.933 ± 0.934
1.933SerTrp: 1.933 ± 0.954
5.8SerTyr: 5.8 ± 0.868
0.0SerXaa: 0.0 ± 0.0
Thr
2.9ThrAla: 2.9 ± 1.252
1.692ThrCys: 1.692 ± 0.551
4.108ThrAsp: 4.108 ± 1.022
1.692ThrGlu: 1.692 ± 0.404
1.933ThrPhe: 1.933 ± 0.579
3.625ThrGly: 3.625 ± 0.917
1.208ThrHis: 1.208 ± 0.413
5.558ThrIle: 5.558 ± 0.899
4.833ThrLys: 4.833 ± 1.839
5.558ThrLeu: 5.558 ± 1.215
1.933ThrMet: 1.933 ± 0.26
3.383ThrAsn: 3.383 ± 0.698
3.142ThrPro: 3.142 ± 0.912
0.725ThrGln: 0.725 ± 0.51
3.383ThrArg: 3.383 ± 0.592
6.042ThrSer: 6.042 ± 1.945
4.35ThrThr: 4.35 ± 0.796
2.658ThrVal: 2.658 ± 0.502
1.208ThrTrp: 1.208 ± 0.395
2.9ThrTyr: 2.9 ± 0.961
0.0ThrXaa: 0.0 ± 0.0
Val
2.175ValAla: 2.175 ± 0.825
0.967ValCys: 0.967 ± 0.505
2.658ValAsp: 2.658 ± 0.804
2.658ValGlu: 2.658 ± 1.411
1.208ValPhe: 1.208 ± 0.541
2.417ValGly: 2.417 ± 0.734
1.208ValHis: 1.208 ± 0.482
2.175ValIle: 2.175 ± 0.563
4.35ValLys: 4.35 ± 0.977
5.075ValLeu: 5.075 ± 1.296
1.45ValMet: 1.45 ± 0.497
1.208ValAsn: 1.208 ± 0.801
3.142ValPro: 3.142 ± 1.798
1.45ValGln: 1.45 ± 0.528
3.142ValArg: 3.142 ± 0.979
6.767ValSer: 6.767 ± 1.065
2.9ValThr: 2.9 ± 0.963
3.383ValVal: 3.383 ± 0.457
0.725ValTrp: 0.725 ± 0.625
2.417ValTyr: 2.417 ± 0.74
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.483TrpCys: 0.483 ± 0.823
1.208TrpAsp: 1.208 ± 0.475
1.45TrpGlu: 1.45 ± 0.476
0.483TrpPhe: 0.483 ± 0.555
1.45TrpGly: 1.45 ± 0.512
0.242TrpHis: 0.242 ± 0.278
0.725TrpIle: 0.725 ± 0.415
0.967TrpLys: 0.967 ± 0.341
1.208TrpLeu: 1.208 ± 0.683
0.483TrpMet: 0.483 ± 0.485
0.483TrpAsn: 0.483 ± 0.252
0.0TrpPro: 0.0 ± 0.0
0.725TrpGln: 0.725 ± 0.384
0.967TrpArg: 0.967 ± 0.407
0.242TrpSer: 0.242 ± 0.278
0.483TrpThr: 0.483 ± 0.252
0.242TrpVal: 0.242 ± 0.146
0.0TrpTrp: 0.0 ± 0.0
0.242TrpTyr: 0.242 ± 0.278
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.692TyrAla: 1.692 ± 0.863
1.933TyrCys: 1.933 ± 0.614
2.658TyrAsp: 2.658 ± 0.573
0.967TyrGlu: 0.967 ± 0.857
1.933TyrPhe: 1.933 ± 0.579
1.933TyrGly: 1.933 ± 0.501
1.933TyrHis: 1.933 ± 0.852
4.108TyrIle: 4.108 ± 0.917
3.383TyrLys: 3.383 ± 0.863
4.833TyrLeu: 4.833 ± 2.261
0.725TyrMet: 0.725 ± 0.396
2.9TyrAsn: 2.9 ± 1.325
2.9TyrPro: 2.9 ± 1.486
1.45TyrGln: 1.45 ± 0.614
1.45TyrArg: 1.45 ± 0.611
4.108TyrSer: 4.108 ± 1.064
4.833TyrThr: 4.833 ± 0.515
3.142TyrVal: 3.142 ± 1.449
0.0TyrTrp: 0.0 ± 0.0
2.175TyrTyr: 2.175 ± 0.576
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4139 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski