Amino acid dipepetide frequency for Nocardioides baekrokdamisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.357AlaAla: 19.357 ± 0.259
0.963AlaCys: 0.963 ± 0.037
7.821AlaAsp: 7.821 ± 0.107
7.5AlaGlu: 7.5 ± 0.125
3.677AlaPhe: 3.677 ± 0.069
11.353AlaGly: 11.353 ± 0.142
2.708AlaHis: 2.708 ± 0.057
5.791AlaIle: 5.791 ± 0.091
3.421AlaLys: 3.421 ± 0.079
12.817AlaLeu: 12.817 ± 0.152
2.905AlaMet: 2.905 ± 0.059
2.782AlaAsn: 2.782 ± 0.061
5.813AlaPro: 5.813 ± 0.108
3.742AlaGln: 3.742 ± 0.071
8.172AlaArg: 8.172 ± 0.109
7.109AlaSer: 7.109 ± 0.091
7.812AlaThr: 7.812 ± 0.121
10.845AlaVal: 10.845 ± 0.109
1.883AlaTrp: 1.883 ± 0.046
3.379AlaTyr: 3.379 ± 0.065
0.0AlaXaa: 0.0 ± 0.0
Cys
0.896CysAla: 0.896 ± 0.032
0.077CysCys: 0.077 ± 0.009
0.472CysAsp: 0.472 ± 0.022
0.361CysGlu: 0.361 ± 0.023
0.221CysPhe: 0.221 ± 0.017
0.926CysGly: 0.926 ± 0.032
0.179CysHis: 0.179 ± 0.014
0.26CysIle: 0.26 ± 0.017
0.127CysLys: 0.127 ± 0.012
0.579CysLeu: 0.579 ± 0.025
0.119CysMet: 0.119 ± 0.012
0.173CysAsn: 0.173 ± 0.015
0.485CysPro: 0.485 ± 0.026
0.219CysGln: 0.219 ± 0.015
0.469CysArg: 0.469 ± 0.021
0.465CysSer: 0.465 ± 0.025
0.498CysThr: 0.498 ± 0.026
0.598CysVal: 0.598 ± 0.027
0.114CysTrp: 0.114 ± 0.013
0.159CysTyr: 0.159 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
7.443AspAla: 7.443 ± 0.101
0.396AspCys: 0.396 ± 0.022
3.361AspAsp: 3.361 ± 0.062
3.867AspGlu: 3.867 ± 0.074
1.757AspPhe: 1.757 ± 0.046
5.445AspGly: 5.445 ± 0.085
1.387AspHis: 1.387 ± 0.038
2.339AspIle: 2.339 ± 0.062
1.349AspLys: 1.349 ± 0.04
6.754AspLeu: 6.754 ± 0.092
0.946AspMet: 0.946 ± 0.034
1.092AspAsn: 1.092 ± 0.035
3.821AspPro: 3.821 ± 0.06
1.78AspGln: 1.78 ± 0.042
4.067AspArg: 4.067 ± 0.065
2.744AspSer: 2.744 ± 0.06
2.724AspThr: 2.724 ± 0.054
5.584AspVal: 5.584 ± 0.074
0.898AspTrp: 0.898 ± 0.032
1.174AspTyr: 1.174 ± 0.038
0.0AspXaa: 0.0 ± 0.0
Glu
6.982GluAla: 6.982 ± 0.114
0.341GluCys: 0.341 ± 0.021
2.742GluAsp: 2.742 ± 0.068
2.64GluGlu: 2.64 ± 0.074
1.693GluPhe: 1.693 ± 0.043
3.773GluGly: 3.773 ± 0.075
1.39GluHis: 1.39 ± 0.039
2.892GluIle: 2.892 ± 0.055
1.422GluLys: 1.422 ± 0.045
5.912GluLeu: 5.912 ± 0.107
1.049GluMet: 1.049 ± 0.039
1.045GluAsn: 1.045 ± 0.037
2.532GluPro: 2.532 ± 0.053
1.899GluGln: 1.899 ± 0.055
4.243GluArg: 4.243 ± 0.077
2.712GluSer: 2.712 ± 0.056
2.848GluThr: 2.848 ± 0.053
4.61GluVal: 4.61 ± 0.085
0.835GluTrp: 0.835 ± 0.032
1.106GluTyr: 1.106 ± 0.04
0.0GluXaa: 0.0 ± 0.0
Phe
3.794PheAla: 3.794 ± 0.061
0.28PheCys: 0.28 ± 0.019
2.031PheAsp: 2.031 ± 0.043
1.653PheGlu: 1.653 ± 0.05
0.951PhePhe: 0.951 ± 0.037
3.392PheGly: 3.392 ± 0.063
0.683PheHis: 0.683 ± 0.029
1.13PheIle: 1.13 ± 0.04
0.73PheLys: 0.73 ± 0.029
2.643PheLeu: 2.643 ± 0.06
0.522PheMet: 0.522 ± 0.028
0.817PheAsn: 0.817 ± 0.032
1.317PhePro: 1.317 ± 0.033
0.762PheGln: 0.762 ± 0.033
1.682PheArg: 1.682 ± 0.038
1.729PheSer: 1.729 ± 0.046
1.98PheThr: 1.98 ± 0.055
2.695PheVal: 2.695 ± 0.061
0.456PheTrp: 0.456 ± 0.023
0.67PheTyr: 0.67 ± 0.03
0.0PheXaa: 0.0 ± 0.0
Gly
10.098GlyAla: 10.098 ± 0.119
0.781GlyCys: 0.781 ± 0.026
4.751GlyAsp: 4.751 ± 0.074
4.323GlyGlu: 4.323 ± 0.076
3.029GlyPhe: 3.029 ± 0.058
7.981GlyGly: 7.981 ± 0.128
2.243GlyHis: 2.243 ± 0.055
4.275GlyIle: 4.275 ± 0.067
2.468GlyLys: 2.468 ± 0.059
9.009GlyLeu: 9.009 ± 0.124
1.968GlyMet: 1.968 ± 0.053
2.074GlyAsn: 2.074 ± 0.062
4.067GlyPro: 4.067 ± 0.073
2.741GlyGln: 2.741 ± 0.062
5.99GlyArg: 5.99 ± 0.089
5.806GlySer: 5.806 ± 0.1
5.838GlyThr: 5.838 ± 0.1
7.788GlyVal: 7.788 ± 0.1
1.742GlyTrp: 1.742 ± 0.05
2.302GlyTyr: 2.302 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
2.508HisAla: 2.508 ± 0.056
0.189HisCys: 0.189 ± 0.014
1.352HisAsp: 1.352 ± 0.042
1.144HisGlu: 1.144 ± 0.033
0.689HisPhe: 0.689 ± 0.024
2.242HisGly: 2.242 ± 0.052
0.714HisHis: 0.714 ± 0.032
0.861HisIle: 0.861 ± 0.033
0.473HisLys: 0.473 ± 0.024
2.39HisLeu: 2.39 ± 0.056
0.396HisMet: 0.396 ± 0.022
0.532HisAsn: 0.532 ± 0.027
1.576HisPro: 1.576 ± 0.042
0.658HisGln: 0.658 ± 0.026
1.681HisArg: 1.681 ± 0.045
1.155HisSer: 1.155 ± 0.034
1.126HisThr: 1.126 ± 0.034
1.94HisVal: 1.94 ± 0.049
0.352HisTrp: 0.352 ± 0.022
0.486HisTyr: 0.486 ± 0.022
0.0HisXaa: 0.0 ± 0.0
Ile
6.52IleAla: 6.52 ± 0.089
0.369IleCys: 0.369 ± 0.023
3.322IleAsp: 3.322 ± 0.051
2.916IleGlu: 2.916 ± 0.062
1.155IlePhe: 1.155 ± 0.038
4.64IleGly: 4.64 ± 0.078
0.937IleHis: 0.937 ± 0.032
1.583IleIle: 1.583 ± 0.041
1.237IleLys: 1.237 ± 0.041
3.51IleLeu: 3.51 ± 0.06
0.611IleMet: 0.611 ± 0.031
1.272IleAsn: 1.272 ± 0.037
2.445IlePro: 2.445 ± 0.058
1.182IleGln: 1.182 ± 0.036
2.687IleArg: 2.687 ± 0.048
2.537IleSer: 2.537 ± 0.051
2.902IleThr: 2.902 ± 0.06
4.076IleVal: 4.076 ± 0.06
0.605IleTrp: 0.605 ± 0.027
0.838IleTyr: 0.838 ± 0.032
0.0IleXaa: 0.0 ± 0.0
Lys
3.513LysAla: 3.513 ± 0.078
0.121LysCys: 0.121 ± 0.013
1.434LysAsp: 1.434 ± 0.047
1.128LysGlu: 1.128 ± 0.038
0.693LysPhe: 0.693 ± 0.026
1.951LysGly: 1.951 ± 0.048
0.559LysHis: 0.559 ± 0.025
1.217LysIle: 1.217 ± 0.038
1.004LysLys: 1.004 ± 0.044
2.255LysLeu: 2.255 ± 0.052
0.505LysMet: 0.505 ± 0.026
0.664LysAsn: 0.664 ± 0.027
1.506LysPro: 1.506 ± 0.04
0.907LysGln: 0.907 ± 0.035
1.649LysArg: 1.649 ± 0.047
1.384LysSer: 1.384 ± 0.048
1.548LysThr: 1.548 ± 0.048
2.451LysVal: 2.451 ± 0.057
0.292LysTrp: 0.292 ± 0.021
0.633LysTyr: 0.633 ± 0.03
0.0LysXaa: 0.0 ± 0.0
Leu
13.661LeuAla: 13.661 ± 0.132
0.659LeuCys: 0.659 ± 0.027
6.117LeuAsp: 6.117 ± 0.09
4.954LeuGlu: 4.954 ± 0.078
2.602LeuPhe: 2.602 ± 0.06
8.988LeuGly: 8.988 ± 0.114
1.978LeuHis: 1.978 ± 0.054
4.409LeuIle: 4.409 ± 0.076
2.44LeuLys: 2.44 ± 0.056
9.232LeuLeu: 9.232 ± 0.136
1.916LeuMet: 1.916 ± 0.046
2.234LeuAsn: 2.234 ± 0.055
5.392LeuPro: 5.392 ± 0.083
2.66LeuGln: 2.66 ± 0.054
6.863LeuArg: 6.863 ± 0.1
5.658LeuSer: 5.658 ± 0.089
6.51LeuThr: 6.51 ± 0.091
8.757LeuVal: 8.757 ± 0.117
1.287LeuTrp: 1.287 ± 0.042
1.607LeuTyr: 1.607 ± 0.037
0.0LeuXaa: 0.0 ± 0.0
Met
2.518MetAla: 2.518 ± 0.053
0.144MetCys: 0.144 ± 0.014
0.94MetAsp: 0.94 ± 0.036
0.758MetGlu: 0.758 ± 0.032
0.596MetPhe: 0.596 ± 0.027
1.462MetGly: 1.462 ± 0.042
0.408MetHis: 0.408 ± 0.022
0.929MetIle: 0.929 ± 0.033
0.596MetLys: 0.596 ± 0.023
1.89MetLeu: 1.89 ± 0.059
0.382MetMet: 0.382 ± 0.021
0.53MetAsn: 0.53 ± 0.026
1.152MetPro: 1.152 ± 0.033
0.572MetGln: 0.572 ± 0.028
1.426MetArg: 1.426 ± 0.038
1.689MetSer: 1.689 ± 0.048
1.883MetThr: 1.883 ± 0.047
1.585MetVal: 1.585 ± 0.048
0.289MetTrp: 0.289 ± 0.018
0.337MetTyr: 0.337 ± 0.019
0.0MetXaa: 0.0 ± 0.0
Asn
2.913AsnAla: 2.913 ± 0.063
0.21AsnCys: 0.21 ± 0.015
1.342AsnAsp: 1.342 ± 0.04
0.988AsnGlu: 0.988 ± 0.034
0.691AsnPhe: 0.691 ± 0.031
2.523AsnGly: 2.523 ± 0.075
0.526AsnHis: 0.526 ± 0.023
0.92AsnIle: 0.92 ± 0.035
0.563AsnLys: 0.563 ± 0.026
2.225AsnLeu: 2.225 ± 0.051
0.402AsnMet: 0.402 ± 0.02
0.688AsnAsn: 0.688 ± 0.032
1.713AsnPro: 1.713 ± 0.043
0.736AsnGln: 0.736 ± 0.03
1.367AsnArg: 1.367 ± 0.042
1.239AsnSer: 1.239 ± 0.048
1.329AsnThr: 1.329 ± 0.041
1.973AsnVal: 1.973 ± 0.047
0.407AsnTrp: 0.407 ± 0.022
0.584AsnTyr: 0.584 ± 0.027
0.0AsnXaa: 0.0 ± 0.0
Pro
6.666ProAla: 6.666 ± 0.109
0.297ProCys: 0.297 ± 0.019
3.445ProAsp: 3.445 ± 0.061
3.225ProGlu: 3.225 ± 0.069
1.558ProPhe: 1.558 ± 0.041
5.006ProGly: 5.006 ± 0.075
1.183ProHis: 1.183 ± 0.041
2.321ProIle: 2.321 ± 0.05
1.4ProLys: 1.4 ± 0.045
4.496ProLeu: 4.496 ± 0.072
1.136ProMet: 1.136 ± 0.032
1.298ProAsn: 1.298 ± 0.036
2.215ProPro: 2.215 ± 0.061
1.498ProGln: 1.498 ± 0.038
3.07ProArg: 3.07 ± 0.058
3.238ProSer: 3.238 ± 0.06
3.902ProThr: 3.902 ± 0.069
4.614ProVal: 4.614 ± 0.075
0.9ProTrp: 0.9 ± 0.032
1.288ProTyr: 1.288 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
3.745GlnAla: 3.745 ± 0.082
0.181GlnCys: 0.181 ± 0.014
1.282GlnAsp: 1.282 ± 0.037
1.236GlnGlu: 1.236 ± 0.041
0.848GlnPhe: 0.848 ± 0.029
2.03GlnGly: 2.03 ± 0.05
0.739GlnHis: 0.739 ± 0.027
1.71GlnIle: 1.71 ± 0.041
0.782GlnLys: 0.782 ± 0.032
3.06GlnLeu: 3.06 ± 0.057
0.669GlnMet: 0.669 ± 0.029
0.669GlnAsn: 0.669 ± 0.032
1.714GlnPro: 1.714 ± 0.044
1.221GlnGln: 1.221 ± 0.048
2.363GlnArg: 2.363 ± 0.049
1.461GlnSer: 1.461 ± 0.045
1.774GlnThr: 1.774 ± 0.049
2.556GlnVal: 2.556 ± 0.051
0.521GlnTrp: 0.521 ± 0.027
0.652GlnTyr: 0.652 ± 0.026
0.0GlnXaa: 0.0 ± 0.0
Arg
7.662ArgAla: 7.662 ± 0.106
0.437ArgCys: 0.437 ± 0.02
3.863ArgAsp: 3.863 ± 0.067
3.818ArgGlu: 3.818 ± 0.073
2.027ArgPhe: 2.027 ± 0.05
5.077ArgGly: 5.077 ± 0.074
1.589ArgHis: 1.589 ± 0.049
3.409ArgIle: 3.409 ± 0.057
1.625ArgLys: 1.625 ± 0.049
7.013ArgLeu: 7.013 ± 0.107
1.674ArgMet: 1.674 ± 0.052
1.461ArgAsn: 1.461 ± 0.042
3.417ArgPro: 3.417 ± 0.065
2.044ArgGln: 2.044 ± 0.05
5.902ArgArg: 5.902 ± 0.11
3.799ArgSer: 3.799 ± 0.057
4.718ArgThr: 4.718 ± 0.08
5.369ArgVal: 5.369 ± 0.083
1.256ArgTrp: 1.256 ± 0.04
1.535ArgTyr: 1.535 ± 0.036
0.0ArgXaa: 0.0 ± 0.0
Ser
7.293SerAla: 7.293 ± 0.101
0.434SerCys: 0.434 ± 0.024
3.159SerAsp: 3.159 ± 0.066
2.572SerGlu: 2.572 ± 0.054
1.803SerPhe: 1.803 ± 0.045
5.916SerGly: 5.916 ± 0.099
1.271SerHis: 1.271 ± 0.039
2.556SerIle: 2.556 ± 0.062
1.374SerLys: 1.374 ± 0.044
5.36SerLeu: 5.36 ± 0.077
1.388SerMet: 1.388 ± 0.042
1.37SerAsn: 1.37 ± 0.042
2.967SerPro: 2.967 ± 0.069
1.681SerGln: 1.681 ± 0.046
3.512SerArg: 3.512 ± 0.067
3.55SerSer: 3.55 ± 0.086
3.908SerThr: 3.908 ± 0.079
4.882SerVal: 4.882 ± 0.082
1.048SerTrp: 1.048 ± 0.039
1.362SerTyr: 1.362 ± 0.041
0.0SerXaa: 0.0 ± 0.0
Thr
7.74ThrAla: 7.74 ± 0.109
0.519ThrCys: 0.519 ± 0.027
3.558ThrAsp: 3.558 ± 0.062
2.881ThrGlu: 2.881 ± 0.062
2.161ThrPhe: 2.161 ± 0.045
5.884ThrGly: 5.884 ± 0.079
1.413ThrHis: 1.413 ± 0.04
2.881ThrIle: 2.881 ± 0.062
1.589ThrLys: 1.589 ± 0.049
5.879ThrLeu: 5.879 ± 0.09
1.147ThrMet: 1.147 ± 0.039
1.599ThrAsn: 1.599 ± 0.047
4.095ThrPro: 4.095 ± 0.078
1.702ThrGln: 1.702 ± 0.051
3.573ThrArg: 3.573 ± 0.074
4.018ThrSer: 4.018 ± 0.072
4.285ThrThr: 4.285 ± 0.095
6.029ThrVal: 6.029 ± 0.084
1.041ThrTrp: 1.041 ± 0.036
1.811ThrTyr: 1.811 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
11.66ValAla: 11.66 ± 0.124
0.704ValCys: 0.704 ± 0.033
5.47ValAsp: 5.47 ± 0.087
4.817ValGlu: 4.817 ± 0.086
2.358ValPhe: 2.358 ± 0.05
7.45ValGly: 7.45 ± 0.099
1.809ValHis: 1.809 ± 0.046
4.419ValIle: 4.419 ± 0.078
1.937ValLys: 1.937 ± 0.048
8.822ValLeu: 8.822 ± 0.127
1.673ValMet: 1.673 ± 0.048
2.102ValAsn: 2.102 ± 0.051
4.7ValPro: 4.7 ± 0.063
2.106ValGln: 2.106 ± 0.04
6.358ValArg: 6.358 ± 0.091
4.881ValSer: 4.881 ± 0.084
5.875ValThr: 5.875 ± 0.085
8.803ValVal: 8.803 ± 0.109
1.14ValTrp: 1.14 ± 0.034
1.439ValTyr: 1.439 ± 0.042
0.0ValXaa: 0.0 ± 0.0
Trp
1.714TrpAla: 1.714 ± 0.047
0.143TrpCys: 0.143 ± 0.013
0.836TrpAsp: 0.836 ± 0.032
0.675TrpGlu: 0.675 ± 0.028
0.593TrpPhe: 0.593 ± 0.027
1.096TrpGly: 1.096 ± 0.034
0.395TrpHis: 0.395 ± 0.02
0.749TrpIle: 0.749 ± 0.028
0.397TrpLys: 0.397 ± 0.021
1.833TrpLeu: 1.833 ± 0.046
0.372TrpMet: 0.372 ± 0.021
0.425TrpAsn: 0.425 ± 0.025
0.73TrpPro: 0.73 ± 0.026
0.525TrpGln: 0.525 ± 0.023
1.17TrpArg: 1.17 ± 0.038
1.058TrpSer: 1.058 ± 0.037
1.123TrpThr: 1.123 ± 0.037
1.222TrpVal: 1.222 ± 0.048
0.402TrpTrp: 0.402 ± 0.022
0.332TrpTyr: 0.332 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.165TyrAla: 3.165 ± 0.06
0.152TyrCys: 0.152 ± 0.013
1.632TyrAsp: 1.632 ± 0.041
1.206TyrGlu: 1.206 ± 0.036
0.814TyrPhe: 0.814 ± 0.032
2.141TyrGly: 2.141 ± 0.04
0.353TyrHis: 0.353 ± 0.019
0.691TyrIle: 0.691 ± 0.03
0.479TyrLys: 0.479 ± 0.025
2.247TyrLeu: 2.247 ± 0.049
0.305TyrMet: 0.305 ± 0.018
0.515TyrAsn: 0.515 ± 0.025
1.097TyrPro: 1.097 ± 0.04
0.579TyrGln: 0.579 ± 0.025
1.451TyrArg: 1.451 ± 0.041
1.177TyrSer: 1.177 ± 0.037
1.219TyrThr: 1.219 ± 0.04
2.146TyrVal: 2.146 ± 0.056
0.322TyrTrp: 0.322 ± 0.023
0.521TyrTyr: 0.521 ± 0.027
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2935 proteins (913977 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski