Amino acid dipepetide frequency for Cerasibacillus sp. CC-CFT480

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.499AlaAla: 4.499 ± 0.091
0.605AlaCys: 0.605 ± 0.037
3.046AlaAsp: 3.046 ± 0.072
3.97AlaGlu: 3.97 ± 0.073
3.223AlaPhe: 3.223 ± 0.073
4.624AlaGly: 4.624 ± 0.091
1.183AlaHis: 1.183 ± 0.042
5.979AlaIle: 5.979 ± 0.091
4.712AlaLys: 4.712 ± 0.072
6.472AlaLeu: 6.472 ± 0.103
1.871AlaMet: 1.871 ± 0.048
2.81AlaAsn: 2.81 ± 0.069
1.868AlaPro: 1.868 ± 0.051
1.889AlaGln: 1.889 ± 0.05
2.405AlaArg: 2.405 ± 0.069
3.596AlaSer: 3.596 ± 0.062
3.486AlaThr: 3.486 ± 0.068
4.591AlaVal: 4.591 ± 0.082
0.538AlaTrp: 0.538 ± 0.028
2.289AlaTyr: 2.289 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.344CysAla: 0.344 ± 0.024
0.08CysCys: 0.08 ± 0.011
0.35CysAsp: 0.35 ± 0.02
0.381CysGlu: 0.381 ± 0.027
0.269CysPhe: 0.269 ± 0.019
0.549CysGly: 0.549 ± 0.025
0.212CysHis: 0.212 ± 0.013
0.447CysIle: 0.447 ± 0.023
0.368CysLys: 0.368 ± 0.026
0.538CysLeu: 0.538 ± 0.027
0.159CysMet: 0.159 ± 0.014
0.252CysAsn: 0.252 ± 0.019
0.324CysPro: 0.324 ± 0.029
0.264CysGln: 0.264 ± 0.02
0.226CysArg: 0.226 ± 0.018
0.409CysSer: 0.409 ± 0.024
0.382CysThr: 0.382 ± 0.023
0.393CysVal: 0.393 ± 0.022
0.046CysTrp: 0.046 ± 0.008
0.199CysTyr: 0.199 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
3.371AspAla: 3.371 ± 0.08
0.292AspCys: 0.292 ± 0.021
2.831AspAsp: 2.831 ± 0.081
4.751AspGlu: 4.751 ± 0.102
2.505AspPhe: 2.505 ± 0.06
3.303AspGly: 3.303 ± 0.073
1.063AspHis: 1.063 ± 0.032
4.739AspIle: 4.739 ± 0.083
3.866AspLys: 3.866 ± 0.089
4.777AspLeu: 4.777 ± 0.079
1.608AspMet: 1.608 ± 0.044
1.968AspAsn: 1.968 ± 0.059
1.926AspPro: 1.926 ± 0.057
1.756AspGln: 1.756 ± 0.046
2.026AspArg: 2.026 ± 0.056
2.613AspSer: 2.613 ± 0.057
2.652AspThr: 2.652 ± 0.065
3.953AspVal: 3.953 ± 0.071
0.618AspTrp: 0.618 ± 0.03
2.278AspTyr: 2.278 ± 0.049
0.0AspXaa: 0.0 ± 0.0
Glu
4.953GluAla: 4.953 ± 0.079
0.31GluCys: 0.31 ± 0.023
4.032GluAsp: 4.032 ± 0.087
7.617GluGlu: 7.617 ± 0.121
2.507GluPhe: 2.507 ± 0.063
3.918GluGly: 3.918 ± 0.068
1.66GluHis: 1.66 ± 0.047
6.266GluIle: 6.266 ± 0.087
7.933GluLys: 7.933 ± 0.111
6.738GluLeu: 6.738 ± 0.098
2.484GluMet: 2.484 ± 0.059
4.079GluAsn: 4.079 ± 0.067
1.931GluPro: 1.931 ± 0.055
3.66GluGln: 3.66 ± 0.082
3.438GluArg: 3.438 ± 0.073
3.37GluSer: 3.37 ± 0.061
3.957GluThr: 3.957 ± 0.079
4.987GluVal: 4.987 ± 0.089
0.794GluTrp: 0.794 ± 0.038
2.345GluTyr: 2.345 ± 0.061
0.0GluXaa: 0.0 ± 0.0
Phe
2.773PheAla: 2.773 ± 0.072
0.298PheCys: 0.298 ± 0.019
2.272PheAsp: 2.272 ± 0.046
2.619PheGlu: 2.619 ± 0.059
2.472PhePhe: 2.472 ± 0.069
3.233PheGly: 3.233 ± 0.064
1.147PheHis: 1.147 ± 0.039
4.588PheIle: 4.588 ± 0.098
2.616PheLys: 2.616 ± 0.057
4.751PheLeu: 4.751 ± 0.108
1.271PheMet: 1.271 ± 0.038
1.789PheAsn: 1.789 ± 0.039
1.716PhePro: 1.716 ± 0.049
1.809PheGln: 1.809 ± 0.056
1.558PheArg: 1.558 ± 0.049
3.261PheSer: 3.261 ± 0.069
2.75PheThr: 2.75 ± 0.063
2.999PheVal: 2.999 ± 0.075
0.482PheTrp: 0.482 ± 0.026
1.776PheTyr: 1.776 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
4.352GlyAla: 4.352 ± 0.077
0.502GlyCys: 0.502 ± 0.027
3.088GlyAsp: 3.088 ± 0.071
4.378GlyGlu: 4.378 ± 0.078
3.469GlyPhe: 3.469 ± 0.082
4.443GlyGly: 4.443 ± 0.095
1.316GlyHis: 1.316 ± 0.042
6.298GlyIle: 6.298 ± 0.101
5.498GlyLys: 5.498 ± 0.082
6.036GlyLeu: 6.036 ± 0.095
2.104GlyMet: 2.104 ± 0.06
2.762GlyAsn: 2.762 ± 0.059
1.673GlyPro: 1.673 ± 0.046
1.898GlyGln: 1.898 ± 0.053
2.315GlyArg: 2.315 ± 0.052
3.614GlySer: 3.614 ± 0.074
3.9GlyThr: 3.9 ± 0.078
4.795GlyVal: 4.795 ± 0.08
0.701GlyTrp: 0.701 ± 0.028
2.646GlyTyr: 2.646 ± 0.065
0.0GlyXaa: 0.0 ± 0.0
His
1.415HisAla: 1.415 ± 0.04
0.162HisCys: 0.162 ± 0.014
1.174HisAsp: 1.174 ± 0.04
1.486HisGlu: 1.486 ± 0.047
1.098HisPhe: 1.098 ± 0.037
1.451HisGly: 1.451 ± 0.045
0.699HisHis: 0.699 ± 0.032
1.868HisIle: 1.868 ± 0.051
1.131HisLys: 1.131 ± 0.038
2.241HisLeu: 2.241 ± 0.055
0.56HisMet: 0.56 ± 0.025
0.77HisAsn: 0.77 ± 0.034
1.229HisPro: 1.229 ± 0.039
0.91HisGln: 0.91 ± 0.031
0.847HisArg: 0.847 ± 0.028
1.148HisSer: 1.148 ± 0.04
1.116HisThr: 1.116 ± 0.036
1.64HisVal: 1.64 ± 0.043
0.2HisTrp: 0.2 ± 0.017
0.931HisTyr: 0.931 ± 0.03
0.0HisXaa: 0.0 ± 0.0
Ile
6.191IleAla: 6.191 ± 0.105
0.612IleCys: 0.612 ± 0.028
4.863IleAsp: 4.863 ± 0.078
5.983IleGlu: 5.983 ± 0.088
3.865IlePhe: 3.865 ± 0.079
6.622IleGly: 6.622 ± 0.108
2.003IleHis: 2.003 ± 0.049
7.573IleIle: 7.573 ± 0.121
5.035IleLys: 5.035 ± 0.091
7.784IleLeu: 7.784 ± 0.118
2.106IleMet: 2.106 ± 0.048
3.564IleAsn: 3.564 ± 0.071
3.826IlePro: 3.826 ± 0.071
3.505IleGln: 3.505 ± 0.071
3.221IleArg: 3.221 ± 0.076
5.47IleSer: 5.47 ± 0.096
4.842IleThr: 4.842 ± 0.067
5.876IleVal: 5.876 ± 0.1
0.732IleTrp: 0.732 ± 0.034
2.853IleTyr: 2.853 ± 0.065
0.0IleXaa: 0.0 ± 0.0
Lys
4.524LysAla: 4.524 ± 0.075
0.302LysCys: 0.302 ± 0.021
4.338LysAsp: 4.338 ± 0.072
7.968LysGlu: 7.968 ± 0.101
1.921LysPhe: 1.921 ± 0.046
4.479LysGly: 4.479 ± 0.067
1.612LysHis: 1.612 ± 0.046
5.275LysIle: 5.275 ± 0.077
6.866LysLys: 6.866 ± 0.116
5.946LysLeu: 5.946 ± 0.089
2.413LysMet: 2.413 ± 0.056
3.879LysAsn: 3.879 ± 0.077
2.216LysPro: 2.216 ± 0.054
4.048LysGln: 4.048 ± 0.08
3.604LysArg: 3.604 ± 0.064
3.671LysSer: 3.671 ± 0.085
4.071LysThr: 4.071 ± 0.091
4.6LysVal: 4.6 ± 0.089
0.818LysTrp: 0.818 ± 0.031
2.474LysTyr: 2.474 ± 0.057
0.0LysXaa: 0.0 ± 0.0
Leu
6.45LeuAla: 6.45 ± 0.095
0.546LeuCys: 0.546 ± 0.024
4.826LeuAsp: 4.826 ± 0.078
6.702LeuGlu: 6.702 ± 0.105
5.047LeuPhe: 5.047 ± 0.121
6.075LeuGly: 6.075 ± 0.09
2.034LeuHis: 2.034 ± 0.051
7.55LeuIle: 7.55 ± 0.124
6.554LeuLys: 6.554 ± 0.095
9.386LeuLeu: 9.386 ± 0.148
2.447LeuMet: 2.447 ± 0.062
4.078LeuAsn: 4.078 ± 0.074
3.79LeuPro: 3.79 ± 0.07
3.845LeuGln: 3.845 ± 0.074
3.361LeuArg: 3.361 ± 0.065
6.007LeuSer: 6.007 ± 0.095
5.437LeuThr: 5.437 ± 0.078
5.723LeuVal: 5.723 ± 0.094
0.736LeuTrp: 0.736 ± 0.032
3.122LeuTyr: 3.122 ± 0.067
0.0LeuXaa: 0.0 ± 0.0
Met
1.876MetAla: 1.876 ± 0.049
0.11MetCys: 0.11 ± 0.012
1.721MetAsp: 1.721 ± 0.051
2.386MetGlu: 2.386 ± 0.051
1.119MetPhe: 1.119 ± 0.032
1.774MetGly: 1.774 ± 0.045
0.499MetHis: 0.499 ± 0.023
2.362MetIle: 2.362 ± 0.05
2.706MetLys: 2.706 ± 0.05
2.494MetLeu: 2.494 ± 0.061
0.949MetMet: 0.949 ± 0.033
1.689MetAsn: 1.689 ± 0.052
0.961MetPro: 0.961 ± 0.03
0.989MetGln: 0.989 ± 0.032
1.125MetArg: 1.125 ± 0.037
1.612MetSer: 1.612 ± 0.045
1.607MetThr: 1.607 ± 0.04
1.876MetVal: 1.876 ± 0.05
0.183MetTrp: 0.183 ± 0.014
0.858MetTyr: 0.858 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
2.459AsnAla: 2.459 ± 0.051
0.298AsnCys: 0.298 ± 0.023
2.344AsnAsp: 2.344 ± 0.055
3.761AsnGlu: 3.761 ± 0.069
1.611AsnPhe: 1.611 ± 0.043
3.034AsnGly: 3.034 ± 0.066
1.291AsnHis: 1.291 ± 0.035
3.92AsnIle: 3.92 ± 0.072
3.568AsnLys: 3.568 ± 0.063
3.691AsnLeu: 3.691 ± 0.074
1.368AsnMet: 1.368 ± 0.04
2.122AsnAsn: 2.122 ± 0.066
2.083AsnPro: 2.083 ± 0.057
2.341AsnGln: 2.341 ± 0.054
2.07AsnArg: 2.07 ± 0.05
2.035AsnSer: 2.035 ± 0.055
2.302AsnThr: 2.302 ± 0.052
2.817AsnVal: 2.817 ± 0.05
0.537AsnTrp: 0.537 ± 0.027
1.673AsnTyr: 1.673 ± 0.05
0.0AsnXaa: 0.0 ± 0.0
Pro
2.04ProAla: 2.04 ± 0.055
0.2ProCys: 0.2 ± 0.016
1.923ProAsp: 1.923 ± 0.057
3.023ProGlu: 3.023 ± 0.077
1.954ProPhe: 1.954 ± 0.058
2.151ProGly: 2.151 ± 0.053
0.843ProHis: 0.843 ± 0.032
3.259ProIle: 3.259 ± 0.066
2.351ProLys: 2.351 ± 0.065
3.234ProLeu: 3.234 ± 0.061
0.822ProMet: 0.822 ± 0.034
1.813ProAsn: 1.813 ± 0.047
0.979ProPro: 0.979 ± 0.037
0.99ProGln: 0.99 ± 0.036
1.016ProArg: 1.016 ± 0.034
2.097ProSer: 2.097 ± 0.055
2.093ProThr: 2.093 ± 0.049
2.706ProVal: 2.706 ± 0.064
0.306ProTrp: 0.306 ± 0.021
1.405ProTyr: 1.405 ± 0.043
0.0ProXaa: 0.0 ± 0.0
Gln
2.742GlnAla: 2.742 ± 0.074
0.148GlnCys: 0.148 ± 0.012
1.912GlnAsp: 1.912 ± 0.052
3.013GlnGlu: 3.013 ± 0.065
1.683GlnPhe: 1.683 ± 0.05
2.0GlnGly: 2.0 ± 0.055
0.832GlnHis: 0.832 ± 0.035
3.073GlnIle: 3.073 ± 0.067
2.951GlnLys: 2.951 ± 0.058
4.305GlnLeu: 4.305 ± 0.077
1.33GlnMet: 1.33 ± 0.042
1.567GlnAsn: 1.567 ± 0.048
1.167GlnPro: 1.167 ± 0.04
1.906GlnGln: 1.906 ± 0.059
1.39GlnArg: 1.39 ± 0.043
2.136GlnSer: 2.136 ± 0.061
2.384GlnThr: 2.384 ± 0.052
2.454GlnVal: 2.454 ± 0.053
0.376GlnTrp: 0.376 ± 0.021
1.327GlnTyr: 1.327 ± 0.044
0.0GlnXaa: 0.0 ± 0.0
Arg
2.169ArgAla: 2.169 ± 0.06
0.202ArgCys: 0.202 ± 0.017
2.071ArgAsp: 2.071 ± 0.064
3.106ArgGlu: 3.106 ± 0.069
1.844ArgPhe: 1.844 ± 0.045
2.285ArgGly: 2.285 ± 0.052
0.77ArgHis: 0.77 ± 0.038
3.117ArgIle: 3.117 ± 0.064
3.525ArgLys: 3.525 ± 0.073
3.629ArgLeu: 3.629 ± 0.071
1.284ArgMet: 1.284 ± 0.037
2.02ArgAsn: 2.02 ± 0.05
1.124ArgPro: 1.124 ± 0.038
1.477ArgGln: 1.477 ± 0.04
1.761ArgArg: 1.761 ± 0.056
1.987ArgSer: 1.987 ± 0.053
2.057ArgThr: 2.057 ± 0.054
2.402ArgVal: 2.402 ± 0.058
0.347ArgTrp: 0.347 ± 0.019
1.493ArgTyr: 1.493 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
3.084SerAla: 3.084 ± 0.069
0.344SerCys: 0.344 ± 0.023
2.775SerAsp: 2.775 ± 0.058
3.711SerGlu: 3.711 ± 0.068
3.213SerPhe: 3.213 ± 0.062
4.271SerGly: 4.271 ± 0.084
1.18SerHis: 1.18 ± 0.035
5.337SerIle: 5.337 ± 0.088
3.882SerLys: 3.882 ± 0.077
5.656SerLeu: 5.656 ± 0.093
1.556SerMet: 1.556 ± 0.044
2.531SerAsn: 2.531 ± 0.061
1.937SerPro: 1.937 ± 0.054
1.685SerGln: 1.685 ± 0.053
2.04SerArg: 2.04 ± 0.05
3.37SerSer: 3.37 ± 0.07
2.952SerThr: 2.952 ± 0.059
3.821SerVal: 3.821 ± 0.087
0.525SerTrp: 0.525 ± 0.028
2.177SerTyr: 2.177 ± 0.048
0.0SerXaa: 0.0 ± 0.0
Thr
3.557ThrAla: 3.557 ± 0.074
0.361ThrCys: 0.361 ± 0.019
2.945ThrAsp: 2.945 ± 0.068
3.858ThrGlu: 3.858 ± 0.067
2.726ThrPhe: 2.726 ± 0.06
4.105ThrGly: 4.105 ± 0.079
1.134ThrHis: 1.134 ± 0.039
5.061ThrIle: 5.061 ± 0.08
3.895ThrLys: 3.895 ± 0.07
5.104ThrLeu: 5.104 ± 0.077
1.458ThrMet: 1.458 ± 0.044
2.874ThrAsn: 2.874 ± 0.061
2.27ThrPro: 2.27 ± 0.055
1.45ThrGln: 1.45 ± 0.049
1.81ThrArg: 1.81 ± 0.048
3.161ThrSer: 3.161 ± 0.053
3.081ThrThr: 3.081 ± 0.062
3.952ThrVal: 3.952 ± 0.078
0.505ThrTrp: 0.505 ± 0.025
2.188ThrTyr: 2.188 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
4.342ValAla: 4.342 ± 0.079
0.483ValCys: 0.483 ± 0.027
3.821ValAsp: 3.821 ± 0.08
4.881ValGlu: 4.881 ± 0.087
3.243ValPhe: 3.243 ± 0.082
4.472ValGly: 4.472 ± 0.085
1.42ValHis: 1.42 ± 0.044
5.996ValIle: 5.996 ± 0.081
4.604ValLys: 4.604 ± 0.08
6.421ValLeu: 6.421 ± 0.097
1.852ValMet: 1.852 ± 0.049
2.893ValAsn: 2.893 ± 0.058
2.493ValPro: 2.493 ± 0.064
2.303ValGln: 2.303 ± 0.054
2.408ValArg: 2.408 ± 0.056
4.093ValSer: 4.093 ± 0.075
4.026ValThr: 4.026 ± 0.074
4.613ValVal: 4.613 ± 0.085
0.547ValTrp: 0.547 ± 0.026
2.206ValTyr: 2.206 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.488TrpAla: 0.488 ± 0.024
0.076TrpCys: 0.076 ± 0.009
0.499TrpAsp: 0.499 ± 0.029
0.691TrpGlu: 0.691 ± 0.031
0.501TrpPhe: 0.501 ± 0.028
0.568TrpGly: 0.568 ± 0.03
0.205TrpHis: 0.205 ± 0.016
0.919TrpIle: 0.919 ± 0.035
0.763TrpLys: 0.763 ± 0.03
1.037TrpLeu: 1.037 ± 0.036
0.318TrpMet: 0.318 ± 0.021
0.482TrpAsn: 0.482 ± 0.027
0.228TrpPro: 0.228 ± 0.016
0.321TrpGln: 0.321 ± 0.019
0.351TrpArg: 0.351 ± 0.019
0.524TrpSer: 0.524 ± 0.026
0.457TrpThr: 0.457 ± 0.024
0.605TrpVal: 0.605 ± 0.028
0.146TrpTrp: 0.146 ± 0.012
0.334TrpTyr: 0.334 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.028TyrAla: 2.028 ± 0.051
0.263TyrCys: 0.263 ± 0.019
2.065TyrAsp: 2.065 ± 0.052
2.694TyrGlu: 2.694 ± 0.057
1.91TyrPhe: 1.91 ± 0.055
2.432TyrGly: 2.432 ± 0.064
0.976TyrHis: 0.976 ± 0.035
2.9TyrIle: 2.9 ± 0.071
2.197TyrLys: 2.197 ± 0.06
3.474TyrLeu: 3.474 ± 0.066
0.935TyrMet: 0.935 ± 0.036
1.382TyrAsn: 1.382 ± 0.046
1.464TyrPro: 1.464 ± 0.049
1.651TyrGln: 1.651 ± 0.048
1.697TyrArg: 1.697 ± 0.065
1.874TyrSer: 1.874 ± 0.057
1.943TyrThr: 1.943 ± 0.047
2.313TyrVal: 2.313 ± 0.052
0.374TyrTrp: 0.374 ± 0.025
1.429TyrTyr: 1.429 ± 0.048
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2897 proteins (845080 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski