Human papillomavirus 141
Average proteome isoelectric point is 6.16
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|I3P6N3|I3P6N3_9PAPI Replication protein E1 OS=Human papillomavirus 141 OX=1070414 GN=E1 PE=3 SV=1
MM1 pKa = 7.1 MGEE4 pKa = 4.44 KK5 pKa = 9.07 PTMRR9 pKa = 11.84 DD10 pKa = 2.43 IDD12 pKa = 4.09 LEE14 pKa = 4.29 EE15 pKa = 4.08 TLEE18 pKa = 4.0 NLVMPSSLLCEE29 pKa = 4.44 EE30 pKa = 4.74 SLSPDD35 pKa = 3.34 DD36 pKa = 4.0 TPEE39 pKa = 4.08 EE40 pKa = 4.39 EE41 pKa = 4.46 SLSPYY46 pKa = 9.32 WVDD49 pKa = 4.87 SRR51 pKa = 11.84 CDD53 pKa = 3.19 SCKK56 pKa = 10.72 NPVRR60 pKa = 11.84 LCVVATSGAIHH71 pKa = 7.14 LLEE74 pKa = 3.76 QLLFNDD80 pKa = 4.52 LCIVCPVCSRR90 pKa = 11.84 TLVRR94 pKa = 11.84 HH95 pKa = 5.63 GRR97 pKa = 11.84 HH98 pKa = 5.27
Molecular weight: 11.02 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 4.377
IPC2_protein 4.584
IPC_protein 4.457
Toseland 4.317
ProMoST 4.533
Dawson 4.406
Bjellqvist 4.558
Wikipedia 4.279
Rodwell 4.304
Grimsley 4.228
Solomon 4.406
Lehninger 4.355
Nozaki 4.52
DTASelect 4.66
Thurlkill 4.329
EMBOSS 4.304
Sillero 4.584
Patrickios 2.969
IPC_peptide 4.418
IPC2_peptide 4.571
IPC2.peptide.svr19 4.509
Protein with the highest isoelectric point:
>tr|I3P6N5|I3P6N5_9PAPI Uncharacterized protein OS=Human papillomavirus 141 OX=1070414 GN=E4 PE=4 SV=1
MM1 pKa = 6.88 NQEE4 pKa = 4.39 DD5 pKa = 3.85 LRR7 pKa = 11.84 KK8 pKa = 9.71 RR9 pKa = 11.84 LDD11 pKa = 3.69 VIQTQLMTLYY21 pKa = 10.41 EE22 pKa = 4.7 SNPKK26 pKa = 10.05 DD27 pKa = 3.56 LQSQITHH34 pKa = 5.8 YY35 pKa = 10.96 KK36 pKa = 10.24 LLRR39 pKa = 11.84 KK40 pKa = 9.31 EE41 pKa = 4.3 CAIQYY46 pKa = 6.75 YY47 pKa = 9.77 ARR49 pKa = 11.84 KK50 pKa = 9.56 EE51 pKa = 4.33 GYY53 pKa = 9.79 QNLGLQHH60 pKa = 7.13 LPTTRR65 pKa = 11.84 ISEE68 pKa = 4.44 HH69 pKa = 6.16 NSKK72 pKa = 10.24 QAIKK76 pKa = 7.91 MTLMLEE82 pKa = 4.27 SLAKK86 pKa = 9.85 SQYY89 pKa = 9.15 ATEE92 pKa = 4.03 EE93 pKa = 4.09 WTLHH97 pKa = 5.67 DD98 pKa = 3.59 TSADD102 pKa = 3.54 RR103 pKa = 11.84 FLSPPRR109 pKa = 11.84 NCFKK113 pKa = 10.94 KK114 pKa = 10.35 NSFEE118 pKa = 4.29 VEE120 pKa = 3.72 VWFDD124 pKa = 3.98 NNPKK128 pKa = 10.26 NAFPYY133 pKa = 10.07 ICWEE137 pKa = 3.99 WIYY140 pKa = 11.09 YY141 pKa = 9.18 QDD143 pKa = 5.77 EE144 pKa = 4.34 SDD146 pKa = 3.43 TWHH149 pKa = 6.76 KK150 pKa = 11.21 VPGKK154 pKa = 10.14 VDD156 pKa = 3.61 YY157 pKa = 11.26 NGLYY161 pKa = 9.88 YY162 pKa = 10.62 VEE164 pKa = 4.54 IDD166 pKa = 3.22 GTAVYY171 pKa = 10.08 FLLFHH176 pKa = 7.19 KK177 pKa = 10.78 DD178 pKa = 2.6 AGRR181 pKa = 11.84 YY182 pKa = 8.3 GNSGEE187 pKa = 3.85 WTVNYY192 pKa = 10.03 KK193 pKa = 10.32 NEE195 pKa = 4.26 QILPPSVGSSTRR207 pKa = 11.84 RR208 pKa = 11.84 SVSEE212 pKa = 4.14 SQDD215 pKa = 3.15 PTINTPSNAEE225 pKa = 3.87 TEE227 pKa = 4.43 TQNRR231 pKa = 11.84 RR232 pKa = 11.84 RR233 pKa = 11.84 EE234 pKa = 4.24 VQQEE238 pKa = 4.35 TPGPSSTTRR247 pKa = 11.84 SPKK250 pKa = 8.97 RR251 pKa = 11.84 GQRR254 pKa = 11.84 RR255 pKa = 11.84 RR256 pKa = 11.84 RR257 pKa = 11.84 GGEE260 pKa = 3.91 GEE262 pKa = 3.98 QTSGKK267 pKa = 9.37 RR268 pKa = 11.84 RR269 pKa = 11.84 RR270 pKa = 11.84 RR271 pKa = 11.84 SEE273 pKa = 3.64 GRR275 pKa = 11.84 GGSDD279 pKa = 3.15 SITPEE284 pKa = 3.99 EE285 pKa = 4.12 VGKK288 pKa = 8.31 SHH290 pKa = 7.38 RR291 pKa = 11.84 SVPATGLSRR300 pKa = 11.84 VDD302 pKa = 3.34 RR303 pKa = 11.84 LKK305 pKa = 11.26 AEE307 pKa = 4.54 AKK309 pKa = 9.81 DD310 pKa = 3.57 PPIIIVKK317 pKa = 10.3 GCANKK322 pKa = 10.1 LKK324 pKa = 10.33 CWRR327 pKa = 11.84 FRR329 pKa = 11.84 CNQKK333 pKa = 10.12 CPRR336 pKa = 11.84 PYY338 pKa = 11.0 NYY340 pKa = 7.16 MTSVFKK346 pKa = 10.61 WITNDD351 pKa = 2.89 VKK353 pKa = 11.06 LADD356 pKa = 3.84 SRR358 pKa = 11.84 VLVAFADD365 pKa = 3.49 NTQRR369 pKa = 11.84 SRR371 pKa = 11.84 FIANVSFPKK380 pKa = 9.79 DD381 pKa = 3.07 TSYY384 pKa = 11.57 CFGSLEE390 pKa = 4.18 CLL392 pKa = 3.55
Molecular weight: 45.26 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 8.688
IPC2_protein 8.58
IPC_protein 8.478
Toseland 8.99
ProMoST 8.96
Dawson 9.37
Bjellqvist 9.268
Wikipedia 9.545
Rodwell 9.516
Grimsley 9.399
Solomon 9.428
Lehninger 9.385
Nozaki 9.37
DTASelect 9.151
Thurlkill 9.253
EMBOSS 9.502
Sillero 9.428
Patrickios 4.622
IPC_peptide 9.414
IPC2_peptide 8.068
IPC2.peptide.svr19 7.712
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
7
0
7
2408
98
604
344.0
39.17
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.191 ± 0.398
2.575 ± 0.903
6.894 ± 0.478
6.063 ± 0.51
4.693 ± 0.448
4.776 ± 0.847
1.91 ± 0.145
5.648 ± 0.564
5.731 ± 0.836
9.302 ± 1.043
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
1.703 ± 0.348
4.817 ± 0.279
6.271 ± 0.994
4.734 ± 0.465
5.689 ± 0.752
7.434 ± 0.629
6.312 ± 0.743
5.399 ± 0.35
1.287 ± 0.232
3.571 ± 0.567
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here