Human papillomavirus 141

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 11

Average proteome isoelectric point is 6.16

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|I3P6N3|I3P6N3_9PAPI Replication protein E1 OS=Human papillomavirus 141 OX=1070414 GN=E1 PE=3 SV=1
MM1 pKa = 7.1MGEE4 pKa = 4.44KK5 pKa = 9.07PTMRR9 pKa = 11.84DD10 pKa = 2.43IDD12 pKa = 4.09LEE14 pKa = 4.29EE15 pKa = 4.08TLEE18 pKa = 4.0NLVMPSSLLCEE29 pKa = 4.44EE30 pKa = 4.74SLSPDD35 pKa = 3.34DD36 pKa = 4.0TPEE39 pKa = 4.08EE40 pKa = 4.39EE41 pKa = 4.46SLSPYY46 pKa = 9.32WVDD49 pKa = 4.87SRR51 pKa = 11.84CDD53 pKa = 3.19SCKK56 pKa = 10.72NPVRR60 pKa = 11.84LCVVATSGAIHH71 pKa = 7.14LLEE74 pKa = 3.76QLLFNDD80 pKa = 4.52LCIVCPVCSRR90 pKa = 11.84TLVRR94 pKa = 11.84HH95 pKa = 5.63GRR97 pKa = 11.84HH98 pKa = 5.27

Molecular weight:
11.02 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|I3P6N5|I3P6N5_9PAPI Uncharacterized protein OS=Human papillomavirus 141 OX=1070414 GN=E4 PE=4 SV=1
MM1 pKa = 6.88NQEE4 pKa = 4.39DD5 pKa = 3.85LRR7 pKa = 11.84KK8 pKa = 9.71RR9 pKa = 11.84LDD11 pKa = 3.69VIQTQLMTLYY21 pKa = 10.41EE22 pKa = 4.7SNPKK26 pKa = 10.05DD27 pKa = 3.56LQSQITHH34 pKa = 5.8YY35 pKa = 10.96KK36 pKa = 10.24LLRR39 pKa = 11.84KK40 pKa = 9.31EE41 pKa = 4.3CAIQYY46 pKa = 6.75YY47 pKa = 9.77ARR49 pKa = 11.84KK50 pKa = 9.56EE51 pKa = 4.33GYY53 pKa = 9.79QNLGLQHH60 pKa = 7.13LPTTRR65 pKa = 11.84ISEE68 pKa = 4.44HH69 pKa = 6.16NSKK72 pKa = 10.24QAIKK76 pKa = 7.91MTLMLEE82 pKa = 4.27SLAKK86 pKa = 9.85SQYY89 pKa = 9.15ATEE92 pKa = 4.03EE93 pKa = 4.09WTLHH97 pKa = 5.67DD98 pKa = 3.59TSADD102 pKa = 3.54RR103 pKa = 11.84FLSPPRR109 pKa = 11.84NCFKK113 pKa = 10.94KK114 pKa = 10.35NSFEE118 pKa = 4.29VEE120 pKa = 3.72VWFDD124 pKa = 3.98NNPKK128 pKa = 10.26NAFPYY133 pKa = 10.07ICWEE137 pKa = 3.99WIYY140 pKa = 11.09YY141 pKa = 9.18QDD143 pKa = 5.77EE144 pKa = 4.34SDD146 pKa = 3.43TWHH149 pKa = 6.76KK150 pKa = 11.21VPGKK154 pKa = 10.14VDD156 pKa = 3.61YY157 pKa = 11.26NGLYY161 pKa = 9.88YY162 pKa = 10.62VEE164 pKa = 4.54IDD166 pKa = 3.22GTAVYY171 pKa = 10.08FLLFHH176 pKa = 7.19KK177 pKa = 10.78DD178 pKa = 2.6AGRR181 pKa = 11.84YY182 pKa = 8.3GNSGEE187 pKa = 3.85WTVNYY192 pKa = 10.03KK193 pKa = 10.32NEE195 pKa = 4.26QILPPSVGSSTRR207 pKa = 11.84RR208 pKa = 11.84SVSEE212 pKa = 4.14SQDD215 pKa = 3.15PTINTPSNAEE225 pKa = 3.87TEE227 pKa = 4.43TQNRR231 pKa = 11.84RR232 pKa = 11.84RR233 pKa = 11.84EE234 pKa = 4.24VQQEE238 pKa = 4.35TPGPSSTTRR247 pKa = 11.84SPKK250 pKa = 8.97RR251 pKa = 11.84GQRR254 pKa = 11.84RR255 pKa = 11.84RR256 pKa = 11.84RR257 pKa = 11.84GGEE260 pKa = 3.91GEE262 pKa = 3.98QTSGKK267 pKa = 9.37RR268 pKa = 11.84RR269 pKa = 11.84RR270 pKa = 11.84RR271 pKa = 11.84SEE273 pKa = 3.64GRR275 pKa = 11.84GGSDD279 pKa = 3.15SITPEE284 pKa = 3.99EE285 pKa = 4.12VGKK288 pKa = 8.31SHH290 pKa = 7.38RR291 pKa = 11.84SVPATGLSRR300 pKa = 11.84VDD302 pKa = 3.34RR303 pKa = 11.84LKK305 pKa = 11.26AEE307 pKa = 4.54AKK309 pKa = 9.81DD310 pKa = 3.57PPIIIVKK317 pKa = 10.3GCANKK322 pKa = 10.1LKK324 pKa = 10.33CWRR327 pKa = 11.84FRR329 pKa = 11.84CNQKK333 pKa = 10.12CPRR336 pKa = 11.84PYY338 pKa = 11.0NYY340 pKa = 7.16MTSVFKK346 pKa = 10.61WITNDD351 pKa = 2.89VKK353 pKa = 11.06LADD356 pKa = 3.84SRR358 pKa = 11.84VLVAFADD365 pKa = 3.49NTQRR369 pKa = 11.84SRR371 pKa = 11.84FIANVSFPKK380 pKa = 9.79DD381 pKa = 3.07TSYY384 pKa = 11.57CFGSLEE390 pKa = 4.18CLL392 pKa = 3.55

Molecular weight:
45.26 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2408

98

604

344.0

39.17

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.191 ± 0.398

2.575 ± 0.903

6.894 ± 0.478

6.063 ± 0.51

4.693 ± 0.448

4.776 ± 0.847

1.91 ± 0.145

5.648 ± 0.564

5.731 ± 0.836

9.302 ± 1.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.703 ± 0.348

4.817 ± 0.279

6.271 ± 0.994

4.734 ± 0.465

5.689 ± 0.752

7.434 ± 0.629

6.312 ± 0.743

5.399 ± 0.35

1.287 ± 0.232

3.571 ± 0.567

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski