Amino acid dipepetide frequency for Lampropedia cohaerens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.646AlaAla: 17.646 ± 0.234	1.371AlaCys: 1.371 ± 0.047	6.315AlaAsp: 6.315 ± 0.094	6.644AlaGlu: 6.644 ± 0.12	4.031AlaPhe: 4.031 ± 0.067	9.972AlaGly: 9.972 ± 0.128	2.962AlaHis: 2.962 ± 0.07	6.03AlaIle: 6.03 ± 0.092	3.214AlaLys: 3.214 ± 0.065	15.736AlaLeu: 15.736 ± 0.204	3.657AlaMet: 3.657 ± 0.076	2.808AlaAsn: 2.808 ± 0.071	6.156AlaPro: 6.156 ± 0.091	7.576AlaGln: 7.576 ± 0.118	9.152AlaArg: 9.152 ± 0.13	6.744AlaSer: 6.744 ± 0.097	6.136AlaThr: 6.136 ± 0.099	8.843AlaVal: 8.843 ± 0.125	1.951AlaTrp: 1.951 ± 0.06	2.603AlaTyr: 2.603 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	1.178CysAla: 1.178 ± 0.043	0.12CysCys: 0.12 ± 0.013	0.467CysAsp: 0.467 ± 0.024	0.466CysGlu: 0.466 ± 0.024	0.303CysPhe: 0.303 ± 0.019	0.924CysGly: 0.924 ± 0.039	0.265CysHis: 0.265 ± 0.02	0.461CysIle: 0.461 ± 0.023	0.195CysLys: 0.195 ± 0.016	0.849CysLeu: 0.849 ± 0.035	0.23CysMet: 0.23 ± 0.019	0.246CysAsn: 0.246 ± 0.017	0.452CysPro: 0.452 ± 0.025	0.345CysGln: 0.345 ± 0.02	0.569CysArg: 0.569 ± 0.025	0.47CysSer: 0.47 ± 0.026	0.55CysThr: 0.55 ± 0.029	0.748CysVal: 0.748 ± 0.029	0.139CysTrp: 0.139 ± 0.013	0.198CysTyr: 0.198 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.626AspAla: 7.626 ± 0.093	0.493AspCys: 0.493 ± 0.022	2.65AspAsp: 2.65 ± 0.072	2.904AspGlu: 2.904 ± 0.066	1.902AspPhe: 1.902 ± 0.052	4.59AspGly: 4.59 ± 0.101	1.024AspHis: 1.024 ± 0.04	2.445AspIle: 2.445 ± 0.061	1.48AspLys: 1.48 ± 0.05	4.977AspLeu: 4.977 ± 0.09	1.204AspMet: 1.204 ± 0.044	1.198AspAsn: 1.198 ± 0.043	2.719AspPro: 2.719 ± 0.059	1.532AspGln: 1.532 ± 0.046	3.011AspArg: 3.011 ± 0.067	2.204AspSer: 2.204 ± 0.071	2.407AspThr: 2.407 ± 0.066	4.151AspVal: 4.151 ± 0.074	1.03AspTrp: 1.03 ± 0.033	1.492AspTyr: 1.492 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.564GluAla: 6.564 ± 0.101	0.35GluCys: 0.35 ± 0.023	2.462GluAsp: 2.462 ± 0.059	2.615GluGlu: 2.615 ± 0.07	1.635GluPhe: 1.635 ± 0.051	3.691GluGly: 3.691 ± 0.078	1.38GluHis: 1.38 ± 0.04	2.666GluIle: 2.666 ± 0.058	1.801GluLys: 1.801 ± 0.056	5.533GluLeu: 5.533 ± 0.093	1.247GluMet: 1.247 ± 0.04	1.34GluAsn: 1.34 ± 0.04	2.51GluPro: 2.51 ± 0.055	3.273GluGln: 3.273 ± 0.069	4.563GluArg: 4.563 ± 0.092	2.313GluSer: 2.313 ± 0.054	2.472GluThr: 2.472 ± 0.058	3.952GluVal: 3.952 ± 0.072	0.703GluTrp: 0.703 ± 0.03	1.11GluTyr: 1.11 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	4.246PheAla: 4.246 ± 0.08	0.37PheCys: 0.37 ± 0.023	2.305PheAsp: 2.305 ± 0.05	1.978PheGlu: 1.978 ± 0.048	1.309PhePhe: 1.309 ± 0.039	3.155PheGly: 3.155 ± 0.066	0.712PheHis: 0.712 ± 0.028	1.596PheIle: 1.596 ± 0.047	0.985PheLys: 0.985 ± 0.031	2.99PheLeu: 2.99 ± 0.06	0.779PheMet: 0.779 ± 0.034	1.098PheAsn: 1.098 ± 0.036	1.442PhePro: 1.442 ± 0.044	1.112PheGln: 1.112 ± 0.035	1.775PheArg: 1.775 ± 0.051	2.092PheSer: 2.092 ± 0.046	1.869PheThr: 1.869 ± 0.052	2.596PheVal: 2.596 ± 0.063	0.563PheTrp: 0.563 ± 0.028	0.815PheTyr: 0.815 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	8.722GlyAla: 8.722 ± 0.122	0.826GlyCys: 0.826 ± 0.035	3.89GlyAsp: 3.89 ± 0.086	4.352GlyGlu: 4.352 ± 0.081	3.103GlyPhe: 3.103 ± 0.062	6.179GlyGly: 6.179 ± 0.113	1.971GlyHis: 1.971 ± 0.059	4.176GlyIle: 4.176 ± 0.082	3.086GlyLys: 3.086 ± 0.066	8.501GlyLeu: 8.501 ± 0.116	2.36GlyMet: 2.36 ± 0.066	2.151GlyAsn: 2.151 ± 0.074	2.869GlyPro: 2.869 ± 0.061	3.984GlyGln: 3.984 ± 0.082	5.114GlyArg: 5.114 ± 0.089	4.32GlySer: 4.32 ± 0.077	4.145GlyThr: 4.145 ± 0.087	6.264GlyVal: 6.264 ± 0.097	1.407GlyTrp: 1.407 ± 0.046	2.291GlyTyr: 2.291 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	3.395HisAla: 3.395 ± 0.074	0.288HisCys: 0.288 ± 0.018	1.268HisAsp: 1.268 ± 0.04	1.075HisGlu: 1.075 ± 0.042	0.93HisPhe: 0.93 ± 0.032	2.211HisGly: 2.211 ± 0.055	0.675HisHis: 0.675 ± 0.026	1.114HisIle: 1.114 ± 0.035	0.539HisLys: 0.539 ± 0.026	2.318HisLeu: 2.318 ± 0.062	0.59HisMet: 0.59 ± 0.024	0.567HisAsn: 0.567 ± 0.026	1.473HisPro: 1.473 ± 0.051	0.863HisGln: 0.863 ± 0.032	1.496HisArg: 1.496 ± 0.043	1.137HisSer: 1.137 ± 0.037	1.177HisThr: 1.177 ± 0.038	1.736HisVal: 1.736 ± 0.047	0.496HisTrp: 0.496 ± 0.025	0.702HisTyr: 0.702 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.847IleAla: 6.847 ± 0.104	0.417IleCys: 0.417 ± 0.026	3.061IleAsp: 3.061 ± 0.057	3.25IleGlu: 3.25 ± 0.061	1.394IlePhe: 1.394 ± 0.046	4.361IleGly: 4.361 ± 0.081	0.957IleHis: 0.957 ± 0.037	1.877IleIle: 1.877 ± 0.054	1.387IleLys: 1.387 ± 0.041	3.793IleLeu: 3.793 ± 0.073	0.855IleMet: 0.855 ± 0.035	1.423IleAsn: 1.423 ± 0.047	2.107IlePro: 2.107 ± 0.051	1.475IleGln: 1.475 ± 0.038	2.731IleArg: 2.731 ± 0.049	2.365IleSer: 2.365 ± 0.058	2.689IleThr: 2.689 ± 0.067	3.714IleVal: 3.714 ± 0.069	0.593IleTrp: 0.593 ± 0.027	1.069IleTyr: 1.069 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.588LysAla: 3.588 ± 0.067	0.142LysCys: 0.142 ± 0.014	1.343LysAsp: 1.343 ± 0.043	1.408LysGlu: 1.408 ± 0.05	0.739LysPhe: 0.739 ± 0.034	2.193LysGly: 2.193 ± 0.059	0.609LysHis: 0.609 ± 0.026	1.256LysIle: 1.256 ± 0.041	1.12LysLys: 1.12 ± 0.046	3.069LysLeu: 3.069 ± 0.064	0.657LysMet: 0.657 ± 0.028	0.838LysAsn: 0.838 ± 0.03	1.805LysPro: 1.805 ± 0.053	1.229LysGln: 1.229 ± 0.046	1.984LysArg: 1.984 ± 0.052	1.526LysSer: 1.526 ± 0.045	1.616LysThr: 1.616 ± 0.049	2.382LysVal: 2.382 ± 0.062	0.321LysTrp: 0.321 ± 0.021	0.598LysTyr: 0.598 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	15.131LeuAla: 15.131 ± 0.204	1.045LeuCys: 1.045 ± 0.037	5.658LeuAsp: 5.658 ± 0.087	5.435LeuGlu: 5.435 ± 0.094	3.428LeuPhe: 3.428 ± 0.072	8.519LeuGly: 8.519 ± 0.117	2.755LeuHis: 2.755 ± 0.067	4.435LeuIle: 4.435 ± 0.074	3.009LeuLys: 3.009 ± 0.071	12.249LeuLeu: 12.249 ± 0.213	2.455LeuMet: 2.455 ± 0.064	2.546LeuAsn: 2.546 ± 0.06	6.261LeuPro: 6.261 ± 0.099	6.141LeuGln: 6.141 ± 0.109	8.338LeuArg: 8.338 ± 0.116	5.466LeuSer: 5.466 ± 0.082	5.438LeuThr: 5.438 ± 0.085	7.911LeuVal: 7.911 ± 0.124	1.399LeuTrp: 1.399 ± 0.046	2.2LeuTyr: 2.2 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	3.244MetAla: 3.244 ± 0.067	0.16MetCys: 0.16 ± 0.014	1.098MetAsp: 1.098 ± 0.038	1.08MetGlu: 1.08 ± 0.036	0.66MetPhe: 0.66 ± 0.031	1.893MetGly: 1.893 ± 0.054	0.617MetHis: 0.617 ± 0.026	0.938MetIle: 0.938 ± 0.037	0.692MetLys: 0.692 ± 0.032	2.925MetLeu: 2.925 ± 0.065	0.532MetMet: 0.532 ± 0.027	0.716MetAsn: 0.716 ± 0.031	1.497MetPro: 1.497 ± 0.045	1.36MetGln: 1.36 ± 0.039	1.855MetArg: 1.855 ± 0.05	1.324MetSer: 1.324 ± 0.045	1.494MetThr: 1.494 ± 0.054	1.794MetVal: 1.794 ± 0.055	0.226MetTrp: 0.226 ± 0.016	0.363MetTyr: 0.363 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.237AsnAla: 3.237 ± 0.079	0.225AsnCys: 0.225 ± 0.017	1.2AsnAsp: 1.2 ± 0.051	1.109AsnGlu: 1.109 ± 0.035	0.874AsnPhe: 0.874 ± 0.035	2.121AsnGly: 2.121 ± 0.061	0.57AsnHis: 0.57 ± 0.029	1.301AsnIle: 1.301 ± 0.049	0.706AsnLys: 0.706 ± 0.03	2.658AsnLeu: 2.658 ± 0.062	0.59AsnMet: 0.59 ± 0.029	0.68AsnAsn: 0.68 ± 0.032	1.86AsnPro: 1.86 ± 0.051	0.886AsnGln: 0.886 ± 0.032	1.626AsnArg: 1.626 ± 0.045	1.107AsnSer: 1.107 ± 0.04	1.37AsnThr: 1.37 ± 0.047	1.961AsnVal: 1.961 ± 0.048	0.403AsnTrp: 0.403 ± 0.019	0.658AsnTyr: 0.658 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.073ProAla: 7.073 ± 0.105	0.368ProCys: 0.368 ± 0.021	3.087ProAsp: 3.087 ± 0.06	3.123ProGlu: 3.123 ± 0.066	1.801ProPhe: 1.801 ± 0.041	4.191ProGly: 4.191 ± 0.069	1.251ProHis: 1.251 ± 0.038	2.046ProIle: 2.046 ± 0.051	1.25ProLys: 1.25 ± 0.037	5.419ProLeu: 5.419 ± 0.092	1.26ProMet: 1.26 ± 0.042	1.138ProAsn: 1.138 ± 0.034	2.588ProPro: 2.588 ± 0.073	2.798ProGln: 2.798 ± 0.06	2.958ProArg: 2.958 ± 0.065	2.694ProSer: 2.694 ± 0.069	2.483ProThr: 2.483 ± 0.056	4.224ProVal: 4.224 ± 0.07	0.746ProTrp: 0.746 ± 0.033	1.193ProTyr: 1.193 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	7.358GlnAla: 7.358 ± 0.134	0.361GlnCys: 0.361 ± 0.019	2.033GlnAsp: 2.033 ± 0.055	2.305GlnGlu: 2.305 ± 0.06	1.41GlnPhe: 1.41 ± 0.039	3.631GlnGly: 3.631 ± 0.063	1.228GlnHis: 1.228 ± 0.034	2.041GlnIle: 2.041 ± 0.048	1.07GlnLys: 1.07 ± 0.04	5.555GlnLeu: 5.555 ± 0.094	1.122GlnMet: 1.122 ± 0.038	0.888GlnAsn: 0.888 ± 0.037	2.864GlnPro: 2.864 ± 0.062	3.229GlnGln: 3.229 ± 0.089	4.266GlnArg: 4.266 ± 0.085	2.373GlnSer: 2.373 ± 0.054	2.312GlnThr: 2.312 ± 0.06	3.74GlnVal: 3.74 ± 0.066	1.024GlnTrp: 1.024 ± 0.039	0.977GlnTyr: 0.977 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	7.931ArgAla: 7.931 ± 0.107	0.567ArgCys: 0.567 ± 0.026	3.447ArgAsp: 3.447 ± 0.07	4.089ArgGlu: 4.089 ± 0.076	2.528ArgPhe: 2.528 ± 0.062	4.425ArgGly: 4.425 ± 0.081	1.96ArgHis: 1.96 ± 0.051	3.807ArgIle: 3.807 ± 0.067	2.196ArgLys: 2.196 ± 0.047	7.784ArgLeu: 7.784 ± 0.11	1.958ArgMet: 1.958 ± 0.045	2.013ArgAsn: 2.013 ± 0.049	3.12ArgPro: 3.12 ± 0.073	3.804ArgGln: 3.804 ± 0.078	5.132ArgArg: 5.132 ± 0.099	3.451ArgSer: 3.451 ± 0.07	3.327ArgThr: 3.327 ± 0.057	4.696ArgVal: 4.696 ± 0.085	1.197ArgTrp: 1.197 ± 0.041	2.026ArgTyr: 2.026 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.348SerAla: 6.348 ± 0.084	0.451SerCys: 0.451 ± 0.025	2.616SerAsp: 2.616 ± 0.064	2.475SerGlu: 2.475 ± 0.052	1.837SerPhe: 1.837 ± 0.042	4.869SerGly: 4.869 ± 0.102	1.242SerHis: 1.242 ± 0.041	2.363SerIle: 2.363 ± 0.051	1.35SerLys: 1.35 ± 0.041	5.275SerLeu: 5.275 ± 0.086	1.238SerMet: 1.238 ± 0.036	1.339SerAsn: 1.339 ± 0.041	2.617SerPro: 2.617 ± 0.06	2.085SerGln: 2.085 ± 0.046	3.287SerArg: 3.287 ± 0.068	2.758SerSer: 2.758 ± 0.07	2.663SerThr: 2.663 ± 0.059	3.688SerVal: 3.688 ± 0.071	0.726SerTrp: 0.726 ± 0.029	1.269SerTyr: 1.269 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.872ThrAla: 5.872 ± 0.101	0.394ThrCys: 0.394 ± 0.025	2.431ThrAsp: 2.431 ± 0.061	2.264ThrGlu: 2.264 ± 0.053	1.649ThrPhe: 1.649 ± 0.045	4.504ThrGly: 4.504 ± 0.087	1.18ThrHis: 1.18 ± 0.035	2.531ThrIle: 2.531 ± 0.074	1.193ThrLys: 1.193 ± 0.037	6.357ThrLeu: 6.357 ± 0.097	1.107ThrMet: 1.107 ± 0.036	1.246ThrAsn: 1.246 ± 0.037	3.46ThrPro: 3.46 ± 0.069	2.201ThrGln: 2.201 ± 0.049	3.246ThrArg: 3.246 ± 0.064	2.518ThrSer: 2.518 ± 0.053	2.675ThrThr: 2.675 ± 0.062	4.225ThrVal: 4.225 ± 0.086	0.647ThrTrp: 0.647 ± 0.027	1.137ThrTyr: 1.137 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	9.426ValAla: 9.426 ± 0.13	0.781ValCys: 0.781 ± 0.035	3.855ValAsp: 3.855 ± 0.081	3.807ValGlu: 3.807 ± 0.075	2.771ValPhe: 2.771 ± 0.069	5.314ValGly: 5.314 ± 0.096	1.76ValHis: 1.76 ± 0.047	3.638ValIle: 3.638 ± 0.073	2.161ValLys: 2.161 ± 0.056	8.841ValLeu: 8.841 ± 0.123	1.764ValMet: 1.764 ± 0.045	1.921ValAsn: 1.921 ± 0.05	3.99ValPro: 3.99 ± 0.067	3.68ValGln: 3.68 ± 0.073	5.283ValArg: 5.283 ± 0.096	3.679ValSer: 3.679 ± 0.072	4.149ValThr: 4.149 ± 0.095	6.212ValVal: 6.212 ± 0.103	0.979ValTrp: 0.979 ± 0.038	1.582ValTyr: 1.582 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.264TrpAla: 1.264 ± 0.045	0.184TrpCys: 0.184 ± 0.016	0.603TrpAsp: 0.603 ± 0.028	0.572TrpGlu: 0.572 ± 0.024	0.539TrpPhe: 0.539 ± 0.028	0.929TrpGly: 0.929 ± 0.036	0.446TrpHis: 0.446 ± 0.023	0.686TrpIle: 0.686 ± 0.029	0.414TrpLys: 0.414 ± 0.022	2.469TrpLeu: 2.469 ± 0.071	0.417TrpMet: 0.417 ± 0.022	0.393TrpAsn: 0.393 ± 0.02	0.758TrpPro: 0.758 ± 0.029	1.247TrpGln: 1.247 ± 0.05	1.323TrpArg: 1.323 ± 0.044	0.713TrpSer: 0.713 ± 0.033	0.633TrpThr: 0.633 ± 0.025	1.036TrpVal: 1.036 ± 0.04	0.29TrpTrp: 0.29 ± 0.021	0.303TrpTyr: 0.303 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.848TyrAla: 2.848 ± 0.063	0.259TyrCys: 0.259 ± 0.018	1.254TyrAsp: 1.254 ± 0.047	1.228TyrGlu: 1.228 ± 0.041	0.945TyrPhe: 0.945 ± 0.03	2.039TyrGly: 2.039 ± 0.057	0.487TyrHis: 0.487 ± 0.026	0.957TyrIle: 0.957 ± 0.032	0.574TyrLys: 0.574 ± 0.027	2.518TyrLeu: 2.518 ± 0.057	0.45TyrMet: 0.45 ± 0.025	0.592TyrAsn: 0.592 ± 0.029	1.144TyrPro: 1.144 ± 0.041	0.97TyrGln: 0.97 ± 0.038	1.747TyrArg: 1.747 ± 0.047	1.241TyrSer: 1.241 ± 0.039	1.231TyrThr: 1.231 ± 0.043	1.72TyrVal: 1.72 ± 0.042	0.379TyrTrp: 0.379 ± 0.02	0.619TyrTyr: 0.619 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2593 proteins (849440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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