Caprine arthritis encephalitis virus (CAEV)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus

Average proteome isoelectric point is 8.49

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|C9DI74|C9DI74_CAEV Rev protein OS=Caprine arthritis encephalitis virus OX=11660 GN=rev PE=4 SV=1
MM1 pKa = 7.93DD2 pKa = 4.9KK3 pKa = 10.93KK4 pKa = 10.68DD5 pKa = 3.54GKK7 pKa = 9.07RR8 pKa = 11.84TRR10 pKa = 11.84TEE12 pKa = 3.84EE13 pKa = 4.0PPLRR17 pKa = 11.84EE18 pKa = 3.45VWRR21 pKa = 11.84QVMSEE26 pKa = 3.87YY27 pKa = 10.39RR28 pKa = 11.84SRR30 pKa = 11.84YY31 pKa = 7.31PGKK34 pKa = 9.53ATRR37 pKa = 11.84QGLWGMRR44 pKa = 11.84LVVIIGIMGQLSSGAEE60 pKa = 4.22YY61 pKa = 8.76ITLVSDD67 pKa = 4.24PYY69 pKa = 10.67GFKK72 pKa = 10.64PIRR75 pKa = 11.84DD76 pKa = 3.74VTNVPVTCVTKK87 pKa = 10.99NFTQWGCQPEE97 pKa = 4.79GAYY100 pKa = 9.72PDD102 pKa = 3.86PEE104 pKa = 3.94KK105 pKa = 10.55EE106 pKa = 3.81YY107 pKa = 11.08RR108 pKa = 11.84NISRR112 pKa = 11.84EE113 pKa = 3.87ILEE116 pKa = 4.08EE117 pKa = 4.37VYY119 pKa = 11.17NKK121 pKa = 7.9TWPWRR126 pKa = 11.84TYY128 pKa = 10.03HH129 pKa = 5.67WPLWQMEE136 pKa = 3.93NMRR139 pKa = 11.84DD140 pKa = 3.19WAEE143 pKa = 4.09QNLQNNKK150 pKa = 7.83TRR152 pKa = 11.84PEE154 pKa = 3.94IEE156 pKa = 4.0KK157 pKa = 10.72LLAGEE162 pKa = 3.73IRR164 pKa = 11.84GRR166 pKa = 11.84FCVPYY171 pKa = 9.08PYY173 pKa = 11.63AMIKK177 pKa = 10.1CEE179 pKa = 3.78EE180 pKa = 4.15WCWYY184 pKa = 8.75KK185 pKa = 11.11ARR187 pKa = 11.84GKK189 pKa = 9.89IQINCTRR196 pKa = 11.84AVVVSCTHH204 pKa = 5.61NMPLAGIKK212 pKa = 9.49RR213 pKa = 11.84VYY215 pKa = 9.0WDD217 pKa = 3.66KK218 pKa = 11.48KK219 pKa = 10.31DD220 pKa = 3.67EE221 pKa = 4.25KK222 pKa = 10.83EE223 pKa = 4.03MKK225 pKa = 10.26FMNIKK230 pKa = 10.12ACNTSAMRR238 pKa = 11.84CHH240 pKa = 6.28DD241 pKa = 3.69TKK243 pKa = 11.15VNPGGCVEE251 pKa = 5.37GYY253 pKa = 8.46PIPVGTEE260 pKa = 3.97IIPEE264 pKa = 4.09SFKK267 pKa = 11.04DD268 pKa = 3.5LRR270 pKa = 11.84EE271 pKa = 4.01EE272 pKa = 3.89KK273 pKa = 10.57SPYY276 pKa = 10.69GVIKK280 pKa = 10.6DD281 pKa = 3.75AAGKK285 pKa = 9.78LDD287 pKa = 3.28KK288 pKa = 10.63PLTVRR293 pKa = 11.84VWVRR297 pKa = 11.84LANVTGWVNGTPPFWQHH314 pKa = 7.02RR315 pKa = 11.84INGSTGINGTRR326 pKa = 11.84WYY328 pKa = 9.32GTEE331 pKa = 3.87TLTHH335 pKa = 6.63LGYY338 pKa = 10.77NISSNPEE345 pKa = 3.32AGICNKK351 pKa = 9.0TGKK354 pKa = 9.58IRR356 pKa = 11.84IGNKK360 pKa = 8.78EE361 pKa = 3.98FNLVYY366 pKa = 10.46APSWNCSQNWTGYY379 pKa = 8.04PVWHH383 pKa = 7.35IFRR386 pKa = 11.84HH387 pKa = 5.99LDD389 pKa = 3.19MTEE392 pKa = 4.37DD393 pKa = 3.24KK394 pKa = 10.6TSRR397 pKa = 11.84CMQRR401 pKa = 11.84PQRR404 pKa = 11.84KK405 pKa = 9.52NITIGNNTVIGNCSAQKK422 pKa = 10.02WDD424 pKa = 3.21GCTCNRR430 pKa = 11.84SGNWLRR436 pKa = 11.84NSTTGNIMIVVCRR449 pKa = 11.84EE450 pKa = 3.2NATLVGILEE459 pKa = 4.42GEE461 pKa = 4.45KK462 pKa = 10.34NWTQVDD468 pKa = 3.75EE469 pKa = 4.58IMRR472 pKa = 11.84KK473 pKa = 8.4NCSSEE478 pKa = 4.07EE479 pKa = 4.0QCNGTGIEE487 pKa = 4.02ALRR490 pKa = 11.84NIGGGTLGGVQNTNCTLPHH509 pKa = 6.45RR510 pKa = 11.84NEE512 pKa = 4.12TGHH515 pKa = 5.37WTCKK519 pKa = 9.86PRR521 pKa = 11.84TKK523 pKa = 10.33EE524 pKa = 3.81GKK526 pKa = 8.46TDD528 pKa = 3.11SLYY531 pKa = 10.4IGGKK535 pKa = 9.36KK536 pKa = 10.11LYY538 pKa = 9.94EE539 pKa = 3.96RR540 pKa = 11.84VKK542 pKa = 10.68AQYY545 pKa = 10.4SCEE548 pKa = 4.2SNLGGIDD555 pKa = 3.96VMVHH559 pKa = 4.37QQLMLQKK566 pKa = 8.69YY567 pKa = 9.39QIVQVRR573 pKa = 11.84TYY575 pKa = 8.76TYY577 pKa = 10.94GVVEE581 pKa = 4.71MPAEE585 pKa = 3.91YY586 pKa = 10.65AEE588 pKa = 4.1PSRR591 pKa = 11.84RR592 pKa = 11.84RR593 pKa = 11.84KK594 pKa = 10.07KK595 pKa = 10.48RR596 pKa = 11.84DD597 pKa = 2.83TSLARR602 pKa = 11.84KK603 pKa = 9.04KK604 pKa = 10.56RR605 pKa = 11.84GVGLVIVLVIMAIIAVAGASLGVANTVQQSEE636 pKa = 4.42TRR638 pKa = 11.84TAVQEE643 pKa = 4.14LANATAIQQQVLEE656 pKa = 4.24AAYY659 pKa = 10.91AMVQHH664 pKa = 5.89VAKK667 pKa = 10.52GIRR670 pKa = 11.84ILEE673 pKa = 3.97ARR675 pKa = 11.84VARR678 pKa = 11.84VEE680 pKa = 4.0ALVDD684 pKa = 3.88RR685 pKa = 11.84MMLYY689 pKa = 10.13QEE691 pKa = 4.12IDD693 pKa = 2.94CWHH696 pKa = 5.38YY697 pKa = 10.71HH698 pKa = 6.05GYY700 pKa = 10.41CVTSTRR706 pKa = 11.84SEE708 pKa = 3.94VANYY712 pKa = 10.0INWTRR717 pKa = 11.84YY718 pKa = 9.52RR719 pKa = 11.84DD720 pKa = 3.46NCTWQEE726 pKa = 3.75WEE728 pKa = 4.42KK729 pKa = 10.84EE730 pKa = 4.16IEE732 pKa = 4.0AHH734 pKa = 6.55EE735 pKa = 4.79GNLTQLIRR743 pKa = 11.84QSALATHH750 pKa = 7.09IAHH753 pKa = 7.4RR754 pKa = 11.84DD755 pKa = 3.09ASRR758 pKa = 11.84IPDD761 pKa = 3.16VWKK764 pKa = 10.56ALQQAFNWSGWFSWLKK780 pKa = 8.72YY781 pKa = 9.8LPWVIVGIIGIICIRR796 pKa = 11.84IGACVLGICAQSYY809 pKa = 9.46RR810 pKa = 11.84QLKK813 pKa = 8.66SLQYY817 pKa = 10.44QIIEE821 pKa = 3.82LDD823 pKa = 3.67LRR825 pKa = 11.84EE826 pKa = 4.07KK827 pKa = 10.91AIGCEE832 pKa = 4.23GEE834 pKa = 4.15EE835 pKa = 4.41GGEE838 pKa = 4.24DD839 pKa = 3.43EE840 pKa = 5.48AGSDD844 pKa = 3.6GFANCVLEE852 pKa = 4.91DD853 pKa = 4.18SPSLIQIWRR862 pKa = 11.84TQYY865 pKa = 10.22QEE867 pKa = 3.51WRR869 pKa = 11.84RR870 pKa = 11.84SPWATLEE877 pKa = 4.0KK878 pKa = 10.76ARR880 pKa = 11.84TLMVLPVTATEE891 pKa = 3.75QWLRR895 pKa = 11.84DD896 pKa = 3.72CGRR899 pKa = 11.84LGDD902 pKa = 3.78RR903 pKa = 11.84LKK905 pKa = 11.08NKK907 pKa = 9.71KK908 pKa = 9.86KK909 pKa = 10.55RR910 pKa = 11.84VDD912 pKa = 3.59CEE914 pKa = 4.21GQEE917 pKa = 4.34SRR919 pKa = 11.84PHH921 pKa = 4.48WTEE924 pKa = 3.47TT925 pKa = 3.27

Molecular weight: 105.86 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|C9DI74|C9DI74_CAEV Rev protein OS=Caprine arthritis encephalitis virus OX=11660 GN=rev PE=4 SV=1
MM1 pKa = 7.93DD2 pKa = 4.9KK3 pKa = 10.93KK4 pKa = 10.68DD5 pKa = 3.54GKK7 pKa = 9.07RR8 pKa = 11.84TRR10 pKa = 11.84TEE12 pKa = 3.84EE13 pKa = 4.0PPLRR17 pKa = 11.84EE18 pKa = 3.45VWRR21 pKa = 11.84QVMSEE26 pKa = 3.84YY27 pKa = 10.26RR28 pKa = 11.84SRR30 pKa = 11.84YY31 pKa = 9.11PEE33 pKa = 3.99LQATEE38 pKa = 4.09EE39 pKa = 4.34LAVSDD44 pKa = 4.6HH45 pKa = 5.79RR46 pKa = 11.84TGPKK50 pKa = 10.06GEE52 pKa = 4.27GYY54 pKa = 10.7RR55 pKa = 11.84MRR57 pKa = 11.84GRR59 pKa = 11.84RR60 pKa = 11.84RR61 pKa = 11.84RR62 pKa = 11.84RR63 pKa = 11.84GRR65 pKa = 11.84GWFRR69 pKa = 11.84WLRR72 pKa = 11.84KK73 pKa = 9.27LRR75 pKa = 11.84ARR77 pKa = 11.84RR78 pKa = 11.84FTEE81 pKa = 4.08PDD83 pKa = 3.51PDD85 pKa = 4.72LEE87 pKa = 4.75DD88 pKa = 4.19PVPGMEE94 pKa = 4.38TLTLGDD100 pKa = 4.29PGEE103 pKa = 4.56GADD106 pKa = 3.74TDD108 pKa = 4.32GAAGDD113 pKa = 3.75SDD115 pKa = 4.03GAVAAGLWTAWRR127 pKa = 11.84SPQKK131 pKa = 10.92

Molecular weight: 15.04 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

2706

131

981

541.2

62.14

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.098 ± 0.609

2.476 ± 0.676

4.028 ± 0.562

7.613 ± 0.487

1.959 ± 0.434

7.724 ± 0.416

2.217 ± 0.324

5.802 ± 1.187

7.28 ± 0.7

7.724 ± 0.616

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.624 ± 0.25

3.88 ± 0.71

5.1 ± 0.513

5.876 ± 0.671

7.058 ± 1.157

4.102 ± 0.203

5.802 ± 0.466

5.876 ± 0.486

3.474 ± 0.621

3.289 ± 0.296
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski