Amino acid dipepetide frequency for Beihai picorna-like virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.41AlaAla: 7.41 ± 1.72
1.56AlaCys: 1.56 ± 0.204
6.63AlaAsp: 6.63 ± 0.873
3.12AlaGlu: 3.12 ± 0.857
5.07AlaPhe: 5.07 ± 1.453
3.12AlaGly: 3.12 ± 0.857
0.39AlaHis: 0.39 ± 0.209
4.29AlaIle: 4.29 ± 0.863
5.46AlaLys: 5.46 ± 0.397
4.68AlaLeu: 4.68 ± 0.654
2.73AlaMet: 2.73 ± 0.165
5.85AlaAsn: 5.85 ± 1.924
3.51AlaPro: 3.51 ± 0.016
3.9AlaGln: 3.9 ± 1.458
2.34AlaArg: 2.34 ± 0.622
5.85AlaSer: 5.85 ± 0.659
4.29AlaThr: 4.29 ± 0.863
5.46AlaVal: 5.46 ± 0.236
0.78AlaTrp: 0.78 ± 0.847
2.73AlaTyr: 2.73 ± 1.463
0.0AlaXaa: 0.0 ± 0.0
Cys
1.95CysAla: 1.95 ± 1.045
1.17CysCys: 1.17 ± 0.005
1.17CysAsp: 1.17 ± 0.627
0.39CysGlu: 0.39 ± 0.209
1.56CysPhe: 1.56 ± 0.429
1.95CysGly: 1.95 ± 1.045
0.78CysHis: 0.78 ± 0.418
1.17CysIle: 1.17 ± 0.627
1.95CysLys: 1.95 ± 0.22
1.95CysLeu: 1.95 ± 0.413
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.78CysPro: 0.78 ± 0.418
0.39CysGln: 0.39 ± 0.209
0.78CysArg: 0.78 ± 0.214
1.56CysSer: 1.56 ± 0.836
1.17CysThr: 1.17 ± 0.627
1.95CysVal: 1.95 ± 0.413
0.78CysTrp: 0.78 ± 0.418
0.39CysTyr: 0.39 ± 0.209
0.0CysXaa: 0.0 ± 0.0
Asp
4.29AspAla: 4.29 ± 0.863
0.0AspCys: 0.0 ± 0.0
3.51AspAsp: 3.51 ± 1.249
3.51AspGlu: 3.51 ± 0.648
3.51AspPhe: 3.51 ± 0.648
2.34AspGly: 2.34 ± 0.011
1.17AspHis: 1.17 ± 0.005
5.46AspIle: 5.46 ± 0.397
3.51AspLys: 3.51 ± 1.882
5.85AspLeu: 5.85 ± 0.027
1.56AspMet: 1.56 ± 0.836
1.56AspAsn: 1.56 ± 0.836
3.9AspPro: 3.9 ± 2.969
2.34AspGln: 2.34 ± 1.276
4.68AspArg: 4.68 ± 1.244
3.12AspSer: 3.12 ± 0.225
1.56AspThr: 1.56 ± 0.429
4.68AspVal: 4.68 ± 1.244
0.78AspTrp: 0.78 ± 0.418
1.95AspTyr: 1.95 ± 0.413
0.0AspXaa: 0.0 ± 0.0
Glu
3.9GluAla: 3.9 ± 0.826
1.95GluCys: 1.95 ± 1.045
3.9GluAsp: 3.9 ± 0.193
5.07GluGlu: 5.07 ± 0.188
2.73GluPhe: 2.73 ± 1.463
1.56GluGly: 1.56 ± 0.836
0.78GluHis: 0.78 ± 0.418
1.56GluIle: 1.56 ± 0.204
5.07GluLys: 5.07 ± 2.085
3.9GluLeu: 3.9 ± 0.439
3.51GluMet: 3.51 ± 0.617
3.9GluAsn: 3.9 ± 0.826
3.51GluPro: 3.51 ± 0.648
1.17GluGln: 1.17 ± 0.627
3.51GluArg: 3.51 ± 1.249
2.34GluSer: 2.34 ± 1.276
3.9GluThr: 3.9 ± 1.072
5.46GluVal: 5.46 ± 1.501
1.95GluTrp: 1.95 ± 0.413
1.95GluTyr: 1.95 ± 0.22
0.0GluXaa: 0.0 ± 0.0
Phe
2.34PheAla: 2.34 ± 0.011
0.39PheCys: 0.39 ± 0.209
2.34PheAsp: 2.34 ± 0.011
5.46PheGlu: 5.46 ± 0.397
3.12PhePhe: 3.12 ± 1.49
2.34PheGly: 2.34 ± 0.011
1.56PheHis: 1.56 ± 0.429
1.56PheIle: 1.56 ± 0.204
2.34PheLys: 2.34 ± 1.254
3.51PheLeu: 3.51 ± 1.249
0.39PheMet: 0.39 ± 0.209
2.73PheAsn: 2.73 ± 1.699
3.51PhePro: 3.51 ± 0.617
1.17PheGln: 1.17 ± 0.005
5.07PheArg: 5.07 ± 0.188
3.12PheSer: 3.12 ± 0.225
3.9PheThr: 3.9 ± 1.704
2.34PheVal: 2.34 ± 0.643
0.78PheTrp: 0.78 ± 0.418
1.17PheTyr: 1.17 ± 0.005
0.0PheXaa: 0.0 ± 0.0
Gly
6.24GlyAla: 6.24 ± 1.715
0.78GlyCys: 0.78 ± 0.418
3.12GlyAsp: 3.12 ± 0.225
3.51GlyGlu: 3.51 ± 0.016
2.34GlyPhe: 2.34 ± 0.643
6.63GlyGly: 6.63 ± 0.392
0.39GlyHis: 0.39 ± 0.423
4.68GlyIle: 4.68 ± 0.021
1.95GlyLys: 1.95 ± 1.045
3.12GlyLeu: 3.12 ± 0.408
1.56GlyMet: 1.56 ± 0.429
4.68GlyAsn: 4.68 ± 1.286
2.34GlyPro: 2.34 ± 0.011
1.56GlyGln: 1.56 ± 0.204
2.73GlyArg: 2.73 ± 0.198
3.12GlySer: 3.12 ± 0.408
3.51GlyThr: 3.51 ± 1.281
3.51GlyVal: 3.51 ± 1.249
1.17GlyTrp: 1.17 ± 0.638
2.73GlyTyr: 2.73 ± 0.198
0.0GlyXaa: 0.0 ± 0.0
His
1.95HisAla: 1.95 ± 0.413
0.39HisCys: 0.39 ± 0.423
1.17HisAsp: 1.17 ± 0.627
1.56HisGlu: 1.56 ± 0.429
0.39HisPhe: 0.39 ± 0.423
1.56HisGly: 1.56 ± 0.204
0.39HisHis: 0.39 ± 0.209
1.17HisIle: 1.17 ± 0.627
1.56HisLys: 1.56 ± 0.204
0.78HisLeu: 0.78 ± 0.418
1.17HisMet: 1.17 ± 0.005
0.78HisAsn: 0.78 ± 0.847
0.78HisPro: 0.78 ± 0.418
0.78HisGln: 0.78 ± 0.214
0.78HisArg: 0.78 ± 0.214
0.39HisSer: 0.39 ± 0.423
0.78HisThr: 0.78 ± 0.847
1.56HisVal: 1.56 ± 0.204
0.39HisTrp: 0.39 ± 0.423
0.78HisTyr: 0.78 ± 0.214
0.0HisXaa: 0.0 ± 0.0
Ile
5.46IleAla: 5.46 ± 0.397
1.56IleCys: 1.56 ± 0.204
3.9IleAsp: 3.9 ± 0.826
3.12IleGlu: 3.12 ± 0.408
2.34IlePhe: 2.34 ± 1.254
5.85IleGly: 5.85 ± 1.871
1.56IleHis: 1.56 ± 0.429
2.73IleIle: 2.73 ± 2.332
1.95IleLys: 1.95 ± 0.413
1.17IleLeu: 1.17 ± 0.627
1.56IleMet: 1.56 ± 0.836
1.56IleAsn: 1.56 ± 0.429
5.46IlePro: 5.46 ± 2.766
3.12IleGln: 3.12 ± 0.225
1.95IleArg: 1.95 ± 1.045
2.73IleSer: 2.73 ± 0.198
5.85IleThr: 5.85 ± 0.027
4.29IleVal: 4.29 ± 0.402
0.39IleTrp: 0.39 ± 0.423
1.17IleTyr: 1.17 ± 0.627
0.0IleXaa: 0.0 ± 0.0
Lys
4.29LysAla: 4.29 ± 1.035
1.56LysCys: 1.56 ± 0.836
3.9LysAsp: 3.9 ± 0.826
5.46LysGlu: 5.46 ± 1.662
4.68LysPhe: 4.68 ± 1.244
4.29LysGly: 4.29 ± 1.667
1.17LysHis: 1.17 ± 0.005
1.56LysIle: 1.56 ± 0.429
3.9LysLys: 3.9 ± 1.458
2.73LysLeu: 2.73 ± 0.198
3.12LysMet: 3.12 ± 1.04
2.34LysAsn: 2.34 ± 1.254
2.73LysPro: 2.73 ± 0.831
0.78LysGln: 0.78 ± 0.214
2.73LysArg: 2.73 ± 0.198
6.63LysSer: 6.63 ± 2.289
1.17LysThr: 1.17 ± 0.627
4.68LysVal: 4.68 ± 1.876
1.17LysTrp: 1.17 ± 0.627
2.73LysTyr: 2.73 ± 0.831
0.0LysXaa: 0.0 ± 0.0
Leu
4.29LeuAla: 4.29 ± 1.035
1.56LeuCys: 1.56 ± 0.836
4.29LeuAsp: 4.29 ± 0.402
2.34LeuGlu: 2.34 ± 0.622
1.56LeuPhe: 1.56 ± 0.204
4.29LeuGly: 4.29 ± 0.863
1.56LeuHis: 1.56 ± 1.061
5.07LeuIle: 5.07 ± 0.82
6.63LeuLys: 6.63 ± 1.024
8.97LeuLeu: 8.97 ± 2.279
2.73LeuMet: 2.73 ± 0.831
1.95LeuAsn: 1.95 ± 0.852
3.12LeuPro: 3.12 ± 0.408
1.95LeuGln: 1.95 ± 1.045
5.07LeuArg: 5.07 ± 0.188
4.68LeuSer: 4.68 ± 0.654
6.24LeuThr: 6.24 ± 1.715
2.73LeuVal: 2.73 ± 0.831
1.17LeuTrp: 1.17 ± 0.638
3.12LeuTyr: 3.12 ± 1.673
0.0LeuXaa: 0.0 ± 0.0
Met
3.12MetAla: 3.12 ± 0.857
0.0MetCys: 0.0 ± 0.0
1.17MetAsp: 1.17 ± 0.627
1.56MetGlu: 1.56 ± 0.836
0.78MetPhe: 0.78 ± 0.214
1.95MetGly: 1.95 ± 0.852
0.0MetHis: 0.0 ± 0.0
2.34MetIle: 2.34 ± 0.622
3.12MetLys: 3.12 ± 0.408
2.73MetLeu: 2.73 ± 1.463
1.17MetMet: 1.17 ± 0.005
0.78MetAsn: 0.78 ± 0.847
3.12MetPro: 3.12 ± 0.408
1.17MetGln: 1.17 ± 0.005
0.78MetArg: 0.78 ± 0.418
1.17MetSer: 1.17 ± 0.005
1.17MetThr: 1.17 ± 0.638
1.56MetVal: 1.56 ± 0.204
0.78MetTrp: 0.78 ± 0.418
1.95MetTyr: 1.95 ± 0.413
0.0MetXaa: 0.0 ± 0.0
Asn
1.95AsnAla: 1.95 ± 0.22
0.78AsnCys: 0.78 ± 0.418
2.34AsnAsp: 2.34 ± 1.276
3.12AsnGlu: 3.12 ± 0.857
3.51AsnPhe: 3.51 ± 0.016
3.51AsnGly: 3.51 ± 0.648
1.56AsnHis: 1.56 ± 0.204
2.34AsnIle: 2.34 ± 0.011
1.56AsnLys: 1.56 ± 0.204
5.46AsnLeu: 5.46 ± 1.501
1.17AsnMet: 1.17 ± 0.005
2.73AsnAsn: 2.73 ± 0.434
1.95AsnPro: 1.95 ± 0.852
1.56AsnGln: 1.56 ± 1.061
0.78AsnArg: 0.78 ± 0.214
2.34AsnSer: 2.34 ± 1.276
3.12AsnThr: 3.12 ± 0.857
5.07AsnVal: 5.07 ± 1.077
1.17AsnTrp: 1.17 ± 0.627
2.34AsnTyr: 2.34 ± 1.908
0.0AsnXaa: 0.0 ± 0.0
Pro
4.29ProAla: 4.29 ± 1.495
0.39ProCys: 0.39 ± 0.209
3.12ProAsp: 3.12 ± 0.857
1.95ProGlu: 1.95 ± 1.045
2.34ProPhe: 2.34 ± 1.276
1.95ProGly: 1.95 ± 1.485
1.17ProHis: 1.17 ± 0.638
2.34ProIle: 2.34 ± 0.011
3.9ProLys: 3.9 ± 2.091
5.07ProLeu: 5.07 ± 1.453
0.78ProMet: 0.78 ± 0.847
1.95ProAsn: 1.95 ± 0.22
0.78ProPro: 0.78 ± 0.418
5.07ProGln: 5.07 ± 1.077
1.17ProArg: 1.17 ± 0.005
2.34ProSer: 2.34 ± 0.011
5.46ProThr: 5.46 ± 0.236
3.9ProVal: 3.9 ± 1.704
1.17ProTrp: 1.17 ± 0.005
2.73ProTyr: 2.73 ± 1.699
0.0ProXaa: 0.0 ± 0.0
Gln
2.73GlnAla: 2.73 ± 0.831
1.17GlnCys: 1.17 ± 0.005
1.95GlnAsp: 1.95 ± 0.852
2.34GlnGlu: 2.34 ± 1.276
1.17GlnPhe: 1.17 ± 0.638
2.73GlnGly: 2.73 ± 0.198
0.78GlnHis: 0.78 ± 0.214
1.56GlnIle: 1.56 ± 0.836
1.95GlnLys: 1.95 ± 0.413
1.56GlnLeu: 1.56 ± 0.836
1.56GlnMet: 1.56 ± 0.429
1.95GlnAsn: 1.95 ± 0.852
0.78GlnPro: 0.78 ± 0.847
0.78GlnGln: 0.78 ± 0.214
2.73GlnArg: 2.73 ± 0.198
0.78GlnSer: 0.78 ± 0.847
1.95GlnThr: 1.95 ± 0.22
3.12GlnVal: 3.12 ± 0.225
1.56GlnTrp: 1.56 ± 0.204
0.39GlnTyr: 0.39 ± 0.209
0.0GlnXaa: 0.0 ± 0.0
Arg
4.29ArgAla: 4.29 ± 1.035
2.34ArgCys: 2.34 ± 0.622
4.68ArgAsp: 4.68 ± 0.611
4.68ArgGlu: 4.68 ± 0.611
3.12ArgPhe: 3.12 ± 0.408
2.34ArgGly: 2.34 ± 0.643
1.17ArgHis: 1.17 ± 0.627
5.46ArgIle: 5.46 ± 1.029
2.34ArgLys: 2.34 ± 1.254
2.34ArgLeu: 2.34 ± 0.622
0.78ArgMet: 0.78 ± 0.418
1.95ArgAsn: 1.95 ± 0.22
2.73ArgPro: 2.73 ± 1.699
1.95ArgGln: 1.95 ± 0.22
2.73ArgArg: 2.73 ± 0.198
0.78ArgSer: 0.78 ± 0.418
1.17ArgThr: 1.17 ± 0.005
3.51ArgVal: 3.51 ± 0.648
2.34ArgTrp: 2.34 ± 0.011
0.39ArgTyr: 0.39 ± 0.423
0.0ArgXaa: 0.0 ± 0.0
Ser
4.29SerAla: 4.29 ± 1.495
0.78SerCys: 0.78 ± 0.418
1.95SerAsp: 1.95 ± 0.852
4.29SerGlu: 4.29 ± 1.667
1.56SerPhe: 1.56 ± 1.061
2.73SerGly: 2.73 ± 0.434
0.78SerHis: 0.78 ± 0.418
4.68SerIle: 4.68 ± 1.244
3.51SerLys: 3.51 ± 1.882
4.68SerLeu: 4.68 ± 0.021
1.17SerMet: 1.17 ± 0.857
3.9SerAsn: 3.9 ± 0.193
2.34SerPro: 2.34 ± 0.643
2.73SerGln: 2.73 ± 1.699
3.12SerArg: 3.12 ± 0.857
2.73SerSer: 2.73 ± 1.067
3.51SerThr: 3.51 ± 1.913
4.29SerVal: 4.29 ± 0.23
0.39SerTrp: 0.39 ± 0.423
3.51SerTyr: 3.51 ± 0.648
0.0SerXaa: 0.0 ± 0.0
Thr
3.9ThrAla: 3.9 ± 1.072
1.56ThrCys: 1.56 ± 0.204
3.9ThrAsp: 3.9 ± 0.826
1.95ThrGlu: 1.95 ± 0.413
2.73ThrPhe: 2.73 ± 0.198
3.12ThrGly: 3.12 ± 1.49
0.78ThrHis: 0.78 ± 0.418
2.73ThrIle: 2.73 ± 1.699
4.29ThrLys: 4.29 ± 1.035
7.02ThrLeu: 7.02 ± 1.929
1.56ThrMet: 1.56 ± 0.429
3.9ThrAsn: 3.9 ± 2.337
3.12ThrPro: 3.12 ± 0.857
0.78ThrGln: 0.78 ± 0.847
3.51ThrArg: 3.51 ± 0.617
3.9ThrSer: 3.9 ± 2.969
2.73ThrThr: 2.73 ± 0.198
4.29ThrVal: 4.29 ± 0.23
0.39ThrTrp: 0.39 ± 0.423
1.17ThrTyr: 1.17 ± 0.638
0.0ThrXaa: 0.0 ± 0.0
Val
6.24ValAla: 6.24 ± 0.45
2.73ValCys: 2.73 ± 1.463
1.56ValAsp: 1.56 ± 0.429
5.46ValGlu: 5.46 ± 1.662
3.12ValPhe: 3.12 ± 1.49
3.51ValGly: 3.51 ± 0.648
1.95ValHis: 1.95 ± 0.22
2.73ValIle: 2.73 ± 0.831
4.29ValLys: 4.29 ± 1.035
5.07ValLeu: 5.07 ± 0.188
1.56ValMet: 1.56 ± 0.204
2.73ValAsn: 2.73 ± 0.434
5.46ValPro: 5.46 ± 1.029
0.78ValGln: 0.78 ± 0.418
3.51ValArg: 3.51 ± 0.016
5.07ValSer: 5.07 ± 1.71
3.51ValThr: 3.51 ± 0.648
6.63ValVal: 6.63 ± 0.241
2.34ValTrp: 2.34 ± 0.011
2.73ValTyr: 2.73 ± 0.434
0.0ValXaa: 0.0 ± 0.0
Trp
1.56TrpAla: 1.56 ± 1.061
0.39TrpCys: 0.39 ± 0.209
2.34TrpAsp: 2.34 ± 0.011
1.17TrpGlu: 1.17 ± 0.005
1.17TrpPhe: 1.17 ± 0.005
0.78TrpGly: 0.78 ± 0.214
0.0TrpHis: 0.0 ± 0.0
1.56TrpIle: 1.56 ± 0.836
1.56TrpLys: 1.56 ± 0.204
1.17TrpLeu: 1.17 ± 0.627
1.56TrpMet: 1.56 ± 0.204
0.78TrpAsn: 0.78 ± 0.847
0.0TrpPro: 0.0 ± 0.0
1.17TrpGln: 1.17 ± 0.005
1.56TrpArg: 1.56 ± 1.061
0.39TrpSer: 0.39 ± 0.209
0.78TrpThr: 0.78 ± 0.418
1.56TrpVal: 1.56 ± 0.836
0.39TrpTrp: 0.39 ± 0.209
0.39TrpTyr: 0.39 ± 0.423
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.68TyrAla: 4.68 ± 0.021
0.78TyrCys: 0.78 ± 0.214
2.34TyrAsp: 2.34 ± 0.011
1.56TyrGlu: 1.56 ± 0.204
2.34TyrPhe: 2.34 ± 0.622
3.12TyrGly: 3.12 ± 0.225
1.17TyrHis: 1.17 ± 0.638
2.73TyrIle: 2.73 ± 0.434
0.78TyrLys: 0.78 ± 0.214
1.56TyrLeu: 1.56 ± 0.204
0.39TyrMet: 0.39 ± 0.209
2.34TyrAsn: 2.34 ± 0.643
1.95TyrPro: 1.95 ± 0.413
0.39TyrGln: 0.39 ± 0.209
1.56TyrArg: 1.56 ± 0.204
4.29TyrSer: 4.29 ± 0.402
1.56TyrThr: 1.56 ± 0.429
0.39TyrVal: 0.39 ± 0.423
0.39TyrTrp: 0.39 ± 0.209
2.34TyrTyr: 2.34 ± 0.011
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski