Amino acid dipepetide frequency for Spinach cryptic virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.066AlaAla: 9.066 ± 5.802
0.0AlaCys: 0.0 ± 0.0
3.626AlaAsp: 3.626 ± 0.294
4.533AlaGlu: 4.533 ± 0.266
2.72AlaPhe: 2.72 ± 1.68
2.72AlaGly: 2.72 ± 0.413
3.626AlaHis: 3.626 ± 1.561
6.346AlaIle: 6.346 ± 1.148
0.0AlaLys: 0.0 ± 0.0
6.346AlaLeu: 6.346 ± 1.148
1.813AlaMet: 1.813 ± 1.414
4.533AlaAsn: 4.533 ± 1.001
7.253AlaPro: 7.253 ± 1.855
5.44AlaGln: 5.44 ± 0.441
5.44AlaArg: 5.44 ± 0.441
4.533AlaSer: 4.533 ± 2.268
5.44AlaThr: 5.44 ± 0.441
2.72AlaVal: 2.72 ± 2.121
1.813AlaTrp: 1.813 ± 0.147
2.72AlaTyr: 2.72 ± 0.413
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.907CysAsp: 0.907 ± 0.707
0.907CysGlu: 0.907 ± 0.56
0.0CysPhe: 0.0 ± 0.0
2.72CysGly: 2.72 ± 0.413
0.0CysHis: 0.0 ± 0.0
0.907CysIle: 0.907 ± 0.56
0.0CysLys: 0.0 ± 0.0
0.907CysLeu: 0.907 ± 0.707
0.907CysMet: 0.907 ± 0.56
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.907CysGln: 0.907 ± 0.707
0.907CysArg: 0.907 ± 0.56
0.907CysSer: 0.907 ± 0.56
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.907CysTrp: 0.907 ± 0.707
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.72AspAla: 2.72 ± 0.854
0.0AspCys: 0.0 ± 0.0
0.907AspAsp: 0.907 ± 0.56
4.533AspGlu: 4.533 ± 1.533
2.72AspPhe: 2.72 ± 1.68
0.907AspGly: 0.907 ± 0.56
2.72AspHis: 2.72 ± 0.413
4.533AspIle: 4.533 ± 1.533
1.813AspLys: 1.813 ± 1.12
0.907AspLeu: 0.907 ± 0.56
0.0AspMet: 0.0 ± 0.0
1.813AspAsn: 1.813 ± 1.414
4.533AspPro: 4.533 ± 1.533
3.626AspGln: 3.626 ± 0.294
0.907AspArg: 0.907 ± 0.707
3.626AspSer: 3.626 ± 0.973
0.0AspThr: 0.0 ± 0.0
2.72AspVal: 2.72 ± 1.68
1.813AspTrp: 1.813 ± 0.147
1.813AspTyr: 1.813 ± 1.12
0.0AspXaa: 0.0 ± 0.0
Glu
2.72GluAla: 2.72 ± 0.413
0.907GluCys: 0.907 ± 0.707
0.0GluAsp: 0.0 ± 0.0
0.907GluGlu: 0.907 ± 0.707
1.813GluPhe: 1.813 ± 0.147
0.907GluGly: 0.907 ± 0.56
3.626GluHis: 3.626 ± 0.973
5.44GluIle: 5.44 ± 2.093
0.0GluLys: 0.0 ± 0.0
1.813GluLeu: 1.813 ± 1.414
0.0GluMet: 0.0 ± 0.425
2.72GluAsn: 2.72 ± 1.68
1.813GluPro: 1.813 ± 1.12
4.533GluGln: 4.533 ± 2.268
0.907GluArg: 0.907 ± 0.56
2.72GluSer: 2.72 ± 0.413
3.626GluThr: 3.626 ± 0.294
1.813GluVal: 1.813 ± 1.12
1.813GluTrp: 1.813 ± 1.414
5.44GluTyr: 5.44 ± 3.359
0.0GluXaa: 0.0 ± 0.0
Phe
3.626PheAla: 3.626 ± 0.294
0.907PheCys: 0.907 ± 0.56
5.44PheAsp: 5.44 ± 2.093
5.44PheGlu: 5.44 ± 0.441
2.72PhePhe: 2.72 ± 0.413
3.626PheGly: 3.626 ± 0.973
0.907PheHis: 0.907 ± 0.707
3.626PheIle: 3.626 ± 2.24
0.907PheLys: 0.907 ± 0.707
3.626PheLeu: 3.626 ± 2.24
1.813PheMet: 1.813 ± 1.12
3.626PheAsn: 3.626 ± 0.294
3.626PhePro: 3.626 ± 0.973
2.72PheGln: 2.72 ± 0.854
2.72PheArg: 2.72 ± 1.68
7.253PheSer: 7.253 ± 0.588
3.626PheThr: 3.626 ± 0.294
1.813PheVal: 1.813 ± 1.414
0.907PheTrp: 0.907 ± 0.707
2.72PheTyr: 2.72 ± 0.413
0.0PheXaa: 0.0 ± 0.0
Gly
7.253GlyAla: 7.253 ± 4.388
0.907GlyCys: 0.907 ± 0.56
4.533GlyAsp: 4.533 ± 1.533
0.907GlyGlu: 0.907 ± 0.56
5.44GlyPhe: 5.44 ± 2.093
0.907GlyGly: 0.907 ± 0.56
0.907GlyHis: 0.907 ± 0.707
2.72GlyIle: 2.72 ± 0.854
0.907GlyLys: 0.907 ± 0.56
4.533GlyLeu: 4.533 ± 2.799
0.0GlyMet: 0.0 ± 0.0
0.907GlyAsn: 0.907 ± 0.56
5.44GlyPro: 5.44 ± 2.975
1.813GlyGln: 1.813 ± 1.414
0.907GlyArg: 0.907 ± 0.56
1.813GlySer: 1.813 ± 1.414
2.72GlyThr: 2.72 ± 2.121
0.0GlyVal: 0.0 ± 0.0
0.907GlyTrp: 0.907 ± 0.56
4.533GlyTyr: 4.533 ± 1.533
0.0GlyXaa: 0.0 ± 0.0
His
3.626HisAla: 3.626 ± 1.561
0.0HisCys: 0.0 ± 0.0
0.907HisAsp: 0.907 ± 0.56
3.626HisGlu: 3.626 ± 0.973
2.72HisPhe: 2.72 ± 0.413
3.626HisGly: 3.626 ± 0.294
0.907HisHis: 0.907 ± 0.56
2.72HisIle: 2.72 ± 0.413
0.907HisLys: 0.907 ± 0.56
2.72HisLeu: 2.72 ± 2.121
0.0HisMet: 0.0 ± 0.0
0.907HisAsn: 0.907 ± 0.56
1.813HisPro: 1.813 ± 1.12
1.813HisGln: 1.813 ± 0.147
1.813HisArg: 1.813 ± 0.147
0.907HisSer: 0.907 ± 0.707
3.626HisThr: 3.626 ± 0.294
2.72HisVal: 2.72 ± 0.413
0.907HisTrp: 0.907 ± 0.56
0.907HisTyr: 0.907 ± 0.707
0.0HisXaa: 0.0 ± 0.0
Ile
3.626IleAla: 3.626 ± 0.973
0.0IleCys: 0.0 ± 0.0
2.72IleAsp: 2.72 ± 0.413
0.907IleGlu: 0.907 ± 0.56
3.626IlePhe: 3.626 ± 1.561
3.626IleGly: 3.626 ± 0.294
0.0IleHis: 0.0 ± 0.0
5.44IleIle: 5.44 ± 2.093
4.533IleLys: 4.533 ± 2.799
9.066IleLeu: 9.066 ± 0.532
0.0IleMet: 0.0 ± 0.0
1.813IleAsn: 1.813 ± 0.147
8.16IlePro: 8.16 ± 1.295
0.907IleGln: 0.907 ± 0.56
2.72IleArg: 2.72 ± 1.68
2.72IleSer: 2.72 ± 0.854
6.346IleThr: 6.346 ± 1.386
4.533IleVal: 4.533 ± 1.001
0.907IleTrp: 0.907 ± 0.56
0.907IleTyr: 0.907 ± 0.56
0.0IleXaa: 0.0 ± 0.0
Lys
2.72LysAla: 2.72 ± 1.68
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
0.0LysGlu: 0.0 ± 0.0
0.907LysPhe: 0.907 ± 0.56
0.0LysGly: 0.0 ± 0.0
0.907LysHis: 0.907 ± 0.56
0.0LysIle: 0.0 ± 0.0
2.72LysLys: 2.72 ± 1.68
1.813LysLeu: 1.813 ± 1.12
1.813LysMet: 1.813 ± 1.12
2.72LysAsn: 2.72 ± 0.413
1.813LysPro: 1.813 ± 1.12
0.907LysGln: 0.907 ± 0.56
2.72LysArg: 2.72 ± 0.413
3.626LysSer: 3.626 ± 0.294
5.44LysThr: 5.44 ± 2.093
1.813LysVal: 1.813 ± 0.147
1.813LysTrp: 1.813 ± 1.12
1.813LysTyr: 1.813 ± 0.147
0.0LysXaa: 0.0 ± 0.0
Leu
5.44LeuAla: 5.44 ± 0.826
1.813LeuCys: 1.813 ± 1.414
5.44LeuAsp: 5.44 ± 0.826
5.44LeuGlu: 5.44 ± 0.826
5.44LeuPhe: 5.44 ± 0.826
4.533LeuGly: 4.533 ± 2.268
1.813LeuHis: 1.813 ± 0.147
2.72LeuIle: 2.72 ± 0.413
3.626LeuLys: 3.626 ± 1.561
8.16LeuLeu: 8.16 ± 1.295
0.0LeuMet: 0.0 ± 0.0
4.533LeuAsn: 4.533 ± 1.533
1.813LeuPro: 1.813 ± 0.147
0.0LeuGln: 0.0 ± 0.0
7.253LeuArg: 7.253 ± 0.588
5.44LeuSer: 5.44 ± 0.441
11.786LeuThr: 11.786 ± 3.478
2.72LeuVal: 2.72 ± 2.121
5.44LeuTrp: 5.44 ± 0.826
5.44LeuTyr: 5.44 ± 0.826
0.0LeuXaa: 0.0 ± 0.0
Met
1.813MetAla: 1.813 ± 1.12
0.907MetCys: 0.907 ± 0.707
0.907MetAsp: 0.907 ± 0.56
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
1.813MetHis: 1.813 ± 0.147
1.813MetIle: 1.813 ± 0.147
0.0MetLys: 0.0 ± 0.0
6.346MetLeu: 6.346 ± 1.386
0.907MetMet: 0.907 ± 0.707
0.907MetAsn: 0.907 ± 0.707
0.907MetPro: 0.907 ± 0.56
1.813MetGln: 1.813 ± 1.414
1.813MetArg: 1.813 ± 1.12
0.907MetSer: 0.907 ± 0.707
0.907MetThr: 0.907 ± 0.707
1.813MetVal: 1.813 ± 1.12
0.0MetTrp: 0.0 ± 0.0
1.813MetTyr: 1.813 ± 0.147
0.0MetXaa: 0.0 ± 0.0
Asn
5.44AsnAla: 5.44 ± 0.441
0.0AsnCys: 0.0 ± 0.0
1.813AsnAsp: 1.813 ± 0.147
1.813AsnGlu: 1.813 ± 1.12
1.813AsnPhe: 1.813 ± 1.12
4.533AsnGly: 4.533 ± 1.001
2.72AsnHis: 2.72 ± 1.68
2.72AsnIle: 2.72 ± 0.854
1.813AsnLys: 1.813 ± 1.12
3.626AsnLeu: 3.626 ± 0.973
1.813AsnMet: 1.813 ± 1.414
2.72AsnAsn: 2.72 ± 0.413
1.813AsnPro: 1.813 ± 1.414
0.907AsnGln: 0.907 ± 0.707
4.533AsnArg: 4.533 ± 0.266
2.72AsnSer: 2.72 ± 0.413
4.533AsnThr: 4.533 ± 1.001
2.72AsnVal: 2.72 ± 0.413
0.907AsnTrp: 0.907 ± 0.707
1.813AsnTyr: 1.813 ± 0.147
0.0AsnXaa: 0.0 ± 0.0
Pro
8.16ProAla: 8.16 ± 3.829
0.907ProCys: 0.907 ± 0.56
2.72ProAsp: 2.72 ± 0.413
3.626ProGlu: 3.626 ± 0.294
5.44ProPhe: 5.44 ± 0.441
2.72ProGly: 2.72 ± 2.121
2.72ProHis: 2.72 ± 0.854
3.626ProIle: 3.626 ± 1.561
4.533ProLys: 4.533 ± 1.533
4.533ProLeu: 4.533 ± 2.268
2.72ProMet: 2.72 ± 0.413
5.44ProAsn: 5.44 ± 0.441
4.533ProPro: 4.533 ± 1.533
2.72ProGln: 2.72 ± 2.121
4.533ProArg: 4.533 ± 0.266
2.72ProSer: 2.72 ± 0.413
8.16ProThr: 8.16 ± 0.028
0.0ProVal: 0.0 ± 0.0
0.907ProTrp: 0.907 ± 0.56
1.813ProTyr: 1.813 ± 1.12
0.0ProXaa: 0.0 ± 0.0
Gln
2.72GlnAla: 2.72 ± 0.854
0.0GlnCys: 0.0 ± 0.0
1.813GlnAsp: 1.813 ± 1.12
1.813GlnGlu: 1.813 ± 0.147
0.907GlnPhe: 0.907 ± 0.56
1.813GlnGly: 1.813 ± 0.147
2.72GlnHis: 2.72 ± 0.854
0.0GlnIle: 0.0 ± 0.0
1.813GlnLys: 1.813 ± 0.147
8.16GlnLeu: 8.16 ± 3.829
1.813GlnMet: 1.813 ± 0.147
1.813GlnAsn: 1.813 ± 1.414
2.72GlnPro: 2.72 ± 2.121
0.907GlnGln: 0.907 ± 0.707
1.813GlnArg: 1.813 ± 0.147
1.813GlnSer: 1.813 ± 0.147
0.0GlnThr: 0.0 ± 0.0
1.813GlnVal: 1.813 ± 1.414
0.0GlnTrp: 0.0 ± 0.0
3.626GlnTyr: 3.626 ± 1.561
0.0GlnXaa: 0.0 ± 0.0
Arg
3.626ArgAla: 3.626 ± 0.294
0.907ArgCys: 0.907 ± 0.56
4.533ArgAsp: 4.533 ± 2.799
0.907ArgGlu: 0.907 ± 0.707
4.533ArgPhe: 4.533 ± 1.001
0.907ArgGly: 0.907 ± 0.707
1.813ArgHis: 1.813 ± 1.12
3.626ArgIle: 3.626 ± 0.294
0.907ArgLys: 0.907 ± 0.56
4.533ArgLeu: 4.533 ± 1.001
1.813ArgMet: 1.813 ± 1.12
3.626ArgAsn: 3.626 ± 0.294
2.72ArgPro: 2.72 ± 1.68
0.0ArgGln: 0.0 ± 0.0
6.346ArgArg: 6.346 ± 2.652
3.626ArgSer: 3.626 ± 0.294
6.346ArgThr: 6.346 ± 1.148
2.72ArgVal: 2.72 ± 0.413
0.907ArgTrp: 0.907 ± 0.56
2.72ArgTyr: 2.72 ± 0.413
0.0ArgXaa: 0.0 ± 0.0
Ser
5.44SerAla: 5.44 ± 1.708
0.907SerCys: 0.907 ± 0.56
0.907SerAsp: 0.907 ± 0.56
1.813SerGlu: 1.813 ± 1.12
3.626SerPhe: 3.626 ± 1.561
6.346SerGly: 6.346 ± 1.386
0.907SerHis: 0.907 ± 0.56
5.44SerIle: 5.44 ± 0.441
0.907SerLys: 0.907 ± 0.707
5.44SerLeu: 5.44 ± 1.708
1.813SerMet: 1.813 ± 0.147
0.0SerAsn: 0.0 ± 0.0
2.72SerPro: 2.72 ± 0.854
3.626SerGln: 3.626 ± 1.561
2.72SerArg: 2.72 ± 0.854
4.533SerSer: 4.533 ± 3.535
5.44SerThr: 5.44 ± 1.708
1.813SerVal: 1.813 ± 1.414
1.813SerTrp: 1.813 ± 1.12
2.72SerTyr: 2.72 ± 0.854
0.0SerXaa: 0.0 ± 0.0
Thr
3.626ThrAla: 3.626 ± 0.973
0.907ThrCys: 0.907 ± 0.56
2.72ThrAsp: 2.72 ± 0.854
4.533ThrGlu: 4.533 ± 1.001
7.253ThrPhe: 7.253 ± 0.679
5.44ThrGly: 5.44 ± 0.441
3.626ThrHis: 3.626 ± 0.973
3.626ThrIle: 3.626 ± 0.973
2.72ThrLys: 2.72 ± 1.68
7.253ThrLeu: 7.253 ± 3.212
4.533ThrMet: 4.533 ± 1.533
4.533ThrAsn: 4.533 ± 2.268
9.066ThrPro: 9.066 ± 2.002
3.626ThrGln: 3.626 ± 1.561
2.72ThrArg: 2.72 ± 0.854
2.72ThrSer: 2.72 ± 0.854
4.533ThrThr: 4.533 ± 0.266
2.72ThrVal: 2.72 ± 0.854
1.813ThrTrp: 1.813 ± 0.147
1.813ThrTyr: 1.813 ± 0.147
0.0ThrXaa: 0.0 ± 0.0
Val
4.533ValAla: 4.533 ± 2.268
0.0ValCys: 0.0 ± 0.0
1.813ValAsp: 1.813 ± 0.147
0.907ValGlu: 0.907 ± 0.56
1.813ValPhe: 1.813 ± 1.12
0.0ValGly: 0.0 ± 0.0
2.72ValHis: 2.72 ± 2.121
0.907ValIle: 0.907 ± 0.56
2.72ValLys: 2.72 ± 1.68
2.72ValLeu: 2.72 ± 0.413
1.813ValMet: 1.813 ± 1.111
2.72ValAsn: 2.72 ± 0.413
5.44ValPro: 5.44 ± 1.708
1.813ValGln: 1.813 ± 1.12
1.813ValArg: 1.813 ± 1.414
0.907ValSer: 0.907 ± 0.707
2.72ValThr: 2.72 ± 0.854
0.907ValVal: 0.907 ± 0.56
0.0ValTrp: 0.0 ± 0.0
0.907ValTyr: 0.907 ± 0.707
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.907TrpGlu: 0.907 ± 0.56
3.626TrpPhe: 3.626 ± 0.294
1.813TrpGly: 1.813 ± 1.12
0.907TrpHis: 0.907 ± 0.56
3.626TrpIle: 3.626 ± 0.973
0.0TrpLys: 0.0 ± 0.0
1.813TrpLeu: 1.813 ± 0.147
0.907TrpMet: 0.907 ± 0.707
2.72TrpAsn: 2.72 ± 0.413
0.907TrpPro: 0.907 ± 0.56
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
3.626TrpSer: 3.626 ± 1.561
2.72TrpThr: 2.72 ± 0.413
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.813TrpTyr: 1.813 ± 0.147
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.533TyrAla: 4.533 ± 1.001
1.813TyrCys: 1.813 ± 0.147
0.907TyrAsp: 0.907 ± 0.56
0.907TyrGlu: 0.907 ± 0.56
4.533TyrPhe: 4.533 ± 0.266
0.907TyrGly: 0.907 ± 0.707
1.813TyrHis: 1.813 ± 0.147
2.72TyrIle: 2.72 ± 0.413
2.72TyrLys: 2.72 ± 1.68
4.533TyrLeu: 4.533 ± 2.799
0.0TyrMet: 0.0 ± 0.0
2.72TyrAsn: 2.72 ± 1.68
5.44TyrPro: 5.44 ± 2.975
0.0TyrGln: 0.0 ± 0.0
4.533TyrArg: 4.533 ± 1.533
1.813TyrSer: 1.813 ± 0.147
1.813TyrThr: 1.813 ± 1.12
1.813TyrVal: 1.813 ± 0.147
1.813TyrTrp: 1.813 ± 0.147
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski