Corynebacterium geronticis
Average proteome isoelectric point is 6.08
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 2094 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A3G6IYW9|A0A3G6IYW9_9CORY Transcriptional regulator LytR OS=Corynebacterium geronticis OX=2079234 GN=lytR PE=3 SV=1
MM1 pKa = 7.92 LYY3 pKa = 10.04 TIDD6 pKa = 3.96 GASLVDD12 pKa = 3.44 QGQWEE17 pKa = 4.59 YY18 pKa = 10.28 TAGPSGTPEE27 pKa = 3.85 SLEE30 pKa = 3.92 AAEE33 pKa = 6.4 AEE35 pKa = 4.23 LDD37 pKa = 3.6 WEE39 pKa = 4.85 NIAQRR44 pKa = 11.84 PFNEE48 pKa = 4.08 QPDD51 pKa = 4.27 LLRR54 pKa = 11.84 SNPGDD59 pKa = 3.46 LPNIEE64 pKa = 4.9 GEE66 pKa = 4.41 TGGQDD71 pKa = 2.96 AASAKK76 pKa = 10.44 SEE78 pKa = 4.08 EE79 pKa = 4.37 KK80 pKa = 9.95 TSNRR84 pKa = 11.84 SIEE87 pKa = 4.11 DD88 pKa = 3.53 VVDD91 pKa = 3.97 GRR93 pKa = 11.84 SKK95 pKa = 11.63 ADD97 pKa = 3.53 FPTFSGDD104 pKa = 3.42 ASSANPNYY112 pKa = 9.99 VPKK115 pKa = 10.27 TSPQFARR122 pKa = 11.84 AVYY125 pKa = 10.11 NAFILEE131 pKa = 4.76 WIYY134 pKa = 11.23 NANTTPVLEE143 pKa = 4.39 VASPVTGQTYY153 pKa = 9.04 TMTCVQNTSVTCRR166 pKa = 11.84 GGNDD170 pKa = 3.05 AVVYY174 pKa = 9.65 IYY176 pKa = 10.13 PPSPYY181 pKa = 10.2 APPDD185 pKa = 3.59 GVQWGG190 pKa = 3.56
Molecular weight: 20.46 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.795
IPC2_protein 3.999
IPC_protein 3.948
Toseland 3.757
ProMoST 4.088
Dawson 3.91
Bjellqvist 4.062
Wikipedia 3.808
Rodwell 3.77
Grimsley 3.668
Solomon 3.897
Lehninger 3.859
Nozaki 4.024
DTASelect 4.202
Thurlkill 3.795
EMBOSS 3.834
Sillero 4.062
Patrickios 1.901
IPC_peptide 3.91
IPC2_peptide 4.037
IPC2.peptide.svr19 3.929
Protein with the highest isoelectric point:
>tr|A0A3G6IX58|A0A3G6IX58_9CORY Uncharacterized protein OS=Corynebacterium geronticis OX=2079234 GN=CGERO_00020 PE=4 SV=1
MM1 pKa = 7.69 AKK3 pKa = 10.06 GKK5 pKa = 8.69 RR6 pKa = 11.84 TFQPNNRR13 pKa = 11.84 RR14 pKa = 11.84 RR15 pKa = 11.84 ARR17 pKa = 11.84 KK18 pKa = 8.59 HH19 pKa = 4.58 GFRR22 pKa = 11.84 TRR24 pKa = 11.84 MRR26 pKa = 11.84 TRR28 pKa = 11.84 AGRR31 pKa = 11.84 AIVAARR37 pKa = 11.84 RR38 pKa = 11.84 QKK40 pKa = 10.58 GRR42 pKa = 11.84 AKK44 pKa = 9.64 LTAA47 pKa = 4.21
Molecular weight: 5.49 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.526
IPC2_protein 11.316
IPC_protein 12.925
Toseland 13.086
ProMoST 13.583
Dawson 13.086
Bjellqvist 13.086
Wikipedia 13.568
Rodwell 12.735
Grimsley 13.13
Solomon 13.583
Lehninger 13.481
Nozaki 13.086
DTASelect 13.086
Thurlkill 13.086
EMBOSS 13.583
Sillero 13.086
Patrickios 12.457
IPC_peptide 13.583
IPC2_peptide 12.574
IPC2.peptide.svr19 9.237
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
2094
0
2094
684442
29
3012
326.9
35.55
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
11.605 ± 0.068
0.809 ± 0.017
5.568 ± 0.04
6.586 ± 0.06
3.431 ± 0.035
8.134 ± 0.038
2.342 ± 0.026
5.115 ± 0.036
3.494 ± 0.04
9.876 ± 0.057
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.361 ± 0.021
2.88 ± 0.027
4.943 ± 0.037
3.929 ± 0.03
6.141 ± 0.046
5.757 ± 0.033
5.402 ± 0.034
8.115 ± 0.041
1.384 ± 0.021
2.13 ± 0.026
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here