Amino acid dipepetide frequency for Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) (Flexibacter canadensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.457AlaAla: 5.457 ± 0.097
0.678AlaCys: 0.678 ± 0.024
3.879AlaAsp: 3.879 ± 0.062
4.27AlaGlu: 4.27 ± 0.062
3.365AlaPhe: 3.365 ± 0.053
5.122AlaGly: 5.122 ± 0.105
1.074AlaHis: 1.074 ± 0.03
5.441AlaIle: 5.441 ± 0.072
4.769AlaLys: 4.769 ± 0.069
6.359AlaLeu: 6.359 ± 0.076
1.557AlaMet: 1.557 ± 0.036
3.768AlaAsn: 3.768 ± 0.064
2.29AlaPro: 2.29 ± 0.079
2.706AlaGln: 2.706 ± 0.045
2.178AlaArg: 2.178 ± 0.047
4.598AlaSer: 4.598 ± 0.085
4.203AlaThr: 4.203 ± 0.116
4.579AlaVal: 4.579 ± 0.064
0.689AlaTrp: 0.689 ± 0.025
2.676AlaTyr: 2.676 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.507CysAla: 0.507 ± 0.022
0.141CysCys: 0.141 ± 0.01
0.427CysAsp: 0.427 ± 0.018
0.462CysGlu: 0.462 ± 0.03
0.476CysPhe: 0.476 ± 0.019
0.636CysGly: 0.636 ± 0.024
0.173CysHis: 0.173 ± 0.012
0.596CysIle: 0.596 ± 0.018
0.545CysLys: 0.545 ± 0.022
0.772CysLeu: 0.772 ± 0.024
0.18CysMet: 0.18 ± 0.011
0.451CysAsn: 0.451 ± 0.025
0.357CysPro: 0.357 ± 0.017
0.248CysGln: 0.248 ± 0.015
0.27CysArg: 0.27 ± 0.013
0.623CysSer: 0.623 ± 0.027
0.485CysThr: 0.485 ± 0.026
0.471CysVal: 0.471 ± 0.028
0.097CysTrp: 0.097 ± 0.007
0.343CysTyr: 0.343 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
3.721AspAla: 3.721 ± 0.062
0.391AspCys: 0.391 ± 0.018
2.554AspAsp: 2.554 ± 0.051
3.47AspGlu: 3.47 ± 0.061
3.129AspPhe: 3.129 ± 0.048
3.611AspGly: 3.611 ± 0.071
0.956AspHis: 0.956 ± 0.025
3.821AspIle: 3.821 ± 0.054
4.085AspLys: 4.085 ± 0.062
4.892AspLeu: 4.892 ± 0.062
1.083AspMet: 1.083 ± 0.03
2.937AspAsn: 2.937 ± 0.047
2.091AspPro: 2.091 ± 0.044
1.835AspGln: 1.835 ± 0.035
2.079AspArg: 2.079 ± 0.046
3.032AspSer: 3.032 ± 0.056
2.427AspThr: 2.427 ± 0.047
3.422AspVal: 3.422 ± 0.057
0.742AspTrp: 0.742 ± 0.022
2.621AspTyr: 2.621 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
4.062GluAla: 4.062 ± 0.059
0.377GluCys: 0.377 ± 0.017
2.678GluAsp: 2.678 ± 0.057
3.989GluGlu: 3.989 ± 0.07
2.65GluPhe: 2.65 ± 0.053
3.511GluGly: 3.511 ± 0.06
1.11GluHis: 1.11 ± 0.032
4.537GluIle: 4.537 ± 0.068
5.159GluLys: 5.159 ± 0.083
6.117GluLeu: 6.117 ± 0.08
1.536GluMet: 1.536 ± 0.033
3.666GluAsn: 3.666 ± 0.048
1.619GluPro: 1.619 ± 0.037
2.474GluGln: 2.474 ± 0.051
2.522GluArg: 2.522 ± 0.05
3.261GluSer: 3.261 ± 0.049
3.113GluThr: 3.113 ± 0.05
3.928GluVal: 3.928 ± 0.055
0.705GluTrp: 0.705 ± 0.022
2.3GluTyr: 2.3 ± 0.049
0.0GluXaa: 0.0 ± 0.0
Phe
3.202PheAla: 3.202 ± 0.055
0.476PheCys: 0.476 ± 0.023
2.995PheAsp: 2.995 ± 0.039
2.912PheGlu: 2.912 ± 0.056
2.545PhePhe: 2.545 ± 0.053
3.384PheGly: 3.384 ± 0.054
0.8PheHis: 0.8 ± 0.025
3.709PheIle: 3.709 ± 0.056
3.394PheLys: 3.394 ± 0.048
4.353PheLeu: 4.353 ± 0.072
1.188PheMet: 1.188 ± 0.031
3.137PheAsn: 3.137 ± 0.054
1.732PhePro: 1.732 ± 0.035
1.418PheGln: 1.418 ± 0.031
1.735PheArg: 1.735 ± 0.041
3.834PheSer: 3.834 ± 0.054
3.144PheThr: 3.144 ± 0.064
2.994PheVal: 2.994 ± 0.053
0.6PheTrp: 0.6 ± 0.022
2.147PheTyr: 2.147 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
4.523GlyAla: 4.523 ± 0.076
0.711GlyCys: 0.711 ± 0.053
3.232GlyAsp: 3.232 ± 0.054
3.42GlyGlu: 3.42 ± 0.05
3.638GlyPhe: 3.638 ± 0.055
4.798GlyGly: 4.798 ± 0.094
1.081GlyHis: 1.081 ± 0.028
5.15GlyIle: 5.15 ± 0.071
5.169GlyLys: 5.169 ± 0.069
6.046GlyLeu: 6.046 ± 0.076
1.595GlyMet: 1.595 ± 0.029
3.897GlyAsn: 3.897 ± 0.07
1.615GlyPro: 1.615 ± 0.052
2.202GlyGln: 2.202 ± 0.051
2.327GlyArg: 2.327 ± 0.049
4.494GlySer: 4.494 ± 0.072
4.452GlyThr: 4.452 ± 0.119
4.661GlyVal: 4.661 ± 0.064
0.917GlyTrp: 0.917 ± 0.027
3.046GlyTyr: 3.046 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
0.946HisAla: 0.946 ± 0.027
0.184HisCys: 0.184 ± 0.011
0.774HisAsp: 0.774 ± 0.026
0.974HisGlu: 0.974 ± 0.025
1.068HisPhe: 1.068 ± 0.031
1.027HisGly: 1.027 ± 0.031
0.487HisHis: 0.487 ± 0.019
1.222HisIle: 1.222 ± 0.03
1.074HisLys: 1.074 ± 0.029
1.808HisLeu: 1.808 ± 0.038
0.358HisMet: 0.358 ± 0.015
0.869HisAsn: 0.869 ± 0.026
0.907HisPro: 0.907 ± 0.024
0.671HisGln: 0.671 ± 0.023
0.661HisArg: 0.661 ± 0.018
1.055HisSer: 1.055 ± 0.031
0.956HisThr: 0.956 ± 0.025
0.918HisVal: 0.918 ± 0.028
0.229HisTrp: 0.229 ± 0.014
0.877HisTyr: 0.877 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.738IleAla: 5.738 ± 0.077
0.709IleCys: 0.709 ± 0.025
4.575IleAsp: 4.575 ± 0.06
4.658IleGlu: 4.658 ± 0.078
2.932IlePhe: 2.932 ± 0.054
4.992IleGly: 4.992 ± 0.076
1.28IleHis: 1.28 ± 0.03
5.462IleIle: 5.462 ± 0.08
5.421IleLys: 5.421 ± 0.061
5.953IleLeu: 5.953 ± 0.085
1.339IleMet: 1.339 ± 0.037
4.727IleAsn: 4.727 ± 0.056
3.102IlePro: 3.102 ± 0.047
2.33IleGln: 2.33 ± 0.04
2.686IleArg: 2.686 ± 0.048
5.313IleSer: 5.313 ± 0.068
4.887IleThr: 4.887 ± 0.085
4.555IleVal: 4.555 ± 0.065
0.689IleTrp: 0.689 ± 0.022
2.723IleTyr: 2.723 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
5.123LysAla: 5.123 ± 0.073
0.4LysCys: 0.4 ± 0.018
4.106LysAsp: 4.106 ± 0.063
5.306LysGlu: 5.306 ± 0.092
2.886LysPhe: 2.886 ± 0.047
4.746LysGly: 4.746 ± 0.066
1.297LysHis: 1.297 ± 0.033
5.307LysIle: 5.307 ± 0.067
5.765LysLys: 5.765 ± 0.079
6.584LysLeu: 6.584 ± 0.08
1.937LysMet: 1.937 ± 0.041
4.582LysAsn: 4.582 ± 0.063
2.571LysPro: 2.571 ± 0.04
2.846LysGln: 2.846 ± 0.054
2.803LysArg: 2.803 ± 0.052
4.343LysSer: 4.343 ± 0.066
4.376LysThr: 4.376 ± 0.055
4.857LysVal: 4.857 ± 0.061
0.89LysTrp: 0.89 ± 0.027
2.973LysTyr: 2.973 ± 0.044
0.0LysXaa: 0.0 ± 0.0
Leu
6.26LeuAla: 6.26 ± 0.078
0.741LeuCys: 0.741 ± 0.023
4.366LeuAsp: 4.366 ± 0.06
4.853LeuGlu: 4.853 ± 0.071
4.735LeuPhe: 4.735 ± 0.074
5.714LeuGly: 5.714 ± 0.082
1.605LeuHis: 1.605 ± 0.034
6.856LeuIle: 6.856 ± 0.092
7.458LeuLys: 7.458 ± 0.09
9.229LeuLeu: 9.229 ± 0.127
2.208LeuMet: 2.208 ± 0.042
5.583LeuAsn: 5.583 ± 0.066
3.793LeuPro: 3.793 ± 0.047
3.314LeuGln: 3.314 ± 0.05
3.428LeuArg: 3.428 ± 0.061
7.172LeuSer: 7.172 ± 0.072
5.928LeuThr: 5.928 ± 0.084
5.396LeuVal: 5.396 ± 0.081
0.903LeuTrp: 0.903 ± 0.027
3.212LeuTyr: 3.212 ± 0.055
0.0LeuXaa: 0.0 ± 0.0
Met
1.613MetAla: 1.613 ± 0.035
0.138MetCys: 0.138 ± 0.01
1.168MetAsp: 1.168 ± 0.032
1.302MetGlu: 1.302 ± 0.033
0.828MetPhe: 0.828 ± 0.025
1.502MetGly: 1.502 ± 0.034
0.43MetHis: 0.43 ± 0.019
1.63MetIle: 1.63 ± 0.036
2.164MetLys: 2.164 ± 0.034
2.045MetLeu: 2.045 ± 0.047
0.59MetMet: 0.59 ± 0.022
1.43MetAsn: 1.43 ± 0.033
0.964MetPro: 0.964 ± 0.025
0.889MetGln: 0.889 ± 0.027
0.932MetArg: 0.932 ± 0.021
1.353MetSer: 1.353 ± 0.033
1.087MetThr: 1.087 ± 0.026
1.397MetVal: 1.397 ± 0.034
0.174MetTrp: 0.174 ± 0.01
0.715MetTyr: 0.715 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
4.135AsnAla: 4.135 ± 0.064
0.467AsnCys: 0.467 ± 0.021
3.187AsnAsp: 3.187 ± 0.058
3.638AsnGlu: 3.638 ± 0.05
2.742AsnPhe: 2.742 ± 0.052
4.452AsnGly: 4.452 ± 0.089
0.964AsnHis: 0.964 ± 0.027
4.124AsnIle: 4.124 ± 0.058
4.094AsnLys: 4.094 ± 0.065
4.992AsnLeu: 4.992 ± 0.068
1.259AsnMet: 1.259 ± 0.03
3.779AsnAsn: 3.779 ± 0.069
2.7AsnPro: 2.7 ± 0.072
2.118AsnGln: 2.118 ± 0.043
2.263AsnArg: 2.263 ± 0.046
3.795AsnSer: 3.795 ± 0.055
3.401AsnThr: 3.401 ± 0.065
3.573AsnVal: 3.573 ± 0.057
0.799AsnTrp: 0.799 ± 0.026
3.032AsnTyr: 3.032 ± 0.058
0.0AsnXaa: 0.0 ± 0.0
Pro
2.693ProAla: 2.693 ± 0.061
0.239ProCys: 0.239 ± 0.013
2.367ProAsp: 2.367 ± 0.043
2.667ProGlu: 2.667 ± 0.05
1.872ProPhe: 1.872 ± 0.039
2.465ProGly: 2.465 ± 0.051
0.618ProHis: 0.618 ± 0.022
2.548ProIle: 2.548 ± 0.042
2.212ProLys: 2.212 ± 0.04
3.21ProLeu: 3.21 ± 0.045
0.74ProMet: 0.74 ± 0.023
2.01ProAsn: 2.01 ± 0.042
0.979ProPro: 0.979 ± 0.029
1.403ProGln: 1.403 ± 0.032
0.989ProArg: 0.989 ± 0.033
2.398ProSer: 2.398 ± 0.05
2.186ProThr: 2.186 ± 0.084
3.076ProVal: 3.076 ± 0.065
0.36ProTrp: 0.36 ± 0.018
1.527ProTyr: 1.527 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
2.295GlnAla: 2.295 ± 0.042
0.19GlnCys: 0.19 ± 0.012
1.487GlnAsp: 1.487 ± 0.029
1.96GlnGlu: 1.96 ± 0.042
1.696GlnPhe: 1.696 ± 0.035
1.982GlnGly: 1.982 ± 0.05
0.68GlnHis: 0.68 ± 0.02
2.353GlnIle: 2.353 ± 0.041
2.834GlnLys: 2.834 ± 0.045
4.015GlnLeu: 4.015 ± 0.066
0.873GlnMet: 0.873 ± 0.027
2.084GlnAsn: 2.084 ± 0.045
1.407GlnPro: 1.407 ± 0.035
1.864GlnGln: 1.864 ± 0.047
1.457GlnArg: 1.457 ± 0.032
2.351GlnSer: 2.351 ± 0.044
2.086GlnThr: 2.086 ± 0.046
2.127GlnVal: 2.127 ± 0.04
0.472GlnTrp: 0.472 ± 0.026
1.563GlnTyr: 1.563 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
2.105ArgAla: 2.105 ± 0.039
0.24ArgCys: 0.24 ± 0.012
1.76ArgAsp: 1.76 ± 0.04
2.134ArgGlu: 2.134 ± 0.036
2.179ArgPhe: 2.179 ± 0.043
1.937ArgGly: 1.937 ± 0.042
0.604ArgHis: 0.604 ± 0.022
3.042ArgIle: 3.042 ± 0.05
2.882ArgLys: 2.882 ± 0.057
3.501ArgLeu: 3.501 ± 0.054
0.952ArgMet: 0.952 ± 0.027
2.196ArgAsn: 2.196 ± 0.043
1.234ArgPro: 1.234 ± 0.03
1.252ArgGln: 1.252 ± 0.032
1.401ArgArg: 1.401 ± 0.038
2.268ArgSer: 2.268 ± 0.042
1.961ArgThr: 1.961 ± 0.034
2.311ArgVal: 2.311 ± 0.046
0.491ArgTrp: 0.491 ± 0.019
1.62ArgTyr: 1.62 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
4.729SerAla: 4.729 ± 0.066
0.676SerCys: 0.676 ± 0.028
3.325SerAsp: 3.325 ± 0.047
3.311SerGlu: 3.311 ± 0.048
4.031SerPhe: 4.031 ± 0.055
4.974SerGly: 4.974 ± 0.081
1.033SerHis: 1.033 ± 0.025
5.268SerIle: 5.268 ± 0.066
4.396SerLys: 4.396 ± 0.062
6.378SerLeu: 6.378 ± 0.07
1.387SerMet: 1.387 ± 0.033
3.562SerAsn: 3.562 ± 0.059
2.311SerPro: 2.311 ± 0.04
2.104SerGln: 2.104 ± 0.038
2.2SerArg: 2.2 ± 0.039
4.66SerSer: 4.66 ± 0.076
4.121SerThr: 4.121 ± 0.088
4.563SerVal: 4.563 ± 0.064
0.828SerTrp: 0.828 ± 0.029
2.983SerTyr: 2.983 ± 0.054
0.0SerXaa: 0.0 ± 0.0
Thr
4.479ThrAla: 4.479 ± 0.1
0.389ThrCys: 0.389 ± 0.028
3.369ThrAsp: 3.369 ± 0.059
3.284ThrGlu: 3.284 ± 0.046
2.837ThrPhe: 2.837 ± 0.054
4.608ThrGly: 4.608 ± 0.106
0.944ThrHis: 0.944 ± 0.027
4.83ThrIle: 4.83 ± 0.083
3.551ThrLys: 3.551 ± 0.056
5.443ThrLeu: 5.443 ± 0.066
1.017ThrMet: 1.017 ± 0.028
3.317ThrAsn: 3.317 ± 0.067
2.706ThrPro: 2.706 ± 0.083
1.947ThrGln: 1.947 ± 0.046
1.748ThrArg: 1.748 ± 0.04
3.887ThrSer: 3.887 ± 0.075
3.849ThrThr: 3.849 ± 0.109
4.468ThrVal: 4.468 ± 0.151
0.632ThrTrp: 0.632 ± 0.026
2.601ThrTyr: 2.601 ± 0.08
0.0ThrXaa: 0.0 ± 0.0
Val
4.602ValAla: 4.602 ± 0.073
0.616ValCys: 0.616 ± 0.029
3.534ValAsp: 3.534 ± 0.052
3.718ValGlu: 3.718 ± 0.053
3.242ValPhe: 3.242 ± 0.052
3.944ValGly: 3.944 ± 0.053
0.958ValHis: 0.958 ± 0.025
4.882ValIle: 4.882 ± 0.063
4.839ValLys: 4.839 ± 0.054
5.975ValLeu: 5.975 ± 0.08
1.409ValMet: 1.409 ± 0.034
4.071ValAsn: 4.071 ± 0.069
2.267ValPro: 2.267 ± 0.044
2.041ValGln: 2.041 ± 0.041
2.257ValArg: 2.257 ± 0.038
4.623ValSer: 4.623 ± 0.067
4.014ValThr: 4.014 ± 0.124
4.535ValVal: 4.535 ± 0.071
0.69ValTrp: 0.69 ± 0.021
2.609ValTyr: 2.609 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.737TrpAla: 0.737 ± 0.03
0.12TrpCys: 0.12 ± 0.01
0.642TrpAsp: 0.642 ± 0.021
0.662TrpGlu: 0.662 ± 0.022
0.57TrpPhe: 0.57 ± 0.021
0.845TrpGly: 0.845 ± 0.028
0.213TrpHis: 0.213 ± 0.011
0.788TrpIle: 0.788 ± 0.025
0.869TrpLys: 0.869 ± 0.025
1.152TrpLeu: 1.152 ± 0.033
0.347TrpMet: 0.347 ± 0.018
0.722TrpAsn: 0.722 ± 0.024
0.28TrpPro: 0.28 ± 0.014
0.471TrpGln: 0.471 ± 0.019
0.428TrpArg: 0.428 ± 0.017
0.723TrpSer: 0.723 ± 0.02
0.651TrpThr: 0.651 ± 0.025
0.748TrpVal: 0.748 ± 0.026
0.186TrpTrp: 0.186 ± 0.012
0.487TrpTyr: 0.487 ± 0.031
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.732TyrAla: 2.732 ± 0.05
0.377TyrCys: 0.377 ± 0.015
2.475TyrAsp: 2.475 ± 0.059
2.324TyrGlu: 2.324 ± 0.044
2.277TyrPhe: 2.277 ± 0.053
2.727TyrGly: 2.727 ± 0.051
0.76TyrHis: 0.76 ± 0.026
2.502TyrIle: 2.502 ± 0.045
3.021TyrLys: 3.021 ± 0.048
3.924TyrLeu: 3.924 ± 0.059
0.794TyrMet: 0.794 ± 0.024
2.726TyrAsn: 2.726 ± 0.051
1.633TyrPro: 1.633 ± 0.032
1.644TyrGln: 1.644 ± 0.043
1.704TyrArg: 1.704 ± 0.038
3.06TyrSer: 3.06 ± 0.05
2.578TyrThr: 2.578 ± 0.069
2.247TyrVal: 2.247 ± 0.042
0.549TyrTrp: 0.549 ± 0.02
2.067TyrTyr: 2.067 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4304 proteins (1505703 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski