Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) (HBV-C)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Blubervirales; Hepadnaviridae; Orthohepadnavirus; Hepatitis B virus; HBV genotype C

Average proteome isoelectric point is 8.42

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q69028|DPOL_HBVCJ Protein P OS=Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) OX=928302 GN=P PE=3 SV=2
MM1 pKa = 7.82AARR4 pKa = 11.84LCCQLDD10 pKa = 3.48PARR13 pKa = 11.84DD14 pKa = 3.92VLCLRR19 pKa = 11.84PVGAEE24 pKa = 3.62SRR26 pKa = 11.84GRR28 pKa = 11.84PVSGPFGPLPSPSSSAVPADD48 pKa = 3.73HH49 pKa = 6.87GAHH52 pKa = 6.43LSLRR56 pKa = 11.84GLPVCAFSSAGPCALRR72 pKa = 11.84FTSARR77 pKa = 11.84SMEE80 pKa = 4.41TTVNAHH86 pKa = 4.75QVLPKK91 pKa = 10.12VLHH94 pKa = 6.14KK95 pKa = 10.13RR96 pKa = 11.84TLGLSAMSTTDD107 pKa = 3.32LEE109 pKa = 5.55AYY111 pKa = 10.39FKK113 pKa = 11.19DD114 pKa = 4.14CLFKK118 pKa = 10.77DD119 pKa = 3.51WEE121 pKa = 4.27EE122 pKa = 3.98LGEE125 pKa = 4.19EE126 pKa = 3.71IRR128 pKa = 11.84LKK130 pKa = 11.04VFVLGGCRR138 pKa = 11.84HH139 pKa = 6.36KK140 pKa = 10.73LVCSPAPCNFFPSAA154 pKa = 3.77

Molecular weight: 16.51 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q69027|X_HBVCJ Protein X OS=Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) OX=928302 GN=X PE=1 SV=1
MM1 pKa = 7.3QLFPLCLIISCSCPTVQASKK21 pKa = 11.2LCLGWLWGMDD31 pKa = 2.87IDD33 pKa = 4.46PYY35 pKa = 11.3KK36 pKa = 10.83EE37 pKa = 4.0FGASVEE43 pKa = 4.32LLSFLPSDD51 pKa = 4.29FFPSIRR57 pKa = 11.84DD58 pKa = 3.75LLDD61 pKa = 3.44TASALYY67 pKa = 10.4RR68 pKa = 11.84EE69 pKa = 4.55ALEE72 pKa = 4.62SPEE75 pKa = 4.18HH76 pKa = 6.65CSPHH80 pKa = 5.29HH81 pKa = 5.26TALRR85 pKa = 11.84QAILCWGEE93 pKa = 4.13LMNLATWVGSNLEE106 pKa = 4.4DD107 pKa = 3.67PASRR111 pKa = 11.84EE112 pKa = 4.06LVVSYY117 pKa = 11.29VNVNMGLKK125 pKa = 9.51IRR127 pKa = 11.84QLLWFHH133 pKa = 6.76ISCLTFGRR141 pKa = 11.84EE142 pKa = 3.77TVLEE146 pKa = 4.1YY147 pKa = 10.79LVSFGVWIRR156 pKa = 11.84TPPAYY161 pKa = 9.91RR162 pKa = 11.84PPNAPILSTLPEE174 pKa = 4.13TTVVRR179 pKa = 11.84RR180 pKa = 11.84RR181 pKa = 11.84GRR183 pKa = 11.84SPRR186 pKa = 11.84RR187 pKa = 11.84RR188 pKa = 11.84TPSPRR193 pKa = 11.84RR194 pKa = 11.84RR195 pKa = 11.84RR196 pKa = 11.84SQSPRR201 pKa = 11.84RR202 pKa = 11.84RR203 pKa = 11.84RR204 pKa = 11.84SQSRR208 pKa = 11.84EE209 pKa = 4.05SQCC212 pKa = 4.24

Molecular weight: 24.29 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

2

7

2299

154

843

328.4

36.67

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.394 ± 0.486

3.61 ± 0.69

2.61 ± 0.224

2.653 ± 0.581

5.437 ± 0.493

6.525 ± 0.45

2.566 ± 0.772

4.089 ± 0.353

2.131 ± 0.748

12.484 ± 0.518

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.783 ± 0.311

3.262 ± 0.42

9.526 ± 0.908

3.48 ± 0.313

6.438 ± 0.963

10.613 ± 0.153

6.481 ± 0.53

5.133 ± 0.388

3.175 ± 0.588

2.61 ± 0.537
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski