Amino acid dipepetide frequency for Halastavi arva RNA virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.853AlaAla: 8.853 ± 1.721
0.708AlaCys: 0.708 ± 0.4
3.187AlaAsp: 3.187 ± 0.68
5.312AlaGlu: 5.312 ± 1.32
3.541AlaPhe: 3.541 ± 0.32
5.666AlaGly: 5.666 ± 1.841
3.541AlaHis: 3.541 ± 0.32
7.082AlaIle: 7.082 ± 1.2
1.771AlaLys: 1.771 ± 0.12
4.958AlaLeu: 4.958 ± 0.56
3.541AlaMet: 3.541 ± 0.32
3.895AlaAsn: 3.895 ± 0.04
5.312AlaPro: 5.312 ± 1.481
3.541AlaGln: 3.541 ± 0.24
4.249AlaArg: 4.249 ± 1.521
7.082AlaSer: 7.082 ± 2.161
6.374AlaThr: 6.374 ± 0.8
6.02AlaVal: 6.02 ± 1.721
1.771AlaTrp: 1.771 ± 0.44
2.833AlaTyr: 2.833 ± 0.64
0.0AlaXaa: 0.0 ± 0.0
Cys
3.187CysAla: 3.187 ± 0.68
0.0CysCys: 0.0 ± 0.0
0.354CysAsp: 0.354 ± 0.2
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.416CysGly: 1.416 ± 0.8
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.354CysLys: 0.354 ± 0.2
0.708CysLeu: 0.708 ± 0.4
0.354CysMet: 0.354 ± 0.2
0.354CysAsn: 0.354 ± 0.2
0.354CysPro: 0.354 ± 0.2
0.354CysGln: 0.354 ± 0.2
0.708CysArg: 0.708 ± 0.4
0.708CysSer: 0.708 ± 0.4
1.416CysThr: 1.416 ± 0.24
0.708CysVal: 0.708 ± 0.16
0.0CysTrp: 0.0 ± 0.0
1.062CysTyr: 1.062 ± 0.6
0.0CysXaa: 0.0 ± 0.0
Asp
4.249AspAla: 4.249 ± 0.16
1.062AspCys: 1.062 ± 0.04
1.771AspAsp: 1.771 ± 0.44
2.833AspGlu: 2.833 ± 0.08
4.958AspPhe: 4.958 ± 0.0
3.187AspGly: 3.187 ± 0.68
2.125AspHis: 2.125 ± 0.08
5.666AspIle: 5.666 ± 0.16
1.416AspLys: 1.416 ± 0.8
4.249AspLeu: 4.249 ± 0.16
0.708AspMet: 0.708 ± 0.4
1.771AspAsn: 1.771 ± 0.44
3.187AspPro: 3.187 ± 0.44
3.187AspGln: 3.187 ± 1.801
1.771AspArg: 1.771 ± 1.0
2.833AspSer: 2.833 ± 0.64
3.541AspThr: 3.541 ± 2.481
3.541AspVal: 3.541 ± 0.88
0.0AspTrp: 0.0 ± 0.0
2.479AspTyr: 2.479 ± 0.28
0.0AspXaa: 0.0 ± 0.0
Glu
6.02GluAla: 6.02 ± 1.16
0.354GluCys: 0.354 ± 0.2
2.479GluAsp: 2.479 ± 0.84
1.416GluGlu: 1.416 ± 0.24
1.062GluPhe: 1.062 ± 0.04
2.125GluGly: 2.125 ± 0.08
1.416GluHis: 1.416 ± 0.8
1.771GluIle: 1.771 ± 0.44
2.833GluLys: 2.833 ± 1.04
4.603GluLeu: 4.603 ± 0.761
2.479GluMet: 2.479 ± 0.841
1.771GluAsn: 1.771 ± 0.44
2.479GluPro: 2.479 ± 0.28
1.062GluGln: 1.062 ± 0.04
3.187GluArg: 3.187 ± 0.12
3.541GluSer: 3.541 ± 0.24
2.479GluThr: 2.479 ± 0.28
4.603GluVal: 4.603 ± 0.2
0.708GluTrp: 0.708 ± 0.16
1.771GluTyr: 1.771 ± 0.44
0.0GluXaa: 0.0 ± 0.0
Phe
4.249PheAla: 4.249 ± 0.72
1.062PheCys: 1.062 ± 0.04
4.603PheAsp: 4.603 ± 0.2
4.249PheGlu: 4.249 ± 0.16
0.354PhePhe: 0.354 ± 0.2
4.958PheGly: 4.958 ± 0.56
0.708PheHis: 0.708 ± 0.72
3.187PheIle: 3.187 ± 0.68
2.125PheLys: 2.125 ± 0.64
2.479PheLeu: 2.479 ± 0.28
1.062PheMet: 1.062 ± 0.634
1.416PheAsn: 1.416 ± 0.24
3.187PhePro: 3.187 ± 0.12
1.771PheGln: 1.771 ± 0.12
2.479PheArg: 2.479 ± 0.28
4.958PheSer: 4.958 ± 0.56
4.249PheThr: 4.249 ± 0.72
1.416PheVal: 1.416 ± 0.32
0.0PheTrp: 0.0 ± 0.0
1.062PheTyr: 1.062 ± 0.6
0.0PheXaa: 0.0 ± 0.0
Gly
4.249GlyAla: 4.249 ± 1.521
0.0GlyCys: 0.0 ± 0.0
3.187GlyAsp: 3.187 ± 0.12
1.771GlyGlu: 1.771 ± 1.241
2.833GlyPhe: 2.833 ± 0.48
1.416GlyGly: 1.416 ± 0.24
0.708GlyHis: 0.708 ± 0.4
3.187GlyIle: 3.187 ± 1.801
3.895GlyLys: 3.895 ± 0.04
6.728GlyLeu: 6.728 ± 1.0
1.416GlyMet: 1.416 ± 0.24
2.125GlyAsn: 2.125 ± 0.48
1.062GlyPro: 1.062 ± 0.04
2.125GlyGln: 2.125 ± 0.08
2.125GlyArg: 2.125 ± 1.601
3.541GlySer: 3.541 ± 0.24
6.374GlyThr: 6.374 ± 0.881
4.603GlyVal: 4.603 ± 0.36
0.354GlyTrp: 0.354 ± 0.2
1.771GlyTyr: 1.771 ± 0.12
0.0GlyXaa: 0.0 ± 0.0
His
3.187HisAla: 3.187 ± 1.24
0.354HisCys: 0.354 ± 0.2
1.416HisAsp: 1.416 ± 0.32
0.354HisGlu: 0.354 ± 0.2
1.416HisPhe: 1.416 ± 0.24
1.771HisGly: 1.771 ± 1.0
1.062HisHis: 1.062 ± 0.6
0.708HisIle: 0.708 ± 0.16
0.354HisLys: 0.354 ± 0.2
3.187HisLeu: 3.187 ± 0.12
0.0HisMet: 0.0 ± 0.0
1.771HisAsn: 1.771 ± 0.12
2.125HisPro: 2.125 ± 0.64
1.062HisGln: 1.062 ± 0.04
1.771HisArg: 1.771 ± 0.44
2.479HisSer: 2.479 ± 1.401
0.354HisThr: 0.354 ± 0.36
1.771HisVal: 1.771 ± 0.12
0.708HisTrp: 0.708 ± 0.4
1.416HisTyr: 1.416 ± 0.88
0.0HisXaa: 0.0 ± 0.0
Ile
7.082IleAla: 7.082 ± 0.481
1.062IleCys: 1.062 ± 0.6
3.895IleAsp: 3.895 ± 1.08
3.187IleGlu: 3.187 ± 0.68
3.187IlePhe: 3.187 ± 0.12
3.187IleGly: 3.187 ± 0.44
1.062IleHis: 1.062 ± 0.6
4.249IleIle: 4.249 ± 0.72
6.374IleLys: 6.374 ± 1.36
3.895IleLeu: 3.895 ± 2.201
0.354IleMet: 0.354 ± 0.36
3.541IleAsn: 3.541 ± 0.801
3.187IlePro: 3.187 ± 1.001
1.416IleGln: 1.416 ± 0.24
3.541IleArg: 3.541 ± 0.32
2.125IleSer: 2.125 ± 1.041
5.312IleThr: 5.312 ± 0.36
3.187IleVal: 3.187 ± 0.12
0.708IleTrp: 0.708 ± 0.16
2.833IleTyr: 2.833 ± 1.04
0.0IleXaa: 0.0 ± 0.0
Lys
3.187LysAla: 3.187 ± 1.24
0.708LysCys: 0.708 ± 0.16
4.958LysAsp: 4.958 ± 2.241
0.354LysGlu: 0.354 ± 0.2
1.062LysPhe: 1.062 ± 0.6
0.708LysGly: 0.708 ± 0.4
1.416LysHis: 1.416 ± 0.24
2.833LysIle: 2.833 ± 1.04
2.125LysLys: 2.125 ± 1.201
6.02LysLeu: 6.02 ± 0.04
2.125LysMet: 2.125 ± 0.64
2.125LysAsn: 2.125 ± 0.64
1.771LysPro: 1.771 ± 1.0
1.416LysGln: 1.416 ± 0.32
2.833LysArg: 2.833 ± 0.48
2.833LysSer: 2.833 ± 1.04
3.541LysThr: 3.541 ± 1.441
1.416LysVal: 1.416 ± 0.24
0.0LysTrp: 0.0 ± 0.0
2.479LysTyr: 2.479 ± 0.841
0.0LysXaa: 0.0 ± 0.0
Leu
6.728LeuAla: 6.728 ± 2.121
0.354LeuCys: 0.354 ± 0.36
4.603LeuAsp: 4.603 ± 1.321
6.02LeuGlu: 6.02 ± 0.04
3.187LeuPhe: 3.187 ± 1.24
4.249LeuGly: 4.249 ± 0.16
1.771LeuHis: 1.771 ± 1.0
4.958LeuIle: 4.958 ± 0.0
3.187LeuLys: 3.187 ± 1.801
5.666LeuLeu: 5.666 ± 0.96
1.062LeuMet: 1.062 ± 0.6
2.833LeuAsn: 2.833 ± 0.08
4.249LeuPro: 4.249 ± 0.16
1.062LeuGln: 1.062 ± 0.6
4.249LeuArg: 4.249 ± 0.961
8.499LeuSer: 8.499 ± 2.482
7.082LeuThr: 7.082 ± 2.722
6.374LeuVal: 6.374 ± 0.8
1.416LeuTrp: 1.416 ± 0.32
1.416LeuTyr: 1.416 ± 0.8
0.0LeuXaa: 0.0 ± 0.0
Met
2.833MetAla: 2.833 ± 1.201
0.354MetCys: 0.354 ± 0.2
2.125MetAsp: 2.125 ± 0.08
1.771MetGlu: 1.771 ± 0.12
1.771MetPhe: 1.771 ± 0.12
1.416MetGly: 1.416 ± 0.32
0.708MetHis: 0.708 ± 0.4
0.354MetIle: 0.354 ± 0.2
1.771MetLys: 1.771 ± 0.44
1.416MetLeu: 1.416 ± 0.88
0.708MetMet: 0.708 ± 0.16
0.354MetAsn: 0.354 ± 0.2
0.708MetPro: 0.708 ± 0.72
0.708MetGln: 0.708 ± 0.16
0.708MetArg: 0.708 ± 0.4
1.416MetSer: 1.416 ± 0.32
1.416MetThr: 1.416 ± 0.24
1.416MetVal: 1.416 ± 0.24
0.0MetTrp: 0.0 ± 0.0
1.416MetTyr: 1.416 ± 0.24
0.0MetXaa: 0.0 ± 0.0
Asn
3.187AsnAla: 3.187 ± 0.44
1.416AsnCys: 1.416 ± 0.8
1.062AsnAsp: 1.062 ± 0.04
0.354AsnGlu: 0.354 ± 0.36
3.895AsnPhe: 3.895 ± 0.52
1.062AsnGly: 1.062 ± 0.04
1.062AsnHis: 1.062 ± 0.04
2.833AsnIle: 2.833 ± 0.64
2.479AsnLys: 2.479 ± 0.28
2.479AsnLeu: 2.479 ± 1.401
0.354AsnMet: 0.354 ± 0.36
2.479AsnAsn: 2.479 ± 0.28
3.187AsnPro: 3.187 ± 0.12
0.354AsnGln: 0.354 ± 0.2
1.771AsnArg: 1.771 ± 1.0
3.541AsnSer: 3.541 ± 0.801
2.833AsnThr: 2.833 ± 0.48
5.312AsnVal: 5.312 ± 0.76
0.354AsnTrp: 0.354 ± 0.2
2.833AsnTyr: 2.833 ± 1.201
0.0AsnXaa: 0.0 ± 0.0
Pro
3.541ProAla: 3.541 ± 0.88
0.0ProCys: 0.0 ± 0.0
3.895ProAsp: 3.895 ± 0.04
3.541ProGlu: 3.541 ± 1.441
2.125ProPhe: 2.125 ± 0.48
1.771ProGly: 1.771 ± 0.44
2.479ProHis: 2.479 ± 0.28
4.249ProIle: 4.249 ± 0.4
1.771ProLys: 1.771 ± 1.0
5.312ProLeu: 5.312 ± 2.041
1.062ProMet: 1.062 ± 0.04
2.833ProAsn: 2.833 ± 1.201
2.833ProPro: 2.833 ± 0.08
0.0ProGln: 0.0 ± 0.0
2.479ProArg: 2.479 ± 0.841
6.02ProSer: 6.02 ± 2.201
7.082ProThr: 7.082 ± 2.161
4.249ProVal: 4.249 ± 0.4
1.062ProTrp: 1.062 ± 0.04
2.479ProTyr: 2.479 ± 1.401
0.0ProXaa: 0.0 ± 0.0
Gln
1.771GlnAla: 1.771 ± 1.241
0.354GlnCys: 0.354 ± 0.2
1.062GlnAsp: 1.062 ± 0.52
0.354GlnGlu: 0.354 ± 0.36
2.125GlnPhe: 2.125 ± 0.48
1.771GlnGly: 1.771 ± 0.12
1.416GlnHis: 1.416 ± 0.8
1.416GlnIle: 1.416 ± 0.8
0.708GlnLys: 0.708 ± 0.4
2.833GlnLeu: 2.833 ± 0.48
0.0GlnMet: 0.0 ± 0.0
1.416GlnAsn: 1.416 ± 0.32
4.249GlnPro: 4.249 ± 0.961
1.062GlnGln: 1.062 ± 0.52
2.479GlnArg: 2.479 ± 1.401
2.479GlnSer: 2.479 ± 0.84
1.771GlnThr: 1.771 ± 0.68
0.708GlnVal: 0.708 ± 0.4
0.354GlnTrp: 0.354 ± 0.36
1.062GlnTyr: 1.062 ± 1.081
0.0GlnXaa: 0.0 ± 0.0
Arg
4.603ArgAla: 4.603 ± 0.2
1.416ArgCys: 1.416 ± 0.8
1.416ArgAsp: 1.416 ± 0.8
2.479ArgGlu: 2.479 ± 0.28
2.479ArgPhe: 2.479 ± 0.841
2.125ArgGly: 2.125 ± 0.48
1.062ArgHis: 1.062 ± 0.6
5.312ArgIle: 5.312 ± 0.36
3.187ArgLys: 3.187 ± 0.68
4.603ArgLeu: 4.603 ± 0.761
2.125ArgMet: 2.125 ± 0.478
2.833ArgAsn: 2.833 ± 0.08
2.833ArgPro: 2.833 ± 0.64
1.771ArgGln: 1.771 ± 0.68
4.958ArgArg: 4.958 ± 0.56
1.771ArgSer: 1.771 ± 0.44
2.833ArgThr: 2.833 ± 1.601
3.895ArgVal: 3.895 ± 0.52
0.0ArgTrp: 0.0 ± 0.0
1.416ArgTyr: 1.416 ± 0.32
0.0ArgXaa: 0.0 ± 0.0
Ser
6.02SerAla: 6.02 ± 0.04
1.416SerCys: 1.416 ± 0.8
3.187SerAsp: 3.187 ± 1.001
3.895SerGlu: 3.895 ± 1.161
5.666SerPhe: 5.666 ± 0.16
3.541SerGly: 3.541 ± 0.801
1.416SerHis: 1.416 ± 0.32
3.895SerIle: 3.895 ± 0.04
1.771SerLys: 1.771 ± 0.12
5.312SerLeu: 5.312 ± 0.76
1.771SerMet: 1.771 ± 0.12
2.479SerAsn: 2.479 ± 0.28
5.312SerPro: 5.312 ± 0.921
3.187SerGln: 3.187 ± 0.44
2.125SerArg: 2.125 ± 1.041
9.561SerSer: 9.561 ± 4.683
7.436SerThr: 7.436 ± 1.961
4.603SerVal: 4.603 ± 2.441
1.062SerTrp: 1.062 ± 0.52
2.833SerTyr: 2.833 ± 0.08
0.0SerXaa: 0.0 ± 0.0
Thr
7.436ThrAla: 7.436 ± 1.401
0.708ThrCys: 0.708 ± 0.4
4.958ThrAsp: 4.958 ± 0.0
4.603ThrGlu: 4.603 ± 0.92
4.603ThrPhe: 4.603 ± 0.761
6.02ThrGly: 6.02 ± 1.641
2.479ThrHis: 2.479 ± 0.841
4.249ThrIle: 4.249 ± 0.4
2.479ThrLys: 2.479 ± 0.28
5.666ThrLeu: 5.666 ± 1.521
0.708ThrMet: 0.708 ± 0.16
3.895ThrAsn: 3.895 ± 0.52
5.312ThrPro: 5.312 ± 2.041
3.895ThrGln: 3.895 ± 0.6
4.249ThrArg: 4.249 ± 1.28
6.02ThrSer: 6.02 ± 1.641
9.207ThrThr: 9.207 ± 1.521
3.895ThrVal: 3.895 ± 0.04
0.354ThrTrp: 0.354 ± 0.2
3.187ThrTyr: 3.187 ± 0.68
0.0ThrXaa: 0.0 ± 0.0
Val
4.603ValAla: 4.603 ± 0.2
0.354ValCys: 0.354 ± 0.2
2.125ValAsp: 2.125 ± 0.08
3.541ValGlu: 3.541 ± 0.88
3.541ValPhe: 3.541 ± 1.441
3.541ValGly: 3.541 ± 1.441
2.125ValHis: 2.125 ± 1.201
3.895ValIle: 3.895 ± 0.04
2.833ValLys: 2.833 ± 1.601
5.312ValLeu: 5.312 ± 0.36
1.416ValMet: 1.416 ± 0.88
3.541ValAsn: 3.541 ± 0.32
4.958ValPro: 4.958 ± 0.56
0.708ValGln: 0.708 ± 0.72
4.603ValArg: 4.603 ± 0.2
5.666ValSer: 5.666 ± 1.841
5.312ValThr: 5.312 ± 0.76
3.541ValVal: 3.541 ± 0.32
0.708ValTrp: 0.708 ± 0.16
1.062ValTyr: 1.062 ± 0.52
0.0ValXaa: 0.0 ± 0.0
Trp
0.708TrpAla: 0.708 ± 0.72
0.354TrpCys: 0.354 ± 0.2
2.125TrpAsp: 2.125 ± 0.48
0.708TrpGlu: 0.708 ± 0.4
0.0TrpPhe: 0.0 ± 0.0
0.354TrpGly: 0.354 ± 0.36
0.0TrpHis: 0.0 ± 0.0
0.708TrpIle: 0.708 ± 0.4
0.708TrpLys: 0.708 ± 0.4
0.708TrpLeu: 0.708 ± 0.4
0.708TrpMet: 0.708 ± 0.16
0.0TrpAsn: 0.0 ± 0.0
1.416TrpPro: 1.416 ± 1.441
0.0TrpGln: 0.0 ± 0.0
0.354TrpArg: 0.354 ± 0.2
0.354TrpSer: 0.354 ± 0.2
1.416TrpThr: 1.416 ± 0.32
0.354TrpVal: 0.354 ± 0.2
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.541TyrAla: 3.541 ± 0.801
0.0TyrCys: 0.0 ± 0.0
2.125TyrAsp: 2.125 ± 0.08
1.416TyrGlu: 1.416 ± 0.8
1.771TyrPhe: 1.771 ± 0.68
3.187TyrGly: 3.187 ± 0.12
0.708TyrHis: 0.708 ± 0.16
2.833TyrIle: 2.833 ± 0.64
1.771TyrLys: 1.771 ± 0.44
2.833TyrLeu: 2.833 ± 0.64
1.062TyrMet: 1.062 ± 0.52
1.416TyrAsn: 1.416 ± 0.88
1.062TyrPro: 1.062 ± 0.04
0.708TyrGln: 0.708 ± 0.72
2.833TyrArg: 2.833 ± 0.08
1.062TyrSer: 1.062 ± 0.04
3.895TyrThr: 3.895 ± 1.641
1.771TyrVal: 1.771 ± 0.12
1.416TyrTrp: 1.416 ± 0.88
1.771TyrTyr: 1.771 ± 0.12
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2825 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski