Amino acid dipepetide frequency for Lettuce necrotic yellows virus (isolate 318) (LNYV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.149AlaAla: 4.149 ± 2.276
1.297AlaCys: 1.297 ± 0.29
3.631AlaAsp: 3.631 ± 0.933
2.075AlaGlu: 2.075 ± 0.629
1.297AlaPhe: 1.297 ± 0.554
4.149AlaGly: 4.149 ± 2.063
1.037AlaHis: 1.037 ± 0.618
4.927AlaIle: 4.927 ± 0.526
4.668AlaLys: 4.668 ± 0.476
4.409AlaLeu: 4.409 ± 0.98
2.075AlaMet: 2.075 ± 0.848
1.815AlaAsn: 1.815 ± 1.25
1.556AlaPro: 1.556 ± 0.572
2.075AlaGln: 2.075 ± 0.727
2.334AlaArg: 2.334 ± 1.012
3.631AlaSer: 3.631 ± 1.562
3.89AlaThr: 3.89 ± 1.699
4.149AlaVal: 4.149 ± 1.382
0.259AlaTrp: 0.259 ± 0.286
2.593AlaTyr: 2.593 ± 0.92
0.0AlaXaa: 0.0 ± 0.0
Cys
0.519CysAla: 0.519 ± 0.331
0.519CysCys: 0.519 ± 0.309
1.037CysAsp: 1.037 ± 0.567
1.297CysGlu: 1.297 ± 0.668
0.519CysPhe: 0.519 ± 0.284
0.259CysGly: 0.259 ± 0.365
0.778CysHis: 0.778 ± 0.635
1.297CysIle: 1.297 ± 0.678
0.778CysLys: 0.778 ± 0.408
1.297CysLeu: 1.297 ± 0.426
0.778CysMet: 0.778 ± 0.367
1.037CysAsn: 1.037 ± 0.567
2.075CysPro: 2.075 ± 0.859
0.519CysGln: 0.519 ± 0.478
1.815CysArg: 1.815 ± 0.814
1.815CysSer: 1.815 ± 0.604
0.519CysThr: 0.519 ± 0.309
0.519CysVal: 0.519 ± 0.284
0.0CysTrp: 0.0 ± 0.0
0.778CysTyr: 0.778 ± 0.275
0.0CysXaa: 0.0 ± 0.0
Asp
3.112AspAla: 3.112 ± 0.625
1.037AspCys: 1.037 ± 0.5
3.89AspAsp: 3.89 ± 1.046
3.631AspGlu: 3.631 ± 0.577
2.075AspPhe: 2.075 ± 0.899
2.593AspGly: 2.593 ± 0.661
0.519AspHis: 0.519 ± 0.25
5.965AspIle: 5.965 ± 1.261
2.334AspLys: 2.334 ± 0.508
6.483AspLeu: 6.483 ± 0.948
1.815AspMet: 1.815 ± 0.814
1.815AspAsn: 1.815 ± 0.627
3.371AspPro: 3.371 ± 0.717
2.593AspGln: 2.593 ± 0.609
1.556AspArg: 1.556 ± 0.851
5.965AspSer: 5.965 ± 1.404
4.409AspThr: 4.409 ± 1.328
3.371AspVal: 3.371 ± 0.357
3.112AspTrp: 3.112 ± 1.434
2.593AspTyr: 2.593 ± 0.448
0.0AspXaa: 0.0 ± 0.0
Glu
3.112GluAla: 3.112 ± 1.157
1.037GluCys: 1.037 ± 0.752
3.631GluAsp: 3.631 ± 0.771
2.853GluGlu: 2.853 ± 0.925
2.075GluPhe: 2.075 ± 0.625
2.593GluGly: 2.593 ± 0.873
2.593GluHis: 2.593 ± 0.485
4.409GluIle: 4.409 ± 1.503
4.149GluLys: 4.149 ± 1.371
5.965GluLeu: 5.965 ± 1.81
1.556GluMet: 1.556 ± 0.462
3.112GluAsn: 3.112 ± 0.517
3.371GluPro: 3.371 ± 1.093
1.297GluGln: 1.297 ± 0.517
3.112GluArg: 3.112 ± 0.601
5.187GluSer: 5.187 ± 1.271
4.668GluThr: 4.668 ± 1.167
2.853GluVal: 2.853 ± 0.674
1.037GluTrp: 1.037 ± 0.618
1.037GluTyr: 1.037 ± 0.722
0.0GluXaa: 0.0 ± 0.0
Phe
2.334PheAla: 2.334 ± 1.196
0.259PheCys: 0.259 ± 0.365
2.334PheAsp: 2.334 ± 0.435
0.778PheGlu: 0.778 ± 0.302
0.778PhePhe: 0.778 ± 0.464
2.334PheGly: 2.334 ± 0.692
0.259PheHis: 0.259 ± 0.155
1.815PheIle: 1.815 ± 0.853
2.593PheLys: 2.593 ± 1.257
2.593PheLeu: 2.593 ± 0.364
0.778PheMet: 0.778 ± 0.464
1.297PheAsn: 1.297 ± 0.38
1.815PhePro: 1.815 ± 0.821
1.556PheGln: 1.556 ± 0.517
1.556PheArg: 1.556 ± 0.506
4.668PheSer: 4.668 ± 0.703
1.556PheThr: 1.556 ± 0.363
1.297PheVal: 1.297 ± 0.369
0.259PheTrp: 0.259 ± 0.365
1.037PheTyr: 1.037 ± 0.618
0.0PheXaa: 0.0 ± 0.0
Gly
3.89GlyAla: 3.89 ± 0.779
1.297GlyCys: 1.297 ± 0.85
2.334GlyAsp: 2.334 ± 1.124
2.593GlyGlu: 2.593 ± 1.018
1.815GlyPhe: 1.815 ± 0.826
2.334GlyGly: 2.334 ± 0.792
1.297GlyHis: 1.297 ± 0.583
3.631GlyIle: 3.631 ± 1.525
4.668GlyLys: 4.668 ± 0.66
6.483GlyLeu: 6.483 ± 0.904
2.593GlyMet: 2.593 ± 0.485
2.334GlyAsn: 2.334 ± 0.673
1.556GlyPro: 1.556 ± 1.361
1.037GlyGln: 1.037 ± 0.567
2.593GlyArg: 2.593 ± 0.665
3.89GlySer: 3.89 ± 1.089
3.89GlyThr: 3.89 ± 1.526
4.927GlyVal: 4.927 ± 1.049
1.037GlyTrp: 1.037 ± 0.344
2.075GlyTyr: 2.075 ± 0.479
0.0GlyXaa: 0.0 ± 0.0
His
0.259HisAla: 0.259 ± 0.286
0.259HisCys: 0.259 ± 0.368
2.075HisAsp: 2.075 ± 0.689
1.037HisGlu: 1.037 ± 0.888
0.519HisPhe: 0.519 ± 0.309
1.556HisGly: 1.556 ± 0.888
0.778HisHis: 0.778 ± 0.364
1.556HisIle: 1.556 ± 0.331
1.037HisLys: 1.037 ± 0.291
2.334HisLeu: 2.334 ± 0.846
0.259HisMet: 0.259 ± 0.155
1.037HisAsn: 1.037 ± 0.365
1.297HisPro: 1.297 ± 0.443
1.297HisGln: 1.297 ± 0.426
1.037HisArg: 1.037 ± 0.618
0.259HisSer: 0.259 ± 0.365
1.037HisThr: 1.037 ± 0.528
1.556HisVal: 1.556 ± 0.345
0.519HisTrp: 0.519 ± 0.284
1.556HisTyr: 1.556 ± 0.55
0.0HisXaa: 0.0 ± 0.0
Ile
4.149IleAla: 4.149 ± 1.428
1.037IleCys: 1.037 ± 0.291
2.853IleAsp: 2.853 ± 1.184
4.149IleGlu: 4.149 ± 1.534
2.334IlePhe: 2.334 ± 1.124
4.409IleGly: 4.409 ± 0.85
1.037IleHis: 1.037 ± 0.409
4.668IleIle: 4.668 ± 1.238
4.668IleLys: 4.668 ± 1.085
4.927IleLeu: 4.927 ± 1.121
3.631IleMet: 3.631 ± 0.893
3.112IleAsn: 3.112 ± 0.913
4.149IlePro: 4.149 ± 0.931
2.334IleGln: 2.334 ± 0.939
2.593IleArg: 2.593 ± 0.342
5.446IleSer: 5.446 ± 1.174
4.927IleThr: 4.927 ± 0.887
3.371IleVal: 3.371 ± 0.922
0.778IleTrp: 0.778 ± 0.464
1.556IleTyr: 1.556 ± 0.925
0.0IleXaa: 0.0 ± 0.0
Lys
3.631LysAla: 3.631 ± 0.92
0.778LysCys: 0.778 ± 0.275
2.593LysAsp: 2.593 ± 0.356
5.705LysGlu: 5.705 ± 1.016
1.556LysPhe: 1.556 ± 0.363
6.743LysGly: 6.743 ± 1.276
1.037LysHis: 1.037 ± 0.449
3.631LysIle: 3.631 ± 0.729
4.927LysLys: 4.927 ± 1.631
4.149LysLeu: 4.149 ± 0.681
2.334LysMet: 2.334 ± 1.089
3.112LysAsn: 3.112 ± 0.687
2.334LysPro: 2.334 ± 0.681
1.297LysGln: 1.297 ± 0.551
3.112LysArg: 3.112 ± 1.07
5.187LysSer: 5.187 ± 0.328
5.187LysThr: 5.187 ± 1.3
3.112LysVal: 3.112 ± 0.998
0.778LysTrp: 0.778 ± 0.364
2.593LysTyr: 2.593 ± 0.752
0.0LysXaa: 0.0 ± 0.0
Leu
4.927LeuAla: 4.927 ± 1.416
2.334LeuCys: 2.334 ± 0.795
7.521LeuAsp: 7.521 ± 1.257
3.631LeuGlu: 3.631 ± 0.759
4.668LeuPhe: 4.668 ± 1.765
5.705LeuGly: 5.705 ± 1.211
2.075LeuHis: 2.075 ± 1.356
6.224LeuIle: 6.224 ± 1.141
5.705LeuLys: 5.705 ± 1.375
8.558LeuLeu: 8.558 ± 1.681
3.631LeuMet: 3.631 ± 1.622
2.593LeuAsn: 2.593 ± 0.473
3.371LeuPro: 3.371 ± 0.988
2.075LeuGln: 2.075 ± 0.394
7.002LeuArg: 7.002 ± 1.247
8.299LeuSer: 8.299 ± 1.792
6.224LeuThr: 6.224 ± 1.593
5.965LeuVal: 5.965 ± 1.926
1.037LeuTrp: 1.037 ± 0.29
2.853LeuTyr: 2.853 ± 1.042
0.0LeuXaa: 0.0 ± 0.0
Met
1.297MetAla: 1.297 ± 0.616
0.259MetCys: 0.259 ± 0.155
2.334MetAsp: 2.334 ± 0.658
3.631MetGlu: 3.631 ± 0.399
0.259MetPhe: 0.259 ± 0.155
1.556MetGly: 1.556 ± 0.412
0.519MetHis: 0.519 ± 0.478
2.075MetIle: 2.075 ± 0.767
2.075MetLys: 2.075 ± 0.683
2.593MetLeu: 2.593 ± 0.591
0.778MetMet: 0.778 ± 0.464
1.556MetAsn: 1.556 ± 0.59
0.778MetPro: 0.778 ± 0.275
0.519MetGln: 0.519 ± 0.317
4.149MetArg: 4.149 ± 1.076
2.853MetSer: 2.853 ± 0.539
2.593MetThr: 2.593 ± 0.73
1.556MetVal: 1.556 ± 0.433
0.778MetTrp: 0.778 ± 0.464
0.519MetTyr: 0.519 ± 0.309
0.0MetXaa: 0.0 ± 0.0
Asn
2.334AsnAla: 2.334 ± 0.508
2.075AsnCys: 2.075 ± 1.142
2.334AsnAsp: 2.334 ± 0.57
1.297AsnGlu: 1.297 ± 0.393
0.519AsnPhe: 0.519 ± 0.331
1.815AsnGly: 1.815 ± 0.615
2.075AsnHis: 2.075 ± 0.444
1.815AsnIle: 1.815 ± 0.501
2.075AsnLys: 2.075 ± 1.0
3.371AsnLeu: 3.371 ± 0.845
1.037AsnMet: 1.037 ± 0.372
1.297AsnAsn: 1.297 ± 0.443
3.112AsnPro: 3.112 ± 0.695
1.297AsnGln: 1.297 ± 0.773
3.371AsnArg: 3.371 ± 0.597
2.075AsnSer: 2.075 ± 0.518
2.334AsnThr: 2.334 ± 0.393
1.815AsnVal: 1.815 ± 0.443
1.037AsnTrp: 1.037 ± 0.372
1.297AsnTyr: 1.297 ± 0.54
0.0AsnXaa: 0.0 ± 0.0
Pro
2.075ProAla: 2.075 ± 0.744
0.0ProCys: 0.0 ± 0.0
3.371ProAsp: 3.371 ± 1.178
4.927ProGlu: 4.927 ± 0.981
1.037ProPhe: 1.037 ± 0.397
1.556ProGly: 1.556 ± 0.712
1.556ProHis: 1.556 ± 0.598
2.593ProIle: 2.593 ± 0.779
2.593ProLys: 2.593 ± 1.005
5.446ProLeu: 5.446 ± 1.265
1.037ProMet: 1.037 ± 0.393
1.556ProAsn: 1.556 ± 0.331
1.815ProPro: 1.815 ± 0.609
1.556ProGln: 1.556 ± 0.68
1.556ProArg: 1.556 ± 0.68
3.371ProSer: 3.371 ± 1.673
3.89ProThr: 3.89 ± 0.699
3.371ProVal: 3.371 ± 0.521
0.259ProTrp: 0.259 ± 0.155
1.556ProTyr: 1.556 ± 0.927
0.0ProXaa: 0.0 ± 0.0
Gln
1.556GlnAla: 1.556 ± 0.363
0.778GlnCys: 0.778 ± 1.094
0.519GlnAsp: 0.519 ± 0.73
1.815GlnGlu: 1.815 ± 0.476
0.259GlnPhe: 0.259 ± 0.286
3.371GlnGly: 3.371 ± 1.014
0.0GlnHis: 0.0 ± 0.0
1.815GlnIle: 1.815 ± 0.563
1.297GlnLys: 1.297 ± 0.347
3.371GlnLeu: 3.371 ± 0.858
0.519GlnMet: 0.519 ± 0.543
1.556GlnAsn: 1.556 ± 0.613
1.297GlnPro: 1.297 ± 0.517
1.037GlnGln: 1.037 ± 0.568
1.556GlnArg: 1.556 ± 0.696
2.334GlnSer: 2.334 ± 0.922
1.037GlnThr: 1.037 ± 0.344
3.371GlnVal: 3.371 ± 0.531
0.259GlnTrp: 0.259 ± 0.155
1.297GlnTyr: 1.297 ± 0.633
0.0GlnXaa: 0.0 ± 0.0
Arg
2.853ArgAla: 2.853 ± 1.363
1.556ArgCys: 1.556 ± 0.598
2.334ArgAsp: 2.334 ± 0.882
3.89ArgGlu: 3.89 ± 0.967
2.075ArgPhe: 2.075 ± 0.386
3.112ArgGly: 3.112 ± 1.19
0.519ArgHis: 0.519 ± 0.317
3.89ArgIle: 3.89 ± 1.231
4.149ArgLys: 4.149 ± 0.675
5.187ArgLeu: 5.187 ± 2.031
1.556ArgMet: 1.556 ± 0.55
3.112ArgAsn: 3.112 ± 0.673
1.815ArgPro: 1.815 ± 0.488
1.556ArgGln: 1.556 ± 0.345
4.149ArgArg: 4.149 ± 0.494
4.668ArgSer: 4.668 ± 0.782
2.334ArgThr: 2.334 ± 1.034
4.149ArgVal: 4.149 ± 0.773
0.778ArgTrp: 0.778 ± 0.464
1.815ArgTyr: 1.815 ± 0.799
0.0ArgXaa: 0.0 ± 0.0
Ser
3.89SerAla: 3.89 ± 1.316
0.778SerCys: 0.778 ± 0.464
7.002SerAsp: 7.002 ± 0.941
5.705SerGlu: 5.705 ± 1.11
2.853SerPhe: 2.853 ± 1.08
4.149SerGly: 4.149 ± 0.626
2.075SerHis: 2.075 ± 1.706
4.409SerIle: 4.409 ± 0.852
6.224SerLys: 6.224 ± 1.517
8.039SerLeu: 8.039 ± 2.082
3.631SerMet: 3.631 ± 1.073
1.815SerAsn: 1.815 ± 0.573
2.075SerPro: 2.075 ± 0.747
3.371SerGln: 3.371 ± 1.568
4.149SerArg: 4.149 ± 0.681
10.114SerSer: 10.114 ± 2.866
5.965SerThr: 5.965 ± 0.704
4.927SerVal: 4.927 ± 1.043
1.297SerTrp: 1.297 ± 0.29
3.631SerTyr: 3.631 ± 0.553
0.0SerXaa: 0.0 ± 0.0
Thr
3.631ThrAla: 3.631 ± 0.487
1.815ThrCys: 1.815 ± 0.511
4.149ThrAsp: 4.149 ± 1.016
5.705ThrGlu: 5.705 ± 1.836
1.556ThrPhe: 1.556 ± 0.558
2.853ThrGly: 2.853 ± 0.639
1.297ThrHis: 1.297 ± 0.537
3.631ThrIle: 3.631 ± 1.086
3.371ThrLys: 3.371 ± 1.095
6.743ThrLeu: 6.743 ± 1.471
1.556ThrMet: 1.556 ± 0.696
2.075ThrAsn: 2.075 ± 0.455
3.631ThrPro: 3.631 ± 0.828
2.075ThrGln: 2.075 ± 1.325
3.631ThrArg: 3.631 ± 0.722
6.483ThrSer: 6.483 ± 1.253
3.371ThrThr: 3.371 ± 0.597
5.705ThrVal: 5.705 ± 1.217
1.556ThrTrp: 1.556 ± 0.932
1.815ThrTyr: 1.815 ± 0.262
0.0ThrXaa: 0.0 ± 0.0
Val
4.409ValAla: 4.409 ± 2.343
0.778ValCys: 0.778 ± 0.275
2.593ValAsp: 2.593 ± 0.718
2.593ValGlu: 2.593 ± 0.478
3.112ValPhe: 3.112 ± 1.195
2.334ValGly: 2.334 ± 1.056
0.519ValHis: 0.519 ± 0.25
4.149ValIle: 4.149 ± 0.947
3.631ValLys: 3.631 ± 1.193
7.521ValLeu: 7.521 ± 1.042
1.815ValMet: 1.815 ± 0.333
2.593ValAsn: 2.593 ± 0.852
3.112ValPro: 3.112 ± 0.893
1.037ValGln: 1.037 ± 0.567
3.371ValArg: 3.371 ± 0.54
6.743ValSer: 6.743 ± 1.559
6.224ValThr: 6.224 ± 0.686
4.149ValVal: 4.149 ± 0.62
1.297ValTrp: 1.297 ± 1.103
2.853ValTyr: 2.853 ± 1.427
0.0ValXaa: 0.0 ± 0.0
Trp
1.556TrpAla: 1.556 ± 0.363
0.0TrpCys: 0.0 ± 0.0
1.815TrpAsp: 1.815 ± 1.289
0.778TrpGlu: 0.778 ± 0.422
0.778TrpPhe: 0.778 ± 0.364
1.556TrpGly: 1.556 ± 0.927
0.0TrpHis: 0.0 ± 0.0
1.815TrpIle: 1.815 ± 0.604
1.037TrpLys: 1.037 ± 0.618
1.297TrpLeu: 1.297 ± 0.537
0.0TrpMet: 0.0 ± 0.0
0.519TrpAsn: 0.519 ± 0.309
0.519TrpPro: 0.519 ± 0.309
0.259TrpGln: 0.259 ± 0.365
1.297TrpArg: 1.297 ± 0.555
0.778TrpSer: 0.778 ± 0.364
0.519TrpThr: 0.519 ± 0.25
1.037TrpVal: 1.037 ± 0.409
0.259TrpTrp: 0.259 ± 0.155
1.037TrpTyr: 1.037 ± 0.528
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.334TyrAla: 2.334 ± 0.524
0.259TyrCys: 0.259 ± 0.286
3.89TyrAsp: 3.89 ± 0.676
1.556TyrGlu: 1.556 ± 0.603
1.815TyrPhe: 1.815 ± 0.64
1.297TyrGly: 1.297 ± 0.29
1.297TyrHis: 1.297 ± 0.458
1.815TyrIle: 1.815 ± 1.035
2.075TyrLys: 2.075 ± 0.689
3.631TyrLeu: 3.631 ± 0.824
1.037TyrMet: 1.037 ± 0.291
1.037TyrAsn: 1.037 ± 0.662
2.075TyrPro: 2.075 ± 0.74
0.259TyrGln: 0.259 ± 0.368
1.556TyrArg: 1.556 ± 0.46
2.334TyrSer: 2.334 ± 0.791
2.075TyrThr: 2.075 ± 0.394
3.631TyrVal: 3.631 ± 0.618
0.519TyrTrp: 0.519 ± 0.284
0.519TyrTyr: 0.519 ± 0.331
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3857 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski