Amino acid dipepetide frequency for Salmonella phage 101962B_sal5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.534AlaAla: 8.534 ± 1.207
1.343AlaCys: 1.343 ± 0.378
6.242AlaAsp: 6.242 ± 0.903
6.479AlaGlu: 6.479 ± 0.795
3.24AlaPhe: 3.24 ± 0.559
6.716AlaGly: 6.716 ± 0.787
1.106AlaHis: 1.106 ± 0.315
6.163AlaIle: 6.163 ± 0.734
5.373AlaLys: 5.373 ± 0.735
6.558AlaLeu: 6.558 ± 0.925
3.477AlaMet: 3.477 ± 0.669
6.163AlaAsn: 6.163 ± 0.924
2.37AlaPro: 2.37 ± 0.359
3.319AlaGln: 3.319 ± 0.566
5.136AlaArg: 5.136 ± 0.669
4.741AlaSer: 4.741 ± 0.61
4.82AlaThr: 4.82 ± 0.634
5.452AlaVal: 5.452 ± 0.577
1.422AlaTrp: 1.422 ± 0.354
2.133AlaTyr: 2.133 ± 0.377
0.0AlaXaa: 0.0 ± 0.0
Cys
0.711CysAla: 0.711 ± 0.286
0.237CysCys: 0.237 ± 0.134
0.395CysAsp: 0.395 ± 0.181
0.632CysGlu: 0.632 ± 0.218
0.474CysPhe: 0.474 ± 0.212
1.264CysGly: 1.264 ± 0.359
0.395CysHis: 0.395 ± 0.176
1.027CysIle: 1.027 ± 0.298
0.395CysLys: 0.395 ± 0.185
0.632CysLeu: 0.632 ± 0.289
0.158CysMet: 0.158 ± 0.11
0.474CysAsn: 0.474 ± 0.206
0.237CysPro: 0.237 ± 0.131
0.395CysGln: 0.395 ± 0.183
1.106CysArg: 1.106 ± 0.264
0.474CysSer: 0.474 ± 0.181
0.474CysThr: 0.474 ± 0.211
1.027CysVal: 1.027 ± 0.292
0.158CysTrp: 0.158 ± 0.107
0.474CysTyr: 0.474 ± 0.185
0.0CysXaa: 0.0 ± 0.0
Asp
6.953AspAla: 6.953 ± 0.835
0.395AspCys: 0.395 ± 0.192
3.477AspAsp: 3.477 ± 0.462
3.872AspGlu: 3.872 ± 0.685
1.975AspPhe: 1.975 ± 0.361
5.057AspGly: 5.057 ± 0.757
0.948AspHis: 0.948 ± 0.315
4.267AspIle: 4.267 ± 0.52
3.319AspLys: 3.319 ± 0.485
5.373AspLeu: 5.373 ± 0.707
1.659AspMet: 1.659 ± 0.355
2.291AspAsn: 2.291 ± 0.473
1.738AspPro: 1.738 ± 0.411
1.422AspGln: 1.422 ± 0.308
1.975AspArg: 1.975 ± 0.417
3.161AspSer: 3.161 ± 0.504
1.896AspThr: 1.896 ± 0.397
3.951AspVal: 3.951 ± 0.696
1.106AspTrp: 1.106 ± 0.291
2.924AspTyr: 2.924 ± 0.471
0.0AspXaa: 0.0 ± 0.0
Glu
5.531GluAla: 5.531 ± 0.699
1.343GluCys: 1.343 ± 0.293
2.924GluAsp: 2.924 ± 0.518
4.188GluGlu: 4.188 ± 0.738
2.37GluPhe: 2.37 ± 0.586
3.082GluGly: 3.082 ± 0.464
1.264GluHis: 1.264 ± 0.296
3.872GluIle: 3.872 ± 0.573
3.793GluLys: 3.793 ± 0.556
6.005GluLeu: 6.005 ± 0.711
2.133GluMet: 2.133 ± 0.399
3.003GluAsn: 3.003 ± 0.571
2.765GluPro: 2.765 ± 0.48
3.872GluGln: 3.872 ± 0.595
4.346GluArg: 4.346 ± 0.63
3.082GluSer: 3.082 ± 0.414
2.924GluThr: 2.924 ± 0.457
3.398GluVal: 3.398 ± 0.535
1.738GluTrp: 1.738 ± 0.411
2.291GluTyr: 2.291 ± 0.438
0.0GluXaa: 0.0 ± 0.0
Phe
2.845PheAla: 2.845 ± 0.447
0.632PheCys: 0.632 ± 0.2
1.975PheAsp: 1.975 ± 0.439
2.133PheGlu: 2.133 ± 0.424
1.501PhePhe: 1.501 ± 0.438
2.765PheGly: 2.765 ± 0.402
0.237PheHis: 0.237 ± 0.132
2.845PheIle: 2.845 ± 0.651
2.054PheLys: 2.054 ± 0.403
1.975PheLeu: 1.975 ± 0.4
1.343PheMet: 1.343 ± 0.248
2.133PheAsn: 2.133 ± 0.406
1.501PhePro: 1.501 ± 0.32
1.185PheGln: 1.185 ± 0.357
2.054PheArg: 2.054 ± 0.447
3.24PheSer: 3.24 ± 0.478
2.37PheThr: 2.37 ± 0.396
1.738PheVal: 1.738 ± 0.291
0.711PheTrp: 0.711 ± 0.202
1.501PheTyr: 1.501 ± 0.395
0.0PheXaa: 0.0 ± 0.0
Gly
5.768GlyAla: 5.768 ± 1.023
0.553GlyCys: 0.553 ± 0.169
4.188GlyAsp: 4.188 ± 0.591
3.556GlyGlu: 3.556 ± 0.502
2.607GlyPhe: 2.607 ± 0.533
5.689GlyGly: 5.689 ± 0.998
0.869GlyHis: 0.869 ± 0.262
4.82GlyIle: 4.82 ± 0.743
4.82GlyLys: 4.82 ± 0.643
5.373GlyLeu: 5.373 ± 0.791
2.845GlyMet: 2.845 ± 0.541
3.082GlyAsn: 3.082 ± 0.558
0.948GlyPro: 0.948 ± 0.264
3.477GlyGln: 3.477 ± 0.695
5.373GlyArg: 5.373 ± 0.74
3.951GlySer: 3.951 ± 0.832
3.556GlyThr: 3.556 ± 0.541
5.847GlyVal: 5.847 ± 0.67
2.054GlyTrp: 2.054 ± 0.406
1.817GlyTyr: 1.817 ± 0.345
0.0GlyXaa: 0.0 ± 0.0
His
1.027HisAla: 1.027 ± 0.295
0.316HisCys: 0.316 ± 0.157
0.79HisAsp: 0.79 ± 0.256
1.264HisGlu: 1.264 ± 0.384
0.632HisPhe: 0.632 ± 0.186
1.027HisGly: 1.027 ± 0.312
0.474HisHis: 0.474 ± 0.249
0.711HisIle: 0.711 ± 0.215
0.711HisLys: 0.711 ± 0.256
1.738HisLeu: 1.738 ± 0.424
0.474HisMet: 0.474 ± 0.173
0.395HisAsn: 0.395 ± 0.158
0.948HisPro: 0.948 ± 0.255
0.869HisGln: 0.869 ± 0.222
1.264HisArg: 1.264 ± 0.338
0.711HisSer: 0.711 ± 0.215
0.474HisThr: 0.474 ± 0.2
1.185HisVal: 1.185 ± 0.305
0.316HisTrp: 0.316 ± 0.144
0.553HisTyr: 0.553 ± 0.214
0.0HisXaa: 0.0 ± 0.0
Ile
6.4IleAla: 6.4 ± 0.736
0.553IleCys: 0.553 ± 0.199
3.477IleAsp: 3.477 ± 0.462
4.425IleGlu: 4.425 ± 0.647
2.054IlePhe: 2.054 ± 0.507
5.057IleGly: 5.057 ± 0.656
1.264IleHis: 1.264 ± 0.303
4.188IleIle: 4.188 ± 0.888
3.477IleLys: 3.477 ± 0.607
4.267IleLeu: 4.267 ± 0.602
1.422IleMet: 1.422 ± 0.351
3.24IleAsn: 3.24 ± 0.501
3.003IlePro: 3.003 ± 0.555
2.291IleGln: 2.291 ± 0.472
3.793IleArg: 3.793 ± 0.454
5.215IleSer: 5.215 ± 0.805
4.425IleThr: 4.425 ± 0.662
3.003IleVal: 3.003 ± 0.541
0.632IleTrp: 0.632 ± 0.202
2.291IleTyr: 2.291 ± 0.497
0.0IleXaa: 0.0 ± 0.0
Lys
4.662LysAla: 4.662 ± 0.7
0.553LysCys: 0.553 ± 0.22
3.714LysAsp: 3.714 ± 0.532
4.109LysGlu: 4.109 ± 0.658
2.212LysPhe: 2.212 ± 0.401
4.109LysGly: 4.109 ± 0.521
0.869LysHis: 0.869 ± 0.289
3.082LysIle: 3.082 ± 0.486
5.136LysLys: 5.136 ± 0.856
4.741LysLeu: 4.741 ± 0.571
2.449LysMet: 2.449 ± 0.519
2.212LysAsn: 2.212 ± 0.414
4.03LysPro: 4.03 ± 0.671
3.003LysGln: 3.003 ± 0.579
4.82LysArg: 4.82 ± 0.669
3.319LysSer: 3.319 ± 0.58
3.398LysThr: 3.398 ± 0.558
2.924LysVal: 2.924 ± 0.474
0.474LysTrp: 0.474 ± 0.204
2.212LysTyr: 2.212 ± 0.411
0.0LysXaa: 0.0 ± 0.0
Leu
7.348LeuAla: 7.348 ± 0.731
0.869LeuCys: 0.869 ± 0.232
3.793LeuAsp: 3.793 ± 0.587
4.741LeuGlu: 4.741 ± 0.497
2.845LeuPhe: 2.845 ± 0.463
4.741LeuGly: 4.741 ± 0.822
1.106LeuHis: 1.106 ± 0.283
6.084LeuIle: 6.084 ± 0.727
5.531LeuLys: 5.531 ± 0.678
6.558LeuLeu: 6.558 ± 0.877
2.765LeuMet: 2.765 ± 0.35
4.662LeuAsn: 4.662 ± 0.605
3.082LeuPro: 3.082 ± 0.509
2.765LeuGln: 2.765 ± 0.498
4.425LeuArg: 4.425 ± 0.606
5.847LeuSer: 5.847 ± 0.751
4.662LeuThr: 4.662 ± 0.627
4.899LeuVal: 4.899 ± 0.588
1.185LeuTrp: 1.185 ± 0.284
2.607LeuTyr: 2.607 ± 0.484
0.0LeuXaa: 0.0 ± 0.0
Met
3.003MetAla: 3.003 ± 0.444
0.395MetCys: 0.395 ± 0.206
1.501MetAsp: 1.501 ± 0.379
1.343MetGlu: 1.343 ± 0.323
0.632MetPhe: 0.632 ± 0.255
1.817MetGly: 1.817 ± 0.331
0.158MetHis: 0.158 ± 0.118
1.659MetIle: 1.659 ± 0.417
3.082MetLys: 3.082 ± 0.539
2.212MetLeu: 2.212 ± 0.341
1.027MetMet: 1.027 ± 0.348
1.264MetAsn: 1.264 ± 0.337
1.027MetPro: 1.027 ± 0.299
1.738MetGln: 1.738 ± 0.38
2.765MetArg: 2.765 ± 0.577
2.528MetSer: 2.528 ± 0.444
2.212MetThr: 2.212 ± 0.445
1.659MetVal: 1.659 ± 0.339
0.158MetTrp: 0.158 ± 0.074
1.185MetTyr: 1.185 ± 0.32
0.0MetXaa: 0.0 ± 0.0
Asn
4.741AsnAla: 4.741 ± 0.831
0.079AsnCys: 0.079 ± 0.089
2.765AsnAsp: 2.765 ± 0.45
3.003AsnGlu: 3.003 ± 0.512
1.343AsnPhe: 1.343 ± 0.312
4.583AsnGly: 4.583 ± 0.55
1.027AsnHis: 1.027 ± 0.32
2.765AsnIle: 2.765 ± 0.463
2.845AsnLys: 2.845 ± 0.542
2.765AsnLeu: 2.765 ± 0.492
1.501AsnMet: 1.501 ± 0.346
2.528AsnAsn: 2.528 ± 0.472
3.003AsnPro: 3.003 ± 0.491
2.054AsnGln: 2.054 ± 0.504
2.212AsnArg: 2.212 ± 0.433
2.607AsnSer: 2.607 ± 0.43
2.924AsnThr: 2.924 ± 0.584
3.082AsnVal: 3.082 ± 0.683
0.474AsnTrp: 0.474 ± 0.168
1.343AsnTyr: 1.343 ± 0.352
0.0AsnXaa: 0.0 ± 0.0
Pro
2.765ProAla: 2.765 ± 0.371
0.079ProCys: 0.079 ± 0.082
3.003ProAsp: 3.003 ± 0.452
4.583ProGlu: 4.583 ± 0.591
1.738ProPhe: 1.738 ± 0.329
2.054ProGly: 2.054 ± 0.339
0.711ProHis: 0.711 ± 0.248
2.291ProIle: 2.291 ± 0.419
2.37ProLys: 2.37 ± 0.392
3.24ProLeu: 3.24 ± 0.458
1.106ProMet: 1.106 ± 0.293
1.343ProAsn: 1.343 ± 0.352
1.659ProPro: 1.659 ± 0.413
1.738ProGln: 1.738 ± 0.352
2.054ProArg: 2.054 ± 0.361
2.845ProSer: 2.845 ± 0.437
1.659ProThr: 1.659 ± 0.275
3.398ProVal: 3.398 ± 0.543
0.395ProTrp: 0.395 ± 0.189
0.869ProTyr: 0.869 ± 0.289
0.0ProXaa: 0.0 ± 0.0
Gln
4.03GlnAla: 4.03 ± 0.486
0.474GlnCys: 0.474 ± 0.201
2.765GlnAsp: 2.765 ± 0.469
2.607GlnGlu: 2.607 ± 0.519
1.58GlnPhe: 1.58 ± 0.404
3.003GlnGly: 3.003 ± 0.594
0.79GlnHis: 0.79 ± 0.237
3.082GlnIle: 3.082 ± 0.447
1.58GlnLys: 1.58 ± 0.354
4.109GlnLeu: 4.109 ± 0.474
1.264GlnMet: 1.264 ± 0.328
1.896GlnAsn: 1.896 ± 0.692
1.659GlnPro: 1.659 ± 0.29
3.24GlnGln: 3.24 ± 0.961
2.765GlnArg: 2.765 ± 0.477
2.528GlnSer: 2.528 ± 0.515
1.501GlnThr: 1.501 ± 0.362
2.449GlnVal: 2.449 ± 0.553
0.79GlnTrp: 0.79 ± 0.231
1.817GlnTyr: 1.817 ± 0.456
0.0GlnXaa: 0.0 ± 0.0
Arg
4.662ArgAla: 4.662 ± 0.489
0.553ArgCys: 0.553 ± 0.185
4.109ArgAsp: 4.109 ± 0.602
4.346ArgGlu: 4.346 ± 0.594
2.054ArgPhe: 2.054 ± 0.443
3.319ArgGly: 3.319 ± 0.501
1.422ArgHis: 1.422 ± 0.316
4.425ArgIle: 4.425 ± 0.63
4.109ArgLys: 4.109 ± 0.701
5.373ArgLeu: 5.373 ± 0.689
2.212ArgMet: 2.212 ± 0.349
3.319ArgAsn: 3.319 ± 0.557
2.291ArgPro: 2.291 ± 0.413
2.291ArgGln: 2.291 ± 0.445
4.109ArgArg: 4.109 ± 0.752
3.635ArgSer: 3.635 ± 0.449
1.975ArgThr: 1.975 ± 0.384
3.161ArgVal: 3.161 ± 0.517
0.79ArgTrp: 0.79 ± 0.256
2.133ArgTyr: 2.133 ± 0.539
0.0ArgXaa: 0.0 ± 0.0
Ser
6.005SerAla: 6.005 ± 1.057
0.632SerCys: 0.632 ± 0.296
3.319SerAsp: 3.319 ± 0.512
3.477SerGlu: 3.477 ± 0.565
2.924SerPhe: 2.924 ± 0.5
5.215SerGly: 5.215 ± 0.774
1.106SerHis: 1.106 ± 0.337
3.714SerIle: 3.714 ± 0.466
3.398SerLys: 3.398 ± 0.44
5.215SerLeu: 5.215 ± 0.636
1.817SerMet: 1.817 ± 0.298
2.291SerAsn: 2.291 ± 0.347
2.845SerPro: 2.845 ± 0.469
3.003SerGln: 3.003 ± 0.521
3.398SerArg: 3.398 ± 0.518
3.635SerSer: 3.635 ± 0.626
2.924SerThr: 2.924 ± 0.597
3.714SerVal: 3.714 ± 0.608
0.948SerTrp: 0.948 ± 0.263
1.975SerTyr: 1.975 ± 0.454
0.0SerXaa: 0.0 ± 0.0
Thr
5.689ThrAla: 5.689 ± 0.862
0.474ThrCys: 0.474 ± 0.199
2.845ThrAsp: 2.845 ± 0.553
2.686ThrGlu: 2.686 ± 0.516
1.817ThrPhe: 1.817 ± 0.407
4.504ThrGly: 4.504 ± 0.647
0.79ThrHis: 0.79 ± 0.182
2.765ThrIle: 2.765 ± 0.482
3.161ThrLys: 3.161 ± 0.475
4.188ThrLeu: 4.188 ± 0.651
1.027ThrMet: 1.027 ± 0.31
2.212ThrAsn: 2.212 ± 0.482
2.924ThrPro: 2.924 ± 0.417
2.449ThrGln: 2.449 ± 0.332
1.975ThrArg: 1.975 ± 0.437
3.477ThrSer: 3.477 ± 0.656
2.924ThrThr: 2.924 ± 0.516
2.845ThrVal: 2.845 ± 0.457
0.553ThrTrp: 0.553 ± 0.218
1.343ThrTyr: 1.343 ± 0.295
0.0ThrXaa: 0.0 ± 0.0
Val
5.847ValAla: 5.847 ± 0.582
1.027ValCys: 1.027 ± 0.364
3.477ValAsp: 3.477 ± 0.429
4.346ValGlu: 4.346 ± 0.563
2.845ValPhe: 2.845 ± 0.475
3.872ValGly: 3.872 ± 0.622
0.553ValHis: 0.553 ± 0.229
3.793ValIle: 3.793 ± 0.654
4.03ValLys: 4.03 ± 0.45
6.084ValLeu: 6.084 ± 0.687
1.027ValMet: 1.027 ± 0.328
3.319ValAsn: 3.319 ± 0.568
1.738ValPro: 1.738 ± 0.421
1.896ValGln: 1.896 ± 0.327
2.924ValArg: 2.924 ± 0.452
3.714ValSer: 3.714 ± 0.695
3.556ValThr: 3.556 ± 0.583
4.662ValVal: 4.662 ± 0.513
0.79ValTrp: 0.79 ± 0.226
2.054ValTyr: 2.054 ± 0.478
0.0ValXaa: 0.0 ± 0.0
Trp
1.185TrpAla: 1.185 ± 0.333
0.158TrpCys: 0.158 ± 0.123
0.711TrpAsp: 0.711 ± 0.221
0.474TrpGlu: 0.474 ± 0.191
0.316TrpPhe: 0.316 ± 0.163
1.027TrpGly: 1.027 ± 0.291
0.316TrpHis: 0.316 ± 0.159
0.553TrpIle: 0.553 ± 0.199
1.027TrpLys: 1.027 ± 0.344
1.975TrpLeu: 1.975 ± 0.514
0.869TrpMet: 0.869 ± 0.225
0.316TrpAsn: 0.316 ± 0.137
0.711TrpPro: 0.711 ± 0.228
1.027TrpGln: 1.027 ± 0.221
1.264TrpArg: 1.264 ± 0.393
1.027TrpSer: 1.027 ± 0.251
0.553TrpThr: 0.553 ± 0.192
1.027TrpVal: 1.027 ± 0.25
0.237TrpTrp: 0.237 ± 0.12
0.632TrpTyr: 0.632 ± 0.217
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.082TyrAla: 3.082 ± 0.48
0.474TyrCys: 0.474 ± 0.207
2.291TyrAsp: 2.291 ± 0.623
1.659TyrGlu: 1.659 ± 0.457
1.58TyrPhe: 1.58 ± 0.331
2.291TyrGly: 2.291 ± 0.478
0.474TyrHis: 0.474 ± 0.192
2.37TyrIle: 2.37 ± 0.489
1.817TyrLys: 1.817 ± 0.35
2.133TyrLeu: 2.133 ± 0.347
0.711TyrMet: 0.711 ± 0.259
1.501TyrAsn: 1.501 ± 0.454
1.422TyrPro: 1.422 ± 0.421
1.896TyrGln: 1.896 ± 0.447
2.528TyrArg: 2.528 ± 0.468
1.817TyrSer: 1.817 ± 0.407
1.422TyrThr: 1.422 ± 0.249
2.133TyrVal: 2.133 ± 0.406
0.474TyrTrp: 0.474 ± 0.167
1.185TyrTyr: 1.185 ± 0.294
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 64 proteins (12657 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski