Amino acid dipepetide frequency for Lysinibacillus massiliensis 4400831 = CIP 108448 = CCUG 49529

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.957AlaAla: 4.957 ± 0.099	0.61AlaCys: 0.61 ± 0.026	3.076AlaAsp: 3.076 ± 0.056	4.556AlaGlu: 4.556 ± 0.08	3.231AlaPhe: 3.231 ± 0.057	4.593AlaGly: 4.593 ± 0.079	1.188AlaHis: 1.188 ± 0.038	6.373AlaIle: 6.373 ± 0.102	4.677AlaLys: 4.677 ± 0.077	6.825AlaLeu: 6.825 ± 0.088	1.907AlaMet: 1.907 ± 0.045	3.025AlaAsn: 3.025 ± 0.05	1.918AlaPro: 1.918 ± 0.052	2.219AlaGln: 2.219 ± 0.05	2.448AlaArg: 2.448 ± 0.051	3.895AlaSer: 3.895 ± 0.078	3.685AlaThr: 3.685 ± 0.065	4.941AlaVal: 4.941 ± 0.082	0.513AlaTrp: 0.513 ± 0.023	2.194AlaTyr: 2.194 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.445CysAla: 0.445 ± 0.023	0.097CysCys: 0.097 ± 0.009	0.409CysAsp: 0.409 ± 0.022	0.505CysGlu: 0.505 ± 0.026	0.305CysPhe: 0.305 ± 0.018	0.681CysGly: 0.681 ± 0.031	0.171CysHis: 0.171 ± 0.014	0.648CysIle: 0.648 ± 0.022	0.435CysLys: 0.435 ± 0.018	0.642CysLeu: 0.642 ± 0.025	0.161CysMet: 0.161 ± 0.012	0.346CysAsn: 0.346 ± 0.022	0.323CysPro: 0.323 ± 0.018	0.188CysGln: 0.188 ± 0.013	0.262CysArg: 0.262 ± 0.017	0.502CysSer: 0.502 ± 0.023	0.386CysThr: 0.386 ± 0.02	0.393CysVal: 0.393 ± 0.02	0.073CysTrp: 0.073 ± 0.008	0.249CysTyr: 0.249 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.292AspAla: 3.292 ± 0.057	0.358AspCys: 0.358 ± 0.015	2.406AspAsp: 2.406 ± 0.06	4.674AspGlu: 4.674 ± 0.083	2.548AspPhe: 2.548 ± 0.057	3.259AspGly: 3.259 ± 0.069	0.997AspHis: 0.997 ± 0.033	4.313AspIle: 4.313 ± 0.072	3.04AspLys: 3.04 ± 0.055	4.972AspLeu: 4.972 ± 0.072	1.258AspMet: 1.258 ± 0.037	1.949AspAsn: 1.949 ± 0.044	1.779AspPro: 1.779 ± 0.038	1.759AspGln: 1.759 ± 0.038	1.968AspArg: 1.968 ± 0.048	2.791AspSer: 2.791 ± 0.05	2.458AspThr: 2.458 ± 0.05	3.772AspVal: 3.772 ± 0.064	0.533AspTrp: 0.533 ± 0.026	2.144AspTyr: 2.144 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	5.336GluAla: 5.336 ± 0.091	0.393GluCys: 0.393 ± 0.021	3.883GluAsp: 3.883 ± 0.071	7.424GluGlu: 7.424 ± 0.103	2.965GluPhe: 2.965 ± 0.054	4.262GluGly: 4.262 ± 0.069	1.533GluHis: 1.533 ± 0.037	6.566GluIle: 6.566 ± 0.087	6.55GluLys: 6.55 ± 0.085	7.442GluLeu: 7.442 ± 0.104	2.345GluMet: 2.345 ± 0.047	4.237GluAsn: 4.237 ± 0.072	1.913GluPro: 1.913 ± 0.047	3.573GluGln: 3.573 ± 0.077	3.275GluArg: 3.275 ± 0.062	3.805GluSer: 3.805 ± 0.065	3.914GluThr: 3.914 ± 0.06	5.488GluVal: 5.488 ± 0.074	0.756GluTrp: 0.756 ± 0.027	2.4GluTyr: 2.4 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	3.087PheAla: 3.087 ± 0.058	0.373PheCys: 0.373 ± 0.023	2.629PheAsp: 2.629 ± 0.052	3.359PheGlu: 3.359 ± 0.057	2.21PhePhe: 2.21 ± 0.056	3.326PheGly: 3.326 ± 0.066	0.922PheHis: 0.922 ± 0.032	4.354PheIle: 4.354 ± 0.089	2.639PheLys: 2.639 ± 0.048	4.294PheLeu: 4.294 ± 0.069	1.114PheMet: 1.114 ± 0.04	2.219PheAsn: 2.219 ± 0.051	1.568PhePro: 1.568 ± 0.042	1.537PheGln: 1.537 ± 0.036	1.483PheArg: 1.483 ± 0.042	3.18PheSer: 3.18 ± 0.07	2.713PheThr: 2.713 ± 0.056	3.328PheVal: 3.328 ± 0.064	0.409PheTrp: 0.409 ± 0.023	1.739PheTyr: 1.739 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.566GlyAla: 4.566 ± 0.079	0.562GlyCys: 0.562 ± 0.026	3.003GlyAsp: 3.003 ± 0.067	4.459GlyGlu: 4.459 ± 0.063	3.211GlyPhe: 3.211 ± 0.066	4.359GlyGly: 4.359 ± 0.09	1.322GlyHis: 1.322 ± 0.034	5.93GlyIle: 5.93 ± 0.09	4.553GlyLys: 4.553 ± 0.079	6.193GlyLeu: 6.193 ± 0.095	1.908GlyMet: 1.908 ± 0.043	2.755GlyAsn: 2.755 ± 0.056	1.573GlyPro: 1.573 ± 0.041	2.139GlyGln: 2.139 ± 0.048	2.434GlyArg: 2.434 ± 0.051	3.681GlySer: 3.681 ± 0.073	3.78GlyThr: 3.78 ± 0.07	4.94GlyVal: 4.94 ± 0.083	0.681GlyTrp: 0.681 ± 0.031	2.776GlyTyr: 2.776 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.231HisAla: 1.231 ± 0.032	0.181HisCys: 0.181 ± 0.014	0.966HisAsp: 0.966 ± 0.036	1.431HisGlu: 1.431 ± 0.038	1.002HisPhe: 1.002 ± 0.032	1.248HisGly: 1.248 ± 0.047	0.614HisHis: 0.614 ± 0.025	1.55HisIle: 1.55 ± 0.038	1.038HisLys: 1.038 ± 0.028	2.042HisLeu: 2.042 ± 0.047	0.448HisMet: 0.448 ± 0.022	0.767HisAsn: 0.767 ± 0.027	1.053HisPro: 1.053 ± 0.036	0.764HisGln: 0.764 ± 0.028	0.762HisArg: 0.762 ± 0.029	1.155HisSer: 1.155 ± 0.035	0.979HisThr: 0.979 ± 0.031	1.394HisVal: 1.394 ± 0.032	0.184HisTrp: 0.184 ± 0.016	0.815HisTyr: 0.815 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.403IleAla: 6.403 ± 0.088	0.675IleCys: 0.675 ± 0.026	4.828IleAsp: 4.828 ± 0.073	6.872IleGlu: 6.872 ± 0.104	3.724IlePhe: 3.724 ± 0.072	6.028IleGly: 6.028 ± 0.102	1.72IleHis: 1.72 ± 0.044	6.902IleIle: 6.902 ± 0.116	4.929IleLys: 4.929 ± 0.073	7.874IleLeu: 7.874 ± 0.101	1.863IleMet: 1.863 ± 0.047	3.785IleAsn: 3.785 ± 0.07	3.443IlePro: 3.443 ± 0.063	3.238IleGln: 3.238 ± 0.06	3.168IleArg: 3.168 ± 0.056	5.636IleSer: 5.636 ± 0.089	4.699IleThr: 4.699 ± 0.073	6.307IleVal: 6.307 ± 0.085	0.701IleTrp: 0.701 ± 0.028	2.76IleTyr: 2.76 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	4.22LysAla: 4.22 ± 0.068	0.416LysCys: 0.416 ± 0.023	3.632LysAsp: 3.632 ± 0.063	6.638LysGlu: 6.638 ± 0.096	2.346LysPhe: 2.346 ± 0.056	4.199LysGly: 4.199 ± 0.071	1.27LysHis: 1.27 ± 0.034	5.225LysIle: 5.225 ± 0.074	5.548LysLys: 5.548 ± 0.079	6.112LysLeu: 6.112 ± 0.082	2.19LysMet: 2.19 ± 0.047	3.783LysAsn: 3.783 ± 0.068	2.109LysPro: 2.109 ± 0.044	2.886LysGln: 2.886 ± 0.059	3.034LysArg: 3.034 ± 0.06	3.799LysSer: 3.799 ± 0.068	3.674LysThr: 3.674 ± 0.066	4.779LysVal: 4.779 ± 0.079	0.787LysTrp: 0.787 ± 0.029	2.503LysTyr: 2.503 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	6.857LeuAla: 6.857 ± 0.093	0.675LeuCys: 0.675 ± 0.023	4.7LeuAsp: 4.7 ± 0.076	6.829LeuGlu: 6.829 ± 0.092	4.816LeuPhe: 4.816 ± 0.09	6.023LeuGly: 6.023 ± 0.086	1.795LeuHis: 1.795 ± 0.043	7.796LeuIle: 7.796 ± 0.119	6.839LeuLys: 6.839 ± 0.097	9.675LeuLeu: 9.675 ± 0.139	2.394LeuMet: 2.394 ± 0.053	5.028LeuAsn: 5.028 ± 0.071	3.803LeuPro: 3.803 ± 0.062	3.642LeuGln: 3.642 ± 0.067	3.485LeuArg: 3.485 ± 0.068	6.676LeuSer: 6.676 ± 0.08	5.588LeuThr: 5.588 ± 0.081	6.116LeuVal: 6.116 ± 0.09	0.736LeuTrp: 0.736 ± 0.028	3.103LeuTyr: 3.103 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	1.723MetAla: 1.723 ± 0.054	0.161MetCys: 0.161 ± 0.012	1.37MetAsp: 1.37 ± 0.036	1.988MetGlu: 1.988 ± 0.041	1.055MetPhe: 1.055 ± 0.033	1.677MetGly: 1.677 ± 0.043	0.422MetHis: 0.422 ± 0.02	2.12MetIle: 2.12 ± 0.046	2.449MetLys: 2.449 ± 0.04	2.416MetLeu: 2.416 ± 0.054	0.776MetMet: 0.776 ± 0.029	1.532MetAsn: 1.532 ± 0.042	0.947MetPro: 0.947 ± 0.029	0.9MetGln: 0.9 ± 0.029	1.106MetArg: 1.106 ± 0.038	1.654MetSer: 1.654 ± 0.039	1.638MetThr: 1.638 ± 0.041	1.591MetVal: 1.591 ± 0.04	0.177MetTrp: 0.177 ± 0.013	0.743MetTyr: 0.743 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.038AsnAla: 3.038 ± 0.046	0.345AsnCys: 0.345 ± 0.018	2.5AsnAsp: 2.5 ± 0.054	4.247AsnGlu: 4.247 ± 0.066	1.912AsnPhe: 1.912 ± 0.045	3.461AsnGly: 3.461 ± 0.073	1.043AsnHis: 1.043 ± 0.034	4.018AsnIle: 4.018 ± 0.071	3.312AsnLys: 3.312 ± 0.066	4.327AsnLeu: 4.327 ± 0.071	1.254AsnMet: 1.254 ± 0.037	2.492AsnAsn: 2.492 ± 0.06	2.17AsnPro: 2.17 ± 0.051	1.914AsnGln: 1.914 ± 0.048	2.148AsnArg: 2.148 ± 0.05	2.71AsnSer: 2.71 ± 0.058	2.457AsnThr: 2.457 ± 0.051	3.296AsnVal: 3.296 ± 0.061	0.558AsnTrp: 0.558 ± 0.02	1.832AsnTyr: 1.832 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	1.989ProAla: 1.989 ± 0.05	0.193ProCys: 0.193 ± 0.016	1.651ProAsp: 1.651 ± 0.046	2.824ProGlu: 2.824 ± 0.06	1.987ProPhe: 1.987 ± 0.042	2.01ProGly: 2.01 ± 0.047	0.744ProHis: 0.744 ± 0.029	3.221ProIle: 3.221 ± 0.054	2.226ProLys: 2.226 ± 0.052	3.228ProLeu: 3.228 ± 0.063	0.755ProMet: 0.755 ± 0.029	1.865ProAsn: 1.865 ± 0.041	0.915ProPro: 0.915 ± 0.033	1.1ProGln: 1.1 ± 0.031	1.0ProArg: 1.0 ± 0.029	2.223ProSer: 2.223 ± 0.048	2.177ProThr: 2.177 ± 0.044	2.512ProVal: 2.512 ± 0.049	0.341ProTrp: 0.341 ± 0.021	1.426ProTyr: 1.426 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.484GlnAla: 2.484 ± 0.055	0.201GlnCys: 0.201 ± 0.015	1.567GlnAsp: 1.567 ± 0.037	2.557GlnGlu: 2.557 ± 0.06	1.751GlnPhe: 1.751 ± 0.043	1.963GlnGly: 1.963 ± 0.049	0.76GlnHis: 0.76 ± 0.029	2.995GlnIle: 2.995 ± 0.052	2.627GlnLys: 2.627 ± 0.06	4.229GlnLeu: 4.229 ± 0.072	1.171GlnMet: 1.171 ± 0.037	1.802GlnAsn: 1.802 ± 0.048	1.088GlnPro: 1.088 ± 0.034	1.69GlnGln: 1.69 ± 0.049	1.354GlnArg: 1.354 ± 0.043	2.262GlnSer: 2.262 ± 0.053	1.839GlnThr: 1.839 ± 0.049	2.424GlnVal: 2.424 ± 0.052	0.365GlnTrp: 0.365 ± 0.018	1.507GlnTyr: 1.507 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.341ArgAla: 2.341 ± 0.046	0.254ArgCys: 0.254 ± 0.015	1.948ArgAsp: 1.948 ± 0.049	3.031ArgGlu: 3.031 ± 0.055	1.836ArgPhe: 1.836 ± 0.037	2.195ArgGly: 2.195 ± 0.054	0.693ArgHis: 0.693 ± 0.025	3.14ArgIle: 3.14 ± 0.057	3.071ArgLys: 3.071 ± 0.061	3.641ArgLeu: 3.641 ± 0.063	1.152ArgMet: 1.152 ± 0.036	1.952ArgAsn: 1.952 ± 0.042	1.242ArgPro: 1.242 ± 0.037	1.448ArgGln: 1.448 ± 0.038	1.672ArgArg: 1.672 ± 0.043	2.022ArgSer: 2.022 ± 0.042	1.906ArgThr: 1.906 ± 0.04	2.551ArgVal: 2.551 ± 0.056	0.379ArgTrp: 0.379 ± 0.019	1.495ArgTyr: 1.495 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.516SerAla: 3.516 ± 0.065	0.406SerCys: 0.406 ± 0.019	2.809SerAsp: 2.809 ± 0.059	4.201SerGlu: 4.201 ± 0.062	3.382SerPhe: 3.382 ± 0.064	4.139SerGly: 4.139 ± 0.073	1.143SerHis: 1.143 ± 0.036	5.702SerIle: 5.702 ± 0.081	4.15SerLys: 4.15 ± 0.065	6.0SerLeu: 6.0 ± 0.078	1.598SerMet: 1.598 ± 0.038	3.184SerAsn: 3.184 ± 0.058	1.969SerPro: 1.969 ± 0.049	2.012SerGln: 2.012 ± 0.05	2.137SerArg: 2.137 ± 0.044	3.925SerSer: 3.925 ± 0.074	3.433SerThr: 3.433 ± 0.055	3.98SerVal: 3.98 ± 0.068	0.561SerTrp: 0.561 ± 0.026	2.266SerTyr: 2.266 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	3.698ThrAla: 3.698 ± 0.061	0.332ThrCys: 0.332 ± 0.018	2.677ThrAsp: 2.677 ± 0.058	3.794ThrGlu: 3.794 ± 0.072	2.679ThrPhe: 2.679 ± 0.052	3.794ThrGly: 3.794 ± 0.063	1.015ThrHis: 1.015 ± 0.03	5.033ThrIle: 5.033 ± 0.071	3.515ThrLys: 3.515 ± 0.065	5.304ThrLeu: 5.304 ± 0.076	1.266ThrMet: 1.266 ± 0.035	2.796ThrAsn: 2.796 ± 0.054	2.33ThrPro: 2.33 ± 0.05	1.516ThrGln: 1.516 ± 0.042	1.743ThrArg: 1.743 ± 0.037	3.342ThrSer: 3.342 ± 0.061	3.258ThrThr: 3.258 ± 0.063	4.273ThrVal: 4.273 ± 0.067	0.524ThrTrp: 0.524 ± 0.025	2.085ThrTyr: 2.085 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	4.978ValAla: 4.978 ± 0.079	0.569ValCys: 0.569 ± 0.024	3.694ValAsp: 3.694 ± 0.055	5.257ValGlu: 5.257 ± 0.086	3.084ValPhe: 3.084 ± 0.066	4.613ValGly: 4.613 ± 0.071	1.319ValHis: 1.319 ± 0.038	5.939ValIle: 5.939 ± 0.079	4.609ValLys: 4.609 ± 0.072	6.738ValLeu: 6.738 ± 0.084	1.771ValMet: 1.771 ± 0.043	3.262ValAsn: 3.262 ± 0.059	2.633ValPro: 2.633 ± 0.049	2.399ValGln: 2.399 ± 0.049	2.572ValArg: 2.572 ± 0.06	4.492ValSer: 4.492 ± 0.068	4.077ValThr: 4.077 ± 0.064	5.063ValVal: 5.063 ± 0.076	0.568ValTrp: 0.568 ± 0.022	2.306ValTyr: 2.306 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.547TrpAla: 0.547 ± 0.026	0.079TrpCys: 0.079 ± 0.009	0.486TrpAsp: 0.486 ± 0.024	0.612TrpGlu: 0.612 ± 0.024	0.488TrpPhe: 0.488 ± 0.024	0.606TrpGly: 0.606 ± 0.025	0.205TrpHis: 0.205 ± 0.014	0.887TrpIle: 0.887 ± 0.03	0.652TrpLys: 0.652 ± 0.027	1.008TrpLeu: 1.008 ± 0.034	0.31TrpMet: 0.31 ± 0.017	0.536TrpAsn: 0.536 ± 0.024	0.234TrpPro: 0.234 ± 0.014	0.337TrpGln: 0.337 ± 0.019	0.364TrpArg: 0.364 ± 0.018	0.52TrpSer: 0.52 ± 0.026	0.477TrpThr: 0.477 ± 0.023	0.568TrpVal: 0.568 ± 0.025	0.109TrpTrp: 0.109 ± 0.01	0.307TrpTyr: 0.307 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.128TyrAla: 2.128 ± 0.048	0.341TyrCys: 0.341 ± 0.018	2.036TyrAsp: 2.036 ± 0.044	2.802TyrGlu: 2.802 ± 0.056	1.95TyrPhe: 1.95 ± 0.048	2.389TyrGly: 2.389 ± 0.053	0.746TyrHis: 0.746 ± 0.027	2.84TyrIle: 2.84 ± 0.061	2.29TyrLys: 2.29 ± 0.043	3.617TyrLeu: 3.617 ± 0.068	0.805TyrMet: 0.805 ± 0.025	1.723TyrAsn: 1.723 ± 0.039	1.376TyrPro: 1.376 ± 0.037	1.373TyrGln: 1.373 ± 0.038	1.553TyrArg: 1.553 ± 0.045	2.246TyrSer: 2.246 ± 0.047	1.836TyrThr: 1.836 ± 0.041	2.226TyrVal: 2.226 ± 0.048	0.376TyrTrp: 0.376 ± 0.019	1.521TyrTyr: 1.521 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3499 proteins (1022772 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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